Liberal bias and the five-factor model – ERRATUM
Miscellaneous Evan Charney, Behavioral and Brain Sciences, Volume 38, pp e165 Abstract [image: Behavioral and Brain Sciences] [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from Neurology via xlomafota13 on Inoreader http://ift.tt/1Y4grX9 via IFTTT
Endoscopic third ventriculostomy in the treatment of idiopathic normal pressure hydrocephalus: a review study
Abstract Idiopathic normal pressure hydrocephalus is a hydrodynamic disorder whose etiology remains unclear. The diagnosis is mainly clinical and the traditional treatment is cerebrospinal fluid shunt diversion. With the introduction of modern management strategies, endoscopic third ventriculostomy has become a viable alternative to shunting and constitutes a well-established method of treatment for obstructive hydrocephalus. The new hydrodynamic concept of hydrocephalus suggests that endoscopic third ventriculostomy (ETV) may be an effective treatment for communicative hydrocepha... περισσότερα »
Systemic Immune Response to Vaccination on FDG-PET/CT
Systemic Immune Response to Vaccination on FDG-PET/CT: AbstractA patient with newly diagnosed right lung cancer had transient 18F-fluorodeoxyglucose (FDG)-avid left axillary lymph nodes and intense splenic FDG uptake on positron emission tomography (PET)/computed tomography (CT). History revealed that the patient received a left-sided influenza vaccine 2–3 days before the examination. Although inflammatory FDG uptake in ipsilateral axillary nodes is reported, to our knowledge, this is the first report of visualization of the systemic immune response in the spleen related to the inf... περισσότερα »
Human papillomavirus genotypes among women with or without HIV infection: an epidemiological study of Moroccan women from the Souss area
Human papillomavirus genotypes among women with or without HIV infection: an epidemiological study of Moroccan women from the Souss area: Abstract BackgroundData on Human PapillomaVirus (HPV) infection are scarce in Morocco. The objective of the study was to determine the prevalence of HPV and cervical cytology abnormalities in women from the Souss area, Morocco. MethodsTwo hundred and thirty two women who attended the Hassan II hospital (Agadir, Morocco) were recruited in this study. Socio-economic data, sexual activity, reproductive life, history of Pap smear, smoking and HIV ...περισσότερα »
Identification of miR-139-5p as a saliva biomarker for tongue squamous cell carcinoma: a pilot study
Identification of miR-139-5p as a saliva biomarker for tongue squamous cell carcinoma: a pilot study: Abstract BackgroundOf all human oral carcinomas, 41 % are localized to the tongue. Despite considerable improvements in both diagnosis and treatment, tongue squamous cell carcinoma (TSCC) has remained one of the most lethal types of cancer. Here, we aimed at identifying a salivary microRNA (miRNA) expression signature specific for TSCC patients. MethodsTo identify putative diagnostic biomarkers, we compared the miRNA expression profiles of saliva samples from three TSCC patient... περισσότερα »
IGF-binding protein 2 is a candidate target of therapeutic potential in cancer
IGF-binding protein 2 is a candidate target of therapeutic potential in cancer: AbstractInsulin-like growth factor (IGF)-binding protein 2(IGFBP2), a key member of IGF family, has been reported as a notable oncogene in most human epithelium cancers. Increasing evidences suggested that IGFBP2 might be a candidate target of therapuetic potential by regulating key cancer metastasis and invasion-associated signaling networks, but there is still confusion about the mechanism on how IGFBP2 takes part in these processes. In this review, we summarized the current points of view that IGFBP2... περισσότερα »
Upregulation of PTEN suppresses invasion in Tca8113 tongue cancer cells through repression of epithelial–mesenchymal transition (EMT)
Upregulation of PTEN suppresses invasion in Tca8113 tongue cancer cells through repression of epithelial–mesenchymal transition (EMT): AbstractWe previously discovered that the expression of the tumor suppressor phosphatase and tensin homolog (PTEN) was downregulated in the majority patients with tongue squamous cell carcinoma (TSCC). The aim of this study was to investigate the role of PTEN overexpression in the regulation of epithelial–mesenchymal transition (EMT) of the tongue squamous carcinoma cell line Tca8113 as well as explore the underlying mechanism. GV230 (containing the...περισσότερα »
Melphalan-induced vascular toxicity
In search of underlying mechanisms and potential drugs of melphalan-induced vascular toxicity through retinal endothelial cells using bioinformatics approach: AbstractWe aimed to explore molecular mechanism and drug candidates of vascular toxicities associated with melphalan after treating human retinal endothelial cells (RECs). GSE34381 microarray data was firstly downloaded and used to identify the differentially expressed genes (DEGs) in human REC treated with melphalan vs. untreated cells by limma package in R language. The transcription network was constructed based on TRANSFA...περισσότερα »
Comparative analysis of basaloid and conventional squamous cell carcinomas of the esophagus: prognostic relevance of clinicopathological features and protein expression
Comparative analysis of basaloid and conventional squamous cell carcinomas of the esophagus: prognostic relevance of clinicopathological features and protein expression: AbstractBasaloid squamous cell carcinoma (BSCC), a variant of squamous cell carcinoma (SCC), is a rare and aggressive epithelial malignancy which has been reported in only 0.1–11 % of primary esophageal carcinomas. In this study, a comparison of clinicopathological features and protein expression between esophageal BSCC (EBSCC) and conventional esophageal SCC (ESCC) cases from Brazil was performed in order to find ... περισσότερα »
High expression of Naa10p associates with lymph node metastasis and predicts favorable prognosis of oral squamous cell carcinoma
High expression of Naa10p associates with lymph node metastasis and predicts favorable prognosis of oral squamous cell carcinoma: AbstractN-a-Acetyltransferase 10 protein (Naa10p) is a potential prognostic biomarker and a modulator of several types of cancer. Despite the efforts to elucidate the relationship between Naa10p expression and clinical prognosis, little is known about its expression and role in human oral squamous cell carcinoma (OSCC). In this study, we firstly detected the mRNA and protein levels of Naa10p in 10 paired OSCC tissue samples and found Naa10p was frequentl...περισσότερα »
The importance of surgical margins in melanoma
The importance of surgical margins in melanoma: Optimization of margins to minimize morbidity and maximize local control is critical to the success of surgical management of primary melanomas. This article synthesizes the historical perspectives and key clinical trials that have contributed to the evolution of resection margins for melanoma, focusing on the importance of surgical margins in the context of an era of improvements in systemic therapy and greater use of minimally invasive techniques. *J. Surg. Oncol*. © 2015 Wiley Periodicals, Inc.
Superficial soft tissue sarcoma regardless of size or grade
Outcomes of surgical treatment alone in patients with superficial soft tissue sarcoma regardless of size or grade: Background and Objectives Currently, standard treatment of soft tissue sarcoma (STS) is wide local excision and adjuvant radiation, but radiation may be unnecessary in superficial STS. The primary objective is to assess local recurrence rates in patients treated with surgical management alone for superficial STS. Methods A retrospective cancer registry review of patients treated with surgery alone for superficial STS at the Tom Baker Cancer Center (TBCC) was performed. ...περισσότερα »
Dermal melanoma: A report on prognosis, outcomes, and the utility of sentinel lymph node biopsy
Dermal melanoma: A report on prognosis, outcomes, and the utility of sentinel lymph node biopsy: Introduction Historically dermal melanoma (DM) has been labeled as either stage IIIB (in-transit) or stage IV (M1a) disease. We sought to investigate the natural history of DM and the utility and prognostic significance of sentinel lymph node biopsy (SLNB). Methods Patients with DM undergoing SLNB at a single center from 1998 to 2009 were identified. Results Eighty-three patients met criteria, 10 (12%) patients had a positive SLNB. Of those, 5 (50%) recurred (all with distant disease). T... περισσότερα »
Brain metastasis after treatment with intra-operative cesium-131 brachytherapy
Neurocognitive function and quality of life in patients with newly diagnosed brain metastasis after treatment with intra-operative cesium-131 brachytherapy: a prospective trial: AbstractIntraoperative permanent Cesium-131 (Cs-131) brachytherapy can provide a viable alternative to WBRT with excellent response rates and minimal toxicity. This study reports the results of the prospective trial of the impact of intraoperative Cs-131 on neurocognitive function and quality of life (QoL) in patients with resected brain metastases. Between 2010 and 2012, 24 patients with newly diagnosed me...περισσότερα »
Oral Cancer Knowledge and Diagnostic Ability
Oral Cancer Knowledge and Diagnostic Ability Among Dental Students: AbstractThe purpose of this study is to examine factors that influence the diagnostic ability of dental students with regards to oral cancer and oral potentially malignant disorders. Dental students at different levels of study were directly interviewed to examine their oral cancer knowledge and diagnostic ability using a validated and pre-tested survey instrument containing validated clinical images of oral cancer and oral potentially malignant disorders. An oral cancer knowledge scale (0 to 31) was generated from... περισσότερα »
Oral BI 847325 in patients with advanced solid tumors
A phase I study of two dosing schedules of oral BI 847325 in patients with advanced solid tumors: Abstract PurposeThis study determined the safety, maximum tolerated dose (MTD), pharmacokinetics, and preliminary efficacy of BI 847325, an oral dual MEK and Aurora kinase inhibitor, in patients with refractory solid tumors. MethodsThis trial recruited patients with an advanced non-resectable and/or metastatic solid tumor following failure of conventional treatment (NCT01324830; 1287.1). BI 847325 was administered orally, once daily (starting at 6 mg in the first cohort) using two ... περισσότερα »
Periodontal disease severity and cancer risk
Periodontal disease severity and cancer risk in postmenopausal women: the Buffalo OsteoPerio Study: Abstract PurposeFew prospective studies have reported on relationships between objective periodontal disease (PD) measures and cancer risk. This association was examined in 1,337 postmenopausal women participating in the Buffalo OsteoPerio Study. MethodsOral alveolar crestal height (ACH) was measured using oral radiographs. Incident cancers were adjudicated with medical records. Hazard ratios (HRs) and 95 % confidence intervals (CIs) for associations between ACH and incident ca...περισσότερα »
The prognostic value of pretreatment FDG-PET parameters in HPV-associated oropharynx cancer
The prognostic value of pretreatment FDG-PET parameters in HPV-associated oropharynx cancer: Abstract Introduction18Fluorodeoxyglucose positron-emission tomography (FDG-PET) has shown prognostic value in oropharynx cancer but data regarding patients with known human papillomavirus (HPV) status is limited. If prognostic, FDG-PET may play a role in the identification of patients suitable for treatment de-intensification. MethodsPatients with stage III-IVB squamous cell carcinoma of the oropharynx treated with definitive chemoradiation with known HPV status were identified. Clini... περισσότερα »
HPV-Associated Head and Neck Cancer
HPV-Associated Head and Neck Cancer: Over the last two decades, it has been recognized that head and neck cancers, primarily in the oropharynx, can be a distinct entity that is causally related to human papilloma virus (HPV). Fakhry et al. (1) established in 2008 that such tumors have a strikingly better prognosis with improved responsiveness to chemotherapy as well as chemoradiotherapy and favorable survival rates. Since then, new studies have contributed to our increased understanding of this new entity, ranging from a detailed understanding of the genetic fingerprint and risk mo... περισσότερα »
Efficacy of aprepitant for the prevention of chemotherapy-induced nausea and vomiting with a moderately emetogenic chemotherapy regimen: a multicenter, placebo-controlled, double-blind, randomized study in patients with gynecologic cancer receiving paclitaxel and carboplatin
Efficacy of aprepitant for the prevention of chemotherapy-induced nausea and vomiting with a moderately emetogenic chemotherapy regimen: a multicenter, placebo-controlled, double-blind, randomized study in patients with gynecologic cancer receiving paclitaxel and carboplatin: Abstract BackgroundSubstance P contributes to the hypersensitivity reaction (HSR) to paclitaxel in a rat model. Aprepitant acts as an inhibitor of the binding of substance P to the neurokinin-1 receptor and, consequently, may reduce the frequency of paclitaxel-induced HSR. While aprepitant has a prophylactic ...περισσότερα »
Hippocampal dosimetry correlates with the change in neurocognitive function after hippocampal sparing during whole brain radiotherapy: a prospective study
Hippocampal dosimetry correlates with the change in neurocognitive function after hippocampal sparing during whole brain radiotherapy: a prospective study: Abstract BackgroundWhole brain radiotherapy (WBRT) has been the treatment of choice for patients with brain metastases. However, change/decline of neurocognitive functions (NCFs) resulting from impaired hippocampal neurogenesis might occur after WBRT. It is reported that conformal hippocampal sparing would provide the preservation of NCFs. Our study aims to investigate the hippocampal dosimetry and to demonstrate the correlatio...περισσότερα »
Benefits to Speech Perception in Noise From the Binaural Integration of Electric and Acoustic Signals in Simulated Unilateral Deafness.
Benefits to Speech Perception in Noise From the Binaural Integration of Electric and Acoustic Signals in Simulated Unilateral Deafness.: Objectives: This study used vocoder simulations with normal-hearing (NH) listeners to (1) measure their ability to integrate speech information from an NH ear and a simulated cochlear implant (CI), and (2) investigate whether binaural integration is disrupted by a mismatch in the delivery of spectral information between the ears arising from a misalignment in the mapping of frequency to place. Design: Eight NH volunteers participated in the study an...περισσότερα »
The Use of the Kurtosis-Adjusted Cumulative Noise Exposure Metric in Evaluating the Hearing Loss Risk for Complex Noise.
The Use of the Kurtosis-Adjusted Cumulative Noise Exposure Metric in Evaluating the Hearing Loss Risk for Complex Noise.: Objective: To test a kurtosis-adjusted cumulative noise exposure (CNE) metric for use in evaluating the risk of hearing loss among workers exposed to industrial noises. Specifically, to evaluate whether the kurtosis-adjusted CNE (1) provides a better association with observed industrial noise-induced hearing loss, and (2) provides a single metric applicable to both complex (non-Gaussian [non-G]) and continuous or steady state (Gaussian [G]) noise exposures for pr...περισσότερα »
Acoustic Cue Weighting by Adults with Cochlear Implants
Acoustic Cue Weighting by Adults with Cochlear Implants: A Mismatch Negativity Study.: Objectives: Formant rise time (FRT) and amplitude rise time (ART) are acoustic cues that inform phonetic identity. FRT represents the rate of transition of the formant(s) to a steady state, while ART represents the rate at which the sound reaches its peak amplitude. Normal-hearing (NH) native English speakers weight FRT more than ART during the perceptual labeling of the /ba/-/wa/ contrast. This weighting strategy is reflected neurophysiologically in the magnitude of the mismatch negativity (MMN)-... περισσότερα »
Human Immunodeficiency Virus on the Auditory System
A Review of Human Immunodeficiency Virus on the Auditory System: There are an increasing number of large-scale studies on the association between human immunodeficiency virus (HIV) and hearing loss; these studies include both HIV-infected adults from horizontal disease transmission to HIV-infected children from vertical disease transmission in utero. With advances in HIV treatment approaches, this disease has become a chronic health condition rather than a terminal health condition. Based on recent data in this area, mechanisms within the auditory system are at risk based on HIV sta...περισσότερα »
Ménière's Disease: Current and Potential New Objective Measures Using Electrocochleography
Ménière's Disease: Current and Potential New Objective Measures Using Electrocochleography: The characteristic manifestations of Ménière's disease (MD) are mainly subjective, making MD difficult for physicians to diagnose without objective confirmation. A classic electrophysiologic technique for objective diagnosis of MD is electrocochleography (ECochG) to slow stimulus rates. This review will provide information regarding the sensitivity, specificity, and limitations of the conventional click and frequency specific ECochG measures. In addition, the paper will discuss two novel, pro...περισσότερα »
Genetic Hearing Loss
Genetic Hearing Loss: A Comprehensive Review: Hearing loss can be attributed to a variety of inherited and environmental noises (medications, infections, etc.). In recent decades, our improved understanding of genetics, molecular biology, and audiologic pathways has led to the discovery of a variety of Hereditary Hearing Impairments (HHI). HHI can be categorized as syndromic HL and non-syndromic HL, in which HL is associated with other pathophysiological manifestations. Currently, greater than 300 syndromic HLs are recognized, while more than 100 chromosomal loci and 40 genes are at... περισσότερα »
Effects of lateral osteotomy on surgically assisted rapid maxillary expansion
This study aimed to assess the potential effects of two different osteotomy designs of the maxillary lateral wall on dental and skeletal changes after surgically assisted rapid maxillary expansion (SARME). Thirty adult patients were divided into two groups according to the lateral osteotomy design: group 1 (n=16) underwent lateral osteotomy performed in a horizontal straight fashion, and group 2 (n=14) underwent lateral osteotomy performed in parallel to the occlusal plane with a step at the zygomatic buttress. from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1jSdr2... περισσότερα »
Relationship between facial nerve damage and transbuccal trocar placement: an anatomical cohort study
The surgical treatment of ramus and mandibular angle fractures is typically performed by intraoral and transbuccal approaches. As these approaches may result in nerve damage, this anatomical study was performed to establish the relationship between the transbuccal trocar position and the likelihood of inducing facial nerve damage. Twenty dissections of the parotid regions were performed after a simulation of surgical approaches aimed at addressing mandibular condylar and angle fractures. Two trocar tubes, ramic and angular, were inserted and left in position throughout the dissecti...περισσότερα »
Removal of dental implants: review of five different techniques
The aims of this study were to review five different explantation techniques for the removal of failing implants and to propose a practical clinical protocol. During a 10-year period, 95 implants were explanted from 81 patients. Explantation techniques used were the bur–forceps (BF), neo bur–elevator–forceps (ηBEF), trephine drill (TD), high torque wrench (HTW), and scalpel–forceps (SF) techniques. The following parameters were analyzed: indications for explanation, site of implantation, and the type, diameter, and length of the implant removed. from OroFacial Medicine via ola Kal... περισσότερα »
Forward Science and Oral Cancer Foundation partner in video to spread oral cancer awareness, In vivo imaging..
Switch to one email a week Unsubscribe from daily digest Hi Alexandros G. Sfakianakis, This daily digest contains latest stories from the sites you've added on Feedspot. View All New Stories Feedspot review RSS Reader App Oral Cancer News Remove Forward Science and Oral Cancer Foundation partner in video to spread oral cancer awareness by Oral Cancer Foundation News Team, 3 hours ago . Save . Twitter Source: www.DentistryIQ.com Author: DentistryIQ Editors Click here to view Carol Layer's story, told by her daughter Rachel In an effort to increase awaren.. Read... περισσότερα »
Gene expression of a two-component regulatory system associated with sunscreen biosynthesis in the cyanobacterium Nostoc punctiforme ATCC 29133
Long-wavelength ultraviolet radiation (UVA) can damage cells through photo-oxidative stress, leading to harmful photosensitized proteins and pigments in cyanobacteria. To mitigate damage, some cyanobacteria secrete the UVA-absorbing pigment scytonemin into their extracellular sheath. Comparative genomic analyses suggest scytonemin biosynthesis is regulated by the two-component regulatory system (TCRS) proteins encoded by Npun_F1277 and Npun_F1278 in the cyanobacterium *Nostoc punctiforme* ATCC 29133. To understand the dynamics of these genes, their expression was measured followin... περισσότερα »
A bacteriophage journey at the European Medicines Agency
from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1Y14hDT via IFTTT
Additional heparin pre-administration improves cardiac glucose metabolism suppression over low carbohydrate diet alone in 18F-FDG-PET imaging
*Purpose:* Adequate suppression of cardiac glucose metabolism increases the interpretability and diagnostic reliability of 18F-FDG-PET studies performed for cardiac inflammation and infection detection. There are no standardized guidelines, though prolonged fasting (>6 h), carbohydrate-restricted diets, fatty meals and heparin loading have all been proposed. The aim of this study was to compare the three preparatory protocols used in our institution. *Methods:* A total of 150 18F-FDG-PET scans were selected and grouped according to three preparatory protocols (50 consecutive scans... περισσότερα »
Pretargeted immunoPET: Overcoming limitations of space and time
from Medicine via xlomafota13 on Inoreader http://ift.tt/1OV91VN via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OV9tDB via IFTTT
Perfusion Imaging in Clinical Practice: A Multimodality Approach to Tissue Perfusion Analysis
from Medicine via xlomafota13 on Inoreader http://ift.tt/1NR1VMI via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OV9reJ via IFTTT
Pilot Comparison of 68Ga-RM2 PET and 68Ga-PSMA PET in Patients with Biochemically Recurrent Prostate Cancer
Objectives: Glu-NH-CO-NH-Lys-(Ahx)-[68Ga(HBED-CC)] (68Ga-PSMA) is a positron emission tomography (PET) tracer that can detect prostate cancer relapses and metastases by binding to the extracellular domain of PSMA. 68Ga-labeled DOTA-4-amino-1-carboxymethyl-piperidine-D-Phe- Gln-Trp-Ala-Val- Gly-His-Sta-Leu-NH2 (68Ga-RM2) is a synthetic bombesin receptor antagonist that targets gastrin-releasing peptide receptors (GRPr). We present pilot data on the biodistribution of these PET tracers in a small cohort of patients with biochemically recurrent prostate cancer (BCRPC). *Methods:* Sev...περισσότερα »
A Population Based Gaussian Mixture Model Incorporating 18F-FDG-PET and DW-MRI Quantifies Tumor Tissue Classes
The aim of our study was to create a novel Gaussian Mixture Modeling (GMM) pipeline in order to model the complementary information derived from 2-deoxy-2-(18F)-fluoro-D-glucose (18F-FDG)-Positron Emission Tomography (PET) and Diffusion Weighted Magnetic Resonance Imaging (DW-MRI) measurements to separate the tumor microenvironment into relevant tissue compartments and follow the development of these compartments in a longitudinal manner. *Methods:* Serial 18F-FDG-PET and Apparent Diffusion Coefficient (ADC) maps derived from DW-MR images of NCI-H460 xenograft tumors were co-regis... περισσότερα »
Multiparametric analysis of the relationship between tumor hypoxia and perfusion using 18F-FAZA and 15O-H2O PET
18F-fluoroazomycin-arabinoside (18F-FAZA) is a positron emission tomography (PET) tracer of tumor hypoxia. However, as hypoxia often is associated with decreased perfusion, delivery of 18F-FAZA might be compromised, potentially disturbing the association between tissue hypoxia and 18F-FAZA uptake. The aim of this study was to gain insight in the relationship between tumor perfusion and 18F-FAZA uptake. *Methods:* Ten patients diagnosed with advanced non-small cell lung cancer (NSCLC) underwent subsequent dynamic 15 O-H2O and 18F-FAZA PET scans with arterial sampling. Parametric imag... περισσότερα »
A graphene oxide-based FRET sensor for rapid and specific detection of unfolded collagen fragments
Publication date: 15 May 2016 *Source:*Biosensors and Bioelectronics, Volume 79 Author(s): Xiuxia Sun, Jun Fan, Yuping Zhang, Hongli Chen, Yongqing Zhao, Jianxi Xiao The unstructured collagen species plays a critical role in a variety of important biological processes as well as pathological conditions. In order to develop novel diagnosis and therapies for collagen-related diseases, it is essential to construct simple and efficient methods to detect unfolded collagen fragments. We therefore have designed a FITC-labeled collagen mimic triple helical peptide, whose adsorption on the s... περισσότερα »
A novel electrochemical aptasensor for bisphenol A assay based on triple-signaling strategy
[image: alertIcon.gif] Publication date: 15 May 2016 *Source:*Biosensors and Bioelectronics, Volume 79 Author(s): Peng Yu, Yunqing Liu, Xiaohua Zhang, Jiawan Zhou, Erhu Xiong, Xiaoyu Li, Jinhua Chen Based on a triple-signaling strategy, a novel electrochemical aptasensor has been developed for sensitive and selective detection of bisphenol A (BPA). The thiolated ferrocene (Fc)-modified BPA-binding aptamer probe (Fc-P) was immobilized on the gold electrode and then hybridized with the methylene blue (MB)-modified complementary DNA probe (MB-P) to form a rigid double-stranded DNA (ds-... περισσότερα »
High-yield synthesis of strong photoluminescent N-doped carbon nanodots derived from hydrosoluble chitosan for mercury ion sensing via smartphone APP
Publication date: 15 May 2016 *Source:*Biosensors and Bioelectronics, Volume 79 Author(s): Lei Wang, Baoqiang Li, Feng Xu, Xinyao Shi, Demeng Feng, Daqing Wei, Ying Li, Yujie Feng, Yaming Wang, Dechang Jia, Yu Zhou Photoluminescent carbon nanodots (CNDs) have offered considerable potential to be used in biomedical and environmental fields including live cell imaging and heavy metal ion detection due to their superior quantum emission efficiencies, ability to be functionalized using a variety of chemistries and apparent absence of toxicity. However, to date, synthetic yield of CNDs d... περισσότερα »
Diagnosis and Management of Systemic Sclerosis: A Practical Approach
Abstract Systemic sclerosis is a devastating multisystem rheumatologic condition that is characterized by autoimmunity, tissue fibrosis, obliterative vasculopathy and inflammation. Clinical presentation and course of the condition vary greatly, which complicates both diagnosis and corresponding treatment. In this regard, recent advances in disease understanding, both clinically and biochemically, have led to newer classification criteria for systemic sclerosis that are more inclusive than ever before. Still, significant disease modifying therapies do not yet exist for most patients... περισσότερα »
Consensus on Anterior Discluding Stops for OSA Appliances
*(**Keith Thornton, Barry Glassman, John Viviano,* *Jason Tierney, Steve Carstensen,* *Dan Tache, Harry Ball, Kent Smith, Erin Elliott, Les Priemer, Daniel Klauer, Steve Lamberg, Dennis Marangos, Tony Soileau, Christopher Kelly, Shouresh Charkandeh**)* The LinkedIn Discussion Group, *"SleepDisordersDentistry"* has just completed an open discussion on *"**Anterior Discluding Stop Design, What, Why, When, How and Which…* *".* Here is a consensus for all to ponder. *What was asked,* *"**Anterior Discluding Stop Design, some clinicians make only this design and some never make this...περισσότερα »
The Italian Diabetes and Exercise Study 2 (IDES-2): a long-term behavioral intervention for adoption and maintenance of a physically active lifestyle
Background: Physical activity (PA)/exercise have become an integral part of the management of type 2 diabetes mellitus (T2DM). However, current guidelines are difficult to put into action in this population due to a number of barriers, especially the lack of acceptable, feasible, and validated behavioral intervention strategies. The present manuscript reports the rationale, study design and methods, and design considerations of the Italian Diabetes and Exercise Study (IDES)-2, a randomized controlled trial testing the efficacy of a behavior change strategy in increasing total dail... περισσότερα »
Anti-BP180-type mucous membrane pemphigoid immunoglobulin G shows heterogeneity of internalization of BP180/collagen XVII into keratinocyte cytoplasm
Abstract Anti-BP180-type mucous membrane pemphigoid (BP180-MMP) is a rare autoimmune subepidermal blistering disease that targets the C terminus of BP180*/*collagen XVII. Currently, the pathomechanism of BP180-MMP is not well understood. We reported previously that immunoglobulin G (IgG) from patients with bullous pemphigoid (BP) can induce internalization of BP180 via a macropinocytic pathway, which depletes BP180 and weakens epidermal cell–matrix integrity. The purpose of the present study was to elucidate the pathomechanism of BP180-MMP. Immunohistochemistry of biopsy specimens ... περισσότερα »
Development and evaluation of a regression-based model to predict cesium-137 concentration ratios for saltwater fish
[image: S0265931X.gif] Publication date: February 2016 *Source:*Journal of Environmental Radioactivity, Volume 152 Author(s): John E. Pinder, David J. Rowan, Jim T. Smith Data from published studies and World Wide Web sources were combined to develop a regression model to predict 137Cs concentration ratios for saltwater fish. Predictions were developed from 1) numeric trophic levels computed primarily from random resampling of known food items and 2) K concentrations in the saltwater for 65 samplings from 41 different species from both the Atlantic and Pacific Oceans. A number of dif...περισσότερα »
The “omics” of human male infertility: integrating big data in a systems biology approach
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract Spermatogenesis is a complex process in which >2300 genes are temporally and spatially regulated to form a terminally differentiated sperm cell that must maintain the ability to contribute to a totipotent embryo which can successfully differentiate into a healthy individual. This process is dependent on fidelity of the genome, epigenome, transcriptome, and proteome of the spermatogonia, supporting cells, and the resulting sperm cell. Infertility and/or disease risk may increase in the offspring if abnormalities are present. This review highlights the recent advances in ou... περισσότερα »
Mesenchymal signaling in dorsoventral differentiation of palatal epithelium
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract After palatal fusion, the dorsal and ventral epithelia of the palatal shelf differentiate into the nasal and oral mucosa, respectively. The tissue-specific differentiation of palatal epithelia along the dorsal–ventral axis is regulated by the signaling molecules expressed in the underlying mesenchyme. Thus, as in many other epithelial organs, differentiation relies on epithelial–mesenchymal interactions. To screen for region-specific mesenchymal signaling molecules that determine the fate of the palatal epithelia, we employed a laser microdissection (LMD) method. LMD allo... περισσότερα »
Light and electron microscopic studies of the intestinal epithelium in Notoplana humilis (Platyhelminthes, Polycladida): the contribution of mesodermal/gastrodermal neoblasts to intestinal regeneration
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract Some free-living flatworms in the phylum Platyhelminthes possess strong regenerative capability that depends on putative pluripotent stem cells known as neoblasts. These neoblasts are defined based on several criteria, including their proliferative capacity and the presence of cellular components known as chromatoid bodies. Polyclads, which are marine flatworms, have the potential to be a good model system for stem cell research, yet little information is available regarding neoblasts and regeneration. In this study, transmission electron microscopy and immunostaining ana... περισσότερα »
Brain-midgut cross-talk and autocrine metabolastat via the sNPF/CCAP negative feed-back loop in the American cockroach, Periplaneta americana
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract Immunohistochemical reactivities against short neuropeptide F (sNPF-ir) and crustacean cardioactive peptide (CCAP-ir) were detected in both the brain–subesophageal ganglion (Br-SOG) and midgut epithelial cells of the male American cockroach, *Periplaneta americana*. Four weeks of starvation increased the number of sNPF-ir cells and decreased the CCAP-ir cells in the Br-SOG, whereas refeeding reversed these effects. The contents of sNPF in the Br-SOG, midgut and hemolymph titer decreased in response to an injection of CCAP into the hemocoel of normally fed male cockroaches,... περισσότερα »
Acute myocardial infarction does not affect functional characteristics of adipose-derived stem cells in rats, but reduces the number of stem cells in adipose tissue
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract In most pre-clinical animal studies investigating stem cell therapy in acute myocardial infarction (AMI), the administered stem cells are isolated from healthy donors. In clinical practice, however, patients who suffer from AMI will receive autologous cells, for example using adipose-derived stem cells (ASC). During AMI, inflammation is induced and we hypothesized that this might affect characteristics of ASC. To investigate this, ASC were isolated from rat adipose tissue 1 day (1D group, *n* = 5) or 7 days (7D group, *n* = 6) post-AMI, and were compared with ASC from heal... περισσότερα »
Erratum to: Molecular organization and fine structure of the human tectorial membrane: is it replenished?
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
from Cell via ola Kala on Inoreader http://ift.tt/1OU0McF via IFTTT
Increase in the expression of leukocyte elastase inhibitor during wound healing in corneal endothelial cells
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract Tissue injury triggers a complex network of cellular and molecular responses. Although cell migration and proliferation are the most conspicuous, several other responses, such as apoptosis and increased protease activity, are necessary for a proper restitution of the tissue. In this work, we study the leukocyte elastase inhibitor (LEI) expression during wound healing of bovine corneal endothelial monolayers in culture. LEI is a multifunctional protein with anti-protease and anti-apoptotic activity. When properly cleaved, it is transformed into L-DNase II, a pro-apoptotic ... περισσότερα »
Inhibition of differentiation and function of osteoclasts by dimethyl sulfoxide (DMSO)
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract Dimethyl sulfoxide (DMSO) is an FDA-approved organosulfur solvent that is reported to have therapeutic value in osteoarthritis and osteopenia. DMSO is used as a cryoprotectant for the cryopreservation of bone grafts and mesenchymal stem cells which are later used for bone repair. It is also used as a solvent in the preparation of various scaffolds used for bone tissue engineering purposes. DMSO has been reported to inhibit osteoclast formation in vitro but the mechanism involved has remained elusive. We investigated the effect of DMSO on osteoclast differentiation and func... περισσότερα »
Enhancement of trypsin-like enzymes by A23187 ionophore is crucial for sperm penetration through the egg vestment of the giant freshwater prawn
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract We report the presence of trypsin-like enzymes preferring Boc-QAR-MCA substrate in sperm collected from different portions of male reproductive tracts of the giant freshwater prawn, *Macrobrachium rosenbergii* and compare enzyme activities before and after an A23187 calcium ionophore treatment. Fluorogenic enzyme assays revealed that testicular sperm lysates showed high trypsin-like enzyme activity but the activity was relatively low in vas deferens sperm lysates as well as in the live sperm. Upon sperm treatment with A23187, trypsin-like activity was greatly enhanced in d...περισσότερα »
Characterization of miRNA processing machinery in the embryonic chick lung
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract Lung development is a very complex process that relies on the interaction of several signaling pathways that are controlled by precise regulatory mechanisms. Recently, microRNAs (miRNAs), small non-coding regulatory RNAs, have emerged as new players involved in gene expression regulation controlling several biological processes, such as cellular differentiation, apoptosis and organogenesis, in both developmental and disease processes. Failure to correctly express some specific miRNAs or a component of their biosynthetic machinery during embryonic development is disastrous,...περισσότερα »
The role and importance of cofilin in human sperm capacitation and the acrosome reaction
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract The spermatozoon is capable of fertilizing an oocyte only after undergoing several biochemical changes in the female reproductive tract, referred to as capacitation. The capacitated spermatozoon interacts with the egg zona pellucida and undergoes the acrosome reaction, which enables its penetration into the egg and fertilization. Actin dynamics play a major role throughout all these processes. Actin polymerization occurs during capacitation, whereas prior to the acrosome reaction, F-actin must undergo depolymerization. In the present study, we describe the presence of the ... περισσότερα »
Combined effect of ligament stem cells and umbilical-cord-blood-derived CD34+ cells on ligament healing
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Abstract Transplantation of ligament-tissue-derived stem cells has become a promising approach in the repair of injured ligament. Neovascularization plays an important role in ligament healing and remodeling. Recently, human umbilical-cord-blood-derived CD34+ cells have been reported to contribute to neoangiogenesis. Therefore, we performed a series of experiments to test our hypothesis that the combination of medial collateral ligament stem cells (MCL-SCs) and umbilical-cord-blood-derived CD34+ cells has synergistic effects on tendon healing. MCL-SCs and umbilical-cord-blood-deri...περισσότερα »
Μercury and lead toxicity
TEMPOL produced inhibition of MN formation and reduction in apoptotic and necrotic cells from mercury and lead toxicity.: [image: Current Science {focus_keyword} TEMPOL produced inhibition of MN formation and reduction in apoptotic and necrotic cells from mercury and lead toxicity. Current Science] Current Science (00113891) . 1/25/2013, Vol. 104 Issue 2, p224-228. *Modification of cyto- and genotoxicity of mercury and lead by antioxidant on human lymphocytes in vitro.* Roy, Arnab1; Kumar Dey, Subrata1; Saha, Chabita1 1School of Biotechnology and Biological Sciences, West Bengal ... περισσότερα »
Pre-programmed robotic osteotomies for fibula free flap mandible reconstruction: A preclinical investigation
Bony free flap reconstruction of the facial skeleton remains a challenging area of reconstructive surgery. Despite technological advances that have aided planning and execution of these procedures, surgical inaccuracy is not insignificant. One source of error that has not been wholly addressed is that attributable to a human operator. In this study, we investigate the feasibility and accuracy of performing osteotomies robotically in pre-programmed fashion for fibula free flap mandible reconstruction as a method to reduce inaccuracies related to human error. A mandibular defect an... περισσότερα »
Tribute to the “Father” of experimental microsurgery, Professor Sun Lee (1920–2015)
from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1lzIYIn via IFTTT
Shift in interictal relative gamma power as a novel biomarker for drug response in two mouse models of absence epilepsy
Summary Objective Two monogenic mouse models of childhood absence epilepsy, *stargazer* and *tottering*, differ strikingly in their response to *N*-methyl-d-aspartate (NMDA) receptor blockade. We sought to evaluate the change in interictal relative gamma power as a reliable biomarker for this gene-linked antiepileptic drug (AED) response. Methods The effects of AEDs on absolute and relative (to the total) power of frequencies between 2 and 300 Hz were analyzed within the interictal electroencephalogram (EEG) and correlated with antiseizure efficacy in awake behaving *stargazer*,...περισσότερα »
Postoperative Chemoradiation in Patients With Node-positive Esophageal Squamous Cell Carcinoma
Postoperative Chemoradiation in Patients With Node-positive Esophageal Squamous Cell Carcinoma: *Condition*: Esophageal Neoplasms *Interventions*: Drug: Paclitaxel; Drug: Cisplatin; Radiation: Radiation *Sponsor*: Chinese Academy of Medical Sciences ArmsAssigned InterventionsExperimental: Arm A During the Phase I it will administered weekly paclitaxel(dose escalation) and cisplatin with concurrent radiation therapy During the Phase II it will administered weekly paclitaxel(dose according to phase I) and cisplatin with concurrent radiation therapy Drug: Paclitaxel starting... περισσότερα »
Talimogene Laherparepvec With Pembrolizumab for Recurrent Metastatic hnscc
Talimogene Laherparepvec With Pembrolizumab for Recurrent Metastatic Squamous Cell Carcinoma of the Head and Neck: *Condition*: Carcinoma of the Head and Neck *Intervention*: Drug: Talimogene laherparepvec in combination with pembrolizumab *Sponsors*: Amgen; Merck Sharp & Dohme Corp. ArmsAssigned InterventionsExperimental: Phase 1b Talimogene laherparepvec in combination with pembrolizumab Drug: Talimogene laherparepvec in combination with pembrolizumab Talimogene laherparepvec will be administered in combination with pembrolizumab starting on day 1. Talimogene laherparepve... περισσότερα »
Caution Against Overinvestigation of Small Thyroid Nodules
Caution Against Overinvestigation of Small Thyroid Nodules: *In Reply* We would like to thank the radiologists who wrote a letter in response to our recently published article. Their primary concern was that our finding of smaller thyroid nodules (TNs) having a relatively increased likelihood of malignancy regardless of Bethesda classification could be misconstrued by readers and, in so doing, perpetuate the overinvestigation of TN. This concern is indeed valid, as this is a true phenomenon within our field. [image: First page PDF preview]
Caution Against Overinvestigation of Small Thyroid Nodules
Caution Against Overinvestigation of Small Thyroid Nodules: *To the Editor* A recent study by Magister et al aimed to determine whether thyroid nodule size affected fine-needle aspiration biopsy (FNAB) results and determined malignancy rates in each Bethesda class. The authors found that nodules smaller than 2 cm had increased probability of malignancy irrespective of the Bethesda class and stated, “our data would suggest that smaller thyroid nodules, as opposed to larger thyroid nodules, pose a relatively increased risk of malignant disease and should be viewed with caution.” We are... περισσότερα »
Thyroidectomy vs Active Surveillance for Subcentimeter Papillary Thyroid Cancers
Thyroidectomy vs Active Surveillance for Subcentimeter Papillary Thyroid Cancers: This Viewpoint compares efficacy and cost of 2 forms of intervention in treating subcentimeter papillary thyroid cancer—thyroidectomy vs active surveillance. [image: First page PDF preview]
Elimination of Elective Tracheotomy in Mandibular Reconstruction With Microvascular Tissue
Elimination of Elective Tracheotomy in Mandibular Reconstruction With Microvascular Tissue: This medical record review identifies potential factors in successful microvascular mandibular reconstruction without an elective tracheotomy. *Importance* Limited data exist on performing major oral cavity resections and reconstructions without elective tracheotomy. *Objectives* To describe a group of patients who successfully underwent major microvascular mandibular reconstruction without an elective tracheotomy and to perform a literature review to identify commonalities between our g... περισσότερα »
Primidone Therapy for Essential Vocal Tremor
Primidone Therapy for Essential Vocal Tremor: This medical record review evaluates the efficacy of primidone in the treatment of essential vocal tremor. *Importance* Essential vocal tremor is difficult to treat. An effective pharmacologic treatment could allow patients to avoid or decrease the frequency or dosage of botulinum neurotoxin injections. *Objective* To evaluate the efficacy of primidone in the treatment of essential vocal tremor. *Design, Setting, and Participants* Medical records of all patients with a primary or secondary diagnosis of laryngeal spasm or essential t... περισσότερα »
Anterior thigh flap for subtotal glossectomy reconstruction
Free-style free flap: Anterior thigh flap: Report of a case of subtotal glossectomy reconstruction via European Annals of Otorhinolaryngology, Head and Neck Diseases Publication date: Available online 10 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): C. Clerico, O. Dassonville, A. Bozec [image: Postoperative view on Day 10 in propulsion and retropulsion.]
Endoscopic Endonasal Repair of Sphenoid Sinus Cerebrospinal Fluid Leaks
Endoscopic Endonasal Repair of Sphenoid Sinus Cerebrospinal Fluid Leaks: Our Experience: AbstractEndoscopic endonasal approaches are becoming increasingly popular over transcranial approaches for repair of cerebrospinal leak defects. Sphenoid sinus CSF leaks pose a significant challenge and carry the risk of life-threatening intracranial complications. Their management depends upon identifying the leak using imaging techniques followed by intraoperative endoscopic localization. Our experience in the endoscopic endonasal management of sphenoid sinus CSF leaks is reported in this pap... περισσότερα »
Abordaje por fosa media, aplicaciones en lesiones del hueso temporal
Abordaje por fosa media, aplicaciones en lesiones del hueso temporal via Acta Otorrinolaringológica Española Publication date: Available online 10 December 2015 *Source:*Acta Otorrinolaringológica Española Author(s): Iván Domenech Juan, Paula Cruz Toro, Ángela Callejo Castillo, Rafael Moya, Jorge L. Merán Gil, Ricardo Bartel El abordaje por fosa media es una técnica quirúrgica de gran utilidad en la cirugía de base de cráneo lateral. Si bien es cierto, que por sus restringidas indicaciones así como por su complejidad técnica ha tenido una implantación limitada.Presentamos nuestra experi...περισσότερα »
Hyaluronan synthases and hyaluronidases in nasal polyps
Hyaluronan synthases and hyaluronidases in nasal polyps: AbstractNasal polyps (NPs) are benign lesions of nasal and paranasal sinuses mucosa affecting 1–4 % of all adults. Nasal polyposis affects the quality of patient’s life as it causes nasal obstruction, postnasal drainage, purulent nasal discharge, hyposmia or anosmia, chronic sinusitis, facial pain and snoring. Without treatment, the disease can alter the craniofacial skeleton in cases of extended growth of polyps. The development of NPs is caused by the hyperplasia of nasal or paranasal sinuses mucosa, and edema of extracellu...περισσότερα »
Pulsatile tinnitus as the presenting symptom in a patient with posterior reversible encephalopathy syndrome
Pulsatile tinnitus as the presenting symptom in a patient with posterior reversible encephalopathy syndrome: Abstract ObjectivesWe present a case of posterior reversible encephalopathy syndrome (PRES) presenting with pulsatile tinnitus. We highlight the significance of a detailed neurological and cardiovascular assessment including the measurement of blood pressure in patients presenting with pulsatile tinnitus. MethodCase presentation and literature review. ResultsOne patient with undiagnosed PRES, who presented to our ear, nose and throat surgery department with pulsatile... περισσότερα »
Moral considerations in non-EXIT airway management
Moral considerations in non-EXIT airway management: The case report “Management of the critical airway when an EXIT procedure is not an option” has important moral decision-making implications. If intubation was not quickly successful, then significant hypoxic brain injury may have resulted. A full discussion of the moral implications in cases such as this, prior to delivery, is important - both to the family and to the clinicians involved. Our contemporary era is characterised by a pronounced disparity of values and belief systems. An active process for moral decision-making based ... περισσότερα »
AIDS cholangiopathy visualized by single-operator cholangioscopy
from Endocrinology via ola Kala on Inoreader http://ift.tt/1NfrSbJ via IFTTT
Morphological and molecular investigations of the holocephalan elephant fish nephron: the existence of a countercurrent-like configuration and two separate diluting segments in the distal tubule
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 59 δευτερόλεπτα
Abstract In marine cartilaginous fish, reabsorption of filtered urea by the kidney is essential for retaining a large amount of urea in their body. However, the mechanism for urea reabsorption is poorly understood due to the complexity of the kidney. To address this problem, we focused on elephant fish (*Callorhinchus milii*) for which a genome database is available, and conducted molecular mapping of membrane transporters along the different segments of the nephron. Basically, the nephron architecture of elephant fish was similar to that described for elasmobranch nephrons, but so... περισσότερα »
Histochemical analysis of testis specific gene 13 in human normal and malignant tissues
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 59 δευτερόλεπτα
Abstract Testis-specific gene 13 (TSGA13) is abundantly expressed in testis. As previous studies of TSGA13 expression pattern have all been based on mRNA analysis, it is imperative to investigate its actual protein expression. Here, we first examined TSGA13 gene tree and protein homology among species, and found that TSGA13 is relatively well conserved. Next, we detected its protein expression in normal human tissues as well as in a limited number of malignant tumors by immunohistochemistry (IHC). It was demonstrated that, in addition to testis, high expression of TSGA13 could als...περισσότερα »
Co-localization of Gamma-Aminobutyric Acid and Glutamate in Neurons of the Spider Central Nervous System
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 59 δευτερόλεπτα
Abstract Spider sensory neurons with cell bodies close to various sensory organs are innervated by putative efferent axons from the central nervous system (CNS). Light and electronmicroscopic imaging of immunolabeled neurons has demonstrated that neurotransmitters present at peripheral synapses include γ-aminobutyric acid (GABA), glutamate and octopamine. Moreover, electrophysiological studies show that these neurotransmitters modulate the sensitivity of peripheral sensory neurons. Here, we undertook immunocytochemical investigations to characterize GABA and glutamate-immunoreacti... περισσότερα »
Energy Metabolism in Mesenchymal Stem Cells During Osteogenic Differentiation
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 59 δευτερόλεπτα
Stem Cells and Development , Vol. 0, No. 0. from Cell via ola Kala on Inoreader http://ift.tt/1Nfly3T via IFTTT
Association between sleep parameters and cognitive function in drug-naïve children with attention-deficit hyperactivity disorder: a polysomnographic study
• Correlation between sleep and cognition in ADHD patients were present in the study.• REM sleep predicted Conners' Global Index – Parent version in ADHD patients.• Various sleep parameters predicted neurocognitive measures in ADHD patients. from #SleepMedicine via ola Kala on Inoreader http://ift.tt/1QzLAB8 via IFTTT
Consensus on Anterior Discluding Stops for OSA Appliances
*(**Keith Thornton, Barry Glassman, John Viviano,* *Jason Tierney, Steve Carstensen,* *Dan Tache, Harry Ball, Kent Smith, Erin Elliott, Les Priemer, Daniel Klauer, Steve Lamberg, Dennis Marangos, Tony Soileau, Christopher Kelly, Shouresh Charkandeh**)* The LinkedIn Discussion Group, *"SleepDisordersDentistry"* has just completed an open discussion on *"**Anterior Discluding Stop Design, What, Why, When, How and Which…* *".* Here is a consensus for all to ponder. *What was asked,* *"**Anterior Discluding Stop Design, some clinicians make only this design and some never make this...περισσότερα »
