Australasian Journal of Dermatology, EarlyView.
https://ift.tt/2LScJ3I
Κυριακή 2 Σεπτεμβρίου 2018
Mycobacterium abscessus infection following penetrations through wetsuits
Adjuvant treatment of chronic plaque psoriasis in adults by a herbal combination: Open German trial and review of the literature
Dermatologic Therapy, EarlyView.
https://ift.tt/2LQDiXb
Sudanese Association of Dermatologists Special Meeting, Khartoum, Sudan
Dermatologic Therapy, EarlyView.
https://ift.tt/2wBkWEG
Common allergies in urban adolescents and their relationships with asthma control and healthcare utilization
Urban adolescents suffer a disproportionate burden of asthma morbidity, often in association with allergies. Literature is limited on comparing various types of allergies regarding prevalence and associations ...
https://ift.tt/2PXRUXX
Hemolysis induced cross-matching difficulty with intravenous immunoglobulin: a case report
Intravenous immunoglobulin is one of the most common modalities of treatment for Guillain–Barré syndrome. Although minor complications are easily preventable with pre-medications, rare complications like hemol...
https://ift.tt/2NCXrS6
The use of a skin-stretching device combined with vacuum sealing drainage for closure of a large skin defect: a case report
This case report presents the treatment of a large infected skin defect, which was caused by an accidental explosion, through a skin-stretching device combined with vacuum sealing drainage. To the best of our ...
https://ift.tt/2Nceg9v
Ertapenem for the treatment of Hidradenitis suppurativa: how much do we need it?
Prevention and treatment of tuberculosis infection in candidates for biologic therapy: A multidisciplinary consensus statement adapted to the dermatology patient
P. Rodríguez-Jiménez, I. Mir-Viladrich, P. Chicharro, G. Solano-López, F.J. López-Longo, C. Taxonera, P. Sánchez-Martínez, X. Martínez-Lacasa, M. García-Gasalla, J. Dorca, M. Arias-Guillén, J.M. García-García, E. Dauden
Actas Dermosifiliogr.2018;109:584-601
Abstract - Full text - PDF
https://ift.tt/2oA1tj6
Allergic Contact Dermatitis Due to Paraphenylenediamine: An Update
The First Year of the AEVD Primary Cutaneous Lymphoma Registry
Y. Peñate, O. Servitje, S. Machan, R. Fernández-de-Misa, M.T. Estrach, E. Acebo, J. Mitxelena, M.D. Ramón, A. Flórez, M. Blanes, M. Morillo, S. Medina, J. Bassas, A. Zayas, P. Espinosa, A. Pérez, N. Gónzalez-Romero, J.D. Domínguez, C. Muniesa, J. López Robles, A. Combalia, I. Yanguas, H. Suh, I. Polo-Rodríguez, I. Bielsa, A. Mateu, B. Ferrer, M.A. Descalzo, I. García-Doval, P.L. Ortiz-Romero
Actas Dermosifiliogr.2018;109:610-6
Abstract - Full text - PDF
https://ift.tt/2oxKWMD
Description of Patients Treated with Biologic Drugs as First-Line Systemic Therapy in the BIOBADADERM Registry Between 2008 and 2016
G. Carretero Hernández, C. Ferrándiz, R. Rivera Díaz, E. Daudén Tello, P. de la Cueva-Dobao, F.J. Gómez-García, E. Herrera-Ceballos, I. Belinchón Romero, J.L. López-Estebaranz, M. Alsina Gibert, J.L. Sánchez-Carazo, M. Ferrán Farrés, A. González Quesada, J.M. Carrascosa Carrillo, M. Llamas-Velasco, M.V. Mendiola Fernández, D. Ruiz Genao, C. Muñoz Santos, I. García-Doval, M.A. Descalzo
Actas Dermosifiliogr.2018;109:617-23
Abstract - Full text - PDF
https://ift.tt/2CdDeB2
Practice Models in Teledermatology in Spain: Longitudinal Study, 2009-2014
Management of Moderate to Severe Psoriasis in Routine Clinical Practice in Spanish Hospitals
Idiopathic Facial Aseptic Granuloma: Clinical and Ultrasound Findings in 3 Cases
Pityriasis Lichenoides et Varioliformis Acuta Associated With Human Herpesvirus 7
Ulcerated Penile Lesion
Máculas evanescentes en tronco y extremidades
Tumor Collision Over Sebaceous Nevus: Clues for Dermoscopic Diagnosis
Quality of Life in Nonmelanoma Skin Cancer
Rare Tongue Compromising of Mucocutaneous Leishmaniasis by Leishmania Subgenus Viannia
Cervical Cellulitis of Odontogenic Origin
Agminated Dermal Melanocytosis in the Territory of Ota's Nevus
Enfermedad de Rosai-Dorfman cutánea: una nueva presentación clínica
A Wilms’ Tumor with Spinal Cord Compression: An Extrarenal Origin?
Spinal cord compression in Wilms' tumor (WT) is an extremely rare event that can have a very poor prognosis if not taken care of rapidly. Most cases reported in the literature involve widely metastatic patient with bone or paraspinal metastases or occasionally intradural metastasis. Here, we present the case of a 3-year-old girl of WT confirmed by biopsy, with spinal cord compression due to the direct contiguous spread of a tumor through 2 vertebral foramina. Abdominal ultrasonography and magnetic resonance imaging performed for an abdominal mass revealed a large heterogeneous tumor near the upper pole of the left kidney. A nodular infiltration extended through the T11-L1 and L1-L2 neural foramina, forming an intraspinal mass that compressed the spinal cord. Major paresthesia subsequently occurred, requiring urgent treatment with corticosteroids and chemotherapy. The evolution was rapidly satisfying. After six courses of chemotherapy, a left nephrectomy was performed. Macroscopic examination identified a large tumor attached to the kidney without renal infiltration. Microscopical examination concluded to a nephroblastoma with regressive changes, of intermediate risk. Evolution at 6 months is satisfactory, with no neurological deficit. The histological aspect of the tumor and the clinical outcome suggest that she had an extrarenal WT that spread through the vertebral foramina and was secondarily attached to the kidney.
https://ift.tt/2PA5pfB
Issue Information
The Journal of Dermatology, Volume 45, Issue 9, Page 1147-1147, September 2018.
https://ift.tt/2ozlAxY
Possible contribution of autophagy in pyogenic granuloma
The Journal of Dermatology, Volume 45, Issue 9, Page 1145-1146, September 2018.
https://ift.tt/2Pxrjju
Issue Information
The Journal of Dermatology, Volume 45, Issue 9, Page i, 1029-1030, September 2018.
https://ift.tt/2ozHZLL
Kératodermie acrale symétrique : responsabilité de mutations d’un facteur de transcription
Publication date: Available online 1 September 2018
Source: Annales de Dermatologie et de Vénéréologie
Author(s): O. Dereure
https://ift.tt/2wvICKH
Early auditory skills development in Mandarin speaking Children after bilateral cochlear implantation
Publication date: Available online 1 September 2018
Source: International Journal of Pediatric Otorhinolaryngology
Author(s): Yue Long, Haihong Liu, Ying Li, Xin Jin, Yi Zhou, Jing Li, Zhipeng Zheng, Peng Liu, Yawen Zhao, Jun Zheng, Jie Zhang, Min Chen, Jinsheng Hao, Yang Yang, Wei Liu
Abstract
Objectives
The purpose of the present study was: (1) to investigate the early auditory preverbal behaviors of infants/toddlers with bilateral cochlear implants (BCI), and to compare their performance with that of unilateral cochlear implant (UCI) peers; (2) to investigate effects of age of implantation, education level of caregivers, living environment, and unaided behavioral threshold before operation on early auditory preverbal development.
Methods
The evaluation material of the present study was the Mandarin version of the LittlEARS® Auditory Questionnaire (LEAQ). Assessments were administrated at 0, 1, 2, 3, 6, 9, 12 and 24 months after cochlear implants (CIs) were switched on. A one-way ANOVA was used to analyze the differences of early auditory preverbal performance between each two contiguous test intervals. A two-sample t test was used to analyze the difference of behaviors between infants/toddlers with BCI and UCI. Non-parametric tests were used to analyze the effects of potential affecting factors on auditory preverbal skills.
Results
Nineteen subjects aging from 9 to 54 months (Mean=22.7, SD=13.7) were recruited in the study. At each evaluation time, the average scores of LEAQ were 4.58, 9.00, 16.00, 18.56, 22.00, 31.50, 29.67, and 34.35 respectively. The total score and semantic auditory behavior score increased significantly during the second months after CIs activation (the total score: LSD-t=3.157, p=0.030; semantic auditory behavior score: LSD-t=1.972, p=0.034). The score of BCI group was significantly higher than UCI group after 1, 3 and 6 months of CI use (1 month: t=3.257, p=0.002; 3 months: t=5.042, p=0.000, 6 months: t=4.054, p=0.000). Education level of caregivers had a positive effect on receptive auditory behavior (H=6.538, p=0.035) after CIs switched on for 3 months. The LEAQ performance was not significantly correlated with pre-operative behavioral threshold although they showed a trend of negative correlation in the first 3 months after activation.
Conclusion
The study indicated that infants and toddlers who underwent BCI had better auditory preverbal skills than their UCI peers. Higher caregivers' education level positively correlated with the early development of auditory preverbal skills. Better pre-operative behavioral threshold might also benefit early auditory preverbal skills development for BCI children.
https://ift.tt/2Nc0R18
A Multidisciplinary International Collaborative Implementing Low Cost, High Fidelity 3D Printed Airway Models To Enhance Ethiopian Anesthesia Resident Emergency Cricothyroidotomy Skills
Publication date: Available online 1 September 2018
Source: International Journal of Pediatric Otorhinolaryngology
Author(s): Virginia T. Gauger, Deborah Rooney, Kevin J. Kovatch, Lauren Richey, Allison Powell, Hailesllassie Berhe, David A. Zopf
Abstract
Background
Similar to other sub-Saharan countries, Ethiopia suffers from a severe shortage of adequately trained health professionals. Academic partnerships can support sustainable training programs and build capacity for low-resource settings. 3D modeling and simulation-based training provide necessary tools, especially for rarely-encountered clinical situations, such as needle cricothyroidotomy.
Methods
Departments of Anesthesiology, Otolaryngology, and Learning Health Sciences collaborated to develop a low-cost, high-fidelity simulator and Cricothryoidotomy Skills Maintenance Program (CSMP). Twelve anesthesia residents at St. Paul's Hospital Medical Millennium College in Addis Ababa, Ethiopia participated in CSMP. The program consisted of a didactic session with presentation and demonstration and an immersive CICO scenario. Program evaluation was performed using pre/post-training knowledge and 2 procedural performance assessments-the CSMP Global Rating Scale and the Checklist. With consent, performances were videotaped and rated independently by 3 University of Michigan faculty.
Results
Improvements were identified in all areas, including residents' knowledge, measured by mean summed test scores, (Mpre=3.31,Mpost=4.46, p=0.003), time to perform cricothyroidotomy (Mpre=96.64,Mpost=72.82,p=0.12), residents' performance quality, measured by overall mean Global ratings, (Mpre=0.20;Mpost=0.70) with improvements identified at the item-level, p=0.001 with moderate-large effect sizes, and residents' ability to complete tasks, measured by mean Checklist ratings (Mpre=0.51,Mpost=0.90, with item-level improvements observed, p≤0.01, with small-large effect sizes. Residents' self-reported confidence also improved, (Mpre=1.69, Mpost=3.08,p=0.001.
Conclusion
Our work shows that cricothyroidotomy skills taught to anesthesia residents at SPHMMC with a 3D printed laryngotracheal model improves knowledge, skills, and confidence. The creation of a low-cost, high-fidelity simulator and a CSMP has the potential to impact patient care and safety world-wide.
https://ift.tt/2CbfTA6
Volumetric changes of the upper airway following maxillary and mandibular advancement using cone beam computed tomography
Publication date: Available online 1 September 2018
Source: International Journal of Oral and Maxillofacial Surgery
Author(s): G.K. Parsi, A.A. Alsulaiman, B. Kotak, P. Mehra, L.A. Will, M. Motro
Abstract
The objective of this project was to retrospectively evaluate changes in volume of different compartments of the upper airway in response to maxillary, mandibular, and bimaxillary advancement surgeries and to predict the extent of volumetric changes associated with these surgical movements. Pre- and post-surgical cone beam computed tomography scans of 36 patients were evaluated for changes in nasal cavity, nasopharyngeal, oropharyngeal, and hypopharyngeal compartments. The amount of movement for each surgery was measured from skeletal landmarks to reference planes and was correlated with volumetric changes. Maxillary advancement of 4.0 ± 2.2 mm increased the oropharyngeal volume significantly (41.40%), and mandibular advancement of 3.8 ± 1.6 mm also significantly increased the oropharyngeal volume (21.17%). Bimaxillary advancement of 5.1 ± 1.3 mm for the maxilla and 6.4 ± 3.1 mm for the mandible significantly increased nasopharyngeal (27.45%), oropharyngeal (66.39%), and hypopharyngeal (52.48%) volumes. Furthermore, for every millimeter anterior movement, oropharyngeal volume increased by 2319.2 ± 771.8 mm3. Bimaxillary advancement showed a greater increase than isolated maxillary and mandibular advancement in all pharyngeal compartments. Every millimeter of advancement in the bimaxillary group led to a significant increase in oropharyngeal volume, while every millimeter downward movement showed a significant increase in nasopharyngeal volume.
https://ift.tt/2MFTy2q
House dust mite‐driven neutrophilic airway inflammation in mice with TNFAIP3‐deficient myeloid cells is IL‐17‐independent
Clinical &Experimental Allergy, Volume 0, Issue ja, -Not available-.
https://ift.tt/2NFcRFB
Neutrophils induce smooth muscle hyperplasia via neutrophil elastase–induced FGF‐2 in a mouse model of asthma with mixed inflammation
Clinical &Experimental Allergy, Volume 0, Issue ja, -Not available-.
https://ift.tt/2oyOIWe
Sweat is a most efficient natural moisturizer providing protective immunity at points of allergen entry
Publication date: Available online 1 September 2018
Source: Allergology International
Author(s): Tetsuo Shiohara, Yoshiko Mizukawa, Yurie Shimoda-Komatsu, Yumi Aoyama
Abstract
Although there is a growing acceptance that sweat could play a detrimental role in various allergic skin diseases, the possibility that sweat is also involved in maintenance of skin hydration and skin-specific immune responses has not been acknowledged. We initially describe physiological role of sweat in both maintaining skin hydration and thermoregulation. The purpose of this article is to provide the reader with objective evidence that sweating is intimately linked to vital stratum corneum barrier function and usefulness of application of moisturizers in clinical care of allergic skin diseases. This review also covers how sweating disturbance would leave the skin vulnerable to the development of various allergic skin diseases, such as atopic dermatitis. New therapeutic approaches would specifically target such sweating disturbance in these allergic skin diseases.
https://ift.tt/2oyis5K
A case of human seminal plasma allergy sensitized with dog prostatic kallikrein, Can f 5
Publication date: Available online 1 September 2018
Source: Allergology International
Author(s): Mari Tanaka, Yukinobu Nakagawa, Yorihisa Kotobuki, Ichiro Katayama
https://ift.tt/2Psvf4K
Differential Cellular Composition of Human Palatine and Pharyngeal Tonsils
Publication date: Available online 1 September 2018
Source: Archives of Oral Biology
Author(s): Luke Stanisce, Etty Sims, Cheryl Hou, Yekaterina Koshkareva, John P. Gaughan, Igor Kuzin, Andrea Bottaro
Abstract
Objective
The goal of this study was to gain a better understanding of the potential functional specialization of palatine and pharyngeal tonsils, by comparing their cellular composition in paired specimens from a large cohort of adenotonsillectomy patients.
Design
Resident B cell, T cell, dendritic cell, and stromal cell subsets were characterized using multicolor flow cytometry in palatine and pharyngeal tonsil specimens from 27 patients, age 2-34 years.
Results
Paired comparisons showed highly significant intra-individual differences in resident cell subsets of palatine and pharyngeal tonsils. Palatine tonsils harbored higher fractions of germinal center B cells/plasmablasts and IgD- CD27- double-negative B cells, and conversely lower fractions of IgD + CD38- resting naïve B cells compared to pharyngeal tonsils. Palatine tonsils also showed lower fractions of plasmacytoid dendritic cells, and higher percentages of two subsets of stromal cells - fibroblastic reticular cells and lymphatic endothelial cells - compared to pharyngeal tonsils from the same individual.
Conclusions
Despite their physical proximity and histological similarities, palatine and pharyngeal tonsils display marked intra-individual differences in their cellular composition with regard to functionally important immune and stromal subsets. These differences are likely to have immunologic, pathologic, and physiologic significance.
https://ift.tt/2Cc388u
Differential Cellular Composition of Human Palatine and Pharyngeal Tonsils
Publication date: Available online 1 September 2018
Source: Archives of Oral Biology
Author(s): Luke Stanisce, Etty Sims, Cheryl Hou, Yekaterina Koshkareva, John P. Gaughan, Igor Kuzin, Andrea Bottaro
Abstract
Objective
The goal of this study was to gain a better understanding of the potential functional specialization of palatine and pharyngeal tonsils, by comparing their cellular composition in paired specimens from a large cohort of adenotonsillectomy patients.
Design
Resident B cell, T cell, dendritic cell, and stromal cell subsets were characterized using multicolor flow cytometry in palatine and pharyngeal tonsil specimens from 27 patients, age 2-34 years.
Results
Paired comparisons showed highly significant intra-individual differences in resident cell subsets of palatine and pharyngeal tonsils. Palatine tonsils harbored higher fractions of germinal center B cells/plasmablasts and IgD- CD27- double-negative B cells, and conversely lower fractions of IgD + CD38- resting naïve B cells compared to pharyngeal tonsils. Palatine tonsils also showed lower fractions of plasmacytoid dendritic cells, and higher percentages of two subsets of stromal cells - fibroblastic reticular cells and lymphatic endothelial cells - compared to pharyngeal tonsils from the same individual.
Conclusions
Despite their physical proximity and histological similarities, palatine and pharyngeal tonsils display marked intra-individual differences in their cellular composition with regard to functionally important immune and stromal subsets. These differences are likely to have immunologic, pathologic, and physiologic significance.
https://ift.tt/2Cc388u
Diagnostic heuristics in dermatology, Part 2: Metacognition and other fixes
British Journal of Dermatology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2LOXusj
Topical resiquimod dosing regimens in patients with multiple actinic keratosis: a multi‐centre, partly placebo‐controlled, double‐blind, clinical trial
British Journal of Dermatology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2wy5hWI
Assessing the Severity of Pyoderma Gangrenosum – A Need for Validated Measurement Tools
British Journal of Dermatology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2NDtpxy
Lack of Confidence Interval Reporting in Dermatology: A Call to Action
British Journal of Dermatology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2wC31xw
Protection of glucotoxicity by a tripeptide derivative of α‐melanocyte‐stimulating hormone in human epidermal keratinocytes
British Journal of Dermatology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2LNYBZt
To what extent do disease severity and illness perceptions explain depression, anxiety and quality of life in Hidradenitis Suppurativa
British Journal of Dermatology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2wy72mQ
Autoantibodies undetectable by chemiluminescent enzyme immunoassay require extended antigen‐antibody reaction time for detection
British Journal of Dermatology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2LRhLO9
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