Laryngeal chondrosarcoma: A systematic review of 592 cases
[image: cover.gif?v=1&s=18911bcadec2567e9064b19b] Objectives/Hypothesis Laryngeal chondrosarcomas are rare entities that arise from the cartilaginous structures of the larynx, including the cricoid, thyroid cartilage, epiglottis, and arytenoid cartilages. These tumors represent a minority of malignancies involving the larynx and can be mistaken for benign pathologies. The treatment has historically been surgical excision, often by total laryngectomy. This review investigates treatment modalities and patient outcomes. Study Design Systematic review using PubMed/MEDLINE and EMBASE... περισσότερα »
The ethics of running multiple operating rooms simultaneously: Is this Ghost surgery?
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The ethics of running multiple operating rooms simultaneously: Is this Ghost surgery?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 18 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PnMIF2 via IFTTT
Laryngeal chondrosarcoma: A systematic review of 592 cases
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 18 δευτερόλεπτα
Objectives/Hypothesis Laryngeal chondrosarcomas are rare entities that arise from the cartilaginous structures of the larynx, including the cricoid, thyroid cartilage, epiglottis, and arytenoid cartilages. These tumors represent a minority of malignancies involving the larynx and can be mistaken for benign pathologies. The treatment has historically been surgical excision, often by total laryngectomy. This review investigates […]
Characteristics of superior orbital subperiosteal abscesses in children
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 18 δευτερόλεπτα
Objectives/Hypothesis Superior pediatric orbital subperiosteal abscesses (SPAs) are less common than medial ones, and clinical features specific to patients with superior SPAs have not been well defined. Clinical characteristics between patients with superior and medial SPAs are compared to determine whether superior location is a risk factor for surgical intervention. Study Design Retrospective cohort study. […]
Vestibular evoked myogenic potential testing as an objective measure of vestibular stimulation with cochlear implants
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 18 δευτερόλεπτα
Objectives/Hypothesis To determine if vestibular potentials could be elicited with electrical stimulation from cochlear implants. Study Design Prospective cohort study. Methods Vestibular responsiveness to electrical stimulation from cochlear implants was assessed via vestibular evoked myogenic potential (VEMP) testing in 53 pediatric and young adult patients. Results Thirty-one participants (58%) showed at least one vestibular potential […]
What is the role of preoperative imaging for cochlear implants in adults with postlingual deafness?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 18 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YmuOJX via IFTTT
The transcricothyroid injection laryngoplasty via contralateral paramedian approach
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 18 δευτερόλεπτα
The usefulness of via Auris Nasus Larynx Source:Auris Nasus Larynx Author(s): Byung-Joon Chun, Mi-Ran Shim, Yeon-Shin Hwang, Young-Hoon Joo, Young-Hak Park, Dong-Il Sun ObjectiveSeveral laryngeal injection techniques are technically difficult and have limitations. In this study, we modified a transcricothyroid approach for injections to enhance needle visualization during procedures. The objective of this study was […]
Development and application of a rapid detection system for human papillomavirus and Herpes simplex virus -2 by loop-mediated isothermal amplification assay.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 18 δευτερόλεπτα
Development and application of a rapid detection system for human papillomavirus and Herpes simplex virus -2 by loop-mediated isothermal amplification assay.: Microb Pathog. 2016 Jun; Authors: Yang JF, Zhao CZ, Lu KX Abstract Human papillomavirus (HPV) infection is an important factor that causes cervical cancer and non-melanoma skin cancer (NMSC), while HSV-2 plays an important […]
Human beta-defensin 1, 2 and 3 production by amniotic epithelial cells with respect to human papillomavirus (HPV) infection, HPV oncogenic potential and the mode of delivery.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 18 δευτερόλεπτα
Human beta-defensin 1, 2 and 3 production by amniotic epithelial cells with respect to human papillomavirus (HPV) infection, HPV oncogenic potential and the mode of delivery.: Microb Pathog. 2016 Jun ; Authors: Szukiewicz D, Alkhalayla H, Pyzlak M, Watroba M, Szewczyk G, Wejman J Abstract BACKGROUND: Human beta-defensins (HBD) produced by human amniotic epithelial cells […]
Dacomitinib-induced Dermatologic and Gastrointestinal Adverse Events
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 18 δευτερόλεπτα
A Phase II Study (ARCHER 1042) to Evaluate Prophylactic Treatment of Dacomitinib-induced Dermatologic and Gastrointestinal Adverse Events in Advanced Non-Small-Cell Lung Cancer.: Ann Oncol. 2016 Jun ; Authors: Lacouture ME, Keefe DM, Sonis S, Jatoi A, Gernhardt D, Wang T, Doherty JP, Giri N, Nadanaciva S, O’Connell J, Sbar E, Piperdi B, Garon EB Abstract […]
Perception of Small Frequency Differences in Children with Auditory Processing Disorder or Specific Language Impairment
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 18 δευτερόλεπτα
Perception of Small Frequency Differences in Children with Auditory Processing Disorder or Specific Language Impairment: Abstract: Background: Frequency discrimination is often impaired in children developing language atypically. However, findings in the detection of small frequency changes in these children are conflicting. Previous studies on children’s auditory perceptual abilities usually involved establishing differential sensitivity thresholds in […]
European Annals of Otorhinolaryngology Head & Neck Diseases
Recently published articles from European Annals of Otorhinolaryngology, Head and Neck Diseases ------------------------------ Hearing-related quality of life outcomes for Singaporean children using hearing aids or cochlear implants Available online 3 June 2016 V. Looi | Z.Z. Lee | J.H.Y. Loo The Children Using Hearing Devices Quality of Life Questionnaire (CuHDQOL) is a new parent-administered hearing-specific questionnaire for children fitted with hearing devices. The aim of this study... ------------------------------ ECAP analysis in cochlear implant patients as a function of ... περισσότερα »
European Annals of Otorhinolaryngology Head & Neck Diseases
Recently published articles from European Annals of Otorhinolaryngology, Head and Neck Diseases ------------------------------ Hearing-related quality of life outcomes for Singaporean children using hearing aids or cochlear implants Available online 3 June 2016 V. Looi | Z.Z. Lee | J.H.Y. Loo The Children Using Hearing Devices Quality of Life Questionnaire (CuHDQOL) is a new parent-administered hearing-specific questionnaire for children fitted with hearing devices. The aim of this study... ------------------------------ ECAP analysis in cochlear implant patients as a function of ... περισσότερα »
European Annals of Otorhinolaryngology Head & Neck Diseases
Analyse des cas cliniques soumis aux via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: June 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 3 Author(s): O. Laccourreye, P. Bonfils, F. Denoyelle, R. Garrel, R. Jankowski, A. Karkas, M. Makeieff, C. Righini, C. Vincent, C. Martin ObjectifsÉvaluer les défauts, le taux d’acceptation et les raisons du rejet des cas cliniques soumis pour publication aux European Annals of Otorhinolaryngology Head & Neck D... περισσότερα »
Courbe d’apprentissage de la septoplastie endoscopique
Courbe d’apprentissage de la septoplastie endoscopique via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: June 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 3 Author(s): C. Champagne, S. Ballivet de Régloix, L. Genestier, A. Crambert, O. Maurin, Y. Pons ButsLe but de l’étude était d’évaluer la courbe d’apprentissage de la septoplastie endoscopique pour un chirurgien sénior déjà formé à la chirurgie sinusienne endonasale.Matériel et méthodesEntre no... περισσότερα »
Les résultats obtenus ont montré l’intérêt du port de l’AA controlatérale à l’IC en termes d’amélioration de la perception auditive dans le calme et le bruit. En cas d’audition résiduelle controlatérale à l’IC, une AA doit être proposée ; et dans les surdités bilatérales progressives, l’IC doit être proposée dès que le patient perd le bénéfice de l’AA d’un des côtés.
Étude du bénéfice apporté par l’appareillage audioprothétique controlatéral chez les adultes implantés cochléaires via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: June 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 3 Author(s): D. Bouccara, E. Blanchet, P.-E. Waterlot, M. Smadja, B. Frachet, B. Meyer, O. Sterkers ObjectifsL’objectif de cette étude était de montrer l’intérêt et les bénéfices obtenus par l’utilisation d’une aide auditive controlaté... περισσότερα »
Are There Compounds in Herbs That Can Stimulate Thyroid Function in Hashimoto's Thyroiditis?
Are There Compounds in Herbs That Can Stimulate Thyroid Function in Hashimoto's Thyroiditis?: Clinical Thyroidology Jun 2016, Vol. 28, No. 6: 184-185.
Thyroxine Reduces Epicardial Fat Tissue Mass in Subclinical Hypothyroidism
• Clinical Thyroidology June 2016, Vol. 28, No. 6, 181-183 Posted online on June 10, 2016. (doi:10.1089/ct.2016;28.181-183) View Table of Contents | [image: RSS] TOC, Citation What is RSS? | Email Alert Author information Charles H. Emerson Sayin I, Erkan AF, Ekici B, Kutuk U, Corakci A, Tore HF. Thickening of the epicardial adipose tissue can be alleviated by thyroid hormone replacement therapy in patients with subclinical hypothyroidism. Kardiol Pol. April 26, 2016 [Epub ahead of print]. [image: Free first page]
Thyroid Hormone Nonadherence in Pregnancy
•What Predicts Thyroid Hormone Nonadherence in Pregnancy? Clinical Thyroidology June 2016, Vol. 28, No. 6, 178-180 Posted online on June 10, 2016. (doi:10.1089/ct.2016;28.178-180) View Table of Contents | [image: RSS] TOC, Citation What is RSS? | Email Alert Author information Elizabeth N. Pearce Juch H, Lupattelli A, Ystrom E, Verheyen S, Nordeng H. Medication adherence among pregnant women with hypothyroidism—missed opportunities to improve reproductive health? A cross-sectional, web-based study. Patient Educ Couns. April 11, 2016 [Epub ahead of print]. [image: Free first page]
Normalization of TSH in Women with Mild Subclinical Hypothyroidism During Pregnancy Bears a Low Risk of Overtreatment
• Clinical Thyroidology June 2016, Vol. 28, No. 6, 174-177 Posted online on June 10, 2016. (doi:10.1089/ct.2016;28.174-177) View Table of Contents | [image: RSS] TOC, Citation What is RSS? | Email Alert Author information Tim I.M. Korevaar Maraka S, Singh Ospina NM, O'Keeffe DT, Rodriguez-Gutierrez R, Espinosa De Ycaza AE, Wi C, Juhn YJ, Coddington C, Montori V, Stan MN. Effects of levothyroxine therapy on pregnancy outcomes in women with subclinical hypothyroidism. Thyroid. May 16, 2016 [Epub ahead of print]. [image: Free first page]
A High Incidence of Thyroid Cancer in Children
•Mass Ultrasound Screening Yields a High Incidence of Thyroid Cancer in Children Exposed to the Fukushima Nuclear Accident Clinical Thyroidology June 2016, Vol. 28, No. 6, 171-173 Posted online on June 10, 2016. (doi:10.1089/ct.2016;28.171-173) View Table of Contents | [image: RSS] TOC, Citation What is RSS? | Email Alert Author information Angela M. Leung Suzuki S, Suzuki S, Fukushima T, Midorikawa S, Shimura H, Matsuzuka T, Ishikawa T, Takahashi H, Ohtsuru A, Sakai A, Hosoya M, Yasumura S, Nollet KE, Ohira T, Ohto H, Abe M, Kamiya K, Yamashita S. Comprehensive survey results of ... περισσότερα »
Noninvasive Encapsulated Follicular Variant of Papillary Thyroid Cancer May Not Be a Cancer
•Clinical Thyroidology June 2016, Vol. 28, No. 6, 163-166 Posted online on June 10, 2016. (doi:10.1089/ct.2016;28.163-166) Author information Jerome M. Hershman Nikiforov YE, Seethala RR, Tallini G, Baloch ZW, Basolo F, Thompson LD, Barletta JA, Wenig BM, Al Ghuzlan A, Kakudo K, Giordano TJ, Alves VA, Khanafshar E, Asa SL, El-Naggar AK, Gooding WE, Hodak SP, Lloyd RV, Maytal G, Mete O, Nikiforova MN, Nosé V, Papotti M, Poller DN, Sadow PM, Tischler AS, Tuttle RM, Wall KB, LiVolsi VA, Randolph GW, Ghossein RA. Nomenclature revision for encapsulated follicular variant of papillary thyr... περισσότερα »
Reclassification of Noninvasive Follicular Variant of Papillary Thyroid Carcinoma
Reclassification of Noninvasive Follicular Variant of Papillary Thyroid Carcinoma As a Benign Condition Will Reduce the Incidence of Malignancy in the Indeterminate FNA Categories: Clinical Thyroidology Jun 2016, Vol. 28, No. 6: 167-170. [image: Free first page]
An Enlarging Lung Mass
Unexpected Pathology of an Enlarging Lung Mass in a Patient with Metastatic Mixed Papillary and Oncocytic Variant Thyroid Carcinoma: Clinical Thyroidology Jun 2016, Vol. 28, No. 6: 186-190. [image: Free first page]
Pediatric nasal orbital cellulitis
in Shenzhen (South China): Etiology, management, and outcomes via International Journal of Pediatric Otorhinolaryngology Publication date: August 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 87 Author(s): Pan Hongguang, Li Lan, Wu Zebin, Chen Guowei ObjectivesThe study aimed to investigate the clinical characteristics, diagnosis, and treatment of orbital cellulitis in children in Shenzhen, China, and to improve the experience of antibiotic therapy for the treatment of orbital cellulites.MethodsThis retrospective study reviewed data from 20 children admi... περισσότερα »
Local allergic rhinitis (LAR)
Update on local allergic rhinitis via International Journal of Pediatric Otorhinolaryngology Publication date: August 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 87 Author(s): Niyazi Altıntoprak, Murat Kar, Nuray Bayar Muluk, Tugba Oktemer, Kagan Ipci, Leman Birdane, Mitat Aricigil, Mehmet Senturk, Sameer Ali Bafaqeeh, Cemal Cingi We here provide an update on the literature regarding local allergic rhinitis (LAR). In reviewing LAR, we have included an updated definition, classifications, mechanisms, comorbidities, and recommendations for diagnosis and ... περισσότερα »
The transcricothyroid injection laryngoplasty via contralateral paramedian approach
The usefulness of via Auris Nasus Larynx *Source:*Auris Nasus Larynx Author(s): Byung-Joon Chun, Mi-Ran Shim, Yeon-Shin Hwang, Young-Hoon Joo, Young-Hak Park, Dong-Il Sun ObjectiveSeveral laryngeal injection techniques are technically difficult and have limitations. In this study, we modified a transcricothyroid approach for injections to enhance needle visualization during procedures. The objective of this study was to investigate the efficacy of this alternative injection technique.MethodsWe performed a retrospective analysis of 51 patients who had undergone injection laryngoplast... περισσότερα »
Development and application of a rapid detection system for human papillomavirus and Herpes simplex virus -2 by loop-mediated isothermal amplification assay.
Development and application of a rapid detection system for human papillomavirus and Herpes simplex virus -2 by loop-mediated isothermal amplification assay.: Microb Pathog. 2016 Jun; Authors: Yang JF, Zhao CZ, Lu KX Abstract Human papillomavirus (HPV) infection is an important factor that causes cervical cancer and non-melanoma skin cancer (NMSC), while HSV-2 plays an important role when HR-HPV triggers the cancer. Thus, a quick and convenient assay in the detection of HPV and HSV-2in the screening of HPV and HSV-2 infection is required. Two respective HPV and HSV-2 detection me... περισσότερα »
Human beta-defensin 1, 2 and 3 production by amniotic epithelial cells with respect to human papillomavirus (HPV) infection, HPV oncogenic potential and the mode of delivery.
Human beta-defensin 1, 2 and 3 production by amniotic epithelial cells with respect to human papillomavirus (HPV) infection, HPV oncogenic potential and the mode of delivery.: Microb Pathog. 2016 Jun ; Authors: Szukiewicz D, Alkhalayla H, Pyzlak M, Watroba M, Szewczyk G, Wejman J Abstract BACKGROUND: Human beta-defensins (HBD) produced by human amniotic epithelial cells (HAEC) co-create an innate antiviral immune response in the materno-placento-fetal unit. Oncogenic potential of HPV may reflect its ability to avoid immune recognition. In this study we assessed the risk of HAEC i... περισσότερα »
Dacomitinib-induced Dermatologic and Gastrointestinal Adverse Events
A Phase II Study (ARCHER 1042) to Evaluate Prophylactic Treatment of Dacomitinib-induced Dermatologic and Gastrointestinal Adverse Events in Advanced Non-Small-Cell Lung Cancer.: Ann Oncol. 2016 Jun ; Authors: Lacouture ME, Keefe DM, Sonis S, Jatoi A, Gernhardt D, Wang T, Doherty JP, Giri N, Nadanaciva S, O'Connell J, Sbar E, Piperdi B, Garon EB Abstract BACKGROUND: ARCHER 1042, a randomized phase II trial, explored the impact of prophylactic treatment on select dermatologic adverse events of interest (SDAEI), diarrhea, and mucositis associated with dacomitinib, an oral irreversib... περισσότερα »
Perception of Small Frequency Differences in Children with Auditory Processing Disorder or Specific Language Impairment
Perception of Small Frequency Differences in Children with Auditory Processing Disorder or Specific Language Impairment: Abstract:*Background:* Frequency discrimination is often impaired in children developing language atypically. However, findings in the detection of small frequency changes in these children are conflicting. Previous studies on children’s auditory perceptual abilities usually involved establishing differential sensitivity thresholds in sample populations who were not tested for auditory deficits. To date, there are no data comparing suprathreshold frequency ... περισσότερα »
Factors Affecting Speech Discrimination in Children with Cochlear Implants: Evidence from Early-Implanted Infants
Factors Affecting Speech Discrimination in Children with Cochlear Implants: Evidence from Early-Implanted Infants: Abstract:*Background:* To learn words and acquire language, children must be able to discriminate and correctly perceive phonemes. Although there has been much research on the general language outcomes of children with cochlear implants (CIs), little is known about the development of speech perception with regard to specific speech processes, such as speech discrimination. *Purpose:* The purpose of this study was to investigate the development of speech discrim... περισσότερα »
Investigating the Interaction between Dichotic Deficits and Cognitive Abilities Using the Dichotic Digits difference Test (DDdT) Part 2
Investigating the Interaction between Dichotic Deficits and Cognitive Abilities Using the Dichotic Digits difference Test (DDdT) Part 2: Abstract:*Background:* The Dichotic Digits difference Test (DDdT) was developed to investigate the relationship between dichotic processing and cognitive abilities and, through the use of differential test scores, to provide professionals with a clinical tool that could aid in differentiation of clients with genuine dichotic deficits from those where cognitive disorders affect test performance. The DDdT consists of four subtests: dichotic fre... περισσότερα »
The Dichotic Digits difference Test (DDdT): Development, Normative Data, and Test‐Retest Reliability Studies Part 1
The Dichotic Digits difference Test (DDdT): Development, Normative Data, and Test‐Retest Reliability Studies Part 1: Abstract:*Background:* The dichotic digits test is one of the most widely used assessment tools for central auditory processing disorder. However, questions remain concerning the impact of cognitive factors on test results. *Purpose:* To develop the Dichotic Digits difference Test (DDdT), an assessment tool that could differentiate children with cognitive deficits from children with genuine dichotic deficits based on differential test results. The DDdT consis... περισσότερα »
Perceptions Toward Internet-Based Delivery of Hearing Aids among Older Hearing-Impaired Adults
Perceptions Toward Internet-Based Delivery of Hearing Aids among Older Hearing-Impaired Adults: Abstract:*Background:* Despite evidence that hearing aids can improve the social and psychological functioning of older hearing-impaired adults, hearing aid uptake is low. High cost of hearing aids and poor access to audiology services in rural areas are potential barriers to hearing aid acquisition. Methods of hearing aid delivery deviating from the traditional clinician-based model have been available to consumers for many years. One such method is Internet hearing aid sales. How... περισσότερα »
Clinical Outcomes of the Cochlear™ Nucleus® 5 Cochlear Implant System and SmartSound™ 2 Signal Processing
Clinical Outcomes of the Cochlear™ Nucleus® 5 Cochlear Implant System and SmartSound™ 2 Signal Processing: Abstract:*Background:* While published data exist regarding cochlear implant (CI) outcomes from large academic programs, evidence of benefit based on national, multicenter clinical trials is needed for information regarding typical patient outcomes of devices implanted by U.S. centers representing larger academic to smaller hospital-based programs. *Purpose:* This nationwide trial evaluated outcomes in a group of newly implanted adult recipients of the Cochlear™ Nucleu... περισσότερα »
Characteristics of superior orbital subperiosteal abscesses in children
Objectives/Hypothesis Superior pediatric orbital subperiosteal abscesses (SPAs) are less common than medial ones, and clinical features specific to patients with superior SPAs have not been well defined. Clinical characteristics between patients with superior and medial SPAs are compared to determine whether superior location is a risk factor for surgical intervention. Study Design Retrospective cohort study. Methods The target population consisted of patients diagnosed with an SPA and seen by the pediatric otolaryngology service at a tertiary children's hospital between Januar... περισσότερα »
Vestibular evoked myogenic potential testing as an objective measure of vestibular stimulation with cochlear implants
[image: cover.gif?v=1&s=18911bcadec2567e9064b19b] Objectives/Hypothesis To determine if vestibular potentials could be elicited with electrical stimulation from cochlear implants. Study Design Prospective cohort study. Methods Vestibular responsiveness to electrical stimulation from cochlear implants was assessed via vestibular evoked myogenic potential (VEMP) testing in 53 pediatric and young adult patients. Results Thirty-one participants (58%) showed at least one vestibular potential in response to acoustic stimulation; 33 (62%) had an electrically evoked vestibular respon... περισσότερα »
What is the role of preoperative imaging for cochlear implants in adults with postlingual deafness?
from #ORL via xlomafota13 on Inoreader http://ift.tt/1YmuOJX via IFTTT
Characteristics of superior orbital subperiosteal abscesses in children
Objectives/Hypothesis Superior pediatric orbital subperiosteal abscesses (SPAs) are less common than medial ones, and clinical features specific to patients with superior SPAs have not been well defined. Clinical characteristics between patients with superior and medial SPAs are compared to determine whether superior location is a risk factor for surgical intervention. Study Design Retrospective cohort study. Methods The target population consisted of patients diagnosed with an SPA and seen by the pediatric otolaryngology service at a tertiary children's hospital between Januar... περισσότερα »
Vestibular evoked myogenic potential testing as an objective measure of vestibular stimulation with cochlear implants
[image: cover.gif?v=1&s=18911bcadec2567e9064b19b] Objectives/Hypothesis To determine if vestibular potentials could be elicited with electrical stimulation from cochlear implants. Study Design Prospective cohort study. Methods Vestibular responsiveness to electrical stimulation from cochlear implants was assessed via vestibular evoked myogenic potential (VEMP) testing in 53 pediatric and young adult patients. Results Thirty-one participants (58%) showed at least one vestibular potential in response to acoustic stimulation; 33 (62%) had an electrically evoked vestibular respon... περισσότερα »
What is the role of preoperative imaging for cochlear implants in adults with postlingual deafness?
from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1YmuOJX via IFTTT
Critical review on retrospective and prospective changes in antifungal susceptibility testing for dermatophytes
Summary Antifungal susceptibility testing is a progressive field of mycology with respect to dermatophytes as well as non-dermatophytes. Documentation and approval regarding standardisation of *in vitro* susceptibility testing have been done by different governing bodies such as Clinical and Laboratory Standards Institute, European Committee on Antimicrobial Susceptibility Testing and British Society of Antimicrobial Chemotherapy. The process of standardisation and approval started in 1985 with certain amendments in 2002 and 2004. In case of dermatophytes, antifungal susceptibilit... περισσότερα »
Veneers Tooth Whitening and fillings at BIDC
The post Veneers Tooth Whitening and fillings at BIDC appeared first on Family Dentistry and Cosmetic Surgery Clinic. http://ift.tt/1U8tmuN
The transcricothyroid injection laryngoplasty via contralateral paramedian approach
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 38 δευτερόλεπτα
The usefulness of via Auris Nasus Larynx Source:Auris Nasus LarynxAuthor(s): Byung-Joon Chun, Mi-Ran Shim, Yeon-Shin Hwang, Young-Hoon Joo, Young-Hak Park, Dong-Il SunObjectiveSeveral laryngeal injection techniques are technically difficult and have limitations. In this study, we modified a transcricothyroid approach for injections to enhance needle visualization during procedures. The objective of this study was to investigate the […]
Development and application of a rapid detection system for human papillomavirus and Herpes simplex virus -2 by loop-mediated isothermal amplification assay.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 38 δευτερόλεπτα
Development and application of a rapid detection system for human papillomavirus and Herpes simplex virus -2 by loop-mediated isothermal amplification assay.: Microb Pathog. 2016 Jun; Authors: Yang JF, Zhao CZ, Lu KX Abstract Human papillomavirus (HPV) infection is an important factor that causes cervical cancer and non-melanoma skin cancer (NMSC), while HSV-2 plays an important […]
Human beta-defensin 1, 2 and 3 production by amniotic epithelial cells with respect to human papillomavirus (HPV) infection, HPV oncogenic potential and the mode of delivery.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 38 δευτερόλεπτα
Human beta-defensin 1, 2 and 3 production by amniotic epithelial cells with respect to human papillomavirus (HPV) infection, HPV oncogenic potential and the mode of delivery.: Microb Pathog. 2016 Jun ; Authors: Szukiewicz D, Alkhalayla H, Pyzlak M, Watroba M, Szewczyk G, Wejman J Abstract BACKGROUND: Human beta-defensins (HBD) produced by human amniotic epithelial cells […]
Dacomitinib-induced Dermatologic and Gastrointestinal Adverse Events
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 38 δευτερόλεπτα
A Phase II Study (ARCHER 1042) to Evaluate Prophylactic Treatment of Dacomitinib-induced Dermatologic and Gastrointestinal Adverse Events in Advanced Non-Small-Cell Lung Cancer.: Ann Oncol. 2016 Jun ; Authors: Lacouture ME, Keefe DM, Sonis S, Jatoi A, Gernhardt D, Wang T, Doherty JP, Giri N, Nadanaciva S, O’Connell J, Sbar E, Piperdi B, Garon EB Abstract […]
Perception of Small Frequency Differences in Children with Auditory Processing Disorder or Specific Language Impairment
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 38 δευτερόλεπτα
Perception of Small Frequency Differences in Children with Auditory Processing Disorder or Specific Language Impairment: Abstract: Background: Frequency discrimination is often impaired in children developing language atypically. However, findings in the detection of small frequency changes in these children are conflicting. Previous studies on children’s auditory perceptual abilities usually involved establishing differential sensitivity thresholds in […]
Factors Affecting Speech Discrimination in Children with Cochlear Implants: Evidence from Early-Implanted Infants
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 38 δευτερόλεπτα
Factors Affecting Speech Discrimination in Children with Cochlear Implants: Evidence from Early-Implanted Infants: Abstract: Background: To learn words and acquire language, children must be able to discriminate and correctly perceive phonemes. Although there has been much research on the general language outcomes of children with cochlear implants (CIs), little is known about the development of […]
Investigating the Interaction between Dichotic Deficits and Cognitive Abilities Using the Dichotic Digits difference Test (DDdT) Part 2
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 38 δευτερόλεπτα
Investigating the Interaction between Dichotic Deficits and Cognitive Abilities Using the Dichotic Digits difference Test (DDdT) Part 2: Abstract: Background: The Dichotic Digits difference Test (DDdT) was developed to investigate the relationship between dichotic processing and cognitive abilities and, through the use of differential test scores, to provide professionals with a clinical tool that could […]
The Dichotic Digits difference Test (DDdT): Development, Normative Data, and Test‐Retest Reliability Studies Part 1
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 38 δευτερόλεπτα
The Dichotic Digits difference Test (DDdT): Development, Normative Data, and Test‐Retest Reliability Studies Part 1: Abstract: Background: The dichotic digits test is one of the most widely used assessment tools for central auditory processing disorder. However, questions remain concerning the impact of cognitive factors on test results. Purpose: To develop the Dichotic Digits difference Test […]
Perceptions Toward Internet-Based Delivery of Hearing Aids among Older Hearing-Impaired Adults
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 38 δευτερόλεπτα
Perceptions Toward Internet-Based Delivery of Hearing Aids among Older Hearing-Impaired Adults: Abstract: Background: Despite evidence that hearing aids can improve the social and psychological functioning of older hearing-impaired adults, hearing aid uptake is low. High cost of hearing aids and poor access to audiology services in rural areas are potential barriers to hearing aid acquisition. […]
Clinical Outcomes of the Cochlear™ Nucleus® 5 Cochlear Implant System and SmartSound™ 2 Signal Processing
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 38 δευτερόλεπτα
Clinical Outcomes of the Cochlear™ Nucleus® 5 Cochlear Implant System and SmartSound™ 2 Signal Processing: Abstract: Background: While published data exist regarding cochlear implant (CI) outcomes from large academic programs, evidence of benefit based on national, multicenter clinical trials is needed for information regarding typical patient outcomes of devices implanted by U.S. centers representing larger […]
In vitro evaluation of antifungal susceptibility and keratinase, elastase, lipase and DNase activities of different dermatophyte species isolated from clinical specimens in Iran
Summary The aims of this study were to evaluate the enzymatic activity of various dermatophyte species and their antifungal susceptibility profiles. A total of 60 dermatophyte isolates, including *Trichophyton mentagrophytes*, *Trichophyton rubrum*, *Microsporum canis* and *Microsporum gypseum*, were examined. Fungal isolates were analysed for the production of keratinase, lipase, elastase and deoxyribonuclease (DNase). A broth microdilution method was performed on the basis of M38-A2 Clinical and Laboratory Standards Institute (CLSI) guidelines. *T. mentagrophytes*, *M. canis* and... περισσότερα »
Fusarium sacchari, a cause of mycotic keratitis among sugarcane farmers – a series of four cases from North India
Summary The two most common filamentous fungi causing mycotic keratitis are *Aspergillus* and *Fusarium* spp. Around 70 *Fusarium* spp. are involved in causing human infections. In this study, four cases of keratitis in sugarcane farmers in India are being reported, caused by the sugar cane pathogen *Fusarium sacchari*, a species of the *Fusarium fujikuroi* species complex. Fusarial keratitis was established by potassium hydroxide/Calcofluor white wet mounts and fungal culture of corneal scrapings on conventional media. Final identification was done by genetic sequencing at CBS-KN... περισσότερα »
Epizootic and epidemic dermatophytose outbreaks caused by Trichophyton mentagrophytes from rabbits in Portugal, 2015
Summary We report an outbreak of dermatophytoses in rabbits, which was the origin of a dermatophytose epidemic in an agricultural school in central Portugal, affecting 15 people. Both the phenotypic characteristics and internal transcribed spacer (ITS) sequence of the dermatophytes isolated from the rabbits and patients were identical, suggesting that a single strain was responsible for both the epizootic and epidemic dermatophytoses and confirming that these two outbreaks were linked. The ITS sequences were also 100% identical to the ITS sequence of five strains isolated from rab... περισσότερα »
Identification and typing of the emerging pathogen Candida auris by matrix-assisted laser desorption ionisation time of flight mass spectrometry
Summary *Candida auris* is an emerging antifungal resistant yeast species causing nosocomial and invasive infections, emphasising the need of improved diagnostics and epidemiological typing methods. We show that MALDI-TOF VITEK-MS followed by amplified length polymorphisms allows for accurate species identification and subsequent epidemiological characterisation of strains encountered during potential outbreaks. from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1ZJO5Ua via IFTTT
Loss of p53 expression is accompanied by upregulation of beta-catenin in meningiomas: a concomitant reciprocal expression
Summary Crosstalk between Wnt and p53 signalling pathways in cancer has long been suggested. Therefore in this study we have investigated the involvement of these pathways in meningiomas by analysing their main effector molecules, beta-catenin and p53. Cellular expression of p53 and beta-catenin proteins and genetic changes in TP53 were analysed by immunohistochemistry, PCR/RFLP and direct sequencing of TP53 exon 4. All the findings were analysed statistically. Our analysis showed that 47.5% of the 59 meningiomas demonstrated loss of expression of p53 protein. Moderate and strong p... περισσότερα »
Functional roles of CSPG4/NG2 in chondrosarcoma
Summary CSPG4/NG2 is a multifunctional transmembrane protein with limited distribution in adult tissues including articular cartilage. The purpose of this study was to investigate the possible roles of CSPG4/NG2 in chondrosarcomas and to establish whether this molecule may have potential for targeted therapy. Stable knock-down of CSPG4/NG2 in the JJ012 chondrosarcoma cell line by shRNA resulted in decreased cell proliferation and migration as well as a decrease in gene expression of the MMP (matrix metalloproteinase) 3 protease and ADAMTS4 (aggrecanase). Chondrosarcoma cells in wh... περισσότερα »
In vitro evaluation of antifungal susceptibility and keratinase, elastase, lipase and DNase activities of different dermatophyte species isolated from clinical specimens in Iran
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Summary The aims of this study were to evaluate the enzymatic activity of various dermatophyte species and their antifungal susceptibility profiles. A total of 60 dermatophyte isolates, including Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis and Microsporum gypseum, were examined. Fungal isolates were analysed for the production of keratinase, lipase, elastase and deoxyribonuclease (DNase). A broth […]
Fusarium sacchari, a cause of mycotic keratitis among sugarcane farmers – a series of four cases from North India
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Summary The two most common filamentous fungi causing mycotic keratitis are Aspergillus and Fusarium spp. Around 70 Fusarium spp. are involved in causing human infections. In this study, four cases of keratitis in sugarcane farmers in India are being reported, caused by the sugar cane pathogen Fusarium sacchari, a species of the Fusarium fujikuroi species […]
Epizootic and epidemic dermatophytose outbreaks caused by Trichophyton mentagrophytes from rabbits in Portugal, 2015
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Summary We report an outbreak of dermatophytoses in rabbits, which was the origin of a dermatophytose epidemic in an agricultural school in central Portugal, affecting 15 people. Both the phenotypic characteristics and internal transcribed spacer (ITS) sequence of the dermatophytes isolated from the rabbits and patients were identical, suggesting that a single strain was responsible […]
Identification and typing of the emerging pathogen Candida auris by matrix-assisted laser desorption ionisation time of flight mass spectrometry
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Summary Candida auris is an emerging antifungal resistant yeast species causing nosocomial and invasive infections, emphasising the need of improved diagnostics and epidemiological typing methods. We show that MALDI-TOF VITEK-MS followed by amplified length polymorphisms allows for accurate species identification and subsequent epidemiological characterisation of strains encountered during potential outbreaks. from #Medicine-SfakianakisAlexandros via o.lakala70 on […]
Loss of p53 expression is accompanied by upregulation of beta-catenin in meningiomas: a concomitant reciprocal expression
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Summary Crosstalk between Wnt and p53 signalling pathways in cancer has long been suggested. Therefore in this study we have investigated the involvement of these pathways in meningiomas by analysing their main effector molecules, beta-catenin and p53. Cellular expression of p53 and beta-catenin proteins and genetic changes in TP53 were analysed by immunohistochemistry, PCR/RFLP and […]
Functional roles of CSPG4/NG2 in chondrosarcoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Summary CSPG4/NG2 is a multifunctional transmembrane protein with limited distribution in adult tissues including articular cartilage. The purpose of this study was to investigate the possible roles of CSPG4/NG2 in chondrosarcomas and to establish whether this molecule may have potential for targeted therapy. Stable knock-down of CSPG4/NG2 in the JJ012 chondrosarcoma cell line by shRNA […]
Veneers Tooth Whitening and fillings at BIDC
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The post Veneers Tooth Whitening and fillings at BIDC appeared first on Family Dentistry and Cosmetic Surgery Clinic. http://ift.tt/1U8tmuN from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PnJlxT via IFTTT
20Q: Pediatric Vestibular Disorders and the Role of the Audiologist
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
1. Pediatric assessment of dizziness? That’s something new for me. It’s new for a lot of us, but truth be told, there has never been a more exciting time to be in this area of Audiology. New research in pediatric vestibular assessment and management has opened our eyes to the developmental consequences of balance impairments. […]
20Q: Pediatric Vestibular Disorders and the Role of the Audiologist
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
1. Pediatric assessment of dizziness? That’s something new for me. It’s new for a lot of us, but truth be told, there has never been a more exciting time to be in this area of Audiology. New research in pediatric vestibular assessment and management has opened our eyes to the developmental consequences of balance impairments. […]
20Q: Pediatric Vestibular Disorders and the Role of the Audiologist
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
1. Pediatric assessment of dizziness? That’s something new for me. It’s new for a lot of us, but truth be told, there has never been a more exciting time to be in this area of Audiology. New research in pediatric vestibular assessment and management has opened our eyes to the developmental consequences of balance impairments. […]
AUC-Guided Vancomycin Dosing in Adolescent Patients with Suspected Sepsis
[image: cover.gif?v=1&s=181b27a31d0ca2da1556ca62] Abstract Vancomycin is a first-line treatment for beta-lactam resistant gram-positive bacterial infections. Understanding the pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of vancomycin in an adolescent population is of clinical importance in this often overlooked pediatric population. This retrospective study investigated vancomycin PK-PD in an adolescent cohort (12-18 years of age) of 463 patients (57% male, 81% white) admitted to the Intermountain Healthcare System between January 2006 and December 2013. Populat... περισσότερα »
The Pharmacometrician's Dilemma: The tension between mechanistic and empirical approaches in mathematical modelling and simulation – a continuation of the age-old dispute between rationalism and empiricism?
from Therapeutics via xlomafota13 on Inoreader http://ift.tt/1PVO5jY
Short-term effects of greater occipital nerve blocks in chronic migraine: A double-blind, randomised, placebo-controlled clinical trial
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background Greater occipital nerve (GON) blocks are widely used for the treatment of headaches, but quality evidence regarding their efficacy is scarce. Objective The objective of this article is to assess the short-term clinical efficacy of GON anaesthetic blocks in chronic migraine (CM) and to analyse their effect on pressure pain thresholds (PPTs) in different […]
Short-term effects of greater occipital nerve blocks in chronic migraine: A double-blind, randomised, placebo-controlled clinical trial
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Background Greater occipital nerve (GON) blocks are widely used for the treatment of headaches, but quality evidence regarding their efficacy is scarce. Objective The objective of this article is to assess the short-term clinical efficacy of GON anaesthetic blocks in chronic migraine (CM) and to analyse their effect on pressure pain thresholds (PPTs) in different […]
Loss of p53 expression is accompanied by upregulation of beta-catenin in meningiomas: a concomitant reciprocal expression
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Summary Crosstalk between Wnt and p53 signalling pathways in cancer has long been suggested. Therefore in this study we have investigated the involvement of these pathways in meningiomas by analysing their main effector molecules, beta-catenin and p53. Cellular expression of p53 and beta-catenin proteins and genetic changes in TP53 were analysed by immunohistochemistry, PCR/RFLP and […]
Functional roles of CSPG4/NG2 in chondrosarcoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Summary CSPG4/NG2 is a multifunctional transmembrane protein with limited distribution in adult tissues including articular cartilage. The purpose of this study was to investigate the possible roles of CSPG4/NG2 in chondrosarcomas and to establish whether this molecule may have potential for targeted therapy. Stable knock-down of CSPG4/NG2 in the JJ012 chondrosarcoma cell line by shRNA […]
Melanoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Melanoma: a cancer of the melanocyte, the cell that produces pigment in the skin. Melanoma is considered the most dangerous form of skin cancer, Melanoma is most common in people with fair skin, but can occur in people with all skin colors. Most melanomas present as a dark, mole-like spot that spreads and, unlike a […]
Idiopathic Inflammatory Myopathies: An update
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
2016-06-12T18-56-49Z Source: Journal of Interdisciplinary Histopathology Bulent KURT, Serdar TASDEMIR, Ertugrul CELIK, Kemal INAN. Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of disease with complex clinical features. It has been sub-classified as: (1) Dermatomyositis, (2) Polymyositis, and (3) Inclusion body myositis (IBM). Nowadays, there are some studies in literature suggest necrotizing autoimmune myopathy and […]
Short-term effects of greater occipital nerve blocks in chronic migraine: A double-blind, randomised, placebo-controlled clinical trial
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Background Greater occipital nerve (GON) blocks are widely used for the treatment of headaches, but quality evidence regarding their efficacy is scarce. Objective The objective of this article is to assess the short-term clinical efficacy of GON anaesthetic blocks in chronic migraine (CM) and to analyse their effect on pressure pain thresholds (PPTs) in different […]
Short-term effects of greater occipital nerve blocks in chronic migraine: A double-blind, randomised, placebo-controlled clinical trial
Background Greater occipital nerve (GON) blocks are widely used for the treatment of headaches, but quality evidence regarding their efficacy is scarce. Objective The objective of this article is to assess the short-term clinical efficacy of GON anaesthetic blocks in chronic migraine (CM) and to analyse their effect on pressure pain thresholds (PPTs) in different territories. Participants and methods The study was designed as a double-blind, randomised, placebo-controlled clinical trial. Thirty-six women with CM were treated either with bilateral GON block with bupivacaine 0.5%... περισσότερα »
Short-term effects of greater occipital nerve blocks in chronic migraine: A double-blind, randomised, placebo-controlled clinical trial
Background Greater occipital nerve (GON) blocks are widely used for the treatment of headaches, but quality evidence regarding their efficacy is scarce. Objective The objective of this article is to assess the short-term clinical efficacy of GON anaesthetic blocks in chronic migraine (CM) and to analyse their effect on pressure pain thresholds (PPTs) in different territories. Participants and methods The study was designed as a double-blind, randomised, placebo-controlled clinical trial. Thirty-six women with CM were treated either with bilateral GON block with bupivacaine 0.5%... περισσότερα »
MT3-MMP down-regulation promotes tumorigenesis and correlates to poor prognosis in esophageal squamous cell carcinoma
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract The membrane-type matrix metalloproteinases (MT-MMPs) play an important role in degrading the extracellular matrix (ECM) and facilitating protease-dependent tumor progression and invasion. Here, we report that unlike MT1-MMP, MT3-MMP was down-regulated in esophageal squamous cell carcinoma (ESCC) as detected by real-time PCR (qPCR), Western blot analysis, and immunohistochemistry (IHC). Down-regulation of MT3-MMP was observed […]
Downregulation of miR-133b predict progression and poor prognosis in patients with urothelial carcinoma of bladder
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract We found microRNA-133b (miR-133b) was downregulated in urothelial carcinoma of the bladder (UCB) tissues, and it could inhibit the proliferation and induce apoptosis in UCB cells. Consequently, we intend to explore the clinical significance of miR-133b in UCB patients. Expression of miR-133b in 146 UCB specimens and matched adjacent non-neoplastic bladder tissues were measured […]
Higher preoperative serum levels of PD-L1 and B7-H4 are associated with invasive and metastatic potential and predic table for poor response to VEGF-targeted therapy and unfavorable prognosis of renal cell carcinoma
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Renal cell carcinoma (RCC) is an immunogenic and proangiogenic cancer. Although antivascular endothelial growth factor (VEGF) therapies achieve impressive responses in some patients, many tumors eventually develop resistance to such therapy. The B7 family molecules such as CTLA-4, PD-1, and PD-L1 are pivotal players in immune checkpoints that positively or negatively regulate various immune […]
Thrombolytic Action of Apixaban on Intra-atrial Thrombus Developed after Previous Treatment with Warfarin: A Case Report
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/25Sbaew via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Objective It is well known that total cholesterol becomes less of a risk factor or not at all for all-cause and cardiovascular (CV) mortality with increasing age, but as little is known as to whether low-density lipoprotein cholesterol (LDL-C), one component of total cholesterol, is associated with mortality in the elderly, we decided to investigate […]
Idiopathic Inflammatory Myopathies: An update
2016-06-12T18-56-49Z *Source:* Journal of Interdisciplinary Histopathology Bulent KURT, Serdar TASDEMIR, Ertugrul CELIK, Kemal INAN. Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of disease with complex clinical features. It has been sub-classified as: (1) Dermatomyositis, (2) Polymyositis, and (3) Inclusion body myositis (IBM). Nowadays, there are some studies in literature suggest necrotizing autoimmune myopathy and immune-mediated necrotizing myopathy should also be added to this group of disease. There is a debate in the diagnosis of IIMs and up until now, abo... περισσότερα »
20Q: Pediatric Vestibular Disorders and the Role of the Audiologist
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
1. Pediatric assessment of dizziness? That’s something new for me. It’s new for a lot of us, but truth be told, there has never been a more exciting time to be in this area of Audiology. New research in pediatric vestibular assessment and management has opened our eyes to the developmental consequences of balance impairments. […]
20Q: Pediatric Vestibular Disorders and the Role of the Audiologist
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
1. Pediatric assessment of dizziness? That’s something new for me. It’s new for a lot of us, but truth be told, there has never been a more exciting time to be in this area of Audiology. New research in pediatric vestibular assessment and management has opened our eyes to the developmental consequences of balance impairments. […]
Evidence for the founder effect of a novel ACVRL1 splice-site mutation in Hungarian hereditary hemorrhagic telangiectasia families
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
from Genetics via xlomafota13 on Inoreader http://ift.tt/233ALvZ via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1UpmOGD via IFTTT
20Q: Pediatric Vestibular Disorders and the Role of the Audiologist
1. Pediatric assessment of dizziness? That's something new for me. It's new for a lot of us, but truth be told, there has never been a more exciting time to be in this area of Audiology. New research in pediatric vestibular assessment and management has opened our eyes to the developmental consequences of balance impairments. 2. You say "developmental"—I remember something about the vestibular system having several end organs? Right you are! In fact, there are five organs in the peripheral vestibular system with each one serving a different purpose. These five organs (three semici... περισσότερα »
20Q: Pediatric Vestibular Disorders and the Role of the Audiologist
1. Pediatric assessment of dizziness? That's something new for me. It's new for a lot of us, but truth be told, there has never been a more exciting time to be in this area of Audiology. New research in pediatric vestibular assessment and management has opened our eyes to the developmental consequences of balance impairments. 2. You say "developmental"—I remember something about the vestibular system having several end organs? Right you are! In fact, there are five organs in the peripheral vestibular system with each one serving a different purpose. These five organs (three semici... περισσότερα »
Adrenal, metabolic and cardio-renal dysfunction develops after pregnancy in rats born small or stressed by physiological measurements during pregnancy
Key points - Women born small are at an increased risk of developing pregnancy complications. Stress may further increase a woman's likelihood for an adverse pregnancy. - Adverse pregnancy adaptations can lead to long-term diseases even after her pregnancy. - The current study investigated the effects of stress during pregnancy on the long-term adrenal, metabolic and cardio-renal health of female rats that were born small. - Stress programmed increased adrenal *Mc2r* gene expression, a higher insulin secretory response to glucose during intraperitoneal g... περισσότερα »
Evidence for the founder effect of a novel ACVRL1 splice-site mutation in Hungarian hereditary hemorrhagic telangiectasia families
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 3 ώρες
[image: Thumbnail image of graphical abstract] from Genetics via xlomafota13 on Inoreader http://ift.tt/233ALvZ via IFTTT
Adrenal, metabolic and cardio-renal dysfunction develops after pregnancy in rats born small or stressed by physiological measurements during pregnancy
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 3 ώρες
Key points Women born small are at an increased risk of developing pregnancy complications. Stress may further increase a woman’s likelihood for an adverse pregnancy. Adverse pregnancy adaptations can lead to long-term diseases even after her pregnancy. The current study investigated the effects of stress during pregnancy on the long-term adrenal, metabolic and cardio-renal health […]
Άτυπο πάρκινσον και διαταραχές της ούρησης
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 3 ώρες
Ένα πάρα πολύ μεγάλο πρόβλημα στο άτυπο πάρκινσον και ιδιαίτερα στην ατροφία πολλαπλών συστημάτων είναι η εμφάνιση διαταραχών της ούρησης ή με τη μορφή επιτακτικής ούρησης ακόμα και στη σκέψη ότι πρέπει να πάει κάποιος στην τουαλέτα ή με ελαφριά ακράτεια η οποία επιβάλει πολλές φορές την εφαρμογή προστασίας (καθετήρας, πάνες ακράτειας). from #ORL-Sfakianakis via […]
Άτυπο πάρκινσον και διαταραχές αρτηριακής πίεσης
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 3 ώρες
Οι διαταραχές της αρτηριακής πίεσης στο άτυπο πάρκινσον είναι πάρα πολύ ισχυρές και είναι μάλιστα το κύριο χαρακτηριστικό της ατροφίας πολλαπλών συστημάτων η οποία σαν κλινική εικόνα κυριαρχεί σ’ αυτές τις καταστάσεις. from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1UMtqdM via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1rkByuG via IFTTT
Άτυπο πάρκινσον και αμιμία
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 3 ώρες
Γενικά στις περισσότερες μορφές παρκινσονισμού παρατηρείται μία σαφώς ελαττωμένη ικανότητα της μιμητικής έκφρασης του προσώπου. from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1Yme99q via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1tqM71c via IFTTT
Ατροφία πολλαπλών συστημάτων και διαταραχές ισορροπίας
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 3 ώρες
Οι διαταραχές της ισορροπίας είναι το κύριο χαρακτηριστικό στην ατροφία πολλαπλών συστημάτων, ιδιαίτερα σ΄ εκείνες τις περιπτώσεις που αυτή η μορφή της ατροφίας προσβάλει κυρίως και τις παρεγκεφαλιδικές δομές. from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1UMt4Uv via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1rkCoHN via IFTTT
