Applied Sciences, Vol. 6, Pages 104: Detecting the Presence of High Water-to-Cement Ratio in Concrete Surfaces Using Highly Nonlinear Solitary Waves
We describe a nondestructive evaluation (NDE) method based on the propagation of highly nonlinear solitary waves (HNSWs) to determine the excess of water on the surface of existing concrete structures. HNSWs are induced in a one-dimensional granular chain placed in contact with the concrete to be tested. The chain is part of a built-in transducer designed and assembled to exploit the dynamic interaction between the particles and the concrete. The hypothesis is that the interaction depends on the stiffness of the concrete and influences the time-of-flight of the solitary pulse refl...περισσότερα »
Sensors, Vol. 16, Pages 518: Energy Calibration of a CdTe Photon Counting Spectral Detector with Consideration of its Non-Convergent Behavior
Fast and accurate energy calibration of photon counting spectral detectors (PCSDs) is essential for their biomedical applications to identify and characterize bio-components or contrast agents in tissues. Using the x-ray tube voltage as a reference for energy calibration is known to be an efficient method, but there has been no consideration in the energy calibration of non-convergent behavior of PCSDs. We observed that a single pixel mode (SPM) CdTe PCSD based on Medipix-2 shows some non-convergent behaviors in turning off the detector elements when a high enough threshold is app...περισσότερα »
IJGI, Vol. 5, Pages 49: Requirements on Long-Term Accessibility and Preservation of Research Results with Particular Regard to Their Provenance
Since important national and international funders of research projects require statements on the long-term accessibility of research results, many new solutions appeared to fulfil these demands. The solutions are implemented on various scopes, starting from specific solutions for one research group up to solutions with a national focus (i.e., the RADAR project). While portals for globally standardized research data (e.g., climate data) are available, there is currently no provision for the large amount of data resulting from specialized research in individual research foci, the s... περισσότερα »
Medication review using a Systematic Tool to Reduce Inappropriate Prescribing (STRIP) in adults with an intellectual disability: A pilot study
Publication date: August 2016 *Source:*Research in Developmental Disabilities, Volume 55 Author(s): Rianne J. Zaal, Susan Ebbers, Mirka Borms, Bart de Koning, Erna Mombarg, Piet Ooms, Hans Vollaard, Patricia M.L.A. van den Bemt, Heleen M. Evenhuis A Systematic Tool to Reduce Inappropriate Prescribing (STRIP), which includes the Screening Tool to Alert doctors to Right Treatment (START) and the Screening Tool of Older Peoples' Prescriptions (STOPP), has recently been developed in the Netherlands for older patients with polypharmacy in the general population. Active involvement of the...περισσότερα »
Applied Sciences, Vol. 6, Pages 104: Detecting the Presence of High Water-to-Cement Ratio in Concrete Surfaces Using Highly Nonlinear Solitary Waves
We describe a nondestructive evaluation (NDE) method based on the propagation of highly nonlinear solitary waves (HNSWs) to determine the excess of water on the surface of existing concrete structures. HNSWs are induced in a one-dimensional granular chain placed in contact with the concrete to be tested. The chain is part of a built-in transducer designed and assembled to exploit the dynamic interaction between the particles and the concrete. The hypothesis is that the interaction depends on the stiffness of the concrete and influences the time-of-flight of the solitary pulse refl...περισσότερα »
Sensors, Vol. 16, Pages 518: Energy Calibration of a CdTe Photon Counting Spectral Detector with Consideration of its Non-Convergent Behavior
Fast and accurate energy calibration of photon counting spectral detectors (PCSDs) is essential for their biomedical applications to identify and characterize bio-components or contrast agents in tissues. Using the x-ray tube voltage as a reference for energy calibration is known to be an efficient method, but there has been no consideration in the energy calibration of non-convergent behavior of PCSDs. We observed that a single pixel mode (SPM) CdTe PCSD based on Medipix-2 shows some non-convergent behaviors in turning off the detector elements when a high enough threshold is app...περισσότερα »
IJGI, Vol. 5, Pages 49: Requirements on Long-Term Accessibility and Preservation of Research Results with Particular Regard to Their Provenance
Since important national and international funders of research projects require statements on the long-term accessibility of research results, many new solutions appeared to fulfil these demands. The solutions are implemented on various scopes, starting from specific solutions for one research group up to solutions with a national focus (i.e., the RADAR project). While portals for globally standardized research data (e.g., climate data) are available, there is currently no provision for the large amount of data resulting from specialized research in individual research foci, the s... περισσότερα »
“Darwin’s tubercle” is a term used to describe an atavistic swelling of the posterior helix
Darwin’s Tubercle: Review of a Unique Congenital Anomaly: Abstract Background“Darwin’s tubercle” is a term used to describe an atavistic swelling of the posterior helix that is present in some individuals. Little is known about its prevalence, characteristics, and function. With growing interest in the individuality of external ear patterns and its possible applications to personal identification, more knowledge about this tubercle is warranted. PurposeWe review the history, clinical presentation, and modern-day influences of Darwin’s tubercle. MethodA comprehensive review ... περισσότερα »
Crescendo response to rituximab in oral pemphigus vulgaris
a case with 7-year follow-up: Summary Pemphigus vulgaris (PV) is an autoimmune blistering disease affecting the skin and mucous membranes. Rituximab, a CD20 chimeric monoclonal antibody, has efficacy in PV management. We report a case of severe oral PV that showed a progressive response to repeated courses of rituximab, culminating in a rapid response within 4 weeks following severe relapse 4 years after initial therapy. It demonstrates the progressively shorter time to achieve partial or complete remission following rituximab infusions, combined with minimal adjuvant therapy over ... περισσότερα »
Migraine-tic syndrome
Two further case reports: Background Migraine-tic syndrome was first reported in 2004 in a 44-year-old woman who had concomitant symptoms of both typical trigeminal neuralgia and migraine. We report here two further cases of migraine-tic syndrome and speculate on the relevance of this condition to the pathophysiology of headache. Case reports A 43-year-old woman presented with typical trigeminal neuralgia symptoms that preceded the onset of migraine headache; both headache types responded to treatment with sumatriptan. A 35-year-old woman presented with trigeminal neuralgia that co...περισσότερα »
Cerebellar function and ischemic brain lesions in migraine
patients from the general population: Objective The objective of this article is to obtain detailed quantitative assessment of cerebellar function and structure in unselected migraine patients and controls from the general population. Methods A total of 282 clinically well-defined participants (migraine with aura *n* = 111; migraine without aura *n* = 89; non-migraine controls *n* = 82; age range 43–72; 72% female) from a population-based study were subjected to a range of sensitive and validated cerebellar tests that cover functions of all main parts of the cerebellar cortex, inc... περισσότερα »
Hypoglycaemic encephalopathy
Hypoglycaemic encephalopathy: Description A 49-year-old man with a history of type 1 diabetes self-presented to hospital, with ataxia and memory impairment. Admission blood glucose was 1.9 mmol/L. Using a combination of intravenous and orally administered glucose, the patient became euglycaemic 45 min later. Marked cognitive impairment was noted to persist several days into his admission. An MRI of the brain scan was performed, demonstrating numerous foci of restricted diffusion involving the anterior and posterior territories (figures 1 and 2), including the cortex, subcortical whi... περισσότερα »
Poststernotomy Osteomyelitis Presenting with Severe Sepsis and Rhabdomyolysis
Poststernotomy Osteomyelitis Presenting with Severe Sepsis and Rhabdomyolysis: A 39-year-old male, who recently underwent a composite valve graft of the aortic root and ascending aorta for bicuspid aortic valve and aortic root aneurysm, was hospitalized for severe sepsis, rhabdomyolysis (creatine kinase 29000 U/L), and severe liver dysfunction (AST > 7000 U/L, ALT 4228 U/L, and INR > 10). Cardiac magnetic resonance imaging (MRI) findings were consistent with sternal osteomyelitis with a 1.5 cm abscess at the inferior sternotomy margin, which was contiguous with pericardial thickenin...περισσότερα »
Genome-wide mitochondrial DNA sequence variations and lower expression of OXPHOS genes predict mitochondrial dysfunction in oral cancer tissue
Genome-wide mitochondrial DNA sequence variations and lower expression of OXPHOS genes predict mitochondrial dysfunction in oral cancer tissue: AbstractSeveral studies reported that mtDNA mutations may play important roles in carcinogenesis although the mechanism is not clear yet. Most of the studies compared mtDNA sequences in a tumor with those in normal tissues from different individuals ignoring inter-individual variations. In this study, 271 SNPs, 7 novel SNPs (or SNVs), and 15 somatic mutations were detected in mtDNA of 8 oral cancer tissues with respect to reference (rCRS) a...περισσότερα »
The HLA-DRB1 allele polymorphisms and nasopharyngeal carcinoma
The HLA-DRB1 allele polymorphisms and nasopharyngeal carcinoma: AbstractHuman leukocyte antigen (HLA)-DRB1 has been reported to influence individual’s susceptibility to nasopharyngeal carcinoma (NPC) by many studies in recent years; however, these studies provided controversial results. The meta-analysis was thus conducted here to estimate the relationship between HLA-DRB1 polymorphisms and NPC. After an extensive review of journals from various databases (PubMed, the Web of Science, Embase, China National Knowledge Internet (CNKI), and Wanfang Database), 8 out of 69 case-control s... περισσότερα »
Molecular Profiling in Cutaneous Melanoma
Molecular Profiling in Cutaneous Melanoma: Molecular profiling of malignant tumors is gaining increasing interest in oncology. In recent years, several molecular techniques have been studied in melanoma, with the goal to improve upon the diagnostic and prognostic abilities of currently available clinical and histopathologic parameters. Reliable tests performed early in the diagnosis and management of melanoma could lead to decreased morbidity and mortality by selecting appropriate patients for more-aggressive therapy and sparing those for whom it is not indicated. This article revi...περισσότερα »
Peptide receptor radionuclide therapy for metastatic paragangliomas
Peptide receptor radionuclide therapy for metastatic paragangliomas: AbstractThere is little evidence to direct the management of malignant paragangliomas (mPGL) beyond initial surgical treatment. Peptide receptor radionuclide therapy (PRRT), using somatostatin analogues, is effective in other neuroendocrine tumours, but data on its efficacy in treating mPGL are scarce. We report safety and efficacy outcomes from a case series of five patients with advanced mPGLs treated with 177Lu-DOTATATE PRRT. The mean age of our cohort was 34 years (range 16–47); 4 patients were male with bone ...περισσότερα »
Nonbleeding adenomas
Evidence of systematic false-negative fecal immunochemical test results and their implications for screening effectiveness–A modeling study: [image: cover.gif?v=1&s=6da897ba42f6051a09f07b6e] BACKGROUND If some adenomas do not bleed over several years, they will cause systematic false-negative fecal immunochemical test (FIT) results. The long-term effectiveness of FIT screening has been estimated without accounting for such systematic false-negativity. There are now data with which to evaluate this issue. METHODS The authors developed one microsimulation model (MISCAN [MIcrosimu...περισσότερα »
Neoadjuvant chemotherapy and radical radiotherapy associated with cetuximab for laryngeal cancer in a pancreas and renal recipient
Neoadjuvant chemotherapy and radical radiotherapy associated with cetuximab for laryngeal cancer in a pancreas and renal recipient: [image: image]The oncological treatment for advanced stage head and neck cancer is based on a combination of cisplatin and cetuximab, and radiotherapy. However, very few data are available on this multimodal approach for this type of cancer in pancreas and renal recipients. We report the case of a pancreas and renal recipient being treated with combined chemoradiotherapy for a locally advanced squamous cancer of the larynx. The patient was under treatmen... περισσότερα »
Evaluation of the antineoplastic activity of gallic acid in oral squamous cell carcinoma under hypoxic conditions
Evaluation of the antineoplastic activity of gallic acid in oral squamous cell carcinoma under hypoxic conditions: The purpose of the current study was to develop and test a theoretical model that could explain the mechanism of action of gallic acid (GA) in the oral squamous cell carcinoma context for the first time. The theoretical model was developed using bioinformatics and interaction network analysis to evaluate the effect of GA on oral squamous cell carcinoma. In a second step to confirm theoretical results, migration, invasion, proliferation, and gene expression (Col1A1, E-ca... περισσότερα »
Whole blood zinc and copper levels in children with autism spectrum disorder
Evaluation of whole blood zinc and copper levels in children with autism spectrum disorder: AbstractZinc (Zn) and copper (Cu) are important trace elements for cognitive development and normal neurological functioning. Autism spectrum disorder (ASD) is a common neurological disorder, which has previously been associated with the levels of some trace elements in the blood. However, clinical data regarding the potential implication of Zn and Cu in patients with ASD are still insufficient. Therefore, the aim of the present study was to investigate the whole blood levels of Zn and Cu in... περισσότερα »
Outcomes of patients with loco-regionally recurrent or new primary squamous cell carcinomas of the head and neck treated with curative intent reirradiation
at Mayo Clinic: Abstract BackgroundWe reviewed outcomes of patients with loco-regionally recurrent (LRR) or new primary (NP) squamous cell carcinoma of the head and neck (SCCHN) treated at our institution with reirradiation (RRT). MethodsPatients received definitive RRT (DRRT) or post-operative RRT following salvage surgery (PRRT) from 2003 to 2011. Measured survival outcomes included loco-regional relapse free survival (LRFS) and overall survival (OS). ResultsAmong 81 patients (PRRT, 42; DRRT, 39), median PRRT and DRRT doses were 60 Gy (12–70 Gy) and 69.6 Gy (48–76.8 Gy)....περισσότερα »
High body mass index and cancer risk
—a Mendelian randomisation study: AbstractHigh body mass index (BMI) has been associated with increased risk of some cancer. Whether these reflect causal associations is unknown. We examined this issue. Using a Mendelian randomisation approach, we studied 108,812 individuals from the general population. During a median of 4.7 years of follow-up (range 0–37), 8002 developed non-skin cancer, 3347 non-melanoma skin cancer, 1396 lung cancer, 637 other smoking related cancers, 1203 colon cancer, 159 kidney cancer, 1402 breast cancer, 1062 prostate cancer, and 2804 other cancers. Partici... περισσότερα »
Nodnett - The New Digital Public Safety Communication System in Norway
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 23 δευτερόλεπτα
Simens got the job, lost it over coruption. Finaly, after years of talk, it is a TETRA system covering Norway. Hope it is upp for the job. ExEMTNor from EMS via xlomafota13 on Inoreader http://ift.tt/1NjCTa0 via IFTTT
Nodnett - The New Digital Public Safety Communication System in Norway
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 23 δευτερόλεπτα
Simens got the job, lost it over coruption. Finaly, after years of talk, it is a TETRA system covering Norway. Hope it is upp for the job. ExEMTNor from EMS via xlomafota13 on Inoreader http://ift.tt/1NjCTa0 via IFTTT
Nodnett - The New Digital Public Safety Communication System in Norway
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 23 δευτερόλεπτα
Simens got the job, lost it over coruption. Finaly, after years of talk, it is a TETRA system covering Norway. Hope it is upp for the job. ExEMTNor from EMS via xlomafota13 on Inoreader http://ift.tt/1NjCTa0 via IFTTT
Degree of anxiety in food allergic children
in a tertiary care center via ScienceDirect Publication: Annals of Allergy, Asthma & Immunology Publication date: Available online 8 April 2016 Source:Annals of Allergy, Asthma & Immunology Author(s): Lidija Petrovic-Dovat, Tracy Fausnight, Amanda M. White, Timothy Zeiger, Pevitr S. Bansal, Nidhi Garg, Jitendra Annapareddy, Sarah Iriana, Marcia J. Slattery, Roger E. Meyer, Edward O. Bixler… Continue reading Degree of anxiety in food allergic children
Predictive values of egg specific IgE by two commonly used assay systems for the diagnosis of egg allergy in young children: a prospective multicenter study
: a prospective multicenter study: Abstract Background Specific IgE (sIgE) is often used to predict oral food challenge (OFC) outcomes in food allergy, but interpretation of the results may vary depending on the assay method employed and the patient population tested. The aim of this study was to use two commercial assay systems to determine… Continue reading Predictive values of egg specific IgE by two commonly used assay systems for the diagnosis of egg allergy in young children: a prospective multicenter study
Respiratory Syncytial Virus Infection Activates IL-13-Producing Group 2 Innate Lymphoid Cells
via Thymic Stromal Lymphopoietin via Allergy and Clinical Immunology Publication date: Available online 9 April 2016 Source:Journal of Allergy and Clinical Immunology Author(s): Matthew T. Stier, Melissa H. Bloodworth, Shinji Toki, Dawn C. Newcomb, Kasia Goleniewska, Kelli L. Boyd, Marc Quitalig, Anne L. Hotard, Martin L. Moore, Tina V. Hartert, Baohua Zhou, Andrew N. McKenzie,… Continue reading Respiratory Syncytial Virus Infection Activates IL-13-Producing Group 2 Innate Lymphoid Cells
Can we prevent food allergy and eczema in our baby?.
Doctor, can we prevent food allergy and eczema in our baby?.: Purpose of review: The purpose is to review evidence from recent clinical trials that focus on early life interventions to prevent the onset of eczema and food allergy. Recent findings: There is evidence that skin barrier defects may be a risk factor for the… Continue reading Can we prevent food allergy and eczema in our baby?.
Allergen Immunotherapy: No Evidence of Infectious Risk
Allergen Immunotherapy: No Evidence of Infectious Risk via Allergy and Clinical Immunology Publication date: Available online 9 April 2016 Source:Journal of Allergy and Clinical Immunology Author(s): Diana S. Balekian, Aleena Banerji, Kimberly Blumenthal, Carlos A. Camargo, Aidan A. Long Although allergen immunotherapy (AIT) is thought to be a safe treatment for allergic rhinitis, only one… Continue reading Allergen Immunotherapy: No Evidence of Infectious Risk
A five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors
Phase I clinical trial of via Clinical Immunology Publication date: Available online 9 April 2016 Source:Clinical Immunology Author(s): Mutsunori Murahashi, Yasuki Hijikata, Kazunari Yamada, Yoshihiro Tanaka, Junji Kishimoto, Hiroyuki Inoue, Tomotoshi Marumoto, Atsushi Takahashi, Toshihiko Okazaki, Kazuyoshi Takeda, Masakazu Hirakawa, Hiroshi Fujii, Shinji Okano, Masaru Morita, Eishi Baba, Kazuhiro Mizumoto, Yoshihiko Maehara, Masao Tanaka, Koichi… Continue reading A five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors
Lipofilling may induce nerve regeneration after previous traumatic injury
a clinical case with remarkable outcome: Abstract Despite the fast amount of techniques, which promote nerve regeneration, the outcomes of high ulnar nerve injuries are still poor. This case report illuminates the usability of lipofilling in peripheral nerve regeneration. In the case described, we encountered a successful regeneration with return of sensibility and motor function.… Continue reading Lipofilling may induce nerve regeneration after previous traumatic injury
Ganglion and Synovial Cyst of the Temporomandibular Joint
A Case Report and Literature Review: Summary: Ganglion and synovial cysts of the temporomandibular joint (TMJ) are rare. Although histopathological findings differ, clinical presentation is comparable. This study adds a case report of a ganglion of the TMJ to existing literature and a review of all available case reports on ganglion and synovial cysts of… Continue reading Ganglion and Synovial Cyst of the Temporomandibular Joint
Remote ischemic perconditioning attenuates acute inflammation of experimental musculocutaneous flaps following ischemia-reperfusion injury
Remote ischemic perconditioning attenuates acute inflammation of experimental musculocutaneous flaps following ischemia-reperfusion injury: Background In free flap reconstruction and replantation surgery, prolonged ischemia time may lead to flap or replantation failure. The aim of the study was to investigate the effects of hypothermic flap ischemia or remote ischemic perconditioning (RIPER) during normothermic ischemia on acute… Continue reading Remote ischemic perconditioning attenuates acute inflammation of experimental musculocutaneous flaps following ischemia-reperfusion injury
The Versatile Modiolus Perforator Flap
The Versatile Modiolus Perforator Flap: Background: Perforator flaps are well established, and their usefulness as freestyle island flaps is recognized. The whereabouts of vascular perforators and classification of perforator flaps in the face are a debated subject, despite several anatomical studies showing similar consistency. In our experience using freestyle facial perforator flaps, we have located… Continue reading The Versatile Modiolus Perforator Flap
Cricoid and left bronchial diameter in the pediatric population
Cricoid and left bronchial diameter in the pediatric population: Summary Background Lung isolation in the pediatric population can be problematic. The diameter and length of the right and left mainstem bronchi are not well described in young children. Information regarding these measurements may help determine the appropriate size of endotracheal tubes for endobronchial intubation as well as the development of lung isolation devices for the pediatric population. The present study is based on computed tomography (CT) measurements to evaluate airway dimensions. The goal of this study ...περισσότερα »
Noninvasive positive pressure ventilation (NPPV) using a helmet
Work of breathing using different interfaces in spontaneous positive pressure ventilation: helmet, face-mask, and endotracheal tube: Abstract PurposeNoninvasive positive pressure ventilation (NPPV) using a helmet is expected to cause inspiratory trigger delay due to the large collapsible and compliant chamber. We compared the work of breathing (WOB) of NPPV using a helmet or a full face-mask with that of invasive ventilation by tracheal intubation. MethodsWe used a lung model capable of simulating spontaneous breathing (LUNGOO; Air Water Inc., Japan). LUNGOO was set at complian...περισσότερα »
Work of breathing using different interfaces in spontaneous positive pressure ventilation
: helmet, face-mask, and endotracheal tube: Abstract PurposeNoninvasive positive pressure ventilation (NPPV) using a helmet is expected to cause inspiratory trigger delay due to the large collapsible and compliant chamber. We compared the work of breathing (WOB) of NPPV using a helmet or a full face-mask with that of invasive ventilation by tracheal intubation. MethodsWe used a lung model capable of simulating spontaneous breathing (LUNGOO; Air Water Inc., Japan). LUNGOO was set at compliance (*C* ) = 50 mL/cmH2O and resistance (*R*) = 5 cmH2O/L/s for normal lung simulation, *C...περισσότερα »
Eosinophilic Esophagitis : TGFβ1-Induced PAI-1 Contributes to a Pro-Fibrotic Network
TGFβ1-Induced PAI-1 Contributes to a Pro-Fibrotic Network in Eosinophilic Esophagitis via Allergy and Clinical Immunology Publication date: Available online 8 April 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Renee Rawson, Tom Yang, Robert O. Newbury, Melissa Aquino, Ashmi Doshi, Braxton Bell, David H. Broide, Ranjan Dohil, Richard Kurten, Seema S. Aceves BackgroundEosinophilic esophagitis is an allergic disease of increasing worldwide incidence. Complications are due to tissue remodeling and involve transforming growth factor-β1 (TGFβ1) mediated fibrosis. Plasm... περισσότερα »
Degree of anxiety in food allergic children
in a tertiary care center via ScienceDirect Publication: Annals of Allergy, Asthma & Immunology Publication date: Available online 8 April 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Lidija Petrovic-Dovat, Tracy Fausnight, Amanda M. White, Timothy Zeiger, Pevitr S. Bansal, Nidhi Garg, Jitendra Annapareddy, Sarah Iriana, Marcia J. Slattery, Roger E. Meyer, Edward O. Bixler BackgroundThe link between internalizing psychiatric disorders, such as anxiety and depression, and allergic diseases has attracted a high level of interest from psychiatrists and immunologists. Re... περισσότερα »
Predictive values of egg specific IgE by two commonly used assay systems for the diagnosis of egg allergy in young children: a prospective multicenter study
: a prospective multicenter study: Abstract Background Specific IgE (sIgE) is often used to predict oral food challenge (OFC) outcomes in food allergy, but interpretation of the results may vary depending on the assay method employed and the patient population tested. The aim of this study was to use two commercial assay systems to determine egg sIgE values predictive of allergy within the most common populations treated at pediatric clinics. Methods In a multicenter prospective study, 433 children with suspected or confirmed egg allergy underwent oral challenge (OFC) using cooked e... περισσότερα »
Respiratory Syncytial Virus Infection Activates IL-13-Producing Group 2 Innate Lymphoid Cells
via Thymic Stromal Lymphopoietin via Allergy and Clinical Immunology Publication date: Available online 9 April 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Matthew T. Stier, Melissa H. Bloodworth, Shinji Toki, Dawn C. Newcomb, Kasia Goleniewska, Kelli L. Boyd, Marc Quitalig, Anne L. Hotard, Martin L. Moore, Tina V. Hartert, Baohua Zhou, Andrew N. McKenzie, R. Stokes Peebles BackgroundRespiratory syncytial virus (RSV) is a major healthcare burden with a particularly high worldwide morbidity and mortality rate among infants. Data suggest that severe RSV-associate... περισσότερα »
Can we prevent food allergy and eczema in our baby?.
Doctor, can we prevent food allergy and eczema in our baby?.: Purpose of review: The purpose is to review evidence from recent clinical trials that focus on early life interventions to prevent the onset of eczema and food allergy. Recent findings: There is evidence that skin barrier defects may be a risk factor for the development of eczema and may increase the risk of early onset food sensitization and allergy. The measurement of transepidermal water loss as a marker of skin barrier defect may be a simple, noninvasive measurement that may predict who is at risk of eczema, however, ... περισσότερα »
Allergen Immunotherapy: No Evidence of Infectious Risk
Allergen Immunotherapy: No Evidence of Infectious Risk via Allergy and Clinical Immunology Publication date: Available online 9 April 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Diana S. Balekian, Aleena Banerji, Kimberly Blumenthal, Carlos A. Camargo, Aidan A. Long Although allergen immunotherapy (AIT) is thought to be a safe treatment for allergic rhinitis, only one prior study reported no risk of infection due to AIT. We examined >130,000 AIT injections and found no infections associated with injections.
A five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors
Phase I clinical trial of via Clinical Immunology Publication date: Available online 9 April 2016 *Source:*Clinical Immunology Author(s): Mutsunori Murahashi, Yasuki Hijikata, Kazunari Yamada, Yoshihiro Tanaka, Junji Kishimoto, Hiroyuki Inoue, Tomotoshi Marumoto, Atsushi Takahashi, Toshihiko Okazaki, Kazuyoshi Takeda, Masakazu Hirakawa, Hiroshi Fujii, Shinji Okano, Masaru Morita, Eishi Baba, Kazuhiro Mizumoto, Yoshihiko Maehara, Masao Tanaka, Koichi Akashi, Yoichi Nakanishi, Koji Yoshida, Takuya Tsunoda, Kazuo Tamura, Yusuke Nakamura, Kenzaburo Tani We designed a phase I trial to inve... περισσότερα »
Lipofilling may induce nerve regeneration after previous traumatic injury
a clinical case with remarkable outcome: AbstractDespite the fast amount of techniques, which promote nerve regeneration, the outcomes of high ulnar nerve injuries are still poor. This case report illuminates the usability of lipofilling in peripheral nerve regeneration. In the case described, we encountered a successful regeneration with return of sensibility and motor function. We believe that the rationale for this technique is the presence of adipose-derived stem cells (ADSCs). We speculate that this improvement depends on tissue regeneration induced by these ADSCs. Level of E... περισσότερα »
Ganglion and Synovial Cyst of the Temporomandibular Joint
A Case Report and Literature Review: Summary: Ganglion and synovial cysts of the temporomandibular joint (TMJ) are rare. Although histopathological findings differ, clinical presentation is comparable. This study adds a case report of a ganglion of the TMJ to existing literature and a review of all available case reports on ganglion and synovial cysts of the TMJ. Including our own case report, we reviewed 49 cases of ganglion and synovial cysts of the TMJ. They occurred in a female:male ratio of 3:1, at an median age of 46 years (range, 11–64 years). Patients mainly presented with ... περισσότερα »
Remote ischemic perconditioning attenuates acute inflammation of experimental musculocutaneous flaps following ischemia-reperfusion injury
Remote ischemic perconditioning attenuates acute inflammation of experimental musculocutaneous flaps following ischemia-reperfusion injury: Background In free flap reconstruction and replantation surgery, prolonged ischemia time may lead to flap or replantation failure. The aim of the study was to investigate the effects of hypothermic flap ischemia or remote ischemic perconditioning (RIPER) during normothermic ischemia on acute inflammation of musculocutaneous flaps subjected to ischemia-reperfusion injury. *Materials and methods*: In 24 pigs, a musculocutaneous latissimus dorsi fl...περισσότερα »
The Versatile Modiolus Perforator Flap
The Versatile Modiolus Perforator Flap: [image: image]Background: Perforator flaps are well established, and their usefulness as freestyle island flaps is recognized. The whereabouts of vascular perforators and classification of perforator flaps in the face are a debated subject, despite several anatomical studies showing similar consistency. In our experience using freestyle facial perforator flaps, we have located areas where perforators are consistently found. This study is focused on a particular perforator lateral to the angle of the mouth; the modiolus and the versatile modi... περισσότερα »
Red and white oral lesions
Correlation of serum ANA and direct immunofluorescence studies in elderly Thai patients with red and white oral lesions: [image: cover.gif?v=1&s=a0ff55faa388bf623a351a74] Objectives This study investigated the presence of serum antinuclear antibodies (ANA) profile and direct immunofluorescence (DIF) evaluation in elderly Thai patients with red and white oral lesions. Materials and Methods Thirty-two patients with red and white oral lesions were divided into two groups: group I consisted of 10 cases not taking medications, while group II consisted of 12 cases taking medications, a... περισσότερα »
The mobile tongue.....Adenoid cystic carcinoma
Adenoid cystic carcinoma: A rare late presentation of the mobile tongue via ScienceDirect Publication: Journal of Oral Biology and Craniofacial Research Publication date: Available online 7 April 2016 *Source:*Journal of Oral Biology and Craniofacial Research Author(s): Sanjay Kumar, Padmanidhi Agarwal, V. Nimmi Adenoid cystic carcinoma (ACC) is an infrequent malignant neoplasm of the salivary glands. We present a case of a 70-year-old male patient with a swelling over the dorsal and ventral surface of anterior two third of the tongue which was causing him difficulty in mastication sinc...περισσότερα »
Spontaneous herniation of the condylar head into the external auditory canal (EAC) through the foramen of Huschke
Temporoparietal fascia flap and total temporomandibular joint replacement for the management of patent foramen of Huschke by M.C. Shapiro, T. Osborn via Oral & Maxillofacial Surgery Abstract Spontaneous herniation of the condylar head into the external auditory canal (EAC) through the foramen of Huschke is extremely rare, with approximately 30 cases reported in the international literature. The typical presentation is a constellation of non-specific symptoms including otalgia, temporomandibular joint (TMJ) pain, malocclusion, otorrhea, tinnitus while chewing, and hearing loss. Clinica... περισσότερα »
The insular cortex (IC), the integration of olfactory and gustatory chemosignals
Integration of olfactory and gustatory chemosignals in the insular cortex via ScienceDirect Publication: Journal of Oral Biosciences Publication date: Available online 8 April 2016 *Source:*Journal of Oral Biosciences Author(s): Naoko Mizoguchi, Masayuki Kobayashi, Kazuyo Muramoto BackgroundFlavor is an integrative sensation comprised of taste, odor, and mouthfeel. The interaction between olfactory cues and taste is particularly important for flavor formation. Because odor information is conveyed to the insular cortex (IC), the integration of olfactory and gustatory chemosignals may be ...περισσότερα »
Aberrant temporal branch of facial nerve
Aberrant temporal branch of facial nerve via British Journal of Oral and Maxillofacial Surgery Publication date: Available online 8 April 2016 *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Tun Wildan, Nasser Nasser There is a high risk of injury to the temporal branch of the facial nerve during operations on the head and neck because of the complexity of its course. We report an aberrant branch that arose from the main trunk before bifurcation into the temporofacial and cervicofacial divisions. It had no anastomosis with other branches, and damage could have caus...περισσότερα »
Managing arteriovenous malformations of the head and neck
Experiences in via British Journal of Oral and Maxillofacial Surgery Publication date: Available online 8 April 2016 *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Kevin McMillan, Louise Dunphy, Hiroshi Nishikawa, Andrew Monaghan Arteriovenous malformations of the head and neck are difficult to treat and require a multidisciplinary approach. Interventional radiology can now be used to downgrade previously inoperable lesions to enable ablation, and the use of Onyx® (Covidien, Irvine, CA, USA), which has revolutionised their management by allowing precise obliterat...περισσότερα »
Sublingual lymphangioma that presented as a plunging ranula in a baby boy
Sublingual lymphangioma that presented as a plunging ranula in a baby boy via British Journal of Oral and Maxillofacial Surgery Publication date: Available online 8 April 2016 *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Amal Faisal Al-Abdulla, Shilpa Prabhu, Mohammed A. Al-Muharraqi, Abdulla Hassan Darwish, Veena Nagaraj Figures and tables 1. [image: Newborn baby with cystic lesion in the floor of the mouth.] 2. [image: Thin vascular channels lined by flat endothelial cells (black arrow) with ...]
Effect of nasal high-flow oxygen therapy on the swallowing reflex
: an in vivo volunteer study: Abstract ObjectiveThe advantages of nasal high-flow oxygen therapy (NHF) include not only allowing talking, but also eating and drinking, during the therapy. However, the effect of NHF on the swallowing reflex remains unclear. In the present study, we aimed to assess the effects of NHF on the swallowing reflex. MethodsNine healthy adult Japanese male volunteers with no history of dysphagia or diseases that may cause dysphagia, such as stroke or Parkinson’s disease, were evaluated. Participants received one of four levels of NHF intervention (0 (co... περισσότερα »
The facial flat wart (verruca plana)
Off-label photodynamic therapy for recalcitrant facial flat warts using topical 5-aminolevulinic acid: AbstractThe facial flat wart (verruca plana) is one of the most common reasons for dermatology and primary care visits. Although there are many therapeutic modalities, no single therapy has been proven to be completely curative. Case reports and uncontrolled studies suggested that photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA) can effectively treat recalcitrant facial flat warts. A total of 12 patients with recalcitrant facial flat warts were enrolled in the s... περισσότερα »
Off-label photodynamic therapy for recalcitrant facial flat warts using topical 5-aminolevulinic acid
Off-label photodynamic therapy for recalcitrant facial flat warts using topical 5-aminolevulinic acid: AbstractThe facial flat wart (verruca plana) is one of the most common reasons for dermatology and primary care visits. Although there are many therapeutic modalities, no single therapy has been proven to be completely curative. Case reports and uncontrolled studies suggested that photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA) can effectively treat recalcitrant facial flat warts. A total of 12 patients with recalcitrant facial flat warts were enrolled in the s... περισσότερα »
Sentence Repetition Accuracy
in Adults With Developmental Language Impairment: Interactions of Participant Capacities and Sentence Structures: Purpose We asked whether sentence repetition accuracy could be explained by interactions of participant processing limitations with the structures of the sentences. We also tested a prediction of the procedural deficit hypothesis (Ullman & Pierpont, 2005) that adjuncts are more difficult than arguments for individuals with developmental language impairment (DLI). Method Forty-four young adults participated, 21 with DLI. The sentence repetition task varied sentence len... περισσότερα »
Dysarthria in Adults With Cerebral Palsy
: Clinical Presentation and Impacts on Communication: Purpose Although dysarthria affects the large majority of individuals with cerebral palsy (CP) and can substantially complicate everyday communication, previous research has provided an incomplete picture of its clinical features. We aimed to comprehensively describe characteristics of dysarthria in adults with CP and to elucidate the impact of dysarthric symptoms on parameters relevant for communication. Method Forty-two adults with CP underwent speech assessment by means of standardized auditory rating scales. Listening exper... περισσότερα »
Patient Complexity Charge Matrix for Audiology Services
: A New Perspective on Unbundling: Semin Hear 2016; 37: 148-160 DOI: 10.1055/s-0036-1579703 Traditional approaches to unbundling hearing aid services often take existing bundled charges and then separate the charges across all potential services associated with dispensing the devices. However, this method results in every patient being charged the same amount even though the complexity of the service varies across patients. We describe a model of charging for hearing aid services that takes into account three elements associated with patient services (i.e., assessing hearing status...περισσότερα »
Interventional Audiology
: Broadening the Scope of Practice to Meet the Changing Demands of the New Consumer: Semin Hear 2016; 37: 120-136 DOI: 10.1055/s-0036-1579705 Given the growth in the aging population, low hearing uptake rates and the emerging science indicating that age-related hearing loss has long term consequences to health and wellness, an interventional audiology strategy is needed. This paper will define interventional audiology and offer guidance on bringing an interventional audiology to life in clinical practice. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.... περισσότερα »
Application of the Consumer Decision-Making Model to Hearing Aid Adoption in First-Time Users
Application of the Consumer Decision-Making Model to Hearing Aid Adoption in First-Time Users: Semin Hear 2016; 37: 103-119 DOI: 10.1055/s-0036-1579706 Since 1980, hearing aid adoption rates have remained essentially the same, increasing at a rate equal to the organic growth of the population. Researchers have used theoretical models from psychology and sociology to determine those factors or constructs that lead to the adoption of hearing aids by first-time impaired listeners entering the market. In this article, a theoretical model, the Consumer Decision-Making Model (CDM), premi... περισσότερα »
How to Implement Itemization in an Audiology Practice
How to Implement Itemization in an Audiology Practice: Semin Hear 2016; 37: 137-147 DOI: 10.1055/s-0036-1579704 The hearing aid delivery landscape has dramatically changed over the past several years, with a commercial payer, the Internet, and big box stores dispensing hearing aids directly to patients. The audiology community needs to modify the bundled billing model. This session will describe how to optimize the services you provide to current and new patients and change the hearing aid delivery and hearing aid pricing model to remain competitive with these new market trends. Th...περισσότερα »
Informational Masking
in Normal-Hearing and Hearing-Impaired Listeners Measured in a Nonspeech Pattern Identification Task: Individuals with sensorineural hearing loss (SNHL) often experience more difficulty with listening in multisource environments than do normal-hearing (NH) listeners. While the peripheral effects of sensorineural hearing loss certainly contribute to this difficulty, differences in central processing of auditory information may also contribute. To explore this issue, it is important to account for peripheral differences between NH and these hearing-impaired (HI) listeners so that c... περισσότερα »
Associations Between Money and Death
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The finding that income predicts mortality has a long history. Nineteenth-century studies include Villermé on Paris, France, in 1817, Engels on Manchester, England, in 1850, and Virchow on Upper Silesia in 1847 through 1848. Modern analyses include the Whitehall study of British civil servants, whose status was measured by income, as well as similar findings […]
Improving Opportunity, Population Health, and Well-being Collectively
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Life expectancy is lower and disease morbidity is higher in the United States than in other high-income countries. This situation, decades old, is not for lack of skilled medical care; the United States has among the world’s best hospitals and technology. Nor is spending on health care inadequate; per capita health expenditures in the United […]
Income, Longevity, and Community Health
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
“Protecting health, saving lives—millions at a time” is the motto of the Johns Hopkins Bloomberg School of Public Health. Although not the principal motivation for or lesson from the assessment by Chetty and colleagues published in JAMA, encouraging prospects for community health strategies are suggested by the findings in this article on income and life […]
Association Between Income and Life Expectancy in the United States
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
This study uses deidentified US tax records to estimate race- and ethnicity-adjusted life expectancy at 40 years of age by household income percentile, sex, and geographic area, and to evaluate factors associated with differences in life expectancy. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UUmZuF via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 […]
Modern technologies for improving cleaning and disinfection of environmental surfaces in hospitals
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Experts agree that careful cleaning and disinfection of environmental surfaces are essential elements of effective infection prevention programs. However, traditional manual cleaning and disinfection practices in hospitals are often suboptimal. This is often due in part to a variety of personnel issues that many Environmental Services departments encounter. Failure to follow manufacturer’s recommendations for […]
A single natural nucleotide mutation alters bacterial pathogen host-tropism
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Nature genetics from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S05hQE via IFTTT
Assessing Cell and Organ Senescence Biomarkers
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Circulation research from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1N3f7ED via IFTTT
Fighting disease from the chromosome end
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Epigenomics from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S05gMG via IFTTT
Malaria morbidity and mortality in Ebola-affected countries caused by decreased health-care capacity, and the potential effect of mitigation strategies: a modelling analysis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The Lancet. Infectious diseases from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1N3f7Eo via IFTTT
Assessing the epidemiological impact of Wolbachia deployment for dengue control
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The Lancet. Infectious diseases from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S05eo0 via IFTTT
Unique geometry of sister kinetochores in human oocytes during meiosis I may explain maternal age-associated increases in chromosomal abnormalities
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Biology Open from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1N3f8Z0 via IFTTT
Conditioned respiratory threat in the subdivisions of the human periaqueductal gray
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
eLife from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S05gw5 via IFTTT
The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Nature from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1N3f8Iy via IFTTT
L-type calcium channels as drug targets in CNS disorders
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Channels from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S05dQS via IFTTT
A novel locus of resistance to severe malaria in a region of ancient balancing selection
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Nature from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1N3f77j via IFTTT
Sensors, Vol. 16, Pages 507: A Two-Phase Space Resection Model for Accurate Topographic Reconstruction from Lunar Imagery with PushbroomScanners
Exterior orientation parameters' (EOP) estimation using space resection plays an important role in topographic reconstruction for push broom scanners. However, existing models of space resection are highly sensitive to errors in data. Unfortunately, for lunar imagery, the altitude data at the ground control points (GCPs) for space resection are error-prone. Thus, existing models fail to produce reliable EOPs. Motivated by a finding that for push broom scanners, angular rotations of EOPs can be estimated independent of the altitude data and only involving the geographic data at the... περισσότερα »
TWiV 384: Agent 003, a view to a fish kill
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1UU9NG1 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
National G6PD neonatal screening program in Gaza Strip of Palestine: rationale, challenges and recommendations
Abstract Congenital genetic disorders affecting neonates or young children can have serious clinical consequences if undiagnosed and left untreated. Early detection and an accurate diagnosis are, therefore, of major importance for preventing negative patient outcomes. Even though the occurrence of each specific metabolic disorder may be rare, their collective impact of preventable complications may be… Continue reading National G6PD neonatal screening program in Gaza Strip of Palestine: rationale, challenges and recommendations
National G6PD neonatal screening program in Gaza Strip of Palestine: rationale, challenges and recommendations
Abstract Congenital genetic disorders affecting neonates or young children can have serious clinical consequences if undiagnosed and left untreated. Early detection and an accurate diagnosis are, therefore, of major importance for preventing negative patient outcomes. Even though the occurrence of each specific metabolic disorder may be rare, their collective impact of preventable complications may be… Continue reading National G6PD neonatal screening program in Gaza Strip of Palestine: rationale, challenges and recommendations
Biopsy-Proven IgG4-Related Lung Disease
Gain a better understanding of lung involvement in immunoglobulin G4-related disease. BMC Pulmonary Medicine from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1oPpv7b via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/23nGlgz via IFTTT
Dermatomyositis As a Prodromal Sign of Lung Adenocarcinoma
This case report highlights the importance of a thorough search for underlying malignancy in patients with dermatomyositis. Journal of Medical Case Reports from Uncategorized via xlomafota13 on Inoreader http://ift.tt/23nG0dO via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1YoupnU via IFTTT
National G6PD neonatal screening program in Gaza Strip of Palestine: rationale, challenges and recommendations
Abstract Congenital genetic disorders affecting neonates or young children can have serious clinical consequences if undiagnosed and left untreated. Early detection and an accurate diagnosis are, therefore, of major importance for preventing negative patient outcomes. Even though the occurrence of each specific metabolic disorder may be rare, their collective impact of preventable complications may be… Continue reading National G6PD neonatal screening program in Gaza Strip of Palestine: rationale, challenges and recommendations
New Brain Disorder Identified in Zika-Infected Patients (FREE)
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
By Kelly Young Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH The Zika virus may be associated with acute disseminated encephalomyelitis (ADEM), an inflammation of the brain and spinal cord, according to a small study being … from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1qIqp7w via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via […]
Your NEJM Group Today: Chemo-Induced Nausea & Vomiting, Pedometer Exercise Program, Ohio IM Opportunities (FREE)
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
By the Editors NEJM Group offers so many valuable resources for practicing clinicians. Here’s what we chose for you today:NEJM Clinical Practice Center: Review: One … from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1qIqpnS via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1qIyEAB via IFTTT
FDA Loosens Restrictions on Metformin Use in Patients with Mild-to-Moderate Kidney Dysfunction (FREE)
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
By Kelly Young Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH Metformin may be safely used in all patients with mild renal impairment and in some with moderate impairment, according to new label changes from the FDA. Previously, the label … from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1NjuDH4 via IFTTT from #Med Blogs […]
From the Blogs: Costs of Being a Doctor, When Providers Need Care (FREE)
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
By the Editors Take a look at what the NEJM Journal Watch bloggers are talking about right now: Insights on Residency Training: Dr. Ahmad Yousaf … from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1NjuAuU via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1qIyGZh via IFTTT
First Transplanted Uterus in U.S. Removed Because of Yeast Infection (FREE)
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
By the Editors A yeast infection necessitated the removal of the first transplanted uterus in the U.S., the New York … from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1qIqoR1 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1qi6Ou5 via IFTTT
Characterization of a multiprotein complex involved in excitation-transcription coupling of skeletal muscle
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Background: Electrical activity regulates the expression of skeletal muscle genes by a process known as «excitation-transcription» (E-T) coupling. We have demonstrated that release of adenosine 5′-triphosphate (ATP) during depolarization activates membrane P2X/P2Y receptors, being the fundamental mediators between electrical stimulation, slow intracellular calcium transients, and gene expression. We propose that this signaling pathway would require […]
Atypical antipsychotic medications and hyponatremia in older adults: a population-based cohort study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Background: A number of case reports have suggested a possible association between atypical antipsychotic medications and hyponatremia. Currently, there are no reliable estimates of hyponatremia risk from atypical antipsychotic drugs.ObjectiveThe objective of this study was to examine the 30-day risk of hospitalization with hyponatremia in older adults dispensed an atypical antipsychotic drug relative to no […]
Endothelial, platelet, and macrophage microparticle levels do not change acutely following transcatheter aortic valve replacement
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Background: Patients with severe aortic stenosis have increased levels of prothrombotic and proinflammatory microparticles (MP), and MPs actively regulate pathological processes that lead to atherothrombotic cardiovascular events. Shear stress is a validated stimulus of MP production, and abnormal shear stress in aortic stenosis increases MP release in ex-vivo studies. We hypothesized that in patients with […]
Role of sclerostin in the pathogenesis of chronic kidney disease-mineral bone disorder
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Sclerostin is a 190-amino-acid glycoprotein that is mainly secreted by osteocytes, and it decreases bone formation by inhibiting the terminal differentiation of osteoblasts and promoting their apoptosis. Sclerostin blocks the Wnt signaling pathway in osteoblasts by binding to low-density lipoprotein receptor-related protein 5/6 (LRP-5/6) receptors. We reviewed the literature detailing the role of sclerostin in […]
TWiV 384: Agent 003, a view to a fish kill
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1UU9NG1 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/23nBADO via IFTTT
National G6PD neonatal screening program in Gaza Strip of Palestine: rationale, challenges and recommendations
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Abstract Congenital genetic disorders affecting neonates or young children can have serious clinical consequences if undiagnosed and left untreated. Early detection and an accurate diagnosis are, therefore, of major importance for preventing negative patient outcomes. Even though the occurrence of each specific metabolic disorder may be rare, their collective impact of preventable complications may be of considerable importance to the public health. Our previous studies showed that G6PD deficiency is a problem of public health importance that has been shown to be a predominant caus...περισσότερα »
