Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
*Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.* Proc Natl Acad Sci U S A. 2016 May 9; Authors: Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF Abstract The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+T1R3, encoded by Tas1r2 and Tas1r3 genes). However, in the absence of T1R2+T1R3 (e.g., in Tas1r3 KO mice), animals still respond to sugars, argui... περισσότερα »
Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.* Chem Senses. 2015 Nov;40(9):605-8 Authors: Brion M, de Timary P, Vander Stappen C, Guettat L, Lecomte B, Rombaux P, Maurage P Abstract Chemosensory (olfaction-taste) dysfunctions are considered as reliable biomarkers in many neurological and psychiatric states. However, experimental measures of chemosensory abilities are lacking in alcohol-dependence (AD) and Korsakoff Syndrome (KS, a neurological complication of ... περισσότερα »
Acoustic shadows help gleaning bats find prey, but may be defeated by prey acoustic camouflage on rough surfaces.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
[image: http:--cdn.elifesciences.org-images-elif] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Acoustic shadows help gleaning bats find prey, but may be defeated by prey acoustic camouflage on rough surfaces.* Elife. 2015;4 Authors: Clare EL, Holderied MW Abstract Perceptual abilities of animals, like echolocating bats, are difficult to study because they challenge our understanding of non-visual senses. We used novel acoustic tomography to convert echoes into visual representations and compare these cues to traditional echo measurements. We provide a new hypothesis f...περισσότερα »
Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
*Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.* Proc Natl Acad Sci U S A. 2016 May 9; Authors: Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF Abstract The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+T1R3, encoded by Tas1r2 and Tas1r3 genes). However, in the absence of T1R2+T1R3 (e.g., in Tas1r3 KO mice), animals still respond to sugars, argui... περισσότερα »
The Insect Chemoreceptor Superfamily Is Ancient in Animals.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *The Insect Chemoreceptor Superfamily Is Ancient in Animals.* Chem Senses. 2015 Nov;40(9):609-14 Authors: Robertson HM Abstract The insect chemoreceptor superfamily consists of 2 gene families, the highly diverse gustatory receptors (GRs) found in all arthropods with sequenced genomes and the odorant receptors that evolved from a GR lineage and have been found only in insects to date. Here, I describe relatives of the insect chemoreceptor superfamily, specifically the basal GR family, in diverse other animals, sho... περισσότερα »
Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.* Chem Senses. 2015 Nov;40(9):605-8 Authors: Brion M, de Timary P, Vander Stappen C, Guettat L, Lecomte B, Rombaux P, Maurage P Abstract Chemosensory (olfaction-taste) dysfunctions are considered as reliable biomarkers in many neurological and psychiatric states. However, experimental measures of chemosensory abilities are lacking in alcohol-dependence (AD) and Korsakoff Syndrome (KS, a neurological complication of ... περισσότερα »
Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
*Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.* Proc Natl Acad Sci U S A. 2016 May 9; Authors: Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF Abstract The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+T1R3, encoded by Tas1r2 and Tas1r3 genes). However, in the absence of T1R2+T1R3 (e.g., in Tas1r3 KO mice), animals still respond to sugars, argui... περισσότερα »
The Parkinson Disease Mitochondrial Hypothesis: Where Are We at?
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
Parkinson's disease is a common, adult-onset neurodegenerative disorder whose pathogenesis is still under intense investigation. Substantial evidence from postmortem human brain tissue, genetic- and toxin-induced animal and cellular models indicates that mitochondrial dysfunction plays a central role in the pathophysiology of the disease. This review discusses our current understanding of Parkinson's disease–related mitochondrial dysfunction, including bioenergetic defects, mitochondrial DNA alterations, altered mitochondrial dynamics, activation of mitochondrial-dependent program... περισσότερα »
Treatment of oral dysplasia with 5% imiquimod cream: short communication
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 8 δευτερόλεπτα
Publication date: Available online 10 May 2016 *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): R. Mullins, M. Ansell, S. Laverick We report what we think is the first treatment of oral dysplasia with 5% imiquimod cream. A 60-year-old man presented with varying degrees of dysplasia on the soft palate. A cover plate was fabricated and the patient was prescribed 5% imiquimod cream, a topical imunomodulator, for six weeks. The lesion improved and histological examination of an incisional biopsy found no features of dysplasia. This case highlights the efficacy of im... περισσότερα »
Loneliness among People with Spinal Cord Injury: Exploring the Psychometric Properties of the 3-item Loneliness Scale
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 11 δευτερόλεπτα
Publication date: Available online 11 May 2016 *Source:*Archives of Physical Medicine and Rehabilitation Author(s): Susan Robinson-Whelen, Heather B. Taylor, Michelle Feltz, Megan Whelen ObjectiveTo examine a measure of loneliness and its correlates in people with spinal cord injury (SCI) to enhance our understanding of loneliness, which has received limited scientific study in the context of SCI, and to conduct preliminary analyses of the reliability and validity of the measure, including an evaluation of the unique impact of loneliness on psychological health.DesignCross-sectional... περισσότερα »
Rehabilitation outcomes after inpatient rehabilitation for lower extremity amputations in patients with diabetes
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 11 δευτερόλεπτα
Publication date: Available online 11 May 2016 *Source:*Archives of Physical Medicine and Rehabilitation Author(s): Kavita Venkataraman, Ngan Phoon Fong, Kin Ming Chan, Boon Yeow Tan, Edward Menon, Chye Hua Ee, Kok Keng Lee, Gerald Choon-Huat Koh ObjectiveTo identify factors associated with functional gain, discharge destination and long-term survival following inpatient rehabilitation in patients with lower extremity amputation and diabetes.DesignRetrospective medical records reviewSettingAll community hospitals in Singapore (n=4) between 1996 and 2005Participants256 patients with d... περισσότερα »
La enfermedad de tiroides en el paciente de edad avanzada
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
DEFINICIÓN : ¿Qué significan los siguientes servicios por PACIENTES edad de 60 años tienen en común ? 1. *Una mujer de 72 años de edad con ” aleteo del corazón ” y molestias en el pecho vaga en las escaleras que suben* 2. *Un hombre de 80 años de edad con estreñimiento severo que se duerme a menudo* 3. *Una mujer de 65 años que ha perdido fuerza en sus piernas , causando dificultad para subir escaleras , ella ha perdido recientemente 15 libras , a pesar de un muy buen apetito* 4. *Una mujer de 75 años que ha desarrollado dificultad para tragar y tos sec... περισσότερα »
HABP2 Gene Mutations Do Not Cause Familial or Sporadic Non-Medullary Thyroid Cancer
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
in a Highly Inbred Middle Eastern Population *To cite this article:Alzahrani Ali S., Murugan Avaniyapuram Kannan, Qasem Ebtesam, and Al-Hindi Hindi. Thyroid. April 2016, 26(5): 667-671. doi:10.1089/thy.2015.0537* *- Full Text HTML - Full Text PDF (213.2 KB) - Full Text PDF with Links (165.2 KB)* Navigate ArticleTop of pageAuthor information <<ABSTRACTIntroductionPatients and MethodsResultsDiscussionAuthor Disclosure Stateme...ReferencesAuthor information *Ali S. Alzahrani,1,2,3 Avaniyapuram Kannan Murugan,1 Ebtesam Qasem,1 and Hindi Al-Hindi4* *1Department of Molecular Onco... περισσότερα »
Genomic Alterations of Anaplastic Thyroid Carcinoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Detected by Targeted Massive Parallel Sequencing in a *BRAFV600E* Mutation-Prevalent Area *To cite this article:Jeon Min Ji, Chun Sung-Min, Kim Deokhoon, Kwon Hyemi, Jang Eun Kyung, Kim Tae Yong, Kim Won Bae, Shong Young Kee, Jang Se Jin, Song Dong Eun, and Kim Won Gu. Thyroid. April 2016, 26(5): 683-690. doi:10.1089/thy.2015.0506.* *- Full Text HTML - Full Text PDF (351.4 KB) - Full Text PDF with Links (250.9 KB)* Navigate ArticleTop of pageAuthor information <<ABSTRACTIntroductionMaterials and MethodsResultsDiscussionAcknowledgmentsAuthor Disclosure Stateme... ReferencesA... περισσότερα »
Antithyroid Drug–Induced Agranulocytosis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Characteristics of Antithyroid Drug–Induced Agranulocytosis in Patients with Hyperthyroidism: A Retrospective Analysis of 114 Cases in a Single Institution in China Involving 9690 Patients Referred for Radioiodine Treatment Over 15 Years *To cite this article:Yang Jun, Zhu Yang-Jun, Zhong Ji-Jun, Zhang Jun, Weng Wan-Wen, Liu Zhen-Feng, Xu Qin, and Dong Meng-Jie. Thyroid. April 2016, 26(5): 627-633. doi:10.1089/thy.2015.0439.* *- Full Text HTML - Full Text PDF (242.5 KB) - Full Text PDF with Links (202 KB)* Navigate ArticleTop of pageAuthor information <<ABSTRACTIntroductionM... περισσότερα »
Contrast-Enhanced Multi-Detector CT (64 Channels) Protocol for Papillary Thyroid Carcinoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Feasibility Study of a Contrast-Enhanced Multi-Detector CT (64 Channels) Protocol for Papillary Thyroid Carcinoma: The Influence of Different Scan Delays on Tumor Conspicuity *To cite this article:Lee Young Hen, Seo Hyung Suk, Suh Sang-il, Ryoo Inseon, You Sung-Hye, Son Kyu Ri, Kwon Soon-Young, Son Gil Soo, and Yang Kyung-Sook. Thyroid. April 2016, 26(5): 726-733. doi:10.1089/thy.2015.0415.* *- Full Text HTML - Full Text PDF (412.9 KB) - Full Text PDF with Links (341.9 KB)* Navigate ArticleTop of pageAuthor information <<ABSTRACTIntroductionMethods ResultsDiscussionAuthor Dis... περισσότερα »
Severe Thyroid Dermopathy
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Response of a Patient with Severe Thyroid Dermopathy to Combined Multipoint Subcutaneous Injection of Glucocorticoids and Local Excision *To cite this article:Huang Yingshi, Wei Chiju, Ma Shuhua, Fu Yucai, and Xu Wencan. Thyroid. April 2016, 26(5): 753-755. doi:10.1089/thy.2015.0134.* *- Full Text HTML - Full Text PDF (294 KB) - Full Text PDF with Links (162.9 KB)* Navigate ArticleTop of pageAuthor information <<AcknowledgmentsAuthor Disclosure Stateme...ReferencesAuthor information *Yingshi Huang,1 Chiju Wei,2 Shuhua Ma,3 Yucai Fu,4 and Wencan Xu5* *1Health Care Center, First...περισσότερα »
A Genomic Alternative to Identify Medullary Thyroid Cancer Preoperatively in Thyroid Nodules with Indeterminate Cytology
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
*To cite this article:* *Kloos Richard T., Monroe Robert J., Traweek S. Thomas, Lanman Richard B., and Kennedy Giulia C.. Thyroid. April 2016, ahead of print. doi:10.1089/thy.2016.0001.* *- Full Text HTML - Full Text PDF (438.5 KB) - Full Text PDF with Links (331.8 KB)* Navigate ArticleTop of pageAuthor information <<ABSTRACTIntroductionMaterials and MethodsResultsDiscussionAcknowledgmentsAuthor Disclosure Stateme... ReferencesAuthor information *Richard T. Kloos,1 Robert J. Monroe,2 S. Thomas Traweek,3 Richard B. Lanman,1† and Giulia C. Kennedy4* *1Department of Medical Affai...περισσότερα »
American Thyroid Association
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
FREE ACCESS through May 20, 2016. Read Now: Characteristics of Antithyroid Drug–Induced Agranulocytosis in Patients with Hyperthyroidism: A Retrospective Analysis of 114 Cases in a Single Institution in China Involving 9690 Patients Referred for Radioiodine Treatment Over 15 Years Jun Yang, Yang-Jun Zhu, Ji-Jun Zhong, Jun Zhang, Wan-Wen Weng, Zhen-Feng Liu, Qin Xu, Meng-Jie Dong HABP2 Gene Mutations Do Not Cause Familial or Sporadic Non-Medullary Thyroid Cancer in a Highly Inbred Middle Eastern Population Ali S. Alzahrani, Avaniyapuram Kannan Murugan, Ebtesam Qasem, Hindi Al-Hindi Ge... περισσότερα »
Subtotal petrosectomy
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Subtotal petrosectomy and Codacs™: new possibilities in ears with chronic infection: AbstractSubtotal petrosectomy combined with obliteration of the tympanomastoid is a standard procedure to treat temporal bones in patients with radical cavity and chronic infections. Currently, patients with profound-to-severe sensorineural hearing loss are often fitted with cochlear implants. In the case of profound mixed hearing loss, active middle ear implants have been used successfully. The new Codacs™ system provides an effective treatment for patients with severe-to-profound mixed hearing l... περισσότερα »
Thyroglossal duct cyst excision with hyoid bone preservation
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Thyroglossal duct cyst excision with hyoid bone preservation: AbstractThe objective of this study is to assess complete removal of the thyroglossal duct cyst (TGDC) and its tract(s) to the base of the tongue with sparing of the hyoid bone. This is a prospective cohort study. Tertiary hospital (Zagazig university hospital). This prospective study was carried out on 21 patients who had been diagnosed preoperatively as TGDC or fistula. All patients were managed by dissection and removal of the TGDC and its tract(s) to the base of the tongue with sparing of the hyoid bone. The study wa... περισσότερα »
Testing in early recovery from vestibular deafferentation
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Compensatory saccades benefit from prediction during head impulse testing in early recovery from vestibular deafferentation: AbstractThe head impulse test (HIT) can identify a deficient vestibulo-ocular reflex (VOR) by the compensatory saccade (CS) generated once the head stops moving. The inward HIT is considered safer than the outward HIT, yet might have an oculomotor advantage given that the subject would presumably know the direction of head rotation. Here, we compare CS latencies following inward (presumed predictable) and outward (more unpredictable) HITs after acute unilater... περισσότερα »
Compensatory saccades benefit from prediction during head impulse testing
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
in early recovery from vestibular deafferentation: AbstractThe head impulse test (HIT) can identify a deficient vestibulo-ocular reflex (VOR) by the compensatory saccade (CS) generated once the head stops moving. The inward HIT is considered safer than the outward HIT, yet might have an oculomotor advantage given that the subject would presumably know the direction of head rotation. Here, we compare CS latencies following inward (presumed predictable) and outward (more unpredictable) HITs after acute unilateral vestibular nerve deafferentation. Seven patients received inward and o... περισσότερα »
Endocavitary brachytherapy in patients with cancers of the nasal cavity, sinonasal region and nasopharynx
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Customized individual applicators for AbstractBrachytherapy has become an established therapeutic regimen for primary, persistent, recurrent and metastatic tumour disease in the head and neck region. This study presents the authors’ preliminary experience with intracavitary brachytherapy by means of an individual silicone applicator in the treatment of patients with nasal, sinonasal, orbital and nasopharyngeal cancer. Between January 2001 and January 2013, twenty patients with cancer of the nasal cavity, the paranasal sinuses and nasopharynx underwent surgery and intracavitary brac... περισσότερα »
Stability of allergen extracts to establish expiration dating
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Update: Purpose of review: The article reviews studies pertaining to US manufactured allergen extract stability that contribute to guidance for expiration dating for bulk concentrates, diluted patient testing and treatment vials, and adjustments following elevated temperature excursions. Recent findings: Studies on allergen stability were completed to satisfy the Food and Drug Administration requirements supporting labeled expiration dating for standardized short ragweed, dust mites, cat, grass, and venom extracts and are not published. These studies demonstrated the stability enha... περισσότερα »
Allergy and laryngeal disorders
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Allergy and laryngeal disorders: Purpose of review: This article reviews recent literature on the topic of allergic laryngitis. There has been sustained interest over the past 15 years and epidemiological and experimental studies have led to a clearer description of the nature of the condition and its clinical expression. Recent findings: Recent studies have suggested an epidemiological association between the presence of allergy and concurrent laryngeal symptoms and objective signs. Both population-based studies and smaller investigations have shown a significant relationship betwe... περισσότερα »
Food allergy in children
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Current concepts: diagnosis and management of food allergy in children: Purpose of review: Advances in the prevention and treatment of food allergy have been published in the last few years and are placed in context using a review format. Recent findings: Preventing food allergy has been studied for years with questions of whether avoidance or exposure was a better strategy. Recent research has suggested that peanut allergy can be substantially reduced in high-risk infants through intentional oral exposure. For children with food allergy, the primary treatment remains avoidance, but... περισσότερα »
Allergy immunotherapy in the treatment of asthma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
The role of Purpose of review: Asthma and allergic rhinitis are two of the most widespread chronic medical conditions. Asthma, a condition which encompasses chronic inflammation of the lower airway resulting in expiratory obstruction, may represent an end phase along the allergic disease spectrum ultimately stemming initially from nasal allergic rhinitis and bronchial hyper-reactivity. The purpose of this review was to evaluate the available published literature over the past 12 months regarding the role of allergy immunotherapy in the treatment of asthma. Recent findings: Recent ... περισσότερα »
Secondhand smoke and rhinitis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Secondhand smoke and rhinitis: Purpose of review: The article reviews the most recent literature on the association between secondhand tobacco smoke exposure and rhinitis. The discussion will focus on the biologic links between tobacco exposure and rhinitis symptoms, evaluating this relationship in different populations. Recent findings: Significant associations between tobacco smoke exposure and rhinitis symptoms have been identified in US children and adults. This association is not just a US public health concern, as similar analyses have also recently been performed in other pop... περισσότερα »
The prevention and rehabilitation of dysphagia in HNC
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Research into the prevention and rehabilitation of dysphagia in head and neck cancer: a UK perspective: Purpose of review: There is an increasing recognition of dysphagia as a frequent, often severe and chronic side-effect of head and neck cancer treatment. There has been a global increase in the number of head and neck cancer survivors, increasing the urgency of finding ways to best manage swallowing difficulties. Recent findings: There are several research studies investigating strategies and developing interventions to prevent and treat this debilitating condition. The United K... περισσότερα »
Allergy immunotherapy
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
New advances in Purpose of review: The present article reviews the literature on new methods for administering specific immunotherapy for the treatment of immunoglobulin E-mediated hypersensitivity to airborne and food allergens. The discussion will focus on allergen modifications, and new routes for delivering proteins to allergen-presenting cells. Recent findings: Modified allergens address the issues of supply and standardization, but also have the potential to enhance the allergenicity of the protein, while decreasing the risk of producing severe reactions. The use of immunost... περισσότερα »
Spasmodic dysphonia
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Review of differential diagnosis and management of Purpose of review: The recent literature on spasmodic dysphonia is reviewed with regard to pathogenesis, differential diagnosis, treatment options, audits, and current methods of management. Recent findings: Advances in technology have enabled clinicians to better understand the connection between brain and laryngeal function and dysfunction. Refinements in imaging and genetic investigation techniques have led to advances in the understanding of the underlying mechanism of this neurolaryngeal disorder. Development of diagnostic ass... περισσότερα »
Vocal fold paresis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
a review of clinical presentation, differential diagnosis, and prognostic indicators: [image: image] Purpose of review: Vocal fold paresis is a complex, controversial, and unique clinical entity. Guidance in assessing and evaluating these patients is provided in this comprehensive review of the current literature discussing the varying clinical presentation, the broad differential and general prognosis. Recent findings: Patients with vocal fold paresis can present with elements of hyperfunction, which can often mask an underlying paresis. As such, repetitive phonatory tasks and vi...περισσότερα »
Epidemiology of asthma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Epidemiology of asthma: Purpose of review: This article reports the findings of recently published research articles and Centers for Disease Control (CDC) data on the epidemiology of asthma. Numerous otolaryngologic diseases are associated with asthma, such as allergic rhinitis, chronic rhinosinusitis, and obstructive sleep apnea. In addition, asthma causes a significant health burden and its prevalence is increasing. Recent findings: Currently, 8.4% of persons in the United States have asthma as compared with 4.3% of the population worldwide, and both numbers are on the rise. The... περισσότερα »
Cough reflex testing to guide dysphagia management in the postsurgical adult head and neck patient population
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
A service evaluation of Purpose of review: The article reviews recent literature supporting the use of cough reflex testing (CRT), and outlines a service evaluation of CRT conducted with postsurgical head and neck cancer patients. There is a growing evidence base to support the use of CRT in dysphagia management to establish laryngeal sensation and screen for silent aspiration; however, there is a lack of evidence relating to using CRT within the head and neck population. Recent findings: Over a 3-month period, inpatients on an ear, nose and throat/maxillofacial ward underwent CRT... περισσότερα »
Providing allergen immunotherapy in the office
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Safety considerations in Purpose of review: This review highlights the risks of allergy immunotherapy, methods to improve the quality and safety of allergy treatment, the current status of allergy quality metrics, and the future of quality measurement. In the current healthcare environment, the emphasis on outcomes measurement is increasing, and providers must be better equipped in the development, measurement, and reporting of safety and quality measures. Recent findings: Immunotherapy offers the only potential cure for allergic disease and asthma. Although well tolerated and e... περισσότερα »
Inter-rater reliability of h-index scores calculated by Web of Science and Scopus for clinical epidemiology scientists
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 14 δευτερόλεπτα
Abstract Objective We investigated the inter-rater reliability of Web of Science (WoS) and Scopus when calculating the h-index of 25 senior scientists in the Clinical Epidemiology Program of the Ottawa Hospital Research Institute. Materials and methods Bibliometric information and the h-indices for the subjects were computed by four raters using the automatic calculators in WoS… Continue reading Inter-rater reliability of h-index scores calculated by Web of Science and Scopus for clinical epidemiology scientists
A Genomic Alternative to Identify Medullary Thyroid Cancer Preoperatively in Thyroid Nodules with Indeterminate Cytology
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 14 δευτερόλεπτα
To cite this article: Kloos Richard T., Monroe Robert J., Traweek S. Thomas, Lanman Richard B., and Kennedy Giulia C.. Thyroid. April 2016, ahead of print. doi:10.1089/thy.2016.0001. Full Text HTML Full Text PDF (438.5 KB) Full Text PDF with Links (331.8 KB) Navigate ArticleTop of pageAuthor information <<ABSTRACTIntroductionMaterials and MethodsResultsDiscussionAcknowledgmentsAuthor Disclosure Stateme…References Author information Richard… Continue reading A Genomic Alternative to Identify Medullary Thyroid Cancer Preoperatively in Thyroid Nodules with Indeterminate Cytology
Osteopathia striata with cranial sclerosis (OSCS): review of the literature and case report demonstrating challenges of spinal fusion after trauma
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 14 δευτερόλεπτα
Abstract Osteopathia striata with cranial sclerosis (OSCS) is a rare but well-described pathology characterized by abnormalities in bone deposition in the axial and cranial skeleton as well as other abnormalities and associated deficits. These skeletal abnormalities can lead to significant intra-operative challenges for the surgeon and influence outcomes for the patient. In this report, we… Continue reading Osteopathia striata with cranial sclerosis (OSCS): review of the literature and case report demonstrating challenges of spinal fusion after trauma
Barriers to the use of the library service amongst clinical staff in an acute hospital setting: an evaluation
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 14 δευτερόλεπτα
Abstract This article reports on research into the reasons why clinical staff in an acute hospital may be reluctant to use library services. The research was conducted by Gaynor Thomas at the Prince Philip Hospital in Llanelli in Wales as part of the dissertation she completed for an MSc in Economics. She graduated in July… Continue reading Barriers to the use of the library service amongst clinical staff in an acute hospital setting: an evaluation
Regenerative implantable medical devices: an overview
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 14 δευτερόλεπτα
Abstract Objectives To conduct a bibliometric evaluation and trend prediction of English literature on animal-derived regenerative implantable medical devices based on tissue engineering technology. Methods Data identified by a search strategy with eleven combinations of keywords before 1 January, 2014 were downloaded from eight databases on 25 November, 2014. The study analysed publication year, journal… Continue reading Regenerative implantable medical devices: an overview
Schmerz – ein vernachlässigtes neurologisches Thema
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 14 δευτερόλεπτα
Zusammenfassung Chronische Schmerzen stellen eine große Herausforderung dar und es ist von einer steten Zunahme der Patientenzahlen auszugehen. Die Pathophysiologie chronischer Schmerzen wird in den letzten Jahren zunehmend besser verstanden, wobei neurologische Schmerzforscher dabei einen großen Anteil hatten. Bei chronischen Schmerzen kommt es zu substanziellen plastischen Veränderungen des gesamten Nervensystems, d. h. neurologisches Wissen wird hier… Continue reading Schmerz – ein vernachlässigtes neurologisches Thema
Regeneration of Liver Function Capacity After Partial Liver Resection is Impaired in Case of Postoperative Bile Leakage
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 14 δευτερόλεπτα
Abstract Background Postoperative bile leakage (PBL) is a major surgical complication after partial liver resection resulting in increased perioperative morbidity and mortality. Previous experimental studies have shown an adverse effect on functional liver regeneration, but there are still no data available concerning these effects in humans. Materials and methods A retrospective matched pair analysis was… Continue reading Regeneration of Liver Function Capacity After Partial Liver Resection is Impaired in Case of Postoperative Bile Leakage
A diffuse traumatic neuroma in the palate: a case report
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 14 δευτερόλεπτα
A traumatic neuroma is not a true neoplasm but a reactive proliferation of neural tissue that commonly occurs after the transection or damage of a nerve bundle. Traumatic neuromas are rare in the oral region a… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1TEI868 via IFTTT
Brennpunkt Notaufnahme
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 14 δευτερόλεπτα
Zusammenfassung Die Zahl der in deutschen Notaufnahmen behandelten Patienten ist in den letzten Jahren auf ca. 20 Mio. Patienten angestiegen. Diese Steigerung betrifft auch die dort behandelten neurologischen Symptome und Erkrankungen, die bei etwa 20 % der Notaufnahmepatienten vorliegen. Neben dringlich zu behandelnden Patienten mit Schlaganfällen oder entzündlichen oder degenerativen Erkrankungen des Zentralnervensystems und Erkrankungen des… Continue reading Brennpunkt Notaufnahme
Bioelectrical phase angle and psoriasis: a novel association with psoriasis severity, quality of life and metabolic syndrome
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 14 δευτερόλεπτα
Obesity, metabolic syndrome (MetS), and psoriasis, largely driven by environmental factors, show multiple bidirectional associations, with important metabolic implications in psoriatic patients. Besides body m… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1WpczUZ via IFTTT
The Effect of False Vocal Folds on Laryngeal Flow Resistance in a Tubular Three-dimensional Computational Laryngeal Model
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 19 δευτερόλεπτα
Publication date: Available online 10 May 2016 *Source:*Journal of Voice Author(s): Qian Xue, Xudong Zheng ObjectiveThe current study used a three-dimensional (3D) computational laryngeal model to investigate the effect of false vocal folds (FVFs) on laryngeal flow resistance.MethodA 3D, tubular shaped computational laryngeal model was designed with a high level of realism with respect to the human laryngeal anatomy. Two cases, one with the FVFs and the other without the FVFs, were created in the numerical simulation to compare the laryngeal flow behaviors.Results and ConclusionThe ... περισσότερα »
Investigation of the Immediate Effects of Humming on Vocal Fold Vibration Irregularity Using Electroglottography and High-speed Laryngoscopy in Patients With Organic Voice Disorders
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 19 δευτερόλεπτα
Publication date: Available online 10 May 2016 *Source:*Journal of Voice Author(s): Carien Vlot, Makoto Ogawa, Kiyohito Hosokawa, Toshihiko Iwahashi, Chieri Kato, Hidenori Inohara ObjectivesThe study aimed to investigate whether humming can immediately improve the regularity of vocal fold vibration on electroglottography (EGG) and laryngeal high-speed digital imaging (HSDI) in patients with organic dysphonia (OD).MethodsIn a series of 49 dysphonic patients who were diagnosed to have benign mass lesions in the vocal folds and an equal number of non-dysphonic speakers, perturbation pa... περισσότερα »
Cichorium intybus root extract: A "vitamin D-like" active ingredient to improve skin barrier function.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*Cichorium intybus root extract: A "vitamin D-like" active ingredient to improve skin barrier function.* J Dermatolog Treat. 2016 May 10;:1-4 Authors: Maia Campos PM, G Mercurio D, O Melo M, Closs-Gonthier B Abstract During the aging process, the human skin suffers many alterations including dryness, skin barrier function damage. The skin barrier function is important to the prevention of skin alterations and maintenance of homeostasis. So, the objective of this study was to assess the clinical efficacy on skin barrier function of Cichorium intybus root extract in cosmetic formul... περισσότερα »
Long-term results of rituximab-intravenous immunoglobulin combination therapy in patients with epidermolysis bullosa acquisita resistant to conventional therapy.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*Long-term results of rituximab-intravenous immunoglobulin combination therapy in patients with epidermolysis bullosa acquisita resistant to conventional therapy.* J Dermatolog Treat. 2016 May 10;:1-5 Authors: Oktem A, Akay BN, Boyvat A, Kundakci N, Erdem C, Bostancı S, Sanli H, Kocyigit P Abstract BACKGROUND: Epidermolysis bullosa acquisita (EBA) is a rare subepidermal bullous disease. Long-term remission in this disease is difficult using current treatments, unlike that in patients with other autoimmune bullous diseases. OBJECTIVE: We retrospectively evaluated the effectiveness... περισσότερα »
Adherence to topical therapies in actinic keratosis: A literature review.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*Adherence to topical therapies in actinic keratosis: A literature review.* J Dermatolog Treat. 2016 May 10;:1-8 Authors: Foley P, Stockfleth E, Peris K, Basset-Seguin N, Cerio R, Antonio Sanches J, Guillen C, Farrington E, Lebwohl M Abstract BACKGROUND: Actinic keratosis (AK) is a common skin condition, for which topical therapies are frequently prescribed. This review summarises current understanding of patient adherence and persistence to topical AK treatment by identifying literature relating to measures of adherence and persistence and influencing factors. METHODS: A multi-da... περισσότερα »
Benefit-risk tradeoff preferences for chronic hand eczema treatments.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*Benefit-risk tradeoff preferences for chronic hand eczema treatments.* J Dermatolog Treat. 2016 May 10;:1-7 Authors: Hauber AB, Mohamed AF, Gonzalez JM, Otteson Fairchild A, Zelt SC, Graff O Abstract Hand eczema affects approximately 16% of the US population. The long-term prognosis is poor, and 5-7% experience severe chronic hand eczema (sCHE) that interferes with daily activities. Treatments for CHE may be ineffective or associated with adverse events (AEs) that may dissuade patients from pursuing or continuing treatment. For quantification of patient experiences and benefit-r... περισσότερα »
Oral hygiene grade and quality of life in children with chemotherapy-related oral mucositis: a randomized study on the impact of a fluoride toothpaste with salivary enzymes, essential oils, proteins and colostrum extract versus a fluoride toothpaste without menthol.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*Oral hygiene grade and quality of life in children with chemotherapy-related oral mucositis: a randomized study on the impact of a fluoride toothpaste with salivary enzymes, essential oils, proteins and colostrum extract versus a fluoride toothpaste without menthol.* Int J Dent Hyg. 2016 May 10; Authors: Bardellini E, Amadori F, Majorana A Abstract AIM: The aim of this study was to assess the impact of the use of a fluoride toothpaste (Bioxtra(®) , Biopharm, Milan, Italy) with salivary enzymes, essential oils, proteins and colostrum extract versus a fluoride toothpaste without m... περισσότερα »
Phase II trial of weekly Docetaxel, Zoledronic acid, and Celecoxib for castration-resistant prostate cancer.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*Phase II trial of weekly Docetaxel, Zoledronic acid, and Celecoxib for castration-resistant prostate cancer.* Invest New Drugs. 2016 May 10; Authors: Kattan J, Bachour M, Farhat F, El Rassy E, Assi T, Ghosn M Abstract Background Treatment options for patients with metastatic castration-resistance prostate cancer are unsatisfactory. Docetaxel monotherapy offers promising results with a tolerable toxicity profile. However, enhancing the clinical index of Docetaxel-based therapy remains the ultimate goal. Methods We conducted a phase II, open label, multinational prospective trial ... περισσότερα »
WITHDRAWN: Acyclovir for treating primary herpetic gingivostomatitis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *WITHDRAWN: Acyclovir for treating primary herpetic gingivostomatitis.* Cochrane Database Syst Rev. 2016;1:CD006700 Authors: Nasser M, Fedorowicz Z, Khoshnevisan MH, Shahiri Tabarestani M PMID: 26784280 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1rUFgeV via IFTTT
Pyoblepharitis Vegetans in Association With Pyodermatitis-Pyostomatitis Vegetans: Expanding the Spectrum of a Rare, Multisystem Disorder.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Pyoblepharitis Vegetans in Association With Pyodermatitis-Pyostomatitis Vegetans: Expanding the Spectrum of a Rare, Multisystem Disorder.* J Cutan Med Surg. 2016 Mar-Apr;20(2):163-5 Authors: Dupuis EC, Haber RM, Robertson LH Abstract BACKGROUND: Pyodermatitis-pyostomatitis vegetans (PDPSV) is a rare inflammatory disorder of the skin and oral mucosa that is commonly associated with inflammatory bowel disease (IBD). Ocular involvement is uncommon. OBJECTIVE: Given the association with IBD, it is important for derma... περισσότερα »
International Outcomes of the Boston Type I Keratoprosthesis in Stevens-Johnson Syndrome.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *International Outcomes of the Boston Type I Keratoprosthesis in Stevens-Johnson Syndrome.* Cornea. 2015 Nov;34(11):1387-94 Authors: Alexander JK, Basak SK, Padilla MD, Yu F, Aldave AJ Abstract PURPOSE: To determine the factors influencing outcomes of Boston type I keratoprosthesis implantation in Stevens-Johnson syndrome (SJS) and to compare the results with those of individuals without SJS. METHODS: This is a multicenter, retrospective, comparative consecutive case series of patients undergoing keratoprosthesis i... περισσότερα »
Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Maternal and Foetal Outcomes in Twenty-Two Consecutive Pregnant HIV Infected Women.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Maternal and Foetal Outcomes in Twenty-Two Consecutive Pregnant HIV Infected Women.* PLoS One. 2015;10(8):e0135501 Authors: Knight L, Todd G, Muloiwa R, Matjila M, Lehloenya RJ Abstract INTRODUCTION: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) form a spectrum of a rare and life-threatening cutaneous drug reaction. SJS/TEN in pregnancy poses largely unknown risk factors and outcomes for both the mother and fo...περισσότερα »
Simple and fast orotracheal intubation procedure in rats.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*Simple and fast orotracheal intubation procedure in rats.* Acta Biomed. 2016;87(1):13-15 Authors: Tomasello G, Damiani F, Cassata G, Palumbo VD, Sinagra E, Damiani P, Bruno A, Cicero L, Cupido F, Carini F, Lo Monte AI Abstract INTRODUCTION: Endotracheal intubation in the rat is difficult because of the extremely small size of anatomical structures (oral cavity, epiglottis and vocal cords), small inlet for an endotracheal tube and the lack of proper technical instruments. MATERIAL AND METHODS: In this study we used seventy rats weighting 400-500 g. The equipment needed for the int... περισσότερα »
A nationwide study on enlargement of the vestibular aqueduct in Japan.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*A nationwide study on enlargement of the vestibular aqueduct in Japan.* Auris Nasus Larynx. 2016 May 6; Authors: Noguchi Y, Fukuda S, Fukushima K, Gyo K, Hara A, Nakashima T, Ogawa K, Okamoto M, Sato H, Usami SI, Yamasoba T, Yokoyama T, Kitamura K Abstract OBJECTIVE: To document the clinical features and associated pure-tone audiometry data in patients with enlargement of the vestibular aqueduct (EVA), and to identify risk factors for fluctuating hearing loss (HL) and vertigo/dizziness in EVA patients. METHODS: In this nationwide survey in Japan, a first survey sheet was mailed t... περισσότερα »
Design, development and validation of a new laryngo-pharyngeal endoscopic esthesiometer and range-finder based on the assessment of air-pulse variability determinants.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*Design, development and validation of a new laryngo-pharyngeal endoscopic esthesiometer and range-finder based on the assessment of air-pulse variability determinants.* Biomed Eng Online. 2016;15(1):52 Authors: Giraldo-Cadavid LF, Agudelo-Otalora LM, Burguete J, Arbulu M, Moscoso WD, Martínez F, Ortiz AF, Diaz J, Pantoja JA, Rueda-Arango AF, Fernández S Abstract BACKGROUND: Laryngo-pharyngeal mechano-sensitivity (LPMS) is involved in dysphagia, sleep apnea, stroke, irritable larynx syndrome and cough hypersensitivity syndrome among other disorders. These conditions are associat... περισσότερα »
Anti EGFR therapy in the treatment of non-metastatic head and neck squamous cell carcinoma: The current evidence.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*Anti EGFR therapy in the treatment of non-metastatic head and neck squamous cell carcinoma: The current evidence.* J Egypt Natl Canc Inst. 2016 May 6; Authors: Benson R, Mallick S, Julka PK, Rath GK Abstract Head and neck squamous cell carcinoma (HNSCC) accounts for a large oncologic burden in the developing countries. In patients with locally advanced head and neck cancer multimodality treatment is warranted. Radiation therapy with concurrent chemotherapy has long been considered the standard for patients with disease involving the oropharynx, larynx and hypopharynx. However, a... περισσότερα »
Details of regional particle deposition and airflow structures in a realistic model of human tracheobronchial airways: two-phase flow simulation.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
*Details of regional particle deposition and airflow structures in a realistic model of human tracheobronchial airways: two-phase flow simulation.* Comput Biol Med. 2016 Apr 27;74:1-17 Authors: Rahimi-Gorji M, Gorji TB, Gorji-Bandpy M Abstract In the present investigation, detailed two-phase flow modeling of airflow, transport and deposition of micro-particles (1-10µm) in a realistic tracheobronchial airway geometry based on CT scan images under various breathing conditions (i.e. 10-60l/min) was considered. Lagrangian particle tracking has been used to investigate the particle de... περισσότερα »
Chondrosarcoma of the hyoid bone: a case report.
Alexandros G. SfakianakisστοHead and NeckΠριν από 23 δευτερόλεπτα
Related Articles *Chondrosarcoma of the hyoid bone: a case report.* Rom J Morphol Embryol. 2015;56(2 Suppl):811-6 Authors: Ciolofan MS, Ioniţă E, Ioniţă I, Mogoantă CA, Anghelina F, Enescu AŞ, Ciobîrcă DM, Osman A, Foarfă MC, Mateescu GO Abstract Chondrosarcoma is a malignancy of the mesenchymal tissue derived from transformed cells that produce the cartilage matrix. In the neck area, it represents less than 0.5% of malignant tumor pathology. Chondrosarcoma of the hyoid bone is extremely rare, only 20 cases having been published so far (PubMed 2014). We present the case of a 30-y... περισσότερα »
Schmerz – ein vernachlässigtes neurologisches Thema
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 23 δευτερόλεπτα
Zusammenfassung Chronische Schmerzen stellen eine große Herausforderung dar und es ist von einer steten Zunahme der Patientenzahlen auszugehen. Die Pathophysiologie chronischer Schmerzen wird in den letzten Jahren zunehmend besser verstanden, wobei neurologische Schmerzforscher dabei einen großen Anteil hatten. Bei chronischen Schmerzen kommt es zu substanziellen plastischen Veränderungen des gesamten Nervensystems, d. h. neurologisches Wissen wird hier explizit vom Behandler abverlangt. Dies kontrastiert leider mit der Versorgungssituation von Schmerzpatienten. Grundsätzlich exist... περισσότερα »
Regeneration of Liver Function Capacity After Partial Liver Resection is Impaired in Case of Postoperative Bile Leakage
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 23 δευτερόλεπτα
Abstract Background Postoperative bile leakage (PBL) is a major surgical complication after partial liver resection resulting in increased perioperative morbidity and mortality. Previous experimental studies have shown an adverse effect on functional liver regeneration, but there are still no data available concerning these effects in humans. Materials and methods A retrospective matched pair analysis was carried out comparing the postoperative course of 51 patients with PBL to 51 patients without PBL. The influence of PBL on actual liver function was determined by means of LiMAx... περισσότερα »
Brennpunkt Notaufnahme
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 23 δευτερόλεπτα
Zusammenfassung Die Zahl der in deutschen Notaufnahmen behandelten Patienten ist in den letzten Jahren auf ca. 20 Mio. Patienten angestiegen. Diese Steigerung betrifft auch die dort behandelten neurologischen Symptome und Erkrankungen, die bei etwa 20 % der Notaufnahmepatienten vorliegen. Neben dringlich zu behandelnden Patienten mit Schlaganfällen oder entzündlichen oder degenerativen Erkrankungen des Zentralnervensystems und Erkrankungen des peripheren Nervensystems suchen auch zunehmend Patienten mit unspezifischen Beschwerden und Symptomen oder elektiv zu behandelnden Erkranku...περισσότερα »
Nichtinvasive Stimulationsverfahren in der Neurologie
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 23 δευτερόλεπτα
Zusammenfassung Transkranielle Gleichstromstimulation (tDCS) ist mittlerweile ein gängiges Verfahren in den Neurowissenschaften, mit dem sich kognitive Funktionen modulieren lassen. Aktuelle Studien legen nahe, dass über die Modulation neuronaler Aktivität und Konnektivität eine Verbesserung der behavioralen Leistung erzielt werden kann. Demnach stellt die tDCS auch im klinischen Kontext ein vielversprechendes Verfahren zur Restitution beeinträchtigter Funktionen des Gedächtnisses infolge der Alzheimer-Krankheit oder der Aphasie nach einem Schlaganfall dar. Jedoch gibt es bisher nu... περισσότερα »
The Parkinson Disease Mitochondrial Hypothesis: Where Are We at?
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 23 δευτερόλεπτα
Parkinson's disease is a common, adult-onset neurodegenerative disorder whose pathogenesis is still under intense investigation. Substantial evidence from postmortem human brain tissue, genetic- and toxin-induced animal and cellular models indicates that mitochondrial dysfunction plays a central role in the pathophysiology of the disease. This review discusses our current understanding of Parkinson's disease–related mitochondrial dysfunction, including bioenergetic defects, mitochondrial DNA alterations, altered mitochondrial dynamics, activation of mitochondrial-dependent program... περισσότερα »
From Molecular Circuit Dysfunction to Disease: Case Studies in Epilepsy, Traumatic Brain Injury, and Alzheimers Disease
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 23 δευτερόλεπτα
Complex circuitry with feed-forward and feed-back systems regulate neuronal activity throughout the brain. Cell biological, electrical, and neurotransmitter systems enable neural networks to process and drive the entire spectrum of cognitive, behavioral, and motor functions. Simultaneous orchestration of distinct cells and interconnected neural circuits relies on hundreds, if not thousands, of unique molecular interactions. Even single molecule dysfunctions can be disrupting to neural circuit activity, leading to neurological pathology. Here, we sample our current understanding of...περισσότερα »
A simple care bundle for use in acute kidney injury: A propensity score matched cohort study
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Nephrology Dialysis Transplantation from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1T5AzGp
Potential barriers for achieving exercise maintenance among trauma exposed female veterans with Fibromyalgia
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
The Journal of Pain from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Wop7vh
Sulphonylurea compared to DPP-4 inhibitors in combination with metformin carries increased risk of severe hypoglycemia, cardiovascular events, and all-cause mortality
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Diabetes Research and Clinical Practice from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1T5AzGk
Higher mortality rates amongst emergency patients admitted to hospital at weekends reflect a lower probability of admission
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Journal of Health Services Research & Policy from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Wop7v6
Association between pain and itch symptom severity after major thermal burn injury increases over time
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
The Journal of Pain from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1T5AzpS
Trauma exposure and pain severity among people with chronic lower back pain: moderated mediation by thought suppression and social constraints
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
The Journal of Pain from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Wop7ev
Does childhood trauma influence offspring’s birth characteristics?
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
International Journal of Epidemiology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1T5Axyf
Associations between post-traumatic stress disorder symptoms and mental health in fibromyalgia
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
The Journal of Pain from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1T4pdFO
Decontamination of the pediatric patient
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Current Opinion in Pediatrics from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1ZEvw3w
Pigtail catheters vs traditional chest tubes and the risk of post pull pneumothorax in trauma patients
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
The Journal of Pain from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Wop6Hs
Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.
Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 30 δευτερόλεπτα
*Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.* Proc Natl Acad Sci U S A. 2016 May 9; Authors: Gross CC, Schulte-Mecklenbeck A, Rünzi A, Kuhlmann T, Posevitz-Fejfár A, Schwab N, Schneider-Hohendorf T, Herich S, Held K, Konjević M, Hartwig M, Dornmair K, Hohlfeld R, Ziemssen T, Klotz L, Meuth SG, Wiendl H Abstract Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system (CNS) resulting from a breakdown in peripheral immune tolerance. Although a beneficial role of natu... περισσότερα »
Maternal versus adolescent reports of suicidal behaviors: a nationwide survey in Israel.
Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 30 δευτερόλεπτα
*Maternal versus adolescent reports of suicidal behaviors: a nationwide survey in Israel.* Eur Child Adolesc Psychiatry. 2016 May 9; Authors: Zalsman G, Shoval G, Mansbach-Kleinfeld I, Farbstein I, Kanaaneh R, Lubin G, Apter A Abstract Community and nationwide surveys on adolescent suicidal behaviors using clinical interviews are not abundant. Rates of self-reported suicide attempts in community samples vary greatly between 1 and 20 %. In general, adolescent and parental agreement in child psychiatry practice is low, and their agreement with regard to suicidal behavior is unknown... περισσότερα »
Clinical Management of Head and Neck Cancer Cases: Role of Pharmacogenetics of CYP2 and GSTs.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 44 δευτερόλεπτα
*Clinical Management of Head and Neck Cancer Cases: Role of Pharmacogenetics of CYP2 and GSTs.* Oncol Res Treat. 2016;39(4):221-6 Authors: Ruwali M, Dhawan A, Pant MC, Rahman Q, Khurana SM, Parmar D Abstract Head and neck squamous cell carcinoma (HNSCC) describes a wide range of malignant tumors which originate in the upper aerodigestive tract and have a multifactorial origin involving both genetic and lifestyle risk factors. The clinical management of head and neck cancer involves surgery, radiotherapy, and chemotherapy. With the advances in treatment strategies for HNSCC, newer... περισσότερα »
Afatinib in Squamous Cell Carcinoma of the Head and Neck.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 44 δευτερόλεπτα
*Afatinib in Squamous Cell Carcinoma of the Head and Neck.* Expert Opin Pharmacother. 2016 May 10; Authors: Specenier P, Vermorken J Abstract Introduction Recently new data on the efficacy of afatinib in head and neck squamous cell carcinoma (HNSCC) have been published. Areas covered We searched the literature for published and ongoing studies with afatinib in HNSCC. Phase I data and results of phase II and III studies of afatinib in HNSCC are discussed. The maximum tolerated dose (MTD) of afatinib monotherapy with continuous administration was determined at 40 or 50 mg/day, rash... περισσότερα »
Anti EGFR therapy in the treatment of non-metastatic head and neck squamous cell carcinoma: The current evidence.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 44 δευτερόλεπτα
*Anti EGFR therapy in the treatment of non-metastatic head and neck squamous cell carcinoma: The current evidence.* J Egypt Natl Canc Inst. 2016 May 6; Authors: Benson R, Mallick S, Julka PK, Rath GK Abstract Head and neck squamous cell carcinoma (HNSCC) accounts for a large oncologic burden in the developing countries. In patients with locally advanced head and neck cancer multimodality treatment is warranted. Radiation therapy with concurrent chemotherapy has long been considered the standard for patients with disease involving the oropharynx, larynx and hypopharynx. However, a... περισσότερα »
Fluorometric Assay Platform for Caffeic Acid Detection Based on the G-quadruplex/hemin DNAzyme
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Analyst*, 2016, Accepted Manuscript *DOI*: 10.1039/C6AN00543H, Paper Nan Cai, Yan Li, shufan Chen, Xingguang Su In this paper, a fluorometric assay platform for fluorescent detection of caffeic acid was designed based on the peroxidase-mimicking activities of G-quadruplex/hemin DNAzyme. Under the catalysis of formed G-quadruplex/hemin complex,... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1TQmK0G via IFTTT
Use of fluorescence signals generated by elastic scattering under monochromatic incident light for determining the scattering efficiencies of various plasmonic nanoparticles
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Analyst*, 2016, Accepted Manuscript *DOI*: 10.1039/C6AN00399K, Paper JiEun Song, Ji Hoon Park, Ju A La, Seyeon Park, Min Kuk Jeong, Eun Chul Cho We present a route that estimates the scattering/absorption characteristics of plasmonic nanoparticles by using fluorescence and UV-visible spectroscopy. Because elastic scattering of nanoparticles caused by a monochromatic incident light are... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1TQmHSB via IFTTT
From Molecular Circuit Dysfunction to Disease: Case Studies in Epilepsy, Traumatic Brain Injury, and Alzheimers Disease
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Complex circuitry with feed-forward and feed-back systems regulate neuronal activity throughout the brain. Cell biological, electrical, and neurotransmitter systems enable neural networks to process and drive the entire spectrum of cognitive, behavioral, and motor functions. Simultaneous orchestration of distinct cells and interconnected neural circuits relies on hundreds, if not thousands, of unique molecular interactions. Even single molecule dysfunctions can be disrupting to neural circuit activity, leading to neurological pathology. Here, we sample our current understanding of...περισσότερα »
Perspectives on Neuroscience and Behavior
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
from Neurology via xlomafota13 on Inoreader http://ift.tt/1Wpr379 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TaHTmk via IFTTT
How Schwann Cells Sort Axons: New Concepts
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Peripheral nerves contain large myelinated and small unmyelinated (Remak) fibers that perform different functions. The choice to myelinate or not is dictated to Schwann cells by the axon itself, based on the amount of neuregulin I–type III exposed on its membrane. Peripheral axons are more important in determining the final myelination fate than central axons, and the implications for this difference in Schwann cells and oligodendrocytes are discussed. Interestingly, this choice is reversible during pathology, accounting for the remarkable plasticity of Schwann cells, and contribut... περισσότερα »
Integrating Levels of Analysis in Systems and Cognitive Neurosciences: Selective Attention as a Case Study
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Neuroscience is inherently interdisciplinary, rapidly expanding beyond its roots in biological sciences to many areas of the social and physical sciences. This expansion has led to more sophisticated ways of thinking about the links between brains and behavior and has inspired the development of increasingly advanced tools to characterize the activity of large populations of neurons. However, along with these advances comes a heightened risk of fostering confusion unless efforts are made to better integrate findings across different model systems and to develop a better understand... περισσότερα »
Hippocampal Wnt Signaling: Memory Regulation and Hormone Interactions
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Wnt signaling has emerged in recent years as a major player in both nervous system development and adult synaptic plasticity. Of particular relevance to researchers studying learning and memory, Wnt signaling is critical for normal functioning of the hippocampus, a brain region that is essential for many types of memory formation and whose dysfunction is implicated in numerous neurodegenerative and psychiatric conditions. Impaired hippocampal Wnt signaling is implicated in several of these conditions, however, little is known about how Wnt signaling mediates hippocampal memory form... περισσότερα »
Cholinergic Mechanisms in the Cerebral Cortex: Beyond Synaptic Transmission
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Functional overviews of cholinergic mechanisms in the cerebral cortex have traditionally focused on the release of acetylcholine with modulator and transmitter effects. Recently, however, data have emerged that extend the role of acetylcholine and cholinergic innervations to a range of housekeeping and metabolic functions. These include regulation of amyloid precursor protein (APP) processing with production of amyloid β (Aβ) and other APP fragments and control of the phosphorylation of microtubule-associated protein (MAP) tau. Evidence has been also presented for receptor-ligand ... περισσότερα »
Syntactic Awareness and Text Production in Brazilian Portuguese Students with Learning Disabilities
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
*Aims:* This study compared the syntactic awareness and textual production skills of school children and teenagers with and without learning disabilities (LD) and related their performances in both skills. *Methods:* The study group consisted of 15 children with an LD and 15 without language and learning alterations. To compare the performance of both groups, data were statistically analyzed using Fisher's exact test, and the association between the evidence in each group was demonstrated by Spearman's correlations, with a significance level of 5% (p *Results:* Most subjects with LD... περισσότερα »
Neuromuscular Electrical Stimulation for Treatment-Refractory Chronic Dysphagia in Tube-Fed Patients: A Prospective Case Series.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
*Neuromuscular Electrical Stimulation for Treatment-Refractory Chronic Dysphagia in Tube-Fed Patients: A Prospective Case Series.* Folia Phoniatr Logop. 2016 May 5;67(6):308-314 Authors: Scarponi L, Mozzanica F, De Cristofaro V, Ginocchio D, Pizzorni N, Bottero A, Schindler A Abstract OBJECTIVE: The aim of this study was to evaluate the role of neuromuscular electrical stimulation (NMES) in tube-fed patients with severe and chronic dysphagia refractory to traditional swallowing therapy (TT). PATIENTS AND METHODS: A total of 11 consecutive dysphagic patients with tube-dependent nut... περισσότερα »
Synthesis and Piezochromic Luminescence Study of a Coumarin Hydrozone Compound
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC02937J, Communication Haiyan Yu, Wang Ren, Hongguang Lu, Yanan Liang, Qiusheng Wang A novel coumarin hydrozone compound which exhibits piezochromic luminescence upon grinding was prepared. The piezofluorochromic properties were reversible upon fuming or heating. The intermolecular hydrogen bonds have been observed with... The content of this RSS Feed (c) The Royal Society of Chemistry [image: 21W6vTi] from BioChemistry via xlomafota13 on Inoreader http://ift.tt/27dkOGT via IFTTT from #Med Blogs by Al...περισσότερα »
Using topic coding to understand the nature of change language in a motivational intervention to reduce alcohol and sex risk behaviors in emergency department patients.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
*Using topic coding to understand the nature of change language in a motivational intervention to reduce alcohol and sex risk behaviors in emergency department patients.* Patient Educ Couns. 2016 May 2; Authors: Kahler CW, Caswell AJ, Laws MB, Walthers J, Magill M, Mastroleo NR, Howe CJ, Souza T, Wilson I, Bryant K, Monti PM Abstract OBJECTIVE: To elucidate patient language that supports changing a health behavior (change talk) or sustaining the behavior (sustain talk). METHODS: We developed a novel coding system to characterize topics of patient speech in a motivational intervent... περισσότερα »
Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
*Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.* Int J Audiol. 2016 May 10;:1-7 Authors: Rousset A, Dowell R, Leigh J Abstract OBJECTIVE: This study investigated outcomes and predictive factors, specifically language skills, for a group of prelingually hearing-impaired adults who received a cochlear implant. DESIGN: Speech perception data, demographic information, and other related variables such as communication mode, residual hearing, and receptive language abilities were explored. Pre- and post-implant speech perception scores were ... περισσότερα »
Aging Effect on Korean Female Voice: Acoustic and Perceptual Examinations of Breathiness.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
*Aging Effect on Korean Female Voice: Acoustic and Perceptual Examinations of Breathiness.* Folia Phoniatr Logop. 2016 May 5;67(6):300-307 Authors: Lee SJ, Cho Y, Song JY, Lee D, Kim Y, Kim H Abstract OBJECTIVE: This paper sought to examine perceptual and acoustic characteristics in Korean female voices, focusing on the 'breathy' quality as a function of aging. In addition, we aimed to investigate if the three selected measures, H1-H2, H1-A1, and H1-A3, demonstrated any changes along a sustained vowel production. PARTICIPANTS AND METHODS: A total of 42 participants were assigned t... περισσότερα »
Experience-dependent enhancement of pitch-specific responses in the auditory cortex is limited to acceleration rates in normal voice range.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Experience-dependent enhancement of pitch-specific responses in the auditory cortex is limited to acceleration rates in normal voice range.* Neuroscience. 2015 Sep 10;303:433-45 Authors: Krishnan A, Gandour JT, Suresh CH Abstract The aim of this study is to determine how pitch acceleration rates within and outside the normal pitch range may influence latency and amplitude of cortical pitch-specific responses (CPR) as a function of language experience (Chinese, English). Responses were elicited from a set of four ... περισσότερα »
Differences in Velopharyngeal Structure during Speech among Asians Revealed by 3-Tesla Magnetic Resonance Imaging Movie Mode.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--images.hindawi.com-linkout-hindaw] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Differences in Velopharyngeal Structure during Speech among Asians Revealed by 3-Tesla Magnetic Resonance Imaging Movie Mode.* Biomed Res Int. 2015;2015:126264 Authors: Nunthayanon K, Honda E, Shimazaki K, Ohmori H, Inoue-Arai MS, Kurabayashi T, Ono T Abstract OBJECTIVE: Different bony structures can affect the function of the velopharyngeal muscles. Asian populations differ morphologically, including the morphologies of their bony structures. The purpose of this study was to...περισσότερα »
Using topic coding to understand the nature of change language in a motivational intervention to reduce alcohol and sex risk behaviors in emergency department patients.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
*Using topic coding to understand the nature of change language in a motivational intervention to reduce alcohol and sex risk behaviors in emergency department patients.* Patient Educ Couns. 2016 May 2; Authors: Kahler CW, Caswell AJ, Laws MB, Walthers J, Magill M, Mastroleo NR, Howe CJ, Souza T, Wilson I, Bryant K, Monti PM Abstract OBJECTIVE: To elucidate patient language that supports changing a health behavior (change talk) or sustaining the behavior (sustain talk). METHODS: We developed a novel coding system to characterize topics of patient speech in a motivational intervent... περισσότερα »
Declines in stillbirth and neonatal mortality rates in Europe between 2004 and 2010: results from the Euro-Peristat project
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background Stillbirth and neonatal mortality rates declined in Europe between 2004 and 2010. We hypothesised that declines might be greater for countries with higher mortality in 2004 and disproportionally affect very preterm infants at highest risk. Methods Data about live births, stillbirths and neonatal deaths by gestational age (GA) were collected using a common protocol […]
CD4 count at antiretroviral therapy initiation and the risk of loss to follow-up: results from a multicentre cohort study
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background Antiretroviral therapy (ART) initiation is now recommended irrespective of CD4 count. However data on the relationship between CD4 count at ART initiation and loss to follow-up (LTFU) are limited and conflicting. Methods We conducted a cohort analysis including all adults initiating ART (2008–2012) at three public sector sites in South Africa. LTFU was defined […]
Tobacco and epidemiology in Korea: old tricks, new answers?
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
The National Health Insurance Service (NHIS) of Korea provides health insurance for over 90% of the population. The prevalence of smoking among Korean men is one of the highest in developed countries, and cancer incidence and mortality rates are the highest among all Asian countries.1 The NHIS has taken legal action against Korean and international […]
TB-HIV co-infection in the Netherlands: estimating prevalence and under-reporting in national registration databases using a capture-recapture analysis
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background Knowledge of the HIV status in patients with tuberculosis (TB) and vice versa is crucial for proper individual patient management, while knowledge of the prevalence of co-infection guides preventive and therapeutic strategies. The aim of the study was to assess if national disease databases on TB and HIV are adequate sources to provide this […]
An observational study of type, timing, and severity of childhood maltreatment and preterm birth
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background Childhood maltreatment has been linked to preterm birth (<37 weeks gestation) in some studies, but these findings have been inconsistent, and it remains unclear whether type, timing or severity of maltreatment are associated with risk of preterm birth. The aim of this observational study was to explore type of maltreatment (child and adolescent physical […]
Where do people live longer and shorter lives? An ecological study of old-age survival across 4404 small areas from 18 European countries
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background Further increases in life expectancy in high-income countries depend to a large extent on advances in old-age survival. We aimed to characterise the spatial distribution of old-age survival across small areas of Europe, and to identify areas with significantly high or low survivorship. Methods This study incorporated 4404 small areas from 18 European countries. […]
The physical activity profiles of South Asian ethnic groups in England
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background To identify what types of activity contribute to overall physical activity in South Asian ethnic groups and how these vary according to sex and age. We used the White British ethnic group as a comparison. Methods Self-reported physical activity was measured in the Health Survey for England 1999 and 2004, a nationally representative, cross-sectional […]
Dual blockade of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (FGF-2) exhibits potent anti-angiogenic effects
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: 28 July 2016 Source:Cancer Letters, Volume 377, Issue 2 Author(s): Dong Li, Kun Xie, Longzhen Zhang, Xuejing Yao, Hongwen Li, Qiaoyu Xu, Xin Wang, Jing Jiang, Jianmin Fang Both vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF or FGF-2) are potent pro-angiogenic factors and play a critical role in cancer […]
Alpha-synuclein and familial variants affect the chain order and the thermotropic phase behavior of anionic lipid vesicles
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 10 May 2016 Source:Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics Author(s): Manuela Pantusa, Brian Vad, Ove Lillelund, Lars Kjær, Daniel Otzen, Rosa Bartucci alpha-synuclein (aSN) is a presynaptic protein with a pathological role in Parkinson’s disease (PD). The mutants A30P, E46K and A53T are involved in PD early-onset forms. […]
The prognostic significance and impact of the CXCR4/CXCR7/CXCL12 axis in primary cutaneous melanoma
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Background Expression of the chemokine receptor CXCR4 is known to regulate melanoma metastasis to distant sites with high expression of CXCL12 ligand, but the prognostic impact of CXCR4 expression and potential for autocrine mediated activation of pro-survival mitogen-activated-protein-kinase signalling remains enigmatic. Furthermore expression of the decoy receptor CXCR7, within the local cutaneous melanoma microenvironment […]
Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
*Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.* Proc Natl Acad Sci U S A. 2016 May 9; Authors: Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF Abstract The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+T1R3, encoded by Tas1r2 and Tas1r3 genes). However, in the absence of T1R2+T1R3 (e.g., in Tas1r3 KO mice), animals still respond to sugars, argui... περισσότερα »
Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.* Chem Senses. 2015 Nov;40(9):605-8 Authors: Brion M, de Timary P, Vander Stappen C, Guettat L, Lecomte B, Rombaux P, Maurage P Abstract Chemosensory (olfaction-taste) dysfunctions are considered as reliable biomarkers in many neurological and psychiatric states. However, experimental measures of chemosensory abilities are lacking in alcohol-dependence (AD) and Korsakoff Syndrome (KS, a neurological complication of ... περισσότερα »
Where do people live longer and shorter lives? An ecological study of old-age survival across 4404 small areas from 18 European countries
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Background Further increases in life expectancy in high-income countries depend to a large extent on advances in old-age survival. We aimed to characterise the spatial distribution of old-age survival across small areas of Europe, and to identify areas with significantly high or low survivorship. Methods This study incorporated 4404 small areas from 18 European countries.… Continue reading Where do people live longer and shorter lives? An ecological study of old-age survival across 4404 small areas from 18 European countries
The influence of refugee status and secondary migration on preterm birth
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Background It is unknown whether the risk of preterm birth (PTB) is elevated for forced (refugee) international migrants and whether prolonged displacement amplifies risk. While voluntary migrants who arrive from a country other than their country of birth (ie, secondary migrants) have favourable birth outcomes compared with those who migrated directly from their country of… Continue reading The influence of refugee status and secondary migration on preterm birth
Syntactic Awareness and Text Production in Brazilian Portuguese Students with Learning Disabilities
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Aims: This study compared the syntactic awareness and textual production skills of school children and teenagers with and without learning disabilities (LD) and related their performances in both skills. Methods: The study group consisted of 15 children with an LD and 15 without language and learning alterations. To compare the performance of both groups, data… Continue reading Syntactic Awareness and Text Production in Brazilian Portuguese Students with Learning Disabilities
The physical activity profiles of South Asian ethnic groups in England
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Background To identify what types of activity contribute to overall physical activity in South Asian ethnic groups and how these vary according to sex and age. We used the White British ethnic group as a comparison. Methods Self-reported physical activity was measured in the Health Survey for England 1999 and 2004, a nationally representative, cross-sectional… Continue reading The physical activity profiles of South Asian ethnic groups in England
Neuromuscular Electrical Stimulation for Treatment-Refractory Chronic Dysphagia in Tube-Fed Patients: A Prospective Case Series.
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Neuromuscular Electrical Stimulation for Treatment-Refractory Chronic Dysphagia in Tube-Fed Patients: A Prospective Case Series. Folia Phoniatr Logop. 2016 May 5;67(6):308-314 Authors: Scarponi L, Mozzanica F, De Cristofaro V, Ginocchio D, Pizzorni N, Bottero A, Schindler A Abstract OBJECTIVE: The aim of this study was to evaluate the role of neuromuscular electrical stimulation (NMES) in tube-fed… Continue reading Neuromuscular Electrical Stimulation for Treatment-Refractory Chronic Dysphagia in Tube-Fed Patients: A Prospective Case Series.
Birth control policies in Iran: a public health and ethics perspective
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
In less than one generation, a unique demographic transition has taken place in Iran. A population growth rate of 4.06% in 1984 fell to 1.15% in 1993 and a total fertility rate of 6.4 births per woman in 1984 declined to 1.9 in 2010. In 2012, Iranian policymakers shifted away from a birth control policy… Continue reading Birth control policies in Iran: a public health and ethics perspective
Synthesis and Piezochromic Luminescence Study of a Coumarin Hydrozone Compound
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Chem. Commun., 2016, Accepted Manuscript DOI: 10.1039/C6CC02937J, Communication Haiyan Yu, Wang Ren, Hongguang Lu, Yanan Liang, Qiusheng Wang A novel coumarin hydrozone compound which exhibits piezochromic luminescence upon grinding was prepared. The piezofluorochromic properties were reversible upon fuming or heating. The intermolecular hydrogen bonds have been observed with… The content of this RSS Feed (c)… Continue reading Synthesis and Piezochromic Luminescence Study of a Coumarin Hydrozone Compound
Socioeconomic status, comorbidity and mortality in patients with type 2 diabetes mellitus in Scotland 2004-2011: a cohort study
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Background Mortality in people with and without diabetes often exhibits marked social patterning, risk of death being greater in deprived groups. This may reflect deprivation-related differences in comorbid disease (conditions additional to diabetes itself). This study sought to determine whether the social patterning of mortality in a population with type 2 diabetes mellitus (T2DM) is… Continue reading Socioeconomic status, comorbidity and mortality in patients with type 2 diabetes mellitus in Scotland 2004-2011: a cohort study
Tracking socioeconomic inequalities in mortality in a cohort of 11 868 men and women born in Uppsala, Sweden, 1915-1929
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Background Ample evidence has shown that early-life social conditions are associated with mortality later in life. However, little attention has been given to the strength of these effects across specific age intervals from birth to old age. In this paper, we study the effect of the family’s socioeconomic position and mother’s marital status at birth… Continue reading From cradle to grave: tracking socioeconomic inequalities in mortality in a cohort of 11 868 men and women born in Uppsala, Sweden, 1915-1929
A FT-NIR spectroscopy methodology for estimating the firing distance based on the direct analysis of the bullet impact surface
orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Analyst, 2016, Accepted Manuscript DOI: 10.1039/C6AN00247A, Paper Jorge Sarraguca, Catarina Lima, Filipe Machado, Joao Lopes, Agostinho A Almeida, Luis Fernandes, Teresa Magalhaes, Agostinho Santos A new methodology to estimate the firing distance based on the direct analysis of organic components of gunshot residues (GSR) on the bullet impact surface using Fourier transform near-infrared (FT-NIR)… The… Continue reading A FT-NIR spectroscopy methodology for estimating the firing distance based on the direct analysis of the bullet impact surface
First presentation of Addison’s disease as hyperkalaemia in acute kidney injury
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Addison’s disease is a rare endocrine disorder that frequently presents with non-specific symptoms, but may deteriorate rapidly into life-threatening Addisonian crisis if left untreated. Diagnosis can be difficult in patients without a suggestive medical history. We describe a case of a 37-year-old man who was admitted with acute kidney injury and hyperkalaemia, resistant to treatment […]
Reconstruction of a complicated adjacent non-union of the radius and ulna using a free vascularised double-barrel fibula graft
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
While the free vascularised double-barrel fibula flap has been traditionally used in the reconstruction of defects in the long bones of the lower extremities, the advantages of this type of graft can also be seen in the treatment of adjacent radial and ulnar non-unions of the forearm. The main advantage of the double-barrel fibula flap […]
Bilateral dacryoadenitis as initial presentation of a locally aggressive and unresponsive limited form of orbital granulomatosis with polyangiitis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Limited orbital granulomatosis with polyangiitis (GPA) is uncommon and its diagnosis may be delayed, especially when isolated lacrimal involvement is the initial presentation, because clinical manifestations are non-specific and systemic diagnostic criteria are not applicable. Making an early diagnosis despite the absence of systemic progression is extremely important because in some cases the disease is […]
MRI and CBCT image registration of temporomandibular joint: a systematic review
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Purpose The purpose of the present review is to systematically and critically analyze the available literature regarding the importance, applicability, and practicality of (MRI), computerized tomography (CT) or cone-beam CT (CBCT) image registration for TMJ anatomy and assessment. Data sources A systematic search of 4 databases; MEDLINE, EMBASE, EBM reviews and Scopus, was conducted […]
Integrating Levels of Analysis in Systems and Cognitive Neurosciences: Selective Attention as a Case Study
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
Neuroscience is inherently interdisciplinary, rapidly expanding beyond its roots in biological sciences to many areas of the social and physical sciences. This expansion has led to more sophisticated ways of thinking about the links between brains and behavior and has inspired the development of increasingly advanced tools to characterize the activity of large populations of neurons. However, along with these advances comes a heightened risk of fostering confusion unless efforts are made to better integrate findings across different model systems and to develop a better understand... περισσότερα »
Hippocampal Wnt Signaling: Memory Regulation and Hormone Interactions
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
Wnt signaling has emerged in recent years as a major player in both nervous system development and adult synaptic plasticity. Of particular relevance to researchers studying learning and memory, Wnt signaling is critical for normal functioning of the hippocampus, a brain region that is essential for many types of memory formation and whose dysfunction is implicated in numerous neurodegenerative and psychiatric conditions. Impaired hippocampal Wnt signaling is implicated in several of these conditions, however, little is known about how Wnt signaling mediates hippocampal memory form... περισσότερα »
Cholinergic Mechanisms in the Cerebral Cortex: Beyond Synaptic Transmission
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
Functional overviews of cholinergic mechanisms in the cerebral cortex have traditionally focused on the release of acetylcholine with modulator and transmitter effects. Recently, however, data have emerged that extend the role of acetylcholine and cholinergic innervations to a range of housekeeping and metabolic functions. These include regulation of amyloid precursor protein (APP) processing with production of amyloid β (Aβ) and other APP fragments and control of the phosphorylation of microtubule-associated protein (MAP) tau. Evidence has been also presented for receptor-ligand ... περισσότερα »
Neuromuscular Electrical Stimulation for Treatment-Refractory Chronic Dysphagia in Tube-Fed Patients: A Prospective Case Series.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
*Neuromuscular Electrical Stimulation for Treatment-Refractory Chronic Dysphagia in Tube-Fed Patients: A Prospective Case Series.* Folia Phoniatr Logop. 2016 May 5;67(6):308-314 Authors: Scarponi L, Mozzanica F, De Cristofaro V, Ginocchio D, Pizzorni N, Bottero A, Schindler A Abstract OBJECTIVE: The aim of this study was to evaluate the role of neuromuscular electrical stimulation (NMES) in tube-fed patients with severe and chronic dysphagia refractory to traditional swallowing therapy (TT). PATIENTS AND METHODS: A total of 11 consecutive dysphagic patients with tube-dependent nut... περισσότερα »
Design, development and validation of a new laryngo-pharyngeal endoscopic esthesiometer and range-finder based on the assessment of air-pulse variability determinants.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
*Design, development and validation of a new laryngo-pharyngeal endoscopic esthesiometer and range-finder based on the assessment of air-pulse variability determinants.* Biomed Eng Online. 2016;15(1):52 Authors: Giraldo-Cadavid LF, Agudelo-Otalora LM, Burguete J, Arbulu M, Moscoso WD, Martínez F, Ortiz AF, Diaz J, Pantoja JA, Rueda-Arango AF, Fernández S Abstract BACKGROUND: Laryngo-pharyngeal mechano-sensitivity (LPMS) is involved in dysphagia, sleep apnea, stroke, irritable larynx syndrome and cough hypersensitivity syndrome among other disorders. These conditions are associat... περισσότερα »
Expanding Instrumental Options for Dysphagia Diagnosis and Research: Ultrasound and Manometry.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
*Expanding Instrumental Options for Dysphagia Diagnosis and Research: Ultrasound and Manometry.* Folia Phoniatr Logop. 2016 May 3;67(6):269-284 Authors: Huckabee ML, Macrae P, Lamvik K Abstract Diagnostic assessment of swallowing in routine clinical practice relies heavily on the long-standing techniques of videofluoroscopic swallowing study (VFSS) and videoendoscopic evaluation of swallowing (VEES). These complementary and sophisticated techniques provide a real-time visualization of biomechanical movements of the structures involved in swallowing and consequent effects on bolus... περισσότερα »
Swallowing outcomes following primary surgical resection and primary free flap reconstruction for oral and oropharyngeal squamous cell carcinomas: a systematic review protocol.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
Related Articles *Swallowing outcomes following primary surgical resection and primary free flap reconstruction for oral and oropharyngeal squamous cell carcinomas: a systematic review protocol.* JBI Database System Rev Implement Rep. 2015;13(8):120-34 Authors: Kao SS, Ooi EH, Peters MD PMID: 26455941 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1X0r6F3
Ghrelin and Leptin Have a Complex Relationship with Risk of Barrett's Esophagus.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *Ghrelin and Leptin Have a Complex Relationship with Risk of Barrett's Esophagus.* Dig Dis Sci. 2016 Jan;61(1):70-9 Authors: Thomas SJ, Almers L, Schneider J, Graham JE, Havel PJ, Corley DA Abstract BACKGROUND: Abdominal obesity is a risk factor for Barrett's esophagus independent of GERD symptoms, but little is understood about the biological mechanisms between obesity and the carcinogenic pathway of esophageal adenocarcinoma. AIMS: To evaluate whether ghrelin and leptin may partially explain the association betwe... περισσότερα »
Design, development and validation of a new laryngo-pharyngeal endoscopic esthesiometer and range-finder based on the assessment of air-pulse variability determinants.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
*Design, development and validation of a new laryngo-pharyngeal endoscopic esthesiometer and range-finder based on the assessment of air-pulse variability determinants.* Biomed Eng Online. 2016;15(1):52 Authors: Giraldo-Cadavid LF, Agudelo-Otalora LM, Burguete J, Arbulu M, Moscoso WD, Martínez F, Ortiz AF, Diaz J, Pantoja JA, Rueda-Arango AF, Fernández S Abstract BACKGROUND: Laryngo-pharyngeal mechano-sensitivity (LPMS) is involved in dysphagia, sleep apnea, stroke, irritable larynx syndrome and cough hypersensitivity syndrome among other disorders. These conditions are associat... περισσότερα »
Expanding Instrumental Options for Dysphagia Diagnosis and Research: Ultrasound and Manometry.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
*Expanding Instrumental Options for Dysphagia Diagnosis and Research: Ultrasound and Manometry.* Folia Phoniatr Logop. 2016 May 3;67(6):269-284 Authors: Huckabee ML, Macrae P, Lamvik K Abstract Diagnostic assessment of swallowing in routine clinical practice relies heavily on the long-standing techniques of videofluoroscopic swallowing study (VFSS) and videoendoscopic evaluation of swallowing (VEES). These complementary and sophisticated techniques provide a real-time visualization of biomechanical movements of the structures involved in swallowing and consequent effects on bolus... περισσότερα »
Swallowing outcomes following primary surgical resection and primary free flap reconstruction for oral and oropharyngeal squamous cell carcinomas: a systematic review protocol.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
Related Articles *Swallowing outcomes following primary surgical resection and primary free flap reconstruction for oral and oropharyngeal squamous cell carcinomas: a systematic review protocol.* JBI Database System Rev Implement Rep. 2015;13(8):120-34 Authors: Kao SS, Ooi EH, Peters MD PMID: 26455941 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1X0r6F3 via IFTTT
Ghrelin and Leptin Have a Complex Relationship with Risk of Barrett's Esophagus.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *Ghrelin and Leptin Have a Complex Relationship with Risk of Barrett's Esophagus.* Dig Dis Sci. 2016 Jan;61(1):70-9 Authors: Thomas SJ, Almers L, Schneider J, Graham JE, Havel PJ, Corley DA Abstract BACKGROUND: Abdominal obesity is a risk factor for Barrett's esophagus independent of GERD symptoms, but little is understood about the biological mechanisms between obesity and the carcinogenic pathway of esophageal adenocarcinoma. AIMS: To evaluate whether ghrelin and leptin may partially explain the association betw... περισσότερα »
Design, development and validation of a new laryngo-pharyngeal endoscopic esthesiometer and range-finder based on the assessment of air-pulse variability determinants.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
*Design, development and validation of a new laryngo-pharyngeal endoscopic esthesiometer and range-finder based on the assessment of air-pulse variability determinants.* Biomed Eng Online. 2016;15(1):52 Authors: Giraldo-Cadavid LF, Agudelo-Otalora LM, Burguete J, Arbulu M, Moscoso WD, Martínez F, Ortiz AF, Diaz J, Pantoja JA, Rueda-Arango AF, Fernández S Abstract BACKGROUND: Laryngo-pharyngeal mechano-sensitivity (LPMS) is involved in dysphagia, sleep apnea, stroke, irritable larynx syndrome and cough hypersensitivity syndrome among other disorders. These conditions are associat... περισσότερα »
Expanding Instrumental Options for Dysphagia Diagnosis and Research: Ultrasound and Manometry.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
*Expanding Instrumental Options for Dysphagia Diagnosis and Research: Ultrasound and Manometry.* Folia Phoniatr Logop. 2016 May 3;67(6):269-284 Authors: Huckabee ML, Macrae P, Lamvik K Abstract Diagnostic assessment of swallowing in routine clinical practice relies heavily on the long-standing techniques of videofluoroscopic swallowing study (VFSS) and videoendoscopic evaluation of swallowing (VEES). These complementary and sophisticated techniques provide a real-time visualization of biomechanical movements of the structures involved in swallowing and consequent effects on bolus... περισσότερα »
Swallowing outcomes following primary surgical resection and primary free flap reconstruction for oral and oropharyngeal squamous cell carcinomas: a systematic review protocol.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
Related Articles *Swallowing outcomes following primary surgical resection and primary free flap reconstruction for oral and oropharyngeal squamous cell carcinomas: a systematic review protocol.* JBI Database System Rev Implement Rep. 2015;13(8):120-34 Authors: Kao SS, Ooi EH, Peters MD PMID: 26455941 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1X0r6F3 via IFTTT
Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
*Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.* Proc Natl Acad Sci U S A. 2016 May 9; Authors: Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF Abstract The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+T1R3, encoded by Tas1r2 and Tas1r3 genes). However, in the absence of T1R2+T1R3 (e.g., in Tas1r3 KO mice), animals still respond to sugars, argui... περισσότερα »
Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.* Chem Senses. 2015 Nov;40(9):605-8 Authors: Brion M, de Timary P, Vander Stappen C, Guettat L, Lecomte B, Rombaux P, Maurage P Abstract Chemosensory (olfaction-taste) dysfunctions are considered as reliable biomarkers in many neurological and psychiatric states. However, experimental measures of chemosensory abilities are lacking in alcohol-dependence (AD) and Korsakoff Syndrome (KS, a neurological complication of A... περισσότερα »
The Insect Chemoreceptor Superfamily Is Ancient in Animals.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *The Insect Chemoreceptor Superfamily Is Ancient in Animals.* Chem Senses. 2015 Nov;40(9):609-14 Authors: Robertson HM Abstract The insect chemoreceptor superfamily consists of 2 gene families, the highly diverse gustatory receptors (GRs) found in all arthropods with sequenced genomes and the odorant receptors that evolved from a GR lineage and have been found only in insects to date. Here, I describe relatives of the insect chemoreceptor superfamily, specifically the basal GR family, in diverse other animals, show... περισσότερα »
Acoustic shadows help gleaning bats find prey, but may be defeated by prey acoustic camouflage on rough surfaces.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--cdn.elifesciences.org-images-elif] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Acoustic shadows help gleaning bats find prey, but may be defeated by prey acoustic camouflage on rough surfaces.* Elife. 2015;4 Authors: Clare EL, Holderied MW Abstract Perceptual abilities of animals, like echolocating bats, are difficult to study because they challenge our understanding of non-visual senses. We used novel acoustic tomography to convert echoes into visual representations and compare these cues to traditional echo measurements. We provide a new hypothesis fo...περισσότερα »
Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
*Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.* Proc Natl Acad Sci U S A. 2016 May 9; Authors: Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF Abstract The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+T1R3, encoded by Tas1r2 and Tas1r3 genes). However, in the absence of T1R2+T1R3 (e.g., in Tas1r3 KO mice), animals still respond to sugars, argui... περισσότερα »
Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.* Chem Senses. 2015 Nov;40(9):605-8 Authors: Brion M, de Timary P, Vander Stappen C, Guettat L, Lecomte B, Rombaux P, Maurage P Abstract Chemosensory (olfaction-taste) dysfunctions are considered as reliable biomarkers in many neurological and psychiatric states. However, experimental measures of chemosensory abilities are lacking in alcohol-dependence (AD) and Korsakoff Syndrome (KS, a neurological complication of ... περισσότερα »
The Insect Chemoreceptor Superfamily Is Ancient in Animals.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *The Insect Chemoreceptor Superfamily Is Ancient in Animals.* Chem Senses. 2015 Nov;40(9):609-14 Authors: Robertson HM Abstract The insect chemoreceptor superfamily consists of 2 gene families, the highly diverse gustatory receptors (GRs) found in all arthropods with sequenced genomes and the odorant receptors that evolved from a GR lineage and have been found only in insects to date. Here, I describe relatives of the insect chemoreceptor superfamily, specifically the basal GR family, in diverse other animals, sho... περισσότερα »
Acoustic shadows help gleaning bats find prey, but may be defeated by prey acoustic camouflage on rough surfaces.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--cdn.elifesciences.org-images-elif] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Acoustic shadows help gleaning bats find prey, but may be defeated by prey acoustic camouflage on rough surfaces.* Elife. 2015;4 Authors: Clare EL, Holderied MW Abstract Perceptual abilities of animals, like echolocating bats, are difficult to study because they challenge our understanding of non-visual senses. We used novel acoustic tomography to convert echoes into visual representations and compare these cues to traditional echo measurements. We provide a new hypothesis f...περισσότερα »
Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
*Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.* Proc Natl Acad Sci U S A. 2016 May 9; Authors: Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF Abstract The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+T1R3, encoded by Tas1r2 and Tas1r3 genes). However, in the absence of T1R2+T1R3 (e.g., in Tas1r3 KO mice), animals still respond to sugars, argui... περισσότερα »
Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
*Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.* Proc Natl Acad Sci U S A. 2016 May 9; Authors: Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF Abstract The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+T1R3, encoded by Tas1r2 and Tas1r3 genes). However, in the absence of T1R2+T1R3 (e.g., in Tas1r3 KO mice), animals still respond to sugars, argui... περισσότερα »
Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.* Chem Senses. 2015 Nov;40(9):605-8 Authors: Brion M, de Timary P, Vander Stappen C, Guettat L, Lecomte B, Rombaux P, Maurage P Abstract Chemosensory (olfaction-taste) dysfunctions are considered as reliable biomarkers in many neurological and psychiatric states. However, experimental measures of chemosensory abilities are lacking in alcohol-dependence (AD) and Korsakoff Syndrome (KS, a neurological complication of ... περισσότερα »
The Insect Chemoreceptor Superfamily Is Ancient in Animals.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *The Insect Chemoreceptor Superfamily Is Ancient in Animals.* Chem Senses. 2015 Nov;40(9):609-14 Authors: Robertson HM Abstract The insect chemoreceptor superfamily consists of 2 gene families, the highly diverse gustatory receptors (GRs) found in all arthropods with sequenced genomes and the odorant receptors that evolved from a GR lineage and have been found only in insects to date. Here, I describe relatives of the insect chemoreceptor superfamily, specifically the basal GR family, in diverse other animals, sho... περισσότερα »
Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
*Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.* Proc Natl Acad Sci U S A. 2016 May 9; Authors: Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF Abstract The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+T1R3, encoded by Tas1r2 and Tas1r3 genes). However, in the absence of T1R2+T1R3 (e.g., in Tas1r3 KO mice), animals still respond to sugars, argui... περισσότερα »
Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Chemosensory Dysfunction in Alcohol-Related Disorders: A Joint Exploration of Olfaction and Taste.* Chem Senses. 2015 Nov;40(9):605-8 Authors: Brion M, de Timary P, Vander Stappen C, Guettat L, Lecomte B, Rombaux P, Maurage P Abstract Chemosensory (olfaction-taste) dysfunctions are considered as reliable biomarkers in many neurological and psychiatric states. However, experimental measures of chemosensory abilities are lacking in alcohol-dependence (AD) and Korsakoff Syndrome (KS, a neurological complication of A... περισσότερα »
The Insect Chemoreceptor Superfamily Is Ancient in Animals.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *The Insect Chemoreceptor Superfamily Is Ancient in Animals.* Chem Senses. 2015 Nov;40(9):609-14 Authors: Robertson HM Abstract The insect chemoreceptor superfamily consists of 2 gene families, the highly diverse gustatory receptors (GRs) found in all arthropods with sequenced genomes and the odorant receptors that evolved from a GR lineage and have been found only in insects to date. Here, I describe relatives of the insect chemoreceptor superfamily, specifically the basal GR family, in diverse other animals, show... περισσότερα »
Acoustic shadows help gleaning bats find prey, but may be defeated by prey acoustic camouflage on rough surfaces.
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα
[image: http:--cdn.elifesciences.org-images-elif] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Acoustic shadows help gleaning bats find prey, but may be defeated by prey acoustic camouflage on rough surfaces.* Elife. 2015;4 Authors: Clare EL, Holderied MW Abstract Perceptual abilities of animals, like echolocating bats, are difficult to study because they challenge our understanding of non-visual senses. We used novel acoustic tomography to convert echoes into visual representations and compare these cues to traditional echo measurements. We provide a new hypothesis fo...περισσότερα »
Synthesis and Piezochromic Luminescence Study of a Coumarin Hydrozone Compound
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC02937J, Communication Haiyan Yu, Wang Ren, Hongguang Lu, Yanan Liang, Qiusheng Wang A novel coumarin hydrozone compound which exhibits piezochromic luminescence upon grinding was prepared. The piezofluorochromic properties were reversible upon fuming or heating. The intermolecular hydrogen bonds have been observed with... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/27dkOGT via IFTTT
A FT-NIR spectroscopy methodology for estimating the firing distance based on the direct analysis of the bullet impact surface
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Analyst*, 2016, Accepted Manuscript *DOI*: 10.1039/C6AN00247A, Paper Jorge Sarraguca, Catarina Lima, Filipe Machado, Joao Lopes, Agostinho A Almeida, Luis Fernandes, Teresa Magalhaes, Agostinho Santos A new methodology to estimate the firing distance based on the direct analysis of organic components of gunshot residues (GSR) on the bullet impact surface using Fourier transform near-infrared (FT-NIR)... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1ZEFwtr via IFTTT
Syntactic Awareness and Text Production in Brazilian Portuguese Students with Learning Disabilities
Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
*Aims:* This study compared the syntactic awareness and textual production skills of school children and teenagers with and without learning disabilities (LD) and related their performances in both skills. *Methods:* The study group consisted of 15 children with an LD and 15 without language and learning alterations. To compare the performance of both groups, data were statistically analyzed using Fisher's exact test, and the association between the evidence in each group was demonstrated by Spearman's correlations, with a significance level of 5% (p *Results:* Most subjects with LD... περισσότερα »
Syntactic Awareness and Text Production in Brazilian Portuguese Students with Learning Disabilities
Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
*Aims:* This study compared the syntactic awareness and textual production skills of school children and teenagers with and without learning disabilities (LD) and related their performances in both skills. *Methods:* The study group consisted of 15 children with an LD and 15 without language and learning alterations. To compare the performance of both groups, data were statistically analyzed using Fisher's exact test, and the association between the evidence in each group was demonstrated by Spearman's correlations, with a significance level of 5% (p *Results:* Most subjects with LD... περισσότερα »
Oxidative stress and the subcellular localization of the telomerase reverse transcriptase (TERT) in papillary thyroid cancer.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*Oxidative stress and the subcellular localization of the telomerase reverse transcriptase (TERT) in papillary thyroid cancer.* Mol Cell Endocrinol. 2016 May 6; Authors: Muzza M, Colombo C, Cirello V, Perrino M, Vicentini L, Fugazzola L Abstract During hormonogenesis, thyrocytes are physiologically exposed to high levels of oxidative stress (OS) which could either be involved in the pathogenesis of thyroid cancer or exert a cytotoxic effect. We analyzed the oxidative status of papillary thyroid cancer (PTC) both directly, by measuring H2O2 generation by NADPH oxidases (NOXs), and ... περισσότερα »
Thyroid Paraganglioma: Our Experience and Systematic Review of the Literature on a Rare Tumor.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*Thyroid Paraganglioma: Our Experience and Systematic Review of the Literature on a Rare Tumor.* Am J Clin Oncol. 2016 May 9; Authors: Pelizzo MR, Conti C, Pennelli G, Bellan E, Cook GJ, Wong KK, Colletti PM, Merante Boschin I, Rubello D Abstract INTRODUCTION: Primary paraganglioma (PG) of the thyroid gland is an extremely rare neuroendocrine tumor with potential for misdiagnosis. We describe 2 cases of thyroid PG, suggest a possible diagnostic and therapeutic management strategy, and present a systematic review of the literature. CASE REPORTS: Two 67-year-old women presented sim... περισσότερα »
MicroRNA Expression Profiles in Papillary Thyroid Carcinoma, Benign Thyroid Nodules and Healthy Controls.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*MicroRNA Expression Profiles in Papillary Thyroid Carcinoma, Benign Thyroid Nodules and Healthy Controls.* J Cancer. 2016;7(7):803-9 Authors: Yoruker EE, Terzioglu D, Teksoz S, Uslu FE, Gezer U, Dalay N Abstract MicroRNAs (miRNAs) represent a class of short endogenous non-coding RNAs that negatively regulate gene expression at the post-transcriptional level in many biological processes, including proliferation, differentiation, stress response and apoptosis. In this study we analyzed a set of seven miRNA molecules in sera of patients with papillary thyroid cancer, multinodular g... περισσότερα »
Prospective cohort study of febrile neutropenia in breast cancer patients with neoadjuvant and adjuvant chemotherapy: CSPOR-BC FN study.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*Prospective cohort study of febrile neutropenia in breast cancer patients with neoadjuvant and adjuvant chemotherapy: CSPOR-BC FN study.* Jpn J Clin Oncol. 2016 May 9; Authors: Ishikawa T, Sakamaki K, Narui K, Kaise H, Tsugawa K, Ichikawa Y, Mukai H, for Comprehensive Support Project for Oncological Research of Breast Cancer Abstract With the increasing use of adjuvant chemotherapy for treating early breast cancer, febrile neutropenia management has become crucial. Guidelines for febrile neutropenia management are mostly based on a Caucasian population survey although ethnic dif... περισσότερα »
Minimally invasive video-assisted lateral neck lymphadenectomy for the papillary thyroid carcinoma with cervical lymph nodes metastasis.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*Minimally invasive video-assisted lateral neck lymphadenectomy for the papillary thyroid carcinoma with cervical lymph nodes metastasis.* Jpn J Clin Oncol. 2016 May 9; Authors: Li B, Zhao W, Xu L, Sun J, Chen B, Yu G, Ye L, Gong M, Cong W, Qi Y PMID: 27162317 [PubMed - as supplied by publisher] from pubmed: thyroid cancer http://ift.tt/1rUwQnO via IFTTT
Management of the thyroid gland by salvage surgery for hypopharyngeal and cervical esophageal carcinoma after chemoradiotherapy.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*Management of the thyroid gland by salvage surgery for hypopharyngeal and cervical esophageal carcinoma after chemoradiotherapy.* Jpn J Clin Oncol. 2016 May 9; Authors: Okano W, Hayashi R, Omori K, Shinozaki T PMID: 27162316 [PubMed - as supplied by publisher] from pubmed: thyroid cancer http://ift.tt/1Oh9vai via IFTTT
Thyroid Paraganglioma Diagnosed by Fine-Needle Aspiration Biopsy, Correlated With Histopathological Findings: Report of a Case.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*Thyroid Paraganglioma Diagnosed by Fine-Needle Aspiration Biopsy, Correlated With Histopathological Findings: Report of a Case.* Diagn Cytopathol. 2016 May 10; Authors: Çetin Ş, Kir G, Yilmaz M Abstract Thyroid paragangliomas are rare neuroendocrine tumors. They are difficult to diagnosis by fine-needle aspiration biopsy (FNAB) and can be misdiagnosed as other types of thyroid disease. Here, we present an unusual case of primary thyroid paraganglioma diagnosed by FNAB. A 66-year-old woman presented with multinodular goiter. Ultrasound (US)-guided FNAB of the 3 cm nodule in the s... περισσότερα »
Cancer incidence among Parkinson's disease patients in a 10-yrs time-window around disease onset: A large-scale cohort study.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*Cancer incidence among Parkinson's disease patients in a 10-yrs time-window around disease onset: A large-scale cohort study.* Parkinsonism Relat Disord. 2016 Apr 30; Authors: Peretz C, Gurel R, Rozani V, Gurevich T, El-Ad B, Tsamir J, Giladi N Abstract OBJECTIVE: To compare the incidences of any cancer and specific types among patients with Parkinson's disease (PD) in a 10-yrs time window around diagnosis, to that of the general population. METHODS: We conducted a population-based, retrospective large-scale cohort study on 7125 newly diagnosed PD patients who had just initiated ... περισσότερα »
Thyroid Cancer Specific Quality of Life and Health Related Quality of Life in Young Adult Thyroid Cancer Survivors.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*Thyroid Cancer Specific Quality of Life and Health Related Quality of Life in Young Adult Thyroid Cancer Survivors.* Thyroid. 2016 May 9; Authors: Goldfarb M, Casillas J Abstract BACKGROUND: There is a lack of health related quality of life (HRQOL) research in thyroid cancer (TC) survivors, especially young adults (YAs). This study aims to assess the sociodemographic and clinical factors that most influence TC-specific QOL domains and estimate the impact of different health conditions on HRQOL in a large cohort. METHODS: TC-survivors ≥17 years of age were recruited through the th... περισσότερα »
A Clinicopathologic Series of 685 Thyroglossal Duct Remnant Cysts.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*A Clinicopathologic Series of 685 Thyroglossal Duct Remnant Cysts.* Head Neck Pathol. 2016 May 9; Authors: Thompson LD, Herrera HB, Lau SK Abstract The clinical features of thyroglossal duct remnant cysts (TGDC) have been well described, however the histopathologic aspects of these lesions have not been addressed in a detailed manner. In particular, there has been no large community practice based series evaluating TGDC histologically compared with management outcomes. A retrospective review of all TGDC diagnosed between 2005 and 2015 was performed. Six hundred eighty-five patie... περισσότερα »
Volcanic environments: "biomonitoring" their links to thyroid cancer.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
*Volcanic environments: "biomonitoring" their links to thyroid cancer.* Endocrine. 2016 May 9; Authors: Duntas LH PMID: 27160818 [PubMed - as supplied by publisher] from pubmed: thyroid cancer http://ift.tt/1rUwP3v via IFTTT
Recalcitrant Hypocalcemia after Thyroidectomy in Patients Post Sleeve Gastrectomy--Challenges in Management.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
Related Articles *Recalcitrant Hypocalcemia after Thyroidectomy in Patients Post Sleeve Gastrectomy--Challenges in Management.* Am Surg. 2015 Dec;81(12):E426-7 Authors: Vemuri SR, Koganti SB, Mukerji A, Razi S, Shah A, Gilchrist BF PMID: 26736152 [PubMed - indexed for MEDLINE] from pubmed: thyroid cancer http://ift.tt/1Oh9u6e via IFTTT
The storage period of the formalin-fixed paraffin-embedded tumor blocks does not influence the concentration and purity of the isolated DNA in a series of 83 renal and thyroid carcinomas.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
Related Articles *The storage period of the formalin-fixed paraffin-embedded tumor blocks does not influence the concentration and purity of the isolated DNA in a series of 83 renal and thyroid carcinomas.* Rom J Morphol Embryol. 2015;56(2 Suppl):759-63 Authors: Nechifor-Boilă AC, Loghin A, Vacariu V, Halaţiu VB, Borda A Abstract Optimal recovery of nucleic acids from formalin-fixed paraffin-embedded (FFPE) tissues is highly dependent on a series of pre-extraction steps, mainly related (but not limited) to fixation. The aim of our study was to investigate if the storage period of... περισσότερα »
Should the patients with thyroid nodule who had benign fine-needle aspiration biopsy findings and suspicious ultrasonographic and clinical findings undergo surgery?
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
Related Articles *Should the patients with thyroid nodule who had benign fine-needle aspiration biopsy findings and suspicious ultrasonographic and clinical findings undergo surgery?* Diagn Cytopathol. 2015 Dec;43(12):1037-8 Authors: Kuru B PMID: 26303154 [PubMed - indexed for MEDLINE] from pubmed: thyroid cancer http://ift.tt/1rUwOwc via IFTTT
Cranio Spinal Irradiation of Medulloblastoma Using High Precision Techniques - A Dosimetric Comparison.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
Related Articles *Cranio Spinal Irradiation of Medulloblastoma Using High Precision Techniques - A Dosimetric Comparison.* Technol Cancer Res Treat. 2015 Aug;14(4):491-6 Authors: Pichandi A, Ganesh KM, Jerrin A, Balaji K, Sridhar PS, Surega A Abstract Radiotherapy planning, delivery and junction dose verification remain exigent for Cranio Spinal Irradiation (CSI) in medulloblastoma patients. This study aims to evaluate high precision techniques such as Intensity Modulated Radiation Therapy (IMRT), Rapid Arc Therapy (RA) with and without flattening filter (FF) on the basis of dosi... περισσότερα »
Intra-thyroid thyroglossal duct cyst: a case report and review of literature.
Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα
Related Articles *Intra-thyroid thyroglossal duct cyst: a case report and review of literature.* Int J Clin Exp Pathol. 2015;8(6):7229-33 Authors: Huang LD, Gao SQ, Dai RJ, Chen DD, He B, Shi HQ, Yang K, Shan YF Abstract Thyroglossal duct cyst is the most common congenital cyst in the head and neck, which is defined usually occurring in children. However, intra-thyroid thyroglossal duct cyst in an adult is unusually found. Here we describe a case of a 45-year-old woman who was found neck mass along the midline for 5 years. During the surgery we found a separated nodule in the le... περισσότερα »
[Progress of bendamustine in the treatment of B cell non-Hodgkin lymphoma].
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--journal.yiigle.com-r-cms-jiansuo-] Related Articles *[Progress of bendamustine in the treatment of B cell non-Hodgkin lymphoma].* Zhonghua Xue Ye Xue Za Zhi. 2015 Nov;36(11):972-6 Authors: Zhu H, Xu W, Li J PMID: 26632476 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1NuvLLf via IFTTT
Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
*Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.* Int J Audiol. 2016 May 10;:1-7 Authors: Rousset A, Dowell R, Leigh J Abstract OBJECTIVE: This study investigated outcomes and predictive factors, specifically language skills, for a group of prelingually hearing-impaired adults who received a cochlear implant. DESIGN: Speech perception data, demographic information, and other related variables such as communication mode, residual hearing, and receptive language abilities were explored. Pre- and post-implant speech perception scores were ... περισσότερα »
Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
*Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.* Int J Audiol. 2016 May 10;:1-7 Authors: Rousset A, Dowell R, Leigh J Abstract OBJECTIVE: This study investigated outcomes and predictive factors, specifically language skills, for a group of prelingually hearing-impaired adults who received a cochlear implant. DESIGN: Speech perception data, demographic information, and other related variables such as communication mode, residual hearing, and receptive language abilities were explored. Pre- and post-implant speech perception scores were ... περισσότερα »
Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
*Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.* Int J Audiol. 2016 May 10;:1-7 Authors: Rousset A, Dowell R, Leigh J Abstract OBJECTIVE: This study investigated outcomes and predictive factors, specifically language skills, for a group of prelingually hearing-impaired adults who received a cochlear implant. DESIGN: Speech perception data, demographic information, and other related variables such as communication mode, residual hearing, and receptive language abilities were explored. Pre- and post-implant speech perception scores were ... περισσότερα »
Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
*Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.* Int J Audiol. 2016 May 10;:1-7 Authors: Rousset A, Dowell R, Leigh J Abstract OBJECTIVE: This study investigated outcomes and predictive factors, specifically language skills, for a group of prelingually hearing-impaired adults who received a cochlear implant. DESIGN: Speech perception data, demographic information, and other related variables such as communication mode, residual hearing, and receptive language abilities were explored. Pre- and post-implant speech perception scores were ... περισσότερα »
Partial to complete suppression of unilateral noise-induced tinnitus in rats after cyclobenzaprine treatment.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 2 ώρες
[image: http:--production.springer.de-OnlineReso] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Partial to complete suppression of unilateral noise-induced tinnitus in rats after cyclobenzaprine treatment.* J Assoc Res Otolaryngol. 2015 Apr;16(2):263-72 Authors: Lobarinas E, Blair C, Spankovich C, Le Prell C Abstract Some forms of tinnitus are believed to arise from abnormal central nervous system activity following a single or repeated noise exposure, for which there are no widely accepted pharmacological treatments. One central site that could be related to tinnitus a... περισσότερα »
Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.
Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 2 ώρες
*Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults.* Int J Audiol. 2016 May 10;:1-7 Authors: Rousset A, Dowell R, Leigh J Abstract OBJECTIVE: This study investigated outcomes and predictive factors, specifically language skills, for a group of prelingually hearing-impaired adults who received a cochlear implant. DESIGN: Speech perception data, demographic information, and other related variables such as communication mode, residual hearing, and receptive language abilities were explored. Pre- and post-implant speech perception scores were ... περισσότερα »
Bone Quality at the Sites of Loosened Screws in Mandibular Reconstruction Plates
Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 2 ώρες
[image: image]No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1MjiGX4 via IFTTT
Fractional Skin Harvesting: Autologous Skin Grafting without Donor-site Morbidity
Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 2 ώρες
[image: image]Background: Conventional autologous skin grafts are associated with significant donor-site morbidity. This study was conducted to determine feasibility, safety, and efficacy of a new strategy for skin grafting based on harvesting small columns of full-thickness skin with minimal donor-site morbidity. Methods: The swine model was used for this study. Hundreds of full-thickness columns of skin tissue (~700 µm diameter) were harvested using a custom-made harvesting device, and then applied directly to excisional skin wounds. Healing in donor and graft sites was evaluated ... περισσότερα »
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