British Journal of Oral and Maxillofacial Surgery
Association between p53 status, human papillomavirus infection, and overall survival in advanced oral cancer after resection and combination systemic treatment Publication date: Available online 6 December 2015 *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Tommaso Cutilli, Pietro Leocata, Vincenza Dolo, Emma Altobelli Our previous study on 75 cases of advanced oral squamous cell carcinomas (SCC) treated by neoadjuvant chemotherapy, radical surgery, and radiotherapy showed that overexpression of p53 of more than 50% indicated a strong probability of genetic mut...περισσότερα »
Transconjunctival and lateral canthotomy with modified endaural approaches in midface osteogenic distraction
Combination of via British Journal of Oral and Maxillofacial Surgery [image: The transconjunctival with lateral canthotomy approach, and the lateral orbital ...] [image: Diagram showing surgical approaches (green lines), Le Fort III osteotomies (red ...] [image: (A) Postoperative picture showing osteogenic distractors in place and adequate ...] [image: Preoperative and postoperative pictures showing changes after distraction and ...] *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Humberto Fernández-Olarte, Andrés Gómez-Delgado, Daniel Varón-Cardona, Sergio Truj... περισσότερα »
The antimicrobial effect of gaseous ozone compared to conventional methods against Enterococcus faecalis
Effect of gaseous ozone on Enterococcus faecalis biofilm–an in vitro study: Abstract ObjectivesThe aim of this study was to evaluate the antimicrobial effect of gaseous ozone compared to conventional methods against *Enterococcus faecalis.* Materials and methodsOne hundred twenty-five teeth were infected by *E. faecalis* and were incubated for 72 h to form biofilm. Teeth were distributed among five groups. In the first group, ozone was used; in the second group, teeth were rinsed with 20 % ethylenediaminetetraacetic acid (EDTA); in the third group, with 3 % sodium hypochlorite ... περισσότερα »
The impact of malocclusions on oral health-related quality of life in children
The impact of malocclusions on oral health-related quality of life in children—a systematic review and meta-analysis: Abstract IntroductionA limited amount of systematic literature reviews on the association between malocclusions and oral health-related quality of life (OHRQOL) summarize inconclusive results. Therefore, we conduct a systematic review and meta-analysis on the association of malocclusions with OHRQOL in children. MethodsRelevant studies were identified in Pubmed, Embase, Cochrane, Google Scholar and other databases. All studies with data on malocclusions or ortho...περισσότερα »
Factors affecting survival following self-inflicted head and neck gunshot wounds: a single-centre retrospective review
Factors affecting survival following self-inflicted head and neck gunshot wounds: a single-centre retrospective review: Abstract Self-inflicted head and neck gunshot wounds are a common modality of suicide in the USA. This study reviewed all self-inflicted head and neck gunshot wound patients with complete records (*n* = 157) treated at a tertiary centre between 2002 and 2012 inclusive. The associations between mortality and patient/clinical variables were evaluated with the *χ*2 test or Fisher's exact test for statistical difference testing. Outcomes recorded were death (*n* = 9... περισσότερα »
Long-term patterns of relapse and survival following definitive intensity-modulated radiotherapy for non-endemic nasopharyngeal carcinoma
Long-term patterns of relapse and survival following definitive intensity-modulated radiotherapy for non-endemic nasopharyngeal carcinoma: Intensity-modulated radiotherapy has developed into the standard definitive treatment for nasopharyngeal carcinoma over the past 15years, in both the United States and in Asia, where Epstein-Barr virus-related non-keratinizing carcinomas of the nasopharynx are endemic [1,2]. Three randomized trials have compared IMRT to conventional radiotherapy in the treatment of NPC [3–5]. Although local control rates with IMRT have improved with the advent an... περισσότερα »
MicroRNA-31 upregulation predicts increased risk of progression of oral potentially malignant disorder
MicroRNA-31 upregulation predicts increased risk of progression of oral potentially malignant disorder: Oral squamous cell carcinoma (OSCC), which accounts for two-thirds of head and neck squamous cell carcinoma (HNSCC), is one of the most prevalent cancers worldwide. OSCC typically develops from oral potentially malignant disorder (OPMD) and is attributed to smoking, betel nut or tobacco chewing, and HPV infection. The most common type of OPMD is oral leukoplakia that histopathologically presents as hyperkeratosis, epithelial hyperplasia, or dysplasia. High-grade epithelial dysplas...περισσότερα »
Single-Dose of Submucosal Injection of Dexamethasone Affects the Post Operative QOL
Single-Dose of Submucosal Injection of Dexamethasone Affects the Post Operative Quality of Life After Third Molar Surgery: Abstract IntroductionThird molar surgery (TMS) became a routine, safe office procedure with generally predictable outcomes and relative low cost. It affects quality of life (QOL) of patients by causing considerable pain, swelling and trismus; by changing what people eat, their speech in the first few days after surgery. The purpose of the present study was to improve QOL of patient after lower TMS by injecting single dose 8 mg submucosal dexamethasone. Mate... περισσότερα »
Tracheotomietechniken
Tracheotomietechniken: ZusammenfassungDurch die flächendeckende Etablierung moderner Verfahren hat sich die Tracheotomie zu einem Routineeingriff in der Intensivmedizin entwickelt. Durch die Tracheotomie können negative Effekte einer prolongierten translaryngealen Intubation auf die Larynx- und Trachealschleimhaut bis hin zur Trachealstenose vermindert werden. Weiterhin wird die Langzeitbeatmung bei kritisch kranken Patienten erleichtert. Es gibt allerdings keine eindeutige Evidenz über den optimalen Zeitpunkt der Tracheotomie bei Intensivpatienten. Für die sichere und erfolgreiche...περισσότερα »
Many faces of REM sleep behavior disorder
Many faces of REM sleep behavior disorder: an editorial: Since the first description of rapid-eye movement sleep behavior disorder (RBD) as a REM parasomnia in 19861 the concept of RBD has been evolving. The initial concept of RBD being an idiopathic parasomnia began to change since the investigators who originally described this entity observed that 38% of their original cohort of 29 idiopathic RBD (iRBD) patients developed signs and symptoms of Parkinson's disease (PD) 10 years after the inital description.2 Since this publication the concept shifted dramatically from idiopathic t... περισσότερα »
The Journal of the Acoustical Society of America
Airgun inter-pulse noise field during a seismic survey in an Arctic ultra shallow marine environment seismic Low-frequency sound level in the Southern Indian Ocean sound Coding pitch differences in voiceless fricatives: Whispered relative to normal speech Intonation Underdetermined reverberant acoustic source separation using weighted full-rank nonnegative tensor models K Effects of voice style, noise level, and acoustic feedback on objective and subjective voice evaluations room acoustic Enhancing cell kill in vitro from hyperthermia through pre-sensitizing with ultrasound-stimulated ... περισσότερα »
Mastoid Dimensions in Children and Young Adults: Consequences for the Geometry of Transcutaneous Bone-Conduction Implants.
Mastoid Dimensions in Children and Young Adults: Consequences for the Geometry of Transcutaneous Bone-Conduction Implants.: Objectives: Bone-conduction implants (BCI) are available for adults and children who are aged 5 years or more. Because a transcutaneous bone-conduction implant introduced in 2013 does not completely fit into all adult mastoids, we investigated mastoid dimensions and the possibility of fitting the implant in children. Design: Computed tomography scans of 151 mastoids from 80 children and young adolescents from the age of 5 months to 20 years and 52 control masto...περισσότερα »
Audible Tinnitus
Audible 2 Tinnitus Review: Tinnitus, also known as ringing of the ears, can be one of the most frustrating physical problems a person can deal with in their lives. With doctors having few answers as to what causes it and why it seems to come and go at times, patients with this condition can get frustrated to say the least. As with most other physical problems people face, there are those who claim to offer solutions to their problems, and tinnitus is no exception. One of the latest products to come along claiming to have the answers to combat tinnitus is the Audible 2, a type of hea... περισσότερα »
Age and gender differences in children and adolescents’ attitudes toward noise
Age and gender differences in children and adolescents’ attitudes toward noise Abstract *Objective*: Most school-aged children experience exposure to hazardous sound levels via high-risk noise activities (e.g. loud music/concerts, firearms). Little information exists regarding factors influencing pediatric engagement in these activities and use of hearing protection devices. This study explores effects of age, gender, and attitudes toward noise on participation in acoustic risk-taking behaviors and hearing conservation practices in children and adolescents. *Design*: Cross-secti... περισσότερα »
Prevalence and risk factors for reduced sound tolerance (hyperacusis) in children
Prevalence and risk factors for reduced sound tolerance (hyperacusis) in children Abstract *Objective*: To estimate the prevalence of reduced sound tolerance (hyperacusis) in a UK population of 11-year-old children and examine the association of early life and auditory risk factors with report of hyperacusis. *Design*: A prospective UK population-based study. *Study sample*: A total of 7097 eleven-year-old children within the Avon longitudinal study of parents and children (ALSPAC) were asked about sound tolerance; hearing and middle-ear function was measured using audiometry, o... περισσότερα »
Effect of Triple Combination of Induction, Concurrent and Adjuvant Chemotherapy in High Risk Nasopharyngeal Carcinoma
Effect of Triple Combination of Induction, Concurrent and Adjuvant Chemotherapy in High Risk Nasopharyngeal Carcinoma: *Condition*: Nasopharyngeal Carcinoma *Interventions*: Drug: Cisplatin 1; Drug: Cisplatin 2; Drug: Docetaxel; Drug: Xeloda; Radiation: Intensity-modulated radiotherapy *Sponsors*: Sun Yat-sen University; Affiliated Tumor Hospital of Guangzhou Medical University; The First Affiliated Hospital of Guangzhou Medical University; The First Affiliated Hospital of Guangdong Pharmaceutical University ArmsAssigned InterventionsExperimental: IC plus CC ... περισσότερα »
Exercise Protocol of Multisensory Rehabilitation in Treatment of the Complaints Vestibular: Clinical Trial Random
Exercise Protocol of Multisensory Rehabilitation in Treatment of the Complaints Vestibular: Clinical Trial Random: *Condition*: Vestibular Diseases *Interventions*: Other: Intervention Group (IG); Other: Control Group (CG) *Sponsor*: Viviane de Souza Pinho Costa Vertigo, dizziness and imbalance are the main symptoms of vestibular dysfunction. They can lead to physical consequences, such as the reduction of postural control and falls, psychological and / or psychiatric consequences such as anxiety and depression, panic and cognitive changes, especially in the elderly. It ... περισσότερα »
Bullet in the Parapharyngeal Space
Ballistic Reconstruction of a Migrating Bullet in the Parapharyngeal Space: A 21-year-old male suffering from severe throat pain after being hit by a bullet in Syria claimed that he was shot through his eye and that the bullet subsequently descended behind his throat. Even though the first medical report stated that this course is implausible, meticulous workup provided evidence that the bullet might have entered the parapharyngeal space in a more cranial position than the one it was found eight months later. Our case highlights that bullets are able to move within the body, renderi... περισσότερα »
Head and neck adenoid cystic carcinoma
: A prospective multicenter REFCOR study of 95 cases via European Annals of Otorhinolaryngology, Head and Neck Diseases *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Meyers, B. Granger, P. Herman, F. Janot, R. Garrel, N. Fakhry, G. Poissonnet, B. Baujat ObjectivesTo describe the clinical, histological and therapeutic characteristics of a prospective multicenter series of 95 head and neck adenoid cystic carcinoma patients, and to determine any prognostic factors for disease-free survival.Patients and methodsNinety-five patients with adenoid cysti...περισσότερα »
Nocardia nova sphenoid sinusitis and infratemporal fossa abscess
Nocardia nova sphenoid sinusitis and infratemporal fossa abscess via European Annals of Otorhinolaryngology, Head and Neck Diseases Figures and tables 1. [image: CT scan confirming left ethmoid and sphenoid sinusitis.] 2. [image: a. Sinus CT scan showing an abscess in the left pterygoid muscles; b. CT scan, ...] *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Giordano, M. Cohen-Salmon, B. Joly, C. Maffiolo IntroductionNocardia sinusitis is exceptional, as a Medline search revealed only one published case. The authors report a case of ... περισσότερα »
A customer value analysis of Taiwan ice cream market: a means-end chain approach across consumption situations
In the highly competitive market, it is increasingly hard for ice cream stores to develop creative marketing strategies to retain existing customers and attract new ones. This study applies the means–end chain approach to identify the customer value, consequences, and attributes of ice cream and to suggest useful information for ice cream sellers to develop differential marketing strategies across various consumption situations (i.e. on a date, gathering with friends, craving for ice cream). This study conducted one-on-one in-depth interviews with participants. The interview conte... περισσότερα »
Symptomatic Perihepatic Fluid Collections After Hepatic Resection in the Modern Era
Abstract Background Improvements in liver surgery have led to decreased mortality rates. Symptomatic perihepatic collections (SPHCs) requiring percutaneous drainage remain a significant source of morbidity. Study Design A single institution's prospectively maintained hepatic resection database was reviewed to identify patients who underwent hepatectomy between January 2004 and February 2012. Results Data from 2173 hepatectomies performed in 2040 patients were reviewed. Overall, 200 (9 %) patients developed an SPHC, the majority non-bilious (75.5 %) and infected (54 %). Major hep... περισσότερα »
Preliminary evaluation of exome sequencing to identify genetic markers of susceptibility to tuberculosis disease
Background: Recent studies have shown that certain human genetic polymorphisms could be associated with susceptibility to tuberculosis (TB) infection and disease. Advances in next generation sequencing include the ability to rapidly sequence the entire human exome. These new technologies can be exploited to identify new associations of human genetic polymorphisms and TB infection and disease. In this preliminary study we compared two different strategies for sequencing of the human exome in a small sample set consisting of three individuals with a history of TB disease and two ind...περισσότερα »
Ileal J-Pouch Volvulus Following Total Proctocolectomy for Ulcerative Colitis
Abstract Total proctocolectomy with ileal pouch-anal anastomosis (IPAA) allows restoration of continence in select patients with ulcerative colitis but is associated with significant morbidity. Well-known complications following IPAA include pouchitis, anastomotic leak, and small bowel obstruction. Obstruction secondary to ileal pouch volvulus is exceedingly rare. We report a case of ileal pouch volvulus, which occurred secondary to internal hernia. Radiographic and endoscopic identification of volvulus allowed for early operative management and pouch salvage. from Uncategorized ... περισσότερα »
Outcome of therapeutic penetrating keratoplasty
Bajracharya L, Gurung R from Medicine via xlomafota13 on Inoreader http://ift.tt/1R6cGBp via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1IBhaNP via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1QbJhpk via IFTTT
Ocular hypertension and hypotony in uveitis
Aman R, Engelhard SB, Bajwa A, Patrie J, Reddy AK from Medicine via xlomafota13 on Inoreader http://ift.tt/1RB8WqV via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TxnWoo via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1QbJh91 via IFTTT
Effect of specimen type on free immunoglobulin light chains analysis on the Roche Diagnostics cobas 8000 analyzer
The measurement of free immunoglobulin light chains is typically performed on serum; however, the use of alternative specimen types has potential benefits. Using the Freelite™ kappa and lambda free light chains assay on a Roche Diagnostics cobas 8000 c502 analyzer, we compared three specimen types (serum, EDTA-plasma and lithium heparin plasma separator gel-plasma) on 100 patients. Using Deming regression and eliminating outliers (limiting data to light chain concentrations below 400 mg/L), the three specimen types showed comparable results for kappa light chain concentration, lamb... περισσότερα »
A customer value analysis of Taiwan ice cream market: a means-end chain approach across consumption situations
In the highly competitive market, it is increasingly hard for ice cream stores to develop creative marketing strategies to retain existing customers and attract new ones. This study applies the means–end chain approach to identify the customer value, consequences, and attributes of ice cream and to suggest useful information for ice cream sellers to develop differential marketing strategies across various consumption situations (i.e. on a date, gathering with friends, craving for ice cream). This study conducted one-on-one in-depth interviews with participants. The interview conte... περισσότερα »
Symptomatic Perihepatic Fluid Collections After Hepatic Resection in the Modern Era
Abstract Background Improvements in liver surgery have led to decreased mortality rates. Symptomatic perihepatic collections (SPHCs) requiring percutaneous drainage remain a significant source of morbidity. Study Design A single institution's prospectively maintained hepatic resection database was reviewed to identify patients who underwent hepatectomy between January 2004 and February 2012. Results Data from 2173 hepatectomies performed in 2040 patients were reviewed. Overall, 200 (9 %) patients developed an SPHC, the majority non-bilious (75.5 %) and infected (54 %). Major hep... περισσότερα »
Choice of reference-guided sequence assembler and SNP caller for analysis of Listeria monocytogenes short-read sequence data greatly influences rates of error
Background: The influences that different programs and conditions have on error rates of single-nucleotide polymorphism (SNP) analyses are poorly understood. Using Illumina short-read sequence data generated from Listeria monocytogenes strain HPB5622, we assessed the performance of four SNP callers (BCFtools, FreeBayes, UnifiedGenotyper, VarScan) under a variety of conditions, including: (1) a range of sequencing coverages; (2) use of four popular reference-guided assemblers (Burrows-Wheeler Aligner, Novoalign, MOSAIK, SMALT); (3) with and without read quality trimming and filterin...περισσότερα »
Circular Stapler-Assisted Extraperitoneal Colostomy in Laparoscopic Abdominoperineal Resection: a Single Surgeon Experience
Abstract Background Nowadays, laparoscopic abdominoperineal resection (LAPR) not only has the same oncologic safety of open surgery and but also has the common advantages of laparoscopic surgery. However, given the difficulty in operation and long operative time, laparoscopic extraperitoneal colostomy construction is rarely practiced and reported. In this study, we describe technique of extraperitoneal colostomy using circular stapler following LAPR and demonstrate its efficacy and safety. Methods This is a retrospective analysis of prospectively maintained data of 42 patients wh... περισσότερα »
Morbid Obesity is Associated with Increased Mortality, Surgical Complications, and Incremental Health Care Utilization in the Peri-Operative Period of Colorectal Cancer Surgery
Abstract Background Morbid obesity (Basic Mass Index ≥ 40 kg/m2) leads to increased long-term mortality after colorectal cancer (CRC) surgery. Little is known about its effects on peri-operative CRC surgery outcomes. Methods 85,300 discharges for CRC surgery were identified using the redesigned 2012 National Inpatient Sample. Outcomes of interest were mortality, healthcare charges, and surgical outcomes in morbidly obese patients which were compared to those in nonobese patients. Results There were 4385 (5.14%) morbidly obese patients who underwent CRC surgery during the study p... περισσότερα »
Surgical Endoscopic Vacuum Therapy for Defects of the Upper Gastrointestinal Tract
Abstract Introduction Intraluminal therapy used in the gastrointestinal (GI) tract was first shown for anastomotic leaks after rectal resection. Since a few years vacuum sponge therapy is increasingly being recognized as a new promising method for repairing upper GI defects of different etiology. The principles of vacuum-assisted closure (VAC) therapy remain the same no matter of localization: Continuous or intermittent suction and drainage decrease bacterial contamination, secretion, and local edema. At the same time, perfusion and granulation is promoted. However, data for endosc... περισσότερα »
Antroduodenectomy with Gastroduodenal Anastomosis: Salvage Emergency Surgery for Complicated Peptic Ulcer Disease—Results of a Double Institution Study of 35 Patients
Abstract Background Endoscopic and interventional techniques are currently the mainstay of management of bleeding duodenal ulcer. As well, for patients with perforated duodenal ulcer, laparoscopic simple closure is nowadays usually performed. Although indications for emergency antroduodenectomy have declined, this procedure is still necessary as a salvage option when conservative management has failed or is not practicable. Our study aimed to evaluate indications and results of antroduodenectomy with gastroduodenal anastomosis in current practice and to examine the factors that pr...περισσότερα »
Activation of the SOS response increases the frequency of small colony variants
Background: In Staphylococcus aureus sub-populations of slow-growing cells forming small colony variants (SCVs) are associated with persistent and recurrent infections that are difficult to eradicate with antibiotic therapies. In SCVs that are resistant towards aminoglycosides, mutations have been identified in genes encoding components of the respiratory chain. Given the high frequencies of SCVs isolated clinically it is vital to understand the conditions that promote or select for SCVs. Results: In this study we have examined how exposure to sub-inhibitory concentrations of anti... περισσότερα »
A survey among Korea Medicine doctors (KMDs) in Korea on patterns of integrative Korean Medicine practice for lumbar intervertebral disc displacement: Preliminary research for clinical practice guidelines
Background: Patients seek Korean Medicine (KM) treatment for a broad range of complaints in Korea, but predominantly for musculoskeletal disorders. We investigated lumbar Intervertebral Disc Displacement (IDD) practice patterns of Korean Medicine doctors (KMDs) within a hospital/clinic network specializing in KM treatment of spinal disorders through survey of diagnosis and treatment methods. Methods: Questionnaires on clinical practice patterns of KM treatment for lumbar IDD were distributed to 149 KMDs on January 25th, 2015. The questionnaire included items on sociodemographic ch...περισσότερα »
Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) is the most prevalent leukemia among adults. Although chemoimmunotherapy prolongs the duration of remission and overall survival among most patients with CLL, relapse virtually always occurs. This has prompted aggressive discovery efforts for new therapies in CLL.… from Medicine via xlomafota13 on Inoreader http://ift.tt/1OeSGqg via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1IBh4Wx via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http:... περισσότερα »
Hospital Utilization of Nationally Shared Liver Allografts from 2007 to 2012
Abstract Background Due to the current geographic disparities in liver allocation a policy, which endorses broader sharing of allografts, has been proposed. We performed a retrospective cohort study to identify how nationally shared allografts, under the current policy, affect perioperative outcomes and resource utilization following liver transplantation (LT). Methods Univariate and multivariate analysis identified how patient characteristics and hospital outcomes were associated with national sharing. This analysis was based on 12,282 deceased donor liver transplants performed b... περισσότερα »
Post-Stroke Walking Behaviors Consistent with Altered Ground Reaction Force Direction Control Advise New Approaches to Research and Therapy
Abstract Recovery of walking after stroke requires an understanding of how motor control deficits lead to gait impairment. Traditional therapy focuses on removing specific observable gait behaviors that deviate from unimpaired walking; however, those behaviors may be effective compensations for underlying problematic motor control deficits rather than direct effects of the stroke. Neurological deficits caused by stroke are not well understood, and thus, efficient interventions for gait rehabilitation likely remain unrealized. Our laboratory has previously characterized a post-strok... περισσότερα »
Measuring Phagosome pH by Ratiometric Fluorescence Microscopy
[image: 53402fig1.jpg] Phagosomal pH influences phagosome maturation, oxidant production, phagosomal killing as well as antigen presentation. Here we describe a ratiometric method for measuring time-course and endpoint pH changes in individual phagosomes in living phagocytes using fluorescence microscopy. from Medicine via xlomafota13 on Inoreader http://ift.tt/1OeSEid via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TxnVRf via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader h...περισσότερα »
Safety of Laparoscopic Pelvic Exenteration with Urinary Diversion for Colorectal Malignancies
Abstract Background Although the feasibility of laparoscopic surgery for colorectal cancer has been demonstrated, the safety of laparoscopic pelvic exenteration (PE) with urinary diversion for colorectal malignancies remains poorly studied. The present study aimed to examine the safety and feasibility of laparoscopic PE in patients with colorectal malignancies. Methods Thirty-one consecutive patients who underwent anterior or total PE with urinary diversion for colorectal malignancies between July 2004 and April 2015 at our institution were included in the study. Perioperative out...περισσότερα »
Massive odontoameloblastoma arising in the maxilla: a case report
IntroductionOdontoameloblastoma is an extremely rare mixed odontogenic tumor with both epithelial and mesenchymal components. The term odontoameloblastoma first appeared in the 1971 World Health Organization classification (Pindborg JJ., et al.) and is defined as "a neoplasm that includes odontogenic ectomesenchyme in addition to odontogenic epithelium that resembles an ameloblastoma in both structures and behavior." Because of the aggressive nature and risk of recurrence of the tumor, complete resection is essential. In this report, we describe an extremely rare case of a patient... περισσότερα »
Preliminary evaluation of exome sequencing to identify genetic markers of susceptibility to tuberculosis disease
Background: Recent studies have shown that certain human genetic polymorphisms could be associated with susceptibility to tuberculosis (TB) infection and disease. Advances in next generation sequencing include the ability to rapidly sequence the entire human exome. These new technologies can be exploited to identify new associations of human genetic polymorphisms and TB infection and disease. In this preliminary study we compared two different strategies for sequencing of the human exome in a small sample set consisting of three individuals with a history of TB disease and two ind...περισσότερα »
Ileal J-Pouch Volvulus Following Total Proctocolectomy for Ulcerative Colitis
Abstract Total proctocolectomy with ileal pouch-anal anastomosis (IPAA) allows restoration of continence in select patients with ulcerative colitis but is associated with significant morbidity. Well-known complications following IPAA include pouchitis, anastomotic leak, and small bowel obstruction. Obstruction secondary to ileal pouch volvulus is exceedingly rare. We report a case of ileal pouch volvulus, which occurred secondary to internal hernia. Radiographic and endoscopic identification of volvulus allowed for early operative management and pouch salvage. from Uncategorized ... περισσότερα »
Outcome of therapeutic penetrating keratoplasty
Bajracharya L, Gurung R from Medicine via xlomafota13 on Inoreader http://ift.tt/1R6cGBp via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1IBhaNP via IFTTT
Ocular hypertension and hypotony in uveitis
Aman R, Engelhard SB, Bajwa A, Patrie J, Reddy AK from Medicine via xlomafota13 on Inoreader http://ift.tt/1RB8WqV via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TxnWoo via IFTTT
Effect of specimen type on free immunoglobulin light chains analysis on the Roche Diagnostics cobas 8000 analyzer
The measurement of free immunoglobulin light chains is typically performed on serum; however, the use of alternative specimen types has potential benefits. Using the Freelite™ kappa and lambda free light chains assay on a Roche Diagnostics cobas 8000 c502 analyzer, we compared three specimen types (serum, EDTA-plasma and lithium heparin plasma separator gel-plasma) on 100 patients. Using Deming regression and eliminating outliers (limiting data to light chain concentrations below 400 mg/L), the three specimen types showed comparable results for kappa light chain concentration, lamb... περισσότερα »
A customer value analysis of Taiwan ice cream market: a means-end chain approach across consumption situations
In the highly competitive market, it is increasingly hard for ice cream stores to develop creative marketing strategies to retain existing customers and attract new ones. This study applies the means–end chain approach to identify the customer value, consequences, and attributes of ice cream and to suggest useful information for ice cream sellers to develop differential marketing strategies across various consumption situations (i.e. on a date, gathering with friends, craving for ice cream). This study conducted one-on-one in-depth interviews with participants. The interview conte... περισσότερα »
Symptomatic Perihepatic Fluid Collections After Hepatic Resection in the Modern Era
Abstract Background Improvements in liver surgery have led to decreased mortality rates. Symptomatic perihepatic collections (SPHCs) requiring percutaneous drainage remain a significant source of morbidity. Study Design A single institution's prospectively maintained hepatic resection database was reviewed to identify patients who underwent hepatectomy between January 2004 and February 2012. Results Data from 2173 hepatectomies performed in 2040 patients were reviewed. Overall, 200 (9 %) patients developed an SPHC, the majority non-bilious (75.5 %) and infected (54 %). Major hep... περισσότερα »
Choice of reference-guided sequence assembler and SNP caller for analysis of Listeria monocytogenes short-read sequence data greatly influences rates of error
Background: The influences that different programs and conditions have on error rates of single-nucleotide polymorphism (SNP) analyses are poorly understood. Using Illumina short-read sequence data generated from Listeria monocytogenes strain HPB5622, we assessed the performance of four SNP callers (BCFtools, FreeBayes, UnifiedGenotyper, VarScan) under a variety of conditions, including: (1) a range of sequencing coverages; (2) use of four popular reference-guided assemblers (Burrows-Wheeler Aligner, Novoalign, MOSAIK, SMALT); (3) with and without read quality trimming and filterin...περισσότερα »
Circular Stapler-Assisted Extraperitoneal Colostomy in Laparoscopic Abdominoperineal Resection: a Single Surgeon Experience
Abstract Background Nowadays, laparoscopic abdominoperineal resection (LAPR) not only has the same oncologic safety of open surgery and but also has the common advantages of laparoscopic surgery. However, given the difficulty in operation and long operative time, laparoscopic extraperitoneal colostomy construction is rarely practiced and reported. In this study, we describe technique of extraperitoneal colostomy using circular stapler following LAPR and demonstrate its efficacy and safety. Methods This is a retrospective analysis of prospectively maintained data of 42 patients wh... περισσότερα »
Morbid Obesity is Associated with Increased Mortality, Surgical Complications, and Incremental Health Care Utilization in the Peri-Operative Period of Colorectal Cancer Surgery
Abstract Background Morbid obesity (Basic Mass Index ≥ 40 kg/m2) leads to increased long-term mortality after colorectal cancer (CRC) surgery. Little is known about its effects on peri-operative CRC surgery outcomes. Methods 85,300 discharges for CRC surgery were identified using the redesigned 2012 National Inpatient Sample. Outcomes of interest were mortality, healthcare charges, and surgical outcomes in morbidly obese patients which were compared to those in nonobese patients. Results There were 4385 (5.14%) morbidly obese patients who underwent CRC surgery during the study p... περισσότερα »
Surgical Endoscopic Vacuum Therapy for Defects of the Upper Gastrointestinal Tract
Abstract Introduction Intraluminal therapy used in the gastrointestinal (GI) tract was first shown for anastomotic leaks after rectal resection. Since a few years vacuum sponge therapy is increasingly being recognized as a new promising method for repairing upper GI defects of different etiology. The principles of vacuum-assisted closure (VAC) therapy remain the same no matter of localization: Continuous or intermittent suction and drainage decrease bacterial contamination, secretion, and local edema. At the same time, perfusion and granulation is promoted. However, data for endosc... περισσότερα »
Antroduodenectomy with Gastroduodenal Anastomosis: Salvage Emergency Surgery for Complicated Peptic Ulcer Disease—Results of a Double Institution Study of 35 Patients
Abstract Background Endoscopic and interventional techniques are currently the mainstay of management of bleeding duodenal ulcer. As well, for patients with perforated duodenal ulcer, laparoscopic simple closure is nowadays usually performed. Although indications for emergency antroduodenectomy have declined, this procedure is still necessary as a salvage option when conservative management has failed or is not practicable. Our study aimed to evaluate indications and results of antroduodenectomy with gastroduodenal anastomosis in current practice and to examine the factors that pr...περισσότερα »
Activation of the SOS response increases the frequency of small colony variants
Background: In Staphylococcus aureus sub-populations of slow-growing cells forming small colony variants (SCVs) are associated with persistent and recurrent infections that are difficult to eradicate with antibiotic therapies. In SCVs that are resistant towards aminoglycosides, mutations have been identified in genes encoding components of the respiratory chain. Given the high frequencies of SCVs isolated clinically it is vital to understand the conditions that promote or select for SCVs. Results: In this study we have examined how exposure to sub-inhibitory concentrations of anti... περισσότερα »
A survey among Korea Medicine doctors (KMDs) in Korea on patterns of integrative Korean Medicine practice for lumbar intervertebral disc displacement: Preliminary research for clinical practice guidelines
Background: Patients seek Korean Medicine (KM) treatment for a broad range of complaints in Korea, but predominantly for musculoskeletal disorders. We investigated lumbar Intervertebral Disc Displacement (IDD) practice patterns of Korean Medicine doctors (KMDs) within a hospital/clinic network specializing in KM treatment of spinal disorders through survey of diagnosis and treatment methods. Methods: Questionnaires on clinical practice patterns of KM treatment for lumbar IDD were distributed to 149 KMDs on January 25th, 2015. The questionnaire included items on sociodemographic ch...περισσότερα »
Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) is the most prevalent leukemia among adults. Although chemoimmunotherapy prolongs the duration of remission and overall survival among most patients with CLL, relapse virtually always occurs. This has prompted aggressive discovery efforts for new therapies in CLL.… from Medicine via xlomafota13 on Inoreader http://ift.tt/1OeSGqg via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1IBh4Wx via IFTTT
Hospital Utilization of Nationally Shared Liver Allografts from 2007 to 2012
Abstract Background Due to the current geographic disparities in liver allocation a policy, which endorses broader sharing of allografts, has been proposed. We performed a retrospective cohort study to identify how nationally shared allografts, under the current policy, affect perioperative outcomes and resource utilization following liver transplantation (LT). Methods Univariate and multivariate analysis identified how patient characteristics and hospital outcomes were associated with national sharing. This analysis was based on 12,282 deceased donor liver transplants performed b... περισσότερα »
Post-Stroke Walking Behaviors Consistent with Altered Ground Reaction Force Direction Control Advise New Approaches to Research and Therapy
Abstract Recovery of walking after stroke requires an understanding of how motor control deficits lead to gait impairment. Traditional therapy focuses on removing specific observable gait behaviors that deviate from unimpaired walking; however, those behaviors may be effective compensations for underlying problematic motor control deficits rather than direct effects of the stroke. Neurological deficits caused by stroke are not well understood, and thus, efficient interventions for gait rehabilitation likely remain unrealized. Our laboratory has previously characterized a post-strok... περισσότερα »
Measuring Phagosome pH by Ratiometric Fluorescence Microscopy
[image: 53402fig1.jpg] Phagosomal pH influences phagosome maturation, oxidant production, phagosomal killing as well as antigen presentation. Here we describe a ratiometric method for measuring time-course and endpoint pH changes in individual phagosomes in living phagocytes using fluorescence microscopy. from Medicine via xlomafota13 on Inoreader http://ift.tt/1OeSEid via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TxnVRf via IFTTT
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου