OtoRhinoLaryngology New Articles & Online Journals

28mOtoRhinoLaryngology - Alexandros G. SfakianakisCritical Care Medicine The Effect of Dexamethasone on Symptoms of Posttraumatic Stress Disorder and Depression After Cardiac Surgery and Intensive Care Admission: Longitudinal Follow-Up of a Randomized Controlled Trial.Objective: Cardiac surgery and postoperative admission to the ICU may lead to posttraumatic stress disorder...29mOtoRhinoLaryngology - Alexandros G. SfakianakisCurrent Opinion in Anesthesiology The role of ultrasound guidance for vascular access.Purpose of review: Ultrasound-guided cannulation of the internal jugular vein has become a standard practice over recent years. Despite known benefits, ultrasound is less frequently used for other vascular applications probably because these are technically...30mOtoRhinoLaryngology - Alexandros G. SfakianakisInternational Journal of Rehabilitation Research Confirmatory factor analysis of the Arabic version of the Lower Extremity Functional Scale.The aim of this study was to examine the factorial structure of the Arabic version of the Lower Extremity Functional Scale (LEFS-Ar) using a confirmatory factor analysis. The study was designed as a cross-sectional...31mOtoRhinoLaryngology - Alexandros G. SfakianakisJournal of Trauma and Acute Care Surgery Contributions of the surgeon Nikolai Korotkov (1874-1920) to the management of extremity vascular injury.The Russian military surgeon Nikolai Korotkov is known worldwide, mainly among internists and cardiovascular specialists, as the discoverer of the auscultatory method of measuring arterial blood pressure...31mOtoRhinoLaryngology - Alexandros G. SfakianakisMedicine & Science in Sports & Exercise Effects of Oral Contraceptive Use on Anterior Cruciate Ligament Injury Epidemiology.Introduction/Purpose: Anterior cruciate ligament injuries often incur major consequences for athletes. Elevated estrogen levels are likely increase the risk for injury. This risk may be partially or fully mitigated by...34mOtoRhinoLaryngology - Alexandros G. SfakianakisJournal of Allergy and Clinical Immunology ReplyPublication date: Available online 6 November 2015Source:Journal of Allergy and Clinical ImmunologyAuthor(s): Antonino Romano, Francesco Gaeta, Rocco Luigi Valluzzi, Michela Maggioletti, Alessandra Zaffiro, Cristiano Caruso, Donato QuaratinoSubgroups in cephalosporin allergy, making a patient-tailored...35mOtoRhinoLaryngology - Alexandros G. SfakianakisBritish Journal of Oral and Maxillofacial Surgery Can a one-day practical lesson in surgical skills encourage medical students to consider a surgical career?Publication date: Available online 6 November 2015Source:British Journal of Oral and Maxillofacial SurgeryAuthor(s): Florian Bauer, Niklas Rommel, Steffen Koerdt, Andreas Fichter, Klaus-Dietrich...37mOtoRhinoLaryngology - Alexandros G. Sfakianakis:Medical Journal Armed Forces India Acceptance of family planning methods by induced abortion seekers: An observational study over five yearsPublication date: Available online 17 October 2015Source:Medical Journal Armed Forces IndiaAuthor(s): S.K. KathpaliaBackground Prior to legalization of abortion, induced abortions were performed in...39mOtoRhinoLaryngology - Alexandros G. SfakianakisClinical Nuclear Medicine Value of 18F-FDG PET/CT for Predicting the World Health Organization Malignant Grade of Thymic Epithelial Tumors: Focused in Volume-Dependent Parameters.Purpose: We investigated whether preoperative parameters of 18F-FDG PET/CT were correlated with the World Health Organization (WHO) classification and/or...40mOtoRhinoLaryngology - Alexandros G. SfakianakisOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Editorial BoardPublication date: December 2015Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 120, Issue 6ContentsPublication date: December 2015Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 120, Issue 6Society PagePublication date: December...41mOtoRhinoLaryngology - Alexandros G. SfakianakisPlastic and Reconstructive Surgery – Global Open Treatment of Skin Depression with Combined Upward Suture Traction and Percutaneous SubcisionBackground: Scar retraction and soft-tissue depression may compromise aesthetics and cause social embarrassment. The purpose of this study was to evaluate the results of treating soft-tissue depressions or retractions...43mOtoRhinoLaryngology - Alexandros G. SfakianakisPharmacogenetics and Genomics CYP2C9 variants as a risk modifier of NSAID-related gastrointestinal bleeding: a case-control study.Objective: The aim of this study was to assess whether the CYP2C9*2 and/or *3 variants might modify the risk for NSAID-related upper gastrointestinal bleeding (UGIB) in NSAID users. Patients and methods:...44mOtoRhinoLaryngology - Alexandros G. SfakianakisAmerican Journal of Physical Medicine & Rehabilitation Radial Extracorporeal Shock Wave Therapy Is Not More Effective Than Placebo in the Management of Lateral Epicondylitis: A Double-Blind, Randomized, Placebo-Controlled Trial.Objectives: The aim of this study was to investigate the effects of radial extracorporeal shock wave therapy (rESWT) on pain, function,...46mOtoRhinoLaryngology - Alexandros G. Sfakianakis:Otolaryngologic Clinics of North America Hearing Loss in ChildrenPublication date: December 2015Source:Otolaryngologic Clinics of North America, Volume 48, Issue 6Author(s): Bradley W. Kesser, Margaret A. KennaCopyrightPublication date: December 2015Source:Otolaryngologic Clinics of North America, Volume 48, Issue 6CME Accreditation PagePublication...1hHuman DiseasesCase Reports in General Practice  48-year-old patient who had suffered from polyarthritis from his age 40. Initial laboratory tests showed low inflammatory...Case Discussions ( 0 ) | Rates: 0  66-year-old female presenting with AFF within three years of starting ibandronate and after receiving a total of 27 doses...Case Discussions...1hEvolution of a geneHuman Genetics Pathway-based variant enrichment analysis on the example of dilated cardiomyopathyAbstractGenome-wide association (GWA) studies have significantly contributed to the understanding of human genetic variation and its impact on clinical traits. Frequently only a limited number of highly significant associations...1hΕνδοκρινολογίαThe Journal of Clinical Endocrinology & Metabolism  Home PageCurrent IssuePast IssuesAbout This IssueCover and Front MatterEditorial BoardTable of ContentsBack MatterSpecial FeaturesA Girl With Beckwith-Wiedemann Syndrome and Pseudohypoparathyroidism Type 1B Due to Multiple Imprinting DefectsBoudewijn Bakker, Laura J. H. Sonneveld, M. Claire Woltering,...1hCancerHepatosplenic Alpha/Beta T-cell Lymphoma Presenting with Coombs'-negative Hemolytic Anemia An Unusual Case of Abstract:Hepatosplenic T-cell lymphoma (HSTCL) is a rare and aggressive extranodal T-cell lymphoma that comprises less than 5% of peripheral T-cell lymphomas. The majority of cases harbor the γδ T-cell receptor but recently a few cases have been shown to express the αβ T-cell receptor....5hOtoRhinoLaryngology - Alexandros G. SfakianakisThe reflux of pancreatic–duodenal fluids is implicated in the pathophysiology of proton-pump inhibitor-resistant gastroesophageal reflux disease (GERD) Protease-Activated Receptor-2 Up-Regulates Transient Receptor Potential Vanilloid 4 Function in Mouse Esophageal Keratinocyte: AbstractBackgroundThe reflux of pancreatic–duodenal fluids is implicated in the pathophysiology of proton-pump inhibitor-resistant gastroesophageal reflux disease (GERD). Protease-activated...5hHead and NeckMusic identification skills of children with specific language impairment. Int J Lang Commun Disord. 2015 Nov 6;Authors: Mari G, Scorpecci A, Reali L, D'Alatri LAbstract BACKGROUND: To date very few studies have investigated the musical skills of children with specific language impairment (SLI). There is growing evidence that SLI affects areas other than language, and...5hHead and NeckEffect of explicit dimensional instruction on speech category learning. Atten Percept Psychophys. 2015 Nov 5;Authors: Chandrasekaran B, Yi HG, Smayda KE, Maddox WTAbstract Learning nonnative speech categories is often considered a challenging task in adulthood. This difficulty is driven by cross-language differences in weighting critical auditory dimensions that...5hHead and NeckAssessment of Nonverbal and Verbal Apraxia in Patients with Parkinson's Disease. Parkinsons Dis. 2015;2015:840327Authors: Presotto M, Olchik MR, Shumacher Shuh AF, Rieder CRAbstract Objective. To assess the presence of nonverbal and verbal apraxia in patients with Parkinson's disease (PD) and analyze the correlation between these conditions and patient age, education, duration...5hHead and NeckAssociation between Rare Variants in AP4E1, a Component of Intracellular Trafficking, and Persistent Stuttering. Am J Hum Genet. 2015 Nov 5;97(5):715-725Authors: Raza MH, Mattera R, Morell R, Sainz E, Rahn R, Gutierrez J, Paris E, Root J, Solomon B, Brewer C, Basra MA, Khan S, Riazuddin S, Braun A, Bonifacino JS, Drayna DAbstract Stuttering is a common, highly heritable neurodevelopmental disorder characterized...5hHead and NeckReadout-segmented Echo-planar Imaging in the Evaluation of Sinonasal Lesions: A Comprehensive Comparison of Image Quality in Single-shot Echo-planar Imaging. Magn Reson Imaging. 2015 Nov 2;Authors: Zhao M, Liu Z, Sha Y, Wang S, Ye X, Pan Y, Wang SAbstract PURPOSE: To investigate the role of readout-segmented echo-planar imaging using parallel imaging and a two-dimensional (2D) navigator (RESOLVE) in the evaluation of sinonasal lesions and to qualitatively...5hHead and NeckInflammatory Myofibroblastic Tumor of the Left Sphenoid and Cavernous Sinus Successfully Treated with Partial Resection and High Dose Radiotherapy: Case Report and Review of the Literature. Cureus. 2015;7(9):e328Authors: Gabel BC, Goolsby M, Hansen L, U HSAbstractInflammatory myofibroblastic tumors, also known as plasma cell granulomas or inflammatory pseudotumors, are uncommon lesions that are known to arise in many areas of the body. They are uncommonly found in the skull base region...5hOtoRhinoLaryngology - Alexandros G. SfakianakisComparison of Autoimmune Thyroid Disease in Patients With Progressive and Stable Vitiligo Comparison of Autoimmune Thyroid Disease in Patients With Progressive and Stable Vitiligo: Background and Objective:Activity of vitiligo has not been considered as a patient selection criteria in previous studies; we decided to compare the presence of elevated thyroid auto-antibodies in patients with...5hOtoRhinoLaryngology - Alexandros G. SfakianakisIndirect Immunofluorescence for the Detection of Autoimmune Urticaria Indirect Immunofluorescence for the Detection of Autoimmune Urticaria: Background:An autoimmune basis is believed to be responsible for about half of chronic spontaneous urticaria (CSU) cases. The autologous serum skin test is used as a possible indicator, but there is currently no test that directly...5hOtoRhinoLaryngology - Alexandros G. SfakianakisTrends in Non-Melanoma Skin Cancer (Basal Cell Carcinoma and Squamous Cell Carcinoma) in Canada: A Descriptive Analysis of Available Data Trends in Non-Melanoma Skin Cancer (Basal Cell Carcinoma and Squamous Cell Carcinoma) in Canada: A Descriptive Analysis of Available Data: Background:Despite its increased incidence and status as the most prevalent cancer in Canada, there is a paucity of epidemiological data on non-melanoma skin cancer...5hOtoRhinoLaryngology - Alexandros G. SfakianakisLupus Miliaris Disseminatus Faciei With Isolated Axillary Involvement Lupus Miliaris Disseminatus Faciei With Isolated Axillary Involvement: Background:Lupus miliaris disseminatus faciei (LMDF) is a chronic, granulomatous inflammatory disorder, commonly localized to the face.Objective:To present an unusual manifestation of LMDF and review the literature.Methods:We document...5hOtoRhinoLaryngology - Alexandros G. SfakianakisContact Dermatitis to Personal Sporting Equipment in Youth Contact Dermatitis to Personal Sporting Equipment in Youth: Background:Contact dermatitis to personal sporting equipment in youth is poorly studied.Objective:To review the results of patch testing 6 youth to their sporting equipment in a dermatology general private practice from 2006 to 2011.Methods:A...5hOtoRhinoLaryngology - Alexandros G. SfakianakisHobnail Hemangioma (Superficial Hemosiderotic Lymphovascular Malformation) in Children: A Series of 6 Pediatric Cases and Review of the Literature Hobnail Hemangioma (Superficial Hemosiderotic Lymphovascular Malformation) in Children: A Series of 6 Pediatric Cases and Review of the Literature: Background:Hobnail hemangioma is a small benign vascular malformation of the superficial and mid-dermis with variable clinical presentation.Objectives:To...5hHead and Neck[The role of the cerebellum in auditory process and tinnitus]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Du Y, Liu J, Kang WAbstract Cerebellum connects with each part of the auditory pathway directly or indirectly, forming the anatomical basis for a cerebellar role in auditory process. Functional imaging studies and clinical observations...5hHead and NeckEffects of sound amplification in self-perception of tinnitus and hearing loss in the elderly. Braz J Otorhinolaryngol. 2015Authors: Araujo TM, Iório MCAbstract OBJECTIVE: To determine the effect of the use of hearing aids in self-perception of tinnitus and hearing loss in the elderly. METHODS: A total of 24 elderly patients between 60 and 70 years of age with moderate-grade sensorineural...5hHead and NeckEffectiveness of sound therapy in patients with tinnitus resistant to previous treatments: importance of adjustments. Braz J Otorhinolaryngol. 2015 ;Authors: Barros Suzuki FA, Suzuki FA, Yonamine FK, Onishi ET, Penido NOAbstract INTRODUCTION: The difficulty in choosing the appropriate therapy for chronic tinnitus relates to the variable impact on the quality of life of affected patients and, thus, requires individualization...6hHead and NeckAnalysis of acutely exacerbated chronic tinnitus by the Tinnitus Handicap Inventory. J Laryngol Otol. 2015 Nov 6;:1-4Authors: Zeng X, Li P, Li Z, Cen J, Li Y, Zhang GAbstract OBJECTIVE: To examine factors potentially contributing to acutely exacerbated chronic tinnitus initiation using the Tinnitus Handicap Inventory. METHODS: Sixty acutely exacerbated chronic tinnitus...6hHead and NeckMenière's disease. BMJ Clin Evid. 2015;2015Authors: Wright TAbstract INTRODUCTION: Menière's disease causes feelings of fullness or pressure in the ear, hearing loss, tinnitus, and recurrent bouts of vertigo, and mainly affects people aged 30-60 years. Menière's disease is at first progressive but fluctuating,...6hHead and NeckSilencing SOX2 Expression by RNA Interference Inhibits Proliferation, Invasion and Metastasis, and Induces Apoptosis through MAP4K4/JNK Signaling Pathway in Human Laryngeal Cancer TU212 Cells. Authors: Yang N, Wang Y, Hui L, Li X, Jiang XAbstractSRY (sex determining region Y)-box 2 (SOX2) plays an important role in tumor cell metastasis and apoptosis. Laryngeal squamous cell carcinoma (LSCC), responsible for 1.5% of all cancers, is one of the most common head and neck malignancies. Accumulating...6hOtoRhinoLaryngology - Alexandros G. SfakianakisThe Skin Microbiome in Atopic Dermatitis and Its Relationship to Emollients The Skin Microbiome in Atopic Dermatitis and Its Relationship to Emollients: Background:Human-associated bacterial communities on the skin, skin microbiome, likely play a central role in development of immunity and protection from pathogens. In atopic patients, the skin bacterial diversity is smaller...6hOtoRhinoLaryngology - Alexandros G. SfakianakisThe Use of the PlasmaBlade and Acellular Dermal Matrix in Rhinophyma Surgery: A Case Report The Use of the PlasmaBlade and Acellular Dermal Matrix in Rhinophyma Surgery: A Case Report: Background:Rhinophyma is a rare, disfiguring disease characterized by a slow progressive overgrowth of the soft tissue of the nose associated with end-stage severe acne rosacea.Objective:We present a case of...6hOtoRhinoLaryngology - Alexandros G. SfakianakisRadiotherapy in Gorlin Syndrome: Can It Be Safe and Effective in Adult Patients? Radiotherapy in Gorlin Syndrome: Can It Be Safe and Effective in Adult Patients?: Gorlin syndrome, also known as nevoid basal cell carcinoma syndrome, is a rare autosomal dominant disorder with multiple manifestations including early onset of cutaneous basal cell carcinomas (BCCs). Radiotherapy has traditionally...6hOtoRhinoLaryngology - Alexandros G. SfakianakisPyodermatitis-pyostomatitis vegetans (PDPSV) is a rare inflammatory disorder of the skin and oral mucosa Pyoblepharitis Vegetans in Association With Pyodermatitis-Pyostomatitis Vegetans: Expanding the Spectrum of a Rare, Multisystem Disorder: Background:Pyodermatitis-pyostomatitis vegetans (PDPSV) is a rare inflammatory disorder of the skin and oral mucosa that is commonly associated with inflammatory bowel...6hOtoRhinoLaryngology - Alexandros G. SfakianakisThe Management of Flap/Defect Discrepancies in Rotation Flaps Crescentic Back Cut: A Novel Technique for the Management of Flap/Defect Discrepancies in Rotation Flaps: Background:Facial reconstruction requires the use of various techniques to repair cutaneous defects. Sliding flaps, such as advancement and rotation flaps, typically result in tension alterations...6hOtoRhinoLaryngology - Alexandros G. SfakianakisAutoimmune Bullous Dermatoses Loss of Work Productivity and Quality of Life in Patients With Autoimmune Bullous Dermatoses: Background:Little is known about quality of life and work productivity in autoimmune bullous dermatoses (AIBDs).Objective:To determine the impact of AIBDs on quality of life and work productivity.Methods:An...6hOtoRhinoLaryngology - Alexandros G. SfakianakisEfficacy of Topical Calcineurin Inhibitors in Oral Lichen Planus Efficacy of Topical Calcineurin Inhibitors in Oral Lichen Planus: Background:Oral lichen planus (OLP) is associated with severe pain and significant impairment for patients.Objective:To evaluate the safety and efficacy of topical calcineurin inhibitors (TCI) in the treatment of OLP.Methods:Medline and...6hOtoRhinoLaryngology - Alexandros G. SfakianakisA Retrospective Review of Reconstructive Options and Outcomes of 202 Cases Large Facial Mohs Micrographic Surgical Defects, Based on the Aesthetic Unit Involved A Retrospective Review of Reconstructive Options and Outcomes of 202 Cases Large Facial Mohs Micrographic Surgical Defects, Based on the Aesthetic Unit Involved: Background:For optimal treatment of facial defects following Mohs micrographic surgery (MMS), the aesthetic unit principles should be applied....6hOtoRhinoLaryngology - Alexandros G. SfakianakisAcute Generalized Exanthematous Pustulosis Induced by Amoxicillin/Clavulanic Acid: Report of a Case Presenting With Generalized Lymphadenopathy Acute Generalized Exanthematous Pustulosis Induced by Amoxicillin/Clavulanic Acid: Report of a Case Presenting With Generalized Lymphadenopathy: Drug-induced acute generalized exanthematous pustulosis is a rare pustular skin reaction, most commonly triggered by antibiotics. Although its diagnosis is...6hΑισθητική ΔερματολογίαJournal of Cutaneous Medicine and Surgery Pyoblepharitis Vegetans in Association With Pyodermatitis-Pyostomatitis Vegetans: Expanding the Spectrum of a Rare, Multisystem DisorderBackground:Pyodermatitis-pyostomatitis vegetans (PDPSV) is a rare inflammatory disorder of the skin and oral mucosa that is commonly associated with inflammatory bowel...6hHead and NeckHypertrichosis Lanuginosa Acquisita Associated With Endometrial Adenocarcinoma. Authors: Dalcin D, Manser C, Mahler RAbstract BACKGROUND: Skin changes often signal systemic disease. Hypertrichosis lanuginosa acquisita (HLA) is a well-recognized symptom of internal malignancy defined as the adult onset of colourless, fine, lanugo-type hairs. To our knowledge, only 5 cases...6hHead and NeckControversies in small cell carcinoma of the head and neck: Prophylactic cranial irradiation (PCI) after primary complete initial remission. Authors: De Felice F, Lei M, Guerrero Urbano TAbstract Small cell carcinoma of head and neck region (SmCCHN) represents a rare entity and its management remains a significant clinical challenge. Complete initial response to primary therapy poses a difficult and controversial scenario for radiation...6hHead and Neck[Isolated central nervous system relapse in type II enteropathy-associated T cell lymphoma]. Authors: Nishida H, Endo K, Hatano M, Tatekawa N, Mashima E, Hashida R, Hori M, Obara KAbstract A 75-year-old male presented with progressive lower abdominal discomfort. CT scan demonstrated hypertrophy of the intestinal wall, small bowel dilatation, and masses in the descending colon. Biopsy...6hHead and NeckIncidental Finding of Metastatic Cutaneous Malignant Melanoma at Uterine Leiomyoma, A Thai University Hospital Experience: A Case Report. J Med Assoc Thai. 2015Authors: Chanthasenanont A, Nantakomon T, Kintarak J, Vithisuvanakul N, Pongrojpaw D, Suwannarurk KAbstract BACKGROUND: Metastatic malignant melanomas to the uterus are extremely rare; to our knowledge, no more than 13 cases have been reported to date. CASE REPORT:...6hHead and NeckInflammatory dentigerous cyst of mandibular first premolar associated with endodontically treated primary first molar: a rare case report. Eur J Paediatr Dent. 2015Authors: Yao L, Xu X, Ren M, Liu D, Ni Z, Lin FAbstract AIM: Inflammatory dentigerous cysts usually occur in the mixed dentition. It has been reported that inflammatory lesions from the root area of a deciduous tooth bring about the development of dentigerous cysts around...6hHead and NeckAn unusual case of metastatic male breast cancer to the nasopharynx-review of literature. An unusual case of metastatic male breast cancer to the nasopharynx-review of literature.: An unusual case of metastatic male breast cancer to the nasopharynx-review of literature.Ann Palliat Med. 2015 Oct;4(4):233-8Authors: Agrawal S, Jayant K, Agarwal RK, Dayama KG, Arora SAbstract Metastatic...6hHead and NeckMalignancies in pregnancy. Malignancies in pregnancy.: Malignancies in pregnancy.Best Pract Res Clin Obstet Gynaecol. 2015 Oct 19;Authors: Albright CM, Wenstrom KDAbstract Malignancy complicating pregnancy is fortunately rare, affecting one in 1000 to one in 1500 pregnancies. Optimal treatment involves balancing the benefit...6hHead and NeckSolitary fibrous tumors of the pleura Outcome of surgery in patients with solitary fibrous tumors of the pleura.: Outcome of surgery in patients with solitary fibrous tumors of the pleura.Asian Cardiovasc Thorac Ann. 2015 Nov 5;Authors: Fattahi Masuom SH, Bagheri R, Sadrizadeh A, Nouri Dalouee M, Taherian A, Rajaie ZAbstract BACKGROUND:...6hHead and NeckAnesthetic management for bronchoscopy and debulking of obstructing intratracheal tumor. Anesthetic management for bronchoscopy and debulking of obstructing intratracheal tumor.: Anesthetic management for bronchoscopy and debulking of obstructing intratracheal tumor.Saudi J Anaesth. 2015 Oct-Dec;9(4):484-8Authors: Uma B, Kochhar A, Verma UC, Rautela RSAbstract Primary tracheal tumors...6hHead and NeckConstitutional Mismatch Repair Deficiency Constitutional Mismatch Repair Deficiency in Israel: High Proportion of Founder Mutations in MMR Genes and Consanguinity.: Constitutional Mismatch Repair Deficiency in Israel: High Proportion of Founder Mutations in MMR Genes and Consanguinity.Pediatr Blood Cancer. 2015 Nov 6;Authors: Baris HN, Barnes-Kedar...6hHead and NeckmiR-150 inhibits terminal erythroid proliferation and differentiation. miR-150 inhibits terminal erythroid proliferation and differentiation.: miR-150 inhibits terminal erythroid proliferation and differentiation.Oncotarget. 2015 Nov 3;Authors: Sun Z, Wang Y, Han X, Zhao X, Peng Y, Li Y, Peng M, Song J, Wu K, Sun S, Zhou W, Qi B, Zhou C, Chen H, An X, Liu JAbstract ...6hHead and NeckLeptomeningeal metastasis Leptomeningeal metastasis in breast cancer - a systematic review.: Leptomeningeal metastasis in breast cancer - a systematic review.Oncotarget. 2015 Nov 2;Authors: Scott BJ, Oberheim-Bush NA, Kesari SAbstract BACKGROUND: There is limited data on the impact of specific patient characteristics,...6hHead and NeckRisk prediction for sporadic Alzheimer's disease using genetic risk score Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population.: Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population.Oncotarget. 2015 Nov 2;Authors: Xiao Q, Liu ZJ, Tao S, Sun YM, Jiang D, Li HL, Chen H, Liu...6hHead and NeckAerobic glycolysis and cancer cell proliferation. Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation.: Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation.Oncotarget....6hHead and NeckMutant HRAS as novel target for MEK and mTOR inhibitors. Mutant HRAS as novel target for MEK and mTOR inhibitors.: Mutant HRAS as novel target for MEK and mTOR inhibitors.Oncotarget. 2015 Nov 3;Authors: Kiessling MK, Curioni-Fontecedro A, Samaras P, Atrott K, Cosin-Roger J, Lang S, Scharl M, Rogler GAbstract HRAS is a frequently mutated oncogene in...6hHead and NeckTransforming growth factor-β1 polymorphisms and graft-versus-host disease risk: a meta-analysis. Transforming growth factor-β1 polymorphisms and graft-versus-host disease risk: a meta-analysis.: Transforming growth factor-β1 polymorphisms and graft-versus-host disease risk: a meta-analysis.Oncotarget. 2015 Nov 3;Authors: Zhang L, Mao L, Xu JAbstract Some studies have demonstrated that transforming...6hHead and NeckGenetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia. Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia.: Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia.Oncotarget. 2015 Oct 30;Authors: Safavi S, Olsson L, Biloglav A, Veerla S, Blendberg M, Tayebwa J, Behrendtz M, Castor A, Hansson...6hHead and NeckHybrid lateral mass screw sublaminar wire construct: A salvage technique for posterior cervical fixation in pediatric spine surgery. Hybrid lateral mass screw sublaminar wire construct: A salvage technique for posterior cervical fixation in pediatric spine surgery.: Hybrid lateral mass screw sublaminar wire construct: A salvage technique for posterior cervical fixation in pediatric spine surgery.J Clin Neurosci. 2015 Nov 2;Authors:...6hHead and NeckAsymptomatic progressive multifocal leukoencephalopathy during natalizumab therapy with treatment. Asymptomatic progressive multifocal leukoencephalopathy during natalizumab therapy with treatment.: Asymptomatic progressive multifocal leukoencephalopathy during natalizumab therapy with treatment.J Clin Neurosci. 2015 Nov 2;Authors: Fabis-Pedrini MJ, Xu W, Burton J, Carroll WM, Kermode AGAbstract...6hHead and NeckSpontaneous acute subdural hematoma: A rare presentation of a dural intracranial fistula. Spontaneous acute subdural hematoma: A rare presentation of a dural intracranial fistula.: Spontaneous acute subdural hematoma: A rare presentation of a dural intracranial fistula.J Clin Neurosci. 2015 Nov 2;Authors: de Aguiar GB, Veiga JC, de Almeida Silva JM, Conti MLAbstractDural arteriovenous fistulas...6hOtoRhinoLaryngology - Alexandros G. SfakianakisMutant GDF15 presents a poor prognostic outcome for patients with oral squamous cell carcinoma. Mutant GDF15 presents a poor prognostic outcome for patients with oral squamous cell carcinoma.: Mutant GDF15 presents a poor prognostic outcome for patients with oral squamous cell carcinoma.Oncotarget. 2015 Oct 19;Authors: Ma J, Tang X, Sun WW, Liu Y, Tan YR, Ma HL, Zhu DW, Wang M, Wang LZ, Li J,...6hOtoRhinoLaryngology - Alexandros G. Sfakianakis5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53. 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53.: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53.Oncotarget. 2015 Oct 24;Authors: Akpinar B, Bracht EV, Reijnders D, Safarikova B, Jelinkova I, Grandien...6hOtoRhinoLaryngology - Alexandros G. SfakianakisDeterminants of long-term quality of life in patients with differentiated thyroid carcinoma - a population-based cohort study in Sweden. Determinants of long-term quality of life in patients with differentiated thyroid carcinoma - a population-based cohort study in Sweden.: Determinants of long-term quality of life in patients with differentiated thyroid carcinoma - a population-based cohort study in Sweden.Acta Oncol. 2015 Nov 5;:1-5Authors:...6hOtoRhinoLaryngology - Alexandros G. SfakianakisLong-Term Surveillance of Treated Hyperparathyroidism for Multiple Endocrine Neoplasia Type 1: Recurrence or Hypoparathyroidism? Long-Term Surveillance of Treated Hyperparathyroidism for Multiple Endocrine Neoplasia Type 1: Recurrence or Hypoparathyroidism?: Long-Term Surveillance of Treated Hyperparathyroidism for Multiple Endocrine Neoplasia Type 1: Recurrence or Hypoparathyroidism?World J Surg. 2015 Nov 5;Authors: Fyrsten...6hOtoRhinoLaryngology - Alexandros G. SfakianakisUse of 3D Prototypes for Complex Surgical Oncologic Cases. Use of 3D Prototypes for Complex Surgical Oncologic Cases.: Use of 3D Prototypes for Complex Surgical Oncologic Cases.World J Surg. 2015 Nov 5;Authors: Krauel L, Fenollosa F, Riaza L, Pérez M, Tarrado X, Morales A, Gomà J, Mora JAbstract INTRODUCTION: Physical 3D models known by the industry...6hOtoRhinoLaryngology - Alexandros G. SfakianakisStent and Pressure Activated Nanoparticles to Bust Clots New Stroke Technology: Stent and Pressure Activated Nanoparticles to Bust Clots: Some ischemic strokes are now successfully treated using intravascular clot retrieval devices, but in many instances this option is not advised. Moreover, the retriever can dislodge bits of the clot that end up embolizing...6hOtoRhinoLaryngology - Alexandros G. SfakianakisThermal Imaging to Study Stress Non-invasively Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds: There is a need for a non-invasive assessment of stress. This paper describes a simple protocol using thermal imaging to detect a significant response in eye-region temperature in wild blue tits to a mild acute stressor.6hHead and NeckStudy of factors determining caregiver burden among primary caregivers of patients with intracranial tumors. Surg Neurol Int. 2015;6:160Authors: Dhandapani M, Gupta S, Dhandapani S, Kaur P, Samra K, Sharma K, Dolma K, Mohanty M, Singla N, Gupta SKAbstract BACKGROUND: Caregivers of patients with intracranial tumors handle physical, cognitive, and behavioral impairments of patients. The purpose of this...6hHead and NeckA case of a brain stem abscess with a favorable outcome. Surg Neurol Int. 2015;6:161Authors: Bulthuis VJ, Gubler FS, Teernstra OP, Temel YAbstract BACKGROUND: A brain stem abscess is a rare and severe medical condition. Here, we present a rare case of a brain stem abscess in a young pregnant woman, requiring acute stereotactic intervention. ...6hHead and NeckVitamin D deficiency and fatigue: an unusual presentation. Springerplus. 2015;4:584Authors: Johnson K, Sattari MAbstract Fatigue is a vague but common complaint that is poorly characterized by physicians as well as patients. While fatigue may result from a number of different etiologies, at the present time, a comprehensive approach to each patient with...6hHead and Neck[The study of siRNA interference after laryngeal cancer Hep-2 cells to cisplatin sensitivity of β-catenin gene expression]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Yu F, Huang X, Ai M, Lin YAbstract OBJECTIVE: To investigate the changes of laryngeal cancer Hep-2 cells to cisplatin chemosensitivity after the interference of siRNA of β-catenin gene expression. METHOD: Using a small interference...6hHead and Neck[The expression of Nrf2 and Keap1 in laryngeal carcinoma and its clinical indication]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Yuan Y, Shan C, Xu O, Wang J, Zhang HAbstract OBJECTIVE: To investigate the role of Keap1-Nrf2-ARE pathway in laryngeal carcinoma occurrence and development. METHOD: Thirty-five laryngeal carcinoma samples and para-carcinoma...6hHead and Neck[The expression of PKM2 and HIF-1α in laryngeal squamous cell carcinoma and its clinical indication]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Liu X, Shan C, Xu O, Wang J, Zhang HAbstract OBJECTIVE: The purpose of this study was to investigate the expression of PKM2 and HIF-1α in laryngeal squamous cell carcinoma and to analyze their correlation in laryngeal squamous cell...6hHead and Neck[The expression of Endophilin II and VEGF-C in human laryngeal cancer and connection with clinical treatment]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Yin ZP, Yang CAbstract OBJECTIVE: To study the expression of Endophilin II and VEGF-C in human Laryngeal cancer and its relationship with the clinical treatment effect. METHOD: The expression and distribution of Endophilin II...6hHead and Neck[The expression of Endophilin II and VEGF-C in human laryngeal cancer and connection with clinical treatment]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Yin ZP, Yang CAbstract OBJECTIVE: To study the expression of Endophilin II and VEGF-C in human Laryngeal cancer and its relationship with the clinical treatment effect. METHOD: The expression and distribution of Endophilin II...6hHead and Neck[Relationship of local recurrence with the expression of Survivin and MMP-2 in laryngeal carcinoma and its surgical margins]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Zhou B, Hou X, Shi S, Yang FAbstract OBJECTIVE: To explore the relationship of the local recurrence with the expression of protein Survivin and MMP-2 in the primary lesions and the surgical margins of laryngeal carcinoma. METHOD:...6hHead and Neck[The sequencing analyze of 915 newborn with GJB2 heterozygous mutation in Beijing]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Cui Qingjia, Huang Lihui, Ruan Yu, Du Yanshun, Zhao Liping, Yang Jun, Zhang WeiAbstract OBJECTIVE: To determine GJB2 allelic mutant and estimate probability of hereditary hearing loss in newborn with GJB2 heterozygous mutation in Beijing....6hHead and Neck[The development of vocabulary capability at 2-year follow-up in the prelingual deaf children with cochlear implants]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Fu Y, Chen Y, Hong M, Chen A, Wang Q, Xi X, Wong LAbstract OBJECTIVE: To investigate the development of early vocabulary capability in the prelingual deaf children after cochlear implantation (CI) , and to study the feasibility of current...6hHead and Neck[The research of rehabilitation effect of cochlear implantation for deaf children with gene mutation]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Kong Y, Liang S, Ren C, Liu X, Liu SAbstract OBJECTIVE: To assess the evaluation on auditory rehabilitation effect for 42 deaf children with GJB2 gene mutation after cochlear implantation to provide a reference for the cochlear implant...6hHead and Neck[Cervical vestibular evoked myogenic potential elicited by different types air conducted sounds among normal young Chinese people]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Yang Y, Zhang Q, Zhang R, Chen Y, Wu C, Kou X, Kong D, Jing X, Xu MAbstract OBJECTIVE: To observe waveform difference among cervical vestibular evoked myogenic potentials (cVEMP) elicited with different types of air conducted sound...6hHead and Neck[Activation of mTOR signaling pathway in cancer stem cells of nasopharyngeal carcinoma and inhibitive effect of rapamycin against the cancer stem cells]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Zhang Y, Lin R, Zhang Z, Chen J, Yang C, Zhou L, Zhang YAbstract OBJECTIVE: To study the mTOR expression of cancer stem cells(CSCs) in nasopharyngeal carcinoma and preliminarily explore the mechanism of inhibiting its proliferation...6hHead and Neck[Expressions of Maspin and Ki67 in extranodal nasal type NK/T-cell lymphoma and the significance]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Hong F, Sun J, Li C, Wang X, Chen J, Gu PAbstract OBJECTIVE: To analyze the expression of Maspin and Ki67 in EN-NK/TCL and the significance. METHOD: The expressions of Maspin and Ki67 were detected by immunohistochemistry in...6hHead and Neck[A clinical study of 27 cases of cervical metastatic carcinoma of unknown primary site]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Li W, Xin D, Zhang QAbstract OBJECTIVE: To analyze the clinical feature of cervical metastatic carcinoma of unknown primary site (CCUP) for guiding clinical diagnosis and treatment. METHOD: Twenty-seven cases of CCUP during May...6hHead and Neck[The surgical options of cervical tuberculous lymphadenitis]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Li Z, Li J, Liao X, Li X, Fang HAbstract OBJECTIVE: To analyze the clinical features & variation features of cervical tuberculous lymphadenitis and to discuss its effective surgical treatment. METHOD: Retrospective analysis...6hHead and Neck[The effect of TFF3 on the proliferation and migration of papillary thyroid carcinoma K1 cell]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Zheng X, Zhang T, Wu J, Zhang W, Zhang J, Wang BAbstract OBJECTIVE: To explore the effect on proliferation and invasion of human papillary thyroid carcinoma K1 cells by application of small hairpin RNA (shRNA) silencing TFF3 gene expression....6hHead and NeckThe use of CBCT online correcting technology can significantly reduce the setup errors of VMRT for NPC and improve the treatment effect. [Clinical application of cone-beam CT online correcting technology in volume modulated radiation therapy for nasopharyngeal carcinoma].Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 ;Authors: Qu C, Liang G, Liu GAbstractOBJECTIVE: To investigate the clinical application value of cone-beam CT (CBCT)...6hHead and NeckThere was some correlation between the severity of patients with rhinitis-nasosinusitis and the bronchial asthma and the condition of pulmonary function of patients. Study on the correlation between the severity of chronic rhinosinusitis and bronchial asthma and pulmonary function].Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Jul;29(13):1206-8Authors: Liu YAbstractOBJECTIVE: To explore the correlation between the severity of patients with rhinitis-nasosinusitis...6hHead and NeckApplication of philosophy on comprehensive analysis of adenoid hypertrophy space occupying effect in meticulous adenoidectomy Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Lu Y, Zhang Q, Yu ZAbstractOBJECTIVE: To achieve targeted and meticulous surgery of adenoid hypertrophy, a comprehensive analysis of adenoid hypertrophy space occupying effect and morphological evaluation were conducted and the clinical results...6hHead and NeckRadiation injury of interstitial implantation 125I seeds on normal trachea tissue  of rabbits].Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 ;Authors: Wang H, Chen H, Jia H, Rong D, Lin X, Zhang TAbstractOBJECTIVE: To study the radition injury of tracheal mucous membrane tissue after interstitial implanted radioactive 125I in normal rabbit,improve the safety of clinical application.METHOD:...6hHead and NeckEffect of sildenafil on morphology to noise-induced hearing loss  in guinea pigs].Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 ;Authors: Liang Y, Zhang S, Zhang XAbstractOBJECTIVE: To study the effects of sildenafil on morphology to noise-induced hearing loss in guinea pigs.METHOD: Guinea pigs were randomly divided into control group, noise exposure group...6hHead and NeckAlveolar soft part sarcoma of the larynx Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Xiao H, Yang H, Wang HAbstract Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcomas, this sarcoma occurs rarely in the larynx. Herein, we describe an unusual case of ASPS occurring in the larynx. The patient was a 46-year-old...6hHead and NeckOncocytic carcinoma of the parotid gland Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015Authors: Jiang R, Wang X, Tong LAbstract Approximately 3% of all head and neck neoplasms originate in the parotid gland and less than 1% are oncocytic. We present the rare case of a 63-year-old woman with oncocytic carcinoma of the parotid gland...6hHead and Neck[Cartilaginous tumors of the cricoid Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015;Authors: Qiang X, Xu Y, Chen JAbstract Review a case of cricoid cartilaginous tumour in our hospital in December 2013 retrospectively, which received laryngofissure surgery and was followed up for 1 year. The case is still alive without recurrence....6hHead and Neck[The role of the cerebellum in auditory process and tinnitus]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015;29(13):1231-4Authors: Du Y, Liu J, Kang WAbstractCerebellum connects with each part of the auditory pathway directly or indirectly, forming the anatomical basis for a cerebellar role in auditory process. Functional imaging studies and clinical observations...6hOtoRhinoLaryngology - Alexandros G. SfakianakisVagus Nerve Stimulation During Rehabilitative Training Improves Forelimb Recovery After Chronic Ischemic Stroke in Rats. Vagus Nerve Stimulation During Rehabilitative Training Improves Forelimb Recovery After Chronic Ischemic Stroke in Rats.: Vagus Nerve Stimulation During Rehabilitative Training Improves Forelimb Recovery After Chronic Ischemic Stroke in Rats.Neurorehabil Neural Repair. 2015 Nov 4;Authors: Khodaparast...6hOtoRhinoLaryngology - Alexandros G. SfakianakisEXPOSURE OF THE POPULATION BY RADIODIAGNOSTICS EXPOSURE OF THE SWISS POPULATION BY RADIODIAGNOSTICS: 2013 REVIEW.: EXPOSURE OF THE SWISS POPULATION BY RADIODIAGNOSTICS: 2013 REVIEW.Radiat Prot Dosimetry. 2015 Nov 4;Authors: Le Coultre R, Bize J, Champendal M, Wittwer D, Ryckx N, Aroua A, Trueb P, Verdun FRAbstract In 2013, a nationwide investigation...6hOtoRhinoLaryngology - Alexandros G. SfakianakisSECONDARY NEUTRON DOSES IN A PROTON THERAPY CENTRE. SECONDARY NEUTRON DOSES IN A PROTON THERAPY CENTRE.: SECONDARY NEUTRON DOSES IN A PROTON THERAPY CENTRE.Radiat Prot Dosimetry. 2015 Nov 4;Authors: De Saint-Hubert M, Saldarriaga Vargas C, Van Hoey O, Schoonjans W, De Smet V, Mathot G, Stichelbaut F, Manessi G, Dinar N, Aza E, Cassell C, Silari M, Vanhavere...6hOtoRhinoLaryngology - Alexandros G. SfakianakisCognitive Dysphagia and Effectively Managing The Five Systems Cognitive Dysphagia and Effectively Managing The Five Systems: In order for a person to swallow safely and effectively, five bodily systems must work in coordination. Dysphagia occurs when there is a breakdown in one or more of these systems: neurological (NeuroDys), cognitive (CogDys), muscular (MuscDys),...6hHead and NeckActivate your Email Subscription to: VAERS Monthly Reports You received this message because someone requested an email subscription for alsfakia.head1@blogger.com to a FeedBurner feed. If you did not make this request, please ignore the rest of this message. Hello there, You recently requested an email subscription to VAERS Monthly Reports. We can't...6hOtoRhinoLaryngology - Alexandros G. SfakianakisLichen planus after rabies vaccination Lichen planus after rabies vaccinationFound 514771 cases in entire database - Search Results ...www.rulabinsky.com/.../findfield.php?...Μετάφραση αυτής της σελίδαςAge: 65.0, Onset: 2008-08-11, Days after vaccination: 3 ... On 11 August 2008, 3 daysafter vaccination with ENGERIX B, the subject experienced lichen...6hOtoRhinoLaryngology - Alexandros G. SfakianakisAltered expression of keratin 14 in lesional epidermis of autoimmune skin diseases Altered expression of keratin 14 in lesional epidermis of autoimmune skin diseases: AbstractBackgroundKeratin 14 (K14) is an intermediate filament protein that is mainly expressed in the basal layer of healthy stratified epithelia. K14 has been identified as an autoantigen in the autoimmune-mediated...6hOtoRhinoLaryngology - Alexandros G. SfakianakisRequirement for vitamin D supplementation in patients using photoprotection: variations in vitamin D levels and bone formation markers Requirement for vitamin D supplementation in patients using photoprotection: variations in vitamin D levels and bone formation markers: AbstractBackgroundAvoiding sun exposure is obligatory in photodermatoses; however, the need for oral supplementation with vitamin D appears unrecognized. The aim of...6hOtoRhinoLaryngology - Alexandros G. SfakianakisContact allergy in cheilitis Contact allergy in cheilitis: AbstractBackgroundRecalcitrant non-actinic cheilitis may indicate contact allergy.ObjectivesThis study aimed to determine the prevalence of allergic contact cheilitis (ACC) in patients with non-actinic cheilitis and to identify the most relevant allergens.MethodsWe used...6hOtoRhinoLaryngology - Alexandros G. SfakianakisESCC : Relationship Between the Size of Metastatic Lymph Nodes and PET/CT Findings Relationship Between the Size of Metastatic Lymph Nodes and Positron Emission Tomographic/Computer Tomographic Findings in Patients with Esophageal Squamous Cell Carcinoma: AbstractBackgroundWe measured the sizes of metastatic lymph nodes and the relationships thereof by 18F-fluorodeoxyglucose positron...6hOtoRhinoLaryngology - Alexandros G. SfakianakisPrevention of Esophageal Stricture After Endoscopic Submucosal Dissection: A Systematic Review Prevention of Esophageal Stricture After Endoscopic Submucosal Dissection: A Systematic Review: AbstractBackgroundEndoscopic submucosal dissection (ESD) is rapidly becoming a favored method for removing early esophageal cancer, but the residual defects can be complicated with strictures that require...6hOtoRhinoLaryngology - Alexandros G. SfakianakisSurgeons OverSeas Assessment of Surgical Need (SOSAS) Surgeons OverSeas Assessment of Surgical Need (SOSAS) Uganda: Update for Household Survey: AbstractIntroductionThe first step in improving surgical care delivery in low- and middle-income countries (LMICs) is quantifying surgical need. The Surgeons OverSeas Assessment of Surgical Need (SOSAS) is a validated...6hOtoRhinoLaryngology - Alexandros G. SfakianakisGraph theory analysis of complex brain networks: new concepts in brain mapping applied to neurosurgery Graph theory analysis of complex brain networks: new concepts in brain mapping applied to neurosurgery: Journal of Neurosurgery, Ahead of Print. Neuroanatomy has entered a new era, culminating in the search for the connectome, otherwise known as the brain’s wiring diagram. While this approach has led...6hOtoRhinoLaryngology - Alexandros G. SfakianakisThe far-lateral approach: destruction of the condyle does not necessarily result in clinically evident craniovertebral junction instability The far-lateral approach: destruction of the condyle does not necessarily result in clinically evident craniovertebral junction instability: Journal of Neurosurgery, Ahead of Print. OBJECT Far-lateral or extreme-lateral approaches to the skull base allow access to the lateral and anterior portion of...6hOtoRhinoLaryngology - Alexandros G. SfakianakisIntraarterial administration of norcantharidin attenuates ischemic stroke damage Intraarterial administration of norcantharidin attenuates ischemic stroke damage in rodents when given at the time of reperfusion: novel uses of endovascular capabilities: Journal of Neurosurgery, Ahead of Print. OBJECT Matrix metalloprotease-9 (MMP-9) plays a critical role in infarct progression, blood-brain...6hOtoRhinoLaryngology - Alexandros G. SfakianakisChronic nasal dysfunction in children: Allergic rhinitis? Infectious? What to do if neither? Chronic nasal dysfunction in children: Allergic rhinitis? Infectious? What to do if neither?: Purpose of review: To review challenges in the diagnosis, work-up, and management of healthy children who present to the otolaryngologist with nasal dysfunction. Common symptoms include chronic nasal congestion,...6hOtoRhinoLaryngology - Alexandros G. SfakianakisViral laryngitis: a mimic and a monster Viral laryngitis: a mimic and a monster – range, presentation, management: Purpose of review: The purpose of this review is to highlight recent literature relating to the diagnosis and treatment of some less common forms of viral laryngitis. The main conditions addressed in this review are chronic cough...6hOtoRhinoLaryngology - Alexandros G. SfakianakisPediatric otolaryngology, molecular diagnosis of hereditary hearing loss: next-generation sequencing approach Pediatric otolaryngology, molecular diagnosis of hereditary hearing loss: next-generation sequencing approach: Purpose of review: Sensorineural hearing loss (SNHL) is the most common sensory birth defect. The purpose of this article is to review the advances in next-generation sequencing (NGS) and molecular...6hOtoRhinoLaryngology - Alexandros G. SfakianakisThe role of biofilm in chronic laryngitis and in head and neck cancer The role of biofilm in chronic laryngitis and in head and neck cancer: Purpose of review: The importance of bacterial biofilm in the human body, both when associated in chronic infections and as the default mode of microbial growth in the normal flora, has been understood during the last two decades....6hOtoRhinoLaryngology - Alexandros G. SfakianakisAdult obstructive sleep apnoea and the larynx Adult obstructive sleep apnoea and the larynx: Purpose of review: The review examines current evidence and thinking regarding the relationship between the larynx and obstructive sleep apnoea (OSA) in adults.Recent findings: Drug-induced sleep endoscopy has an emerging role in the identification of laryngeal...6hOtoRhinoLaryngology - Alexandros G. SfakianakisSwallowing assessment and management pre and post head and neck cancer treatment Swallowing assessment and management pre and post head and neck cancer treatment: Purpose of review: Head and neck cancer (HNC) imposes significant structural, functional, and cosmetic burdens upon those affected. Although advances in multimodality organ preservation therapy have assisted in ameliorating...6hOtoRhinoLaryngology - Alexandros G. SfakianakisManagement of oropharyngeal neurogenic dysphagia in adults Management of oropharyngeal neurogenic dysphagia in adults: Purpose of review: This article reviews recent literature in the management of neurogenic oropharyngeal dysphagia (OPD) including assessment processes and treatments, with a specific focus on OPD as a result of stroke and Parkinson's disease.Recent...6hOtoRhinoLaryngology - Alexandros G. SfakianakisPerspectives in the reconstruction of paediatric facial paralysis Perspectives in the reconstruction of paediatric facial paralysis: Purpose of review: In this review article, aimed at those likely to encounter but relatively unfamiliar with paediatric facial paralysis, we summarize reconstructive options in its surgical management.Recent findings: The article looks...6hOtoRhinoLaryngology - Alexandros G. SfakianakisCaustic oesophagitis in children Caustic oesophagitis in children: prevalence, the corrosive agents involved, and management from primary care through to surgery: Purpose of review: Caustic substance ingestion (CSI) remains a major health issue, particularly in developing countries, where laws are not effectively enforced. This review...6hOtoRhinoLaryngology - Alexandros G. SfakianakisPediatric tracheotomy decannulation Pediatric tracheotomy decannulation: a protocol for success: Purpose of review: Pediatric tracheotomy is a common procedure. Given the risk of morbidity and mortality associated with long-term placement, it is imperative that decannulation is considered once the indication for tracheotomy placement...6hOtoRhinoLaryngology - Alexandros G. SfakianakisInfective oesophagitis Infective oesophagitis: epidemiology, cause, diagnosis and treatment options: Purpose of review: This review summarizes recent literature pertaining to infectious oesophagitis.Recent findings: Infectious oesophagitis is an uncommon condition of the oesophagus caused by viral, bacterial or fungal agents....6hHead and NeckSmoking affects quality of life in patients with oral squamous cell carcinomas. Authors: Krüskemper G, Handschel JAbstractSmoking is a causative factor in oral squamous cell carcinomas (SCC). Unfortunately, only poor data exist regarding the quality of life of smokers vs non-smokers with SCC. The purpose of this study is to show a correlation between variables for comprehensive...6hOtoRhinoLaryngology - Alexandros G. SfakianakisSolar ultraviolet A and B radiation in relation to vitamin D production and risk for skin cancer Daily, seasonal, and latitudinal variations in solar ultraviolet A and B radiation in relation to vitamin D production and risk for skin cancer: AbstractBackgroundSolar ultraviolet (UV) radiation varies with latitude, time of day, and season. Both spectral UV composition and ambient UV dose lead to different...6hOtoRhinoLaryngology - Alexandros G. SfakianakisNovel Concept of Attaching Endoscope Holder to Microscope for Two Handed Endoscopic Tympanoplasty Novel Concept of Attaching Endoscope Holder to Microscope for Two Handed Endoscopic Tympanoplasty: AbstractThe well established techniques in tympanoplasty are routinely performed with operating microscopes for many decades now. Endoscopic ear surgeries provide minimally invasive approach to the middle...6hHead and NeckExhaled NO: Determinants and Clinical Application in Children With Allergic Airway Disease. Authors: Kim HB, Eckel SP, Kim JH, Gilliland FDAbstract Nitric oxide (NO) is endogenously released in the airways, and the fractional concentration of NO in exhaled breath (FeNO) is now recognized as a surrogate marker of eosinophilic airway inflammation that can be measured using a noninvasive...6hHead and NeckPrevalence, Severity, and Treatment of Recurrent Wheezing During the First Year of Life: A Cross-Sectional Study of 12,405 Latin American Infants. Allergy Asthma Immunol Res. 2016 Jan;8(1):22-31Authors: Mallol J, Solé D, Garcia-Marcos L, Rosario N, Aguirre V, Chong H, Urrutia-Pereira M, Szulman G, Niederbacher J, Arruda-Chavez E, Toledo E, Sánchez L, Pinchak C, EISL Latin American GroupAbstract PURPOSE: This study aimed to determine the...6hHead and NeckGIS-based Association Between PM10 and Allergic Diseases in Seoul: Implications for Health and Environmental Policy. Allergy Asthma Immunol Res. 2016 Jan;8(1):32-40Authors: Seo S, Kim D, Min S, Paul C, Yoo Y, Choung JTAbstractPURPOSE: The role of PM10 in the development of allergic diseases remains controversial among epidemiological studies, partly due to the inability to control for spatial variations in large-scale...6hHead and NeckThe Interaction Between Prenatal Exposure to Home Renovation and Reactive Oxygen Species Genes in Cord Blood IgE Response is Modified by Maternal Atopy. Allergy Asthma Immunol Res. 2016 Jan;8(1):41-48Authors: Yu J, Ahn K, Shin YH, Kim KW, Suh DI, Yu HS, Kang MJ, Lee KS, Hong SA, Choi KY, Lee E, Yang SI, Seo JH, Kim BJ, Kim HB, Lee SY, Choi SJ, Oh SY, Kwon JY, Lee KJ, Park HJ, Lee PR, Won HS, Hong SJ, COCOA study groupAbstract PURPOSE: Although...6hHead and NeckRelationship Between Allergic Rhinitis and Mental Health Relationship Between Allergic Rhinitis and Mental Health in the General Korean Adult Population.Allergy Asthma Immunol Res. 2016 Jan;8(1):49-54Authors: Kim DH, Han K, Kim SWAbstract PURPOSE: This study was conducted to evaluate the association between AR and mental health status in the general...6hHead and NeckEffect of Amino Acid Polymorphisms of House Dust Mite Der p 2 Variants on Allergic Sensitization. Allergy Asthma Immunol Res. 2016 Jan;8(1):55-62Authors: Tanyaratsrisakul S, Jirapongsananuruk O, Kulwanich B, Hales BJ, Thomas WR, Piboonpocanun SAbstract PURPOSE: The sequence variations of the Der p 2 allergen of Dermatophagoides pteronyssinus diverge along 2 pathways with particular amino...6hHead and NeckAlternaria Induces Production of Thymic Stromal Lymphopoietin in Nasal Fibroblasts Through Toll-like Receptor 2. Allergy Asthma Immunol Res. 2016 Jan;8(1):63-68Authors: Shin SH, Kim YH, Jin HS, Kang SHAbstract PURPOSE: Chronic rhinosinusitis with nasal polyps is a chronic inflammatory disease with markedly increased eosinophils, Th2-type lymphocytes, fibroblasts, and goblet cells. Fungi are commonly associated...6hHead and NeckAlternative Method for Primary Nasal Epithelial Cell Culture Using Intranasal Brushing and Feasibility for the Study of Epithelial Functions in Allergic Rhinitis. Allergy Asthma Immunol Res. 2016 Jan;8(1):69-78Authors: Park DY, Kim S, Kim CH, Yoon JH, Kim HJAbstract PURPOSE: Although differentiated normal human nasal epithelial (NHNE) cells can be used to study the role of human nasal epithelium, there is a need for effective culture models of nasal epithelium...6hHead and NeckPrevalence of Atopic Dermatitis Prevalence of Atopic Dermatitis in Korean Children Based on Data From the 2008-2011 Korean National Health and Nutrition Examination Survey.Allergy Asthma Immunol Res. 2016 Jan;8(1):79-83Authors: Lee JH, Han KD, Kim KM, Park YG, Lee JY, Park YMAbstractPopulation-based studies of atopic dermatitis (AD)...6hOtoRhinoLaryngology - Alexandros G. SfakianakisThe Prevention Of Decline in Cognition After Stroke Trial (PODCAST) Baseline characteristics, analysis plan and report on feasibility for the Prevention Of Decline in Cognition After Stroke Trial (PODCAST): Background:A common complication after stroke is development of cognitive impairment and dementia. However, effective strategies for reducing the risk of developing...6hOtoRhinoLaryngology - Alexandros G. SfakianakisAntimicrobial photodynamic therapy Antimicrobial photodynamic therapy minimizes the deleterious effect of nicotine in female rats with induced periodontitis: AbstractThe aim of this study was to compare the use of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of experimentally...6hOtoRhinoLaryngology - Alexandros G. SfakianakisPediatric skull base reconstruction: Tunneled temporoparietal fascia flap Pediatric skull base reconstruction: case report of a tunneled temporoparietal fascia flap: Journal of Neurosurgery: Pediatrics, Ahead of Print. The authors of this report present a pediatric case involving the use of a tunneled temporoparietal fascia flap to reconstruct a skull base defect for a multiply...6hOtoRhinoLaryngology - Alexandros G. SfakianakisParaplegia after contrast media application Paraplegia after contrast media application: a transient or devastating rare complication? Case report: Journal of Neurosurgery: Spine, Ahead of Print. The authors report the case of a 76-year-old man with a spinal dural arteriovenous fistula. The patient suffered from sudden repeated reversible paraplegia...6hOtoRhinoLaryngology - Alexandros G. SfakianakisSkin cancer spinal metastases A systematic review of clinical outcomes for patients diagnosed with skin cancer spinal metastases: Journal of Neurosurgery: Spine, Ahead of Print. OBJECT Surgical procedures and/or adjuvant therapies are effective modalities for the treatment of symptomatic spinal metastases. However, clinical results...6hOtoRhinoLaryngology - Alexandros G. SfakianakisThe functional plasticity of adult cortex Intraoperative mapping during repeat awake craniotomy reveals the functional plasticity of adult cortex: Journal of Neurosurgery, Ahead of Print. OBJECT To avoid iatrogenic injury during the removal of intrinsic cerebral neoplasms such as gliomas, direct electrical stimulation (DES) is used to identify...6hOtoRhinoLaryngology - Alexandros G. SfakianakisIntramedullary meningeal melanocytoma of intermediate grade at T9–10 The GNAQ in the haystack: intramedullary meningeal melanocytoma of intermediate grade at T9–10 in a 58-year-old woman: Journal of Neurosurgery, Ahead of Print. Meningeal melanocytomas are rare tumors. They are derived from leptomeningeal melanocytes and predominantly occur along the spine and the posterior...6hOtoRhinoLaryngology - Alexandros G. SfakianakisPreoperative chemotherapy and corticosteroids: independent predictors of cranial surgical-site infections Preoperative chemotherapy and corticosteroids: independent predictors of cranial surgical-site infections: Journal of Neurosurgery, Ahead of Print. OBJECT Preoperative corticosteroids and chemotherapy are frequently prescribed for patients undergoing cranial neurosurgery but may pose a risk of postoperative...6hOtoRhinoLaryngology - Alexandros G. SfakianakisCalvarial slope affecting accuracy of Ghajar Guide technique for ventricular catheter placement Calvarial slope affecting accuracy of Ghajar Guide technique for ventricular catheter placement: Journal of Neurosurgery, Ahead of Print. OBJECT The Ghajar Guide technique is used to direct a ventricular catheter at a 90° angle to the skull surface at Kocher’s point. However, the human calvaria is not...6hOtoRhinoLaryngology - Alexandros G. SfakianakisConvection-enhanced delivery of sorafenib and suppression of tumor progression in a murine model of brain melanoma through the inhibition of signal transducer and activator of transcription 3 Convection-enhanced delivery of sorafenib and suppression of tumor progression in a murine model of brain melanoma through the inhibition of signal transducer and activator of transcription 3: Journal of Neurosurgery, Ahead of Print. OBJECT Despite recent advances, metastatic melanoma remains a terminal...6hOtoRhinoLaryngology - Alexandros G. SfakianakisDoes immunotherapy increase the rate of radiation necrosis after radiosurgical treatment of brain metastases? Does immunotherapy increase the rate of radiation necrosis after radiosurgical treatment of brain metastases?: Journal of Neurosurgery, Ahead of Print. OBJECT Radiation necrosis (RN), or its imaging equivalent, treatment-related imaging changes (TRIC), is an inflammatory reaction to high-dose radiation...6hOtoRhinoLaryngology - Alexandros G. SfakianakisAuditory cortical activity to different voice onset times in cochlear implant users Auditory cortical activity to different voice onset times in cochlear implant users: Cochlear implants (CI) effectively provide hearing sensation for adults and children with severe-to-profound hearing loss (Zeng, 2004). Although CI technology continues to improve, there remains significant variability...6hOtoRhinoLaryngology - Alexandros G. SfakianakisThe Loudness Dependence of Auditory Evoked Potentials (LDAEP) in individuals at risk for developing bipolar disorders and schizophrenia The Loudness Dependence of Auditory Evoked Potentials (LDAEP) in individuals at risk for developing bipolar disorders and schizophrenia: The loudness dependence of auditory evoked potentials (LDAEP) has been described as an indicator of serotonergic activity in humans (Hegerl et al., 2001; Hegerl and...6hOtoRhinoLaryngology - Alexandros G. SfakianakisAn ERP Source Imaging Study of the Oddball Task in Children with Attention Deficit/Hyperactivity Disorder An ERP Source Imaging Study of the Oddball Task in Children with Attention Deficit/Hyperactivity Disorder: Early theoretical models of Attention-Deficit/Hyperactivity Disorder (ADHD) (Barkley, 1997) have emphasized deficiencies in executive processes, closely related to prefrontal-striatal circuits (Castellanos,...6hOtoRhinoLaryngology - Alexandros G. SfakianakisThe prognostic value of sleep patterns in disorders of consciousness in the sub-acute phase The prognostic value of sleep patterns in disorders of consciousness in the sub-acute phase: The outcome of patients with disorders of consciousness (DOCs) remains difficult to predict. A key factor to consider is the duration of the DOC, as the prognosis worsens the longer the patient is in the condition...6hOtoRhinoLaryngology - Alexandros G. SfakianakisHigh hemoglobin A1c levels within the non-diabetic range are associated with the risk of all cancers High hemoglobin A1c levels within the non-diabetic range are associated with the risk of all cancers: ABSTRACTPrevious studies have reported associations between diabetes and cancer risk. However, specific association of hemoglobin A1c (HbA1c) levels with cancer risk remains inconclusive. We followed...7hOtoRhinoLaryngology - Alexandros G. SfakianakisInducing Oncoprotein Degradation to Improve Targeted Cancer Therapy Inducing Oncoprotein Degradation to Improve Targeted Cancer Therapyστο ScienceDirect Publication: NeoplasiaSource:Neoplasia, Volume 17, Issue 9Author(s): Dipankar Ray, Kyle C. Cuneo, Alnawaz Rehemtulla, Theodore S. Lawrence, Mukesh K. NyatiOver the past decade, inhibition of the kinase activities of...7hOtoRhinoLaryngology - Alexandros G. SfakianakisAdverse events following immunisation Factors affecting the causality assessment of adverse events following immunisation in paediatric clinical trials: An online surveyστο ScienceDirect Publication: VaccinePublication date: Available online 6 November 2015Source:VaccineAuthor(s): Merryn Voysey, Rahele T. Fard, Yama Farooq, Paul T. Heath,...7hOtoRhinoLaryngology - Alexandros G. SfakianakisProtecting Newborns Against Pertussis: Pertussis is a potentially severe respiratory disease, which affects all age groups from young infants to older adults and is responsible for an estimated 195,000 deaths Protecting Newborns Against Pertussis: Treatment and Prevention Strategies: AbstractPertussis is a potentially severe respiratory disease, which affects all age groups from young infants to older adults and is responsible for an estimated 195,000 deaths occurred globally in 2008. Active research is ongoing...7hOtoRhinoLaryngology - Alexandros G. SfakianakisThrombocytosis and Raised CRP Levels Predicts Advanced Stage in Esophageal Carcinoma Thrombocytosis and Raised CRP Levels Predicts Advanced Stage in Esophageal Carcinoma: AbstractPurposeThe significance of thrombocytosis and raised C-reactive protein (CRP) as prognostic markers in esophageal cancer is unclear.MethodsWe prospectively studied 50 consecutive patients with esophageal cancer...7hOtoRhinoLaryngology - Alexandros G. SfakianakisRole of Msi1 and MAML1 in Regulation of Notch Signaling Pathway in Patients with Esophageal Squamous Cell Carcinoma Role of Msi1 and MAML1 in Regulation of Notch Signaling Pathway in Patients with Esophageal Squamous Cell Carcinoma: AbstractPurposeDevelopmental pathways such as Wnt and Notch are involved in different cellular functions from the cell cycle regulation to self-renewal. Therefore, aberrations in these...7hOtoRhinoLaryngology - Alexandros G. SfakianakisPediatric schwannomatosis Pediatric schwannomatosis, a rare but distinct form of neurofibromatosis: AbstractSchwannomatosis is the third major form of neurofibromatosis, distinct from neurofibromatosis type 2 (NF2) and type 1 (NF1). This condition is rare with a variable phenotypic presentation and complex molecular and genetic...7hOtoRhinoLaryngology - Alexandros G. SfakianakisReduction of isolated zygomatic arch fractures : C-arm as intraoperative control C-arm as intraoperative control in reduction of isolated zygomatic arch fractures: a randomized clinical trial: AbstractPurposeIsolated zygomatic arch fractures (IZAFs) are habitually reduced at a distance, via a temporal approach. Open reductions are not recommended due to the associated morbidity and...7hOtoRhinoLaryngology - Alexandros G. SfakianakisFolic acid supplementation at lower doses increases oxidative stress resistance and longevity Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans: AbstractFolic acid (FA) is an essential nutrient that the human body needs but cannot be synthesized on its own. Fortified foods and plant food sources such as green leafy vegetables,...7hOtoRhinoLaryngology - Alexandros G. SfakianakisThe Hendrich II Fall Risk Model Evaluation of Reliability and Validity of the Hendrich II Fall Risk Model in a Chinese Hospital Population: by Congcong Zhang, Xinjuan Wu, Songbai Lin, Zhaoxia Jia, Jing CaoTo translate, validate and examine the reliability and validity of a Chinese version of the Hendrich II Fall risk Model (HFRM) in...7hOtoRhinoLaryngology - Alexandros G. SfakianakisA pediatric patient with meningitis identified by metagenomic next-generation sequencing in cerebrospinal fluid Fatal Psychrobacter sp. infection in a pediatric patient with meningitis identified by metagenomic next-generation sequencing in cerebrospinal fluid: AbstractThe genus Psychrobacter contains environmental, psychrophilic and halotolerant gram-negative bacteria considered rare opportunistic pathogens in...7hOtoRhinoLaryngology - Alexandros G. SfakianakisForebrain-independent generation of hyperthermic convulsions in infants Forebrain-independent generation of hyperthermic convulsions in infant rats: SummaryFebrile seizures are the most common type of convulsive events in children. It is generally assumed that the generalization of these seizures is a result of brainstem invasion by the initial limbic seizure activity. Using...7hOtoRhinoLaryngology - Alexandros G. SfakianakisCopper surfaces are associated with significantly lower concentrations of bacteria  on selected surfaces within a pediatric intensive care unitστο ScienceDirect Publication: American Journal of Infection ControlPublication date: Available online 6 November 2015Source:American Journal of Infection ControlAuthor(s): Michael G. Schmidt, Bettina von Dessauer, Carmen Benavente, Dona Benadof,...7hOtoRhinoLaryngology - Alexandros G. SfakianakisMicrobial contamination of anesthetic syringes  in relation to different handling habitsστο ScienceDirect Publication: American Journal of Infection ControlPublication date: Available online 7 November 2015Source:American Journal of Infection ControlAuthor(s): Florian Heid, Carolin Bender, Hendrik Gervais, Joachim Schmeck, Wolfgang Kohnen, Rüdiger...7hOtoRhinoLaryngology - Alexandros G. SfakianakisContinuous bed motion versus traditional bed position whole-body PET/CT imaging A randomized, double-blind, crossover comparison of novel continuous bed motion versus traditional bed position whole-body PET/CT imaging: AbstractPurposeContinuous bed motion has recently been introduced for whole-body PET/CT, and represents a paradigm shift towards individualized and flexible acquisition...8hOtoRhinoLaryngology - Alexandros G. SfakianakisPrenatal education for group B streptococcus prevention Increasing postpartum rate of vaccination with tetanus, diphtheria, and acellular pertussis vaccine by incorporating pertussis cocooning information into prenatal education for group B streptococcus preventionστο ScienceDirect Publication: VaccinePublication date: Available online 6 November 2015Source:VaccineAuthor(s):...8hOtoRhinoLaryngology - Alexandros G. SfakianakisEvodiamine inhibits the migration and invasion of nasopharyngeal carcinoma cells in vitro via repressing MMP-2 expression Evodiamine inhibits the migration and invasion of nasopharyngeal carcinoma cells in vitro via repressing MMP-2 expression: AbstractPurposeEvodiamine is one of active alkaloids isolated from the traditional Chinese medicine Evodia rutaecarpa Bentham and has various pharmacological properties. In this...8hOtoRhinoLaryngology - Alexandros G. SfakianakisRegional brain responses associated with thermogenic and psychogenic sweating events in humans Regional brain responses associated with thermogenic and psychogenic sweating events in humans: Sweating events occur in response to mental stress (psychogenic) or with increased body temperature (thermogenic). We previously found that both were linked to activation of common brain stem regions, suggesting...8hOtoRhinoLaryngology - Alexandros G. SfakianakisNormalization in human somatosensory cortex : Functional magnetic resonance imaging (fMRI) was used to measure activity in human somatosensory cortex and to test for cross-digit suppression Normalization in human somatosensory cortex: Functional magnetic resonance imaging (fMRI) was used to measure activity in human somatosensory cortex and to test for cross-digit suppression. Subjects received stimulation (vibration of varying amplitudes) to the right thumb (target) with or without concurrent...8hOtoRhinoLaryngology - Alexandros G. SfakianakisCoaggregation occurs between microorganisms isolated from different environments Coaggregation occurs between microorganisms isolated from different environments: Coaggregation, the specific recognition and adherence of different microbial species, is thought to enhance biofilm formation. To date, no studies have focused on the ability of microorganisms isolated from a broad range...8hOtoRhinoLaryngology - Alexandros G. SfakianakisUse of ward closure to control outbreaks among hospitalized patients in acute care settings: a systematic review Use of ward closure to control outbreaks among hospitalized patients in acute care settings: a systematic review: Background:Though often used to control outbreaks, the efficacy of ward closure is unclear. This systematic review sought to identify studies defining and describing ward closure in outbreak...8hOtoRhinoLaryngology - Alexandros G. SfakianakisArgonaute 2 and nasopharyngeal carcinoma : The genetic polymorphism in AGO2 may be a risk factor for the advanced lymph node metastasis of NPC Argonaute 2 and nasopharyngeal carcinoma: a genetic association study and functional analysis: AbstractBackgroundArgonaute 2 (AGO2), a central component of RNA-induced silencing complex, plays critical roles in cancer. We examined whether the single nucleotide polymorphisms (SNPs) of AGO2 were related...8hOtoRhinoLaryngology - Alexandros G. SfakianakisPanhypopituitarism : Pituitary metastasis of hepatocellular carcinoma Pituitary metastasis of hepatocellular carcinoma presenting with panhypopituitarism: a case report: AbstractBackgroundMetastasis to the pituitary gland is extremely rare and is often detected incidentally by symptoms associated with endocrine dysfunction. Breast and lung cancer are the most common primary...8hOtoRhinoLaryngology - Alexandros G. SfakianakisOverdiagnosis and screening for thyroid cancer A qualitative study of women’s views on overdiagnosis and screening for thyroid cancer in Korea: AbstractBackgroundThe incidence of thyroid cancer in Korea has increased by about 25 % every year for the past 10 years. This increase is largely due to a rising incidence in papillary thyroid cancer, which...8hOtoRhinoLaryngology - Alexandros G. SfakianakisSimultaneous determination of human papillomavirus infections and viral loads Development of a fluorescence–based multiplex genotyping method for simultaneous determination of human papillomavirus infections and viral loads: AbstractBackgroundPersistent high-risk human papillomavirus (HPV) infection is correlated with an increased risk of developing intraepithelial lesion or malignancy...8hOtoRhinoLaryngology - Alexandros G. SfakianakisHNC : MicroRNA-363 targets myosin 1B to reduce cellular migration MicroRNA-363 targets myosin 1B to reduce cellular migration in head and neck cancer: AbstractBackgroundSquamous cell carcinoma of the head and neck (SCCHN) remains a prevalent and devastating disease. Recently, there has been an increase in SCCHN cases that are associated with high-risk human papillomavirus...8hOtoRhinoLaryngology - Alexandros G. SfakianakisSystemic exposure to monoethylglycinexylidide in extensive tumescent liposuction Systemic exposure to monoethylglycinexylidide in extensive tumescent liposuction: AbstractBackgroundPlastic surgery patients frequently request extensive liposuction on approximately 30 % of the total body surface area, which indicates that the total dose of lidocaine used might exceed the recommended...8hOtoRhinoLaryngology - Alexandros G. SfakianakisInfrared technology to improve efficacy of venous access in burns population Infrared technology to improve efficacy of venous access in burns population: AbstractBackgroundObtaining venous access in the burn population is challenging both in the acute and elective surgical settings. In paediatric burns, this is further compounded by smaller veins, thicker subcutaneous fat and...8hOtoRhinoLaryngology - Alexandros G. SfakianakisCombination of photodynamic therapy and specific immunotherapy efficiently eradicates established tumors Combination of photodynamic therapy and specific immunotherapy efficiently eradicates established tumors: Purpose: The efficacy of immunotherapy against advanced cancer may be improved by combination strategies. Photodynamic Therapy (PDT) is a local tumor ablation method based on localized activation...8hOtoRhinoLaryngology - Alexandros G. SfakianakisSonidegib in Advanced Basal Cell Carcinoma Patients Resistant to Vismodegib An Investigator-Initiated Open-label Trial of Sonidegib in Advanced Basal Cell Carcinoma Patients Resistant to Vismodegib: Purpose: To assess the tumor response to the smoothened (SMO) inhibitor, sonidegib (LDE225), in patients with an advanced basal cell carcinoma (BCC) resistant to treatment with vismodegib...8hOtoRhinoLaryngology - Alexandros G. SfakianakisThe Influence of Head Impact Threshold for Reporting Data in Contact and Collision Sports: Systematic Review and Original Data Analysis The Influence of Head Impact Threshold for Reporting Data in Contact and Collision Sports: Systematic Review and Original Data Analysis: AbstractBackgroundHead impacts and resulting head accelerations cause concussive injuries. There is no standard for reporting head impact data in sports to enable comparison...8hOtoRhinoLaryngology - Alexandros G. SfakianakisA User’s Guide to Local Perforator Flap Reconstruction in a post-conflict Setting A User’s Guide to Local Perforator Flap Reconstruction in a post-conflict Setting: Local perforator flaps are a versatile source of vascularized tissue(1-4). A “user’s guide” has been proposed to enhance the outcome of these reliable flaps when performed in a post conflict environment. This is based...8hOtoRhinoLaryngology - Alexandros G. SfakianakisReal-time safety surveillance of seasonal influenza vaccines in children Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015.: Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015.Euro Surveill. 2015 Oct 29;20(43)Authors: Pillsbury A, Cashman P, Leeb A, Regan A, Westphal D, Snelling T, Blyth C, Crawford...8hOtoRhinoLaryngology - Alexandros G. SfakianakisSpatial methods for infectious disease outbreak investigations Spatial methods for infectious disease outbreak investigations: systematic literature review.: Spatial methods for infectious disease outbreak investigations: systematic literature review.Euro Surveill. 2015 Oct 1;20(39)Authors: Smith CM, Le Comber SC, Fry H, Bull M, Leach S, Hayward ACAbstract ...8hOtoRhinoLaryngology - Alexandros G. SfakianakisUptake and impact of vaccinating school age children against influenza during a season with circulation of drifted influenza A and B strains, England, 2014/15. Uptake and impact of vaccinating school age children against influenza during a season with circulation of drifted influenza A and B strains, England, 2014/15.: Uptake and impact of vaccinating school age children against influenza during a season with circulation of drifted influenza A and B strains,...8hOtoRhinoLaryngology - Alexandros G. SfakianakisRaw milk consumption : Outbreak of Yersinia pseudotuberculosis O:1 infection Outbreak of Yersinia pseudotuberculosis O:1 infection associated with raw milk consumption, Finland, spring 2014.: Outbreak of Yersinia pseudotuberculosis O:1 infection associated with raw milk consumption, Finland, spring 2014.Euro Surveill. 2015 Oct 8;20(40)Authors: Pärn T, Hallanvuo S, Salmenlinna...8hOtoRhinoLaryngology - Alexandros G. SfakianakisTick-borne encephalitis Tick-borne encephalitis in north-east Italy: a 14-year retrospective study, January 2000 to December 2013.: Tick-borne encephalitis in north-east Italy: a 14-year retrospective study, January 2000 to December 2013.Euro Surveill. 2015 Oct 8;20(40)Authors: Rezza G, Farchi F, Pezzotti P, Ruscio M, Lo Presti...8hOtoRhinoLaryngology - Alexandros G. SfakianakisHuman Middle East respiratory syndrome (MERS)-coronavirus infection. Comparison of serological assays in human Middle East respiratory syndrome (MERS)-coronavirus infection.: Comparison of serological assays in human Middle East respiratory syndrome (MERS)-coronavirus infection.Euro Surveill. 2015 Oct 15;20(41)Authors: Park SW, Perera RA, Choe PG, Lau EH, Choi SJ, Chun...8hOtoRhinoLaryngology - Alexandros G. SfakianakisSafety of house dust mite sublingual immunotherapy standardized quality tablet in children allergic to house dust mites Safety of house dust mite sublingual immunotherapy standardized quality tablet in children allergic to house dust mites: Sublingual immunotherapy (SLIT) tablets could be an important alternative to subcutaneous immunotherapy for house dust mite (HDM) allergy in children.AbstractBackgroundSublingual immunotherapy...8hOtoRhinoLaryngology - Alexandros G. SfakianakisPioneers in allergy and immunology: John Edward Salvaggio, MD, MACP, 1933–1999 Pioneers in allergy and immunology: John Edward Salvaggio, MD, MACP, 1933–1999: It is hard to sum up a life well lived in a few words, especially one with as many accomplishments as that of Dr John Salvaggio (Fig 1). Yes, he is among a relatively small group of those internationally known clinician-investigators...8hOtoRhinoLaryngology - Alexandros G. SfakianakisSurgical resection of unilateral thalamic tumors in adults: approaches and outcomes Surgical resection of unilateral thalamic tumors in adults: approaches and outcomes: Background:The thalamic tumors were less common in adults and this study aimed to determine the clinical features, surgical approaches, and outcomes of adult thalamic tumors, which have not been well-described in the...8hOtoRhinoLaryngology - Alexandros G. SfakianakisSimulation-Based Cryosurgery Training Variable Insertion Depth Planning in Prostate Cryosurgery: A proof-of-concept for an advanced-level computerized training tool for cryosurgery is demonstrated, based on three-dimensional cryosurgery simulations and a variable insertion depth strategy for cryoprobes. The objective for system development...8hOtoRhinoLaryngology - Alexandros G. SfakianakisGlucagon-like peptide 2 counteracts the mucosal damage and the neuropathy induced by chronic treatment with cisplatin in the mouse gastric fundus Glucagon-like peptide 2 counteracts the mucosal damage and the neuropathy induced by chronic treatment with cisplatin in the mouse gastric fundus: AbstractBackgroundGlucagon-like peptide-2 (GLP-2) is a pleiotropic hormone synthesized and secreted by the enteroendocrine ‘L’ cells able to exert intestine-trophic...8hOtoRhinoLaryngology - Alexandros G. SfakianakisMaximum upper esophageal sphincter (UES) admittance: a non-specific marker of UES dysfunction Maximum upper esophageal sphincter (UES) admittance: a non-specific marker of UES dysfunction: AbstractBackgroundAssessment of upper esophageal sphincter (UES) motility is challenging, as functionally, UES relaxation and opening are distinct. We studied novel parameters, UES admittance (inverse of nadir...8hOtoRhinoLaryngology - Alexandros G. SfakianakisCause-specific excess mortality in patients treated for cancer of the oral cavity and oropharynx: A population-based study Cause-specific excess mortality in patients treated for cancer of the oral cavity and oropharynx: A population-based study: Squamous cell carcinomas of the oral cavity (OC) and oropharynx (OP) still carry a relatively poor prognosis. Despite some successes of optimized multimodality therapy in improving...8hOtoRhinoLaryngology - Alexandros G. SfakianakisImproved prognosis for patients with oral cavity squamous cell carcinoma: Analysis of the National Cancer Database 1998–2006 Improved prognosis for patients with oral cavity squamous cell carcinoma: Analysis of the National Cancer Database 1998–2006: Oral cavity cancer is the fifteenth most common malignancy worldwide [1], and accounted for over 28,000 new cancer diagnoses and 5800 cancer-related deaths in the United States...8hOtoRhinoLaryngology - Alexandros G. SfakianakisBacterial diversity in temporomandibular joint synovial fluid Juvenile idiopathic arthritis and rheumatoid arthritis: bacterial diversity in temporomandibular joint synovial fluid in comparison with immunological and clinical findings: Temporomandibular joint (TMJ) involvement in juvenile idiopathic arthritis (JIA) occurs in up to 80% of affected children. The...8hOtoRhinoLaryngology - Alexandros G. SfakianakisAdvanced HNC patients treated with simultaneous integrated boost and volumetric modulated arc therapy Toxicity profile and early clinical outcome for advanced head and neck cancer patients treated with simultaneous integrated boost and volumetric modulated arc therapy: AbstractBackgroundShortening the overall treatment time without increasing acute reactions is one of the major aims in radiotherapy for...8hOtoRhinoLaryngology - Alexandros G. SfakianakisAntimicrobial photodynamic therapy minimizes the deleterious effect of nicotine in female rats with induced periodontitis Antimicrobial photodynamic therapy minimizes the deleterious effect of nicotine in female rats with induced periodontitis: AbstractThe aim of this study was to compare the use of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of experimentally...8hOtoRhinoLaryngology - Alexandros G. SfakianakisIndividual and sex-related differences in pain and relief responsiveness are associated with differences in resting-state functional networks in healthy volunteers Individual and sex-related differences in pain and relief responsiveness are associated with differences in resting-state functional networks in healthy volunteers: AbstractPain processing is associated with neural activity in a number of wide-spread brain regions. Here, we investigated whether functional...8hOtoRhinoLaryngology - Alexandros G. SfakianakisAreas V1 and V2 show microsaccade-related 3-4 Hz covariation in gamma power and frequency Areas V1 and V2 show microsaccade-related 3