Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
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Άγιος Νικόλαος Κρήτη 72100
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Κυριακή 8 Μαΐου 2016

OtoRhinoLaryngology & Medicine,New Articles,May 9th,2016


Factors affecting volume change of myocutaneous flaps in oral cancer

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 9 δευτερόλεπτα
Publication date: Available online 8 May 2016 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): A. Hiraki, T. Yamamoto, R. Yoshida, M. Nagata, K. Kawahara, Y. Nakagawa, Y. Matsuoka, T. Tanaka, A. Hirosue, D. Fukuma, T. Ikebe, M. Shinohara, H. Nakayama After oral cancer resection with flap reconstruction, the volume of the flap decreases over time. The purpose of this study was to estimate the volume change in myocutaneous flaps and to identify the clinical factors associated with this volume decrease. Postoperative computed tomography scans and magnetic reson...περισσότερα »

Who shot first?

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Gunshot recordings from a criminal incident: Audio forensic examination for law enforcement and criminal justice investigations increasingly involves audiovisual recordings from dashboard camera systems, bystander smart phones, body cameras worn by police officers, and even by cameras built into TASER™ devices. If the camera is pointing in an appropriate direction the details of the incident may be found in the recorded video. However, if the camera’s field of view is limited, it may still be possible to evaluate the circumstances of interest by examining the sounds captured by th...περισσότερα »

Methods for the identification of intermittent and unpredictable noises

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Methods for the identification of intermittent and unpredictable noises: Acoustical consultants are often asked to identify noises that are intermittent and unpredictable, such that attended observation is impractical. This paper presents methods for recording and identifying such events using unattended long-term recordings of sound and vibration, and for efficiently analyzing the voluminous data that can accumulate during such studies.

Noise dosimetry of ensemble musicians

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
at Brigham Young University—Idaho: Students studying music can be exposed to high levels of sound while practicing, both the sound they create and the sound created by those around them. While playing one’s instrument and creating sound are crucial to a student’s success, the music itself and ambient sound may result in noise-induced hearing loss for the musician. We have made noise dose measurements to investigate the sound that students are exposed to while practicing in a large symphonic ensemble. Contributing factors of high volumes of sound may include students’ instruments...περισσότερα »

Is perceptual learning influenced by inherent variability of phonetic category?

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Is perceptual learning influenced by inherent variability of phonetic category?: A body of research has shown the effect of lexically guided perceptual learning (e.g., Norris et al., 2003), whereby listeners modify phonetic category boundaries after being exposed to critical words that contain segments that are phonetically ambiguous and serve as new exemplars of a target phonetic category. It has been shown that several factors constrain the extent of learning, and one recent study (Stevens et al., 2007) suggests that inherently variable phonetic categories might resist retuning.... περισσότερα »

Measuring the low-frequency response of an acoustic guitar

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Measuring the low-frequency response of an acoustic guitar: The low-frequency response of an acoustic guitar is strongly influenced by the combined behavior of the air cavity and the top plate. The sound hole–air cavity resonance (often referred to as the Helmholtz resonance) interacts with the first elastic mode of the top plate creating a coupled oscillator with two resonance frequencies that are shifted away from the frequencies of the two original, uncoupled oscillators. This effect has been modeled using finite elements for the top plate and boundary elements for the air cav... περισσότερα »

Measurable domain for crowd noise in modern stadiums and arenas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Measurable domain for crowd noise in modern stadiums and arenas: The noisegenerated by the organized fans or crowds during sporting events has created a challenge for sports facility management. The new demand for full compliance to national sports league rules on crowd noise, as well as health regulations ordinance on noise, require new methods in estimating and or measuring such environmental conditions. Given their dynamic range and possible classification, noise levels generated by large crowds have influenced the outcome of games. Recent analysis of the available data shows th...περισσότερα »

Extrinsic talker normalization via rapid accumulation of talker-specific phonetic detail

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Extrinsic talker normalization via rapid accumulation of talker-specific phonetic detail: Talker normalization makes speech processing more efficient by reducing the degrees of freedom between the highly variable acoustic realization of speech and its abstract mental representation. However, it is unknown how processing gains afforded by talker normalization depend on the amount of talker-specific information available in the preceding speech context. We explored the timecourse of extrinsic talker normalization in a series of speeded classification tasks that parametrically varie... περισσότερα »

Phonemic category formation and suppressed sensitivity to extraneous acoustic cues

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Phonemic category formation and suppressed sensitivity to extraneous acoustic cues: L2 learners are known to be sensitive to acoustic cues beyond the bare minimum required to distinguish target language phonemic contrasts. This paper examines changes in this sensitivity to such extraneous details in the acoustic signal following extended exposure to L2 input. Our Category Activation Threshold Model (CATM) posits that the acquisition of new phonological categories brings about inhibitory mechanisms that actively suppress the processing of acoustic cues not needed for phonemic dis...περισσότερα »

Evidence that hidden hearing loss does not vary systematically as a function of noise exposure in young adults with normal audiometric hearing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Evidence that hidden hearing loss does not vary systematically as a function of noise exposure in young adults with normal audiometric hearing: Cochlear synaptopathy, or “hidden hearing loss,” refers to a loss of synapses between inner hair cells and auditory nerve fibers, and is observed in rodent models as a consequence of noise exposure and/or aging. In humans, cochlear synaptopathy is not thought to be detectable by pure tone audiometry, as thresholds to soft sounds in the rodent models are not permanently elevated. One hundred and forty audiometrically normal participants belo... περισσότερα »

Early vascular complications,Atlantoaxial instability and non-progressive kyphoscoliosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Further delineation of FKBP14-related Ehlers-Danlos syndrome: A patient with early vascular complications and non-progressive kyphoscoliosis, and literature review.: Am J Med Genet A. 2016 May 5; Authors: Dordoni C, Ciaccio C, Venturini M, Calzavara-Pinton P, Ritelli M, Colombi M Abstract FKBP14-related Ehlers-Danlos syndrome (EDS) is an extremely rare recessive connective tissue disorder described for the first time in 2012 by Baumann and coworkers. The causal gene, FKBP14, encodes a member of the F506-binding family of peptidyl-prolyl cis-trans isomerases. The paucity of patien... περισσότερα »

Health behavior theories as predictors of hearing-aid uptake and outcomes

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Health behavior theories as predictors of hearing-aid uptake and outcomes: 10.3109/14992027.2016.1144240<br>Gabrielle H. Saunders Abstract *Objective*: To understand hearing behaviors of adults seeking help for the first time through the application of two models of health behavior change: the transtheoretical model and the health belief model. *Design*: The relationships between attitudes and beliefs were examined relative to hearing-aid uptake and outcomes six months later. *Study sample:* One hundred and sixty adults completed the University of Rhode Island change assessment ...περισσότερα »

Interventions for tinnitus: Application of taxonomies from health psychology

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
A systematic review of techniques and effects of self-help interventions for tinnitus: Application of taxonomies from health psychology: 10.3109/14992027.2015.1137363<br>Kate Greenwell Abstract *Objective*: Self-help interventions are followed by people independently with minimal or no therapist contact. This review aims to assess the effectiveness of self-help interventions for adults with chronic tinnitus and systematically identify the self-help techniques used.*Design*: Systematic review and application of health psychology taxonomies. Electronic database searches were condu... περισσότερα »

A practical guide to cochlear implantation in adults with long durations of monaural sound deprivation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
A practical guide to cochlear implantation in adults with long durations of monaural sound deprivation: 10.3109/14992027.2016.1166399<br>Isabelle Boisvert Abstract *Objective:* This paper aims to summarize published findings by the authors and integrate these within current literature to support clinical guidelines when choosing an ear for cochlear implantation in adults with long-term monaural sound deprivation. *Study sample:*Four retrospective cohort studies based on data collected in five cochlear implantation centres with adults with bilateral hearing loss who used a single...περισσότερα »

Oxidative stress biomarkers and otoacoustic emissions in humans exposed to styrene and noise

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Oxidative stress biomarkers and otoacoustic emissions in humans exposed to styrene and noise: 10.1080/14992027.2016.1177215<br>R. Sisto Abstract *Objective:* Evaluating the correlation between otoacoustic emission levels, styrene exposure, and oxidative stress biomarkers concentration in styrene-exposed subjects, to investigate the role of oxidative stress in outer hair cell damage. *Design:* Distortion product otoacoustic emissions were measured in the exposed workers and in a control group. Separation between the distortion and reflection otoacoustic components was performed b... περισσότερα »

Developing an assessment approach for perceptual changes to tinnitus sound characteristics for adult cochlear implant recipients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Developing an assessment approach for perceptual changes to tinnitus sound characteristics for adult cochlear implant recipients: 10.3109/14992027.2016.1172391<br>David Greenberg Abstract *Objective:* To investigate the impact of cochlear implantation on tinnitus suppression, characteristics, localization, and duration. *Design*: A cochlear implant (CI) recipient-focused postal questionnaire survey. *Study sample*: The questionnaire was posted, with consent, to 100 adults who had received a unilateral CI at the RNTNEH between 1988 and 1999. All adults spoke English as their firs... περισσότερα »

Velopharyngeal status of vowels produced with and without hard glottal attack in children with repaired cleft palate

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Velopharyngeal status of vowels produced with and without hard glottal attack in children with repaired cleft palate: The objective of this study was to describe velopharyngeal (VP) closure patterns of isolated vowels produced by infants with repaired cleft palate (CP). Nasal ram pressure (NRP) and audio signals were obtained from six infants with repaired CP (four males and two females). Two infants were 12 months of age and four were 18 months of age. All infants were from American-English speaking families without known syndromes. A total number of 95 isolated vowels were anal...περισσότερα »

Measuring contact area in synthetic vocal fold replicas using electrical resistance

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Measuring contact area in synthetic vocal fold replicas using electrical resistance: Synthetic vocal fold replicas are a useful tool for studying human voice production. These replicas are often studied using high-speed imaging, but additional analysis procedures are desired that are lower cost, less data intensive, and more conducive to long-term vibration monitoring. Consequently, this work explores the use of electrical resistance to measure vocal fold contact area across the glottis of a synthetic vocal fold replica. The concept is based on electroglottography (EGG), a clinic... περισσότερα »

Acoustic trajectory corrections to improve mapping of moving sources

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Acoustic trajectory corrections to improve mapping of moving sources: In the context of pass-by experiments, moving-source mapping is classically performed using the extension of conventional beamforming to moving sources: beamforming-MS. The main issue of moving-source mapping is the knowledge of the trajectory of the moving vehicle that contains the sources. This trajectory is mandatory to use the beamforming-MS. Indeed, trajectory errors induce localization artifacts in beamforming results, which can degrade beamforming-MS performance and bias physical interpretations of the l...περισσότερα »

Voiceless nasalization

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
On the presence of voiceless nasalization in apparently effaced Somali Chizigula prenasalized stops: Somali Chizigula (G311; xma; also Mushungulu) is an endangered language spoken in Somalia and by Somali-Bantu refugees abroad. We report on an acoustic and aerodynamic study of N + stop sequences in Somali Chizigula. Our findings illustrate that while the only acoustic cue for the nasal in voiceless prenasalized stops is aspiration of the oral stop, appearing to have undergone total effacement, aerodynamic data show robust nasal airflow prior to the oral stop. Although nasal devoi...περισσότερα »

Underlying mechanism for nasal rustle noise during speech in children with cleft palate

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Underlying mechanism for nasal rustle noise during speech in children with cleft palate: Nasal rustle (AKA Nasal turbulence) occurs as an obligatory nasal air emission in children with cleft palate. It usually occurs as a result of air passing through a partially small velopharyngeal port. As the air moves through this small opening, the air pressure increases. When this pressurized air is released on the nasal side of the opening, it causes nasal secretions on top of the valve to bubble. The hypotheses is that nasal rustle is due to audible bubbling of secretions; so when secret... περισσότερα »

Muscular structure of the human tongue from magnetic resonance image volumes

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Muscular structure of the human tongue from magnetic resonance image volumes: The human tongue has a complex architecture, consistent with its complex roles in eating, speaking, and breathing. Tongue muscle architecture has been depicted in drawings and photographs, but not quantified volumetrically. This study aims to fill that gap by measuring the muscle architecture of the tongue for 14 people captured in high-resolution 3D MRI volumes. The results show the structure, relationships, and variability among the muscles, as well as the effects of age, gender, and weight on muscle v...περισσότερα »

Affricate contrasts in Déline Slavey

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Affricate contrasts in Déline Slavey: Dene or North Slavey is a Dene (Athabaskan) language with nine affricates: /ts, tsʰ, ts’, t∫, t∫ʰ, t∫’, tɬ, tɬʰ, and tɬ’/. This paper provides a first investigation into the acoustics of these sounds using ~2000 tokens from eight speakers from Déline, NT, Canada. Within the lateral series, [tɬ] was found to be realized in a number of ways including [tɬ], [tɬl], [tl], and [tɬɮ], with phonetic voicing to varying degrees in the release. In contrast, [tɬʰ] was generally produced with a brief period of aspiration following the frication portion of t... περισσότερα »

Models and methods for exploring anisotropy and inhomogeneity in vibrating vocal fold tissue

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Models and methods for exploring anisotropy and inhomogeneity in vibrating vocal fold tissue: Synthetic vocal foldmodels have long been used to study features of human voice production that cannot reasonably be studied in vivo. Numerous models have been developed to study different aspects of voice production. Some models have focused, for example, on mimicking geometry or tissue layering while others have been used to study the effect of vibration on live cells. Two aspects of vocal fold structure that have yet to be fully explored are the anisotropic and the inhomogeneous quali... περισσότερα »

Word length is (in part) predicted by phoneme inventory size and syllable structure

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Word length is (in part) predicted by phoneme inventory size and syllable structure: Based on anecdotal data from a few languages, it has been proposed that typical word length in a language is correlated with the size of the phoneme inventory: more phonemes predicts shorter words. This hypothesis has now been examined in some detail using a substantial sample of languages. A standardized text widely employed for phonetic illustrations is used, namely, the fable of “The North Wind and the Sun.” Illustrations published by the IPA and others have been collected for over 100 languag... περισσότερα »

Perceived gender in clear and conversational speech

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Perceived gender in clear and conversational speech: Much of our understanding of gender perception in voice and speech is based on sustained vowels or single words, which eliminates temporal, prosodic, and articulatory cues available in more natural, connected speech. Further, while many studies have examined acoustic and sociolinguistic differences between male and female voices, the relationship between talker speaking style and perception of gender has not yet been explored. Clear speech, adopted by talkers who perceive some barrier to effective communication, is one such speak... περισσότερα »

20Q: Interventional Audiology - Changing the Way We Deliver Care

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
Question 1: Interventional audiology? I'm not too sure exactly what that is? Answer: Well, it can be a lot of different things. In general, when we use the term interventional audiology, we are referring to direct involvement with people who have hearing loss or self-reported difficulties with their hearing. In many instances, it involves changing the way we think about patient care, which often requires looking at patient care from an inter-professional standpoint. Or, looking at different ways to provide services. from #Audiology via xlomafota13 on Inoreader http://ift.tt/21N17... περισσότερα »

20Q: Interventional Audiology - Changing the Way We Deliver Care

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 21 δευτερόλεπτα
Question 1: Interventional audiology? I'm not too sure exactly what that is? Answer: Well, it can be a lot of different things. In general, when we use the term interventional audiology, we are referring to direct involvement with people who have hearing loss or self-reported difficulties with their hearing. In many instances, it involves changing the way we think about patient care, which often requires looking at patient care from an inter-professional standpoint. Or, looking at different ways to provide services. from #Audiology via ola Kala on Inoreader http://ift.tt/21N174F ... περισσότερα »

20Q: Interventional Audiology - Changing the Way We Deliver Care

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 21 δευτερόλεπτα
Question 1: Interventional audiology? I'm not too sure exactly what that is? Answer: Well, it can be a lot of different things. In general, when we use the term interventional audiology, we are referring to direct involvement with people who have hearing loss or self-reported difficulties with their hearing. In many instances, it involves changing the way we think about patient care, which often requires looking at patient care from an inter-professional standpoint. Or, looking at different ways to provide services. from #Audiology via xlomafota13 on Inoreader http://ift.tt/21N17... περισσότερα »

Factors affecting volume change of myocutaneous flaps in oral cancer

Publication date: Available online 8 May 2016 Source:International Journal of Oral and Maxillofacial Surgery Author(s): A. Hiraki, T. Yamamoto, R. Yoshida, M. Nagata, K. Kawahara, Y. Nakagawa, Y. Matsuoka, T. Tanaka, A. Hirosue, D. Fukuma, T. Ikebe, M. Shinohara, H. Nakayama After oral cancer resection with flap reconstruction, the volume of the flap decreases over […]

Factors affecting volume change of myocutaneous flaps in oral cancer

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 26 δευτερόλεπτα
Publication date: Available online 8 May 2016 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): A. Hiraki, T. Yamamoto, R. Yoshida, M. Nagata, K. Kawahara, Y. Nakagawa, Y. Matsuoka, T. Tanaka, A. Hirosue, D. Fukuma, T. Ikebe, M. Shinohara, H. Nakayama After oral cancer resection with flap reconstruction, the volume of the flap decreases over time. The purpose of this study was to estimate the volume change in myocutaneous flaps and to identify the clinical factors associated with this volume decrease. Postoperative computed tomography scans and magnetic res...περισσότερα »

Involvement of Microglial P2Y12 Signaling in Tongue Cancer Pain

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Involvement of Microglial P2Y12 Signaling in Tongue Cancer Pain: To elucidate if microglial P2Y12 receptor (P2Y12R) mechanisms are involved in the trigeminal spinal subnucleus caudalis (Vc; also known as the medullary dorsal horn) in intraoral cancer pain, we developed a rat model of tongue cancer pain. Squamous cell carcinoma (SCC) cells were inoculated into the tongue of rats; sham control rats received the vehicle instead. Nociceptive behavior was measured as the head-withdrawal reflex threshold (HWRT) to mechanical or heat stimulation applied to the tongue under light anesthesi...περισσότερα »

The tensor veli palatini (tensor palatior tensor muscle of the velum palatinum)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
From Wikipedia, the free encyclopedia *Tensor veli palatini muscle* [image: Musculustensorvelipalatini.png] Dissection of the muscles of the palate from behind (tensor veli palatini visible at upper right). [image: Gray783.png] The otic ganglion and its branches (tensor veli palatini visible at center left). Details Origin Medial pterygoid plate of the sphenoid bone (scaphoid fossa) Insertion Palatine aponeurosis Nerve Medial pterygoid of mandibular nerve (V3) Actions Tension of the soft palate Identifiers Latin *Musculus tensor veli palatini* Dorlands /Elsevier *m_22/12551105* TA A05.2.... περισσότερα »

The role of the tensor veli palatini muscle in the development of cleft palate-associated middle ear problems

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
The role of the tensor veli palatini muscle in the development of cleft palate-associated middle ear problems: Abstract ObjectiveOtitis media with effusion is common in infants with an unrepaired cleft palate. Although its prevalence is reduced after cleft surgery, many children continue to suffer from middle ear problems during childhood. While the tensor veli palatini muscle is thought to be involved in middle ear ventilation, evidence about its exact anatomy, function, and role in cleft palate surgery is limited. This study aimed to perform a thorough review of the literature o... περισσότερα »

Orofacial Pain

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
The Neurobiology of Orofacial Pain and Sleep and Their Interactions: This article provides an overview of the neurobiology of orofacial pain as well as the neural processes underlying sleep, with a particular focus on the mechanisms that underlie pain and sleep interactions including sleep disorders. Acute pain is part of a hypervigilance system that alerts the individual to injury or potential injury of tissues. It can also disturb sleep. Disrupted sleep is often associated with chronic pain states, including those that occur in the orofacial region. The article presents many insi... περισσότερα »

Gene Interactions Provide Evidence for Signaling Pathways Involved in Cleft Lip/Palate in Humans

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Gene Interactions Provide Evidence for Signaling Pathways Involved in Cleft Lip/Palate in Humans: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common craniofacial birth defect that has a complex etiology. Genome-wide association studies have recently identified new loci associated with NSCL/P, but these loci have not been analyzed in a Mexican Mestizo population. A complex etiology implies the presence of genetic interactions, but there is little available information regarding this in NSCL/P, and no signaling pathway has been clearly implicated in humans. Her... περισσότερα »

Persistent Orofacial Pain

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Healthcare Cost and Impact of Persistent Orofacial Pain: The DEEP Study Cohort: Few data are available on the healthcare costs of those suffering from persistent orofacial pain (POFP). This cohort and cost analysis study examined the direct costs of POFP from the perspective of the healthcare provider (specifically, the UK National Health Service) in 2012 pounds sterling and sought to identify whether dichotomized (high, IIb to IV; low, 0 to IIa) graded chronic pain scale (GCPS) status is predictive of the total cost of healthcare over the last 6 mo. The healthcare utilization dat... περισσότερα »

Collagen containing polypropylene meshes

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Tissue response to collagen containing polypropylene meshes in an ovine vaginal repair model via Acta Biomaterialia Publication date: Available online 6 May 2016 *Source:*Acta Biomaterialia Author(s): Saeedeh Darzi, Iva Urbankova, Kai Su, Jacinta White, Camden Lo, David Alexander, Jerome A. Werkmeister, Caroline E. Gargett, Jan Deprest Pelvic Organ Prolapse (POP) is the herniation of pelvic organs into the vagina. Despite broad acceptance of mesh use in POP surgical repair, the complication rate is unacceptable. We hypothesized that collagen-containing polypropylene (PP) mesh types cou... περισσότερα »

Multi-biofunction of antimicrobial peptide-immobilized silk fibroin nanofiber membrane

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
: implications for wound healing via Acta Biomaterialia Publication date: Available online 6 May 2016 *Source:*Acta Biomaterialia Author(s): Dae Woong Song, Shin Hwan Kim, Hyung Hwan Kim, Ki Hoon Lee, Chang Seok Ki, Young Hwan Park An antimicrobial peptide motif (Cys-KR12) originating from human cathelicidin peptide (LL37) was immobilized onto electrospun SF nanofiber membranes using EDC/NHS and thiol-maleimide click chemistry to confer the various bioactivities of LL37 onto the membrane for wound care purposes. Surface characterizations revealed that the immobilization density of Cys... περισσότερα »

Masked threshold for noise bands masked by narrower bands of noise: Effects of masker bandwidth and center frequency

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Masked threshold for noise bands masked by narrower bands of noise: Effects of masker bandwidth and center frequency: [image: cm_sbs_024_plain.png] This paper examines how masked thresholds depend on the masker bandwidth and center frequency when the masker has a smaller bandwidth than the signal. The signal bandwidth was equal to the equivalent rectangular bandwidth of the auditory filter and the masker bandwidth was 0.1, 0.35, or 0.6 times the signal bandwidth. The masker and signal were centered at the same frequency of 257, 697, 1538, 3142, or 6930 Hz. Masked thresholds were e... περισσότερα »

Hearing Loss Is the Most Frequent Disability during Childhood

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
In Rural Eastern Ethiopia Hearing Loss Is the Most Frequent Disability during Childhood: A Community Based Survey: by Biftu Geda, Yemane Berhane, Nega Assefa, Alemayehu Worku Background The type and extent of childhood disability in Ethiopia is unknown due to lack of accurate and reliable data. This study tried to assess the magnitude and types of disabilities among children 0–14 years of age in eastern Ethiopia. Methods We conducted a cross-sectional community-based study among households that are under demographic and health surveillance in eastern Ethiopia. The study popula...περισσότερα »

A Cochlear Implant Performance Prognostic Test Based on Electrical Field Interactions Evaluated by eABR (Electrical Auditory Brainstem Responses)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
A Cochlear Implant Performance Prognostic Test Based on Electrical Field Interactions Evaluated by eABR (Electrical Auditory Brainstem Responses): by Nicolas Guevara, Michel Hoen, Eric Truy, Stéphane Gallego Background Cochlear implants (CIs) are neural prostheses that have been used routinely in the clinic over the past 25 years. They allow children who were born profoundly deaf, as well as adults affected by hearing loss for whom conventional hearing aids are insufficient, to attain a functional level of hearing. The “modern” CI (i.e., a multi-electrode implant using sequential ... περισσότερα »

The Health and Well-Being of Older Adults with Dual Sensory Impairment

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
(DSI) in Four Countries: by Dawn M. Guthrie, Anja Declercq, Harriet Finne-Soveri, Brant E. Fries, John P. Hirdes Objectives Dual sensory impairment (DSI) is a combination of vision and hearing impairments that represents a unique disability affecting all aspects of a person’s life. The rates of DSI are expected to increase due to population aging, yet little is known about DSI among older adults (65+). The prevalence of DSI and client characteristics were examined among two groups, namely, older adults receiving home care services or those residing in a long-term care (LTC) fac... περισσότερα »

Trains, transformers, and tinnitus: Case studies in hard-to-detect sounds

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Trains, transformers, and tinnitus: Case studies in hard-to-detect sounds: It’s a phone call many acoustical consultants dread: someone driven crazy by an annoying sound. Sometimes, the source is unknown. Sometimes it’s a nearby industry or antagonistic neighbor. Some sounds are intermittent; some are steady. Some are high frequency; others are low and are described as vibration. Most consultants are greatly relieved if they can hear and measure the sound themselves. But the source can still be elusive, especially if the sound is very faint and if there are multiple potential sou... περισσότερα »

The wide world of noise

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
The wide world of noise: Noise invades all aspects of our lives. The word noise is actually derived from the Latin word “nausea,” with one possible connection being that unpleasant sounds were made by seasick passengers or sailors in ancient times. In modern times, the demand for noise research and consulting has intensified in concert with rising population densities, growing industrialized societies, escalating demands from consumers, and increasingly common standards and legislation related to noise. The Acoustical Society of America Technical Committee on Noise (TC Noise) is c... περισσότερα »

Do caudal blocks cause complications following hypospadias surgery in children?

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1WUtbSN via IFTTT

Impact of caudal block on postoperative complications in children undergoing tubularised incised plate urethroplasty for hypospadias repair: a retrospective cohort study

Summary This study aimed to assess the association between caudal block and postoperative complications after tubularised incised plate urethroplasty. The medical records of 388 paediatric patients who underwent urethroplasty at a tertiary medical centre were analysed retrospectively. Among the 342 patients included, 216 patients received a caudal block and 72 (21.1%) patients suffered surgical complications. […]

Cognitive loading-induced sway alterations are similar in those with chronic ankle instability and uninjured controls

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 8 May 2016 *Source:*Gait &amp; Posture Author(s): Christopher J. Burcal, Erik A. Wikstrom Performing a cognitive task while balancing can result in either increased or decreased sway depending on the nature of the cognitive task, and is commonly used in pathologic populations to evaluate postural performance. A total of 39 participants were recruited into two groups: uninjured controls (n=20, age: 21.9±2.1 years, height: 175.0±11.2cm, mass: 71.3±14.9kg) and chronic ankle instability (n=19, age: 22.1±5.6 years, height: 169.7±7.7cm, mass: 72.9±17.3kg). Par...περισσότερα »

Effects of mid-foot contact area ratio on lower body kinetics/kinematics in sagittal plane during stair descent in women

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 8 May 2016 *Source:*Gait &amp; Posture Author(s): Jinkyu Lee, Yoon No Gregory Hong, Choongsoo S. Shin The mid-foot contact area relative to the total foot contact area can facilitate foot arch structure evaluation. A stair descent motion consistently provides initial fore-foot contact and utilizes the foot arch more actively for energy absorption. The purpose of this study was to compare ankle and knee joint angle, moment, and work in sagittal plane during stair descending between low and high Mid-Foot-Contact-Area (MFCA) ratio group. The twenty-two fema...περισσότερα »

When measuring lead in water, check the temperature

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
Lead contamination in drinking water can be much higher during summer than winter, new research suggests. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1rIR0kE via IFTTT

Boric acid-dependent decrease in regulatory histone H3 acetylation is not mutagenic in yeast

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 1 ώρα
*Candida albicans* is a dimorphic yeast commonly found on human mucosal membranes that switches from yeast to hyphal morphology in response to environmental factors. The change to hyphal growth requires histone H3 modifications by the yeast-specific histone acetyltransferase Rtt109. In addition to its role in morphogenesis, Rtt109-dependent acetylation of histone H3 lysine residues 9 and 56 has regulatory functions during DNA replication and repair. Boric acid (BA) is a broad-spectrum agent that specifically inhibits *C. albicans* hyphal growth, locking the fungus in its harmless ... περισσότερα »

Bioluminescence based system for rapid detection of natural transformation

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 1 ώρα
Horizontal gene transfer plays a significant role in bacterial evolution and holds major clinical importance. Thus, it is vital to understand the mechanisms and kinetics of genetic transformations. Natural transformation is the driving mechanism for horizontal gene transfer in diverse genera of bacteria. Our study introduces a simple and rapid method for the investigation of natural transformation. This highly sensitive system allows the detection of a transformation event directly from bacterial population without any separation step or selection of cells. The system is based on ... περισσότερα »

Poison

Poison: Any substance that can cause severe organ damage or death if ingested, breathed in, or absorbed through the skin. Many substances that normally cause no problems, including water and most vitamins, can be poisonous if taken in excessive quantity. Poison treatment depends on the ‘substance. MedTerms (TM) is the Medical Dictionary of MedicineNet.com. We […]

Mechanisms of lamellar collagen formation in connective tissues

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 2 ώρες
[image: S01429612.gif] Publication date: August 2016 *Source:*Biomaterials, Volume 97 Author(s): Samaneh Ghazanfari, Ali Khademhosseini, Theodoor H. Smit The objective of tissue engineering is to regenerate functional tissues. Engineering functional tissues requires an understanding of the mechanisms that guide the formation and evolution of structure in the extracellular matrix (ECM). In particular, the three-dimensional (3D) collagen fiber arrangement is important as it is the key structural determinant that provides mechanical integrity and biological function. In this review, we ... περισσότερα »

Osteogenic signaling on silk-based matrices

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 2 ώρες
Publication date: August 2016 *Source:*Biomaterials, Volume 97 Author(s): Swati Midha, Sumit Murab, Sourabh Ghosh Bone tissue engineering has mainly focused on generating 3D grafts to repair bone defects. However, the underlying signaling mechanisms responsible for development of such 3D bone equivalents have largely been ignored. Here we describe the crucial aspects of embryonic osteogenesis and bone development including cell sources and general signaling cascades that guide mesenchymal progenitors towards osteogenic lineage. Drawing from the knowledge of developmental biology, we... περισσότερα »

Inosculation and perfusion of pre-vascularized tissue patches containing aligned human microvessels after myocardial infarction

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 2 ώρες
[image: S01429612.gif] Publication date: August 2016 *Source:*Biomaterials, Volume 97 Author(s): Sonja B. Riemenschneider, Donald J. Mattia, Jacqueline S. Wendel, Jeremy A. Schaefer, Lei Ye, Pilar A. Guzman, Robert T. Tranquillo A major goal of tissue engineering is the creation of pre-vascularized tissues that have a high density of organized microvessels that can be rapidly perfused following implantation. This is especially critical for highly metabolic tissues like myocardium, where a thick myocardial engineered tissue would require rapid perfusion within the first several days ...περισσότερα »