Protective effects of the notoginsenoside R1 on acute lung injury by regulating the miR-128-2-5p/Tollip signaling pathway in rats with severe acute pancreatitis

alwin shared this article with you from Inoreader Protective effects of the notoginsenoside R1 on acute lung injury by regulating the miR-128-2-5p/Tollip signaling pathway in rats with severe acute pancreatitis Via Innate Immunity In this study, we explored the pulmonary protective effect and the underlying mechanism of the NG-R1 on rats with ALI induced by severe acute pancreatitis (SAP). MiR-128-2-5p, ERK1, Tollip, HMGB1, TLR4, IκB, and NF-κB mRNA expression levels were measured using real-time qPCR, and TLR4, Tollip, HMGB1, IRAK1, MyD88, ERK1, NF-κB65, and P-IκB-α protein expression levels using Western blot. The NF-κB and the TLR4 activities were determined using immunohistochemistry, and TNF-α, IL-6, IL-1β, and ICAM-1 levels in the bronchoalveolar lavage fluid (BALF) using ELISA. Lung histopathological changes were observed in each group. NG-R1 treatment reduced miR-128-2-5p expression in the lung tissue, increased Tollip expression, inhibited HMGB1, TLR4, TRAF6, IRAK1, MyD88, NF-κB65, and p-IκB-α ex... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Do the new protocols of prf centrifugation allow better control of postoperative complications and healing after surgery of impacted lower third molar? a systematic review and meta-analysis

alwin shared this article with you from Inoreader Do the new protocols of prf centrifugation allow better control of postoperative complications and healing after surgery of impacted lower third molar? a systematic review and meta-analysis Via Journal of Oral and Maxillofacial Surgery Platelet concentrate generation protocols have undergone several modifications in recent years; in light of this news development, this study review aims to evaluated the effects of platelet-rich fibrin (PRF) and the new centrifugation protocols, advanced platelet-rich fibrin (A-PRF) and leukocite platelet-rich fibrin (L-PRF), after extraction of impacted mandibular third molar. Specifically, we assessed pain control, edema, trismus, and soft-tissue healing, and also measured the degree of periodontal regeneration adjacent to the second molar. (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Treatment of sagittal fracture of the mandibular condyle using resorbable-screw osteosynthesis

alwin shared this article with you from Inoreader Treatment of sagittal fracture of the mandibular condyle using resorbable-screw osteosynthesis Via Journal of Oral and Maxillofacial Surgery This study aimed to explore the applicability of resorbable-screw osteosynthesis in the treatment of SFMC. (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Accuracy and precision of the CTA perforator localization technique for virtual surgical planning of composite osteocutaneous fibular free flaps in head and neck reconstruction.

alwin shared this article with you from Inoreader Accuracy and precision of the CTA perforator localization technique for virtual surgical planning of composite osteocutaneous fibular free flaps in head and neck reconstruction. Via Journal of Oral and Maxillofacial Surgery Virtual surgical planning (VSP), computer aided design/computer aided modeling (CAD/CAM), and three-dimensional (3D) printing technology have been shown to improve surgical accuracy and efficiency in head and neck reconstruction. However, persisting criticism of the technology is that it does not adequately address the soft-tissue related aspects of the reconstructive surgery. Prior publication on the computed tomographic angiography (CTA) perforator localization technique has demonstrated how soft tissue planning can be incorporated directly into existing VSP workflows. (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Is the Er:YAG laser effective in reducing pain, edema and trismus after removal of impacted mandibular third molars? A meta-analysis.

alwin shared this article with you from Inoreader Is the Er:YAG laser effective in reducing pain, edema and trismus after removal of impacted mandibular third molars? A meta-analysis. Via Journal of Oral and Maxillofacial Surgery : Removal of impacted third molars, can be associated with complications such as pain, edema, trismus, that can increase the morbidity of this procedure. The purpose of this study is to determine whether the Er:YAG laser is effective in reducing pain, swelling and trismus compared to rotary instruments in removing impacted lower third molars (3 LM`s). (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Open Reduction Internal Fixation of Mandibular Condylar Fractures: Factors Influencing Radiographic Anatomical Reduction

alwin shared this article with you from Inoreader Open Reduction Internal Fixation of Mandibular Condylar Fractures: Factors Influencing Radiographic Anatomical Reduction Via Journal of Oral and Maxillofacial Surgery Mandible fractures occur frequently, accounting for approximately 70% of all facial fractures. Of those, fractures of the mandibular condyle account for 25-35%.1,2 Over several decades, there has been much controversy over the standard treatment method for condylar fractures, with increasing support for open reduction internal fixation (ORIF). The aim of this study is to determine negative and positive factors that may influence radiographic reduction outcomes after ORIF of mandibular condylar fractures. (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Is inferior alveolar nerve block needed to perform implant surgery in the posterior mandible? A randomized controlled trial.

alwin shared this article with you from Inoreader Is inferior alveolar nerve block needed to perform implant surgery in the posterior mandible? A randomized controlled trial. Via Journal of Oral and Maxillofacial Surgery This study aimed to compare the efficacy of the 2 techniques using articaine 4% with epinephrine 1:100,000. (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Intraoperative flap warming: The novel use of a sterile cardiac forced warm air blanket for maintaining optimal flap perfusion.

alwin shared this article with you from Inoreader Intraoperative flap warming: The novel use of a sterile cardiac forced warm air blanket for maintaining optimal flap perfusion. Via Journal of Oral and Maxillofacial Surgery The two-team approach in major head and neck/reconstructive surgery can occasionally lead to delays between flap harvest and detachment, due to the complexity and length of the ablative procedure. In order to minimize the potential for flap cooling and the adverse impact on microcirculation, active warming can be beneficial.(1) Intraoperative flap warming to either maintain or improve circulation during free flap harvesting has been performed with a variety of passive and active techniques,(2) however limitations such as a lack of consistent temperature regulation, lack of sterility, inability to directly visualise the flap or the need for acquisition of new equipment for a niche area meant that an ideal solution was lacking. (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Pseudoaneurysms after Le Fort I Osteotomy at a Single High-surgical-volume Institution

alwin shared this article with you from Inoreader Pseudoaneurysms after Le Fort I Osteotomy at a Single High-surgical-volume Institution Via Journal of Oral and Maxillofacial Surgery The Le Fort I maxillary osteotomy remains a workhorse surgical technique for addressing dentofacial deformities; however, significant complications can arise. One of the most serious complications is a pseudoaneurysm that results from injury to a terminal branch of the internal maxillary artery. The bleeding episodes normally develop 10 days to 4 weeks post-hospital discharge. Typically, these are minor sentinel bleeding preceding a hemorrhagic episode that results in an emergency room visit. While rare, significant morbidity has been reported, and bleeding can be rapid and in some instances mortal. (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Training the pronunciation of L2 vowels under different conditions: the use of non-lexical materials and masking noise

alwin shared this article with you from Inoreader Training the pronunciation of L2 vowels under different conditions: the use of non-lexical materials and masking noise Via Phonetica Phonetica. 2022 Apr 15. doi: 10.1515/phon-2022-2018. Online ahead of print.ABSTRACTThe current study extends traditional perceptual high-variability phonetic training (HVPT) in a foreign language learning context by implementing a comprehensive training paradigm that combines perception (discrimination and identification) and production (immediate repetition) training tasks and by exploring two potentially enhancing training conditions: the use of non-lexical training stimuli and the presence of masking noise during production training. We assessed training effects on L1-Spanish/Catalan bilingual EFL learners' production of a difficult English vowel contrast (/æ/-/ʌ/). The participants (N = 62) were randomly assigned to either non-lexical (N = 24) or lexical (N = 24) training and were fu... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Cellular fibroadenoma versus phyllodes tumors: A pre‐operative diagnostic approach based on radiological and cytological features

alwin shared this article with you from Inoreader Cellular fibroadenoma versus phyllodes tumors: A pre‐operative diagnostic approach based on radiological and cytological features Via Diagnostic Cytopathology Abstract Objective This study has been designed in an effort to identify the clinico-radiological and cytological features that could effectively help in differentiating cellular fibroadenoma (CFA) and phyllodes tumors (PT), which have several overlapping characteristics. Method Histologically proven cases of CFA and PT were reviewed. Cytological features were assessed and categorized. Clinical and radiological details were also evaluated and he the two groups were compared statistically. Results A total of 43 FA and 52 PT were specimens were reviewed. Mean age and tumor size for CFA and PT were 26.05 and 36.94 years, and 3.7 and 6.4 cm, respectively. Univariate analysis and regression models revealed that age >30 years, BIRADS grade of 4 or more, marked cellularity of stromal fragments, more than 30% spindle cells in background cell population and presence of traversing blood vessels in stromal fragments increased the odds of a tumor being phyllodes. The binary logistic regression model was able to predict PT accurately in 87.2% cases (p <  .001). Conclusion PT and CFA could be differentiated if cytological findings are cautiously correlated clinically and radiologically. Age, BIRADS category along with assessment of stromal fragments and background population can effectively distinguish between CFA and PT. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.