Wernicke’s encephalopathy after sleeve gastrectomy: Literature review.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Wernicke’s encephalopathy after sleeve gastrectomy: Literature review. Int J Surg Case Rep. 2016 Jan 22;20:92-95 Authors: Pardo-Aranda F, Perez-Romero N, Osorio J, Rodriguez-Santiago J, Muñoz E, Puértolas N, Veloso E Abstract OBJECTIVE: To describe a case of Wernicke’s encephalopathy after laparoscopic sleeve gastrectomy. SETTING: Emergency Department and gastrointestinal surgery department. CASE REPORT: A 20-year-old man […]
Primary versus secondary achalasia: A diagnostic conundrum.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Related Articles Primary versus secondary achalasia: A diagnostic conundrum. Trop Gastroenterol. 2015 Apr-Jun;36(2):86-95 Authors: Gupta P, Debi U, Sinha SK, Thapa BR, Prasad K Abstract A coherent distinction between primary and secondary achalasia is considerably important to clinicians. This is because the therapeutic interventions for the two are entirely different. Whilst pneumatic dilation is the […]
TRANSIENT PSEUDOBULBAR SYNDROME IN UNILATERAL FRONTAL OPERCULAR INFARCTS.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Related Articles [TRANSIENT PSEUDOBULBAR SYNDROME IN UNILATERAL FRONTAL OPERCULAR INFARCTS]. Ideggyogy Sz. 2015 Sep 30;68(9-10):339-45 Authors: Rózsa A, Torák Gyongyi, Nagy É, Kovács K, Gács G Abstract The classic anterior (frontal) opercular syndrome (Foix-Chavany-Marie sy.) is a cortical pseudobulbar palsy mainly due to bilateral lesions of anterior brain operculum. In 2000 the authors had a […]
Esophageal mucosal resection versus esophagectomy: a comparative study of surgical results in patients with advanced megaesophagus.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Related Articles Esophageal mucosal resection versus esophagectomy: a comparative study of surgical results in patients with advanced megaesophagus. Arq Bras Cir Dig. 2015;28(1):28-31 Authors: de Oliveira GC, da Rocha RL, Coelho-Neto Jde S, Terciotti-Junior V, Lopes LR, Andreollo NA Abstract BACKGROUND: The surgical treatment of advanced megaesophagus has no consensus, being esophagectomy the more commonly […]
Minimal endoscopic changes in non-erosive reflux disease.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Related Articles Minimal endoscopic changes in non-erosive reflux disease. Arq Bras Cir Dig. 2015;28(1):20-3 Authors: Ratin AC, Orso IR Abstract BACKGROUND: Gastroesophageal reflux disease is an increasingly common condition worldwide causing a considerable economic impact. More than half the patients with clinical symptoms of reflux disease display no mucosal erosions on esophagogastroduodenoscopy, making it impossible […]
Clinical, metabolic, and psychological characteristics in patients with gastroesophageal reflux disease overlap with irritable bowel syndrome.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Related Articles Clinical, metabolic, and psychological characteristics in patients with gastroesophageal reflux disease overlap with irritable bowel syndrome. Eur J Gastroenterol Hepatol. 2015 May;27(5):516-22 Authors: Hsu CS, Liu TT, Wen SH, Wang CC, Yi CH, Chen JH, Lei WY, Orr WC, Fabio P, Chen CL Abstract OBJECTIVES: Gastroesophageal reflux disease (GERD) and irritable bowel syndrome […]
Toxic cerebellar syndrome due to methotrexate.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Related Articles Toxic cerebellar syndrome due to methotrexate. Pract Neurol. 2015 Jun;15(3):214-5 Authors: Kinzel O, Verma RK, Wiest R, Mattle HP PMID: 25814514 [PubMed – indexed for MEDLINE] from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1Sq1SPT via IFTTT
Food allergy preceded by contact urticaria due to the same food
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 λεπτό
: Involvement of epicutaneous sensitization in food allergy via ScienceDirect Search: baker’s asthma *Source:*Allergology International, Volume 64, Issue 1 Author(s): Naoko Inomata, Mayumi Nagashima, Amiko Hakuta, Michiko Aihara BackgroundThere have recently been reports suggesting that sensitization to food allergens may occur outside the intestinal tract, especially through the skin. To clarify the role of epicutaneous sensitization in food allergy, we investigated the clinical characteristics of adult patients with food allergies preceded by contact urticaria due to the same foods.M... περισσότερα »
A thin line between Meniere's disease and spontaneous intracranial hypotension syndrome.
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 λεπτό
*A thin line between Meniere's disease and spontaneous intracranial hypotension syndrome.* Med Glas (Zenica). 2016 Feb 1;13(1):31-5 Authors: Botica I, Vrca A, Špero M, Šubarić M, Carić T, Vrca Botica M, Kovačić J, Makaruha K, Roglić A Abstract Aim To point out the similarity of Meniere disease and spontaneous intracranial hypotension and difference of their treatment. Methods A case of a 54-year-old male patient with previously diagnosed Meniere's disease and newly diagnosed spontaneous intracranial hypotension syndrome is presented. Additional neuroradiological examination, Brai... περισσότερα »
Temporal-spatial gait parameters and neurodevelopment in very-low-birth-weight preterm toddlers at 18–22 months
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 λεπτό
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Katelyn Cahill-Rowley, Jessica Rose Children born preterm with very-low birth-weight (VLBW) have increased risk of motor impairment. Early identification of impairment guides treatment to improve long-term function. Temporal-spatial gait parameters are an easily-recorded assessment of gross motor function. The objective of this study was to characterize preterm toddlers’ gait and its relationship with neurodevelopment. Velocity, cycle time, step width, step length and time asymmetry, %stance, %single-limb suppo... περισσότερα »
Load distribution and postural changes in young adults when wearing a traditional backpack versus the BackTpack
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 λεπτό
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Kimberly D. Dahl, He Wang, Jennifer K. Popp, D. Clark Dickin Backpacks lead to poor posture due to the posterior placement of the load, which overtime may contribute to low back pain and musculoskeletal complications. This study examined postural and load distribution differences between a traditional backpack (BP) and a nontraditional backpack (BTP) in a young adult population. Using a 3D motion analysis system, 24 healthy young adults (22.5±2.5years, 12 male) completed both static stance and walking trials on... περισσότερα »
Temporal-spatial gait parameters and neurodevelopment in very-low-birth-weight preterm toddlers at 18–22 months
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 λεπτό
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Katelyn Cahill-Rowley, Jessica Rose Children born preterm with very-low birth-weight (VLBW) have increased risk of motor impairment. Early identification of impairment guides treatment to improve long-term function. Temporal-spatial gait parameters are an easily-recorded assessment of gross motor function. The objective of this study was to characterize preterm toddlers’ gait and its relationship with neurodevelopment. Velocity, cycle time, step width, step length and time asymmetry, %stance, %single-limb suppo... περισσότερα »
Load distribution and postural changes in young adults when wearing a traditional backpack versus the BackTpack
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 λεπτό
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Kimberly D. Dahl, He Wang, Jennifer K. Popp, D. Clark Dickin Backpacks lead to poor posture due to the posterior placement of the load, which overtime may contribute to low back pain and musculoskeletal complications. This study examined postural and load distribution differences between a traditional backpack (BP) and a nontraditional backpack (BTP) in a young adult population. Using a 3D motion analysis system, 24 healthy young adults (22.5±2.5years, 12 male) completed both static stance and walking trials on... περισσότερα »
Temporal-spatial gait parameters and neurodevelopment in very-low-birth-weight preterm toddlers at 18–22 months
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 λεπτό
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Katelyn Cahill-Rowley, Jessica Rose Children born preterm with very-low birth-weight (VLBW) have increased risk of motor impairment. Early identification of impairment guides treatment to improve long-term function. Temporal-spatial gait parameters are an easily-recorded assessment of gross motor function. The objective of this study was to characterize preterm toddlers’ gait and its relationship with neurodevelopment. Velocity, cycle time, step width, step length and time asymmetry, %stance, %single-limb suppo... περισσότερα »
Load distribution and postural changes in young adults when wearing a traditional backpack versus the BackTpack
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 λεπτό
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Kimberly D. Dahl, He Wang, Jennifer K. Popp, D. Clark Dickin Backpacks lead to poor posture due to the posterior placement of the load, which overtime may contribute to low back pain and musculoskeletal complications. This study examined postural and load distribution differences between a traditional backpack (BP) and a nontraditional backpack (BTP) in a young adult population. Using a 3D motion analysis system, 24 healthy young adults (22.5±2.5years, 12 male) completed both static stance and walking trials on... περισσότερα »
Common food allergens and their IgE-binding epitopes
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
Common food allergens and their IgE-binding epitopes via ScienceDirect Search: baker’s asthma *Source:*Allergology International, Volume 64, Issue 4 Author(s): Hiroaki Matsuo, Tomoharu Yokooji, Takanori Taogoshi Food allergy is an adverse immune response to certain kinds of food. Although any food can cause allergic reactions, chicken egg, cow's milk, wheat, shellfish, fruit, and buckwheat account for 75% of food allergies in Japan. Allergen-specific immunoglobulin E (IgE) antibodies play a pivotal role in the development of food allergy. Recent advances in molecular biological techniq...περισσότερα »
Food Allergies
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
: The Basics via ScienceDirect Search: baker’s asthma *Source:*Gastroenterology, Volume 148, Issue 6 Author(s): Rudolf Valenta, Heidrun Hochwallner, Birgit Linhart, Sandra Pahr IgE-associated food allergy affects approximately 3% of the population and has severe effects on the daily life of patients—manifestations occur not only in the gastrointestinal tract but also affect other organ systems. Birth cohort studies have shown that allergic sensitization to food allergens develops early in childhood. Mechanisms of pathogenesis include cross-linking of mast cell– and basophil-bound IgE a... περισσότερα »
Food Allergy and Food-Induced Anaphylaxis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Signs and Symptoms of via ScienceDirect Search: baker’s asthma *Source:*Pediatric Clinics of North America, Volume 62, Issue 6 Author(s): Hemant P. Sharma, Shweta Bansil, Burcin Uygungil TeaserFood allergies are increasing in prevalence. In order for pediatric clinicians to appropriately diagnose and manage food allergies, the characteristic signs and symptoms of these potentially severe reactions must be recognized. Unlike nonimmunologic adverse food reactions (such as lactose intolerance and food poisoning), food allergies by definition are immune-mediated responses that occur rep... περισσότερα »
Component-resolved diagnosis of baker's allergy based on specific IgE to recombinant wheat flour proteins
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Component-resolved diagnosis of baker's allergy based on specific IgE to recombinant wheat flour proteins∗ via ScienceDirect Search: baker’s asthma *Source:*Journal of Allergy and Clinical Immunology, Volume 135, Issue 6 Author(s): Ingrid Sander, Hans-Peter Rihs, Gert Doekes, Santiago Quirce, Esmeralda Krop, Peter Rozynek, Vera van Kampen, Rolf Merget, Ursula Meurer, Thomas Brüning, Monika Raulf BackgroundSensitization to wheat flour plays an important role in the development and diagnosis of baker's asthma.ObjectivesWe evaluated wheat allergen components as sensitizers for bakers with... περισσότερα »
Stimulus train duration but not attention moderates γ-band entrainment abnormalities in schizophrenia.
Alexandros G. SfakianakisστοHead and NeckΠριν από 4 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Stimulus train duration but not attention moderates γ-band entrainment abnormalities in schizophrenia.* Schizophr Res. 2015 Jun;165(1):97-102 Authors: Hamm JP, Bobilev AM, Hayrynen LK, Hudgens-Haney ME, Oliver WT, Parker DA, McDowell JE, Buckley PA, Clementz BA Abstract Electroencephalographic (EEG) studies of auditory steady-state responses (aSSRs) non-invasively probe gamma-band (40-Hz) oscillatory capacity in sensory cortex with high signal-to-noise ratio. Consistent reports of reduced 40-Hz aSSRs in persons w... περισσότερα »
Food processing and allergenicity
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Food processing and allergenicity via ScienceDirect Search: baker’s asthma *Source:*Food and Chemical Toxicology, Volume 80 Author(s): Kitty C.M. Verhoeckx, Yvonne M. Vissers, Joseph L. Baumert, Roland Faludi, Marcel Feys, Simon Flanagan, Corinne Herouet-Guicheney, Thomas Holzhauser, Ryo Shimojo, Nieke van der Bolt, Harry Wichers, Ian Kimber Food processing can have many beneficial effects. However, processing may also alter the allergenic properties of food proteins. A wide variety of processing methods is available and their use depends largely on the food to be processed.In this re... περισσότερα »
Thiazolidine-2,4-dione derivatives: Diabetes, diabetic complications, cancer, arthritis, inflammation, microbial infection, and melanoma, etc.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Thiazolidine-2,4-dione derivatives: Programmed chemical weapons for key protein targets of various pathological conditions via ScienceDirect Search: baker’s asthma *Source:*Bioorganic & Medicinal Chemistry, Volume 23, Issue 13 Author(s): Navriti Chadha, Malkeet Singh Bahia, Maninder Kaur, Om Silakari Thiazolidine-2,4-dione is an extensively explored heterocyclic nucleus for designing of novel agents implicated for a wide variety of pathophysiological conditions, that is, diabetes, diabetic complications, cancer, arthritis, inflammation, microbial infection, and melanoma, etc. The curre... περισσότερα »
The Utility of Ankle-Brachial Index as a Predictor of Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*The Utility of Ankle-Brachial Index as a Predictor of Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage.* World Neurosurg. 2016 Jan 29; Authors: Guan J, Karsy M, Brock A, Couldwell WT PMID: 26828462 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1nKoMVe via IFTTT
Brain Contusions and SUR1 Receptors: Has a New Target Been Born?
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Brain Contusions and SUR1 Receptors: Has a New Target Been Born?* World Neurosurg. 2016 Jan 29; Authors: Welling LC, Welling MS, Teixeira MJ, Figueiredo EG PMID: 26828461 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1nKoJsK via IFTTT
Understanding Neurogenesis in the Subventricular Zone and the Capacity for Transcriptional Modulation in Ischemic Brain Injury.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Understanding Neurogenesis in the Subventricular Zone and the Capacity for Transcriptional Modulation in Ischemic Brain Injury.* World Neurosurg. 2016 Jan 29; Authors: Abecassis IJ, Levitt MR PMID: 26828460 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1VGuZMv via IFTTT
No Early Mobilization After Stroke: Lessons Learned from the AVERT Trial.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*No Early Mobilization After Stroke: Lessons Learned from the AVERT Trial.* World Neurosurg. 2016 Jan 29; Authors: Awad AJ, Kellner CP, Mascitelli JR, Bederson JB, Mocco J PMID: 26828459 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1nKoMou via IFTTT
Hypothermia not Supported as a Therapeutic Option for Traumatic Brain Injury in Recent Randomized Trial.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Hypothermia not Supported as a Therapeutic Option for Traumatic Brain Injury in Recent Randomized Trial.* World Neurosurg. 2016 Jan 29; Authors: Pines AR, Halasa TK, Sittur MG, Aoun RJ, Bendok BR PMID: 26828458 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1VGv0zS via IFTTT
The Fate of Adjacent Segments after Anterior Cervical Discectomy and Fusion: The Influence of an Anterior Plate System.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*The Fate of Adjacent Segments after Anterior Cervical Discectomy and Fusion: The Influence of an Anterior Plate System.* World Neurosurg. 2016 Jan 29; Authors: Ahn SS, Paik HK, Chin DK, Kim SH, Kim DW, Ku MG Abstract OBJECTIVE: The purpose of this study was to compare anterior cervical discectomy and fusion with cage alone (ACDF-CA) and ACDF with cage and plate (ACDF-CP) with regard to ASD diagnosed using CT and MRI with retrospective matched cohort design. METHODS: This study enrolled 68 patients who underwent single-level ACDF who were diagnosed with cervical degenerative disc... περισσότερα »
All Plagiarism Is Not Alike.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*All Plagiarism Is Not Alike.* World Neurosurg. 2016 Jan 29; Authors: Benzel E PMID: 26828456 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1nKoM7T via IFTTT
Carotid Endarterectomy: How surgeons, neurologists and internists can be greater than the sum of their parts.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Carotid Endarterectomy: How surgeons, neurologists and internists can be greater than the sum of their parts.* World Neurosurg. 2016 Jan 28; Authors: Howard BM, Barrow DL PMID: 26827670 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1VGuWQG via IFTTT
Analysis of how people with intellectual disabilities organize information using computerized guidance.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Analysis of how people with intellectual disabilities organize information using computerized guidance.* Disabil Rehabil Assist Technol. 2016 Feb 1;:1-10 Authors: Lussier-Desrochers D, Sauzéon H, Consel C, Roux J, Balland É, Godin-Tremblay V, N'Kaoua B, Lachapelle Y Abstract Access to residential settings for people with intellectual disabilities (ID) contributes to their social participation, but presents particular challenges. Assistive technologies can help people perform activities of daily living. However, the majority of the computerized solutions offered use guidance mod... περισσότερα »
Erratum.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Erratum.* Future Oncol. 2016 Feb 1; Authors: PMID: 26829323 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1Pd1v4Q via IFTTT
Eventual role of EGFR-tyrosine kinase inhibitors in early-stage non-small-cell lung cancer.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Eventual role of EGFR-tyrosine kinase inhibitors in early-stage non-small-cell lung cancer.* Future Oncol. 2016 Feb 1; Authors: Marquez-Medina D, Popat S Abstract Nonadvanced non-small-cell lung cancer (NSCLC) has a poor long-term survival from surgery or definitive radiation that is minimally improved with induction/adjuvant conventional chemotherapy. EGFR-tyrosine kinase inhibitors (EGFR-TKIs), which provide a significant benefit for molecularly selected EGFR-mutant patients with advanced NSCLC, have been infrequently explored in nonadvanced NSCLC to date. Current published s...περισσότερα »
Low-dose radiotherapy and concurrent FOLFIRI-bevacizumab: a Phase II study.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Low-dose radiotherapy and concurrent FOLFIRI-bevacizumab: a Phase II study.* Future Oncol. 2016 Feb 1; Authors: Morganti AG, Cellini F, Mignogna S, Padula GD, Caravatta L, Deodato F, Picardi V, Macchia G, Cilla S, Buwenge M, Lullo LD, Gambacorta MA, Balducci M, Mattiucci GC, Autorino R, Valentini V Abstract AIMS: Low-dose radiation therapy (LDRT) can increase biological efficacy of chemotherapy. This Phase II trial evaluates LDRT plus FOLFIRI-bevacizumab (FOLFIRI-B) in metastatic colorectal cancer. MATERIALS & METHODS: Primary objective: raising the clinical complete response r... περισσότερα »
Concepts in cardio-oncology: definitions, mechanisms, diagnosis and treatment strategies of cancer therapy-induced cardiotoxicity.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Concepts in cardio-oncology: definitions, mechanisms, diagnosis and treatment strategies of cancer therapy-induced cardiotoxicity.* Future Oncol. 2016 Feb 1; Authors: Wickramasinghe CD, Nguyen KL, Watson KE, Vorobiof G, Yang EH Abstract There has been considerable improvement in cancer survival rates, primarily through improved preventive strategies and novel anticancer drugs. Cancer is now becoming a chronic illness and as such both short and long-term cardiotoxic effects of cancer therapy are becoming more apparent. This has led to the emergence of a new multidisciplinary spec...περισσότερα »
Molecularly targeted therapy in acute myeloid leukemia.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Molecularly targeted therapy in acute myeloid leukemia.* Future Oncol. 2016 Feb 1; Authors: Gill H, Leung AY, Kwong YL Abstract Acute myeloid leukemia (AML) is molecularly heterogeneous. Formerly categorized cytogenetically and molecularly, AML may be classified by genomic and epigenomic analyses. These genetic lesions provide therapeutic targets. Genes targeted currently include mutated FLT3, NPM1 and KIT with drugs entering Phase III trials. Complete remission can be achieved in relapsed/refractory AML, albeit mostly transient. Mutated epigenetic modifiers, including DNMT3A, ... περισσότερα »
The Roles of MicroRNA-141 in Human Cancers: From Diagnosis to Treatment.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*The Roles of MicroRNA-141 in Human Cancers: From Diagnosis to Treatment.* Cell Physiol Biochem. 2016 Feb 1;38(2):427-448 Authors: Gao Y, Feng B, Han S, Zhang K, Chen J, Li C, Wang R, Chen L Abstract Cancer remains one of the most threatening causes of human health impairment, and the mechanisms underlying tumorigenesis have not been completely characterized. MicroRNAs (miRNAs) are a group of endogenous, small (18∼25 nucleotides) non-coding RNAs which negatively regulate gene expressions by directly binding to the 3'-untranslated regions (3'-UTRs) of the target messenger RNAs (mR... περισσότερα »
Radiogenomics - current status, challenges and future directions.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Radiogenomics - current status, challenges and future directions.* Cancer Lett. 2016 Jan 28; Authors: Andreassen CN, Schack LM, Laursen LV, Alsner J Abstract Radiogenomics designates a scientific field that addresses possible associations between genetic germline alterations and normal tissue toxicity after radiotherapy. The ultimate aim of this research is to establish a gene-based predictive test for normal tissue radiosensitivity. During the last 5 years, substantial progress has been achieved in this field. Several compelling associations for SNPs have been demonstrated in ...περισσότερα »
Gene-expression signatures in ovarian cancer: Promise and challenges for patient stratification.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Gene-expression signatures in ovarian cancer: Promise and challenges for patient stratification.* Gynecol Oncol. 2016 Jan 28; Authors: Konecny GE, Winterhoff B, Wang C Abstract Microarray-based gene expression studies demonstrate that ovarian cancer is both a clinically diverse and molecularly heterogeneous disease compromising subtypes with distinct gene expression patterns that are each associated with statistically significant different clinical outcomes. The information provided by gene expression based assays is promising and deserves incorporation into clinical decision-m... περισσότερα »
Innovative perspectives of immunotherapy in head and neck cancer. From relevant scientific rationale to effective clinical practice.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Innovative perspectives of immunotherapy in head and neck cancer. From relevant scientific rationale to effective clinical practice.* Cancer Treat Rev. 2016 Feb;43:113-23 Authors: Lalami Y, Awada A Abstract It is now well established that head and neck cancer carcinogenesis is characterized by genetic instability and several immune defects, leading to unique host-tumor interactions. In such condition, recent improved comprehension and relevant findings could lead to identification of innovative molecular therapeutic targets, achieving considerable clinical and translational res... περισσότερα »
Why have ovarian cancer mortality rates declined? Part III. Prospects for the future.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Why have ovarian cancer mortality rates declined? Part III. Prospects for the future.* Gynecol Oncol. 2015 Sep;138(3):757-61 Authors: Sopik V, Rosen B, Giannakeas V, Narod SA Abstract Over the last 40 years, the age-adjusted ovarian cancer mortality rate in the USA declined by 23%. The decline in mortality paralleled a decline in incidence, which was largely due to changes in reproductive risk factors. There was no reduction in ovarian cancer case-fatality at 12 years, indicating that improvements in early detect... περισσότερα »
Impact of comorbidities on the treatment of non-Hodgkin's lymphoma: a systematic review.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
Related Articles *Impact of comorbidities on the treatment of non-Hodgkin's lymphoma: a systematic review.* Expert Rev Hematol. 2015 Jun;8(3):329-41 Authors: Terret C, Albrand G, Rainfray M, Soubeyran P Abstract Treating non-Hodgkin's lymphoma in patients with comorbidities can be challenging because of possible interactions that may alter the treatment efficacy. We conducted a systematic review to determine the impact of comorbidities on various outcomes, evaluate the current data, and provide recommendations for future research. Twenty-one articles were selected. However, the ...περισσότερα »
Update of hematopoietic cell transplantation for sickle cell disease.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Update of hematopoietic cell transplantation for sickle cell disease.* Curr Opin Hematol. 2015 May;22(3):227-33 Authors: Walters MC Abstract PURPOSE OF REVIEW: Hematopoietic cell transplantation (HCT) is a curative therapy for sickle cell disease (SCD) that is utilized very rarely because of limited allogeneic donor availability, limited healthcare resources needed to expand the treatment to regions in the world where most affected individuals reside, and by a view among SCD experts that HCT lacks the evidential ...περισσότερα »
Analyzing large-scale samples confirms the association between rs16892766 polymorphism and colorectal cancer susceptibility.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
[image: http:--http://ift.tt/1feGv2I] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Analyzing large-scale samples confirms the association between rs16892766 polymorphism and colorectal cancer susceptibility.* Sci Rep. 2015;5:7957 Authors: Liao M, Wang G, Quan B, Qi X, Yu Z, Feng R, Zhang L, Jiang Y, Zhang Y, Liu G Abstract Colorectal cancer (CRC) is a common complex disease caused by the combination of genetic variants and environmental factors. Genome-wide association studies (GWAS) have been performed and reported some novel CRC susceptibility variants. The rs168927...περισσότερα »
Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing.* Hum Mol Genet. 2015 Apr 15;24(8):2318-29 Authors: Kunstman JW, Juhlin CC, Goh G, Brown TC, Stenman A, Healy JM, Rubinstein JC, Choi M, Kiss N, Nelson-Williams C, Mane S, Rimm DL, Prasad ML, Höög A, Zedenius J, Larsson C, Korah R, Lifton RP, Carling T Abstract Anaplastic thyroid carcinoma (ATC) is a frequently lethal malignancy that is often unresponsive to available therapeutic strategies. The tumorigenesis of A...περισσότερα »
Development and validation of a prognostic model for recurrent glioblastoma patients treated with bevacizumab and irinotecan.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Development and validation of a prognostic model for recurrent glioblastoma patients treated with bevacizumab and irinotecan.* Acta Oncol. 2016 Feb 1;:1-5 Authors: Urup T, Dahlrot RH, Grunnet K, Christensen IJ, Michaelsen SR, Toft A, Larsen VA, Broholm H, Kosteljanetz M, Hansen S, Poulsen HS, Lassen U Abstract Background Predictive markers and prognostic models are required in order to individualize treatment of recurrent glioblastoma (GBM) patients. Here, we sought to identify clinical factors able to predict response and survival in recurrent GBM patients treated with bevacizu...περισσότερα »
Centralization of Penile Cancer Management in the US: a Combined Analysis of the American Board of Urology and National Cancer Data Base.
Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Centralization of Penile Cancer Management in the US: a Combined Analysis of the American Board of Urology and National Cancer Data Base.* Urology. 2016 Jan 28; Authors: Matulewicz RS, Flum AS, Helenowski I, Jovanovic B, Palis B, Bilimoria KY, Meeks JJ Abstract OBJECTIVE: To assess the potential benefit of centralization of care in penile cancer. Centralization of care in other disease processes standardizes treatment and improves outcomes. Since penile cancer is a rare malignancy with unchanged mortality rates over the last two decades, we hypothesize that there may be a benef...περισσότερα »
Recombinant γ-gliadin 1 for identifying patients with celiac disease and monitoring adherence to a gluten-free diet
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Usefulness of via ScienceDirect Search: baker’s asthma *Source:*Journal of Allergy and Clinical Immunology, Volume 136, Issue 6 Author(s): Bharani Srinivasan, Margarete Focke-Tejkl, Milena Weber, Sandra Pahr, Alexandra Baar, Raja Atreya, Markus F. Neurath, Harald Vogelsang, Wolf-Dietrich Huber, Rudolf Valenta BackgroundCeliac disease (CD) is an inflammatory disease of the small intestine caused by an immunologic hypersensitivity reaction to dietary wheat gluten.ObjectivesWe sought to clone, express, and perform IgA epitope mapping of a CD-specific wheat antigen and to study its useful... περισσότερα »
Gluten and wheat sensitivities
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
– An overview via ScienceDirect Search: baker’s asthma *Source:*Journal of Cereal Science Author(s): Katharina Anne Scherf, Peter Koehler, Herbert Wieser Wheat products are important staple foods worldwide. However, a small portion of the population has to avoid wheat-containing foods because of harmful immune responses. Countless studies have demonstrated that the storage (gluten) proteins of wheat are major causative agents for wheat-dependent immune-mediated disorders. The unique structural features of gluten proteins are long repetitive amino acid sequences rich in glutamine and ...περισσότερα »
Food-induced immunoglobulin E-mediated allergic rhinitis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
Food-induced immunoglobulin E-mediated allergic rhinitis via ScienceDirect Search: baker’s asthma *Source:*Journal of Microscopy and Ultrastructure Author(s): Mohammed W. Al-Rabia BackgroundFood allergies are estimated about 1–2% in adults and 8% in children younger than 6 years. Allergic rhinitis is a common disease with a prevalence of 40% among different societies. Although some foods play a role on exacerbation of allergic-rhinitis symptoms, there are controversies about the role of diet on the incidence or worsening of the symptoms.MethodsA total of 100 patients (including both ch...περισσότερα »
Occupational Hypersensitivity Pneumonitis in a Baker
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
Occupational Hypersensitivity Pneumonitis in a Baker via ScienceDirect Search: baker’s asthma *Source:*Chest, Volume 145, Issue 4 Author(s): Mathieu Gerfaud-Valentin, Gabriel Reboux, Julie Traclet, Françoise Thivolet-Béjui, Jean-François Cordier, Vincent Cottin Bakers are exposed daily to flour and may be susceptible to immunologic occupational diseases. A 30-year-old, nonsmoking, female baker was referred for progressive dyspnea on exertion, basal crackles on auscultation, restrictive lung function, decreased diffusing capacity of the lung for carbon monoxide, ground glass hyperdensit...περισσότερα »
Allergenic Fungi
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
Taxonomy of via ScienceDirect Search: baker’s asthma *Source:*The Journal of Allergy and Clinical Immunology: In Practice Author(s): Estelle Levetin, W. Elliott Horner, James A. Scott The Kingdom Fungi contains diverse eukaryotic organisms including yeasts, molds, mushrooms, bracket fungi, plant rusts, smuts, and puffballs. Fungi have a complex metabolism that differs from animals and plants. They secrete enzymes into their surroundings and absorb the breakdown products of enzyme action. Some of these enzymes are well-known allergens. The phylogenetic relationships among fungi were un... περισσότερα »
Detection and control of soybeans as a food allergen
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
18 via ScienceDirect Search: baker’s asthma Publication date: 2015 *Source:*Handbook of Food Allergen Detection and Control Author(s): S.L. Taylor, B.C. Remington, R. Panda, R.E. Goodman, J.L. Baumert Soybeans and ingredients derived from soybeans are widely used in foods for a variety of technological and nutritional purposes. Soybeans are also considered as a commonly allergenic food on a worldwide basis. However, recent evidence suggests that the prevalence of soybean allergy in the overall population may actually be rather low and suggests that soybeans might be removed from lists... περισσότερα »
Anaphylaxis to wheat after gluten-free diet in an adolescent with celiac disease
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Fatal anaphylaxis to wheat after gluten-free diet in an adolescent with celiac disease via ScienceDirect Search: baker’s asthma *Source:*Allergology International, Volume 64, Issue 2 Dear Editor Food allergy is the primary cause of childhood anaphylaxis. It has been hypothesized that restriction diets in food allergic children may induce an increase of food-specific IgE (sIgE) levels and the risk of anaphylaxis.1 Accordingly, we report the case of a 16-year-old boy who experienced a fatal anaphylaxis to wheat proteins after an exclusion diet due to celiac disease. The patient was born ... περισσότερα »
Non-celiac wheat sensitivity
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
: Differential diagnosis, triggers and implications via ScienceDirect Search: baker’s asthma *Source:*Best Practice & Research Clinical Gastroenterology, Volume 29, Issue 3 Author(s): Detlef Schuppan, Geethanjali Pickert, Muhammad Ashfaq-Khan, Victor Zevallos Non allergy-non-celiac wheat sensitivity (NCWS) has become a common and often overrated diagnosis. Skepticism mainly relates to patients with prominent intestinal symptoms in the absence of general or intestinal signs of inflammation. There is consensus that the major wheat sensitivities, celiac disease and wheat allergy, have to...περισσότερα »
The Chemistry of the Akuammiline Alkaloids.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
*The Chemistry of the Akuammiline Alkaloids.* Alkaloids Chem Biol. 2016;76:171-257 Authors: Adams GL, Smith AB Abstract An update on the literature covering the akuammiline family of alkaloids is presented. This chapter begins with a summary of new akuammiline alkaloids reported since 2000 and is followed by an overview of new reported bioactivities of akuammiline alkaloids since 2000. The remainder of the chapter comprises a comprehensive review of the synthetic chemistry that has been reported in the last 50years concerning akuammiline alkaloids and their structural motifs. P...περισσότερα »
Primary versus secondary achalasia: A diagnostic conundrum.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Related Articles *Primary versus secondary achalasia: A diagnostic conundrum.* Trop Gastroenterol. 2015 Apr-Jun;36(2):86-95 Authors: Gupta P, Debi U, Sinha SK, Thapa BR, Prasad K Abstract A coherent distinction between primary and secondary achalasia is considerably important to clinicians. This is because the therapeutic interventions for the two are entirely different. Whilst pneumatic dilation is the standard treatment in primary achalasia, the same treatment, if instituted in malignant stenosis carries potential risk to the patient and delays appropriate therapy of the underl...περισσότερα »
[TRANSIENT PSEUDOBULBAR SYNDROME IN UNILATERAL FRONTAL OPERCULAR INFARCTS].
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Related Articles *[TRANSIENT PSEUDOBULBAR SYNDROME IN UNILATERAL FRONTAL OPERCULAR INFARCTS].* Ideggyogy Sz. 2015 Sep 30;68(9-10):339-45 Authors: Rózsa A, Torák Gyongyi, Nagy É, Kovács K, Gács G Abstract The classic anterior (frontal) opercular syndrome (Foix-Chavany-Marie sy.) is a cortical pseudobulbar palsy mainly due to bilateral lesions of anterior brain operculum. In 2000 the authors had a 70-year old female patient with acute onset of swallowing and speaking difficulty. Neurological examination established a left facial central palsy, the palsy of the tongue and the soft ... περισσότερα »
[Case Report; A case of tetanus with dysphagia as an initial symptom].
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Related Articles *[Case Report; A case of tetanus with dysphagia as an initial symptom].* Nihon Naika Gakkai Zasshi. 2015 Jul 10;104(7):1464-8 Authors: Okada T, Yabe H, Ando R, Iwaki H, Nishikawa N, Nagai M, Sei H, Nishida N, Nomoto M PMID: 26513966 [PubMed - indexed for MEDLINE] from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1UFZS3l via IFTTT
Esophageal Food Impaction and Eosinophilic Esophagitis: A Retrospective Study, Systematic Review, and Meta-Analysis.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *Esophageal Food Impaction and Eosinophilic Esophagitis: A Retrospective Study, Systematic Review, and Meta-Analysis.* Dig Dis Sci. 2015 Nov;60(11):3181-93 Authors: Hiremath GS, Hameed F, Pacheco A, Olive A, Davis CM, Shulman RJ Abstract BACKGROUND: Esophageal food impaction (EFI) can be the initial presentation of eosinophilic esophagitis (EoE). EoE is characterized by persistent esophageal eosinophilia (EE). Both EFI and EE are related to a variety of conditions. To date, the relationship between EFI, EE, and EoE... περισσότερα »
Clinical, endoscopic and manometric features of the primary motor disorders of the esophagus.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
[image: http:--http://ift.tt/1Q7SQUV] Related Articles *Clinical, endoscopic and manometric features of the primary motor disorders of the esophagus.* Arq Bras Cir Dig. 2015;28(1):32-5 Authors: Martinez JC, Lima GR, Silva DH, Duarte AF, Novo NF, da Silva EC, Pinto PC, Maia AM Abstract BACKGROUND: Significant incidence, diagnostic difficulties, clinical relevance and therapeutic efficacy associated with the small number of publications on the primary esophageal motor disorders, motivated the present study. AIM: To determine the manometric prevalence of these disorders and correla...περισσότερα »
Esophageal mucosal resection versus esophagectomy: a comparative study of surgical results in patients with advanced megaesophagus.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
[image: http:--http://ift.tt/1Q7SQUV] Related Articles *Esophageal mucosal resection versus esophagectomy: a comparative study of surgical results in patients with advanced megaesophagus.* Arq Bras Cir Dig. 2015;28(1):28-31 Authors: de Oliveira GC, da Rocha RL, Coelho-Neto Jde S, Terciotti-Junior V, Lopes LR, Andreollo NA Abstract BACKGROUND: The surgical treatment of advanced megaesophagus has no consensus, being esophagectomy the more commonly used method. Since it has high morbimortality--inconvenient for benign disease -, in recent years an alternative has been introduced: th...περισσότερα »
Minimal endoscopic changes in non-erosive reflux disease.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
[image: http:--http://ift.tt/1Q7SQUV] Related Articles *Minimal endoscopic changes in non-erosive reflux disease.* Arq Bras Cir Dig. 2015;28(1):20-3 Authors: Ratin AC, Orso IR Abstract BACKGROUND: Gastroesophageal reflux disease is an increasingly common condition worldwide causing a considerable economic impact. More than half the patients with clinical symptoms of reflux disease display no mucosal erosions on esophagogastroduodenoscopy, making it impossible to confirm the diagnosis without further investigations. AIM: To evaluate the correlation between minimal endoscopic change...περισσότερα »
Clinical, metabolic, and psychological characteristics in patients with gastroesophageal reflux disease overlap with irritable bowel syndrome.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Clinical, metabolic, and psychological characteristics in patients with gastroesophageal reflux disease overlap with irritable bowel syndrome.* Eur J Gastroenterol Hepatol. 2015 May;27(5):516-22 Authors: Hsu CS, Liu TT, Wen SH, Wang CC, Yi CH, Chen JH, Lei WY, Orr WC, Fabio P, Chen CL Abstract OBJECTIVES: Gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS) are highly prevalent in the general population, with significant symptom overlap, whereas the interaction between both remains poorly und...περισσότερα »
Toxic cerebellar syndrome due to methotrexate.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Toxic cerebellar syndrome due to methotrexate.* Pract Neurol. 2015 Jun;15(3):214-5 Authors: Kinzel O, Verma RK, Wiest R, Mattle HP PMID: 25814514 [PubMed - indexed for MEDLINE] from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1Sq1SPT via IFTTT
Rehabilitation Nutrition for Possible Sarcopenic Dysphagia After Lung Cancer Surgery: A Case Report.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
*Rehabilitation Nutrition for Possible Sarcopenic Dysphagia After Lung Cancer Surgery: A Case Report.* Am J Phys Med Rehabil. 2016 Jan 29; Authors: Wakabayashi H, Uwano R Abstract Sarcopenic dysphagia is characterized by the loss of swallowing muscle mass and function associated with generalized loss of skeletal muscle mass and function. In this report, the authors describe a patient with possible sarcopenic dysphagia after lung cancer surgery and was treated subsequently by rehabilitation nutrition. A 71-year-old man with lung cancer experienced complications of an acute myocar... περισσότερα »
Natural history and management of refractory benign esophageal strictures.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
*Natural history and management of refractory benign esophageal strictures.* Gastrointest Endosc. 2016 Jan 29; Authors: Repici A, Small AJ, Mendelson A, Jovani M, Correlae L, Hassan C, Ridola L, Anderloni A, Ferrara EC, Kochman ML Abstract BACKGROUND AND AIMS: Natural history of refractory benign esophageal strictures (RBES) is unclear, and surgery or PEG may be the only viable long-term option. The aim of the present study was to assess the long-term outcomes of patients with RBES. METHODS: Clinical data of consecutive RBES-patients treated in the last 15 years in 2 tertiary ref... περισσότερα »
IgE-mediated food allergies
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Food Allergies via ScienceDirect Search: baker’s asthma Publication date: 2016 *Source:*Encyclopedia of Food and Health Author(s): S.L. Taylor, J.L. Baumert Food allergies are individualistic adverse reactions, mediated by abnormal responses of the immune system to specific proteins contained in certain foods. Food allergies affect only a small percentage of the population. The symptoms of IgE-mediated food allergies range from mild to severe and life-threatening. Peanuts, tree nuts, crustacean shellfish, fish, milk, eggs, soybeans, and wheat are the most common causes of IgE-mediated ... περισσότερα »
Shear, heat and pH induced conformational changes of wheat gluten – Impact on antigenicity
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Shear, heat and pH induced conformational changes of wheat gluten – Impact on antigenicity via ScienceDirect Search: baker’s asthma Publication date: 1 April 2016 *Source:*Food Chemistry, Volume 196 Author(s): Toheder Rahaman, Todor Vasiljevic, Lata Ramchandran Processing can induce conformational changes of food proteins depending on the conditions used that may affect their antigenicity. This study investigated the effect of pH (3,5,7) temperature (80,90,100°C) and shear (500,1000,1500s−1) on the conformational changes (surface hydrophobicity, FTIR, SDS–PAGE and thiol content) of glu...περισσότερα »
Adverse Reactions to Food
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
4 Adverse Reactions to Food via ScienceDirect Search: baker’s asthma Publication date: 2016 *Source:*Allergy, Immunity and Tolerance in Early Childhood Author(s): Birgit Ahrens, Hugh A. Sampson, Kirsten Beyer Food allergies appear to have increased worldwide. Most food allergic reactions in early childhood are caused by hen's eggs, cow's milk, peanuts, tree nuts, wheat, soy, fish, and sesame. Symptoms are heterogeneous and can involve every organ system. In hen's eggs, cow's milk, wheat, and soy allergy, natural tolerance develops frequently, whereas peanut and tree nut allergy is oft...περισσότερα »
Food Allergies: baker’s asthma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Shear, heat and pH induced conformational changes of wheat gluten – Impact on antigenicity Publication date: 1 April 2016 *Source:*Food Chemistry, Volume 196 Author(s): Toheder Rahaman, Todor Vasiljevic, Lata Ramchandran Processing can induce conformational changes of food proteins depending on the conditions used that may affect their antigenicity. This study investigated the effect of pH (3,5,7) temperature (80,90,100°C) and shear (500,1000,1500s−1) on the conformational changes (surface hydrophobicity, FTIR, SDS–PAGE and thiol content) of gluten in relation to its antigenicity (d...περισσότερα »
[Nonalcoholic steatohepatitis after pancreatoduodenectomy with rapid progression of hepatic fibrosis: a case report].
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
[image: http:--linkout.jstage.jst.go.jp-logo_non] Related Articles *[Nonalcoholic steatohepatitis after pancreatoduodenectomy with rapid progression of hepatic fibrosis: a case report].* Nihon Shokakibyo Gakkai Zasshi. 2015 May;112(5):905-13 Authors: Asama H, Suzuki T, Kita E, Matsuhashi N, Ichii O, Tai M, Ejiri Y, Ohira H Abstract A 64-year-old woman who had undergone pancreatoduodenectomy for intraductal papillary mucinous carcinoma 10 months previously was referred to our department complaining of ascites and general malaise. Abdominal computed tomography (CT) showed a markedl...περισσότερα »
Dietary cadmium intake and risk of prostate cancer: a Danish prospective cohort study.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Dietary cadmium intake and risk of prostate cancer: a Danish prospective cohort study.* BMC Cancer. 2015;15:177 Authors: Eriksen KT, Halkjær J, Meliker JR, McElroy JA, Sørensen M, Tjønneland A, Raaschou-Nielsen O Abstract BACKGROUND: Cadmium is classified as a human lung carcinogen based on evidence from high-exposure occupational settings. Though cadmium has no physiological role, increasing evidence suggests cadmium may mimic steroid hormones. This dual ability of being carcinogenic a...περισσότερα »
The effect of ginger (Zingiber officinale) on glycemic markers in patients with type 2 diabetes.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Related Articles *The effect of ginger (Zingiber officinale) on glycemic markers in patients with type 2 diabetes.* J Complement Integr Med. 2015 Jun;12(2):165-70 Authors: Shidfar F, Rajab A, Rahideh T, Khandouzi N, Hosseini S, Shidfar S Abstract BACKGROUND: Ginger (Zingiber officinale) is one of the functional foods which contains biological compounds including gingerol, shogaol, paradol and zingerone. Ginger has been proposed to have anti-cancer, anti-thrombotic, anti-inflammatory, anti-arthritic, hypolipidemic and analgesic properties. Here, we report the effect of ginger supp... περισσότερα »
Invasomes of isradipine for enhanced transdermal delivery against hypertension: formulation, characterization, and in vivo pharmacodynamic study.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Invasomes of isradipine for enhanced transdermal delivery against hypertension: formulation, characterization, and in vivo pharmacodynamic study.* Artif Cells Nanomed Biotechnol. 2016 Feb 1;:1-7 Authors: Qadri GR, Ahad A, Aqil M, Imam SS, Ali A Abstract Context Isradipine is an effective calcium channel blocker used in the management of hypertension. It undergoes extensive first pass metabolism and has low oral bioavailability. Hence we attempted to develop isradipine-loaded invasomes. Objective The purpose of this work was to prepare and characterize invasomes carrier for isra... περισσότερα »
Value of serial preablative thyroglobulin measurements: can we address the impact of thyroid remnants?
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Value of serial preablative thyroglobulin measurements: can we address the impact of thyroid remnants?* Nucl Med Commun. 2016 Jan 29; Authors: Zhao T, Liang J, Li T, Guo Z, Vinjamuri S, Lin Y Abstract OBJECTIVE: Preablative stimulated thyroglobulin (ps-Tg) is somewhat nonspecific when used as a predictive marker for distant metastases (DM) from differentiated thyroid carcinoma because of the impact of residual tissue postsurgery. The aim of this study was to explore the potential value of serial ps-Tg measurements and assess the clinical value of these measurements in the conte... περισσότερα »
Specific metabolic profiles and their relationship to insulin resistance in recent-onset type-1 and type-2 diabetes.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Specific metabolic profiles and their relationship to insulin resistance in recent-onset type-1 and type-2 diabetes.* J Clin Endocrinol Metab. 2016 Feb 1;:jc20154133 Authors: Knebel B, Strassburger K, Szendroedi J, Kotzka J, Scheer M, Nowotny B, Müssig K, Lehr S, Pacini G, Finner H, Klüppelholz B, Giani G, Al-Hasani H, Roden M, GDS Group Abstract CONTEXT: Insulin resistance reflects inadequate insulin-mediated utilization of metabolites and predicts type 2 diabetes (T2D) but is also frequently seen in long standing type 1 diabetes (T1D) and represents a major cardiovascular ris...περισσότερα »
Vitamin D 20,000 IU per Week for Five Years does not Prevent Progression from Prediabetes to Diabetes.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Vitamin D 20,000 IU per Week for Five Years does not Prevent Progression from Prediabetes to Diabetes.* J Clin Endocrinol Metab. 2016 Feb 1;:jc20154013 Authors: Jorde R, Sollid ST, Svartberg J, Schirmer H, Joakimsen RM, Njølstad I, Fuskevåg OM, Figenschau Y, Hutchinson MY Abstract CONTEXT: Vitamin D deficiency is associated with insulin resistance and risk of future diabetes. OBJECTIVE: To test if supplementation with vitamin D to subjects with prediabetes will prevent progression to type 2 diabetes (T2DM). DESIGN: Randomized controlled trial performed 2008 - 2015. SETTING: Clini... περισσότερα »
Beta-cell mass in non-diabetic autoantibody-positive subjects: an analysis based on the nPOD database.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Beta-cell mass in non-diabetic autoantibody-positive subjects: an analysis based on the nPOD database.* J Clin Endocrinol Metab. 2016 Feb 1;:jc20153756 Authors: Diedisheim M, Mallone R, Boitard C, Larger E Abstract CONTEXT: Little information is available about beta-cell mass in antibody-positive (Ab+) non-diabetic subjects. OBJECTIVE: We have investigated whether the publicly available virtual slides of the nPOD project can be used to assess beta-cell mass and distribution in non-diabetic Ab- and Ab+ subjects and in patients with recent onset type 1 diabetes (T1D). SUBJECTS AND... περισσότερα »
Impaired Insulin Suppression of VLDL-Triglyceride Kinetics in Non-alcoholic Fatty Liver Disease.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Impaired Insulin Suppression of VLDL-Triglyceride Kinetics in Non-alcoholic Fatty Liver Disease.* J Clin Endocrinol Metab. 2016 Feb 1;:jc20153476 Authors: Poulsen MK, Nellemann B, Stødkilde-Jørgensen H, Pedersen SB, Grønbæk H, Nielsen S Abstract CONTEXT: Non-alcoholic fatty liver disease (NAFLD) is associated with glucose and lipid metabolic abnormalities. However, insulin suppression of VLDL-triglyceride (VLDL-TG) kinetics is not fully understood. OBJECTIVE: To determine VLDL-TG, glucose and palmitate kinetics during fasting and hyperinsulinemia in men with (NAFLD+) and without...περισσότερα »
Obesity-associated inflammation induces microRNA-155 expression in adipocytes and adipose tissue: outcome on adipocyte function.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Obesity-associated inflammation induces microRNA-155 expression in adipocytes and adipose tissue: outcome on adipocyte function.* J Clin Endocrinol Metab. 2016 Feb 1;:jc20153410 Authors: Karkeni E, Astier J, Tourniaire F, El Abed M, Romier B, Gouranton E, Lin W, Borel P, Salles J, Walrand S, Ye J, Landrier JF Abstract CONTEXT: Obesity alters adipose tissue metabolic and endocrine functions and causes a chronic local and systemic low-grade inflammatory state to develop, generating obesity-associated complications. In the last decade, many entities contributing to and regulating t...περισσότερα »
Angiogenesis inhibitor; +20 new citations
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
20 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Angiogenesis inhibitor* These pubmed results were generated on 2016/02/02 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1Pwkpav via IFTTT
Human olfactory stem cells for injured facial nerve reconstruction in a rat model.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Human olfactory stem cells for injured facial nerve reconstruction in a rat model.* Head Neck. 2016 Feb 1; Authors: Batioglu-Karaaltin A, Karaaltin MV, Oztel ON, Ovali E, Sener BM, Adatepe T, Yigit O, Bozkurt E, Baydar SY, Bagirova M, Uzun N, Allahverdiyev A Abstract BACKGROUND: The purpose of this study was to show the efficacy of olfactory stem cells for injured facial nerve reconstruction in a rat model. METHODS: Olfactory stem cells were isolated from the olfactory mucosa of human participants. A 2-mm excision was performed on the right facial nerve of all rats. Reconstruct...περισσότερα »
Intermittent intraoperative nerve monitoring in thyroid reoperations: Preliminary results of a randomized, single-surgeon study.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Intermittent intraoperative nerve monitoring in thyroid reoperations: Preliminary results of a randomized, single-surgeon study.* Head Neck. 2016 Feb 1; Authors: Hei H, Zhou B, Qin J, Song Y Abstract BACKGROUND: The purpose of this study was to evaluate whether intermittent intraoperative nerve monitoring (IONM) could reduce the incidence of recurrent laryngeal nerve (RLN) paralysis in thyroid reoperations. METHODS: Enrolled patients were randomly assigned into the nerve integrity monitor (NIM) group and the control group. RESULTS: The incidence of temporary RLN paralysis and per... περισσότερα »
A case of lipoma arising in the eustachian tube.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*A case of lipoma arising in the eustachian tube.* Ear Nose Throat J. 2016 Jan;95(1):E5-E7 Authors: Dabiri J, Choufani G, Delpierre I, Hassid S Abstract We report a case of a lipoma inside the eustachian tube, an extremely rare location for this lesion. To the best of our knowledge, this is only the second such case that has been described in the literature. The patient was a 47-year-old man, a fighter pilot, who was referred to our hospital with a 3-year history of (1) fullness in the right ear secondary to recurrent serous otitis media and (2) right ear pain, which was especial... περισσότερα »
Congenital choristoma (hairy polyp) of the eustachian tube: Surgical management of a rare clinical entity.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Congenital choristoma (hairy polyp) of the eustachian tube: Surgical management of a rare clinical entity.* Ear Nose Throat J. 2016 Jan;95(1):E43-E45 Authors: Melzer JM, Morgan A, Darrow D PMID: 26829696 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1o1LTe1 via IFTTT
Slag injury to the tympanic membrane.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Slag injury to the tympanic membrane.* Ear Nose Throat J. 2016 Jan;95(1):E39-E40 Authors: Marchiano E, Jyung RW PMID: 26829694 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1o1LV5y via IFTTT
A useful technique for adjusting nasal tip projection in Asian rhinoplasty: Trapezoidal caudal extension cartilage grafting.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*A useful technique for adjusting nasal tip projection in Asian rhinoplasty: Trapezoidal caudal extension cartilage grafting.* Ear Nose Throat J. 2016 Jan;95(1):E17-E22 Authors: Liu SC, Lin DS, Wang HW, Kao CH Abstract The purpose of this article is to present our experience with Asian patients in (1) using a trapezoidal caudal extension cartilage graft to adjust the tip projection in tip refinement for augmentation rhinoplasty, especially for the correction of short nose, and (2) avoiding complications of augmentation rhinoplasty with alloplastic implants. We conducted a retros... περισσότερα »
Urbach-Wiethe disease in a young woman: A case report.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Urbach-Wiethe disease in a young woman: A case report.* Ear Nose Throat J. 2016 Jan;95(1):E14-E16 Authors: Jansen S, Quante G, Luers JC, Beutner D Abstract Urbach-Wiethe disease (lipoid proteinosis) is an autosomal recessive disorder that is characterized by a general thickening of the skin and mucous membranes. We report the case of a 22-year-old woman with lipoid proteinosis who presented with hoarseness, poor dentition, and skin lesions, and we discuss the management of this rare disease. PMID: 26829688 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inor... περισσότερα »
Retained crossbow bolt after penetrating facial trauma.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Retained crossbow bolt after penetrating facial trauma.* Ear Nose Throat J. 2016 Jan;95(1):E1-E4 Authors: Shah MU, Sridhara SK, Wolf JS, Ambro BT Abstract We present an unusual case of a retained crossbow bolt in the maxillofacial area of a 31-year-old man. While crossbow injuries are rare, this case is of interest because otolaryngologists are often faced with treating retained foreign objects after penetrating facial trauma. These cases are difficult to manage because of the complexity and variety of injuries that can occur during both the initial trauma and the removal. We fo... περισσότερα »
Granular cell (Abrikossoff) tumor in the head and neck: A series of 5 cases.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Granular cell (Abrikossoff) tumor in the head and neck: A series of 5 cases.* Ear Nose Throat J. 2016 Jan;95(1):36-39 Authors: Koltsidopoulos P, Chaidas K, Chlopsidis P, Skoulakis C Abstract We evaluated a series of 5 patients-3 men and 2 women, aged 39 to 70 years (mean: 54.4)-with a granular cell tumor (GCT) of the head and neck in an effort to better define the clinical presentation, imaging characteristics, and surgical management of this type of tumor. In all cases, the diagnosis was established by pathologic analysis. There were 2 cases of laryngeal GCT and 1 case each of... περισσότερα »
Laryngotracheal mucormycosis: Report of a case.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Laryngotracheal mucormycosis: Report of a case.* Ear Nose Throat J. 2016 Jan;95(1):29-39 Authors: Mattioni J, Portnoy JE, Moore JE, Carlson D, Sataloff RT Abstract Airway mucormycosis is a deadly opportunistic infection that affects immunocompromised persons, particularly diabetics and those undergoing chemotherapy. Although it is typically a pulmonary or sinonasal infection, mucormycosis can affect the larynx and trachea, with devastating results. We report the case of a 46-year-old man with human immunodeficiency virus infection, hepatitis C infection, neurosyphilis, and recen...περισσότερα »
Impaired barrier function in patients with house dust mite–induced allergic rhinitis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Impaired barrier function in patients with house dust mite–induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression via Allergy and Clinical Immunology Publication date: Available online 2 February 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Brecht Steelant, Ricard Farré, Paulina Wawrzyniak, Jochen Belmans, Emily Dekimpe, Hanne Vanheel, Laura Van Gerven, Inge Kortekaas Krohn, Dominique M.A. Bullens, Jan L. Ceuppens, Cezmi A. Akdis, Guy Boeckxstaens, Sven F. Seys, Peter W. Hellings BackgroundTight junction (TJ) defects have... περισσότερα »
An accelerated dose escalation with a grass pollen allergoid is safe and well-tolerated: a randomized open label phase II trial
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
An accelerated dose escalation with a grass pollen allergoid is safe and well-tolerated: a randomized open label phase II trial: Background: The number of injections in the dose escalation of subcutaneous immunotherapy (SCIT) is small for some currently used hypoallergenic allergoids, but can still be inconvenient to patients and can impair compliance. The aim of this trial was to compare safety and tolerability of an accelerated to the conventional dose escalation scheme of a grass pollen allergoid. Methods: In an open label phase II trial, 122 patients were 1:1 randomized for SCIT ... περισσότερα »
Streptococcus agalactiae (GBS) evade immune reactions by interacting with the host immune cells via the sialic acid of sialylated capsular polysaccharides
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Discovery and expression of 3 siglecs-like in Oreochromis niloticus neutrophil, and their interaction with group B streptococcal sialylated capsular polysaccharides via ScienceDirect Publication: Molecular Immunology Publication date: Available online 1 February 2016 *Source:*Molecular Immunology Author(s): Junjian Dong, Yuanzheng Wei, Xing Ye, Chengfei Sun, Yuanyuan Tian, Maixin Lu, Juanjuan Du, Zhihang Chen Sialic acid – binding immunoglobulin – like lectins (Siglecs) are members of the largest superfamily of immune receptors; they recognize sialic acid and are mainly expressed in im... περισσότερα »
Psychological distress in patients with a facial paralysis using the Hospital Anxiety and Depression Scale
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Psychological distress in patients with a facial paralysis using the Hospital Anxiety and Depression Scale: Anxiety and depression are seen among patients with facial paralysis (FP), but less is known about the exact prevalence. The aim of the current study is to assess the presence of anxiety and depressive disorders in the FP population and to investigate possible differences between patients with a left and right FP.
The prevalence of skin tears in the acute care setting
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
The prevalence of skin tears in the acute care setting in Singapore: Skin tears appear to be a hidden and extensive problem despite an increased focus in the literature on skin tear epidemiology, prevention strategies and management modalities. Currently, there has been no report of skin tear epidemiology published in Singapore. The aim of the present study was to pilot the methodology by WoundWest at one of the tertairy hospitals in Singapore. The secondary objective was to determine the prevalence and current nursing management of skin tears within two selected acute medical ward...περισσότερα »
Delayed grafting for banked skin graft in lymph node flap transfer
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Delayed grafting for banked skin graft in lymph node flap transfer: Abstract Over the last decade, lymph node flap (LNF) transfer has turned out to be an effective method in the management of lymphoedema of extremities. Most of the time, the pockets created for LNF cannot be closed primarily and need to be resurfaced with split thickness skin grafts. Partial graft loss was frequently noted in these cases. The need to prevent graft loss on these iatrogenic wounds made us explore the possibility of attempting delayed skin grafting. We have herein reported our experience with delayed ... περισσότερα »
Effects of tretinoin on wound healing in aged skin
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Effects of tretinoin on wound healing in aged skin: [image: cover.gif?v=1&s=4e06cdb9cbac42b01d5dfc71] Abstract Aged and adult populations have differences in the structural, biological, and healing properties of skin. Comparative studies of healing under the influence of retinoids in both these populations are very important and, to the best of our knowledge, have not been performed to date. The purpose of this study was to compare the activities of topical tretinoin in aged and adult animal models of wound healing by secondary intention. Male aged rats (n = 7) and adult rats (n... περισσότερα »
Bisphosphonate-related osteonecrosis of the jaw in metastatic breast cancer patients
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Bisphosphonate-related osteonecrosis of the jaw in metastatic breast cancer patients: a review of 25 cases: Abstract BackgroundIntravenous bisphosphonates have been used in metastatic breast cancer patients to reduce pathologic bone fracture and bone pain. However, necrosis of the jaw has been reported in those who received intravenous bisphosphonates. Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is caused by dental extraction, dental implant surgery, and denture wearing; however, it occurs spontaneously. The purpose of this study was to report BRONJ in metastatic breas...περισσότερα »
Congenital heterotopic gastrointestinal cyst of the oral cavity
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
: report of rare case via British Journal of Oral and Maxillofacial Surgery Figures and tables 1. [image: Excision of the lesion.] 2. [image: Photomicrograph of the sample showing hyperplasic squamous stratified ...] *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Nicolás Solano, Andrés Gómez-Delgado, Luis Sarmiento, Ligia Pérez
Tumour seeding after fine-needle aspiration and core biopsy of the head and neck
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
- a systematic review via British Journal of Oral and Maxillofacial Surgery Publication date: Available online 1 February 2016 *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Keval S.V. Shah, Madan Ethunandan Although fine-needle aspiration cytology (FNAC) and core needle biopsy are essential diagnostic investigations of lumps in the head and neck, seeding along the needle track has long been a concern, and various factors have been implicated. We therefore searched the Medline database for relevant English language papers published between 1970 and 2014, excludin...περισσότερα »
Proximity of the Mandibular Canal to Teeth and Cortical Bone
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Proximity of the Mandibular Canal to Teeth and Cortical Bone: [image: gr1.sml] The proximity of the inferior alveolar canal to the mandibular molar roots may pose a risk of injury during various dental surgeries. The purpose of this study was to evaluate age-related and gender-related changes by using cone-beam computed tomography images between the roots of the second molars, mandibular cortex, and the inferior alveolar canal.
White Matter Injuries in Mild Traumatic Brain Injury and Posttraumatic Migraines: Diffusion Entropy Analysis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 24 δευτερόλεπτα
*White Matter Injuries in Mild Traumatic Brain Injury and Posttraumatic Migraines: Diffusion Entropy Analysis.* Radiology. 2016 Feb 1;:151388 Authors: Delic J, Alhilali LM, Hughes MA, Gumus S, Fakhran S Abstract Purpose To determine the performance of Shannon entropy (SE) as a diagnostic tool in patients with mild traumatic brain injury (mTBI) with posttraumatic migraines (PTMs) and those without PTMs on the basis of analysis of fractional anisotropy (FA) maps. Materials and Methods The institutional review board approved this retrospective study, with waiver of informed consent...περισσότερα »
Thickness of the Meniscal Lamellar Layer: Correlation with Indentation Stiffness and Comparison of Normal and Abnormally Thick Layers by Using Multiparametric Ultrashort Echo Time MR Imaging.
Alexandros G. SfakianakisστοHead and NeckΠριν από 24 δευτερόλεπτα
*Thickness of the Meniscal Lamellar Layer: Correlation with Indentation Stiffness and Comparison of Normal and Abnormally Thick Layers by Using Multiparametric Ultrashort Echo Time MR Imaging.* Radiology. 2016 Feb 1;:150633 Authors: Choi JY, Biswas R, Bae WC, Healey R, Im M, Statum S, Chang EY, Du J, Bydder GM, D'Lima D, Chung CB Abstract Purpose To determine the relationship between lamellar layer thickness on ultrashort echo time (UTE) magnetic resonance (MR) images and indentation stiffness of human menisci and to compare quantitative MR imaging values between two groups with... περισσότερα »
upper respiratory tract infection; +51 new citations
Alexandros G. SfakianakisστοHead and NeckΠριν από 24 δευτερόλεπτα
51 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2016/02/02 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 2 via ola Kala on Inoreader http://ift.tt/20m673f via IFTTT
Specific metabolic profiles and their relationship to insulin resistance in recent-onset type-1 and type-2 diabetes.
Alexandros G. SfakianakisστοHead and NeckΠριν από 24 δευτερόλεπτα
*Specific metabolic profiles and their relationship to insulin resistance in recent-onset type-1 and type-2 diabetes.* J Clin Endocrinol Metab. 2016 Feb 1;:jc20154133 Authors: Knebel B, Strassburger K, Szendroedi J, Kotzka J, Scheer M, Nowotny B, Müssig K, Lehr S, Pacini G, Finner H, Klüppelholz B, Giani G, Al-Hasani H, Roden M, GDS Group Abstract CONTEXT: Insulin resistance reflects inadequate insulin-mediated utilization of metabolites and predicts type 2 diabetes (T2D) but is also frequently seen in long standing type 1 diabetes (T1D) and represents a major cardiovascular ris...περισσότερα »
Vitamin D 20,000 IU per Week for Five Years does not Prevent Progression from Prediabetes to Diabetes.
Alexandros G. SfakianakisστοHead and NeckΠριν από 24 δευτερόλεπτα
*Vitamin D 20,000 IU per Week for Five Years does not Prevent Progression from Prediabetes to Diabetes.* J Clin Endocrinol Metab. 2016 Feb 1;:jc20154013 Authors: Jorde R, Sollid ST, Svartberg J, Schirmer H, Joakimsen RM, Njølstad I, Fuskevåg OM, Figenschau Y, Hutchinson MY Abstract CONTEXT: Vitamin D deficiency is associated with insulin resistance and risk of future diabetes. OBJECTIVE: To test if supplementation with vitamin D to subjects with prediabetes will prevent progression to type 2 diabetes (T2DM). DESIGN: Randomized controlled trial performed 2008 - 2015. SETTING: Clini... περισσότερα »
Variation in Location of the Mandibular Foramen/Inferior Alveolar Nerve Complex Given Anatomic Landmarks Using Cone-beam Computed Tomographic Scans
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Variation in Location of the Mandibular Foramen/Inferior Alveolar Nerve Complex Given Anatomic Landmarks Using Cone-beam Computed Tomographic Scans: [image: gr1.sml] The inferior alveolar nerve (IAN) injection is 1 of the most commonly administered and useful injections in the field of dentistry. Practitioners use intraoral anatomic landmarks, which vary greatly among patients. The objective of this study was to assist practitioners by identifying a range of normal variability within certain landmarks used in delivering IAN anesthesia.
Extracellular matrix mediators of metastatic cell colonization characterized using scaffold mimics of the pre-metastatic niche
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Extracellular matrix mediators of metastatic cell colonization characterized using scaffold mimics of the pre-metastatic niche via Acta Biomaterialia Publication date: Available online 1 February 2016 *Source:*Acta Biomaterialia Author(s): Brian A. Aguado, Jordan R. Caffe, Dhaval Nanavati, Shreyas S. Rao, Grace G. Bushnell, Samira M. Azarin, Lonnie D. Shea Metastatic tumor cells colonize the pre-metastatic niche, which is a complex microenvironment consisting partially of extracellular matrix (ECM) proteins. We sought to identify and validate novel contributors to tumor cell colonizati... περισσότερα »
An accelerated dose escalation with a grass pollen allergoid is safe and well-tolerated: a randomized open label phase II trial
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 26 δευτερόλεπτα
Abstract Background The number of injections in the dose escalation of subcutaneous immunotherapy (SCIT) is small for some currently used hypoallergenic allergoids, but can still be inconvenient to patients and can impair compliance. The aim of this trial was to compare safety and tolerability of an accelerated to the conventional dose escalation scheme of a… Continue reading An accelerated dose escalation with a grass pollen allergoid is safe and well-tolerated: a randomized open label phase II trial
Falling after epidural analgesia: lessons from obstetric anesthesia
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 26 δευτερόλεπτα
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1WZQDww via IFTTT
The effect of sevoflurane versus desflurane on postoperative catheter-related bladder discomfort in patients undergoing transurethral excision of a bladder tumour: a randomized controlled trial
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 26 δευτερόλεπτα
Abstract Purpose Catheter-related bladder discomfort (CRBD) due to an indwelling urinary catheter can cause postoperative distress, and the mechanism underlying CRBD is linked to the activation of muscarinic receptors. Inhalation of anesthetic agents, such as sevoflurane and desflurane, has differential inhibitory effects on muscarinic receptors. We aimed to compare the effect of intraoperative sevoflurane vs… Continue reading The effect of sevoflurane versus desflurane on postoperative catheter-related bladder discomfort in patients undergoing transurethral excision of a bladder tu... περισσότερα »
A “VL tube” for endotracheal intubation using video laryngoscopy
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 26 δευτερόλεπτα
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1nKlVMd via IFTTT
Successful inter-hospital transfer for extracorporeal membrane oxygenation after an amniotic fluid embolism induced cardiac arrest
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 26 δευτερόλεπτα
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1nKlVMb via IFTTT
Dexmedetomidine during total knee arthroplasty performed under spinal anesthesia decreases opioid use: a randomized-controlled trial
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 26 δευτερόλεπτα
Abstract Background It remains unclear whether the opioid-sparing effects of dexmedetomidine seen in patients undergoing general anesthesia are reproducible in patients undergoing spinal anesthesia. We hypothesized that the administration of intravenous dexmedetomidine for sedation during total knee arthroplasty under spinal anesthesia would decrease postoperative morphine consumption in the first 24 hr following surgery. Methods We… Continue reading Dexmedetomidine during total knee arthroplasty performed under spinal anesthesia decreases opioid use: a randomized-controlled trial
Local anesthetic systemic toxicity: Continuing Professional Development
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 26 δευτερόλεπτα
Abstract Purpose Regional anesthesia is enjoying a renaissance due in part to the advent of ultrasound guidance and the development of new techniques such as tissue plane blocks and local infiltration analgesia. The purpose of this Continuing Professional Development module is to provide practitioners with an understanding of the current state of knowledge surrounding local… Continue reading Local anesthetic systemic toxicity: Continuing Professional Development
Biosensors, Vol. 6, Pages 5: Developing Biosensors in Developing Countries: South Africa as a Case Study
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 26 δευτερόλεπτα
A mini-review of the reported biosensor research occurring in South Africa evidences a strong emphasis on electrochemical sensor research, guided by the opportunities this transduction platform holds for low-cost and robust sensing of numerous targets. Many of the reported publications centre on fundamental research into the signal transduction method, using model biorecognition elements, in line… Continue reading Biosensors, Vol. 6, Pages 5: Developing Biosensors in Developing Countries: South Africa as a Case Study
On Characterization of Rough Type-2 Fuzzy Sets
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 26 δευτερόλεπτα
Rough sets theory and fuzzy sets theory are important mathematical tools to deal with uncertainties. Rough fuzzy sets and fuzzy rough sets as generalizations of rough sets have been introduced. Type-2 fuzzy set provides additional degree of freedom, which makes it possible to directly handle high uncertainties. In this paper, the rough type-2 fuzzy set… Continue reading On Characterization of Rough Type-2 Fuzzy Sets
Biomedicines, Vol. 4, Pages 4: Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 26 δευτερόλεπτα
Retroviral vector gene therapy is a promising approach to treating HIV-1. However, integrated vectors are mutagens with the potential to dysregulate nearby genes and cause severe adverse side effects. Leukemia has already been a documented severe adverse event in gene therapy clinical trials for the treatment of primary immunodeficiencies. These side effects will need to… Continue reading Biomedicines, Vol. 4, Pages 4: Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy
[Aural Stimulation with Capsaicin Ointment Improved the Swallowing Function in Patients with Dysphagia: Evaluation by the SMRC Scale].
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
*[Aural Stimulation with Capsaicin Ointment Improved the Swallowing Function in Patients with Dysphagia: Evaluation by the SMRC Scale].* Nihon Jibiinkoka Gakkai Kaiho. 2015 Nov;118(11):1319-26 Authors: Kondo E, Jinnouchi O, Ohnishi H, Kawata I, Takeda N Abstract Cough and swallowing reflexes are important airway-protective mechanisms against aspiration. Angiotensin-converting enzyme (ACE) inhibitors, one of the side effects of which is cough, have been reported to reduce the incidence of aspiration pneumonia in hypertensive patients with stroke. ACE inhibitors have also been repo... περισσότερα »
Wernicke's encephalopathy after sleeve gastrectomy: Literature review.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
*Wernicke's encephalopathy after sleeve gastrectomy: Literature review.* Int J Surg Case Rep. 2016 Jan 22;20:92-95 Authors: Pardo-Aranda F, Perez-Romero N, Osorio J, Rodriguez-Santiago J, Muñoz E, Puértolas N, Veloso E Abstract OBJECTIVE: To describe a case of Wernicke's encephalopathy after laparoscopic sleeve gastrectomy. SETTING: Emergency Department and gastrointestinal surgery department. CASE REPORT: A 20-year-old man class III obesity (BMI 50.17kg/m(2)) underwent laparoscopic sleeve gastrectomy with uneventful recovery. Five weeks after surgery he was admitted in the Emerge... περισσότερα »
Primary versus secondary achalasia: A diagnostic conundrum.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Related Articles *Primary versus secondary achalasia: A diagnostic conundrum.* Trop Gastroenterol. 2015 Apr-Jun;36(2):86-95 Authors: Gupta P, Debi U, Sinha SK, Thapa BR, Prasad K Abstract A coherent distinction between primary and secondary achalasia is considerably important to clinicians. This is because the therapeutic interventions for the two are entirely different. Whilst pneumatic dilation is the standard treatment in primary achalasia, the same treatment, if instituted in malignant stenosis carries potential risk to the patient and delays appropriate therapy of the underl...περισσότερα »
[TRANSIENT PSEUDOBULBAR SYNDROME IN UNILATERAL FRONTAL OPERCULAR INFARCTS].
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Related Articles *[TRANSIENT PSEUDOBULBAR SYNDROME IN UNILATERAL FRONTAL OPERCULAR INFARCTS].* Ideggyogy Sz. 2015 Sep 30;68(9-10):339-45 Authors: Rózsa A, Torák Gyongyi, Nagy É, Kovács K, Gács G Abstract The classic anterior (frontal) opercular syndrome (Foix-Chavany-Marie sy.) is a cortical pseudobulbar palsy mainly due to bilateral lesions of anterior brain operculum. In 2000 the authors had a 70-year old female patient with acute onset of swallowing and speaking difficulty. Neurological examination established a left facial central palsy, the palsy of the tongue and the soft ... περισσότερα »
Esophageal mucosal resection versus esophagectomy: a comparative study of surgical results in patients with advanced megaesophagus.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
[image: http:--http://ift.tt/1Q7SQUV] Related Articles *Esophageal mucosal resection versus esophagectomy: a comparative study of surgical results in patients with advanced megaesophagus.* Arq Bras Cir Dig. 2015;28(1):28-31 Authors: de Oliveira GC, da Rocha RL, Coelho-Neto Jde S, Terciotti-Junior V, Lopes LR, Andreollo NA Abstract BACKGROUND: The surgical treatment of advanced megaesophagus has no consensus, being esophagectomy the more commonly used method. Since it has high morbimortality--inconvenient for benign disease -, in recent years an alternative has been introduced: th...περισσότερα »
Minimal endoscopic changes in non-erosive reflux disease.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
[image: http:--http://ift.tt/1Q7SQUV] Related Articles *Minimal endoscopic changes in non-erosive reflux disease.* Arq Bras Cir Dig. 2015;28(1):20-3 Authors: Ratin AC, Orso IR Abstract BACKGROUND: Gastroesophageal reflux disease is an increasingly common condition worldwide causing a considerable economic impact. More than half the patients with clinical symptoms of reflux disease display no mucosal erosions on esophagogastroduodenoscopy, making it impossible to confirm the diagnosis without further investigations. AIM: To evaluate the correlation between minimal endoscopic change...περισσότερα »
Clinical, metabolic, and psychological characteristics in patients with gastroesophageal reflux disease overlap with irritable bowel syndrome.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Clinical, metabolic, and psychological characteristics in patients with gastroesophageal reflux disease overlap with irritable bowel syndrome.* Eur J Gastroenterol Hepatol. 2015 May;27(5):516-22 Authors: Hsu CS, Liu TT, Wen SH, Wang CC, Yi CH, Chen JH, Lei WY, Orr WC, Fabio P, Chen CL Abstract OBJECTIVES: Gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS) are highly prevalent in the general population, with significant symptom overlap, whereas the interaction between both remains poorly und...περισσότερα »
Toxic cerebellar syndrome due to methotrexate.
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Toxic cerebellar syndrome due to methotrexate.* Pract Neurol. 2015 Jun;15(3):214-5 Authors: Kinzel O, Verma RK, Wiest R, Mattle HP PMID: 25814514 [PubMed - indexed for MEDLINE] from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1Sq1SPT via IFTTT
Downregulating aberrant motor evoked potential synergies of the lower extremity post stroke during TMS of the contralesional hemisphere
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
[image: alertIcon.gif] Publication date: Available online 1 February 2016 *Source:*Brain Stimulation Author(s): Andrew Q Tan, Jon Shemmell, Yasin Y Dhaher BackgroundGrowing evidence demonstrates unique synergistic signatures in the lower limb (LL) post-stroke, with specific across-plane and across-joint representations. While the inhibitory role of the ipsilateral hemisphere in the upper limb (UL) has been widely reported, examination of the contralesional hemisphere (CON-H) in modulating LL expressions of synergies following stroke is lacking.ObjectiveWe hypothesize that stimulatio... περισσότερα »
Brain Biocompatibility and Microglia Response Towards Engineered Self-Assembling (RADA)4 Nanoscaffolds
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Brain Biocompatibility and Microglia Response Towards Engineered Self-Assembling (RADA)4 Nanoscaffolds via Acta Biomaterialia Publication date: Available online 2 February 2016 *Source:*Acta Biomaterialia Author(s): K.M. Koss, M.A. Churchward, A.T. Nguyen, J.Y. Yager, K.G. Todd, L.D. Unsworth (RADA)4-based nanoscaffolds have many inherent properties making them amenable to tissue engineering applications: ease of synthesis, ease of customization with bioactive moieties, and amenable for in situ nanoscaffold formation. There is a dearth in the literature on their biocompatibility in br... περισσότερα »
Sjögren’s Syndrome. Dry mouth is not a trivial symptom for Sjögren’s Syndrome sufferers; it has considerable impact on their day-to-day lives. Healthcare professionals need to understand patients as individuals in their environment in order to be part of the Sjögren’s journey.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
The lived experience of Sjögren’s Syndrome: Abstract BackgroundSjögren’s Syndrome is an autoimmune exocrinopathy characterised by lymphocytic infiltration of exocrine glands in multiple sites, with dry mouth as a primary presenting symptom. Although quantitative studies have shown the negative impact of both dry mouth and Sjögren’s Syndrome on patients’ quality of life, no qualitative diary and interview study has been undertaken to examine the lived experience of dry mouth for Sjögren’s Syndrome sufferers. The aim of this qualitative study was to provide clinicians with insight i...περισσότερα »
Cleaning Methods for Zirconia Following Salivary Contamination
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Cleaning Methods for Zirconia Following Salivary Contamination: Abstract Purpose To determine the best method of cleaning saliva-contaminated zirconia in preparation for resin bonding. Material and Methods Flat blocks of zirconia were particle abraded with aluminum oxide and divided into eight groups (n = 10). Groups 1 to 4 were first treated with one coat of an MDP primer (Z-prime Plus) and groups 5 to 8 were left untreated. A thin coat of fresh whole saliva was painted on all specimens (except the control, group 1) and left in contact for 3 minutes. The specimens were then cleaned... περισσότερα »
Temporal-spatial gait parameters and neurodevelopment in very-low-birth-weight preterm toddlers
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
at 18–22 months via Gait & Posture Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Katelyn Cahill-Rowley, Jessica Rose Children born preterm with very-low birth-weight (VLBW) have increased risk of motor impairment. Early identification of impairment guides treatment to improve long-term function. Temporal-spatial gait parameters are an easily-recorded assessment of gross motor function. The objective of this study was to characterize preterm toddlers’ gait and its relationship with neurodevelopment. Velocity, cycle time, step width, step length and time as...περισσότερα »
Maturation of Mechanical Impedance of the Skin-Covered Skull: Implications for Soft Band Bone-Anchored Hearing Systems Fitted in Infants and Young Children.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Maturation of Mechanical Impedance of the Skin-Covered Skull: Implications for Soft Band Bone-Anchored Hearing Systems Fitted in Infants and Young Children.: Objectives: Little is known about the maturational changes in the mechanical properties of the skull and how they might contribute to infant-adult differences in bone conduction hearing sensitivity. The objective of this study was to investigate the mechanical impedance of the skin-covered skull for different skull positions and contact forces for groups of infants, young children, and adults. These findings provide a better un... περισσότερα »
A thin line between Meniere's disease and spontaneous intracranial hypotension syndrome.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
A thin line between Meniere's disease and spontaneous intracranial hypotension syndrome Authors: Botica I, Vrca A, Špero M, Šubarić M, Carić T, Vrca Botica M, Kovačić J, Makaruha K, Roglić A Abstract Aim To point out the similarity of Meniere disease and spontaneous intracranial hypotension and difference of their treatment. Methods A case of a 54-year-old male patient with previously diagnosed Meniere's disease and newly diagnosed spontaneous intracranial hypotension syndrome is presented. Additional neuroradiological examination, Brain contrast-enhanced MRI and MR myelography we...περισσότερα »
Adjuvant Radioactive iodine 131 ablation in papillary microcarcinoma of thyroid: Saudi Arabian experience
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
Erratum to: Adjuvant Radioactive iodine 131 ablation in papillary microcarcinoma of thyroid: Saudi Arabian experience: Unfortunately, the original version of this article [1] contained two errors. The title incorrectly referred to “radioactive iodine 133” instead of “radioactive iodine 131” and contained unnecessary quotation marks. The title has been updated in the original article and is also correctly included in full in this erratum. Reference 1. 1. Al-Qahtani KH, Al Asiri M, Tunio MA, Aljohani NJ, Bayoumi Y, Fatani H, et al. Adjuvant Radioactive iodine 131 ablatio... περισσότερα »
Brief electrical stimulation after facial nerve transection and neurorrhaphy: a randomized prospective animal study
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Brief electrical stimulation after facial nerve transection and neurorrhaphy: a randomized prospective animal study: Abstract BackgroundRecent studies have examined the effects of brief electrical stimulation (BES) on nerve regeneration, with some suggesting that BES accelerates facial nerve recovery. However, the facial nerve outcome measurement in these studies has not been precise or accurate. The objective of this study is to assess the effect of BES on accelerating facial nerve functional recovery from a transection injury in the rat model. MethodsA prospective randomized ... περισσότερα »
Cochlear implant and congenital cholesteatoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Cochlear implant and congenital cholesteatoma: Abstract BackgroundThe occurence of cholesteatoma and cochlear implant is rare. Secondary cholesteatomas may develop as a result of cochlear implant surgery. Primarily acquired cholesteatoma is not typically associated with congenital sensorineural hearing loss or cochlear implant in children. The occurrence of congenital cholesteatoma during cochlear implant surgery has never been reported before, partly because all patients are preoperatively submitted to imaging studies which can theoretically exclude the disease. Case presentati... περισσότερα »
New oral anticoagulants – a guide for ENT surgeons
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Review ArticleNew oral anticoagulants – a guide for ENT surgeonsS Kumara1 c1 and R Moorthya2 a1 ENT Department, John Radcliffe Hospital, Oxford, UK a2 ENT Department, Wexham Park Hospital, Slough, UK Abstract Background: New oral anticoagulants have been developed to overcome the perceived disadvantages of more traditional anticoagulants such as heparin and warfarin, and their use amongst ENT patients have been increasing. Objectives: This review article aims to discuss the mechanism of action of new oral anticoagulants, when they should be used and a protocol for their use, in both th... περισσότερα »
Comparison of the protective effects of intratympanic dexamethasone and methylprednisolone against cisplatin-induced ototoxicity
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Comparison of the protective effects of intratympanic dexamethasone and methylprednisolone against cisplatin-induced ototoxicity: Research Articles H E Özel, F Özdoğan, S G Gürgen, E Esen, S Genç, A Selçuk The Journal of Laryngology & Otology,FirstView Article(s), 10 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] Main ArticleComparison of the protective effects of intratympanic dexamethasone and methylprednisolone against cisplatin-induced ototoxicityH E Özela1 c1, F Özdoğana1, S G Gürgena2, E Esena1, S Gença1 and A Selçuka1 a1 De... περισσότερα »
The vomeronasal organ
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Main ArticleThe vomeronasal organ – incidence in a Bulgarian population G Stoyanova1 c1, K Monevaa2, N Sapundzhieva2 and A B Toncheva1 a1 Department of Anatomy, Histology and Embryology, Medical University - Varna “Prof. Dr. Paraskev Stoyanov”, Varna, Bulgaria a2 Division of Otorhinolaryngology, Department of Neurosurgery and ENT Diseases, Medical University - Varna “Prof. Dr. Paraskev Stoyanov”, Varna, Bulgaria Abstract Background: The vomeronasal organ is an accessory olfactory organ found in vertebrates that specialises in the chemoreception of pheromones. This study aimed to explor... περισσότερα »
Long noncoding RNA, tissue differentiation-inducing nonprotein coding RNA is upregulated and promotes development of esophageal squamous cell carcinoma
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 33 δευτερόλεπτα
Long noncoding RNA, tissue differentiation-inducing nonprotein coding RNA is upregulated and promotes development of esophageal squamous cell carcinoma: Summary Esophageal squamous cell carcinoma (ESCC) is one of the major causes of cancer death worldwide, especially in Eastern Asia. Due to the poor prognosis, it is necessary to further dissect the underlying mechanisms and explore therapeutic targets of ESCC. Recently, studies show that long noncoding RNAs (lncRNAs) have critical roles in diverse biological processes, including tumorigenesis. Increasing evidence indicates that som... περισσότερα »
Update on Select Benign Mesenchymal and Meningothelial Sinonasal Tract Lesions
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 33 δευτερόλεπτα
Update on Select Benign Mesenchymal and Meningothelial Sinonasal Tract Lesions: AbstractSeveral benign and malignant mesenchymal and meningothelial lesions may preferentially affect or extend into the sinonasal tract. Glomangiopericytoma (GPC, formerly sinonasal-type hemangiopericytoma) is a specific tumor with a predilection to the sinonasal tract. Sinonasal tract polyps with stromal atypia (antrochoanal polyp) demonstrate unique histologic findings in the sinonasal tract. Juvenile nasopharyngeal angiofibroma (JNA) arises from specialized tissue in this location. Meningioma may d... περισσότερα »
Sinonasal Tract Lesions
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα
Benign Mesenchymal and Meningothelial Sinonasal Tract Lesions Update on Select Benign Mesenchymal and Meningothelial Sinonasal Tract Lesions: AbstractSeveral benign and malignant mesenchymal and meningothelial lesions may preferentially affect or extend into the sinonasal tract. Glomangiopericytoma (GPC, formerly sinonasal-type hemangiopericytoma) is a specific tumor with a predilection to the sinonasal tract. Sinonasal tract polyps with stromal atypia (antrochoanal polyp) demonstrate unique histologic findings in the sinonasal tract. Juvenile nasopharyngeal angiofibroma (JNA) arise... περισσότερα »
Germline RET mutation carriers in Japanese patients with apparently sporadic medullary thyroid carcinoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα
: A single institution experience via Auris Nasus Larynx Publication date: Available online 1 February 2016 *Source:*Auris Nasus Larynx Author(s): Minoru Kihara, Akira Miyauchi, Kana Yoshioka, Hitomi Oda, Ayako Nakayama, Hisanori Sasai, Tomonori Yabuta, Hiroo Masuoka, Takuya Higashiyama, Mitsuhiro Fukushima, Yasuhiro Ito, Kaoru Kobayashi, Akihiro Miya ObjectiveGenetic testing for RET germline mutation can be useful to distinguish whether a patient with medullary thyroid carcinoma (MTC) is genuinely sporadic or hereditary. Conducting a routine preoperative germline RET genetic screenin...περισσότερα »
Detection of Helicobacter pylori in Nasal Polyps
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 36 δευτερόλεπτα
Detection of Helicobacter pylori in Nasal Polyps: AbstractTo detect the presence of *Helicobacter pylori* in nasal polyps. A case–control study was conducted enrolling 35 patients with nasal polyps (cases) and patients undergoing septoplasty (controls). Fresh tissue samples were used for urea broth test and imprint cytology, while formalin fixed tissue sections were used for morphology, special stains and immunohistochemistry for *H. pylori*. Fresh stool samples from both groups were tested to correlate the gastrointestinal status. *H. pylori* was detected in 40.0 % (14/35) of case... περισσότερα »
Low-Grade Epithelial Proliferations of the Sinonasal Tract
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Low-Grade Epithelial Proliferations of the Sinonasal Tract: AbstractLow-grade epithelial proliferations of the sinonasal tract include Schneiderian papillomas, respiratory epithelial adenomatoid hamartoma, seromucinous hamartoma and low-grade non-intestinal adenocarcinoma. There is considerable overlap in their clinical presentation, endoscopic appearance, and imaging features. Although well-described diagnostic criteria exist, a definitive diagnosis may be difficult to reach on a small biopsy. Schneiderian papillomas are divided into fungiform, inverted, and oncocytic types, each ... περισσότερα »
Sinonasal Squamous Cell Carcinoma
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Sinonasal Squamous Cell Carcinoma: A Review with Emphasis on Emerging Histologic Subtypes and the Role of Human Papillomavirus: AbstractThe sinonasal tract is one of the least frequent sites for squamous cell carcinoma in the head and neck. However, it is still a complex tumor type for pathologists because there are numerous histologic variants with unusual morphologic features, several non-squamous carcinomas in the differential diagnosis that can have similar morphology and even squamous differentiation, and because of the increasing recognition of human papillomavirus (HPV) in a... περισσότερα »
Neuroendocrine Neoplasms of the Sinonasal Tract: Neuroendocrine Carcinomas and Olfactory Neuroblastoma
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Neuroendocrine Neoplasms of the Sinonasal Tract: Neuroendocrine Carcinomas and Olfactory Neuroblastoma: AbstractNeuroendocrine neoplasms (NENs) can occur in organs or tissues that do not contain neuroendocrine cells normally and do not necessarily imply embryologic derivation from the neuroectoderm; but rather reflect a shared phenotype characterized by the expression of multiple genes encoding both endocrine and neuronal features. NENs are rare in the sinonasal tract and are subdivided into epithelial and neural subtypes based on the presence of keratins or neurofilaments, respect... περισσότερα »
Radiologic Features of Sinonasal Tumors
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Radiologic Features of Sinonasal Tumors: AbstractImaging evaluation of sinonasal tumors is most often conducted with computed tomography, which excels at identifying the effects of these masses on adjacent osseous structures, and magnetic resonance imaging that is ideal for distinguishing pathologic masses from mucosal thickening and fluid that are common in the sinonasal spaces and depicting extension into the surrounding soft tissues, orbits, and intracranial compartment. Accordingly, the two studies are complementary exams and both are commonly utilized in the assessment of thes... περισσότερα »
Non-infectious Inflammatory Lesions of the Sinonasal Tract
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Non-infectious Inflammatory Lesions of the Sinonasal Tract: AbstractThis review covers the histopathology and pathogenesis of non-infectious inflammatory diseases of the sinonasal tract, in particular, sarcoidosis, granulomatous vasculitides Wegener, Churg–Strauss), relapsing polychondritis, eosinophilic angiocentric fibrosis, chronic rhinosinusitis and nasal perforations. Molecular associations and mechanisms are emphasised to assist pathologists to put their observations into the context of clinical, genetic and environmental influences on patients’ diseases.
Endonasal Endoscopic Surgery in the Management of Sinonasal and Anterior Skull Base Malignancies
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Endonasal Endoscopic Surgery in the Management of Sinonasal and Anterior Skull Base Malignancies: AbstractSinonasal malignancies represent a rare subset of tumors with a wide variety of histopathologic diagnoses and overall poor prognosis. These tumors tend to have an insidious onset with non-specific symptoms which often leads to delayed diagnosis and advanced local disease at presentation. The principal goal of surgery is to obtain a negative margin resection. Open craniofacial techniques are well established in the management of sinonasal malignancies and remain the treatment of...περισσότερα »
Newly Described Tumor Entities in Sinonasal Tract Pathology
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Newly Described Tumor Entities in Sinonasal Tract Pathology: AbstractSurgical pathology of the sinonasal tract (nasal cavity and paranasal sinuses) is extremely challenging due in part to the tremendous diversity of tumor types that may arise in this region. Compounding the difficulty, a number of new sinonasal tumor entities have been recently described, and pathologists may not yet be familiar with these neoplasms. This manuscript will review the clinicopathologic features of some of the newly described sinonasal tumor types: NUT midline carcinoma, HPV-related carcinoma with aden...περισσότερα »
Hematolymphoid Lesions of the Sinonasal Tract
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 39 δευτερόλεπτα
Hematolymphoid Lesions of the Sinonasal Tract: AbstractHematolymphoid neoplasms of the sinonasal tract are rare and the majority represents non-Hodgkin lymphomas. This review will focus on morphologic, immunophenotypic, and genetic characteristics of the most common types of non-Hodgkin lymphoma, namely diffuse large B cell lymphoma and extranodal natural killer/T-cell lymphoma, nasal type, but also include the discussion of less frequent other hematolymphoid entities, such as extranodal plasmacytomas and Rosai–Dorfman disease.
Sinonasal Adenocarcinoma: Update on Classification, Immunophenotype and Molecular Features
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 39 δευτερόλεπτα
Sinonasal Adenocarcinoma: Update on Classification, Immunophenotype and Molecular Features: AbstractAdenocarcinomas of the sinonasal tract may originate from respiratory surface epithelium or the underlying seromucinous glands. These malignancies are divided into salivary-type adenocarcinomas and non-salivary-type adenocarcinomas. The latter are further divided into intestinal-type and nonintestinal-type adenocarcinomas. This review provides an update on tumor classification, differential diagnostic considerations and molecular features, as well as new adenocarcinoma entities in t... περισσότερα »
Sinonasal Round Cell Undifferentiated Tumors
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 39 δευτερόλεπτα
An Update on Sinonasal Round Cell Undifferentiated Tumors: AbstractThe sinonasal cavities host a wide variety of undifferentiated malignancies with round cell morphology, including neoplasms of epithelial, mesenchymal, neuroectodermal, and hematolymphoid lineage. The differential diagnosis may be difficult, especially in small biopsy material, due to overlapping morphology, but their correct classification is clinically relevant. The aim of this review is to provide practical guidelines for the differential diagnosis of these malignancies, with emphasis on recently described entiti...περισσότερα »
Biological modelling of the radiation dose escalation effect of regional hyperthermia in cervical cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Background Locoregional hyperthermia combined with radiotherapy significantly improves locoregional control and overall survival for cervical tumors compared to radiotherapy alone. In this study biological modelling is applied to quantify the effect of radiosensitization for three cervical cancer patients to evaluate the improvement in equivalent dose for the combination treatment with radiotherapy and hyperthermia. Methods […]
Evaluation of a dedicated brain metastases treatment planning optimization for radiosurgery: a new treatment paradigm?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Purpose To investigate the feasibility of a novel dedicated treatment planning solution, to automatically target multiple brain metastases with a single isocenter and multiple inversely-optimized dynamic conformal arcs (DCA), and to benchmark it against the well-established multiple isocenter DCA (MIDCA) and volumetric modulated arc therapy (VMAT) approaches. Material and Methods Ten previously treated patients […]
A practical review of magnetic resonance imaging for the evaluation and management of cervical cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Cervical cancer is a leading cause of mortality in women worldwide. Staging and management of cervical cancer has for many years been based on clinical exam and basic imaging such as intravenous pyelogram and x-ray. Unfortunately, despite advances in radiotherapy and the inclusion of chemotherapy in the standard plan for locally advanced disease, local […]
Falling after epidural analgesia: lessons from obstetric anesthesia
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WZQDww via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The effect of sevoflurane versus desflurane on postoperative catheter-related bladder discomfort in patients undergoing transurethral excision of a bladder tumour: a randomized controlled trial
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Purpose Catheter-related bladder discomfort (CRBD) due to an indwelling urinary catheter can cause postoperative distress, and the mechanism underlying CRBD is linked to the activation of muscarinic receptors. Inhalation of anesthetic agents, such as sevoflurane and desflurane, has differential inhibitory effects on muscarinic receptors. We aimed to compare the effect of intraoperative sevoflurane vs […]
A “VL tube” for endotracheal intubation using video laryngoscopy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1nKlVMd via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Successful inter-hospital transfer for extracorporeal membrane oxygenation after an amniotic fluid embolism induced cardiac arrest
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1nKlVMb via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Dexmedetomidine during total knee arthroplasty performed under spinal anesthesia decreases opioid use: a randomized-controlled trial
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Background It remains unclear whether the opioid-sparing effects of dexmedetomidine seen in patients undergoing general anesthesia are reproducible in patients undergoing spinal anesthesia. We hypothesized that the administration of intravenous dexmedetomidine for sedation during total knee arthroplasty under spinal anesthesia would decrease postoperative morphine consumption in the first 24 hr following surgery. Methods We […]
Local anesthetic systemic toxicity: Continuing Professional Development
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Purpose Regional anesthesia is enjoying a renaissance due in part to the advent of ultrasound guidance and the development of new techniques such as tissue plane blocks and local infiltration analgesia. The purpose of this Continuing Professional Development module is to provide practitioners with an understanding of the current state of knowledge surrounding local […]
Culture, Medicine, and Psychiatry
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/205sfcO via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Journal of Cardiothoracic Surgery
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SBczNK via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Head and neck paragangliomas: diffusion weighted and dynamic contrast enhanced magnetic resonance imaging characteristics
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Background To determine the feature values of head and neck paragangliomas on diffusion-weighted imaging (DWI) and dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI). Methods Patients with primary head and neck paraganglioma who underwent both DWI and DCE-MRI before treatment between January 2010 and June 2013 were identified. Two radiologists assessed apparent diffusion coefficient […]
Development of novel in vitro human digestion systems for screening the bioavailability and digestibility of foods
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Publication date: April 2016 Source:Journal of Functional Foods, Volume 22 Author(s): Seung-Jae Lee, Seung Yuan Lee, Myung-Sub Chung, Sun Jin Hur The in vitro models employed have included all steps involved in digestion upon passage through the mouth, stomach, small intestine, and the colon. Importantly, enterobacter bacteria (Escherichia coli and Lactobacillus casei) are included to […]
Pu-erh tea attenuates smoking-induced foam cell formation through inhibition of the α9-nicotinic-acetylcholine receptor expression in monocytes: An ex vivo study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Publication date: April 2016 Source:Journal of Functional Foods, Volume 22 Author(s): Li-Ching Chen, Ming-Yao Chen, Shih-Hsin Tu, Min-Hsiung Pan, Chih-Yu Lo, Chi-Tang Ho, Chih-Hsiung Wu, Yuan-Soon Ho To assess whether drinking tea can effectively prevent smoking-induced atherosclerosis, a clinical trial ex vivo study was performed. The volunteers were randomly allocated to two groups (n = 55 per […]
The composition, antioxidant and antiproliferative capacities of phenolic compounds extracted from tartary buckwheat bran Fagopyrum tartaricum (L.) Gaerth
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Publication date: April 2016 Source:Journal of Functional Foods, Volume 22 Author(s): Fuhua Li, Xiaoli Zhang, Shaojie Zheng, Keke Lu, Guohua Zhao, Jian Ming Tartary buckwheat bran [Fagopyrum tartaricum (L.) Gaerth, FG], a major by-product of tartary buckwheat flour production, may serve as a natural source of phenolic compounds with potential antioxidant activity. In this study, […]
Fibula Jaw in a Day: State of the Art in Mandibular Reconstruction. A Report of 3 Cases
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Publication date: Available online 1 February 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Mohammed Qaisi, Harold Kolodney, Gary Swedenburg, Ravi Chandran, Ronald Caloss Microvascular free tissue transfer has been one of the greatest milestones in reconstruction of the mandible and maxilla after tumor ablative surgery. Although fibula free flap reconstruction allows for immediate bony reconstruction, dental rehabilitation usually requires 6-12 months before it is completed. This can have a huge psychological impact on patients as they go without teeth during th... περισσότερα »
Does the rate of distraction or type of distractor affect the outcome of mandibular distraction in children with micrognathia?
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Publication date: Available online 2 February 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Omar Breik, David Tivey, Kandiah Umapathysivam, Peter Anderson BackgroundA variety of surgical protocols are available in the literature for performing mandibular distraction. This study aims to determine the ideal rate of distraction and compare outcomes between internal and external distractors in children and infants with upper airway obstruction secondary to micrognathia.MethodsA systematic review was performed. The databases searched included PubMed, Embase, Scopus, W... περισσότερα »
The Predictive Value of Resonance Frequency Analysis Measurements in the Surgical Placement and Loading of Endosseous Implants
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Publication date: Available online 1 February 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Serge Baltayan, Joan Pi-Anfruns, Tara Aghaloo, Peter K. Moy PurposeThe purpose of this study was to investigate the predictive value of resonance frequency analysis (RFA) in assessing implant survival. This was accomplished by determining the correlation between implant stability quotients (ISQ) and implant survival following different placement staging (one-stage vs. two-stage) and loading (early vs. traditional) protocols.Materials and MethodsA retrospective study was pe... περισσότερα »
An In Vitro Study of Condylar Displacement Caused by Interocclusal Records: Influence of Recording Material, Storage Time, and Recording Technique
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Abstract Purpose To evaluate the condylar displacement after mounting working casts using different interocclusal recording materials and to analyze the influence of the storage time and the recording technique on the displacement caused by the interocclusal record. Materials and Methods Eight interocclusal records were made in each of the following groups: G1: Aluwax (aluminum wax), G2: Beauty Pink wax (hydrocarbon wax compound), G3: Futar D Fast, G4: Futar Scan (G3, G4: vinylpolysiloxane), G5: Ramitec (polyether), G6: LuxaBite (composite resin based on bis-acryl), G7: LuxaBite...περισσότερα »
Downregulating aberrant motor evoked potential synergies of the lower extremity post stroke during TMS of the contralesional hemisphere
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
[image: alertIcon.gif] Publication date: Available online 1 February 2016 *Source:*Brain Stimulation Author(s): Andrew Q Tan, Jon Shemmell, Yasin Y Dhaher BackgroundGrowing evidence demonstrates unique synergistic signatures in the lower limb (LL) post-stroke, with specific across-plane and across-joint representations. While the inhibitory role of the ipsilateral hemisphere in the upper limb (UL) has been widely reported, examination of the contralesional hemisphere (CON-H) in modulating LL expressions of synergies following stroke is lacking.ObjectiveWe hypothesize that stimulatio... περισσότερα »
Recurrent bacteremia with different strains of Streptococcus pyogenes in an immunocompromised child
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 1 February 2016 Source:Journal of Infection and Chemotherapy Author(s): Takuya Hattori, Masaaki Minami, Kotaro Narita, Tomohiko Nakata, Seiko Itomi, Kinya Kubota, Teruaki Oya, Hideki Nishiyama, Hideki Kato, Norihiro Yuasa We report an immunocompromised child who experienced two episodes of bacteremia due to Streptococcus pyogenes. Random amplification of polymorphic DNA profiles, emm […]
Beta-cell mass in non-diabetic autoantibody-positive subjects: an analysis based on the nPOD database.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Beta-cell mass in non-diabetic autoantibody-positive subjects: an analysis based on the nPOD database.* J Clin Endocrinol Metab. 2016 Feb 1;:jc20153756 Authors: Diedisheim M, Mallone R, Boitard C, Larger E Abstract CONTEXT: Little information is available about beta-cell mass in antibody-positive (Ab+) non-diabetic subjects. OBJECTIVE: We have investigated whether the publicly available virtual slides of the nPOD project can be used to assess beta-cell mass and distribution in non-diabetic Ab- and Ab+ subjects and in patients with recent onset type 1 diabetes (T1D). SUBJECTS AND... περισσότερα »
Impaired Insulin Suppression of VLDL-Triglyceride Kinetics in Non-alcoholic Fatty Liver Disease.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Impaired Insulin Suppression of VLDL-Triglyceride Kinetics in Non-alcoholic Fatty Liver Disease.* J Clin Endocrinol Metab. 2016 Feb 1;:jc20153476 Authors: Poulsen MK, Nellemann B, Stødkilde-Jørgensen H, Pedersen SB, Grønbæk H, Nielsen S Abstract CONTEXT: Non-alcoholic fatty liver disease (NAFLD) is associated with glucose and lipid metabolic abnormalities. However, insulin suppression of VLDL-triglyceride (VLDL-TG) kinetics is not fully understood. OBJECTIVE: To determine VLDL-TG, glucose and palmitate kinetics during fasting and hyperinsulinemia in men with (NAFLD+) and without...περισσότερα »
Obesity-associated inflammation induces microRNA-155 expression in adipocytes and adipose tissue: outcome on adipocyte function.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Obesity-associated inflammation induces microRNA-155 expression in adipocytes and adipose tissue: outcome on adipocyte function.* J Clin Endocrinol Metab. 2016 Feb 1;:jc20153410 Authors: Karkeni E, Astier J, Tourniaire F, El Abed M, Romier B, Gouranton E, Lin W, Borel P, Salles J, Walrand S, Ye J, Landrier JF Abstract CONTEXT: Obesity alters adipose tissue metabolic and endocrine functions and causes a chronic local and systemic low-grade inflammatory state to develop, generating obesity-associated complications. In the last decade, many entities contributing to and regulating t...περισσότερα »
Management of sinonasal undifferentiated carcinoma with intracerebral invasion: Clinical experience at a single institution and review of the literature.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Management of sinonasal undifferentiated carcinoma with intracerebral invasion: Clinical experience at a single institution and review of the literature.* Ear Nose Throat J. 2016 Jan;95(1):23-28 Authors: Zielinski V, Laban S, Tribius S, Schafhausen P, Veldhoen S, Knecht R, Clauditz T, Muenscher A Abstract Sinonasal undifferentiated carcinoma (SNUC) represents less than 1% of all malignancies. Most of the tumors are diagnosed at an advanced stage, when they have already invaded neighboring tissue structures. We describe the cases of 2 patients with a substantial intracerebral ex... περισσότερα »
Four cystic parathyroid adenomas in a 71-year-old man.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Four cystic parathyroid adenomas in a 71-year-old man.* Ear Nose Throat J. 2016 Jan;95(1):21-22 Authors: Bann DV, Goldenberg D PMID: 26829681 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1ma8mUp via IFTTT
Hemangioma.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Hemangioma.* Ear Nose Throat J. 2016 Jan;95(1):19-20 Authors: Kita AE, Long JL PMID: 26829680 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1o1LRCX via IFTTT
[Old phenotype and new genotypes. Pituitary adenomas].
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *[Old phenotype and new genotypes. Pituitary adenomas].* Rev Med Liege. 2015 Nov;70(11):569-74 Authors: Gérard C, Jedidi H, Petrossians P, Krzesinski F, Daly A, Beckers A Abstract Gigantism and acromegaly, usually caused by a pituitary adenoma linked inappropriate secretion of growth hormone (GH), are generally considered as very rare diseases, even if, according to some authors, their cumulative prevalence is about 1/5000. Starting from the historical case of a giant from Liège we shall describe the different types of GH pituitary adenomas and their pathophysiol... περισσότερα »
Good's syndrome with increasing γδ T-lymphocyte subpopulation: A case report.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Good's syndrome with increasing γδ T-lymphocyte subpopulation: A case report.* Vojnosanit Pregl. 2015 Nov;72(11):1039-43 Authors: Tadić D, Marković O, Kraguljac-Kurtović N, Drobnjak-Tomasek O Abstract INTRODUCTION: Good's syndrome is a rare cause of adult-onset immunodeficiency associated with thymoma. Good's syndrome should be considered in patients older than 40 years with the history of frequent infections. An abnormal immunoglobulin profile needs further investigation and flow cytometry which is crucial for establishing the diagno- sis of Good's syndrome. C...περισσότερα »
Non-functional parathyroid cyst--diagnostic pitfall: A case-report.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Non-functional parathyroid cyst--diagnostic pitfall: A case-report.* Vojnosanit Pregl. 2015 Nov;72(11):1032-4 Authors: Polovina SP, Andjelković Z, Micić DD Abstract INTRODUCTION: Parathyroid cysts are relative rare and they may be misdiagnosed with thyroid nodules. Parathyroid cysts are characterized by elevated level of parathyroid hormone (PTH) in cystic fluid. CASE REPORT. We reported about middle-aged woman with palpable node in the left thyroid lobe. Ultrasound showed anechoic 40 x 25 mm lesion in the left thyroid lobe. Fine needle aspiration (FNA) obtained... περισσότερα »
Fibula Jaw in a Day: State of the Art in Mandibular Reconstruction. A Report of 3 Cases
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 1 February 2016 Source:Journal of Oral and Maxillofacial Surgery Author(s): Mohammed Qaisi, Harold Kolodney, Gary Swedenburg, Ravi Chandran, Ronald Caloss Microvascular free tissue transfer has been one of the greatest milestones in reconstruction of the mandible and maxilla after tumor ablative surgery. Although fibula free flap reconstruction allows for immediate bony… Continue reading Fibula Jaw in a Day: State of the Art in Mandibular Reconstruction. A Report of 3 Cases
Does the rate of distraction or type of distractor affect the outcome of mandibular distraction in children with micrognathia?
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 2 February 2016 Source:Journal of Oral and Maxillofacial Surgery Author(s): Omar Breik, David Tivey, Kandiah Umapathysivam, Peter Anderson BackgroundA variety of surgical protocols are available in the literature for performing mandibular distraction. This study aims to determine the ideal rate of distraction and compare outcomes between internal and external distractors in… Continue reading Does the rate of distraction or type of distractor affect the outcome of mandibular distraction in children with micrognathia?
The Predictive Value of Resonance Frequency Analysis Measurements in the Surgical Placement and Loading of Endosseous Implants
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 1 February 2016 Source:Journal of Oral and Maxillofacial Surgery Author(s): Serge Baltayan, Joan Pi-Anfruns, Tara Aghaloo, Peter K. Moy PurposeThe purpose of this study was to investigate the predictive value of resonance frequency analysis (RFA) in assessing implant survival. This was accomplished by determining the correlation between implant stability quotients (ISQ)… Continue reading The Predictive Value of Resonance Frequency Analysis Measurements in the Surgical Placement and Loading of Endosseous Implants
Head and neck paragangliomas: diffusion weighted and dynamic contrast enhanced magnetic resonance imaging characteristics
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Abstract Background To determine the feature values of head and neck paragangliomas on diffusion-weighted imaging (DWI) and dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI). Methods Patients with primary head and neck paraganglioma who underwent both DWI and DCE-MRI before treatment between January 2010 and June 2013 were identified. Two radiologists assessed apparent diffusion coefficient… Continue reading Head and neck paragangliomas: diffusion weighted and dynamic contrast enhanced magnetic resonance imaging characteristics
Germline RET mutation carriers in Japanese patients with apparently sporadic medullary thyroid carcinoma: A single institution experience
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 1 February 2016 Source:Auris Nasus Larynx Author(s): Minoru Kihara, Akira Miyauchi, Kana Yoshioka, Hitomi Oda, Ayako Nakayama, Hisanori Sasai, Tomonori Yabuta, Hiroo Masuoka, Takuya Higashiyama, Mitsuhiro Fukushima, Yasuhiro Ito, Kaoru Kobayashi, Akihiro Miya ObjectiveGenetic testing for RET germline mutation can be useful to distinguish whether a patient with medullary thyroid carcinoma… Continue reading Germline RET mutation carriers in Japanese patients with apparently sporadic medullary thyroid carcinoma: A single institution experience
ICRP 129 and Cone Beam Computed Tomography
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 2 February 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): James R. Geist from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1JV6TwZ via IFTTT
The vomeronasal organ – incidence in a Bulgarian population
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Research Articles G Stoyanov, K Moneva, N Sapundzhiev, A B Tonchev The Journal of Laryngology & Otology,FirstView Article(s), 4 pages Abstract from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/205kB21 via IFTTT
Comparison of the protective effects of intratympanic dexamethasone and methylprednisolone against cisplatin-induced ototoxicity
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Research Articles H E Özel, F Özdoğan, S G Gürgen, E Esen, S Genç, A Selçuk The Journal of Laryngology & Otology,FirstView Article(s), 10 pages Abstract from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1SB2AYZ via IFTTT
New oral anticoagulants – a guide for ENT surgeons
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Review Articles S Kumar, R Moorthy The Journal of Laryngology & Otology,FirstView Article(s), 5 pages Abstract from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1SB2AYR via IFTTT
An In Vitro Study of Condylar Displacement Caused by Interocclusal Records: Influence of Recording Material, Storage Time, and Recording Technique
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Purpose To evaluate the condylar displacement after mounting working casts using different interocclusal recording materials and to analyze the influence of the storage time and the recording technique on the displacement caused by the interocclusal record. Materials and Methods Eight interocclusal records were made in each of the following groups: G1: Aluwax (aluminum wax), […]
Cleaning Methods for Zirconia Following Salivary Contamination
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Purpose To determine the best method of cleaning saliva-contaminated zirconia in preparation for resin bonding. Material and Methods Flat blocks of zirconia were particle abraded with aluminum oxide and divided into eight groups (n = 10). Groups 1 to 4 were first treated with one coat of an MDP primer (Z-prime Plus) and groups […]
In Vitro Analysis of Surface Roughness of Acrylic Resin Exposed to the Combined Hygiene Method of Brushing and Immersion in Ricinus communis and Sodium Hypochlorite
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Purpose To evaluate a solution based on Ricinus communis (Castor oil) for denture cleansing, comparing it to sodium hypochlorite (NaOCl) for the surface roughness of heat-polymerized acrylic resin. Materials and Methods Forty polished and unpolished resin specimens (90 × 30 × 4 mm) were evaluated before and after their exposure to protocol hygiene: brushing […]
Pathology of Fungal Rhinosinusitis: A Review
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Fungal rhinosinusitis (FRS) comprises a spectrum of disease processes that vary in clinical presentation, histologic appearances, and biological significance. FRS can be acute or chronic and is most commonly classified as non-invasive or invasive based on whether fungi have invaded into tissue. This manuscript will review the pathologic classification of FRS. from #ORL-AlexandrosSfakianakis via […]
Newly Described Tumor Entities in Sinonasal Tract Pathology
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Surgical pathology of the sinonasal tract (nasal cavity and paranasal sinuses) is extremely challenging due in part to the tremendous diversity of tumor types that may arise in this region. Compounding the difficulty, a number of new sinonasal tumor entities have been recently described, and pathologists may not yet be familiar with these neoplasms. […]
Endonasal Endoscopic Surgery in the Management of Sinonasal and Anterior Skull Base Malignancies
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Sinonasal malignancies represent a rare subset of tumors with a wide variety of histopathologic diagnoses and overall poor prognosis. These tumors tend to have an insidious onset with non-specific symptoms which often leads to delayed diagnosis and advanced local disease at presentation. The principal goal of surgery is to obtain a negative margin resection. […]
An Update on Sinonasal Round Cell Undifferentiated Tumors
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract The sinonasal cavities host a wide variety of undifferentiated malignancies with round cell morphology, including neoplasms of epithelial, mesenchymal, neuroectodermal, and hematolymphoid lineage. The differential diagnosis may be difficult, especially in small biopsy material, due to overlapping morphology, but their correct classification is clinically relevant. The aim of this review is to provide practical […]
Sinonasal Adenocarcinoma: Update on Classification, Immunophenotype and Molecular Features
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Adenocarcinomas of the sinonasal tract may originate from respiratory surface epithelium or the underlying seromucinous glands. These malignancies are divided into salivary-type adenocarcinomas and non-salivary-type adenocarcinomas. The latter are further divided into intestinal-type and nonintestinal-type adenocarcinomas. This review provides an update on tumor classification, differential diagnostic considerations and molecular features, as well as new […]
Hematolymphoid Lesions of the Sinonasal Tract
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Hematolymphoid neoplasms of the sinonasal tract are rare and the majority represents non-Hodgkin lymphomas. This review will focus on morphologic, immunophenotypic, and genetic characteristics of the most common types of non-Hodgkin lymphoma, namely diffuse large B cell lymphoma and extranodal natural killer/T-cell lymphoma, nasal type, but also include the discussion of less frequent other […]
Non-infectious Inflammatory Lesions of the Sinonasal Tract
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract This review covers the histopathology and pathogenesis of non-infectious inflammatory diseases of the sinonasal tract, in particular, sarcoidosis, granulomatous vasculitides Wegener, Churg–Strauss), relapsing polychondritis, eosinophilic angiocentric fibrosis, chronic rhinosinusitis and nasal perforations. Molecular associations and mechanisms are emphasised to assist pathologists to put their observations into the context of clinical, genetic and environmental influences […]
Tissue-specific regulation of flowering by photoreceptors
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
Abstract Plants use various kinds of environmental signals to adjust the timing of the transition from the vegetative to reproductive phase (flowering). Since flowering at the appropriate time is crucial for plant reproductive strategy, several kinds of photoreceptors are deployed to sense environmental light conditions. In this review, we will update our current understanding of light signaling pathways in flowering regulation, especially, in which tissue do photoreceptors regulate flowering in response to light quality and photoperiod. Since light signaling is also integrated in... περισσότερα »
Mechanisms of sodium channel clustering and its influence on axonal impulse conduction
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
Abstract The efficient propagation of action potentials along nervous fibers is necessary for animals to interact with the environment with timeliness and precision. Myelination of axons is an essential step to ensure fast action potential propagation by saltatory conduction, a process that requires highly concentrated voltage-gated sodium channels at the nodes of Ranvier. Recent studies suggest that the clustering of sodium channels can influence axonal impulse conduction in both myelinated and unmyelinated fibers, which could have major implications in disease, particularly demye... περισσότερα »
Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
Abstract Mitochondria are an essential source of ATP for cellular function, but when damaged, mitochondria generate a plethora of stress signals, which lead to cellular dysfunction and eventually programmed cell death. Thus, a major component of maintaining cellular homeostasis is the recognition and removal of dysfunctional mitochondria through autophagy-mediated degradation, i.e., mitophagy. Mitophagy further constitutes a developmental program, and undergoes a high degree of crosstalk with apoptosis. Reduced mitochondrial quality control is linked to disease pathogenesis, sugges...περισσότερα »
A role for retromer in hepatitis C virus replication
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
Abstract Hepatitis C virus (HCV) has infected over 170 million people worldwide. Phosphatidylinositol 4-phosphate (PI4P) is the organelle-specific phosphoinositide enriched at sites of HCV replication. Whether retromer, a PI4P-related host transport machinery, unloads its cargo at HCV replication sites remains inconclusive. We sought to characterize the role of retromer in HCV replication. Here, we demonstrated the interaction between retromer subunit Vps35 and HCV NS5A protein by immunoprecipitation and GST pulldown. Vps35 colocalized with NS5A and PI4P in both OR6 replicon and JF... περισσότερα »
Comparative analysis of zebrafish bone morphogenetic proteins 2, 4 and 16: molecular and evolutionary perspectives
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
Abstract BMP2, BMP4 and BMP16 form a subfamily of bone morphogenetic proteins acting as pleiotropic growth factors during development and as bone inducers during osteogenesis. BMP16 is the most recent member of this subfamily and basic data regarding protein structure and function, and spatio-temporal gene expression is still scarce. In this work, insights on BMP16 were provided through the comparative analysis of structural and functional data for zebrafish BMP2a, BMP2b, BMP4 and BMP16 genes and proteins, determined from three-dimensional models, patterns of gene expression during... περισσότερα »
microRNAs as neuroregulators, biomarkers and therapeutic agents in neurodegenerative diseases
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
Abstract The last decade has experienced the emergence of microRNAs as a key molecular tool for the diagnosis and prognosis of human diseases. Although the focus has mostly been on cancer, neurodegenerative diseases present an exciting, yet less explored, platform for microRNA research. Several studies have highlighted the significance of microRNAs in neurogenesis and neurodegeneration, and pre-clinical studies have shown the potential of microRNAs as biomarkers. Despite this, no bona fide microRNAs have been identified as true diagnostic or prognostic biomarkers for neurodegenera...περισσότερα »
Brain glucose metabolism during hypoglycemia in type 1 diabetes: insights from functional and metabolic neuroimaging studies
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
Abstract Hypoglycemia is the most frequent complication of insulin therapy in patients with type 1 diabetes. Since the brain is reliant on circulating glucose as its main source of energy, hypoglycemia poses a threat for normal brain function. Paradoxically, although hypoglycemia commonly induces immediate decline in cognitive function, long-lasting changes in brain structure and cognitive function are uncommon in patients with type 1 diabetes. In fact, recurrent hypoglycemia initiates a process of habituation that suppresses hormonal responses to and impairs awareness of subseque...περισσότερα »
Comparison of the protective effects of intratympanic dexamethasone and methylprednisolone against cisplatin-induced ototoxicity
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Research Articles H E Özel, F Özdoğan, S G Gürgen, E Esen, S Genç, A Selçuk The Journal of Laryngology & Otology,FirstView Article(s), 10 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SB2AYZ via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
New oral anticoagulants – a guide for ENT surgeons
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Review Articles S Kumar, R Moorthy The Journal of Laryngology & Otology,FirstView Article(s), 5 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SB2AYR via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Issue Information
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1JV6ivc via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Erratum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1POKLAv via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Daily microhabitat shifting of solitarious-phase Desert locust adults: implications for meaningful population monitoring
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The Desert locust Schistocerca gregaria is a major world pest that causes substantial agricultural and economic damage. Effective pest control relies on effective monitoring, which requires knowledge of locust microhabitat selection. Yet little is known about microhabitat selection of solitarious adult locusts in the field. We conducted field surveys to investigate fine-scale diel temporal and […]
Discovery and expression of 3 siglecs-like in Oreochromis niloticus neutrophil, and their interaction with group B streptococcal sialylated capsular polysaccharides
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 1 February 2016 Source:Molecular Immunology Author(s): Junjian Dong, Yuanzheng Wei, Xing Ye, Chengfei Sun, Yuanyuan Tian, Maixin Lu, Juanjuan Du, Zhihang Chen Sialic acid – binding immunoglobulin – like lectins (Siglecs) are members of the largest superfamily of immune receptors; they recognize sialic acid and are mainly expressed in immune cells. […]
Is dextrose prolotherapy superior to placebo for the treatment of temporomandibular joint hypermobility? A randomized clinical trial
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
A randomized clinical trial involving adult patients with bilateral temporomandibular joint (TMJ) hypermobility referred for treatment was implemented. The sample comprised 30 consecutive patients, who were divided randomly into two groups. The TMJ hypermobility was treated with either saline (placebo group) or dextrose injections (study group). The solution was injected into five different TMJ areas […]
Incidence and recovery of neurosensory disturbances after bilateral sagittal split osteotomy in different age groups: a retrospective study of 263 patients
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
This study aimed to investigate the incidence of neurosensory disturbance (NSD) after bilateral sagittal split osteotomy (BSSO) in different age groups and to assess the probability of sensory recovery in patients aged 30 years. Hypoaesthesia of the lower lip was assessed subjectively and objectively immediately after BSSO and at 1 week and 1, 6, and […]
Application of buccal fat pad-derived stem cells in combination with autogenous iliac bone graft in the treatment of maxillomandibular atrophy: a preliminary human study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
This study assessed the efficacy of buccal fat pad-derived stem cells (BFPSCs) with iliac bone block grafting for the treatment of extensive human alveolar ridge defects. Eight patients with extensive jaw atrophy were selected for this study. The jaws were reconstructed with non-vascularized anterior iliac crest bone blocks. Gaps between the blocks were filled with […]
Searching the perfect ultrasonic classification in assessing carotid artery stenosis: comparison and remarks upon the existing ultrasound criteria
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Doppler ultrasound scanning is the first line investigation for quantifying the internal carotid artery stenosis. Nevertheless, the lack of internationally accepted ultrasound criteria for describing the degree of stenosis has contributed to the different and confusing measurements ranges. The use of two different angiographic methods, the North American Symptomatic Carotid Endoarterectomy Study and the […]
Cleaning Methods for Zirconia Following Salivary Contamination
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Abstract Purpose To determine the best method of cleaning saliva-contaminated zirconia in preparation for resin bonding. Material and Methods Flat blocks of zirconia were particle abraded with aluminum oxide and divided into eight groups (n = 10). Groups 1 to 4 were first treated with one coat of an MDP primer (Z-prime Plus) and groups 5 to 8 were left untreated. A thin coat of fresh whole saliva was painted on all specimens (except the control, group 1) and left in contact for 3 minutes. The specimens were then cleaned by rinsing with water for 20 seconds (groups 2 and 5), or c... περισσότερα »
In Vitro Analysis of Surface Roughness of Acrylic Resin Exposed to the Combined Hygiene Method of Brushing and Immersion in Ricinus communis and Sodium Hypochlorite
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Abstract Purpose To evaluate a solution based on *Ricinus communis* (Castor oil) for denture cleansing, comparing it to sodium hypochlorite (NaOCl) for the surface roughness of heat-polymerized acrylic resin. Materials and Methods Forty polished and unpolished resin specimens (90 × 30 × 4 mm) were evaluated before and after their exposure to protocol hygiene: brushing the specimens with a specific denture brush and mild soap for 3 minutes, three times a day, and immersing them in hygiene solutions (0.25% NaOCl—S1 and 0.5% NaOCl—S2; 10% *R. communis—*S3; saline—S4: control) for 20... περισσότερα »
ICRP 129 and Cone Beam Computed Tomography
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
[image: alertIcon.gif] Publication date: Available online 2 February 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): James R. Geist from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1JV6TwZ via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Is dextrose prolotherapy superior to placebo for the treatment of temporomandibular joint hypermobility? A randomized clinical trial
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Publication date: Available online 2 February 2016 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): S. Cömert Kiliç, M. Güngörmüş A randomized clinical trial involving adult patients with bilateral temporomandibular joint (TMJ) hypermobility referred for treatment was implemented. The sample comprised 30 consecutive patients, who were divided randomly into two groups. The TMJ hypermobility was treated with either saline (placebo group) or dextrose injections (study group). The solution was injected into five different TMJ areas in three sessions at monthly ... περισσότερα »
Discovery and expression of 3 siglecs-like in Oreochromis niloticus neutrophil, and their interaction with group B streptococcal sialylated capsular polysaccharides
Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 1 ώρα
Publication date: Available online 1 February 2016 *Source:*Molecular Immunology Author(s): Junjian Dong, Yuanzheng Wei, Xing Ye, Chengfei Sun, Yuanyuan Tian, Maixin Lu, Juanjuan Du, Zhihang Chen Sialic acid – binding immunoglobulin – like lectins (Siglecs) are members of the largest superfamily of immune receptors; they recognize sialic acid and are mainly expressed in immune cells. Studies on mammals indicate that Streptococcus agalactiae (GBS) evade immune reactions by interacting with the host immune cells via the sialic acid of sialylated capsular polysaccharides. However, it i... περισσότερα »
An In Vitro Study of Condylar Displacement Caused by Interocclusal Records: Influence of Recording Material, Storage Time, and Recording Technique
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Purpose To evaluate the condylar displacement after mounting working casts using different interocclusal recording materials and to analyze the influence of the storage time and the recording technique on the displacement caused by the interocclusal record. Materials and Methods Eight interocclusal records were made in each of the following groups: G1: Aluwax (aluminum wax), […]
Cleaning Methods for Zirconia Following Salivary Contamination
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Purpose To determine the best method of cleaning saliva-contaminated zirconia in preparation for resin bonding. Material and Methods Flat blocks of zirconia were particle abraded with aluminum oxide and divided into eight groups (n = 10). Groups 1 to 4 were first treated with one coat of an MDP primer (Z-prime Plus) and groups […]
In Vitro Analysis of Surface Roughness of Acrylic Resin Exposed to the Combined Hygiene Method of Brushing and Immersion in Ricinus communis and Sodium Hypochlorite
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Purpose To evaluate a solution based on Ricinus communis (Castor oil) for denture cleansing, comparing it to sodium hypochlorite (NaOCl) for the surface roughness of heat-polymerized acrylic resin. Materials and Methods Forty polished and unpolished resin specimens (90 × 30 × 4 mm) were evaluated before and after their exposure to protocol hygiene: brushing […]
Pathology of Fungal Rhinosinusitis: A Review
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Fungal rhinosinusitis (FRS) comprises a spectrum of disease processes that vary in clinical presentation, histologic appearances, and biological significance. FRS can be acute or chronic and is most commonly classified as non-invasive or invasive based on whether fungi have invaded into tissue. This manuscript will review the pathologic classification of FRS. from #ORL-Sfakianakis via […]
Newly Described Tumor Entities in Sinonasal Tract Pathology
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Surgical pathology of the sinonasal tract (nasal cavity and paranasal sinuses) is extremely challenging due in part to the tremendous diversity of tumor types that may arise in this region. Compounding the difficulty, a number of new sinonasal tumor entities have been recently described, and pathologists may not yet be familiar with these neoplasms. […]
Endonasal Endoscopic Surgery in the Management of Sinonasal and Anterior Skull Base Malignancies
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Sinonasal malignancies represent a rare subset of tumors with a wide variety of histopathologic diagnoses and overall poor prognosis. These tumors tend to have an insidious onset with non-specific symptoms which often leads to delayed diagnosis and advanced local disease at presentation. The principal goal of surgery is to obtain a negative margin resection. […]
An Update on Sinonasal Round Cell Undifferentiated Tumors
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract The sinonasal cavities host a wide variety of undifferentiated malignancies with round cell morphology, including neoplasms of epithelial, mesenchymal, neuroectodermal, and hematolymphoid lineage. The differential diagnosis may be difficult, especially in small biopsy material, due to overlapping morphology, but their correct classification is clinically relevant. The aim of this review is to provide practical […]
Sinonasal Adenocarcinoma: Update on Classification, Immunophenotype and Molecular Features
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Adenocarcinomas of the sinonasal tract may originate from respiratory surface epithelium or the underlying seromucinous glands. These malignancies are divided into salivary-type adenocarcinomas and non-salivary-type adenocarcinomas. The latter are further divided into intestinal-type and nonintestinal-type adenocarcinomas. This review provides an update on tumor classification, differential diagnostic considerations and molecular features, as well as new […]
Hematolymphoid Lesions of the Sinonasal Tract
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Hematolymphoid neoplasms of the sinonasal tract are rare and the majority represents non-Hodgkin lymphomas. This review will focus on morphologic, immunophenotypic, and genetic characteristics of the most common types of non-Hodgkin lymphoma, namely diffuse large B cell lymphoma and extranodal natural killer/T-cell lymphoma, nasal type, but also include the discussion of less frequent other […]
Non-infectious Inflammatory Lesions of the Sinonasal Tract
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract This review covers the histopathology and pathogenesis of non-infectious inflammatory diseases of the sinonasal tract, in particular, sarcoidosis, granulomatous vasculitides Wegener, Churg–Strauss), relapsing polychondritis, eosinophilic angiocentric fibrosis, chronic rhinosinusitis and nasal perforations. Molecular associations and mechanisms are emphasised to assist pathologists to put their observations into the context of clinical, genetic and environmental influences […]
Contextualising primate origins – an ecomorphological framework
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Abstract Ecomorphology – the characterisation of the adaptive relationship between an organism’s morphology and its ecological role – has long been central to theories of the origin and early evolution of the primate order. This is exemplified by two of the most influential theories of primate origins: Matt Cartmill’s Visual Predation Hypothesis, and Bob Sussman’s […]
Pathology in the Medical Profession?
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 2 ώρες
*Pathology in the Medical Profession?* Arch Pathol Lab Med. 2016 Feb 1; Authors: Schrijver I Abstract Context .- In the past decades, physician wellness has diminished in every aspect of professional life. Burnout symptoms in the United States affect 30% to 68% of physicians overall-exceeding the levels of any other professional group. The ramifications of burnout present an underrecognized crisis in the health care system that carries the consequences of personal, professional, institutional, and societal costs. Objective .- To bring to light the elements of current medical pra...περισσότερα »
Contextualising primate origins – an ecomorphological framework
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 2 ώρες
Abstract Ecomorphology – the characterisation of the adaptive relationship between an organism's morphology and its ecological role – has long been central to theories of the origin and early evolution of the primate order. This is exemplified by two of the most influential theories of primate origins: Matt Cartmill's Visual Predation Hypothesis, and Bob Sussman's Angiosperm Co-Evolution Hypothesis. However, the study of primate origins is constrained by the absence of data directly documenting the events under investigation, and has to rely instead on a fragmentary fossil record a... περισσότερα »
