Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τρίτη 10 Μαΐου 2016

OtoRhinoLaryngology & Medicine,New Articles,May 10th,2016,a



OtoRhinoLaryngology - Alexandros G. Sfakianakis
Minimally invasive intraoral condylectomy
 
: proof of concept reportvia Oral and Maxillofacial SurgeryPublication date: Available online 28 April 2016Source:International Journal of Oral and Maxillofacial SurgeryAuthor(s): F. Hernández-Alfaro, I. Méndez-Manjón, A. Valls-Ontañón, R. Guijarro-MartínezA significant proportion of facial asymmetry...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Temporomandibular disorders and obesity
 
Association between via ScienceDirect Publication: Journal of Cranio-Maxillofacial SurgeryPublication date: Available online 27 April 2016Source:Journal of Cranio-Maxillofacial SurgeryAuthor(s): Eunmi Rhim, Kyungdo Han, Kyoung-In YunPsychological stress can induce altered eating patterns, and studies...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Cleft sidedness and congenitally missing teeth in patients with cleft lip and palate patients
 
Cleft sidedness and congenitally missing teeth in patients with cleft lip and palate patients: The aim of this study was to investigate the prevalence of cleft sidedness, and the number of congenitally missing teeth in regard to cleft type and gender.AbstractBackgroundThe aim of this study was to investigate...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Best Masking Sound For Tinnitus
 
Best Masking Sound For Tinnitus: While tinnitus is an internal sound that doesn’t have a matching exterior source, sufferers can often find relief through external noise used to mask the sound constantly in their heads. Sound therapy is often used in conjunction with other therapies like neuromodulation...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
The acute physiological stress response to an emergency alarm and mobilization during the day and at night
 
The acute physiological stress response to an emergency alarm and mobilization during the day and at night: Sarah J Hall, Brad Aisbett, Jamie L Tait, Anne I Turner, Sally A Ferguson, Luana C MainNoise and Health 2016 18(82):150-156The purpose of this study was to investigate the acute physiological stress...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Exposures to road traffic, noise, and air pollution as risk factors for type 2 diabetes
 
: A feasibility study in Bulgaria: Angel M Dzhambov, Donka D DimitrovaNoise and Health 2016 18(82):133-142Type 2 diabetes mellitus (T2DM) is a growing public health problem in Bulgaria. While individual and lifestyle determinants have been researched; till date there has been no study on environmental...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Moderators of noise-induced cognitive change
 
 in healthy adults: Bernice AL Wright, Emmanuelle R Peters, Ulrich Ettinger, Elizabeth Kuipers, Veena KumariNoise and Health 2016 18(82):117-132Environmental noise causes cognitive impairment, particularly in executive function and episodic memory domains, in healthy populations. However, the possible...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Lack of contralateral suppression in TEOAEs in multiple chemical sensitivity
 
: a clinical correlation study: Alessandro Micarelli, Andrea Viziano, Giuseppe Genovesi, Ernesto Bruno, Fabrizio Ottaviani, Marco AlessandriniNoise and Health 2016 18(82):143-149Multiple chemical sensitivity (MCS) is a chronic disorder characterized by a variety of symptoms associated with the exposure...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Hearing loss in the Navy
 
Hearing loss in the Royal Norwegian Navy: A longitudinal study: Kaja Irgens-Hansen, Valborg Baste, Magne Bratveit, Ola Lind, Vilhelm F Koefoed, Bente E MoenNoise and Health 2016 18(82):157-165The aims of this longitudinal study were to investigate a significant threshold shift (STS) among personnel working...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Compensation for a lip-tube perturbation in 4-year-olds: Articulatory, acoustic, and perceptual data analyzed in comparison with adults
 
Compensation for a lip-tube perturbation in 4-year-olds: Articulatory, acoustic, and perceptual data analyzed in comparison with adults: The nature of the speech goal in children was investigated in a study of compensation strategies for a lip-tube perturbation. Acoustic, articulatory, and perceptual...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Influence of voxelization on finite difference time domain simulations of head-related transfer functions
 
Influence of voxelization on finite difference time domain simulations of head-related transfer functions: The scattering around the human pinna that is captured by the Head-Related Transfer Functions (HRTFs) is a complex problem that creates uncertainties in both acoustical measurements and simulations....
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Durations required to distinguish noise and tone
 
Effects of noise bandwidth and frequencya): Perceptual audio coders exploit the masking properties of the human auditory system to reduce the bit rate in audio recording and transmission systems; it is intended that the quantization noise is just masked by the audio signal. The effectiveness of the audio...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Best Masking Sound For Tinnitus
 
While tinnitus is an internal sound that doesn't have a matching exterior source, sufferers can often find relief through external noise used to mask the sound constantly in their heads. Sound therapy is often used in conjunction with other therapies like neuromodulation and habituation. Living with...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Classification, diagnostic criteria and management of benign paroxysmal positional vertigo
 
Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vertigo and the posterior and/or lateral semicircular canals are usually affected. BPPV is characterized by brief attacks of rotatory vertigo associated with positional and/or positioning nystagmus, which are elicited by specific...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Schwellungen der Glandulae submandibularis und parotis
 
Zusammenfassung Eine Vielzahl von lokalen oder systemischen Erkrankungen kann zu Schwellungen einer oder mehrerer Kopfspeicheldrüsen führen. Neben kongenitalen zystischen oder vaskulären Fehlbildungen können sowohl entzündliche als auch tumoröse Prozesse differenzialdiagnostisch abgegrenzt werden. Auch...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Effects of orthographic consistency and homophone density on Chinese spoken word recognition
 
Publication date: June–July 2016Source:Brain and Language, Volumes 157–158 Author(s): Wei-Fan Chen, Pei-Chun Chao, Ya-Ning Chang, Chun-Hsien Hsu, Chia-Ying Lee Studies of alphabetic language have shown that orthographic knowledge influences phonological processing during spoken word recognition....
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Athlete or athletic? Limited differential brain activation in person descriptions using nouns or adjectives
 
Publication date: August 2016Source:Brain and Language, Volume 159 Author(s): Laurens Van der Cruyssen, Ceylan Özdem, Tessa Haesevoets, Marie Vandekerckhove, Frank Van Overwalle Do differences between the syntactic categories of nouns and adjectives for describing persons translate into different...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
The acute physiological stress response to an emergency alarm and mobilization during the day and at night
 
Sarah J Hall, Brad Aisbett, Jamie L Tait, Anne I Turner, Sally A Ferguson, Luana C Main Noise and Health 2016 18(82):150-156 The purpose of this study was to investigate the acute physiological stress response to an emergency alarm and mobilization during the day and at night. Sixteen healthy males...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Exposures to road traffic, noise, and air pollution as risk factors for type 2 diabetes: A feasibility study in Bulgaria
 
Angel M Dzhambov, Donka D Dimitrova Noise and Health 2016 18(82):133-142 Type 2 diabetes mellitus (T2DM) is a growing public health problem in Bulgaria. While individual and lifestyle determinants have been researched; till date there has been no study on environmental risks such as road traffic, noise,...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Moderators of noise-induced cognitive change in healthy adults
 
Bernice AL Wright, Emmanuelle R Peters, Ulrich Ettinger, Elizabeth Kuipers, Veena Kumari Noise and Health 2016 18(82):117-132 Environmental noise causes cognitive impairment, particularly in executive function and episodic memory domains, in healthy populations. However, the possible moderating influences...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Lack of contralateral suppression in transient-evoked otoacoustic emissions in multiple chemical sensitivity: a clinical correlation study
 
Alessandro Micarelli, Andrea Viziano, Giuseppe Genovesi, Ernesto Bruno, Fabrizio Ottaviani, Marco Alessandrini Noise and Health 2016 18(82):143-149 Multiple chemical sensitivity (MCS) is a chronic disorder characterized by a variety of symptoms associated with the exposure to chemicals at a concentration...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Hearing loss in the Royal Norwegian Navy: A longitudinal study
 
Kaja Irgens-Hansen, Valborg Baste, Magne Bratveit, Ola Lind, Vilh



Orbital Metastasis of Undifferentiated/Anaplastic Thyroid Carcinoma.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 4 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Orbital Metastasis of Undifferentiated/Anaplastic Thyroid Carcinoma.* Ophthal Plast Reconstr Surg. 2015 Sep-Oct;31(5):e120-3 Authors: Gupta D, Chappell M, Tailor TD, Keene CD, Moe K, Jian-Amadi A, Chang SH Abstract A 52-year-old woman presented with decreased vision, diplopia, esotropia, proptosis, and right orbital pain. Clinical examination was suspicious for an orbital mass and additionally revealed a thyroid gland mass. Imaging studies showed an enhancing mass within the right lateral rectus muscle and a hete... περισσότερα »

CRIBRIFORM-MORULAR VARIANT OF THYROID CANCER - A RED FLAG FOR FAMILIAL ADENOMATOUS POLYPOSIS.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 4 δευτερόλεπτα
*CRIBRIFORM-MORULAR VARIANT OF THYROID CANCER - A RED FLAG FOR FAMILIAL ADENOMATOUS POLYPOSIS.* J La State Med Soc. 2015 May-Jun;167(3):148-149 Authors: Nair R, Sun GE Abstract Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome characterized by the development of colorectal adenomas which may be caused by mutations of the Adenomatosis polyposis colon gene. Patients with FAP are at risk for several additional intestinal malignancies including well-differentiated thyroid cancer, childhood hepatoblastoma, and central nervous system tumors. Cribriform-morular vari... περισσότερα »

Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 4 δευτερόλεπτα
*Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis.* J Clin Invest. 2016 May 9; Authors: Di Girolamo D, Ambrosio R, De Stefano MA, Mancino G, Porcelli T, Luongo C, Di Cicco E, Scalia G, Vecchio LD, Colao A, Dlugosz AA, Missero C, Salvatore D, Dentice M Abstract The thyroid hormone-inactivating (TH-inactivating) enzyme type 3 iodothyronine deiodinase (D3) is an oncofetal protein that is rarely expressed in adult life but has been shown to be reactivated in the context of proliferation and neoplasms. D3 terminates TH a...περισσότερα »

Methylation Markers for Early Detection and Differentiation of Follicular Thyroid Cancer Subtypes.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 4 δευτερόλεπτα
*Methylation Markers for Early Detection and Differentiation of Follicular Thyroid Cancer Subtypes.* Cancer Clin Oncol. 2015 Nov;4(2):1-12 Authors: Stephen JK, Chen KM, Merritt J, Chitale D, Divine G, Worsham MJ Abstract Thyroid cancer has the fastest rising incidence rates and is the fifth most common cancer in women. There are four main types of which the papillary and follicular types together account for >90%, followed by medullary cancers (3%-5%) and anaplastic carcinomas (<3%). For individuals who present with early stage disease of papillary and follicular cancers, there a...περισσότερα »

ApolipoproteinL1 is expressed in papillary thyroid carcinomas.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 4 δευτερόλεπτα
*ApolipoproteinL1 is expressed in papillary thyroid carcinomas.* Pathol Res Pract. 2016 Apr 24; Authors: Chidiac M, Fayyad-Kazan M, Daher J, Poelvoorde P, Bar I, Maenhaut C, Delrée P, Badran B, Vanhamme L Abstract The apolipoprotein L (apoL) family has not yet been ascribed any definite patho-physiological function although the conserved BH3 protein domain suggests a role in programmed cell death. As repression of the regular apoptotic program is considered a hallmark of tumor progression, we investigated apoL expression in cancer. We show that the levels of one member of the fam...περισσότερα »

Systemic cobalt toxicity from total hip arthroplasties: review of a rare condition Part 1 - history, mechanism, measurements, and pathophysiology.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 4 δευτερόλεπτα
Related Articles *Systemic cobalt toxicity from total hip arthroplasties: review of a rare condition Part 1 - history, mechanism, measurements, and pathophysiology.* Bone Joint J. 2016 Jan;98-B(1):6-13 Authors: Cheung AC, Banerjee S, Cherian JJ, Wong F, Butany J, Gilbert C, Overgaard C, Syed K, Zywiel MG, Jacobs JJ, Mont MA Abstract UNLABELLED: Recently, the use of metal-on-metal articulations in total hip arthroplasty (THA) has led to an increase in adverse events owing to local soft-tissue reactions from metal ions and wear debris. While the majority of these implants perform w... περισσότερα »

Case Report: Nodule Development From Subcapsular Aldosterone-Producing Cell Clusters Causes Hyperaldosteronism.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 4 δευτερόλεπτα
Related Articles *Case Report: Nodule Development From Subcapsular Aldosterone-Producing Cell Clusters Causes Hyperaldosteronism.* J Clin Endocrinol Metab. 2016 Jan;101(1):6-9 Authors: Nishimoto K, Seki T, Kurihara I, Yokota K, Omura M, Nishikawa T, Shibata H, Kosaka T, Oya M, Suematsu M, Mukai K Abstract CONTEXT: We previously reported that the human adrenal cortex remodels to form subcapsular aldosterone-producing cell clusters (APCCs). Some APCCs were recently found to carry aldosterone-producing adenoma (APA)-associated somatic mutations in ion channel/pump genes, which impli... περισσότερα »

Letter to the editor regarding association of vascular invasion with mortality in follicular thyroid carcinoma.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 4 δευτερόλεπτα
Related Articles *Letter to the editor regarding association of vascular invasion with mortality in follicular thyroid carcinoma.* Head Neck. 2016 Jan;38(1):158 Authors: Rajan S, Kumar C PMID: 26348092 [PubMed - indexed for MEDLINE] from pubmed: thyroid cancer http://ift.tt/23EdDmu via IFTTT

Reply to Letter to the Editor regarding association of vascular invasion with increased mortality in patients with minimally invasive follicular thyroid carcinoma but not widely invasive follicular thyroid carcinoma.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 4 δευτερόλεπτα
Related Articles *Reply to Letter to the Editor regarding association of vascular invasion with increased mortality in patients with minimally invasive follicular thyroid carcinoma but not widely invasive follicular thyroid carcinoma.* Head Neck. 2016 Jan;38(1):159 Authors: Kim HJ, Chung JH PMID: 26347961 [PubMed - indexed for MEDLINE] from pubmed: thyroid cancer http://ift.tt/24JBVkV via IFTTT

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
Related Articles *Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.* Nat Commun. 2015;6:8013 Authors: Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, Cavett V, Nowak J, Chalmers MJ, Marciano DP, Kamenecka TM, Shulman AI, Rance M, Griffin PR, Bruning JB, Nettles KW Abstract A subset of nuclear receptors (NRs) function as obligate heterodimers with retinoid X receptor (RXR), allowing integration of ligand-dependent signals across the dimer interface via an unknown structural mechanism. Using nuclear magnetic resonance (NMR) spec...περισσότερα »

PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
Related Articles *PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation.* Nat Commun. 2015;6:7882 Authors: Iansante V, Choy PM, Fung SW, Liu Y, Chai JG, Dyson J, Del Rio A, D'Santos C, Williams R, Chokshi S, Anders RA, Bubici C, Papa S Abstract Most tumour cells use aerobic glycolysis (the Warburg effect) to support anabolic growth and evade apoptosis. Intriguingly, the molecular mechanisms that link the Warburg effect with the suppression of apoptosis are not well understood. In this study, using loss-of-f... περισσότερα »

Reply to Letter to the Editor regarding association of vascular invasion with increased mortality in patients with minimally invasive follicular thyroid carcinoma but not widely invasive follicular thyroid carcinoma.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Related Articles *Reply to Letter to the Editor regarding association of vascular invasion with increased mortality in patients with minimally invasive follicular thyroid carcinoma but not widely invasive follicular thyroid carcinoma.* Head Neck. 2016 Jan;38(1):159 Authors: Kim HJ, Chung JH PMID: 26347961 [PubMed - indexed for MEDLINE] from pubmed: thyroid cancer http://ift.tt/24JBVkV via IFTTT

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Related Articles *Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.* Nat Commun. 2015;6:8013 Authors: Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, Cavett V, Nowak J, Chalmers MJ, Marciano DP, Kamenecka TM, Shulman AI, Rance M, Griffin PR, Bruning JB, Nettles KW Abstract A subset of nuclear receptors (NRs) function as obligate heterodimers with retinoid X receptor (RXR), allowing integration of ligand-dependent signals across the dimer interface via an unknown structural mechanism. Using nuclear magnetic resonance (NMR) spec...περισσότερα »

PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Related Articles *PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation.* Nat Commun. 2015;6:7882 Authors: Iansante V, Choy PM, Fung SW, Liu Y, Chai JG, Dyson J, Del Rio A, D'Santos C, Williams R, Chokshi S, Anders RA, Bubici C, Papa S Abstract Most tumour cells use aerobic glycolysis (the Warburg effect) to support anabolic growth and evade apoptosis. Intriguingly, the molecular mechanisms that link the Warburg effect with the suppression of apoptosis are not well understood. In this study, using loss-of-f... περισσότερα »

The tumor-suppressive role of BATF2 in esophageal squamous cell carcinoma.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 6 δευτερόλεπτα
Related Articles *The tumor-suppressive role of BATF2 in esophageal squamous cell carcinoma.* Oncol Rep. 2015 Sep;34(3):1353-60 Authors: Han T, Wang Z, Yang Y, Shu T, Li W, Liu D, Li P, Qi R, Ren Y, Li L, Liu H, Zhang S, Zhang L Abstract BATF2 has been found to be decreased in a variety of human malignancies, while its clinical significance and functional roles in esophageal squamous cell carcinoma (ESCC) remain unknown. Herein, the aim of this study was to investigate the expression pattern and to explore the potential functions of BATF2 in ESCC tissues and cell lines. BATF2 mRN... περισσότερα »

Prevalent low-grade dysplasia: the strongest predictor of malignant progression in Barrett's columnar-lined oesophagus.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 6 δευτερόλεπτα
Related Articles *Prevalent low-grade dysplasia: the strongest predictor of malignant progression in Barrett's columnar-lined oesophagus.* Gut. 2016 Feb;65(2):360-1 Authors: Moyes LH, Oien KA, Foulis AK, Fullarton GM, Going JJ PMID: 26085438 [PubMed - indexed for MEDLINE] from pubmed: esophageal cancer http://ift.tt/1ZAhxf6 via IFTTT

Fluoroscopically guided large balloon dilatation for treating congenital esophageal stenosis in children.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 6 δευτερόλεπτα
Related Articles *Fluoroscopically guided large balloon dilatation for treating congenital esophageal stenosis in children.* Jpn J Radiol. 2015 Jul;33(7):418-23 Authors: Hu HT, Shin JH, Kim JH, Jang JK, Park JH, Kim TH, Nam DH, Song HY Abstract PURPOSE: We aimed to evaluate the safety and clinical effectiveness of fluoroscopically guided large balloon dilatation for treating congenital esophageal stenosis in children. METHODS: Our study included seven children (mean age 4.0 years) who underwent a total of ten balloon dilatation sessions. The initial balloon diameters were 10-15 m... περισσότερα »

Carcinoma of the superior mediastinal segment of the esophagus; a technique for resection with restoration of continuity of the alimentary canal.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 6 δευτερόλεπτα
Related Articles *Carcinoma of the superior mediastinal segment of the esophagus; a technique for resection with restoration of continuity of the alimentary canal.* Surgery. 1948 Dec;24(6):929-38 Authors: SWEET RH PMID: 18099796 [PubMed - indexed for MEDLINE] from pubmed: esophageal cancer http://ift.tt/1T34WNH via IFTTT

Digital chromoendoscopy utilization in clinical practice: A survey of gastroenterologists in Connecticut.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 6 δευτερόλεπτα
*Digital chromoendoscopy utilization in clinical practice: A survey of gastroenterologists in Connecticut.* World J Gastrointest Pharmacol Ther. 2016 May 6;7(2):268-73 Authors: Langberg KM, Parikh ND, Deng Y, Ciarlegio M, Laine L, Aslanian HR Abstract AIM: To use a survey to characterize and identify potential barriers to the use of digital chromoendoscopy (DC) by practicing gastroenterologists. METHODS: An anonymous, internet-based survey was sent to gastroenterologists in Connecticut who were members of one of three national gastrointestinal organizations. The survey collected de... περισσότερα »

Update on management of Barrett's esophagus.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 6 δευτερόλεπτα
*Update on management of Barrett's esophagus.* World J Gastrointest Pharmacol Ther. 2016 May 6;7(2):227-34 Authors: Macías-García F, Domínguez-Muñoz JE Abstract Barrett's esophagus (BE) is a common condition that develops as a consequence of gastroesophageal reflux disease. The significance of Barrett's metaplasia is that predisposes to cancer development. This article provides a current evidence-based review for the management of BE and related early neoplasia. Controversial issues that impact the management of patients with BE, including definition, screening, clinical aspects,...περισσότερα »

Diaphragmatic hernia following oesophagectomy for oesophageal cancer - Are we too radical?

Alexandros G. SfakianakisστοThe OesophagusΠριν από 8 δευτερόλεπτα
*Diaphragmatic hernia following oesophagectomy for oesophageal cancer - Are we too radical?* Ann Med Surg (Lond). 2016 Mar;6:30-5 Authors: Argenti F, Luhmann A, Dolan R, Wilson M, Podda M, Patil P, Shimi S, Alijani A Abstract BACKGROUND: Diaphragmatic herniation (DH) of abdominal contents into the thorax after oesophageal resection is a recognised and serious complication of surgery. While differences in pressure between the abdominal and thoracic cavities are important, the size of the hiatal defect is something that can be influenced surgically. As with all oncological surgery,...περισσότερα »

AKAP4 mediated tumor malignancy in esophageal cancer.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 8 δευτερόλεπτα
*AKAP4 mediated tumor malignancy in esophageal cancer.* Am J Transl Res. 2016;8(2):597-605 Authors: Li S, Qin X, Li Y, Guo A, Ma L, Jiao F, Chai S Abstract AKAP4 as a new Cancer/Testis (CT) antigen is expressed not only in human germ cells, but also expressed in various tumor cells. AKAP4 is correlated with tumor malignancy; however, the role of AKAP4 in esophageal cancer remains unknown. Here we explored the function of AKAP4 in esophageal cancer. We found that AKAP4 mRNA and protein levels were up-regulated in the esophageal cancer tissues compared to normal control. In KYSE150 ... περισσότερα »

Post-ablation surveillance in Barrett's esophagus: A review of the literature.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 8 δευτερόλεπτα
*Post-ablation surveillance in Barrett's esophagus: A review of the literature.* World J Gastroenterol. 2016 May 7;22(17):4297-306 Authors: Stier MW, Konda VJ, Hart J, Waxman I Abstract Barrett's esophagus (BE) is a pre-malignant condition affecting up to 15% of patients with gastroesophageal reflux disease. Neoplastic Barrett's mucosa is defined as harboring high grade dysplasia or intra-mucosal cancer, and carries a high risk of progression to esophageal adenocarcinoma. The rising incidence of Barrett's lesions along with the high morbidity of surgical approaches has led to the... περισσότερα »

Minimally Invasive Versus Open Esophagectomy for Esophageal Cancer: A Population-Based Analysis.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 8 δευτερόλεπτα
*Minimally Invasive Versus Open Esophagectomy for Esophageal Cancer: A Population-Based Analysis.* Ann Thorac Surg. 2016 May 3; Authors: Yerokun BA, Sun Z, Jeffrey Yang CF, Gulack BC, Speicher PJ, Adam MA, D'Amico TA, Onaitis MW, Harpole DH, Berry MF, Hartwig MG Abstract BACKGROUND: The objective of this study was to evaluate outcomes of minimally invasive approaches to esophagectomy using population-level data. METHODS: Multivariable regression modeling was used to determine predictors associated with the use of minimally invasive approaches for patients in the National Cancer Da... περισσότερα »

Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 8 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.* Ann Surg. 2016 Feb;263(2):251-7 Authors: Maret-Ouda J, Konings P, Lagergren J, Brusselaers N Abstract OBJECTIVE: To investigate the preventive effect of antireflux surgery against esophageal adenocarcinoma (EAC) compared with medical treatment of gastroesophageal reflux disease (GERD) and to the background population. BACKGROUND: GERD is causally associated with EAC. Effective symptomatic treatment can be achieved wit... περισσότερα »

Recurrence after hepatic resection in colorectal cancer liver metastasis -Review article-.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 8 δευτερόλεπτα
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Recurrence after hepatic resection in colorectal cancer liver metastasis -Review article-.* J Med Life. 2015;8 Spec Issue:12-4 Authors: Lintoiu-Ursut B, Tulin A, Constantinoiu S Abstract The outcomes and management of colorectal liver metastasis have undergone many changes. The incidence of recurrence after liver resection for hepatic metastasis remains very high. Liver resection, which provides the only curative treatment, is believed to have improved the long-term outcome of these patients. However, the management and outc... περισσότερα »

High Expression of LAMP3 Is a Novel Biomarker of Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 8 δευτερόλεπτα
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *High Expression of LAMP3 Is a Novel Biomarker of Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma.* Int J Mol Sci. 2015;16(8):17655-67 Authors: Liao X, Chen Y, Liu D, Li F, Li X, Jia W Abstract Lysosomal-associated membrane protein 3 (LAMP3), identified as a molecular marker of mature dendritic cells, is one of the LAMP family members. Its expression was induced by hypoxia, and was associated with hypoxia mediated metastasis in breast and cervical cancers. However, epithelial expression of LAMP3 and its pro... περισσότερα »

The tumor-suppressive role of BATF2 in esophageal squamous cell carcinoma.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 8 δευτερόλεπτα
Related Articles *The tumor-suppressive role of BATF2 in esophageal squamous cell carcinoma.* Oncol Rep. 2015 Sep;34(3):1353-60 Authors: Han T, Wang Z, Yang Y, Shu T, Li W, Liu D, Li P, Qi R, Ren Y, Li L, Liu H, Zhang S, Zhang L Abstract BATF2 has been found to be decreased in a variety of human malignancies, while its clinical significance and functional roles in esophageal squamous cell carcinoma (ESCC) remain unknown. Herein, the aim of this study was to investigate the expression pattern and to explore the potential functions of BATF2 in ESCC tissues and cell lines. BATF2 mRN... περισσότερα »

Prevalent low-grade dysplasia: the strongest predictor of malignant progression in Barrett's columnar-lined oesophagus.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 8 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] [image: http:--highwire.stanford.edu-icons-exter] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Prevalent low-grade dysplasia: the strongest predictor of malignant progression in Barrett's columnar-lined oesophagus.* Gut. 2016 Feb;65(2):360-1 Authors: Moyes LH, Oien KA, Foulis AK, Fullarton GM, Going JJ PMID: 26085438 [PubMed - indexed for MEDLINE] from #Esophageal Cancer via xlomafota13 on Inoreader http://ift.tt/1ZAhxf6 via IFTTT

Correction: Ambient temperature deposition of gallium nitride/gallium oxynitride from a deep eutectic electrolyte, under potential control

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 10 δευτερόλεπτα
*Chem. Commun.*, 2016, Advance Article *DOI*: 10.1039/C6CC90214F, Correction [image: Open Access] Open Access [image: Creative Commons Licence] This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Sujoy Sarkar, S. Sampath To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1UPkGZh via IFTTT

Synthesis, structure and reactivity of an imine-stabilized carboranylphosphorus(I) compound

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 10 δευτερόλεπτα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC03368G, Communication Tek Long Chan, Zuowei Xie A new imine-stabilized carboranyl-phosphinidene has been synthesized and structurally characterized. DFT studies suggest that the imine moiety provides an electron pair to stabilize carboranyl-phosphinidene. On the other hand, the sterically... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1T35OSg via IFTTT

Angiosarcoma of the Eyelid With Superimposed Enterobacter Infection

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 10 δευτερόλεπτα
Angiosarcoma of the Eyelid With Superimposed Enterobacter Infection: [image: image]Angiosarcoma is a rare, aggressive, malignant endothelial neoplasm with a variable clinical presentation. The authors describe a case of angiosarcoma involving the eyelid that was complicated by a superimposed Enterobacter infection. Following positive cultures for E. aerogenes and multiple biopsies suspicious but not definitive for angiosarcoma, a final biopsy was consistent with angiosarcoma.

Simultaneous Stabilization and Multimerization of a Peptide α-Helix by Stapling Polymerization

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 10 δευτερόλεπτα
Maintaining specific conformations of peptide ligands is crucial for improving the efficacy of biological interactions. Here, a one-pot polymerization strategy for stabilizing the α-helical conformation of peptides while simultaneously constructing multimeric ligands is presented. The new method, termed stapling polymerization, uses radical polymerization between acryloylated peptide side chains and vinylic monomers. Studies with model peptides indicate that *i*, *i+7* crosslinking is effective for the helix stabilization, whereas *i*, *i+4* crosslinking is not. The stapling poly... περισσότερα »

Corrigendum to “Magnesium Lithospermate B, an Active Extract of Salvia miltiorrhiza, Mediates sGC/cGMP/PKG Translocation in Experimental Vasospasm”

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 10 δευτερόλεπτα
from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/27a7CTh via IFTTT

Synthesis of isoalkanes over core (Fe-Zn-Zr)-shell (zeolite) catalyst from CO2 hydrogenation

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 10 δευτερόλεπτα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC01965J, Communication Xiaoxing Wang, Guohui Yang, Junfeng Zhang, Shuyao Chen, Yingquan Wu, Qingde Zhang, Junwei Wang, Yizhuo Han, Yisheng Tan A kind of core-shell catalyst with Fe-Zn-Zr as core and zeolite (HZSM-5, Hbeta, and HY) as shell was synthesized by a simple cladding method. The catalyst has an obvious confinement... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/21RJBfR via IFTTT

Incision and Curettage Versus Steroid Injection for the Treatment of Chalazia: A Meta-Analysis

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 10 δευτερόλεπτα
Incision and Curettage Versus Steroid Injection for the Treatment of Chalazia: A Meta-Analysis: [image: image]Purpose: To compare the efficacy of the chalazia treatment modalities of incision and curettage (I&C) and intralesional steroid injections (SI). Methods: Full publications of randomized controlled trials that compared I&C with SI were identified. Aggregated success rate, weighted summary proportions, and weighted pooled relative risk for success were calculated for each method. Results: Data were extracted from 8 publications that met these criteria, between 1984 and 2013. ...περισσότερα »

Design and Fabrication of Clustered Rugged ZnO Nanotube Films with Condensate Microdrop Self-Propelling Function

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 10 δευτερόλεπτα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC02822E, Communication Ying Chen, zhihong Jing We design and fabricate a type of condensate microdrop self-propelling (CMDSP) clustered rugged nanotube films, which are achieved by two-step electrodeposition and low-surface-energy silane modification. This work offers an avenue... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/21RJBfL via IFTTT

Thoracic endovascular aortic repair for blunt thoracic aortic injuries in complex aortic arch vessels anatomies.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Thoracic endovascular aortic repair for blunt thoracic aortic injuries in complex aortic arch vessels anatomies.* Ann Vasc Surg. 2015 Aug;29(6):1320.e11-5 Authors: Piffaretti G, Carrafiello G, Ierardi AM, Mariscalco G, Macchi E, Castelli P, Tozzi M, Franchin M Abstract The aim of this study is to report the use of thoracic endovascular aortic repair (TEVAR) in blunt thoracic aortic injuries (BTAIs) presenting with complex anatomies of the aortic arch vessels. Two patients were admitted to our hospital for the man... περισσότερα »

Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis.* Respir Care. 2015 Feb;60(2):244-50 Authors: Lee AL, Button BM, Denehy L, Roberts S, Bamford T, Mu FT, Mifsud N, Stirling R, Wilson JW Abstract BACKGROUND: Acid gastroesophageal reflux is a common problem in non-cystic fibrosis bronchiectasis and COPD. Invasive methods are used to diagnose gastroesophageal reflux, but the ability to detect pulmonary microaspiration of gastric contents using this me... περισσότερα »

Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.* Clin Gastroenterol Hepatol. 2015 Sep;13(9):1560-6 Authors: Francis DO, Vaezi MF Abstract Although laryngopharyngeal reflux, also known as extraesophageal reflux (EER), was codified more than 25 years ago, it has not been characterized fully. There is no sensitive and specific diagnostic test, and its symptoms often are nonspecific and overlap with those of other conditions commonly seen in primary care and specialist practices. Otolaryngol... περισσότερα »

Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.* Ann Surg. 2016 Feb;263(2):251-7 Authors: Maret-Ouda J, Konings P, Lagergren J, Brusselaers N Abstract OBJECTIVE: To investigate the preventive effect of antireflux surgery against esophageal adenocarcinoma (EAC) compared with medical treatment of gastroesophageal reflux disease (GERD) and to the background population. BACKGROUND: GERD is causally associated with EAC. Effective symptomatic treatment can be achieved with... περισσότερα »

Thoracic endovascular aortic repair for blunt thoracic aortic injuries in complex aortic arch vessels anatomies.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Thoracic endovascular aortic repair for blunt thoracic aortic injuries in complex aortic arch vessels anatomies.* Ann Vasc Surg. 2015 Aug;29(6):1320.e11-5 Authors: Piffaretti G, Carrafiello G, Ierardi AM, Mariscalco G, Macchi E, Castelli P, Tozzi M, Franchin M Abstract The aim of this study is to report the use of thoracic endovascular aortic repair (TEVAR) in blunt thoracic aortic injuries (BTAIs) presenting with complex anatomies of the aortic arch vessels. Two patients were admitted to our hospital for the mana... περισσότερα »

Investigation of Dysphagia After Antireflux Surgery by High-resolution Manometry: Impact of Multiple Water Swallows and a Solid Test Meal on Diagnosis, Management, and Clinical Outcome.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Investigation of Dysphagia After Antireflux Surgery by High-resolution Manometry: Impact of Multiple Water Swallows and a Solid Test Meal on Diagnosis, Management, and Clinical Outcome.* Clin Gastroenterol Hepatol. 2015 Sep;13(9):1575-83 Authors: Wang YT, Tai LF, Yazaki E, Jafari J, Sweis R, Tucker E, Knowles K, Wright J, Ahmad S, Kasi M, Hamlett K, Fox MR, Sifrim D Abstract BACKGROUND & AIMS: Management of patients with dysphagia, regurgitation, and related symptoms after antireflux surgery is challenging. This p... περισσότερα »

Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis.* Respir Care. 2015 Feb;60(2):244-50 Authors: Lee AL, Button BM, Denehy L, Roberts S, Bamford T, Mu FT, Mifsud N, Stirling R, Wilson JW Abstract BACKGROUND: Acid gastroesophageal reflux is a common problem in non-cystic fibrosis bronchiectasis and COPD. Invasive methods are used to diagnose gastroesophageal reflux, but the ability to detect pulmonary microaspiration of gastric contents using this met... περισσότερα »

Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.* Clin Gastroenterol Hepatol. 2015 Sep;13(9):1560-6 Authors: Francis DO, Vaezi MF Abstract Although laryngopharyngeal reflux, also known as extraesophageal reflux (EER), was codified more than 25 years ago, it has not been characterized fully. There is no sensitive and specific diagnostic test, and its symptoms often are nonspecific and overlap with those of other conditions commonly seen in primary care and specialist practices. Otolaryngolo... περισσότερα »

Clinical Case of the Month: A 48-Year-Old Man With Fever and Abdominal Pain of One Day Duration.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
*Clinical Case of the Month: A 48-Year-Old Man With Fever and Abdominal Pain of One Day Duration.* J La State Med Soc. 2015 Sep-Oct;167(5):237-240 Authors: Yu M, Tadin D, Conrad EJ, Lopez FA Abstract A 48-year-old man residing in a mental health department inpatient program with a history of schizoaffective disorder presented to the emergency department with a chief complaint of fever and intense abdominal pain for one day. The patient stated he initially fell in the shower and afterwards experienced back pain. He was transferred to an acute care unit within the facility for furt...περισσότερα »

A service evaluation of cough reflex testing to guide dysphagia management in the postsurgical adult head and neck patient population.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
*A service evaluation of cough reflex testing to guide dysphagia management in the postsurgical adult head and neck patient population.* Curr Opin Otolaryngol Head Neck Surg. 2016 Jun;24(3):191-196 Authors: Holmes S Abstract PURPOSE OF REVIEW: The article reviews recent literature supporting the use of cough reflex testing (CRT), and outlines a service evaluation of CRT conducted with postsurgical head and neck cancer patients. There is a growing evidence base to support the use of CRT in dysphagia management to establish laryngeal sensation and screen for silent aspiration; howev...περισσότερα »

THE ACHES THAT TAKE YOUR BREATH (AND TEARS) AWAY.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
*THE ACHES THAT TAKE YOUR BREATH (AND TEARS) AWAY.* J La State Med Soc. 2015 May-Jun;167(3):154-155 Authors: Becerril J, Gonzales H, Saketkoo LA Abstract An 80-year-old man presented with a complaint of three months of fatigue and aching of his shoulders and hips, as well as pain, swelling, and stiffness in bilateral fingers that was worse in the morning but improved with movement. Associated symptoms included worsening dry mouth and eyes, dysphagia, exertional dyspnea, and right foot drop. Physical exam was significant for edematous and tender bilateral proximal interphalangeal ...περισσότερα »

Refractory Orthostatic Hypotension Caused by a Recurrent Hemangioblastoma: Case Report and Review of the Literature.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
*Refractory Orthostatic Hypotension Caused by a Recurrent Hemangioblastoma: Case Report and Review of the Literature.* Cureus. 2016;8(3):e540 Authors: Nangunoori R, Koduri S, Singh A, Aziz K Abstract Refractory orthostatic hypotension (OH) has been described following surgery for posterior fossa tumors. We present the case of a patient with refractory OH following attempted surgical resection. We also reviewed the available literature to describe pathophysiologic mechanisms for this rare entity. A 58-year-old female was found to have a hemangioblastoma at the cervicomedullary jun... περισσότερα »

Eosinophilic esophagitis in adults: An update.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
*Eosinophilic esophagitis in adults: An update.* World J Gastrointest Pharmacol Ther. 2016 May 6;7(2):207-13 Authors: Ahmed M Abstract Eosinophilic esophagitis is a worldwide chronic allergic disease of the esophagus. In the last decade, there is an epidemic of this entity in the western world. Mostly seen in children and young adults, patients present with dysphagia or food impaction in the emergency room. Characteristic endoscopic findings, esophageal eosinophilia and non-responsiveness to proton pump inhibitors help make the diagnosis. Avoidance of food allergens, administrati... περισσότερα »

Transoral incisionless fundoplication for gastro-esophageal reflux disease: Techniques and outcomes.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
*Transoral incisionless fundoplication for gastro-esophageal reflux disease: Techniques and outcomes.* World J Gastrointest Pharmacol Ther. 2016 May 6;7(2):179-89 Authors: Testoni PA, Mazzoleni G, Testoni SG Abstract Gastro-esophageal reflux disease (GERD) is a very common disorder that results primarily from the loss of an effective antireflux barrier, which forms a mechanical obstacle to the retrograde movement of gastric content. GERD can be currently treated by medical therapy, surgical or endoscopic transoral intervention. Medical therapy is the most common approach, though ...περισσότερα »

Levodopa responsiveness of dysphagia in advanced Parkinson's disease and reliability testing of the FEES-Levodopa-test.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
*Levodopa responsiveness of dysphagia in advanced Parkinson's disease and reliability testing of the FEES-Levodopa-test.* Parkinsonism Relat Disord. 2016 Apr 28; Authors: Warnecke T, Suttrup I, Schröder JB, Osada N, Oelenberg S, Hamacher C, Suntrup S, Dziewas R Abstract BACKGROUND: It is still controversially discussed whether central dopaminergic stimulation improves swallowing ability in Parkinson's disease (PD). We evaluated the effect of oral levodopa application on dysphagia in advanced PD patients with motor fluctuations. METHODS: In 15 PD patients (mean age 71.93 ± 8.29 yea...περισσότερα »

Dosimetric advantages of intensity-modulated proton therapy for oropharyngeal cancer compared with intensity-modulated radiation: A case-matched control analysis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
*Dosimetric advantages of intensity-modulated proton therapy for oropharyngeal cancer compared with intensity-modulated radiation: A case-matched control analysis.* Med Dosim. 2016 May 3; Authors: Holliday EB, Kocak-Uzel E, Feng L, Thaker NG, Blanchard P, Rosenthal DI, Gunn GB, Garden AS, Frank SJ Abstract A potential advantage of intensity-modulated proton therapy (IMPT) over intensity-modulated (photon) radiation therapy (IMRT) in the treatment of oropharyngeal carcinoma (OPC) is lower radiation dose to several critical structures involved in the development of nausea and vomit...περισσότερα »

Developmental abnormalities of the craniocervical junction resulting in collet-sicard syndrome.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
*Developmental abnormalities of the craniocervical junction resulting in collet-sicard syndrome.* Spine J. 2016 May 5; Authors: Kang K, Moon BG Abstract BACKGROUND CONTEXT: Collet-Sicard Syndrome describes paralysis of cranial nerves IX-XII and is the most frequently reported neurological complication associated with Jefferson fractures. As the lateral mass of the atlas is displaced laterally toward the styloid process and the stylohyoid ligament, it impinges on cranial nerves IX-XII. However, Collet-Sicard syndrome in association with other anomalies of the atlas has rarely been... περισσότερα »

[Use of gastrostomies in patients over 75 years old].

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
*[Use of gastrostomies in patients over 75 years old].* Rev Esp Geriatr Gerontol. 2016 May 5; Authors: Baeza-Monedero ME, Montero-Errasquín B, Sánchez-Corral J, Cruz-Jentoft AJ Abstract OBJECTIVE: To describe the indications of insertion of a percutaneous gastrostomy (PG) in older patients in a university hospital, as well as patient characteristics, short and long term complications, and mortality. METHODS: Retrospective descriptive study of all patients over 75 years who had a PG inserted during a three year period by the Interventional Radiology Department. The indication of th... περισσότερα »

Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.* Ann Surg. 2016 Feb;263(2):251-7 Authors: Maret-Ouda J, Konings P, Lagergren J, Brusselaers N Abstract OBJECTIVE: To investigate the preventive effect of antireflux surgery against esophageal adenocarcinoma (EAC) compared with medical treatment of gastroesophageal reflux disease (GERD) and to the background population. BACKGROUND: GERD is causally associated with EAC. Effective symptomatic treatment can be achieved with... περισσότερα »

Thoracic endovascular aortic repair for blunt thoracic aortic injuries in complex aortic arch vessels anatomies.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Thoracic endovascular aortic repair for blunt thoracic aortic injuries in complex aortic arch vessels anatomies.* Ann Vasc Surg. 2015 Aug;29(6):1320.e11-5 Authors: Piffaretti G, Carrafiello G, Ierardi AM, Mariscalco G, Macchi E, Castelli P, Tozzi M, Franchin M Abstract The aim of this study is to report the use of thoracic endovascular aortic repair (TEVAR) in blunt thoracic aortic injuries (BTAIs) presenting with complex anatomies of the aortic arch vessels. Two patients were admitted to our hospital for the mana... περισσότερα »

Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis.* Respir Care. 2015 Feb;60(2):244-50 Authors: Lee AL, Button BM, Denehy L, Roberts S, Bamford T, Mu FT, Mifsud N, Stirling R, Wilson JW Abstract BACKGROUND: Acid gastroesophageal reflux is a common problem in non-cystic fibrosis bronchiectasis and COPD. Invasive methods are used to diagnose gastroesophageal reflux, but the ability to detect pulmonary microaspiration of gastric contents using this met... περισσότερα »

Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.* Clin Gastroenterol Hepatol. 2015 Sep;13(9):1560-6 Authors: Francis DO, Vaezi MF Abstract Although laryngopharyngeal reflux, also known as extraesophageal reflux (EER), was codified more than 25 years ago, it has not been characterized fully. There is no sensitive and specific diagnostic test, and its symptoms often are nonspecific and overlap with those of other conditions commonly seen in primary care and specialist practices. Otolaryngolo... περισσότερα »

Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 10 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.* Ann Surg. 2016 Feb;263(2):251-7 Authors: Maret-Ouda J, Konings P, Lagergren J, Brusselaers N Abstract OBJECTIVE: To investigate the preventive effect of antireflux surgery against esophageal adenocarcinoma (EAC) compared with medical treatment of gastroesophageal reflux disease (GERD) and to the background population. BACKGROUND: GERD is causally associated with EAC. Effective symptomatic treatment can be achieved wit... περισσότερα »

Temporomandibular Myofacial Pain Treated with Botulinum Toxin Injection.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 11 δευτερόλεπτα
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Temporomandibular Myofacial Pain Treated with Botulinum Toxin Injection.* Toxins (Basel). 2015 Aug;7(8):2791-800 Authors: Mor N, Tang C, Blitzer A Abstract This article reviews the diagnoses and treatment of temporomandibular disorders (TMD) and outlines of the role of botulinum toxin (BoNT) in the treatment of myofacial TMD. This manuscript includes a brief history of the use of BoNT in the treatment of pain, the mechanism of action of BoNT, and the techniques for injections, adverse effects and contraindications when using... περισσότερα »

Eloquent silences: A musical and lexical analysis of conversation between oncologists and their patients.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 11 δευτερόλεπτα
*Eloquent silences: A musical and lexical analysis of conversation between oncologists and their patients.* Patient Educ Couns. 2016 Apr 20; Authors: Bartels J, Rodenbach R, Ciesinski K, Gramling R, Fiscella K, Epstein R Abstract OBJECTIVE: Silences in doctor-patient communication can be "connectional" and communicative, in contrast to silences that indicate awkwardness or distraction. Musical and lexical analyses can identify and characterize connectional silences in consultations between oncologists and patients. METHODS: Two medical students and a professor of voice screened al... περισσότερα »

Student voice - Getting motivated.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 11 δευτερόλεπτα
*Student voice - Getting motivated.* Nurs Child Young People. 2016 May 9;28(4):14 Authors: Cowen E Abstract ON THE whole, I consider myself a calm, logical person who rarely gets stressed. This stands me in good stead on placement, but it causes problems when it comes to the academic side of being a student. I rarely start work when I should. I have not yet started an essay the night before it is due, but it is unheard of for me to start an essay sooner than two weeks before it is due. PMID: 27156417 [PubMed - in process] from Speech via xlomafota13 on Inoreader http://ift.tt/2... περισσότερα »

Temporomandibular Myofacial Pain Treated with Botulinum Toxin Injection.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 11 δευτερόλεπτα
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Temporomandibular Myofacial Pain Treated with Botulinum Toxin Injection.* Toxins (Basel). 2015 Aug;7(8):2791-800 Authors: Mor N, Tang C, Blitzer A Abstract This article reviews the diagnoses and treatment of temporomandibular disorders (TMD) and outlines of the role of botulinum toxin (BoNT) in the treatment of myofacial TMD. This manuscript includes a brief history of the use of BoNT in the treatment of pain, the mechanism of action of BoNT, and the techniques for injections, adverse effects and contraindications when using... περισσότερα »

Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 11 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.* Clin Gastroenterol Hepatol. 2015 Sep;13(9):1560-6 Authors: Francis DO, Vaezi MF Abstract Although laryngopharyngeal reflux, also known as extraesophageal reflux (EER), was codified more than 25 years ago, it has not been characterized fully. There is no sensitive and specific diagnostic test, and its symptoms often are nonspecific and overlap with those of other conditions commonly seen in primary care and specialist practices. Otolaryngol... περισσότερα »

Intrahepatic IP-10 mRNA and plasma IP-10 levels as response marker for HBeAg-positive chronic hepatitis B patients treated with peginterferon and adefovir

AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 13 δευτερόλεπτα
Antiviral Research from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1OdOL3f via IFTTT

Breathing and Singing: Objective Characterization of Breathing Patterns in Classical Singers.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 47 δευτερόλεπτα
*Breathing and Singing: Objective Characterization of Breathing Patterns in Classical Singers.* PLoS One. 2016;11(5):e0155084 Authors: Salomoni S, van den Hoorn W, Hodges P Abstract Singing involves distinct respiratory kinematics (i.e. movements of rib cage and abdomen) to quiet breathing because of different demands on the respiratory system. Professional classical singers often advocate for the advantages of an active control of the abdomen on singing performance. This is presumed to prevent shortening of the diaphragm, elevate the rib cage, and thus promote efficient generati... περισσότερα »

Implementing Community Engagement as a Mission at the David Geffen School of Medicine at the University of California, Los Angeles.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 47 δευτερόλεπτα
*Implementing Community Engagement as a Mission at the David Geffen School of Medicine at the University of California, Los Angeles.* J Health Care Poor Underserved. 2016 Feb;27(1):8-21 Authors: Chung B, Brown A, Moreno G, Cuen P, Uy V, Vangala S, Bell D, Washington AE, Norris KC, Mangione C Abstract This manuscript describes the development and implementation of community engagement as a mission at UCLA's David Geffen School of Medicine (DGSOM) and UCLA Health System, and summarizes survey results documenting existing community-engaged projects and interest between 2010 to 2013. ... περισσότερα »

Efficacy of three-dimensional visualization in mobile apps for patient education regarding orthognathic surgery.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 47 δευτερόλεπτα
*Efficacy of three-dimensional visualization in mobile apps for patient education regarding orthognathic surgery.* Int J Oral Maxillofac Surg. 2016 May 3; Authors: Pulijala Y, Ma M, Ju X, Benington P, Ayoub A Abstract 'Sur-face' is an interactive mobile app illustrating different orthognathic surgeries and their potential complications. This study aimed to evaluate the efficacy of Sur-face by comparing two methods of delivering patient information on orthognathic surgeries and their related potential complications: a mobile app with interactive three-dimensional (3D) animations a... περισσότερα »

Transcranial Alternating Current Stimulation (tACS) differentially modulates speech perception in young and older adults.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 47 δευτερόλεπτα
*Transcranial Alternating Current Stimulation (tACS) differentially modulates speech perception in young and older adults.* Brain Stimul. 2016 Apr 6; Authors: Rufener KS, Oechslin MS, Zaehle T, Meyer M Abstract BACKGROUND: Normal aging is accompanied by a functional decline in processing temporal features of spoken language, such as voice onset time (VOT). On an electrophysiological level, this finding is paralleled by altered patterns of gamma oscillations. OBJECTIVE: Using 40 Hz transcranial alternating current stimulation (tACS) over the bilateral auditory cortex, this study ai... περισσότερα »

Eloquent silences: A musical and lexical analysis of conversation between oncologists and their patients.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 47 δευτερόλεπτα
*Eloquent silences: A musical and lexical analysis of conversation between oncologists and their patients.* Patient Educ Couns. 2016 Apr 20; Authors: Bartels J, Rodenbach R, Ciesinski K, Gramling R, Fiscella K, Epstein R Abstract OBJECTIVE: Silences in doctor-patient communication can be "connectional" and communicative, in contrast to silences that indicate awkwardness or distraction. Musical and lexical analyses can identify and characterize connectional silences in consultations between oncologists and patients. METHODS: Two medical students and a professor of voice screened al... περισσότερα »

Student voice - Getting motivated.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 47 δευτερόλεπτα
*Student voice - Getting motivated.* Nurs Child Young People. 2016 May 9;28(4):14 Authors: Cowen E Abstract ON THE whole, I consider myself a calm, logical person who rarely gets stressed. This stands me in good stead on placement, but it causes problems when it comes to the academic side of being a student. I rarely start work when I should. I have not yet started an essay the night before it is due, but it is unheard of for me to start an essay sooner than two weeks before it is due. PMID: 27156417 [PubMed - in process] from Speech via xlomafota13 on Inoreader http://ift.tt/2... περισσότερα »

Temporomandibular Myofacial Pain Treated with Botulinum Toxin Injection.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 47 δευτερόλεπτα
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Temporomandibular Myofacial Pain Treated with Botulinum Toxin Injection.* Toxins (Basel). 2015 Aug;7(8):2791-800 Authors: Mor N, Tang C, Blitzer A Abstract This article reviews the diagnoses and treatment of temporomandibular disorders (TMD) and outlines of the role of botulinum toxin (BoNT) in the treatment of myofacial TMD. This manuscript includes a brief history of the use of BoNT in the treatment of pain, the mechanism of action of BoNT, and the techniques for injections, adverse effects and contraindications when using ... περισσότερα »

Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 47 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.* Clin Gastroenterol Hepatol. 2015 Sep;13(9):1560-6 Authors: Francis DO, Vaezi MF Abstract Although laryngopharyngeal reflux, also known as extraesophageal reflux (EER), was codified more than 25 years ago, it has not been characterized fully. There is no sensitive and specific diagnostic test, and its symptoms often are nonspecific and overlap with those of other conditions commonly seen in primary care and specialist practices. Otolaryngolo... περισσότερα »

The redox protein p66(shc) mediates cochlear vascular dysfunction and transient noise-induced hearing loss.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
*The redox protein p66(shc) mediates cochlear vascular dysfunction and transient noise-induced hearing loss.* Sci Rep. 2016;6:25450 Authors: Fetoni AR, Eramo SL, Paciello F, Rolesi R, Samengo D, Paludetti G, Troiani D, Pani G Abstract p66(shc), a member of the ShcA protein family, is essential for cellular response to oxidative stress, and elicits the formation of mitochondrial Reactive Oxygen Species (ROS), thus promoting vasomotor dysfunction and inflammation. Accordingly, mice lacking the p66 isoform display increased resistance to oxidative tissue damage and to cardiovascular...περισσότερα »

Components of Metabolic Syndrome as Risk Factors for Hearing Threshold Shifts.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Components of Metabolic Syndrome as Risk Factors for Hearing Threshold Shifts.* PLoS One. 2015;10(8):e0134388 Authors: Sun YS, Fang WH, Kao TW, Yang HF, Peng TC, Wu LW, Chang YW, Chou CY, Chen WL Abstract BACKGROUND: Hearing loss was a common, chronically disabling condition in the general population and had been associated with several inflammatory diseases. Metabolic syndrome, which was associated with insulin resistance and visceral obesity, was considered a chronic inflammatory disea... περισσότερα »

Ischemic fasciitis: enhanced diagnostic resolution through clinical, histopathologic, and radiologic correlation in 17 cases

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Abstract Ischemic fasciitis is a pseudosarcomatous nodule or mass resulting from sustained or repeated pressure and consequent ischemia of soft tissue. Fibrin and hemorrhage expand its hypocellular epicenter bordered by enlarged (atypical, ischemic) fibroblasts and reactive vascular prominence resulting in diagnostically important histologic zonation. Although classically in bedridden patients, ischemic fasciitis due to posture-related intermittent pressure in ambulatory adults is not well characterized; there has not been a thorough review of its presentation in ambulatory patien... περισσότερα »

Cutaneous autoimmune effects in the setting of therapeutic immune checkpoint inhibition for metastatic melanoma

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Abstract Therapeutic immune checkpoint blockade for metastatic melanoma has been associated with vitiligo, pruritus, and morbilliform eruptions. Reports of other autoimmune skin disease in this setting are rare. We sought to expand the spectrum of cutaneous immune-mediated effects related to immune checkpoint inhibitor therapy. In this report, we describe two unusual cutaneous reactions related to checkpoint inhibitor therapy, namely bullous pemphigoid and dermatitis herpetiformis. The development of bullous pemphigoid and dermatitis herpetiformis in the context of checkpoint inhi...περισσότερα »

Papular acantholytic dyskeratosis of the anogenital and genitocrural area: case series and review of the literature

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
ABSTRACT Background Papular acantholytic dyskeratosis of the anogenital/genitocrural area is described as a rare distinct clinicopathological entity known to dermatopathologists although its characteristic histopathologic pattern resembles both Hailey-Hailey disease and Darier disease. Objective To describe the clinical characteristics, histopathologic features and response to treatment of papular acantholytic dyskeratosis. Methods We report in details 6 cases of papular acantholytic dyskeratosis. A literature search of the keyword "papular acantholytic dyskeratosis" was perfor... περισσότερα »

Patient perception of wound photography

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Patient perception of wound photography: Abstract The objectives of this study were to provide an assessment of photographic documentation of the wound from the patients' perspective and to evaluate whether this could improve patients' understanding of and involvement in their wound care. Our results revealed that most patients visiting the wound care clinic have difficult-to-see wounds (86%). Only 20% of patients monitor their wounds and instead rely on clinic or nurse visits to track the healing progress. There was a significant association between patients' ability to see their ... περισσότερα »

Fluoroscopically guided large balloon dilatation for treating congenital esophageal stenosis in children.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *Fluoroscopically guided large balloon dilatation for treating congenital esophageal stenosis in children.* Jpn J Radiol. 2015 Jul;33(7):418-23 Authors: Hu HT, Shin JH, Kim JH, Jang JK, Park JH, Kim TH, Nam DH, Song HY Abstract PURPOSE: We aimed to evaluate the safety and clinical effectiveness of fluoroscopically guided large balloon dilatation for treating congenital esophageal stenosis in children. METHODS: Our study included seven children (mean age 4.0 years) who underwent a total of ten balloon dilatation ses... περισσότερα »

Carcinoma of the superior mediastinal segment of the esophagus; a technique for resection with restoration of continuity of the alimentary canal.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα
Related Articles *Carcinoma of the superior mediastinal segment of the esophagus; a technique for resection with restoration of continuity of the alimentary canal.* Surgery. 1948 Dec;24(6):929-38 Authors: SWEET RH PMID: 18099796 [PubMed - indexed for MEDLINE] from #Esophageal Cancer via xlomafota13 on Inoreader http://ift.tt/1T34WNH via IFTTT

Resection of thoracic esophagus for carcinoma located above arch of aorta; cervical esophagogastrostomy.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα
Related Articles *Resection of thoracic esophagus for carcinoma located above arch of aorta; cervical esophagogastrostomy.* Surgery. 1948 Jul;24(1):1-8 Authors: GARLOCK JH PMID: 18872828 [PubMed - indexed for MEDLINE] from #Esophageal Cancer via xlomafota13 on Inoreader http://ift.tt/1TBSNOV via IFTTT

Coexistence of resistance to thyroid hormone and papillary thyroid carcinoma

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 1 ώρα
Summary Resistance to thyroid hormone (RTH) is a syndrome of reduced tissue responsiveness to thyroid hormones. RTH is majorly caused by mutations in the thyroid hormone receptor beta (*THRB*) gene. Recent studies indicated a close association of *THRB* mutations with human cancers, but the role of *THRB* mutation in carcinogenesis is still unclear. Here, we report a rare case of RTH with a papillary thyroid carcinoma (PTC). A 26-year-old woman was referred to our hospital due to a thyroid tumor and hormonal abnormality. She had elevated serum thyroid hormones and non-suppressed ... περισσότερα »

[The Significance of Resection of the Cricoid Cartilage as a Surgical Procedure in Laryngotracheal Surgery].

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 1 ώρα
Related Articles *[The Significance of Resection of the Cricoid Cartilage as a Surgical Procedure in Laryngotracheal Surgery].* Nihon Jibiinkoka Gakkai Kaiho. 2015 Oct;118(10):1233-40 Authors: Hirai T, Fukushima N, Kano M, Miyahara N, Miyoshi A, Ariki M, Masuda S, Nagamine H Abstract The cricoid cartilage has been regarded as an extremely important organ because it plays important role in both of phonation and breathing. We herein report on two different types of surgical procedure for laryngotracheal diseases with aggressive resection of the cricoid cartilage. The first procedu... περισσότερα »

Methylation Markers for Early Detection and Differentiation of Follicular Thyroid Cancer Subtypes.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 1 ώρα
*Methylation Markers for Early Detection and Differentiation of Follicular Thyroid Cancer Subtypes.* Cancer Clin Oncol. 2015 Nov;4(2):1-12 Authors: Stephen JK, Chen KM, Merritt J, Chitale D, Divine G, Worsham MJ Abstract Thyroid cancer has the fastest rising incidence rates and is the fifth most common cancer in women. There are four main types of which the papillary and follicular types together account for >90%, followed by medullary cancers (3%-5%) and anaplastic carcinomas (<3%). For individuals who present with early stage disease of papillary and follicular cancers, there a...περισσότερα »

Ratiometric detection and imaging of endogenous hypochlorite in live cells and in vivo achieved by using an aggregation induced emission (AIE)-based nanoprobe

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC03415B, Communication yong huang, Peisheng Zhang, Meng Gao, Fang Zeng, Anjun Qin, Shuizhu Wu, Ben Zhong Tang This is an Accepted Manuscript, which has been through the RSC Publishing peer review process and has been accepted for publication. Accepted manuscripts are published online shortly after acceptance. This version of the article will be replaced by the fully edited, formatted and proof read Advance Article as soon as this is available. The content of this RSS Feed (c) The Royal Society of Chem... περισσότερα »

Postsynthetic Modification of Cadmium-Based Links and Knots

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC02423H, Communication Ali Trabolsi, Thirumugan Prakasam, Rana A. Bilbeisi, matteo lusi, John-Carl Olsen, Carlos Platas-Iglesias Three topologically non-trivial cadmium(II)-based complexes-Cd-[2]C, Cd-TK and Cd-SL-were simultaneously self-assembled in a dynamic library, individually isolated and fully characterized by solid-state, gas-phase and solution-phase techniques. Post-synthetic modifications, including reduction and... The content of this RSS Feed (c) The Royal Society of Chemistry from BioC...περισσότερα »

Gold Coated Magnetic Nanoparticles: Preparation, Surface Modification for Analytical and Biomedical Applications

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC03225G, Feature Article Saimon Moraes Silva, Roya Tavallaie, Lydia Sandiford, Richard Tilley, John Justin Gooding Gold coated magnetic nanoparticles (Au@MNPs) have become increasingly interesting to nanomaterial scientists due to their multifunctional properties and their potential in both analytical chemistry and nanomedicine. The past decade has... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/24Joqlh via IFTTT

Double-Diffusion-Based Synthesis of BiVO4 Mesoporous Single Crystals with Enhanced Photocatalytic Activity for Oxygen Evolution

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC02737G, Communication Qiangfang Wu, Shenyuan Bao, Baozhu Tian, Yifei Xiao, Jinlong Zhang BiVO4 mesoporous single crystals (MSCs) were successfully prepared, for the first time, by a one-step hydrothermal method using the acidified BiVO4 precursor solution pre-impregnated silica as the template. It was... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/24JonG1 via IFTTT

Thoracic endovascular aortic repair for blunt thoracic aortic injuries in complex aortic arch vessels anatomies.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Thoracic endovascular aortic repair for blunt thoracic aortic injuries in complex aortic arch vessels anatomies.* Ann Vasc Surg. 2015 Aug;29(6):1320.e11-5 Authors: Piffaretti G, Carrafiello G, Ierardi AM, Mariscalco G, Macchi E, Castelli P, Tozzi M, Franchin M Abstract The aim of this study is to report the use of thoracic endovascular aortic repair (TEVAR) in blunt thoracic aortic injuries (BTAIs) presenting with complex anatomies of the aortic arch vessels. Two patients were admitted to our hospital for the man... περισσότερα »

Investigation of Dysphagia After Antireflux Surgery by High-resolution Manometry: Impact of Multiple Water Swallows and a Solid Test Meal on Diagnosis, Management, and Clinical Outcome.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Investigation of Dysphagia After Antireflux Surgery by High-resolution Manometry: Impact of Multiple Water Swallows and a Solid Test Meal on Diagnosis, Management, and Clinical Outcome.* Clin Gastroenterol Hepatol. 2015 Sep;13(9):1575-83 Authors: Wang YT, Tai LF, Yazaki E, Jafari J, Sweis R, Tucker E, Knowles K, Wright J, Ahmad S, Kasi M, Hamlett K, Fox MR, Sifrim D Abstract BACKGROUND & AIMS: Management of patients with dysphagia, regurgitation, and related symptoms after antireflux surgery is challenging. This ... περισσότερα »

Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis.* Respir Care. 2015 Feb;60(2):244-50 Authors: Lee AL, Button BM, Denehy L, Roberts S, Bamford T, Mu FT, Mifsud N, Stirling R, Wilson JW Abstract BACKGROUND: Acid gastroesophageal reflux is a common problem in non-cystic fibrosis bronchiectasis and COPD. Invasive methods are used to diagnose gastroesophageal reflux, but the ability to detect pulmonary microaspiration of gastric contents using this me... περισσότερα »

Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.* Clin Gastroenterol Hepatol. 2015 Sep;13(9):1560-6 Authors: Francis DO, Vaezi MF Abstract Although laryngopharyngeal reflux, also known as extraesophageal reflux (EER), was codified more than 25 years ago, it has not been characterized fully. There is no sensitive and specific diagnostic test, and its symptoms often are nonspecific and overlap with those of other conditions commonly seen in primary care and specialist practices. Otolaryngol... περισσότερα »

Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.* Ann Surg. 2016 Feb;263(2):251-7 Authors: Maret-Ouda J, Konings P, Lagergren J, Brusselaers N Abstract OBJECTIVE: To investigate the preventive effect of antireflux surgery against esophageal adenocarcinoma (EAC) compared with medical treatment of gastroesophageal reflux disease (GERD) and to the background population. BACKGROUND: GERD is causally associated with EAC. Effective symptomatic treatment can be achieved with... περισσότερα »

Temporomandibular Myofacial Pain Treated with Botulinum Toxin Injection.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Temporomandibular Myofacial Pain Treated with Botulinum Toxin Injection.* Toxins (Basel). 2015 Aug;7(8):2791-800 Authors: Mor N, Tang C, Blitzer A Abstract This article reviews the diagnoses and treatment of temporomandibular disorders (TMD) and outlines of the role of botulinum toxin (BoNT) in the treatment of myofacial TMD. This manuscript includes a brief history of the use of BoNT in the treatment of pain, the mechanism of action of BoNT, and the techniques for injections, adverse effects and contraindications when using ... περισσότερα »

Thoracic endovascular aortic repair for blunt thoracic aortic injuries in complex aortic arch vessels anatomies.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Thoracic endovascular aortic repair for blunt thoracic aortic injuries in complex aortic arch vessels anatomies.* Ann Vasc Surg. 2015 Aug;29(6):1320.e11-5 Authors: Piffaretti G, Carrafiello G, Ierardi AM, Mariscalco G, Macchi E, Castelli P, Tozzi M, Franchin M Abstract The aim of this study is to report the use of thoracic endovascular aortic repair (TEVAR) in blunt thoracic aortic injuries (BTAIs) presenting with complex anatomies of the aortic arch vessels. Two patients were admitted to our hospital for the mana... περισσότερα »

Investigation of Dysphagia After Antireflux Surgery by High-resolution Manometry: Impact of Multiple Water Swallows and a Solid Test Meal on Diagnosis, Management, and Clinical Outcome.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Investigation of Dysphagia After Antireflux Surgery by High-resolution Manometry: Impact of Multiple Water Swallows and a Solid Test Meal on Diagnosis, Management, and Clinical Outcome.* Clin Gastroenterol Hepatol. 2015 Sep;13(9):1575-83 Authors: Wang YT, Tai LF, Yazaki E, Jafari J, Sweis R, Tucker E, Knowles K, Wright J, Ahmad S, Kasi M, Hamlett K, Fox MR, Sifrim D Abstract BACKGROUND & AIMS: Management of patients with dysphagia, regurgitation, and related symptoms after antireflux surgery is challenging. This p... περισσότερα »

Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis.* Respir Care. 2015 Feb;60(2):244-50 Authors: Lee AL, Button BM, Denehy L, Roberts S, Bamford T, Mu FT, Mifsud N, Stirling R, Wilson JW Abstract BACKGROUND: Acid gastroesophageal reflux is a common problem in non-cystic fibrosis bronchiectasis and COPD. Invasive methods are used to diagnose gastroesophageal reflux, but the ability to detect pulmonary microaspiration of gastric contents using this met... περισσότερα »

Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Should the Reflex Be Reflux? Throat Symptoms and Alternative Explanations.* Clin Gastroenterol Hepatol. 2015 Sep;13(9):1560-6 Authors: Francis DO, Vaezi MF Abstract Although laryngopharyngeal reflux, also known as extraesophageal reflux (EER), was codified more than 25 years ago, it has not been characterized fully. There is no sensitive and specific diagnostic test, and its symptoms often are nonspecific and overlap with those of other conditions commonly seen in primary care and specialist practices. Otolaryngolo... περισσότερα »

A prospective study of oral contraceptive use and colorectal adenomas

Cancer Causes and Control from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1OdOKMM via IFTTT

Chinese Herbal Medicine and Fluorouracil-Based Chemotherapy for Colorectal Cancer: A Quality-Adjusted Meta-Analysis of Randomized Controlled Trials

Integrative Cancer Therapies from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TBJoHl via IFTTT

Association of Selective Serotonin Reuptake Inhibitors with Transfusion in Surgical Patients.

BACKGROUND: The clinical relevance of chronic exposure to selective serotonin reuptake inhibitors (SSRIs) to transfusion in surgical patients is unclear. METHODS: We conducted a prospective cohort study involving patients undergoing cardiac, vascular, spinal, and intracranial surgery at 2 academic medical centers. Medication use, demographics, comorbidities, and laboratory values were determined at baseline by patient interview and review of medical records. The primary outcome was transfusion of any hemostatic allogeneic blood product (i.e., fresh frozen plasma, platelets, and/or c... περισσότερα »

Coverage for hepatitis C drugs in medicare part D

The American Journal of Managed Care from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1OdOHR9 via IFTTT

The predictive value of noninvasive serum markers of liver fibrosis in patients with chronic hepatitis C

The Turkish Journal of Gastroenterology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TBJm2b via IFTTT

Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study

International Journal of Cancer from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1OdOHQR via IFTTT

Ethnic variations in duodenal villous atrophy consistent with celiac disease in the United States

Clinical Gastroenterology and Hepatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TBJm1T via IFTTT

An update of the WCRF/AICR systematic literature review on esophageal and gastric cancers and citrus fruits intake

Cancer Causes and Control from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1OdOFbT via IFTTT

A study on morbidity and mortality pattern of poisoning in tertiary care hospital

2016-05-10T03-58-17Z *Source:* International Journal of Research in Medical Sciences C. Paranthakan, P.K.Govindarajan. Background: The poisoning due to various reasons commonly occurs among population. Normally tertiary care hospitals receive large numbers of referral. During treatment many die due to poisoning. Objectives of the study were to find out the magnitude of admissions due to poisoning and to find out various type of poisoning and related mortality. Methods: The secondary data was collected from records available in Intensive care unit of toxicology department of tertiary...περισσότερα »

Assessment of fetal malnutrition by body mass index and intra uterine growth curves: a comparative study

2016-05-10T03-45-13Z *Source:* International Journal of Contemporary Pediatrics Madhava Kamath K., Swathi S. Rao, Rathika D. Shenoy. Background: Assessment of fetal malnutrition (FM) is incomplete by intra uterine growth (IUG) charts where only single anthropometric measure like weight is used. Body mass index (BMI) is a weight to length ratio which is a sensitive indicator of malnutrition. This study was aimed at comparing the accuracy of various birth weight based IUG charts with Body mass index of the new-born babies in detection of FM and correlating the neonatal complications w...περισσότερα »

A prospective study of autoantibodies to Ezrin and pancreatic cancer risk

Cancer Causes and Control from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1OdOH3r via IFTTT

Exercise-based interventions for non-alcoholic fatty liver disease: a meta-analysis and meta-regression

Clinical Gastroenterology and Hepatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TBJlv3 via IFTTT

The Feasibility and Utility of Continuous Sleep Monitoring in Critically Ill Patients Using a Portable Electroencephalography Monitor.

BACKGROUND: Sleep disruption in critically ill adults can result in acute decrements in cognitive function, including delirium, but it is underdiagnosed in the setting of the intensive care unit (ICU). Although sleep stages can be assessed by polysomnography (PSG), acquisition and interpretation of PSG is costly, is labor intensive, is difficult to do over an extended period of time with critically ill patients (multiple days of continuous recording), and may interfere with patient care. In this pilot study, we investigated the feasibility and utility of monitoring sleep in the ICU ... περισσότερα »

Association between breast cancer recurrence with immunosuppression in rheumatoid arthritis and inflammatory bowel disease: A cohort study

Arthritis & Rheumatism from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1OdOEEX via IFTTT

Neuraxial Anesthesia in Parturients with Low Platelet Counts.

The obstetric anesthesiologist must consider the risk of spinal-epidural hematoma in patients with thrombocytopenia when choosing to provide neuraxial anesthesia. There are little data exploring this complication in the parturient. In this single-center retrospective study of 20,244 obstetric patients, the incidence of peripartum thrombocytopenia (platelet count from Anaesthesiology via xlomafota13 on Inoreader http://ift.tt/1T0JtZ1 via IFTTT

The CNAP(TM) Finger Cuff for Noninvasive Beat-To-Beat Monitoring of Arterial Blood Pressure: An Evaluation in Intensive Care Unit Patients and a Comparison with 2 Intermittent Devices.

BACKGROUND: Continuous and intermittent noninvasive measurements of arterial blood pressure (BP) have not been compared in the same population. In a large panel of intensive care unit patients, we assessed the agreement between CNAP(TM) (Continuous Noninvasive Arterial Pressure) finger cuff beat-to-beat monitoring of BP and reference intraarterial measurements. Two automated oscillometric brachial cuff devices were also tested: CNAP brachial cuff (used for CNAP finger cuff calibration) and an alternative device. The performance for detecting hypotension (intraarterial mean BP 10%), ...περισσότερα »

The Effect of Local Anesthetic Volume Within the Adductor Canal on Quadriceps Femoris Function Evaluated by Electromyography: A Randomized, Observer- and Subject-Blinded, Placebo-Controlled Study in Volunteers.

BACKGROUND: Single-injection adductor canal block (ACB) provides analgesia after knee surgery. Which nerves that are blocked by an ACB and what influence-if any-local anesthetic volume has on the effects remain undetermined. We hypothesized that effects on the nerve to the vastus medialis muscle (which besides being a motor nerve innervates portions of the knee) are volume-dependent. METHODS: In this assessor- and subject-blinded randomized trial, 20 volunteers were included. On 3 separate days, subjects received an ACB with different volumes (10, 20, and 30 mL) of lidocaine 1%. In ...περισσότερα »

ARCII: A phase II trial of the HIV protease inhibitor Nelfinavir in combination with chemoradiation for locally advanced inoperable pancreatic cancer

Radiotherapy & Oncology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1rPqSEY via IFTTT

Preoperative Troponin in Patients Undergoing Noncardiac Surgery: Is Timing Everything?.

No abstract available from Anaesthesiology via xlomafota13 on Inoreader http://ift.tt/1Yjaze4 via IFTTT

Advanced Diagnostic Genetic Testing In Inherited Retinal Disease:Experience from a Single Tertiary Referral Centre in the UK National Health Service

ABSTRACT Background/Aims In 2013, as part of our genetic investigation of patients with Inherited Retinal Disease, we utilised multigene panel testing of 105 genes known to cause retinal disease in our patient cohorts. This test was performed in a UK National Health Service (NHS) accredited laboratory. Method The results of all multigene panel tests requested between 1.4.13 and 31.8.14 were retrospectively reviewed. All patients had been previously seen at Moorfields Eye Hospital, London, UK and diagnosed with an inherited retinal dystrophy after clinical examination and detailed... περισσότερα »

Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer

Clinical Cancer Research from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1WXATvw via IFTTT

In vivo physiological recording from the lateral line of juvenile zebrafish

Hair cells are sensory receptors responsible for transducing auditory and vestibular information into electrical signals, which are then transmitted with remarkable precision to afferent neurons. The zebrafish lateral line is emerging as an excellent *in vivo* model for genetic and physiological analysis of hair cells and neurons. However, research has been limited to larval stages because zebrafish become protected from the time of independent feeding under European law (from 5.2 days post-fertilization, dpf, at 28.5°C). In larval zebrafish, the functional properties of hair cel... περισσότερα »

The Significance of Resection of the Cricoid Cartilage as a Surgical Procedure in Laryngotracheal Surgery.

Related Articles [The Significance of Resection of the Cricoid Cartilage as a Surgical Procedure in Laryngotracheal Surgery]. Nihon Jibiinkoka Gakkai Kaiho. 2015 Oct;118(10):1233-40 Authors: Hirai T, Fukushima N, Kano M, Miyahara N, Miyoshi A, Ariki M, Masuda S, Nagamine H Abstract The cricoid cartilage has been regarded as an extremely important organ because it plays […]

Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells.

Related Articles Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells. Cell Death Differ. 2015 Nov;22(11):1865-76 Authors: Stedman A, Beck-Cormier S, Le Bouteiller M, Raveux A, Vandormael-Pournin S, Coqueran S, Lejour V, Jarzebowski L, Toledo F, Robine S, Cohen-Tannoudji M Abstract Ribosome biogenesis is an essential cellular process. […]

Effect of three levels of dietary protein on metabolic phenotype of healthy individuals with 8 weeks of overfeeding.

Effect of three levels of dietary protein on metabolic phenotype of healthy individuals with 8 weeks of overfeeding. J Clin Endocrinol Metab. 2016 May 9;:jc20161313 Authors: Bray GA, Redman LM, de Jonge L, Rood J, Smith SR Abstract CONTEXT: Obesity is associated with insulin resistance and other metabolic changes which might be modified by overfeeding […]

IMBALANCE OF AMNIOTIC FLUID ACTIVIN-A AND FOLLISTATIN IN INTRA-AMNIOTIC INFECTION, INFLAMMATION AND PRETERM BIRTH.

IMBALANCE OF AMNIOTIC FLUID ACTIVIN-A AND FOLLISTATIN IN INTRA-AMNIOTIC INFECTION, INFLAMMATION AND PRETERM BIRTH. J Clin Endocrinol Metab. 2016 May 9;:jc20154147 Authors: Hardy JT, Buhimschi IA, McCarthy ME, Zhao G, Laky CA, Shook LL, Buhimschi CS Abstract CONTEXT: Microbial invasion of amniotic fluid (AF) cavity stimulates an inflammatory response that involves activin-A, a pleiotropic mediator […]

Pre-pregnancy factors as determinants of the development of diabetes mellitus after first pregnancy.

Pre-pregnancy factors as determinants of the development of diabetes mellitus after first pregnancy. J Clin Endocrinol Metab. 2016 May 9;:jc20153761 Authors: Joon Cho G, Heon Park J, Lee H, Yoo S, Shin SA, Oh MJ Abstract CONTEXT: The identification of modifiable factors at pre-pregnancy or early pregnancy as well as continued monitoring and management of […]

An audit of CT chest surveillance following oral cancer treatment.

An audit of CT chest surveillance following oral cancer treatment. Br J Oral Maxillofac Surg. 2016 May 3; Authors: Nugent G, Hughes T, Hanlon R, Jones HL, Rogers SN Abstract Computed tomography (CT) of the chest is an integral part of the staging of patients with oral cancer. It identifies metastases, synchronous pulmonary primaries, and […]

Measurements and source apportionment of particle-associated polycyclic aromatic hydrocarbons in ambient air in Riyadh, Saudi Arabia

Publication date: July 2016 Source:Atmospheric Environment, Volume 137 Author(s): Qijing Bian, Badr Alharbi, Jeffrey Collett, Sonia Kreidenweis, Mohammad J. Pasha Ambient air samples were obtained in Riyadh, the capital and largest city of Saudi Arabia, during two measurement campaigns spanning September 2011 to September 2012. Sixteen particle-phase polycyclic aromatic hydrocarbons (PAH) were quantified in 167 […]

Laryngeal Neuroendocrine Carcinomas: A Retrospective Study of 14 Cases.

Related Articles Laryngeal Neuroendocrine Carcinomas: A Retrospective Study of 14 Cases. Biomed Res Int. 2015;2015:832194 Authors: Zhu Y, Gao L, Meng Y, Diao W, Zhu X, Li G, Gao Z, Chen X Abstract Laryngeal neuroendocrine carcinomas (LNECs) are rare and highly heterogeneous which present a wide spectrum of pathological and clinical manifestations. Fourteen patients with […]

Modeling and simulation help optimize chemotherapy to combat brain tumor

St. Jude Children’s Research Hospital scientists have used sophisticated pharmacologic modeling and simulation to translate preclinical findings into a successful phase I clinical trial of a… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1rPejt8 via IFTTT

Journal of Behavioral Medicine, Vol. 39, Issue 3 – New Issue Alert

If this email is not displayed correctly, please click here to read this table of contents online. New Issue Alert 05/10/2016 Dear Alexandros Sfakianakis, We are pleased to deliver your requested table of contents alert for Journal of Behavioral Medicine. Volume 39 Number 3 is now available online. In this issue A synthesis of meta-analytic […]

Use of biologics for pustulotic arthro-osteitis in two patients with palmoplantar pustulosis

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1ZAjmIW via IFTTT

Molecular typing using polymorphisms of the polyketide synthase gene (PKS1) of strains in Japan morphologically identified as Fonsecaea pedrosoi

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Abstract *Fonsecaea pedrosoi* sensu lato is a major causative agent of dematiaceous fungal infection in Japan. Recent sequence analysis of the internal transcribed spacer (ITS) regions of the ribosomal RNA gene has shown that this species can be separated into three species: *F. pedrosoi* sensu stricto, *F. monophora* and *F. nubica*. The cell walls of dematiaceous fungi including the genus *Fonsecaea* contain melanin, which is important for their virulence. Polyketide synthase (PKS1) is an enzyme required for melanin synthesis. This study analyzed the phylogeny of strains of *F. ...περισσότερα »

Clinician Beliefs and Attitudes Regarding Use of Respiratory Protective Devices and Surgical Masks for Influenza.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Clinician Beliefs and Attitudes Regarding Use of Respiratory Protective Devices and Surgical Masks for Influenza.* Health Secur. 2015 Jul-Aug;13(4):274-80 Authors: Pillai SK, Beekmann SE, Babcock HM, Pavia AT, Koonin LM, Polgreen PM Abstract While influenza transmission is thought to occur primarily by droplet spread, the role of airborne spread remains uncertain. Understanding the beliefs and attitudes of infectious disease physicians regarding influenza transmission and respiratory and barrier protection preferences can provide insights into workplace decisio... περισσότερα »

The expression of B & T cell activation markers in children's tonsils following live attenuated influenza vaccine.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *The expression of B & T cell activation markers in children's tonsils following live attenuated influenza vaccine.* Hum Vaccin Immunother. 2015;11(7):1663-72 Authors: Panapasa JA, Cox RJ, Mohn KG, Aqrawi LA, Brokstad KA Abstract Live attenuated influenza vaccines (LAIV) can prevent influenza illness and death in children. The absence of known correlates of protection induced by LAIV requires human studies of underlying mechanisms of vaccine-induced immunity, to further elucidate the immu... περισσότερα »

Immunological persistence of a seasonal influenza vaccine in people more than 3 years old.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Immunological persistence of a seasonal influenza vaccine in people more than 3 years old.* Hum Vaccin Immunother. 2015;11(7):1648-53 Authors: Bai Y, Shi N, Lu Q, Yang L, Wang Z, Li L, Han H, Zheng D, Luo F, Zhang Z, Ai X Abstract To evaluate antibody persistence of Aleph inactivated split influenza vaccine, 3308 healthy Chinese people more than 3 years old were enrolled in a hemagglutination inhibition (HI) assay before vaccination, 641 were screened by HI assay negative, 437 of which received one dose of Aleph inactivated... περισσότερα »

Early estimates of 2014/15 seasonal influenza vaccine effectiveness in preventing influenza-like illness in general practice using the screening method in France.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Early estimates of 2014/15 seasonal influenza vaccine effectiveness in preventing influenza-like illness in general practice using the screening method in France.* Hum Vaccin Immunother. 2015;11(7):1621-5 Authors: Souty C, Blanchon T, Bonmarin I, Lévy-Bruhl D, Behillil S, Enouf V, Valette M, Bouscambert M, Turbelin C, Capai L, Roussel V, Hanslik T, Falchi A Abstract The ongoing influenza epidemic is characterized by intense activity with most influenza infections due to the A (H3N2) viruses. Using the screening method, mid-... περισσότερα »

Single dose vaccination of the ASO3-adjuvanted A(H1N1)pdm09 monovalent vaccine in health care workers elicits homologous and cross-reactive cellular and humoral responses to H1N1 strains.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Single dose vaccination of the ASO3-adjuvanted A(H1N1)pdm09 monovalent vaccine in health care workers elicits homologous and cross-reactive cellular and humoral responses to H1N1 strains.* Hum Vaccin Immunother. 2015;11(7):1654-62 Authors: Lartey S, Pathirana RD, Zhou F, Jul-Larsen Å, Montomoli E, Wood J, Cox RJ Abstract Healthcare workers (HCW) were prioritized for vaccination during the 2009 influenza A(H1N1)pdm09 pandemic. We conducted a clinical trial in October 2009 where 237 HCWs ... περισσότερα »

Influence of sources of information about influenza vaccine on parental attitudes and adolescent vaccine receipt.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Influence of sources of information about influenza vaccine on parental attitudes and adolescent vaccine receipt.* Hum Vaccin Immunother. 2015;11(7):1641-7 Authors: Gargano LM, Underwood NL, Sales JM, Seib K, Morfaw C, Murray D, DiClemente RJ, Hughes JM Abstract In 2011-2012, only 34% of 13-17 years olds in the United States (US) received seasonal influenza vaccine. Little is known about the link between parents' sources of health information, their vaccine-related attitudes, and vaccination of their adolescent against influ... περισσότερα »

Influenza vaccine effectiveness in preventing inpatient and outpatient cases in a season dominated by vaccine-matched influenza B virus.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Influenza vaccine effectiveness in preventing inpatient and outpatient cases in a season dominated by vaccine-matched influenza B virus.* Hum Vaccin Immunother. 2015;11(7):1626-33 Authors: Martínez-Baz I, Navascués A, Pozo F, Chamorro J, Albeniz E, Casado I, Reina G, Cenoz MG, Ezpeleta C, Castilla J, Primary Health Care Sentinel Network and Network for Influenza Surveillance in Hospitals of Navarra Abstract Studies that have evaluated the influenza vaccine effectiveness (VE) to prevent laboratory-confirmed influenza B cases a... περισσότερα »

Human papillomavirus vaccination among adolescents in Georgia.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Human papillomavirus vaccination among adolescents in Georgia.* Hum Vaccin Immunother. 2015;11(7):1703-8 Authors: Underwood NL, Weiss P, Gargano LM, Seib K, Rask KJ, Morfaw C, Murray D, DiClemente RJ, Hughes JM, Sales JM Abstract Human papillomavirus (HPV) vaccination coverage for adolescent females and males remains low in the United States. We conducted a 3-arm randomized controlled trial (RCT) conducted in middle and high schools in eastern Georgia from 2011-2013 to determine the effe... περισσότερα »

Oral drugs in the treatment of metastatic colorectal cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Oral drugs in the treatment of metastatic colorectal cancer.* Expert Opin Pharmacother. 2016 May 9; Authors: Kwakman JJ, Punt CJ Abstract INTRODUCTION: Intravenous administration of fluoropyrimidine-based chemotherapy has been the cornerstone of treatment in metastatic colorectal cancer (mCRC) for decades. The availability of oral capecitabine has improved the tolerability in monotherapy schedules, and has simplified combination schedules. Since then, other oral drugs have proven efficacy in this setting. Areas covered: We review the available evidence and most recent data conce...περισσότερα »

How will the MMR universal mass vaccination change the epidemiologic pattern of mumps? A 2012 Italian serosurvey.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*How will the MMR universal mass vaccination change the epidemiologic pattern of mumps? A 2012 Italian serosurvey.* Am J Infect Control. 2016 May 2; Authors: Tafuri S, Gallone MS, Larocca AM, Germinario C Abstract To investigate the changes in the epidemiologic pattern of mumps, we carried out a serosurvey among young adults from Apulia, Italy. A convenience sample of 1,764 blood donors were enrolled in 2012: 93.4% (95% confidence interval, 92.1-94.5) showed a positive antimumps immunoglobulin G titre, geometric mean titer was 2.05. Results were consistent with previously publish...περισσότερα »

miR-199a and miR-497 Are Associated with Better Overall Survival due to Increased Chemosensitivity in Diffuse Large B-Cell Lymphoma Patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *miR-199a and miR-497 Are Associated with Better Overall Survival due to Increased Chemosensitivity in Diffuse Large B-Cell Lymphoma Patients.* Int J Mol Sci. 2015;16(8):18077-95 Authors: Troppan K, Wenzl K, Pichler M, Pursche B, Schwarzenbacher D, Feichtinger J, Thallinger GG, Beham-Schmid C, Neumeister P, Deutsch A Abstract Micro-RNAs (miRNAs) are short non-coding single-stranded RNA molecules regulating gene expression at the post-transcriptional level. miRNAs are involved in cell development, differentiation, apoptosis, and... περισσότερα »

Vaccine immunotherapy in lung cancer: Clinical experience and future directions.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Vaccine immunotherapy in lung cancer: Clinical experience and future directions.* Pharmacol Ther. 2015 Sep;153:1-9 Authors: Freeman-Keller M, Goldman J, Gray J Abstract Lung cancer remains the most common cause of cancer-related deaths in the United States, with SEER data showing lung cancer accounting for 29% of all male-related cancer mortality and 26% of all female-related mortality. Patients with small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) who have localized disease both have 5-year su... περισσότερα »

In Search of a Gold Standard Scoring System for the Subjective Evaluation of Cosmetic Outcomes Following Breast-Conserving Therapy.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *In Search of a Gold Standard Scoring System for the Subjective Evaluation of Cosmetic Outcomes Following Breast-Conserving Therapy.* Breast J. 2015 Jul-Aug;21(4):345-51 Authors: Racz JM, Hong NL, Latosinsky S Abstract The absence of a widely accepted method for aesthetic evaluation following breast-conserving surgery for breast cancer limits the ability to evaluate cosmetic outcomes. In this study, two different panel scoring approaches were compared in an attempt to identify a gold standard scoring system for sub... περισσότερα »

Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile.* Cell Cycle. 2014;13(7):1132-44 Authors: Oliveras-Ferraros C, Vazquez-Martin A, Cuyàs E, Corominas-Faja B, Rodríguez-Gallego E, Fernández-Arroyo S, Martin-Castillo B, Joven J, Menendez JA Abstract Therapeutic interventions based on metabolic inhibitor-based therapies are expected to be less prone to acquired resistance. However, there has n... περισσότερα »

Resection and microvascular reconstruction of bisphosphonate-related osteonecrosis of the jaw: The role of microvascular reconstruction.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Resection and microvascular reconstruction of bisphosphonate-related osteonecrosis of the jaw: The role of microvascular reconstruction.* Head Neck. 2016 May 9; Authors: Neto T, Horta R, Balhau R, Coelho L, Silva P, Correia-Sá I, Silva Á Abstract BACKGROUND: Current treatment guidelines caution against osseous reconstruction using free flap tissue to treat bisphosphonate-related osteonecrosis of the jaw (BRONJ). The primary rationale for this stance is the theoretical risk of nonunion and recurrence of disease within the reconstruction. Emerging evidence suggests that these theor... περισσότερα »

Upper Respiratory Tract Infections

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
67 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2016/05/10 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 2 via ola Kala on Inoreader http://ift.tt/23EftDN via IFTTT

Characterization of a PTH1R missense mutation responsible for Jansen type metaphyseal chondrodysplasia

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Parathyroid hormone and parathyroid hormone-related peptide (PTHrP), and its receptor (PTH1R) play an important role in differentiation of bone and cartilage in the developing stages. Constitutive dimers of PTH1R are believed to be dissociated by ligand binding, and monomeric PTH1R is capable of activating G protein. Jansen type metaphyseal chondrodysplasia is caused by missense mutations in PTH1R, which are constitutively active even without the presence of the ligands. However, the underlying pathomechanisms remained largely unknown. In this study, we have attempted to f...περισσότερα »

Poor dental hygiene and periodontal health in nursing home residents with dementia: an observational study

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Poor oral health conditions are well documented in the institutionalized elderly, but the literature is lacking research on relationships between dementia and periodontal health in nursing home residents. The purpose of this cohort study, therefore, was to assess whether dementia is associated with poor oral health/denture hygiene and an increased risk of periodontal disease in the institutionalized elderly. A total of 219 participants were assessed using the Mini Mental State Examination (MMSE) to determine cognitive state. According to the MMSE outcome, participants scori... περισσότερα »

Dentoskeletal effects produced by removable palatal crib, bonded spurs, and chincup therapy in growing children with anterior open bite

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
The Angle Orthodontist, Ahead of Print. from #Dental via xlomafota13 on Inoreader http://ift.tt/1T2KYCw via IFTTT

Liver failure complicating a febrile illness in a middle-aged man

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Gastroenterology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OlqPpg via IFTTT

Preinjury somatization symptoms contribute to clinical recovery after sport-related concussion

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Neurology® from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NpcxJu via IFTTT

Ingredient in anti-diarrhea medication used to self-treat opioid addiction with dangerous results, Upstate Poison Center study shows

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Upstate Medical University News from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OlqPpe via IFTTT

Epstein-Barr Virus-Induced Gene 3 (EBI3) Blocking Leads to Induce Antitumor Cytotoxic T Lymphocyte Response and Suppress Tumor Growth in Colorectal Cancer by Bidirectional Reciprocal-Regulation STAT3 Signaling Pathway

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 1 ώρα
Epstein-Barr virus-induced gene 3 (EBI3) is a member of the interleukin-12 (IL-12) family structural subunit and can form a heterodimer with IL-27p28 and IL-12p35 subunit to build IL-27 and IL-35, respectively. However, IL-27 stimulates whereas IL-35 inhibits antitumor T cell responses. To date, little is known about the role of EBI3 in tumor microenvironment. In this study, firstly we assessed EBI3, IL-27p28, IL-12p35, gp130, and p-STAT3 expression with clinicopathological parameters of colorectal cancer (CRC) tissues; then we evaluated the antitumor T cell responses and tumor gro... περισσότερα »

Dosimetric advantages of intensity-modulated proton therapy for oropharyngeal cancer compared with intensity-modulated radiation: A case-matched control analysis.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Dosimetric advantages of intensity-modulated proton therapy for oropharyngeal cancer compared with intensity-modulated radiation: A case-matched control analysis.* Med Dosim. 2016 May 3; Authors: Holliday EB, Kocak-Uzel E, Feng L, Thaker NG, Blanchard P, Rosenthal DI, Gunn GB, Garden AS, Frank SJ Abstract A potential advantage of intensity-modulated proton therapy (IMPT) over intensity-modulated (photon) radiation therapy (IMRT) in the treatment of oropharyngeal carcinoma (OPC) is lower radiation dose to several critical structures involved in the development of nausea and vomit...περισσότερα »

[The Significance of Resection of the Cricoid Cartilage as a Surgical Procedure in Laryngotracheal Surgery].

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
Related Articles *[The Significance of Resection of the Cricoid Cartilage as a Surgical Procedure in Laryngotracheal Surgery].* Nihon Jibiinkoka Gakkai Kaiho. 2015 Oct;118(10):1233-40 Authors: Hirai T, Fukushima N, Kano M, Miyahara N, Miyoshi A, Ariki M, Masuda S, Nagamine H Abstract The cricoid cartilage has been regarded as an extremely important organ because it plays important role in both of phonation and breathing. We herein report on two different types of surgical procedure for laryngotracheal diseases with aggressive resection of the cricoid cartilage. The first procedu... περισσότερα »

Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
[image: http:--http://ift.tt/1feGv2I] Related Articles *Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells.* Cell Death Differ. 2015 Nov;22(11):1865-76 Authors: Stedman A, Beck-Cormier S, Le Bouteiller M, Raveux A, Vandormael-Pournin S, Coqueran S, Lejour V, Jarzebowski L, Toledo F, Robine S, Cohen-Tannoudji M Abstract Ribosome biogenesis is an essential cellular process. Its impairment is associated with developmental defects and increased risk of cancer. The in vivo cellular responses to defe... περισσότερα »

Effect of three levels of dietary protein on metabolic phenotype of healthy individuals with 8 weeks of overfeeding.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Effect of three levels of dietary protein on metabolic phenotype of healthy individuals with 8 weeks of overfeeding.* J Clin Endocrinol Metab. 2016 May 9;:jc20161313 Authors: Bray GA, Redman LM, de Jonge L, Rood J, Smith SR Abstract CONTEXT: Obesity is associated with insulin resistance and other metabolic changes which might be modified by overfeeding diets with different protein levels. OBJECTIVE: To determine the effect of overfeeding diets with 5%, 15% or 25% energy from protein on insulin sensitivity and compartments of body fat in healthy men and women. METHODS: 15 men and ... περισσότερα »

IMBALANCE OF AMNIOTIC FLUID ACTIVIN-A AND FOLLISTATIN IN INTRA-AMNIOTIC INFECTION, INFLAMMATION AND PRETERM BIRTH.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*IMBALANCE OF AMNIOTIC FLUID ACTIVIN-A AND FOLLISTATIN IN INTRA-AMNIOTIC INFECTION, INFLAMMATION AND PRETERM BIRTH.* J Clin Endocrinol Metab. 2016 May 9;:jc20154147 Authors: Hardy JT, Buhimschi IA, McCarthy ME, Zhao G, Laky CA, Shook LL, Buhimschi CS Abstract CONTEXT: Microbial invasion of amniotic fluid (AF) cavity stimulates an inflammatory response that involves activin-A, a pleiotropic mediator member of TGFβ superfamily involved in connective tissue remodeling. The role of AF follistatin, a natural inhibitor of activin-A, in inflammationinduced preterm birth (PTB) has yet to... περισσότερα »

Pre-pregnancy factors as determinants of the development of diabetes mellitus after first pregnancy.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Pre-pregnancy factors as determinants of the development of diabetes mellitus after first pregnancy.* J Clin Endocrinol Metab. 2016 May 9;:jc20153761 Authors: Joon Cho G, Heon Park J, Lee H, Yoo S, Shin SA, Oh MJ Abstract CONTEXT: The identification of modifiable factors at pre-pregnancy or early pregnancy as well as continued monitoring and management of these factors before and during pregnancy may reduce the incidence of diabetes mellitus (DM) among women, regardless of gestational diabetes mellitus (GDM) status. OBJECTIVE: This study aimed to identify pre-pregnancy factors for... περισσότερα »

An audit of CT chest surveillance following oral cancer treatment.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*An audit of CT chest surveillance following oral cancer treatment.* Br J Oral Maxillofac Surg. 2016 May 3; Authors: Nugent G, Hughes T, Hanlon R, Jones HL, Rogers SN Abstract Computed tomography (CT) of the chest is an integral part of the staging of patients with oral cancer. It identifies metastases, synchronous pulmonary primaries, and detects small nodules of indeterminate character that require a follow-up scan. We aimed to find out how many patients with small nodules had had subsequent scans, and the outcome of those who did. Between 2010 and 2013, 413 patients with oral s... περισσότερα »

Laryngeal Neuroendocrine Carcinomas: A Retrospective Study of 14 Cases.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--images.hindawi.com-linkout-hindaw] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Laryngeal Neuroendocrine Carcinomas: A Retrospective Study of 14 Cases.* Biomed Res Int. 2015;2015:832194 Authors: Zhu Y, Gao L, Meng Y, Diao W, Zhu X, Li G, Gao Z, Chen X Abstract Laryngeal neuroendocrine carcinomas (LNECs) are rare and highly heterogeneous which present a wide spectrum of pathological and clinical manifestations. Fourteen patients with histologically demonstrated LNEC were collected and analyzed retrospectively. The 14 cases were classified into 3 subtypes:... περισσότερα »

Cordycepin inhibits LPS-induced inflammatory and matrix degradation in the intervertebral disc

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: fig-1-1x.jpg] Cordycepin is a component of the extract obtained from Cordyceps militaris and has many biological activities, including anti-cancer, anti-metastatic and anti-inflammatory effects. Intervertebral disc degeneration (IDD) is a degenerative disease that is closely related to the inflammation of nucleus pulposus (NP) cells. The effect of cordycepin on NP cells in relation to inflammation and degeneration has not yet been studied. In our study, we used a rat NP cell culture and an intervertebral disc (IVD) organ culture model to examine the inhibitory effects of co... περισσότερα »

Journal of Behavioral Medicine, Vol. 39, Issue 3 - New Issue Alert

Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 1 ώρα
If this email is not displayed correctly, please click here to read this table of contents online. New Issue Alert 05/10/2016 Dear Alexandros Sfakianakis, We are pleased to deliver your requested table of contents alert for *Journal of Behavioral Medicine*. Volume 39 Number 3 is now available online. In this issue A synthesis of meta-analytic evidence of behavioral interventions to reduce HIV/STIs Judith Covey, Harriet E. S. Rosenthal-Stott & Stephanie J. Howell » Abstract » Full text HTML » Full text PDF Sleep and health-related factors in overweight and obese rural wo... περισσότερα »

Feasibility and Advantage of a Muscle-Sparing Laterally Based Pericranial Flap.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Feasibility and Advantage of a Muscle-Sparing Laterally Based Pericranial Flap.* J Craniofac Surg. 2016 May;27(3):552-557 Authors: Yano T, Okazaki M, Tanaka K, Tsunoda A, Aoyagi M, Kishimoto S Abstract BACKGROUND: For a safe and reliable middle skull base reconstruction, the temporalis muscle flaps or pericranial-temporalis muscle flaps have usually been used as the first-choice in clinical practice. But these flaps have an inevitable disadvantage, namely, temporal hollowing. To address this problem, in this study, the authors describe the feasibility and advantages of using a m...περισσότερα »

Comparative diagnostic value of 18F-fluoride PET-CT versus MRI for skull-base bone invasion in nasopharyngeal carcinoma.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Comparative diagnostic value of 18F-fluoride PET-CT versus MRI for skull-base bone invasion in nasopharyngeal carcinoma.* Nucl Med Commun. 2016 May 6; Authors: Le Y, Chen Y, Zhou F, Liu G, Huang Z, Chen Y Abstract PURPOSE: This study compared the diagnostic value of F-fluoride PET-computed tomography (PET-CT) and MRI in skull-base bone erosion in nasopharyngeal carcinoma (NPC) patients. METHODS: A total of 93 patients with biopsy-confirmed NPC were enrolled, including 68 men and 25 women between 23 and 74 years of age. All patients were evaluated by both F-fluoride PET-CT and MRI... περισσότερα »

Outcomes of complete vs targeted approaches to endoscopic sinus surgery.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Outcomes of complete vs targeted approaches to endoscopic sinus surgery.* Int Forum Allergy Rhinol. 2015 Aug;5(8):691-700 Authors: DeConde AS, Suh JD, Mace JC, Alt JA, Smith TL Abstract BACKGROUND: Functional endoscopic sinus surgery (FESS) was historically predicated on targeted widening of narrow anatomic structures that caused postobstructive persistent sinus inflammation. It is now clear that chronic rhinosinusitis (CRS) is a multifactorial disease with subsets of patients which may require a more extensive su... περισσότερα »

Advanced Diagnostic Genetic Testing In Inherited Retinal Disease:Experience from a Single Tertiary Referral Centre in the UK National Health Service

Alexandros G. SfakianakisστοEvolution of a geneΠριν από 1 ώρα
ABSTRACT Background/Aims In 2013, as part of our genetic investigation of patients with Inherited Retinal Disease, we utilised multigene panel testing of 105 genes known to cause retinal disease in our patient cohorts. This test was performed in a UK National Health Service (NHS) accredited laboratory. Method The results of all multigene panel tests requested between 1.4.13 and 31.8.14 were retrospectively reviewed. All patients had been previously seen at Moorfields Eye Hospital, London, UK and diagnosed with an inherited retinal dystrophy after clinical examination and detailed... περισσότερα »

Hyaluronic Acid Molecular Weight Determines Lung Clearance and Biodistribution after Instillation.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Hyaluronic Acid Molecular Weight Determines Lung Clearance and Biodistribution after Instillation.* Mol Pharm. 2016 May 9; Authors: Kuehl C, Zhang T, Kaminskas LM, Porter CJ, Davies NM, Forrest ML, Berkland CJ Abstract Hyaluronic acid (HA) has emerged as a versatile polymer for drug delivery. Multiple commercial products utilize HA, it can be obtained in a variety of molecular weights, and it offers chemical handles for crosslinkers, drugs, or imaging agents. Previous studies have investigated multiple administration routes, but the absorption, biodistribution, and pharmacokine... περισσότερα »

The Feasibility and Utility of Continuous Sleep Monitoring in Critically Ill Patients Using a Portable Electroencephalography Monitor.

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 1 ώρα
BACKGROUND: Sleep disruption in critically ill adults can result in acute decrements in cognitive function, including delirium, but it is underdiagnosed in the setting of the intensive care unit (ICU). Although sleep stages can be assessed by polysomnography (PSG), acquisition and interpretation of PSG is costly, is labor intensive, is difficult to do over an extended period of time with critically ill patients (multiple days of continuous recording), and may interfere with patient care. In this pilot study, we investigated the feasibility and utility of monitoring sleep in the ICU ... περισσότερα »

Neuraxial Anesthesia in Parturients with Low Platelet Counts.

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 1 ώρα
The obstetric anesthesiologist must consider the risk of spinal-epidural hematoma in patients with thrombocytopenia when choosing to provide neuraxial anesthesia. There are little data exploring this complication in the parturient. In this single-center retrospective study of 20,244 obstetric patients, the incidence of peripartum thrombocytopenia (platelet count from Anaesthesia via ola Kala on Inoreader http://ift.tt/1T0JtZ1 via IFTTT

Resection and microvascular reconstruction of bisphosphonate-related osteonecrosis of the jaw: The role of microvascular reconstruction.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Resection and microvascular reconstruction of bisphosphonate-related osteonecrosis of the jaw: The role of microvascular reconstruction.* Head Neck. 2016 May 9; Authors: Neto T, Horta R, Balhau R, Coelho L, Silva P, Correia-Sá I, Silva Á Abstract BACKGROUND: Current treatment guidelines caution against osseous reconstruction using free flap tissue to treat bisphosphonate-related osteonecrosis of the jaw (BRONJ). The primary rationale for this stance is the theoretical risk of nonunion and recurrence of disease within the reconstruction. Emerging evidence suggests that these theor... περισσότερα »