Allergen component analysis as a tool in the diagnosis of occupational allergy
Allergen component analysis as a tool in the diagnosis of occupational allergy: Purpose of review: Rapid developments have been seen in molecular allergy diagnosis, based on the detection and quantification of specific IgE to single allergens. This review summarizes and discusses studies on allergen component analysis as a tool in the diagnosis of occupational allergy. Recent findings: More than 400 agents are identified as sensitizers of occupational asthma, but only very few are characterized on the molecular level and available for routine diagnosis. Baker's asthma is one of the... περισσότερα »
How should occupational anaphylaxis be investigated and managed?
How should occupational anaphylaxis be investigated and managed?: Purpose of review: Anaphylaxis is a systemic allergic reaction that can be life-threatening or fatal and can result from work-related exposures. This review study focuses on the assessment, main triggers, and management of occupational anaphylaxis. Recent findings: Exposed workers can be sensitized through inhalation and skin contact, and the risks increase with penetration of the allergen through the skin. The main eliciting agents of occupational anaphylaxis include stinging insects and animal bites, natural rubber... περισσότερα »
Do chronic workplace irritant exposures cause asthma?
Do chronic workplace irritant exposures cause asthma?: Purpose of review: The present review summarizes the recent literature on the relation between chronic workplace irritant exposures and asthma, focusing on exposures of low to moderate levels. We discuss results from epidemiological surveys, potential biological mechanisms, and needs for further research. These aspects are largely illustrated by studies on exposure to cleaning products. Recent findings: Recent results from nine population-based and workplace-based epidemiological studies, mostly cross-sectional, found an incre...περισσότερα »
Rhinovirus-induced asthma exacerbations and risk populations
Rhinovirus-induced asthma exacerbations and risk populations: Purpose of review: This article discusses recent findings into the mechanisms that determine how viruses trigger asthma exacerbations. Recent findings: Substantial progress has been made in our understanding of the pathogenesis of virus-induced asthma exacerbations. This includes new insights into the role of bacteria, the regulation of interferon responses, and the discovery of innate immune pathways that link viral infections with allergic inflammation. Progress has also been made in elucidating the genetic risk factor... περισσότερα »
Wraparound eyeglasses improve symptoms and quality of life in patients with seasonal allergic rhinoconjunctivitis
Wraparound eyeglasses improve symptoms and quality of life in patients with seasonal allergic rhinoconjunctivitis: Background Allergen avoidance is important for allergic rhinitis management. However, studies evaluating the efficiency of avoidance measures from pollens are lacking. We aimed to investigate the efficiency of wraparound eyeglasses in seasonal allergic rhinoconjunctivitis (SAR). Methods Eligible patients with a diagnosis of SAR (n = 70) rated their symptom scores, filled the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ), and were randomized either to receive ... περισσότερα »
What Are Composite Dental Fillings and Do I Need Them
The post What Are Composite Dental Fillings and Do I Need Them appeared first on Family Dentistry and Cosmetic Surgery Clinic. from #Dental via xlomafota13 on Inoreader http://ift.tt/1QKtLC1 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Ethnicity influences disease characteristics and symptom severity in allergic rhinitis patients in Malaysia
Ethnicity influences disease characteristics and symptom severity in allergic rhinitis patients in Malaysia: Background The number of available reports regarding the influence of ethnicity on clinical features of allergic rhinitis (AR), especially disease severity in tropical climates, is limited. We aimed to compare clinical parameters and disease severity in AR patients of different ethnicities. Methods Malay, Chinese, and Indian AR patients (n = 138) with confirmed sensitivity to *Dermatophagoides pteronyssinus*, *Dematophagoides farinae*, and *Blomia tropicalis* were tested for ... περισσότερα »
Deferiprone and gallium-protoporphyrin against Staphylococcus aureus biofilms
Mind “De GaPP”: in vitro efficacy of deferiprone and gallium-protoporphyrin against Staphylococcus aureus biofilms: Background Biofilms are clusters of bacteria embedded in a protective matrix that frequently cause failure of medical treatments and increase the risk of recurrent infections. In particular, *Staphylococcus aureus* biofilms are associated with a series of chronic and nosocomial infections that are increasingly resistant to antibiotics. This study proposes a novel intervention strategy targeting the essential iron metabolism for bacterial growth, survival and pathogene... περισσότερα »
Connexin gap junction channels and chronic rhinosinusitis
Connexin gap junction channels and chronic rhinosinusitis: Background Gap junction channels are formed by connexin (Cx) proteins. These channels facilitate communication between adjacent cells, and some have been implicated in acute and chronic inflammation. We investigated whether altered connexin expression could be associated with the inflammatory changes of the sinonasal mucosa that characterize chronic rhinosinusitis (CRS). Our aims were first to screen normal sinus mucosa to determine the expression profile of the connexin family of genes, and second to compare the level of e...περισσότερα »
Heat shock proteins and chronic fatigue in primary Sjögrens syndrome
Heat shock proteins and chronic fatigue in primary Sjögrens syndrome: Fatigue occurs frequently in patients with cancer, neurological diseases and chronic inflammatory diseases, but the biological mechanisms that lead to and regulate fatigue are largely unknown. When the innate immune system is activated, heat shock proteins (HSPs) are produced to protect cells. Some extracellular HSPs appear to recognize cellular targets in the brain, and we hypothesize that fatigue may be generated by specific HSPs signalling through neuronal or glial cells in the central nervous system. From a ... περισσότερα »
Application of a central composite design to evaluate the influence of coloring agents in lipsticks formulation
Application of a central composite design to evaluate the influence of coloring agents in lipsticks formulation: Abstract Objective The aim of this study was to evaluate by Central Composite Design the influence of coloring agents in lipstick color, expressed by *L**,* a**,* b** parameters (CIELab system) where *L** indicates lightness, *a** and *b** are the chromaticity coordinates. The *a** indicates color direction from red to green and *b** from yellow to blue. Methods Lipsticks were formulated as described by Dwivedi et al. (2009). The combined effect of three variables (dye, p...περισσότερα »
Vascularized Lymph Node Transfer: A Review of the Current Evidence
Vascularized Lymph Node Transfer: A Review of the Current Evidence: [image: image]Summary: Over the past decade, lymph node transfer has rapidly gained popularity among plastic surgeons for the treatment of chronic lymphedema because of the initial promising results and its unique technical advantages compared with the other reconstructive options. However, its functional mechanism is still a matter of great debate, and some concerning reports have emerged regarding the safety of this procedure in patients with chronic lymphedema. The authors review the literature on the experimenta... περισσότερα »
Payment per Hour
Prospective Analysis of Payment per Hour in Head and Neck Reconstruction: Fiscally Feasible or Futile?: [image: image]Background: The authors assess the fiscal viability of complex head and neck reconstructive surgery by evaluating its financial reimbursement in the setting of resources used. Methods: The authors prospectively assessed provider reimbursement for consecutive patients undergoing head and neck reconstruction. Total care time was determined by adding 15 minutes to the operative time for each postoperative hospital day and each postoperative follow-up appointment within ... περισσότερα »
Clinical Efficacy of a Modified Nagata Method That Retains the Fascia Pedicle of the Mastoid Skin Flap in Auricular Reconstruction of Chinese Microtia Patients
Clinical Efficacy of a Modified Nagata Method That Retains the Fascia Pedicle of the Mastoid Skin Flap in Auricular Reconstruction of Chinese Microtia Patients: [image: image] Abstract Summary: The purpose of this study was to search for an enhanced blood supply in the distal edge of the skin at the mastoid area in total auricular reconstruction. The authors modified the Nagata method by reserving a subcutaneous fascia pedicle (diameter, 3 to 5 mm) at the intersection of the point 11 to 13 mm from the residual ear tragus (or tragus projection) and 8 to 10 mm from the lowest p... περισσότερα »
Deciphering the Sensitivity and Specificity of the Implantable Doppler Probe in Free Flap Monitoring
Deciphering the Sensitivity and Specificity of the Implantable Doppler Probe in Free Flap Monitoring: [image: image] Background: The efficacy of implantable Doppler probes remains an area of considerable debate. This study aims to decipher its sensitivity and specificity for free flap monitoring. Methods: A retrospective review of all free flaps with an implantable Doppler probe was performed between 2000 and 2012. Results: A Cook-Swartz implantable Doppler probe was used in 439 patients (head and neck, n = 364; breast, n = 53; extremity, n = 22), and demonstrated equivalent sensi...περισσότερα »
Computer-Assisted Surgery for Segmental Mandibular Reconstruction with the Osteoseptocutaneous Fibula Flap: Can We Instigate Ideological and Technological Reforms?
Computer-Assisted Surgery for Segmental Mandibular Reconstruction with the Osteoseptocutaneous Fibula Flap: Can We Instigate Ideological and Technological Reforms?: [image: image]Summary: Virtual surgical planning and computer-aided design and computer-aided modeling are promising technologies with a growing trend in contemporary head and neck reconstruction. Segmental mandibular reconstruction with the osteoseptocutaneous fibula flap is one of the fields in which these technologies are increasingly used. Perceived benefits are increased surgical precision, improved operative effici...περισσότερα »
Mutation Screening of Candidate Genes in Patients with Nonsyndromic Sagittal Craniosynostosis
Mutation Screening of Candidate Genes in Patients with Nonsyndromic Sagittal Craniosynostosis: [image: image]Background: Craniosynostosis is a condition that includes the premature fusion of one or multiple cranial sutures. Among various craniosynostosis forms, sagittal nonsyndromic craniosynostosis is the most prevalent. Although different gene mutations have been identified in some craniosynostosis syndromes, the cause of sagittal nonsyndromic craniosynostosis remains largely unknown. Methods: To screen for candidate genes for sagittal nonsyndromic craniosynostosis, the authors se... περισσότερα »
Lambdoid Craniosynostosis: The Relationship with Chiari Deformations and an Analysis of Surgical Outcomes
Lambdoid Craniosynostosis: The Relationship with Chiari Deformations and an Analysis of Surgical Outcomes: [image: image] Background: A relationship between lambdoid craniosynostosis and Chiari deformations has been suggested, but the true extent of this association remains uncertain. The authors reviewed a single center’s experience treating lambdoid synostosis to further elucidate this relationship, examine surgical outcomes, and identify associations that might impact future treatments. Methods: A retrospective chart review was performed of all patients treated for lambdoid cra...περισσότερα »
Surgeon’s and Caregivers’ Appraisals of Primary Cleft Lip Treatment with and without Nasoalveolar Molding: A Prospective Multicenter Pilot Study
Surgeon’s and Caregivers’ Appraisals of Primary Cleft Lip Treatment with and without Nasoalveolar Molding: A Prospective Multicenter Pilot Study: [image: image] Background: Despite the increasing use of nasoalveolar molding in early cleft treatment, questions remain about its effectiveness. This study examines clinician and caregiver appraisals of primary cleft lip and nasal reconstruction with and without nasoalveolar molding in a nonrandomized, prospective, multicenter study. Methods: Participants were 110 infants with cleft lip/palate (62 treated with and 48 treated without naso... περισσότερα »
Outcomes of Cleft Palate Repair in Patients with Pierre Robin Sequence: A Matched Case-Control Study
Outcomes of Cleft Palate Repair in Patients with Pierre Robin Sequence: A Matched Case-Control Study: [image: image]Background: Pierre Robin sequence results from a cascade of events that occur during embryologic development and frequently presents with cleft palate. Some studies have shown speech outcomes to be worse in patients with Pierre Robin sequence after cleft palate repair. Methods: A cohort of Pierre Robin sequence patients who all required an airway intervention and nasogastric feeding in the neonatal period were identified and speech outcomes assessed at 5 years of age. ... περισσότερα »
The Architecture of Fat Grafting: What Lies beneath the Surface
The Architecture of Fat Grafting: What Lies beneath the Surface: [image: image]Background: Fat grafting is a powerful procedure limited by unpredictable volume loss. Grafted tissue survives via plasmatic imbibition until neovascularization occurs; therefore, fat that is deposited more than 0.2 cm from capillaries will undergo central necrosis. This study aims to determine the architecture of fat deposits within the recipient bed following fat grafting. Methods: Fat was harvested by liposuction and stained with methylene blue. Stained fat was grafted into 4 × 4 × 2-cm sections of pan... περισσότερα »
Plastic Surgery Applications Using Three-Dimensional Planning and Computer-Assisted Design and Manufacturing
Plastic Surgery Applications Using Three-Dimensional Planning and Computer-Assisted Design and Manufacturing: [image: image]Summary: Three-dimensional analysis and planning is a powerful tool in plastic and reconstructive surgery, enabling improved diagnosis, patient education and communication, and intraoperative transfer to achieve the best possible results. Three-dimensional planning can increase efficiency and accuracy, and entails five core components: (1) analysis, (2) planning, (3) virtual surgery, (4) three-dimensional printing, and (5) comparison of planned to actual result... περισσότερα »
A Z-Plasty Modification to the Moberg Flap for Increased Advancement and Decreased Morbidity
Cadaveric Study of a Z-Plasty Modification to the Moberg Flap for Increased Advancement and Decreased Morbidity: [image: image] Background: The Moberg advancement flap is a well-established tool to provide sensate, vascularized tissue for thumb reconstruction. Modifications providing additional length have been described, but no studies have examined how much additional advancement can be achieved consistently, and at what cost. The authors hypothesized that Z-plasty modification at the base of the Moberg flap would allow additional advancement compared with the traditional techniq...περισσότερα »
Antimicrobial activity of conventional and plant-extract disinfectant solutions on microbial biofilms on a maxillofacial polymer surface
Publication date: Available online 26 February 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Aimée Maria Guiotti, Bruno Guandalini Cunha, Marcela Borghi Paulini, Marcelo Coelho Goiato, Daniela Micheline dos Santos, Cristiane Duque, Karina Sampaio Caiaffa, Daniela Atili Brandini, Derly Tescaro Narciso de Oliveira, Natália Seron Brizzotti, Margarete Teresa Gottardo de Almeida Statement of problemDentists often note problems with infection in patients with maxillofacial prostheses. Conventional disinfection protocols are not always effective and may alter the properties ... περισσότερα »
Pull-out retentive strength of fiber posts cemented at different times in canals obturated with a eugenol-based sealer
Publication date: Available online 26 February 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Khalil Aleisa, Ziad Nawaf AL-Dwairi, Sara A. Alsubait, Steven M. Morgano Statement of problemCurrently, no standard luting protocol exists for fiber posts. In addition, no agreement has been reached on the time interval between canal obturation and post space preparation and cementation.PurposeThe purpose of this in vitro study was to evaluate the retention of fiber posts cemented with 3 different types of cement: Paracore, Variolink II, and RelyX Unicem cement after 24 hours ... περισσότερα »
Body Contouring
Body Contouring: [image: image]Learning Objectives: After reading this article, the participant should be able to: 1. Provide a careful preoperative evaluation. 2. Understand the relevant anatomy. 3. Appreciate and apply the range of procedures that can be applied to address an individual patient’s goals. 4. Focus on patient safety and avoiding complications. Summary: Body contouring has advanced significantly over the past decade, fueled by the increased number of massive weight loss patients and the advent of new fat-reduction technologies. This has impacted both the number of ca... περισσότερα »
3,4-Methylenedioxy-β-Nitrostyrene Ameliorates Experimental Burn Wound Progression by Inhibiting the NLRP3 Inflammasome Activation
3,4-Methylenedioxy-β-Nitrostyrene Ameliorates Experimental Burn Wound Progression by Inhibiting the NLRP3 Inflammasome Activation: [image: image] Background: Burn wound progression remains a challenging problem in the clinic. Secondary tissue damage caused by unlimited inflammatory response is considered to be one of the key factors contributing to this clinical problem. Nucleotide-binding oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome has recently been found to play important roles in immune activation and the inflammatory response afte... περισσότερα »
Unilateral Cleft Lip Repair Using the Anatomical Subunit Approximation: Modifications and Analysis of Early Results in 100 Consecutive Cases
*Unilateral Cleft Lip Repair Using the Anatomical Subunit Approximation: Modifications and Analysis of Early Results in 100 Consecutive Cases: * Ibrahim, Abdulrasheed F.W.A.C.S.; Asuku, Malachy Eneye F.W.A.C.S. *Free Access* *Article Outline* *[image: Collapse Box]*Author Information *Division of Plastic and Reconstructive Surgery, Ahmadu Bello University Teaching Hospital, Shika-Zaria, Kaduna State, Nigeria* *Correspondence to Dr. Ibrahim, Division of Plastic and Reconstructive Surgery, Ahmadu Bello University Teaching Hospital, PMB 06 Shika-Zaria, Kaduna State 810001, Nigeria,sh... περισσότερα »
Opposite Effects of Soluble Factors Secreted by Adipose Tissue on Proliferating and Quiescent Osteosarcoma Cells
Opposite Effects of Soluble Factors Secreted by Adipose Tissue on Proliferating and Quiescent Osteosarcoma Cells: [image: image] Background: Autologous adipose tissue transfer may be performed for aesthetic needs following resection of osteosarcoma, the most frequent primary malignant tumor of bone, excluding myeloma. The safety of autologous adipose tissue transfer regarding the potential risk of cancer recurrence must be addressed. Methods: Adipose tissue injection was tested in a human osteosarcoma preclinical model induced by MNNG-HOS cells. Culture media without growth factor...περισσότερα »
Platelet-Rich Plasma Influences Expansion and Paracrine Function of Adipose-Derived Stromal Cells in a Dose-Dependent Fashion
Platelet-Rich Plasma Influences Expansion and Paracrine Function of Adipose-Derived Stromal Cells in a Dose-Dependent Fashion: [image: image]Background: Lipofilling is a treatment modality to restore tissue volume. Both platelet-rich plasma and adipose-derived stromal cells have been reported to augment the efficacy of lipofilling, yet results are not conclusive. The authors hypothesized that the variation reported in literature is caused by a dose-dependent influence of platelet-rich plasma on adipose-derived stromal cells. Methods: Whole blood (n = 3) was used to generate platelet... περισσότερα »
Optimizing Biomaterials for Tissue Engineering Human Bone Using Mesenchymal Stem Cells
Optimizing Biomaterials for Tissue Engineering Human Bone Using Mesenchymal Stem Cells: [image: image]Background: Adequate biomaterials for tissue engineering bone and replacement of bone in clinical settings are still being developed. Previously, the combination of mesenchymal stem cells in hydrogels and calcium-based biomaterials in both in vitro and in vivo experiments has shown promising results. However, results may be optimized by careful selection of the material combination. Methods: β-Tricalcium phosphate scaffolds were three-dimensionally printed with five different hydrog...περισσότερα »
Does Separating the Stromal Vascular Fraction Improve Facial Fat Retention?
*Does Separating the Stromal Vascular Fraction Improve Facial Fat Retention?: * Swanson, Eric M.D. *Free Access* *Article Outline* *[image: Collapse Box]*Author Information *Swanson Center, 11413 Ash Street, Leawood, Kan. 66211, eswanson@swansoncenter.com* *Back to Top | Article Outline* Sir: *Schendel1 concludes that separating the stromal vascular fraction (SVF) and injecting it along with the lipoaspirate improves the results of facial fat injection. The author claims that his study is the first to document facial fat enrichment using three-dimensional measurements. A draft of...περισσότερα »
Learner Perspectives of a Surgical Educators Faculty Development Program Regarding Value and Effectiveness: A Qualitative Study
Learner Perspectives of a Surgical Educators Faculty Development Program Regarding Value and Effectiveness: A Qualitative Study: [image: image]Background: The BaylorScott & White Health Division of Plastic Surgery began a faculty development program designed to train clinicians to be better educators. The program consisted of presession reading, 11 small group didactic sessions, and individually chosen educational projects. Cross-discipline collaboration was pursued by enrolling faculty and students from diverse departments. Department chair permission was required for participation.... περισσότερα »
Topical Application of Arnica and Mucopolysaccharide Polysulfate Attenuates Periorbital Edema and Ecchymosis in Open Rhinoplasty: A Randomized Controlled Clinical Study
Topical Application of Arnica and Mucopolysaccharide Polysulfate Attenuates Periorbital Edema and Ecchymosis in Open Rhinoplasty: A Randomized Controlled Clinical Study: [image: image]Background: The purpose of this study was to investigate the effects of local arnica and mucopolysaccharide polysulfate treatment on the regression of postoperative edema and ecchymosis in patients who have undergone open technique rhinoplasty. Method: One hundred eight patients were included in the study. Participants were randomized into three groups, all of whom had undergone rhinoplasty. Group 1 (n... περισσότερα »
Deaths Caused by Gluteal Lipoinjection: What Are We Doing Wrong?
Deaths Caused by Gluteal Lipoinjection: What Are We Doing Wrong?: [image: image] No abstract available
Adipofascial Flap in the Recipient Incision Site for Coverage of Vascular Pedicle in Free Tissue Transfer
Adipofascial Flap in the Recipient Incision Site for Coverage of Vascular Pedicle in Free Tissue Transfer: [image: image] Summary: The recipient incision adipofascial flap offers a simple approach to address a tight skin closure over a vascular pedicle. This technique is not just fast and easy to perform but also adds little to no morbidity, removing a potential source of flap failure.
Current Thoughts on Fat Grafting: Using the Evidence to Determine Fact or Fiction
Current Thoughts on Fat Grafting: Using the Evidence to Determine Fact or Fiction: [image: image]Background: Autologous fat grafting is an increasingly popular procedure used for facial rejuvenation and body contouring. The purpose of this article is to perform an evidence-based review to determine fact from fiction for the hot topics in autologous fat grafting. Methods: A comprehensive literature search was performed. The following key words were then searched: “fat grafting,” “autologous fat grafting,” “autologous fat transfer,” “lipotransfer,” “liposculping,” and “lipofilling.” ... περισσότερα »
Global Aesthetics Consensus: Botulinum Toxin Type A—Evidence-Based Review, Emerging Concepts, and Consensus Recommendations for Aesthetic Use, Including Updates on Complications
Global Aesthetics Consensus: Botulinum Toxin Type A—Evidence-Based Review, Emerging Concepts, and Consensus Recommendations for Aesthetic Use, Including Updates on Complications: [image: image]Background: Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide, with a high rate of efficacy and patient satisfaction. Methods: A multinational, multidisciplinary group of plastic surgeons and dermatologists convened the Global Aesthetics Consensus Group to develop updated consensus recommendations with a worldwide perspective for botulinum toxin and ... περισσότερα »
A Split-Face Study of the Effects of a Stabilized Hyaluronic Acid–Based Gel of Nonanimal Origin for Facial Skin Rejuvenation Using a Stamp-Type Multineedle Injector: A Randomized Clinical Trial
A Split-Face Study of the Effects of a Stabilized Hyaluronic Acid–Based Gel of Nonanimal Origin for Facial Skin Rejuvenation Using a Stamp-Type Multineedle Injector: A Randomized Clinical Trial: [image: image]Background: The mid-dermal injection of stabilized hyaluronic acid–based gel of nonanimal origin has been shown to be an effective method for skin rejuvenation. The previous manual technique, using a prefilled syringe, made it difficult to precisely control the injection into the mid-dermal layers and to achieve an even distribution of gel across the area. This single-center, e... περισσότερα »
Aggressive Overlapping Intravelar Veloplasty: The Unanswered Questions
*Aggressive Overlapping Intravelar Veloplasty: The Unanswered Questions: * Sharma, Ramesh Kumar M.S., M.Ch.(Plast. Surg.) *Free Access* *Article Outline* *[image: Collapse Box]*Author Information *Department of Plastic Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India, drsharmark@yahoo.com* *Back to Top | Article Outline* Sir: *We have read the article “Progressive Tightening of the Levator Veli Palatini Muscle Improves Velopharyngeal Dysfunction in Early Outcomes of Primary Palatoplasty” by Nguyen et al.1 with great interest and would like... περισσότερα »
Antimicrobial activity of conventional and plant-extract disinfectant solutions on microbial biofilms on a maxillofacial polymer surface
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Publication date: Available online 26 February 2016 Source:The Journal of Prosthetic Dentistry Author(s): Aimée Maria Guiotti, Bruno Guandalini Cunha, Marcela Borghi Paulini, Marcelo Coelho Goiato, Daniela Micheline dos Santos, Cristiane Duque, Karina Sampaio Caiaffa, Daniela Atili Brandini, Derly Tescaro Narciso de Oliveira, Natália Seron Brizzotti, Margarete Teresa Gottardo de Almeida Statement of problemDentists often note […]
Pull-out retentive strength of fiber posts cemented at different times in canals obturated with a eugenol-based sealer
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Publication date: Available online 26 February 2016 Source:The Journal of Prosthetic Dentistry Author(s): Khalil Aleisa, Ziad Nawaf AL-Dwairi, Sara A. Alsubait, Steven M. Morgano Statement of problemCurrently, no standard luting protocol exists for fiber posts. In addition, no agreement has been reached on the time interval between canal obturation and post space preparation and cementation.PurposeThe […]
Technique for identifying keratinized gingival tissue and soft tissue morphology on 3-dimensional implan t-planning software images
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Publication date: Available online 26 February 2016 Source:The Journal of Prosthetic Dentistry Author(s): Toshio Kaku, Yoichiro Ogino, Yasuyuki Matsushita, Kiyoshi Koyano Preoperative 3-dimensional (3D) planning using cone beam computed tomography (CBCT) and 3D implant-planning software is used routinely for implant placement. However, despite its importance in planning surgical technique (conventional or flapless surgery) and prognosis, […]
Effect of sealant agents on the color stability and surface roughness of nanohybrid composite resins
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Publication date: Available online 26 February 2016 Source:The Journal of Prosthetic Dentistry Author(s): Doğu Ömür Dede, Onur Şahin, Aysegül Koroglu, Burak Yilmaz Statement of problemThe effect of sealant agents on the surface roughness and color stability of nanohybrid composite resins is unknown.PurposeThe purpose of this in vitro study was to evaluate the effect of sealant […]
Flexible endoscopic evaluation of swallowing (FEES) for neurogenic dysphagia: training curriculum of the German Society of Neurology and the German stroke society.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Flexible endoscopic evaluation of swallowing (FEES) for neurogenic dysphagia: training curriculum of the German Society of Neurology and the German stroke society. BMC Med Educ. 2016;16(1):70 Authors: Dziewas R, Glahn J, Helfer C, Ickenstein G, Keller J, Ledl C, Lindner-Pfleghar B, G Nabavi D, Prosiegel M, Riecker A, Lapa S, Stanschus S, Warnecke T, Busse […]
A Distributed Network for Social Cognition Enriched for Oxytocin Receptors.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
A Distributed Network for Social Cognition Enriched for Oxytocin Receptors. J Neurosci. 2016 Feb 24;36(8):2517-35 Authors: Mitre M, Marlin BJ, Schiavo JK, Morina E, Norden SE, Hackett TA, Aoki CJ, Chao MV, Froemke RC Abstract UNLABELLED: Oxytocin is a neuropeptide important for social behaviors such as maternal care and parent-infant bonding. It is believed that […]
Vestibular Assessment and Rehabilitation: Ten-Year Survey Trends of Audiologists’ Opinions and Practice.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Related Articles Vestibular Assessment and Rehabilitation: Ten-Year Survey Trends of Audiologists’ Opinions and Practice. J Am Acad Audiol. 2016 Feb;27(2):126-40 Authors: Nelson MD, Akin FW, Riska KM, Andresen K, Mondelli SS Abstract BACKGROUND: The past decade has yielded changes in the education and training of audiologists and technological advancements that have become widely available for […]
Relevance of radiobiological concepts in radionuclide therapy of cancer
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
10.3109/09553002.2016.1144944<br>Chandan Kumar from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1oMsMVX via IFTTT
The Effect of Metformin on Hypothalamic-Pituitary-Thyroid Axis Activity in Women with Interferon-Induced Hypothyroidism: A Pilot Study
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Exp Clin Endocrinol Diabetes 2016; 124: 71-76 DOI: 10.1055/s-0042-101163 Background: One of the most frequent adverse effects of interferon-α therapy is thyroiditis. Metformin was found to improve insulin sensitivity in hepatitis C patients, as well as to reduce elevated thyrotropin levels in patients with hypothyroidism. The aim of this study was to investigate the effect […]
Issue Information
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1QKhQEj via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Lidocaine-Containing Monophasic Hyaluronic Acid Filler for Nasolabial Folds
*A Randomized Clinical Trial to Evaluate the Efficacy and Safety of Lidocaine-Containing Monophasic Hyaluronic Acid Filler for Nasolabial Folds: * *Background: Hyaluronic acid dermal fillers are most frequently used for unwanted wrinkles. Recently, lidocaine has been incorporated into hyaluronic acid fillers to reduce injection discomfort. Methods: A randomized, multicenter, double-blind, intraindividual trial was designed to compare a new lidocaine-containing monophasic hyaluronic acid filler (Neuramis Deep Lidocaine) with a lidocaine-containing biphasic hyaluronic acid fille... περισσότερα »
The Future of Plastic Surgery Resident Education
The Future of Plastic Surgery Resident Education: [image: image]Summary: The challenge of the current graduate medical education environment requires in plastic surgery acceptance of those contemporary pressures that cannot be substantially modified and address of those that can be successfully met. To do so implies an examination of conference didactics, intraoperative teaching, and a valid assessment of resident performance.
Cerebral Processing of Emotionally Loaded Acoustic Signals by Tinnitus Patients
Cerebral Processing of Emotionally Loaded Acoustic Signals by Tinnitus Patients: This exploratory study determined the activation pattern in nonauditory brain areas in response to acoustic, emotionally positive, negative or neutral stimuli presented to tinnitus patients and control subjects. Ten patients with chronic tinnitus and without measurable hearing loss and 13 matched control subjects were included in the study and subjected to fMRI with a 1.5-tesla scanner. During the scanning procedure, acoustic stimuli of different emotional value were presented to the subjects. Statistic... περισσότερα »
Higher prevalence of autoimmune diseases and longer spells of vertigo in patients affected with familial Ménière's disease: A clinical comparison of familial and sporadic Ménière's disease.
[image: http:--pubs.asha.org-images-b_pubmed_ful] Authors: Hietikko E, Sorri M, Männikkö M, Kotimäki J Abstract PURPOSE This study compared clinical features, predisposing factors, and concomitant diseases between sporadic and familial Ménière's disease (MD). METHOD Retrospective chart review and postal questionnaire were used. Participants were 250 definite patients with MD (sporadic, n =149; familial, n = 101) who fulfilled the American Academy of Otorhinolaryngology-Head and Neck Surgery (1995) criteria. RESULTS On average, familial patients were affected 5.6 years earlier than... περισσότερα »
Current status of laparoscopic transhiatal esophagectomy for esophageal cancer patients: a systematic review of the literature
Current status of laparoscopic transhiatal esophagectomy for esophageal cancer patients: a systematic review of the literature: Summary Minimally invasive techniques in transhiatal esophagectomy (THE) were introduced to reduce morbidity and enhance postoperative recovery. Aim of this study was to systematically review the current status and possible beneficial effects of the minimally invasive approach in THE. A systematic search was performed in PubMed, the Cochrane Library, and Embase to identify English articles published on laparoscopic THE. Comparative cohort studies were incl...περισσότερα »
Variation in palliative care of esophageal cancer in clinical practice: factors associated with treatment decisions
Variation in palliative care of esophageal cancer in clinical practice: factors associated with treatment decisions: Summary Various treatments are available for the palliation of esophageal cancer, but the optimal therapeutic approach is unclear. This study aimed to assess the palliative treatment modalities used in patients with inoperable esophageal cancer and to identify factors associated with treatment decisions. A population-based, retrospective cohort study was conducted using data from the nationwide Netherlands Cancer Registry and medical records of seven participating ho... περισσότερα »
Management and outcome of cervical versus intrathoracic manifestation of cervical anastomotic leakage after transthoracic esophagectomy for cancer
Management and outcome of cervical versus intrathoracic manifestation of cervical anastomotic leakage after transthoracic esophagectomy for cancer: Summary The aim of this study was to evaluate management strategies and related outcomes for cervical versus intrathoracic manifestation of cervical anastomotic leakage after transthoracic esophagectomy for cancer with gastric conduit reconstruction. Patients with esophageal cancer undergoing transthoracic esophagectomy with cervical anastomosis from October 2003 to December 2014 were identified from a prospectively acquired database. M...περισσότερα »
Comparison of neoadjuvant chemotherapy versus upfront surgery with or without chemotherapy for patients with clinical stage III esophageal squamous cell carcinoma
Comparison of neoadjuvant chemotherapy versus upfront surgery with or without chemotherapy for patients with clinical stage III esophageal squamous cell carcinoma: Summary Neoadjuvant chemotherapy (NAC) and chemoradiotherapy have been shown to extend postoperative survival, and preoperative therapy followed by esophagectomy has become the standard treatment worldwide for patients with esophageal squamous cell carcinoma (ESCC). The Japan Clinical Oncology Group 9907 study showed that NAC significantly extended survival in advanced ESCC, but the survival benefit for patients with cli...περισσότερα »
“Green” Proteomics: An Environmentally Friendly Protocol Applied to Panax Ginseng
[image: shutterstock_725989271.jpg] Researchers interested in drug discovery and development explore herbal medicines for novel bioactive compounds. One such medicinal supplement is Panax ginseng, whose saponins, or ginsenosides, have been developed into drugs for the treatment of conditions like coronary heart disease, diabetes and chronic hepatitis.1 However, conventional approaches based on phytochemical isolation tend to be inefficient and Read the rest of this article The post "Green" Proteomics: An Environmentally Friendly Protocol Applied to Panax Ginseng appeared first on...περισσότερα »
Preoperative functional status is not associated with postoperative surgical complications in low risk patients undergoing esophagectomty
Preoperative functional status is not associated with postoperative surgical complications in low risk patients undergoing esophagectomty: Summary Preoperative functional status is a risk factor for developing postoperative complications (POC) in major abdominal and thoracic surgery, but this has hardly been evaluated in esophageal cancer patients undergoing esophagectomy. The aim of this prospective cohort study was to determine if preoperative functional status in esophageal cancer patients is associated with POC. From March 2012 to October 2014, esophageal cancer patients schedu...περισσότερα »
Updated incidence rates and risk factors of esophageal cancer in Nan'ao Island, a coastal high-risk area in southern China
Updated incidence rates and risk factors of esophageal cancer in Nan'ao Island, a coastal high-risk area in southern China: Summary Esophageal cancer (EC) is one of the most common cancers in China. The purpose of this study was to investigate the updated incidence rates and risk factors of EC in Nan'ao Island, where the EC incidence rate was chronically the highest in southern China. To calculate the annual incidence rate, data on 338 EC cases from Nan'ao Cancer Registry system diagnosed during 2005–2011 were collected. A case-control study was conducted to explore the EC risk fac...περισσότερα »
Cost-Effective Surgical Management of Liver Disease Amidst a Financial Crisis.
Cost-Effective Surgical Management of Liver Disease Amidst a Financial Crisis. World J Surg. 2016 Feb 25; Authors: Arkadopoulos N, Gemenetzis G, Danias N, Kokoropoulos P, Koukopoulou I, Bartsokas C, Kostopanagiotou G, Smyrniotis V Abstract BACKGROUND: Intraoperative use of specialized equipment and disposables contributes to the increasing cost of modern liver surgery. As a response to… Continue reading Cost-Effective Surgical Management of Liver Disease Amidst a Financial Crisis.
Pull-out retentive strength of fiber posts cemented at different times in canals obturated with a eugenol-based sealer
Publication date: Available online 26 February 2016 Source:The Journal of Prosthetic Dentistry Author(s): Khalil Aleisa, Ziad Nawaf AL-Dwairi, Sara A. Alsubait, Steven M. Morgano Statement of problemCurrently, no standard luting protocol exists for fiber posts. In addition, no agreement has been reached on the time interval between canal obturation and post space preparation and cementation.PurposeThe… Continue reading Pull-out retentive strength of fiber posts cemented at different times in canals obturated with a eugenol-based sealer
External Validation of Risk Stratification Models Predicting the Immediate Mortality After Open Repair of Ruptured AAA.
External Validation of Risk Stratification Models Predicting the Immediate Mortality After Open Repair of Ruptured AAA. World J Surg. 2016 Feb 25; Authors: Majd P, Mylonas S, Gawenda M, Brunkwall J Abstract BACKGROUND: Preoperative risk stratification of the immediate postoperative death after surgery may be helpful for the decision-making for patients with ruptured AAAs (rAAs).… Continue reading External Validation of Risk Stratification Models Predicting the Immediate Mortality After Open Repair of Ruptured AAA.
Stereotactic radiosurgery in combination with up-front high-dose methotrexate as a first-line treatment for newly diagnosed primary central nervous system lymphoma.
Related Articles Stereotactic radiosurgery in combination with up-front high-dose methotrexate as a first-line treatment for newly diagnosed primary central nervous system lymphoma. J Neurooncol. 2015 Jun;123(2):237-44 Authors: Hirono S, Iwadate Y, Higuchi Y, Serizawa T, Nagano O, Matsutani T, Saeki N Abstract The efficacy of stereotactic radiosurgery (SRS) instead of whole brain radiotherapy (WBRT) following… Continue reading Stereotactic radiosurgery in combination with up-front high-dose methotrexate as a first-line treatment for newly diagnosed primary central nervous system lym... περισσότερα »
Technique for identifying keratinized gingival tissue and soft tissue morphology on 3-dimensional implan t-planning software images
Publication date: Available online 26 February 2016 Source:The Journal of Prosthetic Dentistry Author(s): Toshio Kaku, Yoichiro Ogino, Yasuyuki Matsushita, Kiyoshi Koyano Preoperative 3-dimensional (3D) planning using cone beam computed tomography (CBCT) and 3D implant-planning software is used routinely for implant placement. However, despite its importance in planning surgical technique (conventional or flapless surgery) and prognosis,… Continue reading Technique for identifying keratinized gingival tissue and soft tissue morphology on 3-dimensional implan t-planning software images
Flexible endoscopic evaluation of swallowing (FEES) for neurogenic dysphagia: training curriculum of the German Society of Neurology and the German stroke society.
Flexible endoscopic evaluation of swallowing (FEES) for neurogenic dysphagia: training curriculum of the German Society of Neurology and the German stroke society. BMC Med Educ. 2016;16(1):70 Authors: Dziewas R, Glahn J, Helfer C, Ickenstein G, Keller J, Ledl C, Lindner-Pfleghar B, G Nabavi D, Prosiegel M, Riecker A, Lapa S, Stanschus S, Warnecke T, Busse… Continue reading Flexible endoscopic evaluation of swallowing (FEES) for neurogenic dysphagia: training curriculum of the German Society of Neurology and the German stroke society.
The Effect of Metformin on Hypothalamic-Pituitary-Thyroid Axis Activity in Women with Interferon-Induced Hypothyroidism: A Pilot Study
Exp Clin Endocrinol Diabetes 2016; 124: 71-76 DOI: 10.1055/s-0042-101163 Background: One of the most frequent adverse effects of interferon-α therapy is thyroiditis. Metformin was found to improve insulin sensitivity in hepatitis C patients, as well as to reduce elevated thyrotropin levels in patients with hypothyroidism. The aim of this study was to investigate the effect… Continue reading The Effect of Metformin on Hypothalamic-Pituitary-Thyroid Axis Activity in Women with Interferon-Induced Hypothyroidism: A Pilot Study
Contents
Publication date: March 2016 Source:The Journal of Emergency Medicine, Volume 50, Issue 3 from Emergencies via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1QjQGP6 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OA9ojw via IFTTT
Partial Contents of Volume 50, Number 4
Publication date: March 2016 Source:The Journal of Emergency Medicine, Volume 50, Issue 3 from Emergencies via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1QK6U9U via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OA9ojs via IFTTT
Emergency Department Presentations for Injuries in Older Adults Independently Known to be Victims of Elder Abuse
Publication date: March 2016 Source:The Journal of Emergency Medicine, Volume 50, Issue 3 Author(s): Tony Rosen, Elizabeth M. Bloemen, Veronica M. LoFaso, Sunday Clark, Neal E. Flomenbaum, Mark S. Lachs BackgroundElder abuse is under-recognized by emergency department (ED) providers, largely due to challenges distinguishing between abuse and accidental trauma.ObjectiveTo describe patterns and circumstances surrounding elder… Continue reading Emergency Department Presentations for Injuries in Older Adults Independently Known to be Victims of Elder Abuse
Mechanisms of Action of Liraglutide in Patients with Type 2 Diabetes Treated with High Dose Insulin.
Related Articles *Mechanisms of Action of Liraglutide in Patients with Type 2 Diabetes Treated with High Dose Insulin.* J Clin Endocrinol Metab. 2016 Feb 24;:jc20153906 Authors: Vanderheiden A, Harrison LB, Warshauer JT, Adams-Huet B, Li X, Yuan Q, Hulsey K, Dimitrov I, Yokoo T, Jaster AW, Pinho DF, Pedrosa I, Lenkinski RE, Pop LM, Lingvay I Abstract CONTEXT: The mechanisms of action of incretin mimetics in patients with long-standing type 2 diabetes (T2D) and high insulin requirements has not been studied. OBJECTIVE: To evaluate changes in beta-cell function, glucagon secretion,...περισσότερα »
Underdiagnoses and Undertreatment of Osteoporosis: The Battle to Be Won.
Related Articles *Underdiagnoses and Undertreatment of Osteoporosis: The Battle to Be Won.* J Clin Endocrinol Metab. 2016 Feb 24;:jc20153156 Authors: Miller PD Abstract CONTEXT: An expert opinion perspective on why osteoporosis is underdiagnosed and undertreated. OBJECTIVE: To highlight the potential reasons for why osteoporosis is undertreated. DESIGN: Literature review from PubMed, Plos One, and Science Direct search engines from 1900-2015 under terms: sub-trochanteric and atypical femur fractures, bisphosphonate clinical trial and bisphosphonate review articles, and treatment/...περισσότερα »
Aldosterone, Renin and Diabetes Mellitus in African Americans: The Jackson Heart Study.
Related Articles *Aldosterone, Renin and Diabetes Mellitus in African Americans: The Jackson Heart Study.* J Clin Endocrinol Metab. 2016 Feb 23;:jc20161002 Authors: Joseph JJ, Echouffo-Tcheugui JB, Kalyani RR, Yeh HC, Bertoni AG, Effoe VS, Casanova R, Sims M, Correa A, Wu WC, Wand GS, Golden SH Abstract CONTEXT: Previous research has suggested that activation of the renin-angiotensin-aldosterone system may promote insulin resistance and β-cell dysfunction but the association with incident diabetes in African Americans is unknown. OBJECTIVE: We examined the association between, bo... περισσότερα »
Lipids, Lipoproteins, and Cardiovascular Disease: Clinical Pharmacology Now and in the Future.
Related Articles *Lipids, Lipoproteins, and Cardiovascular Disease: Clinical Pharmacology Now and in the Future.* J Clin Endocrinol Metab. 2016 Feb 23;:jc20153940 Authors: Chait A, Eckel RH Abstract CONTEXT: While substantial benefit has accrued with respect to prevention and treatment of atherosclerotic cardiovascular disease (ASCVD) since the advent of statin therapy, much remains unknown and there is considerable need to address residual risk beyond statins. Moreover, many individuals are unable to tolerate statins. EVIDENCE ACQUISITION: As a result of several recent clinical ...περισσότερα »
A Perspective on the Evolving Landscape in Male Reproductive Medicine.
Related Articles *A Perspective on the Evolving Landscape in Male Reproductive Medicine.* J Clin Endocrinol Metab. 2016 Feb 23;:jc20153843 Authors: Bhasin S Abstract CONTEXT: Men's health and aging are emerging as important areas of research opportunity because of advances in reproductive biology and the recognition of men's health as a unique and important aspect of public health. EVIDENCE ACQUISITION: A perspective of the evolving landscape in male reproductive medicine. EVIDENCE SYNTHESIS: Remarkable discoveries in reproductive biology have greatly advanced the treatment of ere... περισσότερα »
Perspectives in Polycystic Ovary Syndrome: From Hair to Eternity.
Related Articles *Perspectives in Polycystic Ovary Syndrome: From Hair to Eternity.* J Clin Endocrinol Metab. 2016 Feb 23;:jc20153780 Authors: Dunaif A Abstract CONTEXT: Polycystic ovary syndrome (PCOS) is a common complex genetic disease. It is characterized by hyperandrogenism, gonadotropin secretory changes, polycystic ovarian morphology, and insulin resistance. The etiology of PCOS remains unknown, but modern genetic approaches, such as genome-wide association studies (GWAS), Mendelian randomization, and next-generation sequencing, promise to identify the pathways that are p... περισσότερα »
Pituitary Medicine From Discovery to Patient-Focused Outcomes.
Related Articles *Pituitary Medicine From Discovery to Patient-Focused Outcomes.* J Clin Endocrinol Metab. 2016 Feb 23;:jc20153653 Authors: Melmed S Abstract CONTEXT: This perspective traces a pipeline of discovery in pituitary medicine over the past 75 years. OBJECTIVE: To place in context past advances and predict future changes in understanding pituitary pathophysiology and clinical care. DESIGN: Author's perspective on reports of pituitary advances in the published literature. SETTING: Clinical and translational Endocrinology. OUTCOMES: Discovery of the hypothalamic-pituitary a...περισσότερα »
Precision Medicine Comes to Thyroidology.
Related Articles *Precision Medicine Comes to Thyroidology.* J Clin Endocrinol Metab. 2016 Feb 23;:jc20153695 Authors: Ladenson PW Abstract CONTEXT: The broad spectrum of thyroid disease severity-from subclinical hypothyroidism to myxedema coma, subclinical thyrotoxicosis to thyroid storm, and microscopic papillary to anaplastic cancers-has always demanded that clinicians individualize their management of thyroid patients. Deepening knowledge of thyroid pathophysiology along with advances in diagnostic, prognostic, and therapeutic technologies applicable to thyroid diseases posi... περισσότερα »
Relevance of radiobiological concepts in radionuclide therapy of cancer
10.3109/09553002.2016.1144944<br>Chandan Kumar from Anatomy Pathology via ola Kala on Inoreader http://ift.tt/1oMsMVX via IFTTT
Influence of nuclear structure on the formation of radiation-induced lethal lesions
10.3109/09553002.2016.1144941<br>Daniel A. Friedman from Anatomy Pathology via ola Kala on Inoreader http://ift.tt/1RstWiv via IFTTT
Radiotherapy-induced gut toxicity: Involvement of matrix metalloproteinases and the intestinal microvasculature
10.3109/09553002.2016.1146830<br>Romany L. Stansborough from Anatomy Pathology via ola Kala on Inoreader http://ift.tt/1oMsApB via IFTTT
Perspective on the Genetics and Diagnosis of Congenital Hyperinsulinism Disorders.
Related Articles *Perspective on the Genetics and Diagnosis of Congenital Hyperinsulinism Disorders.* J Clin Endocrinol Metab. 2016 Feb 23;:jc20153651 Authors: Stanley CA Abstract CONTEXT: Congenital hyperinsulinism (HI) is the most common cause of hypoglycemia in children. The risk of permanent brain injury in infants with HI continues to be as high as 25-50% due to delays in diagnosis and inadequate treatment. Congenital HI has been described since the birth of the JCEM under various terms, including "idiopathic hypoglycemia of infancy," "leucine-sensitive hypoglycemia," or "n... περισσότερα »
Genetics of Common Endocrine Disease: The Present and the Future.
Related Articles *Genetics of Common Endocrine Disease: The Present and the Future.* J Clin Endocrinol Metab. 2016 Feb 23;:jc20153640 Authors: Goodarzi MO Abstract CONTEXT: In honor of the 75th issue of the Journal of Clinical Endocrinology and Metabolism, the author was invited to present his perspectives on genetics in human endocrinology. This paper reviews what the field has achieved in the genetics of common endocrine disease, and offers predictions on where the field will move in the future and its impact on endocrine clinical practice. EVIDENCE ACQUISITION: The October 201...περισσότερα »
Bone and Mineral Metabolism: Where Are We, Where Are We Going, and How Will We Get There?
Related Articles *Bone and Mineral Metabolism: Where Are We, Where Are We Going, and How Will We Get There?* J Clin Endocrinol Metab. 2016 Feb 23;:jc20153607 Authors: Kronenberg HM Abstract CONTEXT: Advances in diagnosing and treating metabolic bone diseases will require ways to assess cellular signaling within human bones, ideally noninvasively. Only then will we be able to fully harness the increased molecular understanding of bone that derives from human genetics and model organisms, primarily rodents. New hormones regulating mineral ion homeostasis surely remain to be discov...περισσότερα »
Metabolite Signatures of Metabolic Risk Factors and their Longitudinal Changes.
Related Articles *Metabolite Signatures of Metabolic Risk Factors and their Longitudinal Changes.* J Clin Endocrinol Metab. 2016 Feb 23;:jc20152555 Authors: Yin X, Subramanian S, Willinger CM, Chen G, Juhasz P, Courchesne P, Chen BH, Li X, Hwang SJ, Fox CS, O'Donnell CJ, Muntendam P, Fuster V, Bobeldijk-Pastorova I, Sookoian SC, Pirola CJ, Gordon N, Adourian A, Larson MG, Levy D Abstract CONTEXT: Metabolic dysregulation underlies key metabolic risk factors-obesity, dyslipidemia, and dysglycemia. OBJECTIVE: To uncover mechanistic links between metabolomic dysregulation and metabo... περισσότερα »
Cost-Effective Surgical Management of Liver Disease Amidst a Financial Crisis.
*Cost-Effective Surgical Management of Liver Disease Amidst a Financial Crisis.* World J Surg. 2016 Feb 25; Authors: Arkadopoulos N, Gemenetzis G, Danias N, Kokoropoulos P, Koukopoulou I, Bartsokas C, Kostopanagiotou G, Smyrniotis V Abstract BACKGROUND: Intraoperative use of specialized equipment and disposables contributes to the increasing cost of modern liver surgery. As a response to the recent severe financial crisis in our country we have employed a highly standardized protocol of liver resection that minimizes intraoperative and postoperative costs. Our goal is to evaluate...περισσότερα »
External Validation of Risk Stratification Models Predicting the Immediate Mortality After Open Repair of Ruptured AAA.
*External Validation of Risk Stratification Models Predicting the Immediate Mortality After Open Repair of Ruptured AAA.* World J Surg. 2016 Feb 25; Authors: Majd P, Mylonas S, Gawenda M, Brunkwall J Abstract BACKGROUND: Preoperative risk stratification of the immediate postoperative death after surgery may be helpful for the decision-making for patients with ruptured AAAs (rAAs). The purpose of this study was to apply and validate the Glasgow aneurysm score (GAS) and the Hardman Index (HI) in predicting 30-day/in-hospital mortality in open surgical repair (OSR) and endovascular ... περισσότερα »
The Effect of Metformin on Hypothalamic-Pituitary-Thyroid Axis Activity in Women with Interferon-Induced Hypothyroidism: A Pilot Study
Exp Clin Endocrinol Diabetes 2016; 124: 71-76 DOI: 10.1055/s-0042-101163 Background: One of the most frequent adverse effects of interferon-α therapy is thyroiditis. Metformin was found to improve insulin sensitivity in hepatitis C patients, as well as to reduce elevated thyrotropin levels in patients with hypothyroidism. The aim of this study was to investigate the effect of metformin on hypothalamic-pituitary-thyroid axis activity in patients with interferon-induced thyroiditis. Methods: The study included 2 matched groups of women with type 2 diabetes and untreated subclinical ... περισσότερα »
The Incidence of Hypothyroidism Following the Radioactive Iodine Treatment of Graves' Disease and the Predictive Factors Influencing its Development.
*The Incidence of Hypothyroidism Following the Radioactive Iodine Treatment of Graves' Disease and the Predictive Factors Influencing its Development.* World J Nucl Med. 2016 Jan-Apr;15(1):30-7 Authors: Husseni MA Abstract The purpose of this study is to evaluate and compare the incidence of hypothyroidism following different fixed radioactive iodine-131 ((131)I) activities in the treatment of Graves' disease (GD) and to investigate the predictive factors that may influence its occurrence. This retrospective analysis was performed on 272 patients with GD who were treated with (13... περισσότερα »
Depth profile and mobility of (129)I and (137)Cs in soil originating from the Fukushima Dai-ichi Nuclear Power Plant accident.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Depth profile and mobility of (129)I and (137)Cs in soil originating from the Fukushima Dai-ichi Nuclear Power Plant accident.* J Environ Radioact. 2015 Aug;146:35-43 Authors: Honda M, Matsuzaki H, Miyake Y, Maejima Y, Yamagata T, Nagai H Abstract The (129)I derived from the FDNPP accident were clearly identified near the surface and showed a trend of rapid decrease with depth. The FDNPP (129)I and (137)Cs was 51.6 ± 1.7 mBq cm(-2) and 88.2 ± 27.1 kBq cm(-2) (average of four cores inventory) respectively. On avera... περισσότερα »
Impact of Nonvascular Thoracic MR Imaging on the Clinical Decision Making of Thoracic Surgeons: A 2-year Prospective Study.
Related Articles *Impact of Nonvascular Thoracic MR Imaging on the Clinical Decision Making of Thoracic Surgeons: A 2-year Prospective Study.* Radiology. 2016 Feb 24;:152004 Authors: Ackman JB, Gaissert HA, Lanuti M, Digumarthy SR, Shepard JO, Halpern EF, Wright CD Abstract Purpose To determine the impact of nonvascular thoracic magnetic resonance (MR) imaging on the clinical decision making and diagnostic certainty of thoracic surgeons. Materials and Methods Seven thoracic surgeons at Massachusetts General Hospital, an academic quaternary referral hospital, participated in this...περισσότερα »
Disrupted Resting-State Functional Connectivity in Nonmedicated Bipolar Disorder.
Related Articles *Disrupted Resting-State Functional Connectivity in Nonmedicated Bipolar Disorder.* Radiology. 2016 Feb 24;:151641 Authors: Wang Y, Zhong S, Jia Y, Sun Y, Wang B, Liu T, Pan J, Huang L Abstract Purpose To investigate the whole-brain intrinsic functional connectivity patterns of patients with bipolar disorder (BD). Materials and Methods This prospective study was approved by the research ethics committee, and all participants provided informed consent. Thirty-seven patients with nonmedicated BD II depression and 37 healthy control participants underwent resting-s... περισσότερα »
Pulmonary Artery Stiffness Is Independently Associated with Right Ventricular Mass and Function: A Cardiac MR Imaging Study.
Related Articles *Pulmonary Artery Stiffness Is Independently Associated with Right Ventricular Mass and Function: A Cardiac MR Imaging Study.* Radiology. 2016 Feb 24;:151527 Authors: Dawes TJ, Gandhi A, de Marvao A, Buzaco R, Tokarczuk P, Quinlan M, Durighel G, Diamond T, Monje-Garcia L, de Cesare A, Cook SA, O'Regan DP Abstract Purpose To determine the relationship between pulmonary artery (PA) stiffness and both right ventricular (RV) mass and function with cardiac magnetic resonance (MR) imaging. Materials and Methods The study was approved by the local research ethics commit... περισσότερα »
Practical PERCIST: A Simplified Guide to PET Response Criteria in Solid Tumors 1.0.
Related Articles *Practical PERCIST: A Simplified Guide to PET Response Criteria in Solid Tumors 1.0.* Radiology. 2016 Feb 24;:142043 Authors: O JH, Lodge MA, Wahl RL Abstract Positron Emission Tomography (PET) Response Criteria in Solid Tumors (PERCIST 1.0) describes in detail methods for controlling the quality of fluorine 18 fluorodeoxyglucose PET imaging conditions to ensure the comparability of PET images from different time points to allow quantitative expression of the changes in PET measurements and assessment of overall treatment response in PET studies. The steps for a...περισσότερα »
Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function.
*Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function.* PLoS One. 2016;11(2):e0149792 Authors: Fonseca MI, Chu S, Pierce AL, Brubaker WD, Hauhart RE, Mastroeni D, Clarke EV, Rogers J, Atkinson JP, Tenner AJ Abstract Chronic activation of the complement system and induced inflammation are associated with neuropathology in Alzheimer's disease (AD). Recent large genome wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) in the C3b/C4b receptor (CR1 or CD35) that are associated with late onset AD....περισσότερα »
Network-selective vulnerability of the human cerebellum to Alzheimer's disease and frontotemporal dementia.
*Network-selective vulnerability of the human cerebellum to Alzheimer's disease and frontotemporal dementia.* Brain. 2016 Feb 16; Authors: Guo CC, Tan R, Hodges JR, Hu X, Sami S, Hornberger M Abstract Neurodegenerative diseases are associated with distinct and distributed patterns of atrophy in the cerebral cortex. Emerging evidence suggests that these atrophy patterns resemble intrinsic connectivity networks in the healthy brain, supporting the network-based degeneration framework where neuropathology spreads across connectivity networks. An intriguing yet untested possibility i...περισσότερα »
A multi-layer network approach to MEG Connectivity Analysis.
Related Articles *A multi-layer network approach to MEG Connectivity Analysis.* Neuroimage. 2016 Feb 20; Authors: Brookes MJ, Tewarie PK, Hunt BA, Robson SE, Gascoyne LE, Liddle EB, Liddle PF, Morris PG Abstract Recent years have shown the critical importance of inter-regional neural network connectivity in supporting healthy brain function. Such connectivity is measurable using neuroimaging techniques such as MEG, however the richness of the electrophysiological signal makes gaining a complete picture challenging. Specifically, connectivity can be calculated as statistical inte...περισσότερα »
The Effect of Short-Term Auditory Training on Speech in Noise Perception and Cortical Auditory Evoked Potentials in Adults with Cochlear Implants
Semin Hear 2016; 37: 099-100 DOI: 10.1055/s-0036-1579698 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA. Article in Thieme eJournals: Table of contents | Full text from #Audiology via ola Kala on Inoreader http://ift.tt/1Q7AySN via IFTTT
Relevance of radiobiological concepts in radionuclide therapy of cancer
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 36 δευτερόλεπτα
10.3109/09553002.2016.1144944<br>Chandan Kumar from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1oMsMVX via IFTTT
Influence of nuclear structure on the formation of radiation-induced lethal lesions
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 36 δευτερόλεπτα
10.3109/09553002.2016.1144941<br>Daniel A. Friedman from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1RstWiv via IFTTT
An appraisal of current dysphagia diagnosis and treatment strategies.
Related Articles An appraisal of current dysphagia diagnosis and treatment strategies. Expert Rev Gastroenterol Hepatol. 2016 Feb 24; Authors: Kaindlstorfer A, Pointner R Abstract Dysphagia is a common, serious health problem with a wide variety of etiologies and manifestations. This review gives a general overview of diagnostic and therapeutic options for oropharyngeal as well as… Continue reading An appraisal of current dysphagia diagnosis and treatment strategies.
Utility of Esophagram versus High-Resolution Manometry in the Detection of Esophageal Dysmotility.
Related Articles Utility of Esophagram versus High-Resolution Manometry in the Detection of Esophageal Dysmotility. Otolaryngol Head Neck Surg. 2016 Feb 23; Authors: O’Rourke AK, Lazar A, Murphy B, Castell DO, Martin-Harris B Abstract OBJECTIVE: This study compared barium esophagram with high-resolution esophageal manometry (HRM) results to determine whether esophagram is an adequate screening examination for… Continue reading Utility of Esophagram versus High-Resolution Manometry in the Detection of Esophageal Dysmotility.
Clinical and Prognostic Factors Associated With Survival in Mexican Patients With Idiopathic Inflammatory Myopathies.
Related Articles Clinical and Prognostic Factors Associated With Survival in Mexican Patients With Idiopathic Inflammatory Myopathies. J Clin Rheumatol. 2016 Mar;22(2):51-6 Authors: Galindo-Feria AS, Rojas-Serrano J, Hinojosa-Azaola A Abstract BACKGROUND: Factors associated with survival in patients with idiopathic inflammatory myopathies are heterogeneous. OBJECTIVE: This study aimed to describe clinical and prognostic factors associated with survival… Continue reading Clinical and Prognostic Factors Associated With Survival in Mexican Patients With Idiopathic Inflammatory Myopathies.
IJMS, Vol. 17, Pages 298: Immunohistochemical Analysis of Cerebral Thrombi Retrieved by Mechanical Thrombectomy from Patients with Acute Ischemic Stroke
Mechanical thrombectomy is a novel treatment option for patients with acute ischemic stroke (AIS). Only a few studies have previously suggested strategies to categorize retrieved clots according to their histologic composition. However, these reports did not analyze potential biomarkers that are of importance in stroke-related inflammation. We therefore histopathologically investigated 37 intracerebral thrombi mechanically retrieved… Continue reading IJMS, Vol. 17, Pages 298: Immunohistochemical Analysis of Cerebral Thrombi Retrieved by Mechanical Thrombectomy from Patients with Acu... περισσότερα »
Surgical Management of Barrett’s Esophagus.
Related Articles Surgical Management of Barrett’s Esophagus. Gastroenterol Clin North Am. 2015 Jun;44(2):459-71 Authors: Peyre CG, Watson TJ Abstract Patients with gastroesophageal reflux disease and Barrett’s esophagus can be a management challenge for the treating physician or surgeon. The goals of therapy include relief of reflux symptoms, induction of histologic regression, and prevention of progression… Continue reading Surgical Management of Barrett’s Esophagus.
GLOSSALGIA SYNDROME AS SUPRAESOPHAGEAL MANIFESTATION OF GASTROESOPHAGEAL REFLUX DISEASE.
Related Articles [GLOSSALGIA SYNDROME AS SUPRAESOPHAGEAL MANIFESTATION OF GASTROESOPHAGEAL REFLUX DISEASE]. Eksp Klin Gastroenterol. 2015;(6):95-8 Authors: Ostrovskaya LY, Bulkina NV, Osipova UL Abstract The case of clinical supervision of the patient having polimorbid pathology is presented. One of extraesophageal manifestations of a gastroesophageal reflux disease is the glossalgia. Glossalgia is the polyetiological disease. Treatment needs… Continue reading GLOSSALGIA SYNDROME AS SUPRAESOPHAGEAL MANIFESTATION OF GASTROESOPHAGEAL REFLUX DISEASE.
IJMS, Vol. 17, Pages 294: The Human Host Defense Ribonucleases 1, 3 and 7 Are Elevated in Patients with Sepsis after Major Surgery—A Pilot Study
Sepsis is the most common cause of death in intensive care units and associated with widespread activation of host innate immunity responses. Ribonucleases (RNases) are important components of the innate immune system, however the role of RNases in sepsis has not been investigated. We evaluated serum levels of RNase 1, 3 and 7 in 20… Continue reading IJMS, Vol. 17, Pages 294: The Human Host Defense Ribonucleases 1, 3 and 7 Are Elevated in Patients with Sepsis after Major Surgery—A Pilot Study
A mixed treatment comparison to compare the efficacy and safety of botulinum toxin treatments for cervical dystonia.
A mixed treatment comparison to compare the efficacy and safety of botulinum toxin treatments for cervical dystonia. J Neurol. 2016 Feb 25; Authors: Han Y, Stevens AL, Dashtipour K, Hauser RA, Mari Z Abstract A systematic pair-wise comparison of all available botulinum toxin serotype A and B treatments for cervical dystonia (CD) was conducted, as… Continue reading A mixed treatment comparison to compare the efficacy and safety of botulinum toxin treatments for cervical dystonia.
IJMS, Vol. 17, Pages 301: Reduced Connexin26 in the Mature Cochlea Increases Susceptibility to Noise-Induced Hearing Lossin Mice
Connexin26 (Cx26, encoded by GJB2) mutations are the most common cause of non-syndromic deafness. GJB2 is thought to be involved in noise-induced hearing loss (NIHL). However, the role of Cx26 in NIHL is still obscure. To explore the association between Cx26 and NIHL, we established a Cx26 knockdown (KD) mouse model by conditional knockdown of… Continue reading IJMS, Vol. 17, Pages 301: Reduced Connexin26 in the Mature Cochlea Increases Susceptibility to Noise-Induced Hearing Lossin Mice
Safety of Ultrasound-Guided Botulinum Toxin Injections for Sialorrhea as Performed by Pediatric Otolaryngologists.
Related Articles Safety of Ultrasound-Guided Botulinum Toxin Injections for Sialorrhea as Performed by Pediatric Otolaryngologists. Otolaryngol Head Neck Surg. 2016 Feb 23; Authors: Shariat-Madar B, Chun RH, Sulman CG, Conley SF Abstract OBJECTIVE: To evaluate incidence of complications and hospital readmission as a result of ultrasound-guided botulinum toxin injections to manage sialorrhea. STUDY DESIGN: Case… Continue reading Safety of Ultrasound-Guided Botulinum Toxin Injections for Sialorrhea as Performed by Pediatric Otolaryngologists.
Development of a Statistical Model for the Prediction of Common Vestibular Diagnoses.
*Development of a Statistical Model for the Prediction of Common Vestibular Diagnoses.* JAMA Otolaryngol Head Neck Surg. 2016 Feb 25; Authors: Friedland DR, Tarima S, Erbe C, Miles A Abstract Importance: Treatment of patients with vestibular disorders can be complex, requires lengthy clinic visit time, and uses greater clinical resources for diagnosis. A pre-encounter intake questionnaire may predict the most common disorders, allowing for more efficient allocation of resources and use of clinicians. Objective: To develop a statistical model for predicting vestibular diagnoses, p...περισσότερα »
Rhabdomyolysis after lamotrigine overdose: a case report and review of the literature.
*Rhabdomyolysis after lamotrigine overdose: a case report and review of the literature.* Ann Gen Psychiatry. 2016;15:6 Authors: Karaoulanis SE, Syngelakis M, Fokas K Abstract BACKGROUND: Lamotrigine is an effective anticonvulsant drug that has also been demonstrated to be effective in the treatment of bipolar disorder. We report a case of rhabdomyolysis after intentional overdose in a woman aged 48. CASE PRESENTATION: A 48-year-old female presented to the emergency department after an acute ingestion of 6 g of lamotrigine. The patient suffered from bipolar disorder, and she was t...περισσότερα »
[Intratympanic versus systemic steroid initial treatment for idiopathic sudden hearing loss: a Meta-analysis].
*[Intratympanic versus systemic steroid initial treatment for idiopathic sudden hearing loss: a Meta-analysis].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(22):1970-7 Authors: Chen P, Wang S, Zhang Y, Huang H, Zhang C, Xiao Z Abstract OBJECTIVE: To assess the efficacy and safety of glucocorticoid in initial treatment of sudden hearing loss with intratympanic (IT) and systemic ways. METHOD: We searched the database of PubMed, Cochrane, Embase,CBM, CNKI, VIP, Wanfang systematically. Literatures were screened according to the preestablished inclusion and exclusion sta...περισσότερα »
[Clinical analysis of idiopathic sudden sensorineural hearing loss with vertigo].
*[Clinical analysis of idiopathic sudden sensorineural hearing loss with vertigo].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(22):1963-5, 1969 Authors: Gong N, Zhang X, Ge L, Xu D Abstract OBJECTIVE: To explore the clinical characteristics and prognosis of patients with idiopathic sudden sensorineural hearing loss (ISSHL) with vertigo. METHOD: By analyzing the clinical data of 271 ISSHL patients, they were divided into without vertigo group (n = 169) and vertigo group (n = 102). In vertigo group, 34 cases were patients with benign paroxysmal positional vertigo (... περισσότερα »
[Prognostic factors of sudden sensorineural hearing loss in children].
*[Prognostic factors of sudden sensorineural hearing loss in children].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(22):1931-5 Authors: Li F, Xue X, Wang L, Yang F, Wang H, Guan J, Du W, Xiong W, Wu K, Wu M, Yin Z, Lan L, Wang D, Wang Q Abstract OBJECTIVE: The aim of this retrospective study was to analyze the recovery rate of sudden sensorineural hearing loss in children, and explore the prognostic factors in order to guide the clinical diagnosis and treatment. METHOD: A retrospective review was conducted for the prognosis of children with sudden sensorineural hea...περισσότερα »
[St. John's Wort for aura and vertigo].
Related Articles *[St. John's Wort for aura and vertigo].* MMW Fortschr Med. 2015 Sep 24;157(16):24 Authors: Fueßl HS, Stiefelhagen P PMID: 26783610 [PubMed - indexed for MEDLINE] from Hearing and Balance via ola Kala on Inoreader http://ift.tt/1QhOCdX via IFTTT
EEG based evaluation of stereoscopic 3D displays for viewer discomfort.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *EEG based evaluation of stereoscopic 3D displays for viewer discomfort.* Biomed Eng Online. 2015;14:21 Authors: Malik AS, Khairuddin RN, Amin HU, Smith ML, Kamel N, Abdullah JM, Fawzy SM, Shim S Abstract BACKGROUND: Consumer preference is rapidly changing from 2D to 3D movies due to the sensational effects of 3D scenes, like those in Avatar and The Hobbit. Two 3D viewing technologies are available: active shutter glasses and passive polarized glasses. However, there are consistent reports... περισσότερα »
N-acetyl-L-leucine accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *N-acetyl-L-leucine accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus.* PLoS One. 2015;10(3):e0120891 Authors: Günther L, Beck R, Xiong G, Potschka H, Jahn K, Bartenstein P, Brandt T, Dutia M, Dieterich M, Strupp M, la Fougère C, Zwergal A Abstract An acute unilateral vestibular lesion leads to a vestibular tone imbalance with nystagmus, head roll tilt and postural imbalance. These deficits gradually decrease over days to weeks du... περισσότερα »
Unemployment in the United States after traumatic brain injury for working-age individuals: prevalence and associated factors 2 years postinjury.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Unemployment in the United States after traumatic brain injury for working-age individuals: prevalence and associated factors 2 years postinjury.* J Head Trauma Rehabil. 2015 May-Jun;30(3):160-74 Authors: Cuthbert JP, Harrison-Felix C, Corrigan JD, Bell JM, Haarbauer-Krupa JK, Miller AC Abstract OBJECTIVE: To estimate the prevalence of unemployment and part-time employment in the United States for working-age individuals completing rehabilitation for a primary diagnosis of traumatic brain injury (TBI) between 20... περισσότερα »
The impact of social support at home on health-related quality of life among veterans with spinal cord injury participating in a supported employment program.
[image: http:--production.springer.de-OnlineReso] Related Articles *The impact of social support at home on health-related quality of life among veterans with spinal cord injury participating in a supported employment program.* Qual Life Res. 2015 Jul;24(7):1741-7 Authors: Sutton BS, Ottomanelli L, Njoh E, Barnett SD, Goetz LL Abstract PURPOSE: To investigate the impact of social support at home on health-related quality of life (HRQOL) as measured by the VR-6D utility index for spinal cord injury (SCI) veterans participating in a program of supported employment (SE). METHODS: We... περισσότερα »
Lymphoma of the Internal Auditory Canal Presenting as Facial Palsy, Vertigo, and Hearing Loss.
*Lymphoma of the Internal Auditory Canal Presenting as Facial Palsy, Vertigo, and Hearing Loss.* J Int Adv Otol. 2015 Dec;11(3):262-263 Authors: Ryou N, Ko DY, Jun HJ, Chae SW Abstract The combined symptoms of vertigo, hearing loss, and facial palsy indicate the presence of lesions in the internal auditory canal (IAC). Differential diagnoses, such as inner/middle ear infections and IAC neoplasms, can make the definitive diagnosis of IAC lymphomas challenging. Lymphomas can infiltrate the central nervous system at various sites; however, IAC involvement in metastatic lymphomas is ... περισσότερα »
[Pleuropulmonary blastoma: case report].
*[Pleuropulmonary blastoma: case report].* Arch Argent Pediatr. 2016 Feb;114(1):e25-e28 Authors: Bosch JJ, Medín M, Garrido P, Martínez J, Teper A Abstract Pleuropulmonary blastoma is a rare lung tumor of childhood that can occur with cystic or solid lesions, as a radiological finding with or without respiratory symptoms. We report the case of a 2 year old toddler in his first pulmonary obstructive episode with suspected toracic malformation of the left upper lobe in his chest x-ray and tomography. Surgery was performed showing cystic malformation of the left upper lobe. We receiv... περισσότερα »
A very rare case of a small bowel leiomyosarcoma leading to ileocaecal intussusception treated with a laparoscopic resection: a case report and a literature review.
*A very rare case of a small bowel leiomyosarcoma leading to ileocaecal intussusception treated with a laparoscopic resection: a case report and a literature review.* World J Surg Oncol. 2016;14(1):48 Authors: Guzel T, Mech K, Mazurkiewicz M, Dąbrowski B, Lech G, Chaber A, Słodkowski M Abstract BACKGROUND: Small bowel tumours are rare and comprise less than 2 % of all primary gastrointestinal neoplasms. Among these tumours, a leiomyosarcoma belonging to soft tissue sarcomas is extremely rare and accounts for about 1 % of malignant mesenchymal lesions in the gastrointestinal tract... περισσότερα »
Small bowel neuroendocrine tumors: From pathophysiology to clinical approach.
Related Articles *Small bowel neuroendocrine tumors: From pathophysiology to clinical approach.* World J Gastrointest Pathophysiol. 2016 Feb 15;7(1):117-24 Authors: Xavier S, Rosa B, Cotter J Abstract Neuroendocrine tumors (NETs), defined as epithelial tumors with predominant neuroendocrine differentiation, are among the most frequent types of small bowel neoplasm. They represent a rare, slow-growing neoplasm with some characteristics common to all forms and others attributable to the organ of origin. The diagnosis of this subgroup of neoplasia is not usually straight-forward fo...περισσότερα »
Rectal neuroendocrine tumor with uncommon metastatic spread: A case report and review of literature.
Related Articles *Rectal neuroendocrine tumor with uncommon metastatic spread: A case report and review of literature.* World J Gastrointest Oncol. 2016 Feb 15;8(2):231-4 Authors: Tsoukalas N, Galanopoulos M, Tolia M, Kiakou M, Nakos G, Papakostidi A, Koumakis G Abstract Neuroendocrine tumors of the gastrointestinal tract are rare neoplasms. Rectal neuroendocrine tumors consist approximately the 5%-14% of all neuroendocrine neoplasms in Europe. These tumors are diagnosed in relatively young patients, with a mean age at diagnosis of 56 years. Distant metastases from rectal neuroe...περισσότερα »
Metastatic Melanoma of the Bilateral Parotid Glands.
Related Articles *Metastatic Melanoma of the Bilateral Parotid Glands.* West Indian Med J. 2016 Jan 12;65(1) Authors: Cengız BP, Acar M, Aksay C, Cantürk YK Abstract Melanoma is the most serious form of skin cancers and life-time risk of melanoma is increasing rapidly both in men and women. Melanoma in the parotid gland is seen rarely and it is more likely to be metastatic disease. We present here a rare case of metastatic malignant melanoma from the forehead skin to the parotid glands bilaterally. PMID: 26907988 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala o...περισσότερα »
Whole exome sequencing of rare aggressive breast cancer histologies.
Related Articles *Whole exome sequencing of rare aggressive breast cancer histologies.* Breast Cancer Res Treat. 2016 Feb 23; Authors: Dieci MV, Smutná V, Scott V, Yin G, Xu R, Vielh P, Mathieu MC, Vicier C, Laporte M, Drusch F, Guarneri V, Conte P, Delaloge S, Lacroix L, Fromigué O, André F, Lefebvre C Abstract Little is known about mutational landscape of rare breast cancer (BC) subtypes. The aim of the study was to apply next generation sequencing to three different subtypes of rare BCs in order to identify new genes related to cancer progression. We performed whole exome and ... περισσότερα »
Phosphatase and Tensin Homolog Is a Potential Target for Ovarian Cancer Sensitization to Cytotoxic Agents.
Related Articles *Phosphatase and Tensin Homolog Is a Potential Target for Ovarian Cancer Sensitization to Cytotoxic Agents.* Int J Gynecol Cancer. 2016 Feb 22; Authors: McCormick A, Earp E, Leeson C, Dixon M, O'Donnell R, Kaufmann A, Edmondson RJ Abstract OBJECTIVES: The phosphatase and tensin homolog (PTEN) tumor suppressor protein has been found to be inactivated or mutated in various human malignancies and to play a role in cisplatin and poly(ADP-ribose) polymerase inhibitor sensitivity. In this study, we assessed the association of PTEN loss with homologous recombination (H... περισσότερα »
Genome wide DNA methylation profiles provide clues to the origin and pathogenesis of germ cell tumors.
Related Articles *Genome wide DNA methylation profiles provide clues to the origin and pathogenesis of germ cell tumors.* PLoS One. 2015;10(4):e0122146 Authors: Rijlaarsdam MA, Tax DM, Gillis AJ, Dorssers LC, Koestler DC, de Ridder J, Looijenga LH Abstract The cell of origin of the five subtypes (I-V) of germ cell tumors (GCTs) are assumed to be germ cells from different maturation stages. This is (potentially) reflected in their methylation status as fetal maturing primordial germ cells are globally demethylated during migration from the yolk sac to the gonad. Imprinted regions... περισσότερα »
[RARE CASE OF STOMACH CANCER METASTASIS].
Related Articles *[RARE CASE OF STOMACH CANCER METASTASIS].* Urologiia. 2015 Sep-Oct;(5):81 Authors: Yerko IP, Moloshok AA, Tsiselsky RK Abstract The article presents the description of the case of metastasis of stomach cancer in the right testicle and epididymis, cellular tissue along the spermatic cord, prepuce and scrotum in the absence of metastases in the peritoneum and abdominal organs. PMID: 26859945 [PubMed - indexed for MEDLINE] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1oMoKwI via IFTTT
Isolated Ocular Relapse in Childhood Acute Lymphoblastic Leukemia during Second Interim Maintenance Phase of Chemotherapy: Case Report.
Related Articles *Isolated Ocular Relapse in Childhood Acute Lymphoblastic Leukemia during Second Interim Maintenance Phase of Chemotherapy: Case Report.* J Med Assoc Thai. 2015 Nov;98(11):1150-3 Authors: Monsereenusorn C, Rujkijyanont P, Srimanan W, Traivaree C Abstract More than 80% of acute lymphoblastic leukemia (ALL) in pediatric population is curable by using combinations of chemotherapy. However, 20% of the cases still suffer from disease relapse. The most common site of relapse is bone marrow. Relapse of childhood ALL involving the eyeball is rare. However, it occurs in 2... περισσότερα »
Diagnosis of Xp11.2 Translocation Renal Cell Carcinomas in the Thai Patients.
Related Articles *Diagnosis of Xp11.2 Translocation Renal Cell Carcinomas in the Thai Patients.* J Med Assoc Thai. 2015 Nov;98(11):1133-8 Authors: Junthaworn B, Pradniwat K, Hanamornroongruang S Abstract BACKGROUND: Xp11.2 translocation renal cell carcinomas (TRCCs) are rare tumors recently accepted as a separated tumor type in 2004 WHO classification. To diagnose these tumors, histological recognition and confirmation of translocation are necessary. While the incidence of overall renal cell carcinomas (RCCs) is increased after the age of 40, Xp11.2 TRCCs are predominantly repor...περισσότερα »
Extreme Spindles and Leukoencephalopathy after Acute Lymphoblastic Leukemia Treatment: An Undescribed Association.
Related Articles *Extreme Spindles and Leukoencephalopathy after Acute Lymphoblastic Leukemia Treatment: An Undescribed Association.* Neurodiagn J. 2015 Dec;55(4):235-42 Authors: Kanda PA, Kanda RG, Mei PA, Cury IJ Abstract We report a case of a child whose EEG demonstrated extreme spindles (ES) after acute lymphoblastic leukemia treatment. This finding has not been reported previously. In 1962, Gibbs and Gibbs described the ES EEG pattern due to its high amplitude (200 to 400 μV). ES are a rare spindle variant that is found in EEGs of 0.05% of normal children (average age, 3 yea... περισσότερα »
Concurrent chemoradiotherapy with elective lymph node irradiation for esophageal cancer: a systemic review and pooled analysis of the literature
Concurrent chemoradiotherapy with elective lymph node irradiation for esophageal cancer: a systemic review and pooled analysis of the literature: Summary Concurrent chemoradiotherapy (CCRT) has been accepted as the standard non-surgical treatment for esophageal cancer. However, no consistent conclusions have been reached whether elective lymph node irradiation (ENI) should be delivered. Therefore, we performed a systematic review and pooled analysis to evaluate the value of CCRT with ENI. A literature search based on PubMed, Embase and Google Scholar was carried out and all of the s...περισσότερα »
Thymus-expressed chemokine enhances Porphyromonas gingivalis LPS-induced osteoclast formation
Thymus-expressed chemokine enhances Porphyromonas gingivalis LPS-induced osteoclast formation via NFATc1 activation via Oral Biology Publication date: June 2016 *Source:*Archives of Oral Biology, Volume 66 Author(s): Michihiko Usui, Yoshimasa Okamatsu, Tsuyoshi Sato, Tomoya Hanatani, Yuki Moritani, Kotaro Sano, Matsuo Yamamoto, Keisuke Nakashima ObjectiveP. gingivalis is a gram-negative anaerobic bacterium and a major periodontal pathogen. LPS produced by P. gingivalis promotes osteoclast formation. TECK is a CC chemokine whose expression is increased in gingival epithelial cells expos... περισσότερα »
Measuring Nontechnical Aspects of Surgical Clinician Development in an Otolaryngology Residency Training Program.
Measuring Nontechnical Aspects of Surgical Clinician Development in an Otolaryngology Residency Training Program.: JAMA Otolaryngol Head Neck Surg. 2016 Feb 25; Authors: Shin JJ, Cunningham MJ, Emerick KG, Gray ST Abstract Importance: Surgical competency requires sound clinical judgment, a systematic diagnostic approach, and integration of a wide variety of nontechnical skills. This more complex aspect of clinician development has traditionally been difficult to measure through standard assessment methods. Objective: This study was conducted to use the Clinical Practice Instrument ... περισσότερα »
Static balance function in children with a history of preterm birth.
*Static balance function in children with a history of preterm birth.* Med J Islam Repub Iran. 2015;29:310 Authors: Eshaghi Z, Jafari Z, Jalaie S Abstract BACKGROUND: The incomplete maturation of brain in preterm children results in long-term neurodevelopmental impairment. This study aimed to investigate the static balance function in children with a history of preterm birth. METHODS: Participants were 31 preterm children including 21 moderately preterm (MPT), 10 very preterm (VPT), and 20 term children aged 5.5 and 6.5 years. The cervical vestibular-evoked myogenic potential (cVEM...περισσότερα »
Pelvic angioembolization in trauma - Indications and outcomes.
*Pelvic angioembolization in trauma - Indications and outcomes.* Int J Surg. 2016 Feb 18; Authors: Salcedo ES, Brown IE, Corwin MT, Galante JM Abstract INTRODUCTION: Pelvic stabilization with angioembolization (AE) is steadily supplanting operative management for the treatment of pelvic hemorrhage in trauma. We aimed to provide a brief review of the indications, effectiveness and complications associated with AE for pelvic injuries. METHODS: We conducted a literature search using the terms "trauma," "angioembolization," and "pelvis" limited to studies published in the English lang...περισσότερα »
Risk factors affecting morbidity and mortality following emergency laparotomy for small bowel obstruction: A retrospective cohort study.
*Risk factors affecting morbidity and mortality following emergency laparotomy for small bowel obstruction: A retrospective cohort study.* Int J Surg. 2016 Feb 18; Authors: Jeppesen MH, Tolstrup MB, Watt SK, Gögenur I Abstract INTRODUCTIONS: To identify risk factors for increased 30-day morbidity and mortality, using standardized measuring tools for the characterization of complications after emergency surgery for small bowel obstruction. METHODS: A retrospective cohort study including patients treated with emergency laparotomy for small bowel obstruction at a Copenhagen University...περισσότερα »
Active Staphylococcus aureus infection: Is it a contra-indication to the repair of complex hernias with synthetic mesh? A prospective observational study on the outcomes of synthetic mesh replacement, in patients with chronic mesh infection caused by Staphylococcus aureus.
*Active Staphylococcus aureus infection: Is it a contra-indication to the repair of complex hernias with synthetic mesh? A prospective observational study on the outcomes of synthetic mesh replacement, in patients with chronic mesh infection caused by Staphylococcus aureus.* Int J Surg. 2016 Feb 18; Authors: Birolini C, Santos de Miranda J, Utiyama EM, Rasslan S, Birolini D Abstract INTRODUCTION: The management of chronic mesh infection is challenging and controversial. The use of synthetic material to repair the abdominal wall in the infected setting is not recommended, especiall...περισσότερα »
Irrigation versus suction alone during laparoscopic appendectomy; a randomized controlled equivalence trial.
*Irrigation versus suction alone during laparoscopic appendectomy; a randomized controlled equivalence trial.* Int J Surg. 2016 Feb 18; Authors: Snow HA, Choi JM, Cheng MW, Chan ST Abstract INTRODUCTION: The objective of this study was to compare operative peritoneal irrigation versus suction alone during laparoscopic appendectomy in adult patients; our hypothesis was that the two methods are equivalent in terms of rate of post-operative intra-abdominal abscess. There has been only one prospective, randomized, superiority trial in children, that showed non-significant difference ... περισσότερα »
Pancreaticoduodenectomy for Adenocarcinoma of the Pancreatic Head is Justified in Elderly Patients.
Related Articles *Pancreaticoduodenectomy for Adenocarcinoma of the Pancreatic Head is Justified in Elderly Patients.* Int J Surg. 2016 Feb 20; Authors: Renz BW, Khalil PN, Mikhailov M, Graf S, Schiergens TS, Niess H, Boeck S, Heinemann V, Hartwig W, Werner J, Bruns CJ, Kleespies A Abstract BACKGROUND: The increasing elderly population is an inevitable trend worldwide in developed countries. Therefore, we aimed to assess the experience of a tertiary pancreatic center with a very homogenous population comprising only patients diagnosed with PDAC of the pancreatic head in patients...περισσότερα »
Predictors of Circumferential Resection Margin Involvement in Surgically Resected Rectal Cancer: A Retrospective Review of the US National Cancer Database.
Related Articles *Predictors of Circumferential Resection Margin Involvement in Surgically Resected Rectal Cancer: A Retrospective Review of the US National Cancer Database.* Int J Surg. 2016 Feb 20; Authors: Al-Sukhni E, Attwood K, Gabriel E, Nurkin SJ Abstract INTRODUCTION: The circumferential resection margin (pre-operative CRM) is a key prognostic factor after rectal cancer resection. We sought to identify factors associated with CRM involvement (CRM+). METHODS: A retrospective review was performed of the National Cancer Database, 2004-2011. Patients with rectal cancer who un... περισσότερα »
Re: A simplified approach to reconstruction of hemipelvectomy defects with lower extremity free fillet flaps to minimize ischaemia time.
Related Articles *Re: A simplified approach to reconstruction of hemipelvectomy defects with lower extremity free fillet flaps to minimize ischaemia time.* J Plast Reconstr Aesthet Surg. 2016 Feb 10; Authors: Strong B, Ragbir M PMID: 26906555 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1Q7uHNo via IFTTT
3D printing provides unrivalled bespoke teaching tools for autologous free flap breast reconstruction.
Related Articles *3D printing provides unrivalled bespoke teaching tools for autologous free flap breast reconstruction.* J Plast Reconstr Aesthet Surg. 2016 Jan 18; Authors: Mehta S, Byrne N, Karunanithy N, Farhadi J PMID: 26906554 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1Q7uERL via IFTTT
Comparison of survival, safety, and efficacy after transarterial chemoembolization and radioembolization of Barcelona Clinic Liver Cancer stage B-C hepatocellular cancer patients.
Related Articles *Comparison of survival, safety, and efficacy after transarterial chemoembolization and radioembolization of Barcelona Clinic Liver Cancer stage B-C hepatocellular cancer patients.* Nucl Med Commun. 2016 Feb 22; Authors: Soydal C, Arslan MF, Kucuk ON, Idilman R, Bilgic S Abstract AIM: This study aimed to compare the overall survival (OS) times, long-term complications, and recurrence rates of chemoembolization and radioembolization for Barcelona Clinic Liver Cancer (BCLC) stage B-C hepatocellular cancer patients. MATERIALS AND METHODS: This retrospective study in... περισσότερα »
News and Views - April 2016.
Related Articles *News and Views - April 2016.* Nucl Med Commun. 2016 Apr;37(4):435-6 Authors: PMID: 26905023 [PubMed - in process] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1Uo3Way via IFTTT
Lateral Skull Base Attenuation in Patients with Anterior Cranial Fossa Spontaneous Cerebrospinal Fluid Leaks.
Related Articles *Lateral Skull Base Attenuation in Patients with Anterior Cranial Fossa Spontaneous Cerebrospinal Fluid Leaks.* Otolaryngol Head Neck Surg. 2016 Feb 23; Authors: O'Connell BP, Stevens SM, Xiao CC, Meyer TA, Schlosser RJ Abstract OBJECTIVE: (1) Determine if patients with anterior fossa spontaneous cerebrospinal fluid (SCSF) leaks demonstrate lateral skull base bone attenuation. (2) Examine the relation between body mass index (BMI; kg/m(2)) and skull base thickness. STUDY DESIGN: Retrospective cohort study. SETTING: Tertiary care hospital. SUBJECTS AND METHODS: Ret... περισσότερα »
It is rocket science - why dietary nitrate is hard to Beet! part II: further mechanisms and therapeutic potential of the nitrate-nitrite-NO pathway.
*It is rocket science - why dietary nitrate is hard to Beet! part II: further mechanisms and therapeutic potential of the nitrate-nitrite-NO pathway.* Br J Clin Pharmacol. 2016 Feb 23; Authors: Mills CE, Khatri J, Maskell P, Odongerel C, Webb AJ Abstract Dietary nitrate (found in green leafy vegetables such as rocket and in beetroot) is now recognised to be an important source of nitric oxide, via the nitrate-nitrite-NO pathway. Dietary nitrate confers several cardiovascular beneficial effects on blood pressure, platelets, endothelial function, mitochondrial efficiency and exerci... περισσότερα »
Treatment results and prognostic factors for advanced squamous cell carcinoma of the head and neck treated with salvage surgery after concurrent chemoradiotherapy.
Related Articles *Treatment results and prognostic factors for advanced squamous cell carcinoma of the head and neck treated with salvage surgery after concurrent chemoradiotherapy.* Int J Clin Oncol. 2016 Feb 23; Authors: Taguchi T, Nishimura G, Takahashi M, Shiono O, Komatsu M, Sano D, Yabuki KI, Arai Y, Yamashita Y, Yamamoto K, Sakuma Y, Oridate N Abstract BACKGROUND: For primary organ preservation, concurrent chemoradiotherapy (CCRT) is performed for advanced squamous cell carcinoma of the head and neck (SCCHN). In this organ-preservation setting with CCRT, surgery is reserv... περισσότερα »
Development of a Statistical Model for the Prediction of Common Vestibular Diagnoses.
Development of a Statistical Model for the Prediction of Common Vestibular Diagnoses.: JAMA Otolaryngol Head Neck Surg. 2016 Feb 25; Authors: Friedland DR, Tarima S, Erbe C, Miles A Abstract Importance: Treatment of patients with vestibular disorders can be complex, requires lengthy clinic visit time, and uses greater clinical resources for diagnosis. A pre-encounter intake questionnaire may predict the most common disorders, allowing for more efficient allocation of resources and use of clinicians. Objective: To develop a statistical model for predicting vestibular diagnoses, pr...περισσότερα »
A Distributed Network for Social Cognition Enriched for Oxytocin Receptors.
*A Distributed Network for Social Cognition Enriched for Oxytocin Receptors.* J Neurosci. 2016 Feb 24;36(8):2517-35 Authors: Mitre M, Marlin BJ, Schiavo JK, Morina E, Norden SE, Hackett TA, Aoki CJ, Chao MV, Froemke RC Abstract UNLABELLED: Oxytocin is a neuropeptide important for social behaviors such as maternal care and parent-infant bonding. It is believed that oxytocin receptor signaling in the brain is critical for these behaviors, but it is unknown precisely when and where oxytocin receptors are expressed or which neural circuits are directly sensitive to oxytocin. To overc... περισσότερα »
Vestibular Assessment and Rehabilitation: Ten-Year Survey Trends of Audiologists' Opinions and Practice.
Related Articles *Vestibular Assessment and Rehabilitation: Ten-Year Survey Trends of Audiologists' Opinions and Practice.* J Am Acad Audiol. 2016 Feb;27(2):126-40 Authors: Nelson MD, Akin FW, Riska KM, Andresen K, Mondelli SS Abstract BACKGROUND: The past decade has yielded changes in the education and training of audiologists and technological advancements that have become widely available for clinical balance function testing. It is unclear if recent advancements in vestibular instrumentation or the transition to an AuD degree have affected audiologists' vestibular clinical pr... περισσότερα »
Postoperative Complications in Pediatric Tonsillectomy and Adenoidectomy in Ambulatory vs Inpatient Settings.
Postoperative Complications in Pediatric Tonsillectomy and Adenoidectomy in Ambulatory vs Inpatient Settings.: JAMA Otolaryngol Head Neck Surg. 2016 Feb 25; Authors: Amoils M, Chang KW, Saynina O, Wise PH, Honkanen A Abstract Importance: A large-scale review is needed to characterize the rates of airway, respiratory, and cardiovascular complications after pediatric tonsillectomy and adenoidectomy (T&A) for inpatient and ambulatory cohorts. Objective: To identify risk factors for postoperative complications stratified by age and operative facility type among children undergoing T&A....περισσότερα »
Convenient animal dosing with alzet research products
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 48 δευτερόλεπτα
Promises and pitfalls of machine scoring of the Index of Productive Syntax.
*Promises and pitfalls of machine scoring of the Index of Productive Syntax.* Clin Linguist Phon. 2016 Feb 25;:1-16 Authors: Altenberg EP, Roberts JA Abstract The AC-IPSyn computerised system for scoring the Index of Productive Syntax (IPSyn) was evaluated. Twenty language samples, ten taken at 30 months and ten of the same children at 42 months, were each scored for the IPSyn by hand and by AC-IPSyn. Point differences and point-to-point reliability were examined at the levels of the total, subscale, and individual structure scores. Points missed and erroneously given at each lev... περισσότερα »
Stereotactic radiosurgery in combination with up-front high-dose methotrexate as a first-line treatment for newly diagnosed primary central nervous system lymphoma.
[image: http:--production.springer.de-OnlineReso] Related Articles *Stereotactic radiosurgery in combination with up-front high-dose methotrexate as a first-line treatment for newly diagnosed primary central nervous system lymphoma.* J Neurooncol. 2015 Jun;123(2):237-44 Authors: Hirono S, Iwadate Y, Higuchi Y, Serizawa T, Nagano O, Matsutani T, Saeki N Abstract The efficacy of stereotactic radiosurgery (SRS) instead of whole brain radiotherapy (WBRT) following high-dose methotrexate (HD-MTX) for primary central nervous system lymphoma (PCNSL) is unclear. To clarify whether SRS i... περισσότερα »
Folate pathway gene polymorphisms and risk of childhood brain tumors: results from an Australian case-control study.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Folate pathway gene polymorphisms and risk of childhood brain tumors: results from an Australian case-control study.* Cancer Epidemiol Biomarkers Prev. 2015 Jun;24(6):931-7 Authors: Greenop KR, Scott RJ, Attia J, Bower C, de Klerk NH, Norris MD, Haber M, Jamieson SE, van Bockxmeer FM, Gottardo NG, Ashton LJ, Armstrong BK, Milne E Abstract BACKGROUND: Recent research suggests that maternal folic acid supplementation is associated with a reduced risk of childhood brain tumors (CBT); polymorphisms in folate pathway ... περισσότερα »
New perspectives on dietary-derived treatments and food safety-antinomy in a new era.
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *New perspectives on dietary-derived treatments and food safety-antinomy in a new era.* Crit Rev Food Sci Nutr. 2015;55(13):1836-59 Authors: Pan SY, Gao SH, Lin RC, Zhou SF, Dong HG, Tang MK, Yu ZL, Ko KM Abstract Despite the advances in science and technology and wide use of chemical drugs, dietary intervention (or food therapy) remains useful in preventing or treating many human diseases. A huge body of evidence shows that the dietary pattern or habit is also an important contributing factor to the development of chronic di... περισσότερα »
Mitigation of paracetamol-induced reproductive damage by chrysin in male rats via reducing oxidative stress.
*Mitigation of paracetamol-induced reproductive damage by chrysin in male rats via reducing oxidative stress.* Andrologia. 2016 Feb 24; Authors: Aksu EH, Özkaraca M, Kandemir FM, Ömür AD, Eldutar E, Küçükler S, Çomaklı S Abstract Paracetamol (PRC) is a nonsteroidal anti-inflammatory drug used widely as a painkiller for various diseases and as the symptomatic flu cure in several countries worldwide. PRC toxicity may occur under conditions of the overdose usage. Chrysin (CR) is a flavonoid that is naturally present in several plants, honey and propolis. The aim of this study was to...περισσότερα »
The VZV/IE63-specific T cell response prevents herpes zoster in fingolimod-treated patients.
*The VZV/IE63-specific T cell response prevents herpes zoster in fingolimod-treated patients.* Neurol Neuroimmunol Neuroinflamm. 2016 Apr;3(2):e209 Authors: Mathias A, Perriard G, Canales M, Vuilleumier F, Perrotta G, Schluep M, Du Pasquier R Abstract OBJECTIVE: To assess longitudinally the antiviral immune response of T cells from patients with multiple sclerosis (MS) treated with fingolimod (FTY) vs other disease-modifying treatments (DMTs). METHODS: We assessed cellular immune responses specific to influenza virus (FLU), JC virus (JCV), and varicella-zoster virus (VZV) using q... περισσότερα »
A fatal case of infection with a further reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus in Yunnan, China.
*A fatal case of infection with a further reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus in Yunnan, China.* Infect Genet Evol. 2016 Feb 18; Authors: Xu W, Li X, Bai T, Zhao X, Zhao X, Zhang Y, Guo J, Li Z, Yang L, Wang D, Shu Y PMID: 26911643 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1XPyDFA via IFTTT
Impact of Resistance to Fluconazole on Virulence and Morphological Aspects of Cryptococcus neoformans and Cryptococcus gattii Isolates.
Related Articles *Impact of Resistance to Fluconazole on Virulence and Morphological Aspects of Cryptococcus neoformans and Cryptococcus gattii Isolates.* Front Microbiol. 2016;7:153 Authors: Rossi SA, Trevijano-Contador N, Scorzoni L, Mesa-Arango AC, de Oliveira HC, Werther K, de Freitas Raso T, Mendes-Giannini MJ, Zaragoza O, Fusco-Almeida AM Abstract Cryptococcus sp. are responsible for around 1 million cases of meningitis every year. Fluconazole (FLU) is commonly used in the treatment of cryptococcosis, mainly in immunocompromised patients and the resistance is usually repor... περισσότερα »
Cross-reactivity between avian influenza A (H7N9) virus and divergent H7 subtypic- and heterosubtypic influenza A viruses.
Related Articles *Cross-reactivity between avian influenza A (H7N9) virus and divergent H7 subtypic- and heterosubtypic influenza A viruses.* Sci Rep. 2016;6:22045 Authors: Guo L, Wang D, Zhou H, Wu C, Gao X, Xiao Y, Ren L, Paranhos-Baccalà G, Shu Y, Jin Q, Wang J Abstract The number of human avian H7N9 influenza infections has been increasing in China. Understanding their antigenic and serologic relationships is crucial for developing diagnostic tools and vaccines. Here, we evaluated the cross-reactivities and neutralizing activities among H7 subtype influenza viruses and betwe...περισσότερα »
[ADJUVANTED INFLUENZA VACCINES: DATA FROM DIRECT COMPARATIVE STUDIES].
Related Articles *[ADJUVANTED INFLUENZA VACCINES: DATA FROM DIRECT COMPARATIVE STUDIES].* Zh Mikrobiol Epidemiol Immunobiol. 2015 Sep-Oct;(5):88-102 Authors: Chernikova MI, Vasiliev YM Abstract Vaccines are the cornerstone of influenza control, however available vaccines are subject to certain limitations. Adjuvanted vaccines are a promising approach, however available adjuvants have a suboptimal effectiveness and safety profile. Data from direct comparative trials are necessary for selection of optimal adjuvants among currently available and search for novel safe and effective a... περισσότερα »
[COLD-ADAPTED A/KRASNODAR/101/35/59 (H2N2) STRAIN--A PROMISING STRAIN-DONOR OF ATTENUATION FOR PROCURATION OF LIVE INFLUENZA VACCINES].
Related Articles *[COLD-ADAPTED A/KRASNODAR/101/35/59 (H2N2) STRAIN--A PROMISING STRAIN-DONOR OF ATTENUATION FOR PROCURATION OF LIVE INFLUENZA VACCINES].* Zh Mikrobiol Epidemiol Immunobiol. 2015 Sep-Oct;(5):27-32 Authors: Markushin SG, Tsfasman TM, Terekhov AV, Lisovskaya KV, Akopova II Abstract AIM: Study of ts, ca, att phenotype, immunogenicity and protective effectiveness of reassortants obtained by a way of recombination of a new influenza cold-adapted (ca) strain donor of attenuation A/Krasnodar/101/35/59 (H2N2) and virulent strain of influenza virus. MATERIALS AND METHODS: V... περισσότερα »
[Evidence under scrutiny. Neuraminidase inhibitors in severe influenza: yes or no?].
Related Articles *[Evidence under scrutiny. Neuraminidase inhibitors in severe influenza: yes or no?].* MMW Fortschr Med. 2015 Oct 8;157(17):24 Authors: Bischoff A PMID: 26759863 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1TCTuvd via IFTTT
[Knowledge and vaccination gaps before the 2015/2016 influenza seasons].
Related Articles *[Knowledge and vaccination gaps before the 2015/2016 influenza seasons].* Kinderkrankenschwester. 2015 Nov;34(11):420-1 Authors: Völker-Albert M PMID: 26710420 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1TCTwDd via IFTTT
Safety of live attenuated influenza vaccine in young people with egg allergy: multicentre prospective cohort study.
[image: http:--highwire.stanford.edu-icons-exter] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Safety of live attenuated influenza vaccine in young people with egg allergy: multicentre prospective cohort study.* BMJ. 2015;351:h6291 Authors: Turner PJ, Southern J, Andrews NJ, Miller E, Erlewyn-Lajeunesse M, SNIFFLE-2 Study Investigators Abstract STUDY QUESTION: How safe is live attenuated influenza vaccine (LAIV), which contains egg protein, in young people with egg allergy? METHODS: In this open label, phase IV intervention study, 779 young people (2-18 years) with egg... περισσότερα »
Early oral feeding after total laryngectomy: Outcome of 602 patients in one cancer center.
Related Articles *Early oral feeding after total laryngectomy: Outcome of 602 patients in one cancer center.* Auris Nasus Larynx. 2016 Feb 19; Authors: Süslü N, Şefik Hoşal A Abstract OBJECTIVE: Pharyngocutaneous fistula (PCF) is the most frequent complication after total laryngectomy. However, delayed oral feeding and inserting a nasogastric tube has been considered as a safe practice among head and neck surgeons, and there is no general agreement on the initiation of the oral intake. The aim of the study is to determine the incidence of PCF after primary total laryngectomy in ... περισσότερα »
Evaluation of stapled closure following laryngectomy for carcinoma larynx in an Indian tertiary cancer centre.
Related Articles *Evaluation of stapled closure following laryngectomy for carcinoma larynx in an Indian tertiary cancer centre.* Indian J Cancer. 2015 Jul-Sep;52(3):376-80 Authors: Babu S, Varghese BT, Iype EM, George PS, Sebastian P Abstract BACKGROUND AND AIM: Stapling devices are used for pharyngeal closure after laryngectomy for the past few decades although it has not gained wide acceptance. This study is aimed at evaluating the role of stapler in pharyngeal closure after laryngectomy. METHODS: Thirty consecutive patients who underwent stapled laryngectomy at our institutio...περισσότερα »
Anthropometric Assessment of Neck Adipose Tissue and Airway Volume Using Multidetector Computed Tomography: An Imaging Approach and Association With Overall Mortality.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Anthropometric Assessment of Neck Adipose Tissue and Airway Volume Using Multidetector Computed Tomography: An Imaging Approach and Association With Overall Mortality.* Medicine (Baltimore). 2015 Nov;94(45):e1991 Authors: Maresky HS, Sharfman Z, Ziv-Baran T, Gomori JM, Copel L, Tal S Abstract Neck adiposity tissue volume (NATV) accumulation is an indicator for metabolic syndrome and cardiovascular disease (CVD). Neck circumference is a poor measure of NATV, and a quantifier for this entity has not yet been establ... περισσότερα »
A Comparison of Different Methods to Generate Tooth Surface Models Without Applying Ionizing Radiation for Digital 3-Dimensional Image Fusion With Magnetic Resonance Imaging-Based Data of the Head and Neck Region.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *A Comparison of Different Methods to Generate Tooth Surface Models Without Applying Ionizing Radiation for Digital 3-Dimensional Image Fusion With Magnetic Resonance Imaging-Based Data of the Head and Neck Region.* J Comput Assist Tomogr. 2015 Nov-Dec;39(6):882-9 Authors: Traser L, Flügge TV, Burdumy M, Kamberger R, Richter B, Hassepass F, Korvink JG, Echternach M Abstract OBJECTIVE: The 3-dimensional display of the vocal tract and teeth is necessary in numerous clinical and scientific contexts. Due to the differ... περισσότερα »
The inaccuracy of using landmark techniques for cricothyroid membrane identification: a comparison of three techniques.
Related Articles *The inaccuracy of using landmark techniques for cricothyroid membrane identification: a comparison of three techniques.* Acad Emerg Med. 2015 Aug;22(8):908-14 Authors: Bair AE, Chima R Abstract OBJECTIVES: Successful cricothyrotomy is predicated on accurate identification of the cricothyroid membrane (CTM) by palpation of superficial anatomy. However, recent research has indicated that accuracy of the identification of the CTM can be as low as 30%, even in the hands of skilled providers. To date, there are very little data to suggest how to best identify this c...περισσότερα »
Expression of SOX9 and CDX2 in nongoblet columnar-lined esophagus predicts the detection of Barrett's esophagus during follow-up.
[image: http:--http://ift.tt/1feGv2I] Related Articles *Expression of SOX9 and CDX2 in nongoblet columnar-lined esophagus predicts the detection of Barrett's esophagus during follow-up.* Mod Pathol. 2015 May;28(5):654-61 Authors: Zhang X, Westerhoff M, Hart J Abstract The diagnosis of Barrett's esophagus in the United States requires both endoscopically evident columnar-lined esophagus and the presence of goblet cells by histology. Currently, there is no consensus on how patients with nongoblet columnar-lined esophagus should be followed. In this study, we investigated whether bi... περισσότερα »
Assessing the Validity of Transcutaneous Laryngeal Ultrasonography (TLUSG) After Thyroidectomy: What Factors Matter?
[image: http:--production.springer.de-OnlineReso] Related Articles *Assessing the Validity of Transcutaneous Laryngeal Ultrasonography (TLUSG) After Thyroidectomy: What Factors Matter?* Ann Surg Oncol. 2015;22(6):1774-80 Authors: Wong KP, Lang BH, Chang YK, Wong KC, Chow FC Abstract INTRODUCTION: Although transcutaneous laryngeal ultrasound (TLUSG) is an excellent, noninvasive way to assess vocal cord (VC) function after thyroidectomy, some patients simply have "un-assessable" or "inaccurate" examination. Our study evaluated what patient and surgical factors affected assessabilit... περισσότερα »
Cancer of the Upper Aerodigestive Tract: Assessment and Management in People Aged 16 and Over
*Cancer of the Upper Aerodigestive Tract: Assessment and Management in People Aged 16 and Over* Book. 2016 02 Authors: National Collaborating Centre for Cancer (UK) Abstract There is no single universal definition of the upper aerodigestive tract; for the purposes of this guideline, it encompasses the oral cavity, oropharynx, nasopharynx, hypopharynx, larynx, and paranasal sinuses. The vast majority of cancers at these sites are squamous cell carcinomas (National Head and Neck Cancer Audit, 2014). Some other cancers with less common histological diagnoses, such as mucosal melanom... περισσότερα »
Neoadjuvant chemotherapy and radical radiotherapy associated with cetuximab for laryngeal cancer in a pancreas and renal recipient.
Related Articles *Neoadjuvant chemotherapy and radical radiotherapy associated with cetuximab for laryngeal cancer in a pancreas and renal recipient.* Anticancer Drugs. 2016 Feb 22; Authors: Bonetta A, Bandera L, Roviello G, Cafaro I, Bottini A, Generali D Abstract The oncological treatment for advanced stage head and neck cancer is based on a combination of cisplatin and cetuximab, and radiotherapy. However, very few data are available on this multimodal approach for this type of cancer in pancreas and renal recipients. We report the case of a pancreas and renal recipient being ... περισσότερα »
Cost-Effective Surgical Management of Liver Disease Amidst a Financial Crisis.
*Cost-Effective Surgical Management of Liver Disease Amidst a Financial Crisis.* World J Surg. 2016 Feb 25; Authors: Arkadopoulos N, Gemenetzis G, Danias N, Kokoropoulos P, Koukopoulou I, Bartsokas C, Kostopanagiotou G, Smyrniotis V Abstract BACKGROUND: Intraoperative use of specialized equipment and disposables contributes to the increasing cost of modern liver surgery. As a response to the recent severe financial crisis in our country we have employed a highly standardized protocol of liver resection that minimizes intraoperative and postoperative costs. Our goal is to evaluate...περισσότερα »
Chemoprevention in Barrett's Esophagus: Current Status.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Chemoprevention in Barrett's Esophagus: Current Status.* Gastroenterol Clin North Am. 2015 Jun;44(2):391-413 Authors: Zeb MH, Baruah A, Kossak SK, Buttar NS Abstract Chemoprevention in Barrett's esophagus is currently applied only in research settings. Identifying pathways that can be targeted by safe, pharmaceutical or natural compounds is key to expanding the scope of chemoprevention. Defining meaningful surrogate markers of cancer progression is critical to test the efficacy of chemopreventive approaches. Comb... περισσότερα »
Role of Obesity in the Pathogenesis and Progression of Barrett's Esophagus.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Role of Obesity in the Pathogenesis and Progression of Barrett's Esophagus.* Gastroenterol Clin North Am. 2015 Jun;44(2):249-64 Authors: Chandar AK, Iyer PG Abstract Central obesity is involved in the pathogenesis and progression of Barrett's esophagus to esophageal adenocarcinoma. Involved are likely both mechanical and nonmechanical effects. Mechanical effects of increased abdominal fat cause disruption of the gastroesophageal reflux barrier leading to increased reflux events. Nonmechanical effects may be media... περισσότερα »
Epidemiology of Barrett's Esophagus and Esophageal Adenocarcinoma.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Epidemiology of Barrett's Esophagus and Esophageal Adenocarcinoma.* Gastroenterol Clin North Am. 2015 Jun;44(2):203-31 Authors: Runge TM, Abrams JA, Shaheen NJ Abstract Barrett's esophagus (BE) is the precursor to esophageal adenocarcinoma (EAC), a disease with increasing burden in the Western world, especially in white men. Risk factors for BE include obesity, tobacco smoking, and gastroesophageal reflux disease (GERD). EAC is the most common form of esophageal cancer in the United States. Risk factors include GE... περισσότερα »
Esophageal dysmotility is present before surgery in isolated tracheoesophageal fistula.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Esophageal dysmotility is present before surgery in isolated tracheoesophageal fistula.* J Pediatr Gastroenterol Nutr. 2015 May;60(5):642-4 Authors: Lemoine C, Aspirot A, Morris M, Faure C Abstract After surgical correction of esophageal atresia with or without tracheoesophageal fistula, esophageal body motility dysfunction has been reported in nearly all patients. Using high-resolution esophageal manometry before surgical repair in 2 children with isolated tracheoesophageal fistula, we sought to determine whethe... περισσότερα »
Management of Dysphagia in Esophageal Adenocarcinoma Patients Undergoing Neoadjuvant Chemotherapy: Can Invasive Tube Feeding be Avoided?
[image: http:--production.springer.de-OnlineReso] Related Articles *Management of Dysphagia in Esophageal Adenocarcinoma Patients Undergoing Neoadjuvant Chemotherapy: Can Invasive Tube Feeding be Avoided?* Ann Surg Oncol. 2015;22(6):1858-65 Authors: Cools-Lartigue J, Jones D, Spicer J, Zourikian T, Rousseau M, Eckert E, Alcindor T, Vanhuyse M, Asselah J, Ferri LE Abstract BACKGROUND: Neoadjuvant chemotherapy is an accepted standard for locally advanced esophagogastric junction adenocarcinoma. However, the dysphagia frequently associated with this condition may interfere with patie...περισσότερα »
[Prognostic factors of sudden sensorineural hearing loss in children].
*[Prognostic factors of sudden sensorineural hearing loss in children].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(22):1931-5 Authors: Li F, Xue X, Wang L, Yang F, Wang H, Guan J, Du W, Xiong W, Wu K, Wu M, Yin Z, Lan L, Wang D, Wang Q Abstract OBJECTIVE: The aim of this retrospective study was to analyze the recovery rate of sudden sensorineural hearing loss in children, and explore the prognostic factors in order to guide the clinical diagnosis and treatment. METHOD: A retrospective review was conducted for the prognosis of children with sudden sensorineural hea...περισσότερα »
[St. John's Wort for aura and vertigo].
Related Articles *[St. John's Wort for aura and vertigo].* MMW Fortschr Med. 2015 Sep 24;157(16):24 Authors: Fueßl HS, Stiefelhagen P PMID: 26783610 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1QhOCdX via IFTTT
EEG based evaluation of stereoscopic 3D displays for viewer discomfort.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *EEG based evaluation of stereoscopic 3D displays for viewer discomfort.* Biomed Eng Online. 2015;14:21 Authors: Malik AS, Khairuddin RN, Amin HU, Smith ML, Kamel N, Abdullah JM, Fawzy SM, Shim S Abstract BACKGROUND: Consumer preference is rapidly changing from 2D to 3D movies due to the sensational effects of 3D scenes, like those in Avatar and The Hobbit. Two 3D viewing technologies are available: active shutter glasses and passive polarized glasses. However, there are consistent report... περισσότερα »
N-acetyl-L-leucine accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *N-acetyl-L-leucine accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus.* PLoS One. 2015;10(3):e0120891 Authors: Günther L, Beck R, Xiong G, Potschka H, Jahn K, Bartenstein P, Brandt T, Dutia M, Dieterich M, Strupp M, la Fougère C, Zwergal A Abstract An acute unilateral vestibular lesion leads to a vestibular tone imbalance with nystagmus, head roll tilt and postural imbalance. These deficits gradually decrease over days to weeks d... περισσότερα »
Mesotheliomas show higher hyaluronan positivity around tumor cells than metastatic pulmonary adenocarcinomas.
*Mesotheliomas show higher hyaluronan positivity around tumor cells than metastatic pulmonary adenocarcinomas.* Histol Histopathol. 2016 Feb 25;:11740 Authors: Kari T, Ylermi S, Paavo P, Jyrki P, Reijo S, Kirsi R Abstract Hyaluronan is a unique glycosaminoglycan of the extracellular matrix, abundant in normal connective tissues but highly increased in many pathological conditions like cancer. Mesothelioma, one of the most malignant cancer types, is associated with high content of hyaluronan, with elevated levels of hyaluronan in pleural effusions and serum of the patients. Metast... περισσότερα »
TWEAK/Fn14 signaling: a promising target in intervertebral disc degeneration.
Related Articles *TWEAK/Fn14 signaling: a promising target in intervertebral disc degeneration.* Histol Histopathol. 2016 Feb 24;:11745 Authors: Liu YP, Yuan CM, Zhang SG, Hao QH, Wang QH, Zhang Z, Meng Q, Li M, Hao YD Abstract Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) is a potent chemoattractant cytokine with various biological functions, such as stimulation of angiogenesis, induction of proinflammatory cytokines, regulation of cellular proliferation and apoptosis. Therefore, it has also been implicated in several pathological processes, from cancer to ... περισσότερα »
The history and histology of bone morphogenetic protein.
Related Articles *The history and histology of bone morphogenetic protein.* Histol Histopathol. 2016 Feb 23;:11744 Authors: Murray SS, Murray EJ, Wang JC, Duarte ME Abstract Bone morphogenetic proteins are a group of structurally related proteins within the TGF-β superfamily of proteins with a diverse repertoire of functions in embryonic and adult organisms. As is apparent from the name, the members first characterized participate in bone growth, development, and remodeling. The "morphogenic" activity per se is defined as the induction of a recapitulation of endochondral bone for... περισσότερα »
Immunohistochemical expression of keratins 6, 7, 8, 14, 16, 18, 19, and MNF-116 pancytokeratin in primary and metastatic melanoma of the head and neck.
Related Articles *Immunohistochemical expression of keratins 6, 7, 8, 14, 16, 18, 19, and MNF-116 pancytokeratin in primary and metastatic melanoma of the head and neck.* Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Dec 19; Authors: Safadi RA, Bader DH, Abdullah NI, Sughayer MA Abstract OBJECTIVE: To investigate the immunohistochemical expression (IHCE) of selected keratins in primary cutaneous and mucosal melanoma (pM), and metastatic melanoma (metsM) of the head and neck and to compare their expression to a group of undifferentiated/poorly differentiated tumors of the same... περισσότερα »
Red exophytic mass of the maxillary anterior gingiva.
Related Articles *Red exophytic mass of the maxillary anterior gingiva.* Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Nov 22; Authors: Aljadeff L, Fisher CA, Wolf SL, Byrd KM, Curtis W, Ward BB, Munz SM, Fullen DR, McHugh JB, Danciu TE PMID: 26906949 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1oMkiht via IFTTT
[Review of ear and nose and throat involvement in IgG4-RD].
*[Review of ear and nose and throat involvement in IgG4-RD].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(22):2015-8 Authors: Tao X, Liu C, Song B Abstract IgG4-related disease (IgG4-RD) is a newly recognized disease entity. IgG4-RD is characterized by a single or multiple masses in one or more organs; a lymphoplasmacytic infiltrate with a high percentage of plasma cells within the lesion staining for IgG4; a peculiar pattern of fibrosis known as "storiform" fibrosis; and elevated serum IgG4 concentrations. IgG4-RD can occur in various organs, including pancreas, k...περισσότερα »
[Intubation treatment of acute laryngeal obstruction: a case report].
*[Intubation treatment of acute laryngeal obstruction: a case report].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(22):2014 Authors: Guo X, Liu S, Li H Abstract Acute laryngeal obstruction is one of the most common diseases in Department of ENT, and it can cause suffocation without prompt treatment. Methods by using Nasopharyngofiberoscope guided tracheal intubation treatment of a case of acute laryngeal obstruction patients in a timely manner. This method is well tolerated, less trauma, high success rate, in the shortest time to improve the patient's ventilation,... περισσότερα »
[Three cases of benign positional paroxysmal vertigo in pregnant women].
*[Three cases of benign positional paroxysmal vertigo in pregnant women].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(22):2012-3 Authors: Guo P, Li J, Zhang H Abstract BPPV is the most common cause of dizziness in adults, and the symptoms, causes, behavior of adult patients are clearly defined. Pregnant woman may also suffer from BPPV. To our knowledge, there are few reports on BPPV in pregnant women. In this paper, the clinical characteristics and results of 3 pregnant women with BPPV are reported. PMID: 26911074 [PubMed - in process] from Head and Neck on PubM... περισσότερα »
[Two rare case report of maxillary sinus foreign body].
*[Two rare case report of maxillary sinus foreign body].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(22):2011-2 Authors: Wang Y, Zhu J, Ma Z Abstract The maxillary sinus is the largest paranasal sinuses. Foreign bodies of nosal sinus can caused by car accidents, firearm attacks, or iatrogeniccause. We reported two rare cases of foreign body of pulp needle and loach. The clinical manifestations might include facial numbness, facial paresthesia, swelling, nasal congestion, facial pain, eye discomfort, limited mouth opening and relapse and etc. Both CT scan and the ...περισσότερα »
[Treatment of cicatricial external auditory canal atresia after burn].
*[Treatment of cicatricial external auditory canal atresia after burn].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(22):2009-10 Authors: Dong B, Wu L, Chen L PMID: 26911072 [PubMed - in process] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1KPOQIW via IFTTT
Stereotactic radiosurgery in combination with up-front high-dose methotrexate as a first-line treatment for newly diagnosed primary central nervous system lymphoma.
[image: http:--production.springer.de-OnlineReso] Related Articles *Stereotactic radiosurgery in combination with up-front high-dose methotrexate as a first-line treatment for newly diagnosed primary central nervous system lymphoma.* J Neurooncol. 2015 Jun;123(2):237-44 Authors: Hirono S, Iwadate Y, Higuchi Y, Serizawa T, Nagano O, Matsutani T, Saeki N Abstract The efficacy of stereotactic radiosurgery (SRS) instead of whole brain radiotherapy (WBRT) following high-dose methotrexate (HD-MTX) for primary central nervous system lymphoma (PCNSL) is unclear. To clarify whether SRS i... περισσότερα »
Folate pathway gene polymorphisms and risk of childhood brain tumors: results from an Australian case-control study.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Folate pathway gene polymorphisms and risk of childhood brain tumors: results from an Australian case-control study.* Cancer Epidemiol Biomarkers Prev. 2015 Jun;24(6):931-7 Authors: Greenop KR, Scott RJ, Attia J, Bower C, de Klerk NH, Norris MD, Haber M, Jamieson SE, van Bockxmeer FM, Gottardo NG, Ashton LJ, Armstrong BK, Milne E Abstract BACKGROUND: Recent research suggests that maternal folic acid supplementation is associated with a reduced risk of childhood brain tumors (CBT); polymorphisms in folate pathway ... περισσότερα »
New perspectives on dietary-derived treatments and food safety-antinomy in a new era.
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *New perspectives on dietary-derived treatments and food safety-antinomy in a new era.* Crit Rev Food Sci Nutr. 2015;55(13):1836-59 Authors: Pan SY, Gao SH, Lin RC, Zhou SF, Dong HG, Tang MK, Yu ZL, Ko KM Abstract Despite the advances in science and technology and wide use of chemical drugs, dietary intervention (or food therapy) remains useful in preventing or treating many human diseases. A huge body of evidence shows that the dietary pattern or habit is also an important contributing factor to the development of chronic di... περισσότερα »
Chondroblastoma of the temporomandibular joint lateral capsule: a case report.
Related Articles *Chondroblastoma of the temporomandibular joint lateral capsule: a case report.* Cranio. 2015 Oct;33(4):306-11 Authors: Kim SM, Hong SW, Ryu da J, Huh JK Abstract AIM: Chondroblastoma is a rare, benign bone tumor that accounts for approximately 1% of all primary bone tumors. Chondroblastoma that occurs at the temporomandibular joint can exhibit symptoms similar to those associated with other temporomandibular disorders. This case study aims to present an eight-year followup of chondroblastoma occurring at the temporomandibular joint. METHODOLOGY: The patient pre... περισσότερα »
[Molecular analysis of childhood B-acute lymphoblastic leukemia: Identification and prognosis of rare breakpoints].
Related Articles *[Molecular analysis of childhood B-acute lymphoblastic leukemia: Identification and prognosis of rare breakpoints].* Mol Biol (Mosk). 2015 Nov-Dec;49(6):944-8 Authors: Kumar D, Panigrahi MK, Saikia KK, Kapoor G, Mehta A Abstract Acute lymphoblastic leukaemia (ALL) is the most common subtype of childhood cancer. Detection of a specific gene rearrangement allows the identification of prognostically relevant subgroups in childhood B-ALL. There are four common gene rearrangements which are widely studied to see prognostical values (TEL-AML1, BCR-ABL, E2A-PBX1, MLL-A... περισσότερα »
Differential Expression of AMPA Subunits Induced by NMDA Intrahippocampal Injection in Rats.
*Differential Expression of AMPA Subunits Induced by NMDA Intrahippocampal Injection in Rats.* Front Neurosci. 2016;10:32 Authors: Fachim HA, Pereira AC, Iyomasa-Pilon MM, Rosa ML Abstract Glutamate is involved in excitotoxic mechanisms by interacting with different receptors. Such interactions result in neuronal death associated with several neurodegenerative disorders of the central nervous system (CNS). The aim of this work was to study the time course of changes in the expression of GluR1 and GluR2 subunits of glutamate amino-acid-3-hydroxy-5-methyl-isoxazol-4-propionic acid ... περισσότερα »
Classification of Eye Fixation Related Potentials for Variable Stimulus Saliency.
*Classification of Eye Fixation Related Potentials for Variable Stimulus Saliency.* Front Neurosci. 2016;10:23 Authors: Wenzel MA, Golenia JE, Blankertz B Abstract OBJECTIVE: Electroencephalography (EEG) and eye tracking can possibly provide information about which items displayed on the screen are relevant for a person. Exploiting this implicit information promises to enhance various software applications. The specific problem addressed by the present study is that items shown in real applications are typically diverse. Accordingly, the saliency of information, which allows to ... περισσότερα »
Editorial: Ontogeny and Phylogeny of Brain Barrier Mechanisms.
Related Articles *Editorial: Ontogeny and Phylogeny of Brain Barrier Mechanisms.* Front Neurosci. 2016;10:41 Authors: Stolp HB, Liddelow SA, Saunders NR PMID: 26909020 [PubMed] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1RsjqYn via IFTTT
Skin Sympathetic Nerve Activity is Modulated during Slow Sinusoidal Linear Displacements in Supine Humans.
Related Articles *Skin Sympathetic Nerve Activity is Modulated during Slow Sinusoidal Linear Displacements in Supine Humans.* Front Neurosci. 2016;10:39 Authors: Bolton PS, Hammam E, Kwok K, Macefield VG Abstract Low-frequency sinusoidal linear acceleration (0.08 Hz, ±4 mG) modulates skin sympathetic nerve activity (SSNA) in seated subjects (head vertical), suggesting that activation of the utricle in the peripheral vestibular labyrinth modulates SSNA. The aim of the current study was to determine whether SSNA is also modulated by input from the saccule. Tungsten microelectrodes...περισσότερα »
Generalized Poincaré Plots-A New Method for Evaluation of Regimes in Cardiac Neural Control in Atrial Fibrillation and Healthy Subjects.
Related Articles *Generalized Poincaré Plots-A New Method for Evaluation of Regimes in Cardiac Neural Control in Atrial Fibrillation and Healthy Subjects.* Front Neurosci. 2016;10:38 Authors: Platiša MM, Bojić T, Pavlović SU, Radovanović NN, Kalauzi A Abstract Classical Poincaré plot is a standard way to measure nonlinear regulation of cardiovascular control. In our work we propose a generalized form of Poincaré plot where we track correlation between the duration of j preceding and k next RR intervals. The investigation was done in healthy subjects and patients with atrial fibri... περισσότερα »
Ketamine-Based Anesthetic Protocols and Evoked Potential Monitoring: A Risk/Benefit Overview.
Related Articles *Ketamine-Based Anesthetic Protocols and Evoked Potential Monitoring: A Risk/Benefit Overview.* Front Neurosci. 2016;10:37 Authors: Stoicea N, Versteeg G, Florescu D, Joseph N, Fiorda-Diaz J, Navarrete V, Bergese SD Abstract Since its discovery, ketamine, a non-competitive N-methyl D-aspartate (NMDA) receptor antagonist related to phencyclidine, has been linked to multiple adverse reactions sometimes described as "out of body" and "near death experiences," including emergence phenomena, delusions, hallucinations, delirium, and confusion. Due to these effects, ke... περισσότερα »
Editorial: How, and Why, Does Spatial-Hearing Ability Differ among Listeners? What is the Role of Learning and Multisensory Interactions?
Related Articles *Editorial: How, and Why, Does Spatial-Hearing Ability Differ among Listeners? What is the Role of Learning and Multisensory Interactions?* Front Neurosci. 2016;10:36 Authors: Andéol G, Simpson BD PMID: 26909016 [PubMed] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1Rsjqrq via IFTTT
Event-Based Computation of Motion Flow on a Neuromorphic Analog Neural Platform.
Related Articles *Event-Based Computation of Motion Flow on a Neuromorphic Analog Neural Platform.* Front Neurosci. 2016;10:35 Authors: Giulioni M, Lagorce X, Galluppi F, Benosman RB Abstract Estimating the speed and direction of moving objects is a crucial component of agents behaving in a dynamic world. Biological organisms perform this task by means of the neural connections originating from their retinal ganglion cells. In artificial systems the optic flow is usually extracted by comparing activity of two or more frames captured with a vision sensor. Designing artificial mot... περισσότερα »
Toll-Like Receptor 4 Deficiency Impairs Motor Coordination.
Related Articles *Toll-Like Receptor 4 Deficiency Impairs Motor Coordination.* Front Neurosci. 2016;10:33 Authors: Zhu JW, Li YF, Wang ZT, Jia WQ, Xu RX Abstract The cerebellum plays an essential role in balance and motor coordination. Purkinje cells (PCs) are the sole output neurons of the cerebellar cortex and are critical for the execution of its functions, including motor coordination. Toll-like receptor (TLR) 4 is involved in the innate immune response and is abundantly expressed in the central nervous system; however, little is known about its role in cerebellum-related mot... περισσότερα »
IJMS, Vol. 17, Pages 299: Nutrigenetics and Nutrimiromics of the Circadian System: The Time for Human Health
Even though the rhythmic oscillations of life have long been known, the precise molecular mechanisms of the biological clock are only recently being explored. Circadian rhythms are found in virtually all organisms and affect our lives. Thus, it is not surprising that the correct running of this clock is essential for cellular functions and health. The circadian system is composed of an intricate network of genes interwined in an intrincated transcriptional/translational feedback loop. The precise oscillation of this clock is controlled by the circadian genes that, in turn, regulat... περισσότερα »
IJMS, Vol. 17, Pages 295: Genome Editing in C. elegans and Other Nematode Species
Caenorhabditis elegans, a 1 mm long free-living nematode, is a popular model animal that has been widely utilized for genetic investigations of various biological processes. Characteristic features that make C. elegans a powerful model of choice for eukaryotic genetic studies include its rapid life cycle (development from egg to adult in 3.5 days at 20 °C), well-annotated genome, simple morphology (comprising only 959 somatic cells in the hermaphrodite), and transparency (which facilitates non-invasive fluorescence observations). However, early approaches to introducing mutations ... περισσότερα »
IJMS, Vol. 17, Pages 289: Erythropoietin Ameliorates Neonatal Hypoxia-Ischemia-Induced Neurobehavioral Deficits, Neuroinflammation, and Hippocampal Injury in the Juvenile Rat
The hematopoietic growth factor erythropoietin (EPO) has been shown to be neuroprotective against hypoxia-ischemia (HI) in Postnatal Day 7 (P7)–P10 or adult animal models. The current study was aimed to determine whether EPO also provides long-lasting neuroprotection against HI in P5 rats, which is relevant to immature human infants. Sprague-Dawley rats at P5 were subjected to right common carotid artery ligation followed by an exposure to 6% oxygen with balanced nitrogen for 1.5 h. Human recombinant EPO (rEPO, at a dose of 5 units/g) was administered intraperitoneally one hour bef... περισσότερα »
IJMS, Vol. 17, Pages 292: Silicon-Doped Titanium Dioxide Nanotubes Promoted Bone Formation on Titanium Implants
While titanium (Ti) implants have been extensively used in orthopaedic and dental applications, the intrinsic bioinertness of untreated Ti surface usually results in insufficient osseointegration irrespective of the excellent biocompatibility and mechanical properties of it. In this study, we prepared surface modified Ti substrates in which silicon (Si) was doped into the titanium dioxide (TiO2) nanotubes on Ti surface using plasma immersion ion implantation (PIII) technology. Compared to TiO2 nanotubes and Ti alone, Si-doped TiO2 nanotubes significantly enhanced the expression of... περισσότερα »
IJMS, Vol. 17, Pages 297: Identification of Human Adenovirus in Respiratory Samples with Luminex Respiratory Virus Panel Fast V2 Assay and Real-Time Polymerase Chain Reaction
In order to compare the last version of the Respiratory Virus Panel (RVP) Fast assay for human Adenovirus (hAdv) detection with a specific real-time polymerase chain reaction (qPCR), which is considered the gold standard for hAdv detection, nasopharyngeal samples collected from 309 children (age range, four months to eight years) with respiratory tract infection were tested using the RVP Fast v2 assay (Luminex Molecular Diagnostics, Inc., Toronto, ON, Canada) and a specific TaqMan qPCR to identify hAdv DNA. The RVP Fast v2 assay detected 30/61 (49.2%) hAdv infections that had been ...περισσότερα »
Sensors, Vol. 16, Pages 295: Outage Performance Analysis of Relay Selection Schemes in Wireless Energy Harvesting Cooperative Networks over Non-Identical Rayleigh Fading Channels
In this paper, we study relay selection in decode-and-forward wireless energy harvesting cooperative networks. In contrast to conventional cooperative networks, the relays harvest energy from the source's radio-frequency radiation and then use that energy to forward the source information. Considering power splitting receiver architecture used at relays to harvest energy, we are concerned with the performance of two popular relay selection schemes, namely, partial relay selection (PRS) scheme and optimal relay selection (ORS) scheme. In particular, we analyze the system performanc... περισσότερα »
IJMS, Vol. 17, Pages 252: New Strategies and Methods to Study Interactions between Tobacco Mosaic Virus Coat Protein and Its Inhibitors
Studies of the targets of anti-viral compounds are hot topics in the field of pesticide research. Various efficient anti-TMV (Tobacco Mosaic Virus) compounds, such as Ningnanmycin (NNM), Antofine (ATF), Dufulin (DFL) and Bingqingxiao (BQX) are available. However, the mechanisms of the action of these compounds on targets remain unclear. To further study the mechanism of the action of the anti-TMV inhibitors, the TMV coat protein (TMV CP) was expressed and self-assembled into four-layer aggregate disks in vitro, which could be reassembled into infectious virus particles with TMV RNA... περισσότερα »
Toxins, Vol. 8, Pages 57: Aflatoxin M1 in Cow’s Milk: Method Validation for Milk Sampled in Northern Italy
Aflatoxins (AFs) are mycotoxins produced by some species of Aspergillus. In dairy cows, ingested AFB1 is metabolized into carcinogenic AFM1 which is eliminated through milk, thus posing a risk for consumer health. Here we describe the set, validation, and application of screening (ELISA) and confirmatory (HPLC) tests carried out on milk samples collected through official control of mycotoxin levels in northern Italy over a three-year period (2012–2014). The limit of detection (LOD) was set at 5 ppt and 2 ppt for ELISA and HPLC, respectively, and the limit of quantification (LOQ) wa... περισσότερα »
IJGI, Vol. 5, Pages 23: Modellingthe Relationship between the Gross Domestic Product and Built-Up Area Using Remote Sensing and GIS Data: A Case Study of Seven Major Cities in Canada
City/regional authorities are responsible for designing and structuring the urban morphology based on the desired land use activities. One of the key concerns regarding urban planning is to establish certain development goals, such as the real gross domestic product (GDP). In Canada, the gross national income (GNI) mainly relies on the mining and manufacturing industries. In order to estimate the impact of city development, this study aims to utilize remote sensing and Geographic Information System (GIS) techniques to assess the relationship between the built-up area and the repor... περισσότερα »
IJMS, Vol. 17, Pages 269: Nutritional Signaling Regulates Vitellogenin Synthesis and Egg Development through Juvenile Hormone in Nilaparvata lugens (Stål)
Insect female reproduction which comprises the synthesis of vitellogenein (Vg) in the fat body and its incorporation into developing oocytes, needs a large amount of energy and food resources. Our previous studies found that juvenile hormone (JH) regulates vitellogenesis in the brown planthopper, Nilaparvata lugens. Here, we report on the role of JH in nutrient-regulated Vg synthesis and egg development. We first cloned the genes coding for juvenile hormone acid methyltransferase (JHAMT) which is involved in JH biosynthesis and methoprene-tolerant (Met) for JH action. Amino acids (... περισσότερα »
IJERPH, Vol. 13, Pages 265: Lower Prevalence of Atopic Dermatitis and Allergic Sensitization among Children and Adolescents with a Two-Sided Migrant Background
In industrialized countries atopic diseases have been reported to be less likely in children and adolescents with a migrant background compared to non-migrants. This paper aimed at both examining and comparing prevalence of asthma, allergic rhinoconjunctivitis and atopic dermatitis and allergic sensitization to specific IgE antibodies in children and adolescents with and without a migrant background. Using data of the population-based German Health Interview and Examination Survey for children and adolescents (KiGGS;n = 17,450; 0–17 years), lifetime and 12-month prevalence of atopi... περισσότερα »
IJMS, Vol. 17, Pages 293: How to Study Biofilms after Microbial Colonization of Materials Used in Orthopaedic Implants
Over the years, various techniques have been proposed for the quantitative evaluation of microbial biofilms. Spectrophotometry after crystal violet staining is a widespread method for biofilm evaluation, but several data indicate that it does not guarantee a good specificity, although it is rather easy to use and cost saving. Confocal laser microscopy is one of the most sensitive and specific tools to study biofilms, and it is largely used for research. However, in some cases, no quantitative measurement of the matrix thickness or of the amount of embedded microorganisms has been ... περισσότερα »
IJERPH, Vol. 13, Pages 259: Risk Assessment of Fluoride Intake from Tea in the Republic of Ireland and its Implications for Public Health and Water Fluoridation
The Republic of Ireland (RoI) is the only European Country with a mandatory national legislation requiring artificial fluoridation of drinking water and has the highest per capita consumption of black tea in the world. Tea is a hyperaccumulator of fluoride and chronic fluoride intake is associated with multiple negative health outcomes. In this study, fifty four brands of the commercially available black tea bag products were purchased and the fluoride level in tea infusions tested by an ion-selective electrode method. The fluoride content in all brands tested ranged from 1.6 to 6.... περισσότερα »
Sustainability, Vol. 8, Pages 212: Comparative Life Cycle Assessment (LCA) of Two On-Site Small-Scale Activated Sludge Total Oxidation Systems in Plastic and Vibrated Reinforced Concrete
This study proposes a comparison of the environmental impacts calculated with the Life Cycle Assessment (LCA) methodology of two on-site small-scale activated sludge total oxidation systems in linear low-density polyethylene (LLDPE) and vibrated reinforced concrete (VRC). The plants were designed to ensure a treatment capacity of 5, 10, 20 and 30 equivalent inhabitants (PE). The main aim of the study was to evaluate the incidence of construction, disposal and operation phases on the total impacts evaluated with three different methods: ReCiPe 2008, Ecological Footprint and IPCC 20...περισσότερα »
Innate immune landscape in glioblastoma patient tumours
Glioblastoma is an extremely aggressive brain tumour with limited treatment options. Recent progress in using immunotherapy-based treatment options in other tumour types has spurred interest in developing approaches that might be effective in this… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1WNujp1 via IFTTT
Researchers build powerful 3-D microscope, create images of cancer cells
UT Southwestern Medical Center researchers have designed and built a microscope capable of creating high-resolution, 3-D images of living cancer cells in realistic, controllable microenvironments. «There is no microscope that allows us to look at living… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1oMnjhU via IFTTT
Efficacy and safety of secukinumab in patients with generalized pustular psoriasis: A 52-week analysis from phase III open-label multicenter Japanese study
Abstract Generalized pustular psoriasis (GPP) is a severe inflammatory skin disease characterized by the presence of sterile pustules covering almost the entire body and systemic symptoms such as fever. Secukinumab, a fully human-recombinant anti-interleukin-17A monoclonal antibody was indicated for psoriasis vulgaris and psoriatic arthritis in Japan but is not yet investigated for GPP. In this… Continue reading Efficacy and safety of secukinumab in patients with generalized pustular psoriasis: A 52-week analysis from phase III open-label multicenter Japanese study
Cancer’s «fingerprints» may give clues to tumour growth, say @OfficialUoM scientists: https://t.co/pTPf9tcKvu https://t.co/9bsQHhhyBx
Cancer’s «fingerprints» may give clues to tumour growth, say @OfficialUoM scientists: https://t.co/pTPf9tcKvu https://t.co/9bsQHhhyBx from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/703178071541551104 via IFTTT
We are hosting a prostate cancer symposium in Buenos Aires next month – learn more here https://t.co/5gt9ygj5ys https://t.co/uo8omUFKzU
We are hosting a prostate cancer symposium in Buenos Aires next month – learn more here https://t.co/5gt9ygj5ys https://t.co/uo8omUFKzU from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/703167667025235968 via IFTTT
RT @ecancer_espanol : Excelente nivel Científico y académico en el COE XII #COEXII ecancer presente filmando y apoyando este Congreso! https…
RT @ecancer_espanol : Excelente nivel Científico y académico en el COE XII #COEXII ecancer presente filmando y apoyando este Congreso! https… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/703174106900877312 via IFTTT
Viruses, Vol. 8, Pages 63: Retargeting Strategies for Oncolytic Herpes Simplex Viruses
Most of the oncolytic herpes simplex viruses (HSVs) exhibit a high safety profile achieved through attenuation. They carry defects in virulence proteins that antagonize host cell response to the virus, including innate response, apoptosis, authophagy, and depend on tumor cell proliferation. They grow robustly in cancer cells, provided that these are deficient in host cell… Continue reading Viruses, Vol. 8, Pages 63: Retargeting Strategies for Oncolytic Herpes Simplex Viruses
Transcatheter valve implantation for calcific mitral valve disease
Key Points Transcatheter treatment of calcific mitral valve disease with commercially available balloon-expandable valves is feasible Current clinical outcomes are suboptimal, consequently this should be considered only in severely symptomatic patients without other options Purpose-specific mitral valves may allow for this therapy to achieve its full potential from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1S5CFJn via… Continue reading Transcatheter valve implantation for calcific mitral valve disease
Thrombin inhibition during PCI in heart failure patients
Key Points In this retrospective analysis, CHF patients undergoing PCI had a decrease in mortality, bleeding, and transfusion as well as decreased length of stay and hospital cost when bivalirudin was used when compared to heparin. This study suggests bivalirudin may be the preferred anticoagulant for patients with CHF undergoing PCI. Confirmation of these data… Continue reading Thrombin inhibition during PCI in heart failure patients
Acute kidney injury after TAVI: Predict, detect, and prevent
Key Points Acute kidney injury (AKI) is frequently observed immediately after transcatheter aortic valve implantation (TAVI). Both classifications, the RIFLE (the Risk, Injury, Failure, Loss, and End-stage Kidney) and the KDIGO (Kidney Disease: Improving Global Outcomes) from the VARC-2 (Valve Academic Research Consortium-2) are fairly interchangeable and performed well as clinical predictors of all-cause mortality.… Continue reading Acute kidney injury after TAVI: Predict, detect, and prevent
Higher prevalence of autoimmune diseases and longer spells of vertigo in patients affected with familial Ménière's disease: A clinical comparison of familial and sporadic Ménière's disease.
[image: http:--pubs.asha.org-images-b_pubmed_ful] Related Articles *Higher prevalence of autoimmune diseases and longer spells of vertigo in patients affected with familial Ménière's disease: A clinical comparison of familial and sporadic Ménière's disease.* Am J Audiol. 2014 Jun;23(2):232-7 Authors: Hietikko E, Sorri M, Männikkö M, Kotimäki J Abstract PURPOSE This study compared clinical features, predisposing factors, and concomitant diseases between sporadic and familial Ménière's disease (MD). METHOD Retrospective chart review and postal questionnaire were used. Participants ... περισσότερα »
Higher prevalence of autoimmune diseases and longer spells of vertigo in patients affected with familial Ménière's disease: A clinical comparison of familial and sporadic Ménière's disease.
[image: http:--pubs.asha.org-images-b_pubmed_ful] Related Articles *Higher prevalence of autoimmune diseases and longer spells of vertigo in patients affected with familial Ménière's disease: A clinical comparison of familial and sporadic Ménière's disease.* Am J Audiol. 2014 Jun;23(2):232-7 Authors: Hietikko E, Sorri M, Männikkö M, Kotimäki J Abstract PURPOSE This study compared clinical features, predisposing factors, and concomitant diseases between sporadic and familial Ménière's disease (MD). METHOD Retrospective chart review and postal questionnaire were used. Participants w... περισσότερα »
Cerebral Processing of Emotionally Loaded Acoustic Signals by Tinnitus Patients
This exploratory study determined the activation pattern in nonauditory brain areas in response to acoustic, emotionally positive, negative or neutral stimuli presented to tinnitus patients and control subjects. Ten patients with chronic tinnitus and without measurable hearing loss and 13 matched control subjects were included in the study and subjected to fMRI with a 1.5-tesla scanner. During the scanning procedure, acoustic stimuli of different emotional value were presented to the subjects. Statistical analyses were performed using statistical parametric mapping (SPM 99). The act... περισσότερα »
