Compared with an approach of an NG tube as required, the use of a prophylactic gastrostomy was associated with inferior long term patient-reported long term swallow outcomes.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Impact of prophylactic gastrostomy or reactive NG tube upon patient-reported long term swallow function following chemoradiotherapy for oropharyngeal carcinoma: A matched pair analysis via ScienceDirect Search: ESOPHAGEAL CANCER Publication date: August 2016Source:Oral Oncology, Volume 59Author(s): Brinda Sethugavalar, Mark T. Teo, Catriona Buchan, Ekin Ermiş, Gillian F. Williams, Mehmet Sen, Robin J.D. PrestwichObjectivesThe purpose of this matched […]
Abnormality of Auditory Mismatch Negativity in Depression
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
and Its Dependence on Stimulus Intensity.: Clin EEG Neurosci. 2016;47(2):105-12 Authors: Restuccia D, Vollono C, Scaloni L, Buccelletti F, Camardese G Abstract Mismatch negativity (MMN) is thought to reveal several abnormalities of cognitive functioning. Although depression often affects cognitive functioning, previous studies concerning MMN in depressed patients provided conflicting results. In recent reports, it has […]
Impaired Facilitatory Mechanisms of Auditory Attention After Damage of the Lateral Prefrontal Cortex.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Authors: Bidet-Caulet A, Buchanan KG, Viswanath H, Black J, Scabini D, Bonnet-Brilhault F, Knight RT Abstract There is growing evidence that auditory selective attention operates via distinct facilitatory and inhibitory mechanisms enabling selective enhancement and suppression of sound processing, respectively. The lateral prefrontal cortex (LPFC) plays a crucial role in the top-down control of […]
Listen to Yourself: The Medial Prefrontal Cortex Modulates Auditory Alpha Power During Speech Preparation.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Authors: Müller N, Leske S, Hartmann T, Szebényi S, Weisz N Abstract How do we process stimuli that stem from the external world and stimuli that are self-generated? In the case of voice perception it has been shown that evoked activity elicited by self-generated sounds is suppressed compared with the same sounds played-back externally. We […]
Paraneoplastic Opsoclonus associated with Squamous Cell carcinoma of the Tongue
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Paraneoplastic Opsoclonus associated with Squamous Cell carcinoma of the Tongue via Clinical Neurology and Neurosurgery Source:Clinical Neurology and NeurosurgeryAuthor(s): DonRaphael Wynn, Joseph Merriman, Ami B. Patel, Ying J. Hitchcock, Ignacio Garrido-Laguna, David Renner, Stacey L. Clardy Highlights • In the setting of opsoclonus it is essential to diligently screen for malignancy. • Opsoclonus may be the […]
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors : Acinar Cell Carcinoma Adrenal Cortex Carcinoma Adrenal Gland Pheochromocytoma Anal Canal Neuroendocrine Carcinoma Anal Canal Undifferentiated Carcinoma Appendix Mucinous Adenocarcinoma Bladder Adenocarcinoma Bronchioloalveolar Carcinoma Cervical Adenocarcinoma Cervical Squamous Cell Carcinoma, Not Otherwise Specified Cholangiocarcinoma Chordoma Colorectal Squamous Cell Carcinoma Endometrial Adenocarcinoma Endometrioid Adenocarcinoma Esophageal Neuroendocrine Carcinoma Esophageal Undifferentiated Carcinoma Extrahepatic Bile Duct Carcinoma Fallopian Tube Adenocarcinoma Fibromyxoid Tumor Gastric Neuroendocrine Carcinoma Gastric Squamous Cell Carcinoma Giant Cell Carcinoma Intestinal Neuroendocrine Carcinoma Intrahepatic Cholangiocarcinoma Lung Carcinoid Tumor Lung Sarcomatoid Carcinoma Major Salivary Gland Carcinoma Malignant Odontogenic Neoplasm Malignant Peripheral Nerve Sheath Tumor Malignant Skin Neoplasm Malignant Testicular Sex Cord-Stromal Tumor Metastatic Malignant Neoplasm of Unknown Primary Origin Mixed Mesodermal (Mullerian) Tumor Mucinous Adenocarcinoma Mucinous Cystadenocarcinoma Nasal Cavity Adenocarcinoma Nasal Cavity Carcinoma Nasopharyngeal Carcinoma Nasopharyngeal Papillary Adenocarcinoma Nasopharyngeal Undifferentiated Carcinoma Oral Cavity Carcinoma Oropharyngeal Undifferentiated Carcinoma Ovarian Adenocarcinoma Ovarian Germ Cell Tumor Ovarian Mucinous Adenocarcinoma Ovarian Squamous Cell Carcinoma Pancreatic Acinar Cell Carcinoma Pancreatic Neuroendocrine Carcinoma Paraganglioma Paranasal Sinus Adenocarcinoma Paranasal Sinus Carcinoma Parathyroid Gland Carcinoma Pituitary Gland Carcinoma Placental Choriocarcinoma Placental-Site Gestational Trophoblastic Tumor Primary Peritoneal High Grade Serous Adenocarcinoma Pseudomyxoma Peritonei Scrotal Squamous Cell Carcinoma Seminal Vesicle Adenocarcinoma Seminoma Serous Cystadenocarcinoma Small Intestinal Adenocarcinoma Small Intestinal Squamous Cell Carcinoma Spindle Cell Neoplasm Squamous Cell Carcinoma of the Penis Teratoma With Malignant Transformation Testicular Non-Seminomatous Germ Cell Tumor Thyroid Gland Carcinoma Tracheal Carcinoma Transitional Cell Carcinoma Undifferentiated Gastric Carcinoma Ureter Adenocarcinoma Ureter Squamous Cell Carcinoma Urethral Adenocarcinoma Urethral Squamous Cell Carcinoma Vaginal Adenocarcinoma Vaginal Squamous Cell Carcinoma, Not Otherwise Specified Vulvar Adenocarcinoma Vulvar Squamous Cell Carcinoma
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors: This clinical trial studies nivolumab and ipilimumab in treating patients with rare tumors. Monoclonal antibodies, such as nivolumab and ipilimumab, may interfere with the ability of tumor cells to grow and spread. Condition Intervention Acinar Cell CarcinomaAdrenal Cortex CarcinomaAdrenal Gland PheochromocytomaAnal Canal Neuroendocrine CarcinomaAnal Canal Undifferentiated […]
A Dose Reduction Immunobridging and Safety Study of Two HPV Vaccines
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
in Tanzanian Girls: Condition: Human Papilloma Virus Interventions: Drug: bivalent HPV vaccine; Drug: nonavalent HPV vaccine Sponsors: London School of Hygiene and Tropical Medicine; University of York; Catalan Institute of Oncology; National Cancer Institute at Frederick; Karolinska Institutet; Technische Universität Berlin; Tanzanian National Institute for Medical Research; University of Glasgow Cervical cancer is the most common cancer in women aged 15-44 years in East Africa, and mortality rates are very high. HPV vaccines are most effective if given […]
Sagittal plane alignment of the foot
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Shod wear and foot alignment in clinical gait analysis via Gait & Posture Publication date: September 2016Source:Gait & Posture, Volume 49Author(s): Melissa Gar Yee Louey, Morgan SangeuxSagittal plane alignment of the foot presents challenges when the subject wears shoes during gait analysis. Typically, visual alignment is performed by positioning two markers, the heel and toe markers, […]
Deficits in medio-lateral balance control
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
and the implications for falls in individuals with multiple sclerosis via Gait & Posture Publication date: September 2016Source:Gait & Posture, Volume 49Author(s): S. Morrison, C.A. Rynders, J.J. SosnoffA major health concern faced by individuals with Multiple Sclerosis (MS) is the heightened risk of falling. Reasons for this increased risk can often be traced back to declines […]
Oral mizoribine in refractory ocular manifestation of mucosal pemphigus vulgaris
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 λεπτό
Successful treatment with oral mizoribine in refractory ocular manifestation of mucosal pemphigus vulgaris: A unique response to different immunosuppressive drugs: Abstract Pemphigus vulgaris (PV) is an acquired autoimmune disease in which the disease characteristic antibodies are directed against the desmosomal transmembrane glycoprotein, desmoglein 3 (Dsg 3), resulting in flaccid blisters and erosions of skin and […]
Evolución hacia nuevas estrategias terapéuticas | Estudios por imágenes de la aterosclerosis coronaria
Los adelantos en los estudios por imágenes pueden identificar a los pacientes "vulnerables", que tienen el mayor riesgo de infarto del miocardio, a fin de que puedan recibir tratamientos intensivos para prevenir futuros episodios. from Uncategorized via xlomafota13 on Inoreader http://ift.tt/2a5emL4 via IFTTT
PGC-1α Mediated Peripheral Nerve Protection of Tongxinluo in STZ-Induced Diabetic Rats
Aim. To investigate the effect of Tongxinluo (Txl), a Chinese herbal compound, on diabetic peripheral neuropathy (DPN). Methods and Results. Diabetic rat model was established by peritoneal injection of streptozotocin (STZ). Txl ultrafine powder treatment for 16 weeks from the baseline significantly reversed the impairment of motor nerve conductive velocity (MNCV), mechanical hyperalgesia, and nerve structure. We further proved that Tongxinluo upregulates PGC-1α and its downstream factors including COX IV and SOD, which were involved in mitochondrial biogenesis. Conclusion. Our st... περισσότερα »
PGC-1α Mediated Peripheral Nerve Protection of Tongxinluo in STZ-Induced Diabetic Rats
Aim. To investigate the effect of Tongxinluo (Txl), a Chinese herbal compound, on diabetic peripheral neuropathy (DPN). Methods and Results. Diabetic rat model was established by peritoneal injection of streptozotocin (STZ). Txl ultrafine powder treatment for 16 weeks from the baseline significantly reversed the impairment of motor nerve conductive velocity (MNCV), mechanical hyperalgesia, and nerve structure. We further proved that Tongxinluo upregulates PGC-1α and its downstream factors including COX IV and SOD, which were involved in mitochondrial biogenesis. Conclusion. Our st... περισσότερα »
Endovascular Therapy for Large Vessel Vasculopathy in HIV-infected Patients
Publication date: Available online 16 July 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): B. Pillay, P.K. Ramdial, D.P. Naidoo, B. Sartorius, D. Singh ObjectivesTo evaluate outcomes after endovascular treatment of patients with aneurysmal or occlusive vasculopathy in HIV-infected patients.MethodsRetrospective analysis of a prospective database of treatment outcomes in patients with HIV related vasculopathies between April 2005 and September 2015.ResultsSixty HIV patients presented with post-traumatic pseudoaneurysm formation (n = 7), aneurysmal disease... περισσότερα »
Increased Bone Resorption: A Possible Pathophysiological Link Between Hypovitaminosis D and Peripheral Arterial Disease
Publication date: Available online 16 July 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): L. Pasqualini, S. Ministrini, A. Macura, E. Marini, C. Leli, D. Siepi, R. Lombardini, M.N. Kararoudi, A.M. Scarponi, G. Schillaci, M. Pirro, E. Mannarino Objective/BackgroundVitamin D deficiency has been associated with the prevalence and severity of peripheral arterial disease (PAD); nevertheless, data on bone turnover in patients with PAD is lacking. The present study investigates a possible relationship between the markers of bone turnover and the presence and... περισσότερα »
Advising Sinusitis Patients to Use Nasal Irrigation May Help Improve Symptoms (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH Patients with chronic or recurrent sinusitis who were advised to use nasal irrigation had a modest reduction in symptoms, according … from Uncategorized via xlomafota13 on Inoreader http://ift.tt/2am48Fj via IFTTT
The Renal Cell Carcinomas
Alexandros G. SfakianakisστοSquamous cell carcinoma (SCC) - Cancer - MelanomaΠριν από 9 δευτερόλεπτα
The renal cell carcinomas (RCC), clear cell, papillary, and chromophobe, have recently undergone an unmatched genomic characterization by The Cancer Genome Atlas. This analysis has revealed new insights into each of these malignancies and underscores the unique biology of clear cell, papillary, and chromophobe RCC. Themes that have emerged include distinct mechanisms of metabolic dysregulation and common mutations in chromatin modifier genes. Importantly, the papillary RCC classification encompasses a heterogeneous group of diseases, each with highly distinct genetic and molecular... περισσότερα »
ANRIL Deregulation in Breast Cancer
Alexandros G. SfakianakisστοSquamous cell carcinoma (SCC) - Cancer - MelanomaΠριν από 9 δευτερόλεπτα
ANRIL, a long noncoding RNA (lncRNA), has recently been reported to have a direct role in recruiting polycomb repressive complexes PRC2 and PRC1 to regulate the expression of the p15/CDKN2B-p16/CDKN2A-p14/ARF gene cluster. Expression analysis of *ANRIL, EZH2, SUZ12, EED, JARID2, CBX7, BMI1, p16, p15*, and *p14/ARF* genes was evaluated in a large cohort of invasive breast carcinomas (IBC, *n* = 456) by qRT-PCR and immunohistochemistry (IHC) was performed on CBX7, EZH2, p14, p15, p16, H3K27me3, and H3K27ac. We observed significant overexpression in IBCs of *ANRIL* (19.7%) and *EZH2* ... περισσότερα »
Selected Articles from This Issue
Alexandros G. SfakianakisστοSquamous cell carcinoma (SCC) - Cancer - MelanomaΠριν από 9 δευτερόλεπτα
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HuR Mediates TRAIL Resistance
Alexandros G. SfakianakisστοSquamous cell carcinoma (SCC) - Cancer - MelanomaΠριν από 9 δευτερόλεπτα
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal cancers, in part, due to resistance to both conventional and targeted therapeutics. TRAIL directly induces apoptosis through engagement of cell surface Death Receptors (DR4 and DR5), and has been explored as a molecular target for cancer treatment. Clinical trials with recombinant TRAIL and DR-targeting agents, however, have failed to show overall positive outcomes. Herein, we identify a novel TRAIL resistance mechanism governed by Hu antigen R (HuR, ELAV1), a stress-response protein abundant and functional in PDA cel... περισσότερα »
DNA Repair Inhibition by Oxidative Stress
Alexandros G. SfakianakisστοSquamous cell carcinoma (SCC) - Cancer - MelanomaΠριν από 10 δευτερόλεπτα
The relationship between sun exposure and nonmelanoma skin cancer risk is well established. Solar UV (wavelength 280–400 nm) is firmly implicated in skin cancer development. Nucleotide excision repair (NER) protects against cancer by removing potentially mutagenic DNA lesions induced by UVB (280–320 nm). How the 20-fold more abundant UVA (320–400 nm) component of solar UV radiation increases skin cancer risk is not understood. Here it is demonstrated that the contribution of UVA to the effect of UV radiation on cultured human cells is largely independent of its ability to damage DN... περισσότερα »
HNRNP E1 Posttranscriptionally Regulates CDC27 Expression
Alexandros G. SfakianakisστοSquamous cell carcinoma (SCC) - Cancer - MelanomaΠριν από 10 δευτερόλεπτα
CDC27 is a core component of the anaphase-promoting complex/cyclosome (APC/C), a multisubunit E3 ubiquitin ligase, whose oscillatory activity is responsible for the metaphase-to-anaphase transition and mitotic exit. Here, in normal murine mammary gland epithelial cells (NMuMG), CDC27 expression is controlled posttranscriptionally through the RNA binding protein poly(rC) binding protein 1 (PCBP1)/heterogeneous nuclear ribonucleoprotein E1 (HNRNP E1). shRNA-mediated knockdown of HNRNP E1 abrogates translational silencing of the *Cdc27* transcript, resulting in constitutive expressio... περισσότερα »
The Effect of Adipose Stem Cells on Breast Cancer
Alexandros G. SfakianakisστοSquamous cell carcinoma (SCC) - Cancer - MelanomaΠριν από 10 δευτερόλεπτα
Adipose-derived stem cells (ASC) have received considerable attention in oncology because of the known direct link between obesity and cancer as well as the use of ASCs in reconstructive surgery after tumor ablation. Previous studies have documented how cancer cells commandeer ASCs to support their survival by altering extracellular matrix composition and stiffness, migration, and metastasis. This study focused on delineating the effects of ASCs and adipocytes on the self-renewal of stem/progenitor cells and hierarchy of breast epithelial cells. The immortalized breast epithelial ... περισσότερα »
Cancers, Vol. 8, Pages 69: Wnt Lipidation and Modifiers in Intestinal Carcinogenesis and Cancer
Alexandros G. SfakianakisστοSquamous cell carcinoma (SCC) - Cancer - MelanomaΠριν από 10 δευτερόλεπτα
The wingless (Wnt) signaling is suggested as a fundamental hierarchical pathway in regulation of proliferation and differentiation of cells. The Wnt ligands are small proteins of about 40 kDa essentially for regulation and initiation of the Wnt activity. They are secreted proteins requiring acylation for activity in the Wnt signaling cascade and for functional interactivity with transmembrane proteins. Dual lipidation is important for posttranslational activation of the overwhelming number of Wnt proteins and is probably involved in their spatial distribution. The intestinal mucosa... περισσότερα »
American Board of Dermatology Examination Dates
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Is oral cancer incidence among patients with oral lichen planus/oral lichenoid lesions underestimated?
Background Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are considered potentially malignant disorders with a cancer incidence of around 1% of cases, although this estimation is controversial. The aim of this study was to analyze the cancer incidence in a case series of patients with OLP and OLL and to explore clinicopathological aspects… Continue reading Is oral cancer incidence among patients with oral lichen planus/oral lichenoid lesions underestimated?
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors : Acinar Cell Carcinoma Adrenal Cortex Carcinoma Adrenal Gland Pheochromocytoma Anal Canal Neuroendocrine Carcinoma Anal Canal Undifferentiated Carcinoma Appendix Mucinous Adenocarcinoma Bladder Adenocarcinoma Bronchioloalveolar Carcinoma Cervical Adenocarcinoma Cervical Squamous Cell Carcinoma, Not Otherwise Specified Cholangiocarcinoma Chordoma Colorectal Squamous Cell Carcinoma Endometrial Adenocarcinoma Endometrioid Adenocarcinoma
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors: This clinical trial studies nivolumab and ipilimumab in treating patients with rare tumors. Monoclonal antibodies, such as nivolumab and ipilimumab, may interfere with the ability of tumor cells to grow and spread. Condition Intervention Acinar Cell Carcinoma Adrenal Cortex Carcinoma Adrenal Gland Pheochromocytoma Anal Canal Neuroendocrine… Continue reading Nivolumab and Ipilimumab in Treating Patients With Rare Tumors : Acinar Cell Carcinoma Adrenal Cortex Carcinoma Adrenal Gland Pheochromocytoma Anal Canal Neuroendocr... περισσότερα »
Lichen striatus with syringotropism and hyperplasia of eccrine gland cells: A rare phenomenon that should not be confused with syringotropic mycosis fungoides
Abstract Background Syringotropism is characterized by lymphocyte infiltration in the eccrine gland and is usually associated with various degrees of hyperplasia of eccrine gland cells. This phenomenon has been reported in rare cases of mycosis fungoides, which are also called as syringotropic mycosis fungoides. Methods We studied 7 cases of lichen striatus associated with syringotropism… Continue reading Lichen striatus with syringotropism and hyperplasia of eccrine gland cells: A rare phenomenon that should not be confused with syringotropic mycosis fungoides
Collaboration of cancer-associated fibroblasts and tumour-associated macrophages for neuroblastoma development
Abstract Neuroblastoma is the most common extracranial solid tumour in children and is histologically classified by its Schwannian stromal cells. Although having fewer Schwannian stromal cells is generally associated with more aggressive phenotypes, the exact roles of other stromal cells (mainly macrophages and fibroblasts) are unclear. Here we examined 41 cases of neuroblastoma using immunohistochemistry… Continue reading Collaboration of cancer-associated fibroblasts and tumour-associated macrophages for neuroblastoma development
Fibroblast Growth Factor-1 attenuates TGF-β1-induced lung fibrosis
Abstract Idiopathic pulmonary fibrosis (IPF) is characterized by progressive fibroblast and myofibroblast proliferation, and extensive deposition of extracellular matrix (ECM). Fibroblast Growth Factor-1 (FGF-1) belongs to the FGF family and has been shown to inhibit fibroblast collagen production and differentiation into myofibroblast, and revert epithelial-mesenchymal transition by inhibiting TGF-β1 signalling pathways. However, the precise role… Continue reading Fibroblast Growth Factor-1 attenuates TGF-β1-induced lung fibrosis
Syphilitic Gumma Arising in Association With Foreign Material
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Issue Information
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Corrigendum
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Diagnostic perplexity of panoramic radiograph
Description A 14-year-old girl presented to the dental clinic with a history of a fall and blow to her upper front teeth. After initial management by the oral surgeon she was referred to the endodontic department for the management of her fractured maxillary incisors. Her medical history was unremarkable. Intraoral examination revealed complicated crown fracture… Continue reading Diagnostic perplexity of panoramic radiograph
Lichen striatus with syringotropism and hyperplasia of eccrine gland cells: A rare phenomenon that should not be confused with syringotropic mycosis fungoides
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Abstract Background Syringotropism is characterized by lymphocyte infiltration in the eccrine gland and is usually associated with various degrees of hyperplasia of eccrine gland cells. This phenomenon has been reported in rare cases of mycosis fungoides, which are also called as syringotropic mycosis fungoides. Methods We studied 7 cases of lichen striatus associated with syringotropism and hyperplasia of eccrine gland cells diagnosed at our dermatology department in the past 5 years. The hematoxylin and eosin stained slides from these cases were analyzed, and immunohistochemica... περισσότερα »
Syphilitic Gumma Arising in Association With Foreign Material
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
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Corrigendum
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
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American Board of Dermatology Examination Dates
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
[image: cover.gif?v=1&s=12b08b877e4e270f0856ca92] from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/29OapYx via IFTTT
Lichen striatus with syringotropism and hyperplasia of eccrine gland cells: A rare phenomenon that should not be confused with syringotropic mycosis fungoides
Abstract Background Syringotropism is characterized by lymphocyte infiltration in the eccrine gland and is usually associated with various degrees of hyperplasia of eccrine gland cells. This phenomenon has been reported in rare cases of mycosis fungoides, which are also called as syringotropic mycosis fungoides. Methods We studied 7 cases of lichen striatus associated with syringotropism and hyperplasia of eccrine gland cells diagnosed at our dermatology department in the past 5 years. The hematoxylin and eosin stained slides from these cases were analyzed, and immunohistochemica... περισσότερα »
Syphilitic Gumma Arising in Association With Foreign Material
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Corrigendum
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American Board of Dermatology Examination Dates
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Is oral cancer incidence among patients with oral lichen planus/oral lichenoid lesions underestimated?
Background Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are considered potentially malignant disorders with a cancer incidence of around 1% of cases, although this estimation is controversial. The aim of this study was to analyze the cancer incidence in a case series of patients with OLP and OLL and to explore clinicopathological aspects that may cause underestimation of the cancer incidence in these diseases. Methods A retrospective study was conducted of 102 patients diagnosed with OLP (*n* = 21, 20.58%) or OLL (*n* = 81) between January 2006 and January 2016. Pat... περισσότερα »
Patient experience and anxiety during and after treatment for an HPV-related oropharyngeal cancer
Publication date: September 2016 *Source:*Oral Oncology, Volume 60 Author(s): Gypsyamber D'Souza, Yuehan Zhang, Samantha Merritt, Dorothy Gold, Hilary A. Robbins, Victoria Buckman, Jennifer Gerber, David W. Eisele, Patrick Ha, Joseph Califano, Carole Fakhry ObjectivesDiagnosis with an HPV-related oropharyngeal cancer includes unique social issues. However, it is unknown how common these psychosocial issues are for patients and whether they continue after treatment.Materials and methodsPatients with pathologically confirmed HPV-positive oropharyngeal cancer (HPV-OPC, n=48) were recru... περισσότερα »
Is oral cancer incidence among patients with oral lichen planus/oral lichenoid lesions underestimated?
Background Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are considered potentially malignant disorders with a cancer incidence of around 1% of cases, although this estimation is controversial. The aim of this study was to analyze the cancer incidence in a case series of patients with OLP and OLL and to explore clinicopathological aspects that may cause underestimation of the cancer incidence in these diseases. Methods A retrospective study was conducted of 102 patients diagnosed with OLP (*n* = 21, 20.58%) or OLL (*n* = 81) between January 2006 and January 2016. Pat... περισσότερα »
Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discussion of the diagnosis and treatment
Publication date: Available online 16 July 2016 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Zoghlami, N. Bon Mardion, F. Callonnec, D. Dehesdin, F. Proust, J.-P. Marie IntroductionSkull base meningoencephaloceles are rare congenital malformations. The two cases of transalar transsphenoidal malformation reported here differ from the classical transsphenoidal meningoencephalocele.Case reportsCase 1 was a three-and-a-half-year-old boy and case 2 was a 36-year-old man. Both cases presented with clinical features of recurrent meningitis. Surgical... περισσότερα »
New images of a calcium-shuttling molecule linked to aggressive cancer
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 23 δευτερόλεπτα
Scientists have captured new images of a calcium-shuttling molecule that has been linked to aggressive cancers. The three-dimensional structure could help researchers develop novel therapies and diagnostic tools for diseases that are caused by a… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/2a40DaH via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxi dation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 23 δευτερόλεπτα
Publication date: August 2016 Source:Free Radical Biology and Medicine, Volume 97 Author(s): Xiaoyu Yang, Yi Xu, Amanda Brooks, Bin Guo, Keith W. Miskimins, Steven Y. Qian Recent research has demonstrated that colon cancer cell proliferation can be suppressed in the cells that overexpress COX-2 via generating 8-hydroxyoctanoic acid (a free radical byproduct) during dihomo-γ-linolenic acid […]
Melatonin prevents adverse myocardial infarction remodeling via Notch1/Mfn2 pathway
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 23 δευτερόλεπτα
Publication date: Available online 5 July 2016 Source:Free Radical Biology and Medicine Author(s): Haifeng Pei, Jin Du, Xiaofeng Song, Lei He, Yufei Zhang, Xiuchuan Li, Chenming Qiu, Yangyang Zhang, Juanni Hou, Juan Feng, Erhe Gao, De Li, Yongjian Yang Mitochondrial dysfunction is linked with myocardial infarction (MI), a disorder in which Notch1 has attracted increasing […]
Peroxynitrite-mediated oxidation of plasma fibronectin
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 23 δευτερόλεπτα
Publication date: Available online 7 July 2016 Source:Free Radical Biology and Medicine Author(s): Georg Degendorfer, Christine Y. Chuang, Hiroaki Kawasaki, Astrid Hammer, Ernst Malle, Fumiyuki Yamakura, Michael J. Davies Fibronectin is a large dimeric glycoprotein present in both human plasma and in basement membranes. The latter are specialized extracellular matrices underlying endothelial cells in the […]
Alpha-synuclein modulates retinal iron homeostasis by facilitating the uptake of transferrin-bound iron: Implications for visual manifestations of Parkinson’s disease
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 23 δευτερόλεπτα
Publication date: August 2016 Source:Free Radical Biology and Medicine, Volume 97 Author(s): Shounak Baksi, Ajai K. Tripathi, Neena Singh Aggregation of α-synuclein (α-syn) in neurons of the substantia nigra is diagnostic of Parkinson’s disease (PD), a neuro-motor disorder with prominent visual symptoms. Here, we demonstrate that α-syn, the principal protein involved in the pathogenesis of […]
Very Low Doses of Ionizing Radiation and Redox Associated Modifiers Affect Survivin-Associated Changes in Radiation Sensitivity
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 23 δευτερόλεπτα
Publication date: Available online 15 July 2016 Source:Free Radical Biology and Medicine Author(s): Richard C. Miller, Jeffrey S. Murley, Alfred W. Rademaker, Gayle E. Woloschak, Jian Jian Li, Ralph R. Weichselbaum, David J. Grdina Exposure of cells to a dose of ionizing radiation as low as 5 mGy can induce changes in radiation sensitivity expressed […]
Mitochondrial impairments contribute to Spinocerebellar ataxia type 1 progression and can be ameliorated by the mitochondria-targeted antioxidant MitoQ
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 23 δευτερόλεπτα
Publication date: Available online 6 July 2016 Source:Free Radical Biology and Medicine Author(s): David M. Stucki, Céline Ruegsegger, Silvio Steiner, Julika Radecke, Michael P. Murphy, Benoît Zuber, Smita Saxena Spinocerebellar ataxia type 1 (SCA1), due to an unstable polyglutamine expansion within the ubiquitously expressed Ataxin-1 protein, leads to the premature degeneration of Purkinje cells (PCs), […]
Photoaging of retinal pigment epithelial melanosomes: The effect of photobleaching on morphology and reactivity of the pigment granules
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 23 δευτερόλεπτα
Publication date: August 2016 Source:Free Radical Biology and Medicine, Volume 97 Author(s): Andrzej Zadlo, Grzegorz Szewczyk, Michal Sarna, Anna Kozinska, Anna Pilat, Patrycja Kaczara, Tadeusz Sarna To elucidate the mechanism of age-related changes in antioxidant and photoprotective properties of human retinal pigment epithelium (RPE) melanosomes, the effect of in vitro photoaging of bovine RPE melanosomes […]
Toxicity, bio-distribution and metabolism of CO-releasing molecules based on cobalt
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 23 δευτερόλεπτα
Publication date: August 2016 Source:Free Radical Biology and Medicine, Volume 97 Author(s): Yaguo Gong, Taofeng Zhang, Meng Li, Na Xi, Yawen Zheng, Quanyi Zhao, Yonglin Chen, Bin Liu CO-releasing molecules (CORMs) containing [Co2(CO)6] moiety show many bioactivities, such as anti-inflammatory and antitumor cell proliferation. However, so far, no one knows their properties in vivo. So, […]
Platinum based radiochemotherapies: free radical mechanisms and radiotherapy sensitizers
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 23 δευτερόλεπτα
Publication date: Available online 12 July 2016 Source:Free Radical Biology and Medicine Author(s): Clifford W. Fong The radiosensitizing ability of Pt drugs can in the first instance be predicted based on the ease that they undergo activation by electron attachment accompanied by structural modification prior to forming Pt-DNA adducts. Unlike cisplatin, carboplatin and nedaplatin, oxaliplatin […]
Biochemical Genetics
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 23 δευτερόλεπτα
Review The Expression of Nuclear Transcription Factor Kappa B (NF-κB) in the Case of Critically Ill Polytrauma Patients with Sepsis and Its Interactions with microRNAs Marius Papurica, Alexandru Florin Rogobete, Dorel Sandesc, Carmen Alina Cradigati, Mirela Sarandan, Dan Ciprian Crisan, Florin George Horhat, Ovidiu Boruga, Raluca Dumache, Kundnani Rajpal Nilima, Razvan Nitu, Horia Stanca & Ovidiu Horea Bedreag » Abstract » Full text HTML » Full text PDF Original Article Genetic Relationships Among Olive (*Olea europaea* L.) Cultivars Native to Turkey Ebru Sakar, Hulya Unver, Me... περισσότερα »
Anaesthesia & Intensive Care Medicine
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 23 δευτερόλεπτα
[image: Anaesthesia & Intensive Care Medicine] Anaesthesia & Intensive Care Medicine Volume 17, Issue 8 , Pages 357-420, August 2016 *Obstetric Anaesthesia* Contents *Pages OFC* Editorial Board *Pages i* * Obstetric Anaesthesia* Failed intubation in obstetrics Review Article *Pages 357-364* Rhys Clayton, Jehan Abdulmajeed Regional anaesthesia for caesarean section and what to do if it fails Review Article *Pages 365-368* Sophie A. Kimber Craig Post-dural puncture headache in the parturient Review Article *Pages 369-371* Dipali Verma, Cathy Armstrong Neurological complic... περισσότερα »
Reconstructive Surgery
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 23 δευτερόλεπτα
Linear Separation of Toe Syndactyly With Preserved Subcutaneous Vascular Network Skin Grafts. T Aizawa, S Togashi, Y Haga, Y Nakayama, M Sekido… - Annals of *Plastic Surgery*, 2016 *...* Methods: A retrospective analysis was performed involving 66 patients with 88 syndactylic toes who presented to the department of *plastic* and *reconstructive* *surgery* at 1 of 3 major institutions during a 16-year period (1998-2014). *...* How Well Do They Convert? Trending ASAPS Presentations to Publication From 1995-2010 S Williams, A Pirlamarla, W Rahal, K Weichman… - Aesthetic *Surgery *Journ... περισσότερα »
Lichen striatus with syringotropism and hyperplasia of eccrine gland cells: A rare phenomenon that should not be confused with syringotropic mycosis fungoides
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Abstract Background Syringotropism is characterized by lymphocyte infiltration in the eccrine gland and is usually associated with various degrees of hyperplasia of eccrine gland cells. This phenomenon has been reported in rare cases of mycosis fungoides, which are also called as syringotropic mycosis fungoides. Methods We studied 7 cases of lichen striatus associated with syringotropism and hyperplasia of eccrine gland cells diagnosed at our dermatology department in the past 5 years. The hematoxylin and eosin stained slides from these cases were analyzed, and immunohistochemica... περισσότερα »
Patient experience and anxiety during and after treatment for an HPV-related oropharyngeal cancer
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Publication date: September 2016 *Source:*Oral Oncology, Volume 60 Author(s): Gypsyamber D'Souza, Yuehan Zhang, Samantha Merritt, Dorothy Gold, Hilary A. Robbins, Victoria Buckman, Jennifer Gerber, David W. Eisele, Patrick Ha, Joseph Califano, Carole Fakhry ObjectivesDiagnosis with an HPV-related oropharyngeal cancer includes unique social issues. However, it is unknown how common these psychosocial issues are for patients and whether they continue after treatment.Materials and methodsPatients with pathologically confirmed HPV-positive oropharyngeal cancer (HPV-OPC, n=48) were recru... περισσότερα »
Is oral cancer incidence among patients with oral lichen planus/oral lichenoid lesions underestimated?
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Background Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are considered potentially malignant disorders with a cancer incidence of around 1% of cases, although this estimation is controversial. The aim of this study was to analyze the cancer incidence in a case series of patients with OLP and OLL and to explore clinicopathological aspects that may cause underestimation of the cancer incidence in these diseases. Methods A retrospective study was conducted of 102 patients diagnosed with OLP (*n* = 21, 20.58%) or OLL (*n* = 81) between January 2006 and January 2016. Pat... περισσότερα »
Patient experience and anxiety during and after treatment for an HPV-related oropharyngeal cancer
Publication date: September 2016 *Source:*Oral Oncology, Volume 60 Author(s): Gypsyamber D'Souza, Yuehan Zhang, Samantha Merritt, Dorothy Gold, Hilary A. Robbins, Victoria Buckman, Jennifer Gerber, David W. Eisele, Patrick Ha, Joseph Califano, Carole Fakhry ObjectivesDiagnosis with an HPV-related oropharyngeal cancer includes unique social issues. However, it is unknown how common these psychosocial issues are for patients and whether they continue after treatment.Materials and methodsPatients with pathologically confirmed HPV-positive oropharyngeal cancer (HPV-OPC, n=48) were recru... περισσότερα »
Ethmoid Silent Sinus Syndrome Following Orbital Trauma.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Ethmoid Silent Sinus Syndrome Following Orbital Trauma.: A 55-year-old man presented with progressive «enophthalmos» of his ocular prosthesis, 12 years after secondary orbital implant placement following evisceration of a severe traumatic globe rupture. The medial orbital wall was found to be displaced inwards, associated with ethmoid sinus opacification, and consistent with post traumatic silent sinus […]
Partial Orbicularis Resection for the Augmentation of Traditional Internal Brow Pexy: The «Tuck and Rise».
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Partial Orbicularis Resection for the Augmentation of Traditional Internal Brow Pexy: The «Tuck and Rise».: Purpose: Brow ptosis commonly occurs with aging. Minimally invasive techniques are varied and include neurotoxin paralysis of eyebrow depressors and internal brow pexy. The authors present a modification of the traditional brow-pexy surgery which incorporates weakening of the lateral eyebrow […]
Efficacy of Muller’s Muscle and Conjunctiva Resection With or Without Tarsectomy for the Treatment of Severe Involutional Blepharoptosis.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Efficacy of Muller’s Muscle and Conjunctiva Resection With or Without Tarsectomy for the Treatment of Severe Involutional Blepharoptosis.: Purpose: To determine if Muller’s muscle and conjunctiva resection with or without tarsectomy is an efficacious procedure for the treatment of severe involutional blepharoptosis. Methods: A retrospective chart review was performed for all consecutive patients with severe […]
Effect of Manuka Honey on Eyelid Wound Healing: A Randomized Controlled Trial.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Effect of Manuka Honey on Eyelid Wound Healing: A Randomized Controlled Trial.: Purpose: To report outcomes of a randomized trial on the role of «active» Manuka honey on eyelid surgical wound healing. Method: Prospective, randomized, single-blinded study was performed for patients undergoing bilateral upper blepharoplasty. Vaseline was applied 4 times a day to both sides […]
Surgical Microanatomy of Lower Eyelid Tarsal Ectropion Repair With a Putterman Ptosis Clamp.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Surgical Microanatomy of Lower Eyelid Tarsal Ectropion Repair With a Putterman Ptosis Clamp.: Purpose: To examine the changes in microscopic anatomy of the lower eyelid tarsal ectropion repair with the Putterman ptosis clamp and better understand the anatomical changes associated with the eyelid malposition correction. Methods: Ten orbits from 5 fresh frozen cadaver heads, ranging […]
Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discussion of the diagnosis and treatment
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Publication date: Available online 16 July 2016Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Zoghlami, N. Bon Mardion, F. Callonnec, D. Dehesdin, F. Proust, J.-P. MarieIntroductionSkull base meningoencephaloceles are rare congenital malformations. The two cases of transalar transsphenoidal malformation reported here differ from the classical transsphenoidal meningoencephalocele.Case reportsCase 1 was a three-and-a-half-year-old boy […]
Pathways Linking Health Literacy, Health Beliefs, and Cognition to Medication Adherence in Older Adults with Asthma
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Publication date: Available online 16 July 2016Source:Journal of Allergy and Clinical Immunology Author(s): Tacara Soones, Jenny L. Lin, Michael S. Wolf, Rachel O’Conor, Melissa Martynenko, Juan P. Wisnivesky, Alex D. FedermanBackgroundLimited health literacy is associated with low adherence to asthma controller medications among older adults.ObjectiveWe sought to describe the causal pathway linking health literacy to […]
Pharmacological inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Publication date: Available online 16 July 2016Source:Journal of Allergy and Clinical Immunology Author(s): Asuka Honjo, Nobuhiro Nakano, Susumu Yamazaki, Mutsuko Hara, Koichiro Uchida, Jiro Kitaura, Chiharu Nishiyama, Hideo Yagita, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki ShimizuBackgroundMucosal mast cells (MMCs) play a central role in the development of symptoms associated with IgE-mediated food allergy. Recently, […]
Restrictive interleukin-10 induction by an innocuous Parainfluenza virus vector ameliorates nasal allergy
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Publication date: Available online 16 July 2016Source:Journal of Allergy and Clinical Immunology Author(s): Keiichi Yamanaka, Takehisa Nakanishi, Kana Isono, Chisami Hasegawa, Hiroyasu Inada, Kento Mizutani, Yoshiaki Matsushima, Karin Okada, Tomotaka Mabuchi, Makoto Kondo, Akisa Yamagiwa, Masato Kakeda, Koji Habe, Tetsuya Nosaka M, Esteban C. Gabazza, Hidetoshi Yamazaki, Hitoshi Mizutani, Mitsuo Kawano Teaser A novel therapy: […]
Early and late B cell developmental impairment in NFKB1 mutated CVID disease
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Publication date: Available online 16 July 2016Source:Journal of Allergy and Clinical Immunology Author(s): Vassilios Lougaris, Daniele Moratto, Manuela Baronio, Giacomo Tampella, Jos W.M. van der Meer, Raffaele Badolato, Manfred Fliegauf, Alessandro Plebani Teaser This study provides evidence for a novel role for NFKB1 in human B cell development, both in the bone marrow and in […]
Pathways Linking Health Literacy, Health Beliefs, and Cognition to Medication Adherence in Older Adults with Asthma
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tacara Soones, Jenny L. Lin, Michael S. Wolf, Rachel O'Conor, Melissa Martynenko, Juan P. Wisnivesky, Alex D. Federman BackgroundLimited health literacy is associated with low adherence to asthma controller medications among older adults.ObjectiveWe sought to describe the causal pathway linking health literacy to medication adherence by modeling asthma illness and medication beliefs as mediators.MethodsWe recruited adults age 60 and older with asthma f... περισσότερα »
Pharmacological inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Asuka Honjo, Nobuhiro Nakano, Susumu Yamazaki, Mutsuko Hara, Koichiro Uchida, Jiro Kitaura, Chiharu Nishiyama, Hideo Yagita, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu BackgroundMucosal mast cells (MMCs) play a central role in the development of symptoms associated with IgE-mediated food allergy. Recently, Notch2-mediated signaling was shown to be involved in proper MMC distribution in the intestinal tract.ObjectiveThis study aimed to clarify the mechani... περισσότερα »
Restrictive interleukin-10 induction by an innocuous Parainfluenza virus vector ameliorates nasal allergy
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Keiichi Yamanaka, Takehisa Nakanishi, Kana Isono, Chisami Hasegawa, Hiroyasu Inada, Kento Mizutani, Yoshiaki Matsushima, Karin Okada, Tomotaka Mabuchi, Makoto Kondo, Akisa Yamagiwa, Masato Kakeda, Koji Habe, Tetsuya Nosaka M, Esteban C. Gabazza, Hidetoshi Yamazaki, Hitoshi Mizutani, Mitsuo Kawano Teaser A novel therapy: Topical interleukin-10 application via non-replicating human Parainfluenza type 2 virus vector ameliorates mouse cedar pollinosis wi... περισσότερα »
Clinical spectrum and features of activated PI3-kinase delta syndrome: a large patient cohort study
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tanya I. Coulter, Anita Chandra, Chris M. Bacon, Judith Babar, James Curtis, Nick Screaton, John R. Goodlad, George Farmer, Cathal Laurence Steele, Timothy Ronan Leahy, Rainer Doffinger, Helen Baxendale, Jolanta Bernatoniene, J.D.M. Edgar, Hilary J. Longhurst, Stephan Ehl, Carsten Speckmann, Bodo Grimbacher, Anna Sediva, Tomas Milota, Saul N. Faust, Anthony P. Williams, Grant Hayman, Zeynep Yesim Kucuk, Rosie Hague, Paul French, Richard Brooker, Peter Forsyth, Richard Herri... περισσότερα »
Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis
Publication date: Available online 17 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Bianca Balbino, Riccardo Sibilano, Philipp Starkl, Thomas Marichal, Nicolas Gaudenzio, Hajime Karasuyama, Pierre Bruhns, Mindy Tsai, Laurent L. Reber, Stephen J. Galli BackgroundConflicting results have been obtained regarding roles of Fc receptors and effector cells in models of active systemic anaphylaxis (ASA). In part, this might reflect the choice of adjuvant used during sensitization, as various adjuvants might differentially influence the production of particular ant... περισσότερα »
Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discussion of the diagnosis and treatment
Publication date: Available online 16 July 2016 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Zoghlami, N. Bon Mardion, F. Callonnec, D. Dehesdin, F. Proust, J.-P. Marie IntroductionSkull base meningoencephaloceles are rare congenital malformations. The two cases of transalar transsphenoidal malformation reported here differ from the classical transsphenoidal meningoencephalocele.Case reportsCase 1 was a three-and-a-half-year-old boy and case 2 was a 36-year-old man. Both cases presented with clinical features of recurrent meningitis. Surgical... περισσότερα »
Pathways Linking Health Literacy, Health Beliefs, and Cognition to Medication Adherence in Older Adults with Asthma
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tacara Soones, Jenny L. Lin, Michael S. Wolf, Rachel O'Conor, Melissa Martynenko, Juan P. Wisnivesky, Alex D. Federman BackgroundLimited health literacy is associated with low adherence to asthma controller medications among older adults.ObjectiveWe sought to describe the causal pathway linking health literacy to medication adherence by modeling asthma illness and medication beliefs as mediators.MethodsWe recruited adults age 60 and older with asthma f... περισσότερα »
Body fat mass distribution and interrupter resistance, fractional exhaled nitric oxide and asthma at school-age
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Herman T. den Dekker, Karen PI. Ros, Johan C. de Jongste, Irwin K. Reiss, Vincent WV. Jaddoe, Liesbeth Duijts BackgroundObesity and asthma often coexist. We hypothesized that detailed body fat distribution measures might be more strongly associated with childhood asthma than body mass index (BMI).ObjectiveWe examined the associations of total body and abdominal fat measures with respiratory resistance (Rint), fractional exhaled nitric oxide (FeNO), and the risks of wheezing... περισσότερα »
Pharmacological inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Asuka Honjo, Nobuhiro Nakano, Susumu Yamazaki, Mutsuko Hara, Koichiro Uchida, Jiro Kitaura, Chiharu Nishiyama, Hideo Yagita, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu BackgroundMucosal mast cells (MMCs) play a central role in the development of symptoms associated with IgE-mediated food allergy. Recently, Notch2-mediated signaling was shown to be involved in proper MMC distribution in the intestinal tract.ObjectiveThis study aimed to clarify the mechani... περισσότερα »
Restrictive interleukin-10 induction by an innocuous Parainfluenza virus vector ameliorates nasal allergy
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Keiichi Yamanaka, Takehisa Nakanishi, Kana Isono, Chisami Hasegawa, Hiroyasu Inada, Kento Mizutani, Yoshiaki Matsushima, Karin Okada, Tomotaka Mabuchi, Makoto Kondo, Akisa Yamagiwa, Masato Kakeda, Koji Habe, Tetsuya Nosaka M, Esteban C. Gabazza, Hidetoshi Yamazaki, Hitoshi Mizutani, Mitsuo Kawano Teaser A novel therapy: Topical interleukin-10 application via non-replicating human Parainfluenza type 2 virus vector ameliorates mouse cedar pollinosis wi... περισσότερα »
Primary immunodeficiency diseases – genomic approaches delineate heterogeneous Mendelian disorders
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Asbjørg Stray-Pedersen, Hanne Sørmo Sorte, Pubudu Samarakoon, Tomasz Gambin, Ivan K. Chinn, Zeynep H. Coban Akdemir, Hans Christian Erichsen, Lisa R. Forbes, Shen Gu, Bo Yuan, Shalini N. Jhangiani, Donna M. Muzny, Olaug Kristin Rødningen, Ying Sheng, Sarah K. Nicholas, Lenora M. Noroski, Filiz O. Seeborg, Carla Davis, Debra Canter, Emily M. Mace, Tim Vece, Carl E. Allen, Harshal A. Abhyankar, Phil Boone, Christine R. Beck, Wojciech Krysztof Wiszniewski, Børre Fevang, Pål Au... περισσότερα »
Early and late B cell developmental impairment in NFKB1 mutated CVID disease
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Vassilios Lougaris, Daniele Moratto, Manuela Baronio, Giacomo Tampella, Jos W.M. van der Meer, Raffaele Badolato, Manfred Fliegauf, Alessandro Plebani Teaser This study provides evidence for a novel role for NFKB1 in human B cell development, both in the bone marrow and in the periphery, and in particular in the expansion of CD21lo B cells, a subset of innate-like B cells associated with autoimmune phaenomena, with evident implications in clinical co... περισσότερα »
Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discussion of the diagnosis and treatment
Publication date: Available online 16 July 2016 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Zoghlami, N. Bon Mardion, F. Callonnec, D. Dehesdin, F. Proust, J.-P. Marie IntroductionSkull base meningoencephaloceles are rare congenital malformations. The two cases of transalar transsphenoidal malformation reported here differ from the classical transsphenoidal meningoencephalocele.Case reportsCase 1 was a three-and-a-half-year-old boy and case 2 was a 36-year-old man. Both cases presented with clinical features of recurrent meningitis. Surgical... περισσότερα »
Extended applications of the endoscopic modified Lothrop procedure
Research Articles N Choudhury, A Hariri, H Saleh The Journal of Laryngology & Otology,FirstView Article(s), 6 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] http://ift.tt/29O8h56 http://ift.tt/29P3Ubl OtoRhinoLaryngology by Alexandros G. Sfakianakis
Occupational contact urticaria caused by food – a systematic clinical review
Summary Food industry workers are at increased risk for occupational contact urticaria (CU). There are many foodstuffs that have been reported to cause occupational CU, including seafood, meat, vegetables, and fruits. The aim of this review is to summarize all reported occupational cases of CU in the food industry. This is a systematic review based on a MEDLINE search of articles in English and German and a manual search, between 1990 and 2014, to summarize the case reports and case series of occupational CU in the food industry. Many different foodstuffs have been implicated in CU... περισσότερα »
Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discussion of the diagnosis and treatment
Publication date: Available online 16 July 2016 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Zoghlami, N. Bon Mardion, F. Callonnec, D. Dehesdin, F. Proust, J.-P. Marie IntroductionSkull base meningoencephaloceles are rare congenital malformations. The two cases of transalar transsphenoidal malformation reported here differ from the classical transsphenoidal meningoencephalocele.Case reportsCase 1 was a… Continue reading Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discus... περισσότερα »
Symposium on ‘Evolving approaches for studying the anatomy of the avian brain’: introduction
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Pathways Linking Health Literacy, Health Beliefs, and Cognition to Medication Adherence in Older Adults with Asthma
Publication date: Available online 16 July 2016 Source:Journal of Allergy and Clinical Immunology Author(s): Tacara Soones, Jenny L. Lin, Michael S. Wolf, Rachel O’Conor, Melissa Martynenko, Juan P. Wisnivesky, Alex D. Federman BackgroundLimited health literacy is associated with low adherence to asthma controller medications among older adults.ObjectiveWe sought to describe the causal pathway linking health… Continue reading Pathways Linking Health Literacy, Health Beliefs, and Cognition to Medication Adherence in Older Adults with Asthma
Pharmacological inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia
Publication date: Available online 16 July 2016 Source:Journal of Allergy and Clinical Immunology Author(s): Asuka Honjo, Nobuhiro Nakano, Susumu Yamazaki, Mutsuko Hara, Koichiro Uchida, Jiro Kitaura, Chiharu Nishiyama, Hideo Yagita, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu BackgroundMucosal mast cells (MMCs) play a central role in the development of symptoms associated with IgE-mediated food… Continue reading Pharmacological inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia
Early and late B cell developmental impairment in NFKB1 mutated CVID disease
Publication date: Available online 16 July 2016 Source:Journal of Allergy and Clinical Immunology Author(s): Vassilios Lougaris, Daniele Moratto, Manuela Baronio, Giacomo Tampella, Jos W.M. van der Meer, Raffaele Badolato, Manfred Fliegauf, Alessandro Plebani Teaser This study provides evidence for a novel role for NFKB1 in human B cell development, both in the bone marrow and… Continue reading Early and late B cell developmental impairment in NFKB1 mutated CVID disease
Restrictive interleukin-10 induction by an innocuous Parainfluenza virus vector ameliorates nasal allergy
Publication date: Available online 16 July 2016 Source:Journal of Allergy and Clinical Immunology Author(s): Keiichi Yamanaka, Takehisa Nakanishi, Kana Isono, Chisami Hasegawa, Hiroyasu Inada, Kento Mizutani, Yoshiaki Matsushima, Karin Okada, Tomotaka Mabuchi, Makoto Kondo, Akisa Yamagiwa, Masato Kakeda, Koji Habe, Tetsuya Nosaka M, Esteban C. Gabazza, Hidetoshi Yamazaki, Hitoshi Mizutani, Mitsuo Kawano Teaser A novel… Continue reading Restrictive interleukin-10 induction by an innocuous Parainfluenza virus vector ameliorates nasal allergy
Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis
Publication date: Available online 17 July 2016 Source:Journal of Allergy and Clinical Immunology Author(s): Bianca Balbino, Riccardo Sibilano, Philipp Starkl, Thomas Marichal, Nicolas Gaudenzio, Hajime Karasuyama, Pierre Bruhns, Mindy Tsai, Laurent L. Reber, Stephen J. Galli BackgroundConflicting results have been obtained regarding roles of Fc receptors and effector cells in models of active systemic anaphylaxis… Continue reading Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis
Clinical spectrum and features of activated PI3-kinase delta syndrome: a large patient cohort study
Publication date: Available online 16 July 2016 Source:Journal of Allergy and Clinical Immunology Author(s): Tanya I. Coulter, Anita Chandra, Chris M. Bacon, Judith Babar, James Curtis, Nick Screaton, John R. Goodlad, George Farmer, Cathal Laurence Steele, Timothy Ronan Leahy, Rainer Doffinger, Helen Baxendale, Jolanta Bernatoniene, J.D.M. Edgar, Hilary J. Longhurst, Stephan Ehl, Carsten Speckmann, Bodo… Continue reading Clinical spectrum and features of activated PI3-kinase delta syndrome: a large patient cohort study
Primary immunodeficiency diseases – genomic approaches delineate heterogeneous Mendelian disorders
Publication date: Available online 16 July 2016 Source:Journal of Allergy and Clinical Immunology Author(s): Asbjørg Stray-Pedersen, Hanne Sørmo Sorte, Pubudu Samarakoon, Tomasz Gambin, Ivan K. Chinn, Zeynep H. Coban Akdemir, Hans Christian Erichsen, Lisa R. Forbes, Shen Gu, Bo Yuan, Shalini N. Jhangiani, Donna M. Muzny, Olaug Kristin Rødningen, Ying Sheng, Sarah K. Nicholas, Lenora… Continue reading Primary immunodeficiency diseases – genomic approaches delineate heterogeneous Mendelian disorders
3-D View of Mutations May Identify Potential Targets for Cancer Drugs
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
3-D View of Mutations May Identify Potential Targets for Cancer Drugs 07/14/2016 A new computational tool may help expand the known number of mutations in cancer cells that could be targeted with new or existing drugs. Researchers recently reported that the tool, called HotSpot3D, allowed them to model how genetic mutations change the ways proteins function and interact with each other to potentially drive cancer. It also helped them identify more than 800 novel mutations that potentially could be targeted with existing drugs.
Experimental and Therapeutic Medicine
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
[image: Biomedical Reports] TABLE OF CONTENTS August 2016 Volume 12 Issue 2[image: View Issue] [Editorial] The subspecialty of Paediatric Virology: A ‘mosaic tile’ in future Paediatrics Ioannis Mammas, Demetrios Spandidos View Abstract ❯ Paediatric Virology in the Hippocratic Corpus (Review) Ioannis Mammas, Demetrios Spandidos View Abstract ❯ Effects of plyometric training on soccer players (Review) Ying-Chun Wang, Na Zhang View Abstract ❯ Magnetic resonance imaging in pediatric sickle cell anemia (Review) Xinxian Zhang, Chenglong Li, Qiancheng Li View Abstract ❯ Comparison of oxycodone ... περισσότερα »
Antonie van Leeuwenhoek
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Original Paper *Steroidobacter flavus* sp. nov., a microcystin-degrading Gammaproteobacterium isolated from soil Zhi-Lian Gong, Chang-Feng Zhang, Rong Jin & Yu-Qin Zhang » Abstract » Full text HTML » Full text PDF Original Paper Effects of *CTR4* deletion on virulence and stress response in *Cryptococcus neoformans* Ping Zhang, Defa Zhang, Xueru Zhao, Dongsheng Wei, Yu Wang & Xudong Zhu » Abstract » Full text HTML » Full text PDF Original Paper *Thalassospira australica* sp. nov. isolated from sea water Elena P. Ivanova, Mario López-Pérez, Hayden K. Webb, Hooi Jun Ng, Thi Hoa... περισσότερα »
Breast Cancer Research and Treatment
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Review Weight gain during adjuvant endocrine treatment for early-stage breast cancer: What is the evidence? K. A. Nyrop, G. R. Williams, H. B. Muss & S. S. Shachar » Abstract » Full text HTML » Full text PDF Review Recurrent and pathological gene fusions in breast cancer: current advances in genomic discovery and clinical implications Jamunarani Veeraraghavan, Jiacheng Ma, Yiheng Hu & Xiao-Song Wang » Abstract » Full text HTML » Full text PDF Preclinical study Loss of ataxia-telangiectasia-mutated protein expression correlates with poor prognosis but benefits from anthracycli... περισσότερα »
Endobariatrics
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
New antibiotics targeting MDR pathogens are expensive, but not impressive LORI LAUBACH ------------------------------ Eight recently approved antibiotics targeting multidrug-resistant bacteria have not led to a substantial improvement in patient outcomes when compared with existing antibiotics, new research reveals.... »» Read more [image: Advertisement] Retiring Baby Boomers leave fewer workers to pay for Medicare RICHARD FRANKI ------------------------------ The influx of aging Baby Boomers into the ranks of the retired will reduce the ratio of workers available to pay for each Med... περισσότερα »
International Wound Journal © John Wiley & Sons Ltd and Medicalhelplines.com Inc.
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Volume 13, Issue 4 Pages 433 - 585, August 2016 The latest issue of International Wound Journal is available on Wiley Online Library ISSUE INFORMATION Issue Information – JIP (page 433) Version of Record online: 11 JUL 2016 | DOI: 10.1111/iwj.12512 Issue Information – Aims and Scope (pages 434–435) Version of Record online: 11 JUL 2016 | DOI: 10.1111/iwj.12511 EDITORIAL *International Wound Journal* impact factor increases year on year (pages 437–438) Douglas Queen and Keith Harding Version of Record online: 11 JUL 2016 | DOI: 10.1111/iwj.12651 NEWS Society News (pages 439–440) Vers... περισσότερα »
Training and Research
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
A comparative study of Transcanalicular Diode Laser Supported Endoscopic Dacryocystorhinostomy and Non-laser Endoscopic Dacryocystorhinostomy G Övet, Y Sakarya - American Journal of Otolaryngology, 2016 *...* Affiliations. Medical Sciences University, *Training* *and* *Research* *Hospital*, Department of Otorhinolaryngology, Konya, Turkey. *...* Corresponding author at: Medical Sciences University, *Training* *and* *Research* *Hospital*, Department of Otorhinolaryngology, Hacı Şaban Mah. *...* Primary Tumor Resection and Survival in Patients with Stage IV Gastric Cancer FY Müsri, H ... περισσότερα »
Platelet derived growth factor-BB
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Irisin reverses *platelet derived growth factor*-BB-induced vascular smooth muscle cells phenotype modulation through STAT3 signaling pathway H Song, J Xu, N Lv, Y Zhang, F Wu, H Li, L Shao, Q Mu… - … and Biophysical Research …, 2016 Abstract Vascular smooth muscle cells (VSMCs) phenotype modulation toward a synthetic phenotype is the main cause of cardiovascular disease. As a newly discovered myokine, Irisin is thought to be a promising candidate for the treatment of metabolic disturbances, as *...* Suppressive effect of formononetin on *platelet*-*derived growth factor*-BB-stimula... περισσότερα »
Laser
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
[HTML] Venolymphatic vascular malformation of the parotid gland extending into the parapharyngeal space: A rare presentation Y Khatib, M Dande, RD Patel, V Gite - Journal of *Oral *and Maxillofacial Pathology, 2016 *...* of Pathology, Dr. RN Cooper Hospital, Mumbai, Maharashtra, India 2 Department of *ENT*, Dr. RN *...* [3] Nearly 50% VMs occur in the head and neck region with lip, *oral* cavity, tongue *...* *Laser*therapy using neodymium: Yttrium-aluminum-garnet *laser* is also used in some cases. [12] *...* [HTML] Efficacy, outcomes, and complication rates of different surgical a... περισσότερα »
Fistulas
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Traumatic Pseudoaneurysm of the External Carotid Artery with Arteriovenous *Fistula *Treated with Endosaccular Embolization H Ikeda, H Imamura, H Adachi, Y Ueno, T Ishikawa… - Journal of …, 2016 *...* He underwent *bilateral* mandibular sagittal split ramus osteotomy under general anesthesia for mandibu *...* Since the *neck* of pseudoaneurysms is usually much smaller than the dome,10 *...*Generally, also, there is only one communication in traumatic arteriovenous *fistulas*,10) and *...* Critical Care Issues in Oncologic Surgery Patients KP Patel, K Hale, SM Pastores - Surgical Inte... περισσότερα »
Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discussion of the diagnosis and treatment
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
Publication date: Available online 16 July 2016 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Zoghlami, N. Bon Mardion, F. Callonnec, D. Dehesdin, F. Proust, J.-P. Marie IntroductionSkull base meningoencephaloceles are rare congenital malformations. The two cases of transalar transsphenoidal malformation reported here differ from the classical transsphenoidal meningoencephalocele.Case reportsCase 1 was a three-and-a-half-year-old boy and case 2 was a 36-year-old man. Both cases presented with clinical features of recurrent meningitis. Surgical... περισσότερα »
Pathways Linking Health Literacy, Health Beliefs, and Cognition to Medication Adherence in Older Adults with Asthma
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tacara Soones, Jenny L. Lin, Michael S. Wolf, Rachel O’Conor, Melissa Martynenko, Juan P. Wisnivesky, Alex D. Federman BackgroundLimited health literacy is associated with low adherence to asthma controller medications among older adults.ObjectiveWe sought to describe the causal pathway linking health literacy to medication adherence by modeling asthma illness and medication beliefs as mediators.MethodsWe recruited adults age 60 and older with asthma f... περισσότερα »
Restrictive interleukin-10 induction by an innocuous Parainfluenza virus vector ameliorates nasal allergy
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Keiichi Yamanaka, Takehisa Nakanishi, Kana Isono, Chisami Hasegawa, Hiroyasu Inada, Kento Mizutani, Yoshiaki Matsushima, Karin Okada, Tomotaka Mabuchi, Makoto Kondo, Akisa Yamagiwa, Masato Kakeda, Koji Habe, Tetsuya Nosaka M, Esteban C. Gabazza, Hidetoshi Yamazaki, Hitoshi Mizutani, Mitsuo Kawano Teaser A novel therapy: Topical interleukin-10 application via non-replicating human Parainfluenza type 2 virus vector ameliorates mouse cedar pollinosis wi... περισσότερα »
Early and late B cell developmental impairment in NFKB1 mutated CVID disease
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Vassilios Lougaris, Daniele Moratto, Manuela Baronio, Giacomo Tampella, Jos W.M. van der Meer, Raffaele Badolato, Manfred Fliegauf, Alessandro Plebani Teaser This study provides evidence for a novel role for NFKB1 in human B cell development, both in the bone marrow and in the periphery, and in particular in the expansion of CD21lo B cells, a subset of innate-like B cells associated with autoimmune phaenomena, with evident implications in clinical co... περισσότερα »
Pharmacological inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Asuka Honjo, Nobuhiro Nakano, Susumu Yamazaki, Mutsuko Hara, Koichiro Uchida, Jiro Kitaura, Chiharu Nishiyama, Hideo Yagita, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu BackgroundMucosal mast cells (MMCs) play a central role in the development of symptoms associated with IgE-mediated food allergy. Recently, Notch2-mediated signaling was shown to be involved in proper MMC distribution in the intestinal tract.ObjectiveThis study aimed to clarify the mechani... περισσότερα »
Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
Publication date: Available online 17 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Bianca Balbino, Riccardo Sibilano, Philipp Starkl, Thomas Marichal, Nicolas Gaudenzio, Hajime Karasuyama, Pierre Bruhns, Mindy Tsai, Laurent L. Reber, Stephen J. Galli BackgroundConflicting results have been obtained regarding roles of Fc receptors and effector cells in models of active systemic anaphylaxis (ASA). In part, this might reflect the choice of adjuvant used during sensitization, as various adjuvants might differentially influence the production of particular ant... περισσότερα »
Clinical spectrum and features of activated PI3-kinase delta syndrome: a large patient cohort study
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tanya I. Coulter, Anita Chandra, Chris M. Bacon, Judith Babar, James Curtis, Nick Screaton, John R. Goodlad, George Farmer, Cathal Laurence Steele, Timothy Ronan Leahy, Rainer Doffinger, Helen Baxendale, Jolanta Bernatoniene, J.D.M. Edgar, Hilary J. Longhurst, Stephan Ehl, Carsten Speckmann, Bodo Grimbacher, Anna Sediva, Tomas Milota, Saul N. Faust, Anthony P. Williams, Grant Hayman, Zeynep Yesim Kucuk, Rosie Hague, Paul French, Richard Brooker, Peter Forsyth, Richard Herri... περισσότερα »
Body fat mass distribution and interrupter resistance, fractional exhaled nitric oxide and asthma at school-age
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Herman T. den Dekker, Karen PI. Ros, Johan C. de Jongste, Irwin K. Reiss, Vincent WV. Jaddoe, Liesbeth Duijts BackgroundObesity and asthma often coexist. We hypothesized that detailed body fat distribution measures might be more strongly associated with childhood asthma than body mass index (BMI).ObjectiveWe examined the associations of total body and abdominal fat measures with respiratory resistance (Rint), fractional exhaled nitric oxide (FeNO), and the risks of wheezing... περισσότερα »
Primary immunodeficiency diseases – genomic approaches delineate heterogeneous Mendelian disorders
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Asbjørg Stray-Pedersen, Hanne Sørmo Sorte, Pubudu Samarakoon, Tomasz Gambin, Ivan K. Chinn, Zeynep H. Coban Akdemir, Hans Christian Erichsen, Lisa R. Forbes, Shen Gu, Bo Yuan, Shalini N. Jhangiani, Donna M. Muzny, Olaug Kristin Rødningen, Ying Sheng, Sarah K. Nicholas, Lenora M. Noroski, Filiz O. Seeborg, Carla Davis, Debra Canter, Emily M. Mace, Tim Vece, Carl E. Allen, Harshal A. Abhyankar, Phil Boone, Christine R. Beck, Wojciech Krysztof Wiszniewski, Børre Fevang, Pål Au... περισσότερα »
Extended applications of the endoscopic modified Lothrop procedure
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
Research Articles N Choudhury, A Hariri, H Saleh The Journal of Laryngology & Otology,FirstView Article(s), 6 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] http://ift.tt/29O8h56
Regulation of Inflammation by Lipid Mediators in Oral Diseases
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 59 δευτερόλεπτα
Abstract Lipid mediators (LM) of inflammation are a class of compounds derived from *ω*-3 and *ω*-6 fatty acids that play a wide role in modulating inflammatory responses. Some LM possess pro-inflammatory properties, while others possess pro-resolving characteristics, and the class switch from pro-inflammatory to pro-resolving is crucial for tissue homeostasis. In this article, we review the major classes of LM, focusing on their biosynthesis and signaling pathways, and their role in systemic and, especially, oral health and disease. We discuss the detection of these LM in various... περισσότερα »
Symposium on ‘Evolving approaches for studying the anatomy of the avian brain’: introduction
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
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Announcement
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
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Symposium on ‘Evolving approaches for studying the anatomy of the avian brain’: introduction
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Announcement
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Symposium on ‘Evolving approaches for studying the anatomy of the avian brain’: introduction
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Announcement
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Symposium on ‘Evolving approaches for studying the anatomy of the avian brain’: introduction
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
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Announcement
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
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Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discussion of the diagnosis and treatment
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 16 July 2016 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Zoghlami, N. Bon Mardion, F. Callonnec, D. Dehesdin, F. Proust, J.-P. Marie IntroductionSkull base meningoencephaloceles are rare congenital malformations. The two cases of transalar transsphenoidal malformation reported here differ from the classical transsphenoidal meningoencephalocele.Case reportsCase 1 was a three-and-a-half-year-old boy and case 2 was a 36-year-old man. Both cases presented with clinical features of recurrent meningitis. Surgical... περισσότερα »
Pathways Linking Health Literacy, Health Beliefs, and Cognition to Medication Adherence in Older Adults with Asthma
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tacara Soones, Jenny L. Lin, Michael S. Wolf, Rachel O'Conor, Melissa Martynenko, Juan P. Wisnivesky, Alex D. Federman BackgroundLimited health literacy is associated with low adherence to asthma controller medications among older adults.ObjectiveWe sought to describe the causal pathway linking health literacy to medication adherence by modeling asthma illness and medication beliefs as mediators.MethodsWe recruited adults age 60 and older with asthma f... περισσότερα »
Pharmacological inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Asuka Honjo, Nobuhiro Nakano, Susumu Yamazaki, Mutsuko Hara, Koichiro Uchida, Jiro Kitaura, Chiharu Nishiyama, Hideo Yagita, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu BackgroundMucosal mast cells (MMCs) play a central role in the development of symptoms associated with IgE-mediated food allergy. Recently, Notch2-mediated signaling was shown to be involved in proper MMC distribution in the intestinal tract.ObjectiveThis study aimed to clarify the mechani... περισσότερα »
Restrictive interleukin-10 induction by an innocuous Parainfluenza virus vector ameliorates nasal allergy
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Keiichi Yamanaka, Takehisa Nakanishi, Kana Isono, Chisami Hasegawa, Hiroyasu Inada, Kento Mizutani, Yoshiaki Matsushima, Karin Okada, Tomotaka Mabuchi, Makoto Kondo, Akisa Yamagiwa, Masato Kakeda, Koji Habe, Tetsuya Nosaka M, Esteban C. Gabazza, Hidetoshi Yamazaki, Hitoshi Mizutani, Mitsuo Kawano Teaser A novel therapy: Topical interleukin-10 application via non-replicating human Parainfluenza type 2 virus vector ameliorates mouse cedar pollinosis wi... περισσότερα »
From focal sepsis to periodontal medicine: A century of exploring the role of the oral microbiome in systemic disease
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Abstract The oral microbiome is established within a few minutes after birth and forms stable multi-species communities that engage in a dynamic equilibrium with the host immune system. Dental caries, endodontic infections and periodontal diseases are bacterially driven diseases that are caused by dysbiotic microbiomes. Over a century ago, the focal infection theory implicated these infections in the etiology of several systemic diseases, ranging from arthritis to neurodegenerative diseases. However, a lack of concrete evidence, combined with the urgency with which clinicians embra... περισσότερα »
Left-right coordination from simple to extreme conditions during split-belt locomotion in the chronic spinal adult cat
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Abstract Although left-right coordination is essential for locomotion, its control is poorly understood, particularly in adult mammals. To investigate the spinal control of left-right coordination, a spinal transection was performed in six adult cats that were then trained to recover hindlimb locomotion. Spinal cats performed tied-belt locomotion from 0.1 m s−1 to 1.0 m s−1 and split-belt locomotion with low to high (1:1.25-10) slow-fast speed ratios. With the left hindlimb stepping at 0.1 m s−1 and the right hindlimb stepping from 0.2 m s−1 to 1.0 m s−1, 1:1, 1:2, 1:3, 1:4 and 1:5... περισσότερα »
In vivo matching of postsynaptic excitability with spontaneous synaptic inputs during formation of the rat calyx of Held synapse
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Abstract In the adult, principal neurons of the medial nucleus of the trapezoid body (MNTB) are typically contacted by a single, giant terminal called the calyx of Held, whereas during early development a principal neuron receives inputs from many axons. How these changes in innervation impact the postsynaptic activity has not yet been studied *in vivo*. We therefore recorded spontaneous inputs and intrinsic properties of principal neurons in anesthetized rat pups during the developmental period in which the calyx forms. A characteristic bursting pattern could already be observed ... περισσότερα »
Exogenous and endogenous angiotensin-ii decrease renal cortical oxygen tension in conscious rats by limiting renal blood flow
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
We hypothesised that both exogenous and endogenous angiotensin-II (AngII) can decrease the partial pressure of oxygen (pO2) in the renal cortex of unrestrained rats, which might in turn contribute to the progression of chronic kidney disease. Rats were instrumented with telemeters equipped with a carbon paste electrode for continuous measurement of renal cortical tissue pO2. The method reproducibly detected acute changes in cortical oxygenation induced by systemic hyperoxia and hypoxia. In conscious rats, renal cortical pO2 was dose-dependently reduced by intravenous AngII. Reduc... περισσότερα »
Congenital heart diseases and their association with the variant distribution features on susceptibility genes
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Abstract Congenital heart disease (CHD), one cause of childhood morbidity and mortality, is mainly triggered by a combination of environmental and genetic factors. Several susceptible genes, such as *NKX2-5*, *GATA4* and *TBX5,* have been reported as closely related to heart and vessel development. CHD subtypes are classified by diverse clinical phenotypes such as atrial septal defects (ASD), ventricular septal defects (VSD), tetralogy of Fallot (TOF), and Holt-Oram syndrome (HOS). Here, we summarize the associations of the genetic variants in these three genes with CHD subtypes. ... περισσότερα »
CLOVES syndrome: review of a PIK3CA-Related Overgrowth Spectrum (PROS)
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Abstract Overgrowth syndromes are characterized by global or localized disproportionate growth associated with other anomalies, including vascular malformations and neurological and/or visceral disorders. CLOVES (Congenital Lipomatous asymmetric Overgrowth of the trunk with lymphatic, capillary, venous, and combined-type Vascular malformations, Epidermal naevi, Scoliosis/Skeletal and spinal anomalies) is an overgrowth syndrome caused by mosaic activating mutation in gene PIK3CA, which gives rise to abnormal PI3K-AKT-mTOR pathway activation. These mutations are responsible for the ... περισσότερα »
IJERPH, Vol. 13, Pages 722: The Short-Term Effect of Ambient Temperature on Mortality in Wuhan, China: A Time-Series Study Using a Distributed Lag Non-Linear Model
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Less evidence concerning the association between ambient temperature and mortality is available in developing countries/regions, especially inland areas of China, and few previous studies have compared the predictive ability of different temperature indictors (minimum, mean, and maximum temperature) on mortality. We assessed the effects of temperature on daily mortality from 2003 to 2010 in Jiang’an District of Wuhan, the largest city in central China. Quasi-Poisson generalized linear models combined with both non-threshold and double-threshold distributed lag non-linear models (DLN... περισσότερα »
Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discussion of the diagnosis and treatment
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 16 July 2016Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Zoghlami, N. Bon Mardion, F. Callonnec, D. Dehesdin, F. Proust, J.-P. Marie IntroductionSkull base meningoencephaloceles are rare congenital malformations. The two cases of transalar transsphenoidal malformation reported here differ from the classical transsphenoidal meningoencephalocele.Case reportsCase 1 was a three-and-a-half-year-old […]
Congenital heart diseases and their association with the variant distribution features on susceptibility genes
Abstract Congenital heart disease (CHD), one cause of childhood morbidity and mortality, is mainly triggered by a combination of environmental and genetic factors. Several susceptible genes, such as *NKX2-5*, *GATA4* and *TBX5,* have been reported as closely related to heart and vessel development. CHD subtypes are classified by diverse clinical phenotypes such as atrial septal defects (ASD), ventricular septal defects (VSD), tetralogy of Fallot (TOF), and Holt-Oram syndrome (HOS). Here, we summarize the associations of the genetic variants in these three genes with CHD subtypes. ... περισσότερα »
CLOVES syndrome: review of a PIK3CA-Related Overgrowth Spectrum (PROS)
Abstract Overgrowth syndromes are characterized by global or localized disproportionate growth associated with other anomalies, including vascular malformations and neurological and/or visceral disorders. CLOVES (Congenital Lipomatous asymmetric Overgrowth of the trunk with lymphatic, capillary, venous, and combined-type Vascular malformations, Epidermal naevi, Scoliosis/Skeletal and spinal anomalies) is an overgrowth syndrome caused by mosaic activating mutation in gene PIK3CA, which gives rise to abnormal PI3K-AKT-mTOR pathway activation. These mutations are responsible for the ... περισσότερα »
ENT Journal eNews
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
*A rare cause of conductive hearing loss: High lateralized jugular bulb with bony dehiscence* We present a rare case of pediatric conductive hearing loss due to a high lateralized jugular bulb. An 8-year-old boy with a right-sided conductive hearing loss of 40 dB was found to have a pink bulge toward the inferior part of the right eardrum. Computed tomography showed a high, lateralized right jugular bulb that had a superolaterally pointing diverticulum that bulged into the lower mesotympanum and posterior external auditory meatus. It was explained to the child's parents that it is... περισσότερα »
Journal of the Association for Research in Otolaryngology
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
Research Article Inherent Directionality Determines Spatial Release from Masking at the Tympanum in a Vertebrate with Internally Coupled Ears Michael S. Caldwell, Norman Lee & Mark A. Bee » Abstract » Full text HTML » Full text PDF Research Article Comparing Distortion Product Otoacoustic Emissions to Intracochlear Distortion Products Inferred from a Noninvasive Assay Glen K. Martin, Barden B. Stagner, Wei Dong & Brenda L. Lonsbury-Martin » Abstract » Full text HTML » Full text PDF Research Article Inhibitors of Histone Deacetylases Attenuate Noise-Induced Hearing Loss Jun Che... περισσότερα »
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology] Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Volume 122, Issue 2 , Pages A1-A12, e31-e76, 115-262, August 2016 Contents *Pages A5-A8* Editorial Board *Pages A9* Society Page *Pages A10* Information for Readers *Pages A11* * Editorial* Case reports: the perils of offering treatment recommendations that have not been critically appraised *Pages 115-116* Paul C. Edwards * Clinicopathologic Conference* *[image: Supplemental material]*Rapidly expanding mass of the maxilla and paranas... περισσότερα »
Oral Oncology
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: Oral Oncology] Oral Oncology Volume 59 , Pages e1-e14, 1-86, August 2016 Editorial Board/Aims & Scope *Pages i* * Review Articles* Unraveling the oral cancer lncRNAome: Identification of novel lncRNAs associated with malignant progression and HPV infection Review Article *Pages 58-66* Nijiro Nohata, Martin C. Abba, J. Silvio Gutkind Evaluation of the benefit and use of multidisciplinary teams in the treatment of head and neck cancer Review Article *Pages 73-79* Lisa Licitra, Ulrich Keilholz, Makoto Tahara, Jin-Ching Lin, Pauline Chomette, Philippe Ceruse, Kevin Harrin... περισσότερα »
Voice Disorders
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
Systems and Methodologies for Capturing Outgoing *Voice *Messages and Providing Secured Access Thereto A Misra, A Misra - US Patent 20,160,182,723, 2016 Abstract: A system and associated method is provided for capturing outgoing *voice * messages on a mobile communications device equipped with a display and a memory device. In accordance with the system, a software program is installed in the memory *...* MECHANISM TO PROVIDE LTE *VOICE*, INTERNET AND EMBMS SERVICES OVER ETHERNET FOR CONNECTED HOME ARCHITECTURE S Gupta, R Tripathi, K Lee, S Veerepalli, TB Wear… - US Patent 20,160,1... περισσότερα »
Thyroid cancer
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
Unemployment risk and decreased income 2 and 4 years after *thyroid cancer*diagnosis: a population based study NZ Ratzon, B Uziely, AGEM de Boer, Y Rottenberg - Thyroid, 2016 *...* G, Lundell G, Ljunggren JG, Taube A, Sääf M, Hamberger B 1996 Graves' hyperthyroidism: treatment with antithyroid drugs, *surgery*, or radioiodine--a *...* J, Segal P, Goguen J, Gilbert J, Zahedi A, Kelly C, Ezzat S 2014 Persistent posttreatment fatigue in *thyroid* *cancer* survivors: a *...* Implication of 18F‑fluorodeoxyglucose uptake by affected lymph nodes in cases with differentiated *thyroid cancer... περισσότερα »
Head and Neck Cancer
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
Pembrolizumab: the value of PDL1 biomarker in *head and neck cancer* R Addeo, M Caraglia, G Iuliano - 2016 As a service to authors and researchers we are providing this version of an accepted manuscript (AM). Copyediting, typesetting, and review of the resulting proofs will be undertaken on this manuscript before final publication of the Version of Record (VoR). *...* The Expression of Checkpoint and DNA Repair Genes in *Head and Neck Cancer *as Possible Predictive Factors O Rusz, M Pál, É Szilágyi, L Rovó, Z Varga, B Tomisa… - Pathology & Oncology …, 2016 Abstract DNA damage respon... περισσότερα »
Thyroid & Parathyroids
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
I-131 for Remnant *Ablation *in Differentiated *Thyroid *Cancer After Thyroidectomy: A Meta-Analysis of Randomized Controlled Evidence Y Shengguang, C Ji-Eun, HL Lijuan - Medical Science Monitor, 2016 *...* *thyroid* cancer, but the advantage of high activity seems to only exist in patients who underwent hemithyroidectomy/subtotal thyroidectomy, but not lymph node involvement, preparation before *ablation*, and definition of successful *ablation*. Keywords: meta-analysis, *Parathyroid* *...* Endocrine tumors associated with the vagus nerve A Varoquaux, E Kebebew, F Sebag, K Wolf, JF ... περισσότερα »
Squamous Cell Carcinoma
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
[PDF] Effect of Collagen Type I or Human Fibronectin on Imatinib Cytotoxicity in Oral *Squamous Cell Carcinoma* M Morioka, M Hazekawa, T Kawakubo-Yasukochi… - 2016 Abstract Extracellular matrix (ECM) components are critical for all aspects of cell proliferation, adhesion, and morphological alteration. Recent progress has yielded multiple molecular drugs that specifically target gene products which are expressed at high levels *...* Unusual presentation of *squamous cell carcinoma *of the maxilla in an 8-year-old child MAO Magalhaes, GR Somers, P Sikorski, V Forte… - Oral Surgery, Or... περισσότερα »
Obstructive Sleep Apnea
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
Clinical features in patients with positional *obstructive sleep apnea *according to its subtypes SA Lee, JH Paek, YS Chung, WS Kim - Sleep and Breathing, 2016 *...* *Obstructive* *sleep* *apnea* (OSA) syndrome is a common sleep disorder characterized by repetitive obstruction of the upper *...* movement with the output of signals for three directions and differentiates five *positions* including the supine and the non-supine *position* (right, left *...* Ventilator Support in Children with *Obstructive Sleep Apnea *Syndrome K Nandalike, R Arens - Caring for the Ventilator *Dependent... περισσότερα »
Allergy
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
[HTML] Sensitization and Clinically Relevant *Allergy *to Hair Dyes and Clothes from Black Henna Tattoos: Do People Know the Risk? An Uncommon Serious Case and a … PA Moro, M Morina, F Milani, M Pandolfi, F Guerriero… - Cosmetics, 2016 Abstract: Henna (Lawsonia inermis L.) tattooing has been used in Egypt and India since ancient times. Today this temporary body art is becoming increasingly popular among young people. Various chemicals are added to henna to darken and enhance the definition of *...* Mathematical models are not sufficient for the diagnosis of drug *allergy* I Doña, M ... περισσότερα »
Early and late B cell developmental impairment in NFKB1 mutated CVID disease
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Vassilios Lougaris, Daniele Moratto, Manuela Baronio, Giacomo Tampella, Jos W.M. van der Meer, Raffaele Badolato, Manfred Fliegauf, Alessandro Plebani Teaser This study provides evidence for a novel role for NFKB1 in human B cell development, both in the bone marrow and in the periphery, and in particular in the expansion of CD21lo B cells, a subset of innate-like B cells associated with autoimmune phaenomena, with evident implications in clinical co... περισσότερα »
Clinical spectrum and features of activated PI3-kinase delta syndrome: a large patient cohort study
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tanya I. Coulter, Anita Chandra, Chris M. Bacon, Judith Babar, James Curtis, Nick Screaton, John R. Goodlad, George Farmer, Cathal Laurence Steele, Timothy Ronan Leahy, Rainer Doffinger, Helen Baxendale, Jolanta Bernatoniene, J.D.M. Edgar, Hilary J. Longhurst, Stephan Ehl, Carsten Speckmann, Bodo Grimbacher, Anna Sediva, Tomas Milota, Saul N. Faust, Anthony P. Williams, Grant Hayman, Zeynep Yesim Kucuk, Rosie Hague, Paul French, Richard Brooker, Peter Forsyth, Richard Herri... περισσότερα »
Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 17 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Bianca Balbino, Riccardo Sibilano, Philipp Starkl, Thomas Marichal, Nicolas Gaudenzio, Hajime Karasuyama, Pierre Bruhns, Mindy Tsai, Laurent L. Reber, Stephen J. Galli BackgroundConflicting results have been obtained regarding roles of Fc receptors and effector cells in models of active systemic anaphylaxis (ASA). In part, this might reflect the choice of adjuvant used during sensitization, as various adjuvants might differentially influence the production of particular ant... περισσότερα »
Primary immunodeficiency diseases – genomic approaches delineate heterogeneous Mendelian disorders
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Asbjørg Stray-Pedersen, Hanne Sørmo Sorte, Pubudu Samarakoon, Tomasz Gambin, Ivan K. Chinn, Zeynep H. Coban Akdemir, Hans Christian Erichsen, Lisa R. Forbes, Shen Gu, Bo Yuan, Shalini N. Jhangiani, Donna M. Muzny, Olaug Kristin Rødningen, Ying Sheng, Sarah K. Nicholas, Lenora M. Noroski, Filiz O. Seeborg, Carla Davis, Debra Canter, Emily M. Mace, Tim Vece, Carl E. Allen, Harshal A. Abhyankar, Phil Boone, Christine R. Beck, Wojciech Krysztof Wiszniewski, Børre Fevang, Pål Au... περισσότερα »
Body fat mass distribution and interrupter resistance, fractional exhaled nitric oxide and asthma at school-age
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Herman T. den Dekker, Karen PI. Ros, Johan C. de Jongste, Irwin K. Reiss, Vincent WV. Jaddoe, Liesbeth Duijts BackgroundObesity and asthma often coexist. We hypothesized that detailed body fat distribution measures might be more strongly associated with childhood asthma than body mass index (BMI).ObjectiveWe examined the associations of total body and abdominal fat measures with respiratory resistance (Rint), fractional exhaled nitric oxide (FeNO), and the risks of wheezing... περισσότερα »
Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discussion of the diagnosis and treatment
Publication date: Available online 16 July 2016 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Zoghlami, N. Bon Mardion, F. Callonnec, D. Dehesdin, F. Proust, J.-P. Marie IntroductionSkull base meningoencephaloceles are rare congenital malformations. The two cases of transalar transsphenoidal malformation reported here differ from the classical transsphenoidal meningoencephalocele.Case reportsCase 1 was a… Continue reading Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discus... περισσότερα »
Palliative care in Africa is a complex topic. Read our latest Special Issue here – https://t.co/qNzEZ96GBV https://t.co/2AdVy369d7
Palliative care in Africa is a complex topic. Read our latest Special Issue here – https://t.co/qNzEZ96GBV https://t.co/2AdVy369d7 from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/754962688678227968 via IFTTT
Cancers, Vol. 8, Pages 69: Wnt Lipidation and Modifiers in Intestinal Carcinogenesis and Cancer
The wingless (Wnt) signaling is suggested as a fundamental hierarchical pathway in regulation of proliferation and differentiation of cells. The Wnt ligands are small proteins of about 40 kDa essentially for regulation and initiation of the Wnt activity. They are secreted proteins requiring acylation for activity in the Wnt signaling cascade and for functional interactivity… Continue reading Cancers, Vol. 8, Pages 69: Wnt Lipidation and Modifiers in Intestinal Carcinogenesis and Cancer
Findings in mice – and companion animals such as cats – are leading to clinical trials of oncolytic virotherapy: https://t.co/Yg8ylW1lZo
Findings in mice – and companion animals such as cats – are leading to clinical trials of oncolytic virotherapy: https://t.co/Yg8ylW1lZo from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/754957713218691072 via IFTTT
Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
Indoleamine 2,3-dioxygenase (IDO) expression in dendritic cells (DCs) inhibits T-cell activation and promotes T-cell differentiation into regulatory T-cells. Moreover, IDO expression promotes resistance to immunotherapies targeting immune checkpoints such as the cytotoxic T lymphocyte antigen-4 (CTLA-4). Here, a patient with metastatic melanoma pretreated with ipilimumab, an anti-CTLA-4 blocking antibody, was vaccinated with IDO-silenced DCs cotransfected… Continue reading Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO... περισσότερα »
Cancers, Vol. 8, Pages 69: Wnt Lipidation and Modifiers in Intestinal Carcinogenesis and Cancer
The wingless (Wnt) signaling is suggested as a fundamental hierarchical pathway in regulation of proliferation and differentiation of cells. The Wnt ligands are small proteins of about 40 kDa essentially for regulation and initiation of the Wnt activity. They are secreted proteins requiring acylation for activity in the Wnt signaling cascade and for functional interactivity… Continue reading Cancers, Vol. 8, Pages 69: Wnt Lipidation and Modifiers in Intestinal Carcinogenesis and Cancer
Regulation of Inflammation by Lipid Mediators in Oral Diseases
Abstract Lipid mediators (LM) of inflammation are a class of compounds derived from ω-3 and ω-6 fatty acids that play a wide role in modulating inflammatory responses. Some LM possess pro-inflammatory properties, while others possess pro-resolving characteristics, and the class switch from pro-inflammatory to pro-resolving is crucial for tissue homeostasis. In this article, we review… Continue reading Regulation of Inflammation by Lipid Mediators in Oral Diseases
Cancers, Vol. 8, Pages 69: Wnt Lipidation and Modifiers in Intestinal Carcinogenesis and Cancer
The wingless (Wnt) signaling is suggested as a fundamental hierarchical pathway in regulation of proliferation and differentiation of cells. The Wnt ligands are small proteins of about 40 kDa essentially for regulation and initiation of the Wnt activity. They are secreted proteins requiring acylation for activity in the Wnt signaling cascade and for functional interactivity… Continue reading Cancers, Vol. 8, Pages 69: Wnt Lipidation and Modifiers in Intestinal Carcinogenesis and Cancer
Contents
Publication date: August 2016 Source:Clinical Neurophysiology, Volume 127, Issue 8 from Physiology via xlomafota13 on Inoreader http://ift.tt/2a5aV6R via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29IVG1k via IFTTT
Establishing standards for neuronavigated TMS in research and clinical studies
Publication date: August 2016 Source:Clinical Neurophysiology, Volume 127, Issue 8 Author(s): Muthuraman Muthuraman, Chaitanya Venkata Chirumamilla, Sergiu Groppa from Physiology via xlomafota13 on Inoreader http://ift.tt/2a9Tjda via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2a1hCbW via IFTTT
Transalar transsphenoidal meningoencephalocele presenting in the form of recurrent meningitis: Report of two cases and discussion of the diagnosis and treatment
Publication date: Available online 16 July 2016 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Zoghlami, N. Bon Mardion, F. Callonnec, D. Dehesdin, F. Proust, J.-P. Marie IntroductionSkull base meningoencephaloceles are rare congenital malformations. The two cases of transalar transsphenoidal malformation reported here differ from the classical transsphenoidal meningoencephalocele.Case reportsCase 1 was a three-and-a-half-year-old boy and case 2 was a 36-year-old man. Both cases presented with clinical features of recurrent meningitis. Surgical... περισσότερα »
Early and late B cell developmental impairment in NFKB1 mutated CVID disease
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Vassilios Lougaris, Daniele Moratto, Manuela Baronio, Giacomo Tampella, Jos W.M. van der Meer, Raffaele Badolato, Manfred Fliegauf, Alessandro Plebani Teaser This study provides evidence for a novel role for NFKB1 in human B cell development, both in the bone marrow and in the periphery, and in particular in the expansion of CD21lo B cells, a subset of innate-like B cells associated with autoimmune phaenomena, with evident implications in clinical co... περισσότερα »
Clinical spectrum and features of activated PI3-kinase delta syndrome: a large patient cohort study
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tanya I. Coulter, Anita Chandra, Chris M. Bacon, Judith Babar, James Curtis, Nick Screaton, John R. Goodlad, George Farmer, Cathal Laurence Steele, Timothy Ronan Leahy, Rainer Doffinger, Helen Baxendale, Jolanta Bernatoniene, J.D.M. Edgar, Hilary J. Longhurst, Stephan Ehl, Carsten Speckmann, Bodo Grimbacher, Anna Sediva, Tomas Milota, Saul N. Faust, Anthony P. Williams, Grant Hayman, Zeynep Yesim Kucuk, Rosie Hague, Paul French, Richard Brooker, Peter Forsyth, Richard Herri... περισσότερα »
Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis
Publication date: Available online 17 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Bianca Balbino, Riccardo Sibilano, Philipp Starkl, Thomas Marichal, Nicolas Gaudenzio, Hajime Karasuyama, Pierre Bruhns, Mindy Tsai, Laurent L. Reber, Stephen J. Galli BackgroundConflicting results have been obtained regarding roles of Fc receptors and effector cells in models of active systemic anaphylaxis (ASA). In part, this might reflect the choice of adjuvant used during sensitization, as various adjuvants might differentially influence the production of particular ant... περισσότερα »
Primary immunodeficiency diseases – genomic approaches delineate heterogeneous Mendelian disorders
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Asbjørg Stray-Pedersen, Hanne Sørmo Sorte, Pubudu Samarakoon, Tomasz Gambin, Ivan K. Chinn, Zeynep H. Coban Akdemir, Hans Christian Erichsen, Lisa R. Forbes, Shen Gu, Bo Yuan, Shalini N. Jhangiani, Donna M. Muzny, Olaug Kristin Rødningen, Ying Sheng, Sarah K. Nicholas, Lenora M. Noroski, Filiz O. Seeborg, Carla Davis, Debra Canter, Emily M. Mace, Tim Vece, Carl E. Allen, Harshal A. Abhyankar, Phil Boone, Christine R. Beck, Wojciech Krysztof Wiszniewski, Børre Fevang, Pål Au... περισσότερα »
Body fat mass distribution and interrupter resistance, fractional exhaled nitric oxide and asthma at school-age
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Herman T. den Dekker, Karen PI. Ros, Johan C. de Jongste, Irwin K. Reiss, Vincent WV. Jaddoe, Liesbeth Duijts BackgroundObesity and asthma often coexist. We hypothesized that detailed body fat distribution measures might be more strongly associated with childhood asthma than body mass index (BMI).ObjectiveWe examined the associations of total body and abdominal fat measures with respiratory resistance (Rint), fractional exhaled nitric oxide (FeNO), and the risks of wheezing... περισσότερα »
Regulation of Inflammation by Lipid Mediators in Oral Diseases
Abstract Lipid mediators (LM) of inflammation are a class of compounds derived from *ω*-3 and *ω*-6 fatty acids that play a wide role in modulating inflammatory responses. Some LM possess pro-inflammatory properties, while others possess pro-resolving characteristics, and the class switch from pro-inflammatory to pro-resolving is crucial for tissue homeostasis. In this article, we review the major classes of LM, focusing on their biosynthesis and signaling pathways, and their role in systemic and, especially, oral health and disease. We discuss the detection of these LM in various ... περισσότερα »
Pathways Linking Health Literacy, Health Beliefs, and Cognition to Medication Adherence in Older Adults with Asthma
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tacara Soones, Jenny L. Lin, Michael S. Wolf, Rachel O'Conor, Melissa Martynenko, Juan P. Wisnivesky, Alex D. Federman BackgroundLimited health literacy is associated with low adherence to asthma controller medications among older adults.ObjectiveWe sought to describe the causal pathway linking health literacy to medication adherence by modeling asthma illness and medication beliefs as mediators.MethodsWe recruited adults age 60 and older with asthma f... περισσότερα »
Pharmacological inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Asuka Honjo, Nobuhiro Nakano, Susumu Yamazaki, Mutsuko Hara, Koichiro Uchida, Jiro Kitaura, Chiharu Nishiyama, Hideo Yagita, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu BackgroundMucosal mast cells (MMCs) play a central role in the development of symptoms associated with IgE-mediated food allergy. Recently, Notch2-mediated signaling was shown to be involved in proper MMC distribution in the intestinal tract.ObjectiveThis study aimed to clarify the mechani... περισσότερα »
Restrictive interleukin-10 induction by an innocuous Parainfluenza virus vector ameliorates nasal allergy
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Keiichi Yamanaka, Takehisa Nakanishi, Kana Isono, Chisami Hasegawa, Hiroyasu Inada, Kento Mizutani, Yoshiaki Matsushima, Karin Okada, Tomotaka Mabuchi, Makoto Kondo, Akisa Yamagiwa, Masato Kakeda, Koji Habe, Tetsuya Nosaka M, Esteban C. Gabazza, Hidetoshi Yamazaki, Hitoshi Mizutani, Mitsuo Kawano Teaser A novel therapy: Topical interleukin-10 application via non-replicating human Parainfluenza type 2 virus vector ameliorates mouse cedar pollinosis wi... περισσότερα »
Early and late B cell developmental impairment in NFKB1 mutated CVID disease
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Vassilios Lougaris, Daniele Moratto, Manuela Baronio, Giacomo Tampella, Jos W.M. van der Meer, Raffaele Badolato, Manfred Fliegauf, Alessandro Plebani Teaser This study provides evidence for a novel role for NFKB1 in human B cell development, both in the bone marrow and in the periphery, and in particular in the expansion of CD21lo B cells, a subset of innate-like B cells associated with autoimmune phaenomena, with evident implications in clinical co... περισσότερα »
Clinical spectrum and features of activated PI3-kinase delta syndrome: a large patient cohort study
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tanya I. Coulter, Anita Chandra, Chris M. Bacon, Judith Babar, James Curtis, Nick Screaton, John R. Goodlad, George Farmer, Cathal Laurence Steele, Timothy Ronan Leahy, Rainer Doffinger, Helen Baxendale, Jolanta Bernatoniene, J.D.M. Edgar, Hilary J. Longhurst, Stephan Ehl, Carsten Speckmann, Bodo Grimbacher, Anna Sediva, Tomas Milota, Saul N. Faust, Anthony P. Williams, Grant Hayman, Zeynep Yesim Kucuk, Rosie Hague, Paul French, Richard Brooker, Peter Forsyth, Richard Herri... περισσότερα »
Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis
Publication date: Available online 17 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Bianca Balbino, Riccardo Sibilano, Philipp Starkl, Thomas Marichal, Nicolas Gaudenzio, Hajime Karasuyama, Pierre Bruhns, Mindy Tsai, Laurent L. Reber, Stephen J. Galli BackgroundConflicting results have been obtained regarding roles of Fc receptors and effector cells in models of active systemic anaphylaxis (ASA). In part, this might reflect the choice of adjuvant used during sensitization, as various adjuvants might differentially influence the production of particular ant... περισσότερα »
Primary immunodeficiency diseases – genomic approaches delineate heterogeneous Mendelian disorders
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Asbjørg Stray-Pedersen, Hanne Sørmo Sorte, Pubudu Samarakoon, Tomasz Gambin, Ivan K. Chinn, Zeynep H. Coban Akdemir, Hans Christian Erichsen, Lisa R. Forbes, Shen Gu, Bo Yuan, Shalini N. Jhangiani, Donna M. Muzny, Olaug Kristin Rødningen, Ying Sheng, Sarah K. Nicholas, Lenora M. Noroski, Filiz O. Seeborg, Carla Davis, Debra Canter, Emily M. Mace, Tim Vece, Carl E. Allen, Harshal A. Abhyankar, Phil Boone, Christine R. Beck, Wojciech Krysztof Wiszniewski, Børre Fevang, Pål Au... περισσότερα »
Body fat mass distribution and interrupter resistance, fractional exhaled nitric oxide and asthma at school-age
Publication date: Available online 16 July 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Herman T. den Dekker, Karen PI. Ros, Johan C. de Jongste, Irwin K. Reiss, Vincent WV. Jaddoe, Liesbeth Duijts BackgroundObesity and asthma often coexist. We hypothesized that detailed body fat distribution measures might be more strongly associated with childhood asthma than body mass index (BMI).ObjectiveWe examined the associations of total body and abdominal fat measures with respiratory resistance (Rint), fractional exhaled nitric oxide (FeNO), and the risks of wheezing... περισσότερα »
Contents
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
[image: alertIcon.gif] Publication date: August 2016 *Source:*Clinical Neurophysiology, Volume 127, Issue 8 from Physiology via xlomafota13 on Inoreader http://ift.tt/2a5aV6R via IFTTT
Establishing standards for neuronavigated TMS in research and clinical studies
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
[image: alertIcon.gif] Publication date: August 2016 *Source:*Clinical Neurophysiology, Volume 127, Issue 8 Author(s): Muthuraman Muthuraman, Chaitanya Venkata Chirumamilla, Sergiu Groppa from Physiology via xlomafota13 on Inoreader http://ift.tt/2a9Tjda via IFTTT
Looking at the muscle to find out what is happening in the brain
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
[image: alertIcon.gif] Publication date: August 2016 *Source:*Clinical Neurophysiology, Volume 127, Issue 8 Author(s): Guido Rubboli, Günter Krämer from Physiology via xlomafota13 on Inoreader http://ift.tt/2a5bg9P via IFTTT
Editorial Board
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
[image: alertIcon.gif] Publication date: August 2016 *Source:*Clinical Neurophysiology, Volume 127, Issue 8 from Physiology via xlomafota13 on Inoreader http://ift.tt/2a9Tchu via IFTTT
Testing brains with burst suppressions
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
[image: alertIcon.gif] Publication date: August 2016 *Source:*Clinical Neurophysiology, Volume 127, Issue 8 Author(s): Sampsa Vanhatalo from Physiology via xlomafota13 on Inoreader http://ift.tt/2a5aXvz via IFTTT
Quantitative analysis of surface electromyography: Biomarkers for convulsive seizures
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
[image: alertIcon.gif] Publication date: August 2016 *Source:*Clinical Neurophysiology, Volume 127, Issue 8 Author(s): Sándor Beniczky, Isa Conradsen, Ronit Pressler, Peter Wolf Muscle activity during seizures is in electroencephalographical (EEG) praxis often considered an irritating artefact. This article discusses ways by surface electromyography (EMG) to turn it into a valuable tool of epileptology.Muscles are in direct synaptic contact with motor neurons. Therefore, EMG signals provide direct information about the electric activity in the motor cortex. Qualitative analysis of EM... περισσότερα »
Remodeling of cortical activity for motor control following upper limb loss
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
[image: alertIcon.gif] Publication date: Available online 16 July 2016 *Source:*Clinical Neurophysiology Author(s): Laura Williams, Nikta Pirouz, J.C. Mizelle, William Cusack, Rob Kistenberg, Lewis A. Wheaton ObjectiveUpper extremity loss presents immediate and lasting challenges for motor control. While sensory and motor representations of the amputated limb undergo plasticity to adjacent areas of the sensorimotor homunculus, it remains unclear whether laterality of motor-related activity is affected by neural reorganization following amputation.MethodsUsing electroencephalography,... περισσότερα »
Chronic pain, quality of life, and functional impairment after surgery due to small bowel obstruction
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
World Journal of Surgery from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a53MDP via IFTTT
Low-FODMAP rye bread vs. regular rye bread to relieve the symptoms of irritable bowel syndrome
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Alimentary Pharmacology and Therapeutics from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a9N6Ob via IFTTT
Acute pancreatitis: A comparison of intervention rates precipitated by early vs guideline CT scan timing
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Clinical Radiology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a53TPI via IFTTT
Chronic hepatitis C virus infection and the risk for diabetes: A community-based prospective study
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Liver International from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a9N1do via IFTTT
Genetic biomarkers associated with anti-TNF treatment response in inflammatory bowel diseases
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Alimentary Pharmacology and Therapeutics from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a53xIJ via IFTTT
Anti-envelope antibody responses in individuals at high risk of hepatitis C virus who resist infection
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Journal of Viral Hepatitis from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a9NuMT via IFTTT
Gallstones and bariatric surgery: To treat or not to treat?
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
World Journal of Surgery from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a54j8w via IFTTT
A randomized phase II Study of FOLFOX With or Without the MET inhibitor onartuzumab in advanced adenocarcinoma of the stomach and gastroesophageal junction
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
The Oncologist from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a9NxYV via IFTTT
Gastric bypass procedure for type 2 diabetes patients with BMI <28 kg/m<sup>2</sup>
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Surgical Endoscopy from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a53RY6 via IFTTT
Nucleic acid polymers: Broad spectrum antiviral activity, antiviral mechanisms and optimization for the treatment of hepatitis B and hepatitis D infection
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Antiviral Research from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a9NpIY via IFTTT
Current status of preoperative oesophago-gastro-duodenoscopy (OGD) in bariatric NHS units--a BOMSS survey
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Obesity Surgery from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a53EnE via IFTTT
