Antiemetic Therapy for Cancer Patients
State of the Art Antiemetic Therapy for Cancer Patients: AbstractNausea and vomiting are common in cancer patients. The most common cause of nausea and vomiting is the administration of cytotoxic chemotherapy. Apart from chemotherapy-induced nausea and vomiting (CINV), biological agents may also cause these symptoms. In this review, discussion will be focused on management of nausea and vomiting due to antineoplastic therapies. The cornerstone of effective management of nausea and vomiting secondary to these antineoplastic drugs is the prevention with the use of appropriate guideli...περισσότερα »
The pharmacokinetics of high-dose methotrexate
The pharmacokinetics of high-dose methotrexate in people living with HIV on antiretroviral therapy: Abstract PurposeClinical outcomes for lymphoma in people living with HIV (PLWH) are similar to those in the general public. However, a number of concerns remain including pharmacological interactions between cytotoxic chemotherapy and antiretroviral therapy (ARVs). Much attention has focussed on pharmacokinetic interactions attributable to effects on hepatic microsomal enzymes, but not on competition for the renal organic anion transport system. High-dose (3 g/m2) intravenous methot... περισσότερα »
Characterization of a new highly sensitive immunometric assay for thyroglobulin with reduced interference from autoantibodies
Characterization of a new highly sensitive immunometric assay for thyroglobulin with reduced interference from autoantibodies: AbstractMeasurements of serum thyroglobulin (Tg) with sensitive immunoassays are of great importance for the management of patients with differentiated thyroid carcinomas. However, interference of circulating autoantibodies to Tg (hTgAb) hampers the usefulness of most assays. We have produced a panel of monoclonal antibodies (mAbs) selected to bind Tg in the presence of Tg autoantibodies and developed a sensitive immunoassay for Tg with minor interference b...περισσότερα »
microRNA-137 is downregulated in thyroid cancer and inhibits proliferation and invasion by targeting EGFR
microRNA-137 is downregulated in thyroid cancer and inhibits proliferation and invasion by targeting EGFR: AbstractmicroRNA-137 expression is downregulated in several tumors. To date, its expression and function in human thyroid cancer remain unexplored. The aim of this study is to identify its expression, function, and molecular mechanism in thyroid cancer. microRNA-137 (miR-137) downregulation was observed in thyroid cancer tissues compared with normal thyroid tissues. miR-137 mimics downregulated B-CPAP cell proliferation, colony formation ability, and invasion, with suppressed ... περισσότερα »
Exposure to Low Aluminum Levels in Brain Regions
Silicon Reverses Lipid Peroxidation but not Acetylcholinesterase Activity Induced by Long-Term Exposure to Low Aluminum Levels in Rat Brain Regions: AbstractAluminum (Al) is the most widely distributed metal in the environment and is extensively used in daily life leading to easy exposure to human beings. Besides not having a recognized physiological role, Al may produce adverse effects through the interaction with the cholinergic system contributing to oxidative stress. The present study evaluated, in similar conditions of parenteral nutrition, whether the reaction of silicon (SiO2... περισσότερα »
The Protective Effect of Bafilomycin A1 Against Cobalt Nanoparticle-Induced Cytotoxicity and Aseptic Inflammation in Macrophages In Vitro
The Protective Effect of Bafilomycin A1 Against Cobalt Nanoparticle-Induced Cytotoxicity and Aseptic Inflammation in Macrophages In Vitro: AbstractCo ions released due to corrosion of Co nanoparticles (CoNPs) in the lysosomes of macrophages may be a factor in the particle-induced cytotoxicity and aseptic inflammation accompanying metal-on-metal (MOM) hip prosthesis failure. Here, we show that CoNPs are easily dissolved under a low pH, simulating the acidic lysosomal environment. We then used bafilomycin A1 to change the pH inside the lysosome to inhibit intracellular corrosion of C... περισσότερα »
Copper-Induced Inactivation of Camel Liver Glutathione S -Transferase
Copper-Induced Inactivation of Camel Liver Glutathione S -Transferase: AbstractGlutathione *S*-transferases (GSTs) are multifunctional enzymes and play an important role in detoxification of xenobiotics and protection against oxidative stress. Camel liver glutathione transferase (cGST) was recently isolated and characterized in our lab. In this study, we have evaluated the effect of monovalent, divalent, and trivalent cations on its activity and stability. Cu++ was found to be the potent inhibitor of GST activity which loses complete activity at 0.5-mM concentration. Other metal io... περισσότερα »
Photothermal cancer therapy by gold-ferrite nanocomposite and near-infrared laser in animal model
Photothermal cancer therapy by gold-ferrite nanocomposite and near-infrared laser in animal model: AbstractSurface plasmon resonance effect of gold nanostructures makes them good candidates for photothermal therapy (PTT) application. Herein, gold-ferrite nanocomposite (GFNC) was synthesized and characterized as a photothermal agent in PTT. The aim of this study was to investigate the effect of GFNC upon laser irradiation on treatment of cancer in mice bearing melanoma cancer. Thirty mice received 1.5 × 106 B16/F10 cells subcutaneously. After 1 week, the mice bearing solid tumor wer...περισσότερα »
Laser-assisted drug delivery in dermatology
Laser-assisted drug delivery in dermatology: from animal models to clinical practice: AbstractTopical medicaments are the mainstay of the dermatologists’ therapeutic arsenal. Laser-assisted drug delivery enhances the ability of topically applied medicaments to penetrate the skin. We discuss the mechanisms of laser-assisted drug delivery and animal models that have informed clinical practice. We review clinical studies that have employed laser-assisted drug delivery for a range of indications to date including non-melanoma skin cancer, vitiligo, scarring, vaccination, local anaesth... περισσότερα »
Large Septal Perforation Repair with Pericranial Flap and Intraoperative Fluorescence Angiography
Large Septal Perforation Repair with Pericranial Flap and Intraoperative Fluorescence Angiography: Cranial Maxillofac Trauma Reconstruction DOI: 10.1055/s-0035-1570073 Septal perforations present a challenging dilemma for surgical intervention when medical therapy fails. Multiple techniques have been described in the literature to address perforations using numerous techniques; however, there have been varying rates of success and reproducibility reported. The use of a large, pericranial flap was previously described to repair large septal perforation. The objective of this case r... περισσότερα »
Burning mouth syndrome (BMS) : 2% topical chamomile application
Effect of a 2% topical chamomile application for treating burning mouth syndrome: a controlled clinical trial: Background The treatments for burning mouth syndrome (BMS) proposed to date have been varied but have only achieved limited efficacy. Chamomile has analgesic and anti-inflammatory properties. The aim of this study was to evaluate the efficacy of topical applications of 2% chamomile gel in comparison with a placebo for the treatment of BMS. Materials and methods The study was designed as a prospective randomized placebo-controlled double-blind monocentric study. A total of 6... περισσότερα »
Role of distinct CD4+ T helper subset in pathogenesis of oral lichen planus
Role of distinct CD4+ T helper subset in pathogenesis of oral lichen planus: Oral lichen planus (OLP) is one of the most common chronic inflammatory oral mucosal diseases with T-cell-mediated immune pathogenesis. In subepithelial and lamina propria of OLP local lesions, the presence of CD4+ T helper (CD4+ Th) cells appeared as the major lymphocytes. These CD4+ T lymphocytes can differentiate into distinct Th cell types such as Th1, Th2, Treg, Th17, Th22, Th9, and Tfh within the context of certain cytokines environment. Growing evidence indicated that Th1/Th2 imbalance may greatly ...περισσότερα »
Matrix metalloproteinases in ameloblastomas
Immunohistochemical expression of matrix metalloproteinases in ameloblastomas and pericoronal follicles: Background Ameloblastoma (AM) is a benign odontogenic neoplasm characterized by local invasiveness and recurrence. We compared the immunohistochemical expression of matrix metalloproteinases in different clinical types of AM as well as in normal odontogenic tissue. Methods Thirteen cases of solid AMs, five cases of unicystic AM and eight pericoronal follicles (PF) were selected and subjected to immunohistochemical investigation for matrix metalloproteinase-1, matrix metalloprote...περισσότερα »
Melatonin localization in human salivary glands
Melatonin localization in human salivary glands by Michela Isola, Maria Alberta Lilliu via Oral Pathology & Medicine Background Circulating melatonin is believed to reach body fluids by crossing passively the cell membranes, but alternative ways for melatonin transport also are hypothesized. This investigation was carried out to furnish ultrastructural evidences for melatonin transport by salivary gland cells in order to indicate plausible routes by which circulating melatonin can reach saliva. Methods Bioptic samples of parotid, submandibular and labial glands were processed for the ... περισσότερα »
Salivary malondialdehyde in assessment of oxidative stress
Role of salivary malondialdehyde in assessment of oxidative stress among diabetics via ScienceDirect Publication: Journal of Oral Biology and Craniofacial Research Publication date: Available online 22 December 2015 *Source:*Journal of Oral Biology and Craniofacial Research Author(s): Komal Smriti, Keerthilatha Muralidhar Pai, Vineetha Ravindranath, Kalyana Chakravarthy Pentapati AimsTo evaluate and compare the salivary content of malondialdehyde (MDA) in patients with type 2 diabetes and control subjects.MethodsWe conducted a cross-sectional study among 30 freshly diagnosed subjects o...περισσότερα »
Thyroglossal duct surgery,Sistrunk procedure
Thyroglossal duct surgery. Sistrunk procedure via European Annals of Otorhinolaryngology, Head and Neck Diseases Publication date: Available online 22 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): C.-A. Righini, A. Hitter, E. Reyt, I. Atallah Midline cysts of the neck are the most common congenital malformations of the neck. They arise along the thyroglossal duct. The presence of a fistula is the result of either spontaneous (suppuration) or surgical fistulisation (simple incision or incomplete excision). The cyst and/or fistula are loc...περισσότερα »
Corrigendum
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 10 δευτερόλεπτα
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Corrigendum
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 10 δευτερόλεπτα
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Table of Contents
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 10 δευτερόλεπτα
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Editorial Board
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 10 δευτερόλεπτα
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1PjW9H1 via IFTTT
Thyroglossal duct surgery. Sistrunk procedure
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 11 δευτερόλεπτα
Publication date: Available online 22 December 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): C.-A. Righini, A. Hitter, E. Reyt, I. Atallah Midline cysts of the neck are the most common congenital malformations of the neck. They arise along the thyroglossal duct. The presence of a fistula is the result of either spontaneous […]
Role of salivary malondialdehyde in assessment of oxidative stress among diabetics
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 11 δευτερόλεπτα
Publication date: Available online 22 December 2015 Source:Journal of Oral Biology and Craniofacial Research Author(s): Komal Smriti, Keerthilatha Muralidhar Pai, Vineetha Ravindranath, Kalyana Chakravarthy Pentapati AimsTo evaluate and compare the salivary content of malondialdehyde (MDA) in patients with type 2 diabetes and control subjects.MethodsWe conducted a cross-sectional study among 30 freshly diagnosed subjects of diabetes […]
Impact of cancer anorexia-cachexia syndrome on health-related quality of life and resource utilisation: A systematic review
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 11 δευτερόλεπτα
Publication date: Available online 22 December 2015 Source:Critical Reviews in Oncology/Hematology Author(s): Rosanna Tarricone, Giada Ricca, Barbara Nyanzi-Wakholi, Antonieta Medina-Lara IntroductionCancer anorexia-cachexia syndrome (CACS) negatively impacts patients’ quality of life (QoL) and increases the burden on healthcare resources.ObjectivesTo review published CACS data regarding health-related QOL (HRQoL) and its economic impact on the healthcare system.MethodsSearches were […]
Eplerenone in the Treatment of Polypoidal Choroidal Vasculopathy
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 11 δευτερόλεπτα
Overactivation of mineralocorticoid receptor pathways has been implicated in the pathophysiology of central serous chorioretinopathy (CSCR). Recently, mineralocorticoid receptor antagonists such as eplerenone have demonstrated success in treating subretinal fluid in CSCR. This case demonstrates a patient who was initially presumed to have subretinal fluid secondary to CSCR and was started on a trial of […]
Issue Information – TOC
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 11 δευτερόλεπτα
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Issue Information – Journal Information
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 11 δευτερόλεπτα
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1MvDPpL via IFTTT
Role of salivary malondialdehyde in assessment of oxidative stress among diabetics
Publication date: Available online 22 December 2015 *Source:*Journal of Oral Biology and Craniofacial Research Author(s): Komal Smriti, Keerthilatha Muralidhar Pai, Vineetha Ravindranath, Kalyana Chakravarthy Pentapati AimsTo evaluate and compare the salivary content of malondialdehyde (MDA) in patients with type 2 diabetes and control subjects.MethodsWe conducted a cross-sectional study among 30 freshly diagnosed subjects of diabetes mellitus and 30 volunteers with no diabetes mellitus. Serum and salivary MDS levels were evaluated among all the subjects.ResultsThe mean serum MDA in...περισσότερα »
Editorial Board
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1PjW9H1 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZoUu7W via IFTTT
Thyroglossal duct surgery. Sistrunk procedure
Publication date: Available online 22 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): C.-A. Righini, A. Hitter, E. Reyt, I. Atallah Midline cysts of the neck are the most common congenital malformations of the neck. They arise along the thyroglossal duct. The presence of a fistula is the result of either spontaneous (suppuration) or surgical fistulisation (simple incision or incomplete excision). The cyst and/or fistula are located between the base of the tongue and the thyroid gland, predominantly adjacent to the hyoid bone. This midl...περισσότερα »
Role of salivary malondialdehyde in assessment of oxidative stress among diabetics
Publication date: Available online 22 December 2015 *Source:*Journal of Oral Biology and Craniofacial Research Author(s): Komal Smriti, Keerthilatha Muralidhar Pai, Vineetha Ravindranath, Kalyana Chakravarthy Pentapati AimsTo evaluate and compare the salivary content of malondialdehyde (MDA) in patients with type 2 diabetes and control subjects.MethodsWe conducted a cross-sectional study among 30 freshly diagnosed subjects of diabetes mellitus and 30 volunteers with no diabetes mellitus. Serum and salivary MDS levels were evaluated among all the subjects.ResultsThe mean serum MDA in...περισσότερα »
Demoralization Scale in Spanish-Speaking Palliative Care Patients
Among the approaches to the demoralization syndrome, the one proposed by Kissane et al. is prevalent in the literature. These authors developed the Demoralization Scale (DS) in order to assess emotional distress, conceived as demoralization. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFIZHR via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TgVgQK via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Ino...περισσότερα »
A systematic review of the impact of center volume in dialysis
Abstract Background A significant relationship exists between the volume of surgical procedures that a given center performs and subsequent outcomes. It seems plausible that such a volume–outcome relationship is also present in dialysis. Methods MEDLINE and EMBASE were searched in November 2014 for non-experimental studies evaluating the association between center volume and patient outcomes [mortality, morbidity, peritonitis, switch to hemodialysis (HD) or any other treatment], without language restrictions or other limits. Selection of relevant studies, data extraction and criti...περισσότερα »
Traumatic intrapericardial diaphragmatic hernia: findings on a computed tomography scan
from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1QWRoFe via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NLdMgm via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1IpHFWA via IFTTT
Demoralization Scale in Spanish-Speaking Palliative Care Patients
Among the approaches to the demoralization syndrome, the one proposed by Kissane et al. is prevalent in the literature. These authors developed the Demoralization Scale (DS) in order to assess emotional distress, conceived as demoralization. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFIZHR via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TgVgQH via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Ino...περισσότερα »
The diagnostic utility of 3D electroencephalography source imaging in pediatric epilepsy surgery
Summary Objective The aim of this study was to investigate the utility of three-dimensional electroencephalography source imaging (3D-ESI) with low-resolution electroencephalographic data in the pediatric noninvasive presurgical evaluation, and to compare the findings with positron emission tomography (PET) and ictal single-photon emission computed tomography (iSPECT). Methods We retrospectively selected 60 patients from a database of 594 patients who underwent excisional surgery for drug-resistant epilepsy. Patients were <18 years at time of surgery, had at least one presurgical...περισσότερα »
Pc-facs
PC-FACS (Fast Article Critical Summaries for Clinicians in Palliative Care) provides hospice and palliative care clinicians with concise summaries of the most important findings from more than 100 medical and scientific journals. If you have colleagues who would benefit from receiving PC-FACS, please encourage them to join the AAHPM at aahpm.org. Comments from readers are welcomed at pc-facs@aahpm.org. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFJ1PW via IFTTT from #Med Blogs by Alexandros G.S... περισσότερα »
Small heat shock proteins are induced during multiple sclerosis lesion development in white but not grey matter
The important protective role of small heat-shock proteins (HSPs) in regulating cellular survival and migration, counteracting protein aggregation, preventing apoptosis, and regulating inflammation in the cent… from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1V6ydck via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NLdMgi via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1IpHFGg via IFTTT
Tai Chi Exercise for Cancer-Related Fatigue in Patients with Lung Cancer Undergoing Chemotherapy: A Randomized Controlled Trial
Context. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1V6xt76 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1On4Fbd via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1IpHElC via IFTTT
Pc-facs
PC-FACS (Fast Article Critical Summaries for Clinicians in Palliative Care) provides hospice and palliative care clinicians with concise summaries of the most important findings from more than 100 medical and scientific journals. If you have colleagues who would benefit from receiving PC-FACS, please encourage them to join the AAHPM at aahpm.org. Comments from readers are welcomed at pc-facs@aahpm.org. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFJ1PW via IFTTT from #Med Blogs by Alexandros G.S... περισσότερα »
Tai Chi Exercise for Cancer-Related Fatigue in Patients with Lung Cancer Undergoing Chemotherapy: A Randomized Controlled Trial
Context. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1V6xt76 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1On4Fb9 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1IpHElv via IFTTT
Thyroglossal duct surgery. Sistrunk procedure
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Publication date: Available online 22 December 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): C.-A. Righini, A. Hitter, E. Reyt, I. Atallah Midline cysts of the neck are the most common congenital malformations of the neck. They arise along the thyroglossal duct. The presence of a fistula is the result of either spontaneous […]
Mitochondrial DNA hypomethylation in chrome plating workers
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Publication date: 22 January 2016 Source:Toxicology Letters, Volume 243 Author(s): Yang Linqing, Xia Bo, Yang Xueqin, Ding Hong, Wu Desheng, Zhang Huimin, Jiang Gaofeng, Liu Jianjun, Zhuang Zhixiong A matched case–control study was conducted to examine the relationship between chromium (Cr) exposure and variation in mitochondrial (mt) DNA methylation. We enrolled 29 pairs of subjects […]
Thyroglossal duct surgery. Sistrunk procedure
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Publication date: Available online 22 December 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): C.-A. Righini, A. Hitter, E. Reyt, I. Atallah Midline cysts of the neck are the most common congenital malformations of the neck. They arise along the thyroglossal duct. The presence of a fistula is the result of either spontaneous […]
Mitochondrial DNA hypomethylation in chrome plating workers
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Publication date: 22 January 2016 Source:Toxicology Letters, Volume 243 Author(s): Yang Linqing, Xia Bo, Yang Xueqin, Ding Hong, Wu Desheng, Zhang Huimin, Jiang Gaofeng, Liu Jianjun, Zhuang Zhixiong A matched case–control study was conducted to examine the relationship between chromium (Cr) exposure and variation in mitochondrial (mt) DNA methylation. We enrolled 29 pairs of subjects […]
Role of salivary malondialdehyde in assessment of oxidative stress among diabetics
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Publication date: Available online 22 December 2015 Source:Journal of Oral Biology and Craniofacial Research Author(s): Komal Smriti, Keerthilatha Muralidhar Pai, Vineetha Ravindranath, Kalyana Chakravarthy Pentapati AimsTo evaluate and compare the salivary content of malondialdehyde (MDA) in patients with type 2 diabetes and control subjects.MethodsWe conducted a cross-sectional study among 30 freshly diagnosed subjects of diabetes […]
The risk for developing cancer in israeli ATM, BLM, and FANCC heterozygous mutation carriers
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Publication date: Available online 22 December 2015 Source:Cancer Genetics Author(s): Yael Laitman, Lital Boker Keinan, Michal Berkenstadt, Irena Liphsitz, Daphna Weissglas-Volkov, Liat Ries-Levavi, Ifat Sarouk, Elon Pras, Eitan Friedman Cancer risks in heterozygous mutation carriers of the ATM, BLM and FANCC genes are controversial. To shed light on this issue, cancer rates were evaluated by […]
Optimal strategy for obtaining routine chromosome analysis by using negative fractions of CD138 enriched plasma cells
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Publication date: Available online 23 December 2015 Source:Cancer Genetics Author(s): Veronica Ortega, Gihan Mohamed, William Ehman, Meiqing Zhu, Christina Mendiola, Gopalrao Velagaleti Fluorescence in situ hybridization (FISH) is superior to routine chromosome analysis (RCA) in detecting important prognostic genetic abnormalities in plasma cell dyscrasia (PCD); however, its sensitivity is hampered due to paucity of plasma […]
A systematic review of the impact of center volume in dialysis
AbstractBackground A significant relationship exists between the volume of surgical procedures that a given center performs and subsequent outcomes. It seems plausible that such a volume–outcome relationship is also present in dialysis. Methods MEDLINE and EMBASE were searched in November 2014 for non-experimental studies evaluating the association between center volume and patient outcomes [mortality, morbidity, peritonitis, switch to hemodialysis (HD) or any other treatment], without language restrictions or other limits. Selection of relevant studies, data extraction and critical... περισσότερα »
Traumatic intrapericardial diaphragmatic hernia: findings on a computed tomography scan
from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1QWRoFe via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NLdMgm via IFTTT
The diagnostic utility of 3D electroencephalography source imaging in pediatric epilepsy surgery
Summary Objective The aim of this study was to investigate the utility of three-dimensional electroencephalography source imaging (3D-ESI) with low-resolution electroencephalographic data in the pediatric noninvasive presurgical evaluation, and to compare the findings with positron emission tomography (PET) and ictal single-photon emission computed tomography (iSPECT). Methods We retrospectively selected 60 patients from a database of 594 patients who underwent excisional surgery for drug-resistant epilepsy. Patients were <18 years at time of surgery, had at least one presurgical vo...περισσότερα »
Small heat shock proteins are induced during multiple sclerosis lesion development in white but not grey matter
The important protective role of small heat-shock proteins (HSPs) in regulating cellular survival and migration, counteracting protein aggregation, preventing apoptosis, and regulating inflammation in the cent… from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1V6ydck via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NLdMgi via IFTTT
Pc-facs
PC-FACS (Fast Article Critical Summaries for Clinicians in Palliative Care) provides hospice and palliative care clinicians with concise summaries of the most important findings from more than 100 medical and scientific journals. If you have colleagues who would benefit from receiving PC-FACS, please encourage them to join the AAHPM at aahpm.org. Comments from readers are welcomed at pc-facs@aahpm.org. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFJ1PW via IFTTT from #Med Blogs by Alexandros G.S... περισσότερα »
Pc-facs
PC-FACS (Fast Article Critical Summaries for Clinicians in Palliative Care) provides hospice and palliative care clinicians with concise summaries of the most important findings from more than 100 medical and scientific journals. If you have colleagues who would benefit from receiving PC-FACS, please encourage them to join the AAHPM at aahpm.org. Comments from readers are welcomed at pc-facs@aahpm.org. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFJ1PW via IFTTT from #Med Blogs by Alexandros G.S... περισσότερα »
Demoralization Scale in Spanish-Speaking Palliative Care Patients
Among the approaches to the demoralization syndrome, the one proposed by Kissane et al. is prevalent in the literature. These authors developed the Demoralization Scale (DS) in order to assess emotional distress, conceived as demoralization. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFIZHR via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TgVgQK via IFTTT
Tai Chi Exercise for Cancer-Related Fatigue in Patients with Lung Cancer Undergoing Chemotherapy: A Randomized Controlled Trial
Context. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1V6xt76 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1On4Fbd via IFTTT
Demoralization Scale in Spanish-Speaking Palliative Care Patients
Among the approaches to the demoralization syndrome, the one proposed by Kissane et al. is prevalent in the literature. These authors developed the Demoralization Scale (DS) in order to assess emotional distress, conceived as demoralization. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFIZHR via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TgVgQH via IFTTT
Tai Chi Exercise for Cancer-Related Fatigue in Patients with Lung Cancer Undergoing Chemotherapy: A Randomized Controlled Trial
Context. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1V6xt76 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1On4Fb9 via IFTTT
Recurrent nonspecific low back pain: Balance recovery reactions
Balance recovery reactions in individuals with recurrent nonspecific low back pain: Effect of attention via Gait & Posture Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Yasaman Etemadi, Mahyar Salavati, Amir M. Arab, Tabassom Ghanavati People who suffer from Low Back Pain (LBP) demonstrate impaired postural control. Deficits in sensory-motor systems have been proposed to be related to these changes. Considering higher cognitive process contribution to postural control, the aim of this study was to investigate the effects of cognitive load on balance con...περισσότερα »
Gait & Posture
The use of force-plate posturography in the assessment of postural instability Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Janusz W. Błaszczyk Force-plate posturography is a simple method that is commonly used in the contemporary laboratory and clinic to assess postural control. Despite the obvious advantages and popularity of the method, universal standards for posturographic tests have not been developed thus far: most postural assessments are based on the standard spatiotemporal metrics of the center-of-foot pressure (COP) recorded during quiet s... περισσότερα »
India ready for robotic surgeries to treat head, neck cancer: Top US surgeon … – Business Standard (press release) (registration) (blog)
*India ready for robotic surgeries to treat head, neck cancer: Top US surgeon …* *Business Standard (press release) (registration) (blog)* India has significant talent and expertise in traditional *head and neck* surgical procedures and the country is poised to take a giant leap with robot-assisted surgeries for *head and neck* patients in the days to come, a leading US robotic surgeon has said. *and more »* from ORL-Medicine by Sfakianakis via alwin on Inoreader http://ift.tt/1Ipv5H1 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader...περισσότερα »
Metastatic Renal Cell Carcinoma Presenting as Nasal Mass: Case Report and Review of Literature
Abstract Sinonasal neoplasms are rare and exceptional site for metastatic tumours and comprising <3 % of all malignant aerodigestive tumours and <1 % of all malignancies. Renal cell carcinoma is known to metastasise to the most unusual sites, the sinonasal region being one of them. We here by present a case of 60 year old male patient who presented with epistaxis and nasal obstruction. Clinical examination and CT scan revealed a tumour in the right nasal cavity and maxillary sinus. The presence of primary renal cell carcinoma was recognized only after surgical removal of metastatic ...περισσότερα »
Nasopharyngeal Stenosis: A Rare Radiotherapy Complication
AbstractIntroduction Acquired nasopharyngeal stenosis after radiotherapy for NPC is rare. We report a case of bilateral choanal stenosis and nasopharygeal stenosis in patient treated with chemo radiotherapy for undifferentieted nasopharnygeal carcinoma. Case Report A 68 years old man treated for undifferentiated nasopharyngeal carcinoma with chemo-radiotherapy 10 years before. He complained of complete nasal obstruction, rhinorrhea, anosmia, snoring and hearing loss. Clinical examination and imaging revealed bilateral choanal stenosis and nasopharyngeal stenosis. Patient underwent ...περισσότερα »
Melatonin localization in human salivary glands
Background Circulating melatonin is believed to reach body fluids by crossing passively the cell membranes, but alternative ways for melatonin transport also are hypothesized. This investigation was carried out to furnish ultrastructural evidences for melatonin transport by salivary gland cells in order to indicate plausible routes by which circulating melatonin can reach saliva. Methods Bioptic samples of parotid, submandibular and labial glands were processed for the electron microscopy and treated to demonstrate melatonin reactivity by the immunogold staining method. Results and... περισσότερα »
Role of distinct CD4+ T helper subset in pathogenesis of oral lichen planus
Oral lichen planus (OLP) is one of the most common chronic inflammatory oral mucosal diseases with T-cell-mediated immune pathogenesis. In subepithelial and lamina propria of OLP local lesions, the presence of CD4+ T helper (CD4+ Th) cells appeared as the major lymphocytes. These CD4+ T lymphocytes can differentiate into distinct Th cell types such as Th1, Th2, Treg, Th17, Th22, Th9, and Tfh within the context of certain cytokines environment. Growing evidence indicated that Th1/Th2 imbalance may greatly participate into the cytokine network of OLP immunopathology. In addition, Th...περισσότερα »
Immunohistochemical expression of matrix metalloproteinases in ameloblastomas and pericoronal follicles
Background Ameloblastoma (AM) is a benign odontogenic neoplasm characterized by local invasiveness and recurrence. We compared the immunohistochemical expression of matrix metalloproteinases in different clinical types of AM as well as in normal odontogenic tissue. Methods Thirteen cases of solid AMs, five cases of unicystic AM and eight pericoronal follicles (PF) were selected and subjected to immunohistochemical investigation for matrix metalloproteinase-1, matrix metalloproteinase-2 and matrix metalloproteinase-9 expressions. Results The expressions of MMP-1 and MMP-2 were very ... περισσότερα »
Sleep, mental status, and biological markers in saliva in patients with oral lichen planus
from ! ORL via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1V69SDH via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1IpwltJ via IFTTT
Effect of a 2% topical chamomile application for treating burning mouth syndrome: a controlled clinical trial
Background The treatments for burning mouth syndrome (BMS) proposed to date have been varied but have only achieved limited efficacy. Chamomile has analgesic and anti-inflammatory properties. The aim of this study was to evaluate the efficacy of topical applications of 2% chamomile gel in comparison with a placebo for the treatment of BMS. Materials and methods The study was designed as a prospective randomized placebo-controlled double-blind monocentric study. A total of 62 patients with idiopathic BMS were divided into two groups: Group A received applications of a 2% chamomile g...περισσότερα »
Age-related changes in postural sway in preschoolers
Age-related changes in postural sway in preschoolers via Gait & Posture Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Evi Verbecque, Paula Hentschel Lobo da Costa, Pieter Meyns, Kaat Desloovere, Luc Vereeck, Ann Hallemans ObjectivesThe present study aimed to investigate age-related differences of postural sway in 3- to 6-year-old typically developing children in different sensory conditions and subsequently to provide reference values for global descriptive sway parameters in preschoolers.MethodsNinety-six typically developing children, between 3 and 5 y... περισσότερα »
Empirical prediction of peak pressure levels in anthropogenic impulsive noise. Part I: Airgun arrays signals
Empirical prediction of peak pressure levels in anthropogenic impulsive noise. Part I: Airgun arrays signals: This paper presents an empirical linear equation to predict peak pressure level of anthropogenic impulsive signals based on its correlation with the sound exposure level. The regression coefficients are shown to be weakly dependent on the environmental characteristics but governed by the source type and parameters. The equation can be applied to values of the sound exposure level predicted with a numerical model, which provides a significant improvement in the prediction of ...περισσότερα »
Precedence based speech segregation in bilateral cochlear implant users
Precedence based speech segregation in bilateral cochlear implant users: The precedence effect (PE) enables the perceptual dominance by a source (lead) over an echo (lag) in reverberant environments. In addition to facilitating sound localization, the PE can play an important role in spatial unmasking of speech. Listeners attending to binaural vocoder simulations with identical channel center frequencies and phase demonstrated PE-based benefits in a closed-set speech segregation task. When presented with the same stimuli, bilateral cochlear implant users did not derive such benefits...περισσότερα »
Lexical and age effects on word recognition in noise
in normal-hearing children via International Journal of Pediatric Otorhinolaryngology Publication date: December 2015 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 79, Issue 12 Author(s): Cuncun Ren, Sha Liu, Haihong Liu, Ying Kong, Xin Liu, Shujing Li ObjectivesThe purposes of the present study were (1) to examine the lexical and age effects on word recognition of normal-hearing (NH) children in noise, and (2) to compare the word-recognition performance in noise to that in quiet listening conditions.MethodsParticipants were 213 NH children (age ranged betwee...περισσότερα »
Auditory neuropathy spectrum disorder (ANSD) and cochlear implantation
Auditory neuropathy spectrum disorder (ANSD) and cochlear implantation via International Journal of Pediatric Otorhinolaryngology Publication date: December 2015 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 79, Issue 12 Author(s): Robert V. Harrison, Karen A. Gordon, Blake C. Papsin, Jaina Negandhi, Adrian L. James We discuss issues related to cochlear implantation in children with auditory neuropathy spectrum disorder (ANSD). We describe the varied nature of this disease category including the numerous potential causes of auditory neuropathy. The most preval... περισσότερα »
Mitochondrial DNA hypomethylation in chrome plating workers
Publication date: 22 January 2016 Source:Toxicology Letters, Volume 243 Author(s): Yang Linqing, Xia Bo, Yang Xueqin, Ding Hong, Wu Desheng, Zhang Huimin, Jiang Gaofeng, Liu Jianjun, Zhuang Zhixiong A matched case–control study was conducted to examine the relationship between chromium (Cr) exposure and variation in mitochondrial (mt) DNA methylation. We enrolled 29 pairs of subjects… Continue reading Mitochondrial DNA hypomethylation in chrome plating workers
Role of salivary malondialdehyde in assessment of oxidative stress among diabetics
Publication date: Available online 22 December 2015 Source:Journal of Oral Biology and Craniofacial Research Author(s): Komal Smriti, Keerthilatha Muralidhar Pai, Vineetha Ravindranath, Kalyana Chakravarthy Pentapati AimsTo evaluate and compare the salivary content of malondialdehyde (MDA) in patients with type 2 diabetes and control subjects.MethodsWe conducted a cross-sectional study among 30 freshly diagnosed subjects of diabetes… Continue reading Role of salivary malondialdehyde in assessment of oxidative stress among diabetics
The risk for developing cancer in israeli ATM, BLM, and FANCC heterozygous mutation carriers
Publication date: Available online 22 December 2015 Source:Cancer Genetics Author(s): Yael Laitman, Lital Boker Keinan, Michal Berkenstadt, Irena Liphsitz, Daphna Weissglas-Volkov, Liat Ries-Levavi, Ifat Sarouk, Elon Pras, Eitan Friedman Cancer risks in heterozygous mutation carriers of the ATM, BLM and FANCC genes are controversial. To shed light on this issue, cancer rates were evaluated by… Continue reading The risk for developing cancer in israeli ATM, BLM, and FANCC heterozygous mutation carriers
Optimal strategy for obtaining routine chromosome analysis by using negative fractions of CD138 enriched plasma cells
Publication date: Available online 23 December 2015 Source:Cancer Genetics Author(s): Veronica Ortega, Gihan Mohamed, William Ehman, Meiqing Zhu, Christina Mendiola, Gopalrao Velagaleti Fluorescence in situ hybridization (FISH) is superior to routine chromosome analysis (RCA) in detecting important prognostic genetic abnormalities in plasma cell dyscrasia (PCD); however, its sensitivity is hampered due to paucity of plasma… Continue reading Optimal strategy for obtaining routine chromosome analysis by using negative fractions of CD138 enriched plasma cells
Circle of Willis of the brain: anatomical variations and their importance
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFLZUp via IFTTT
Cutaneous Histiocytoid Sweet Syndrome & its Relationship to Hematological Diseases
Abstract Sweet syndrome (SS) was described over 50 years ago as a distinctive form of neutrophilic dermatosis. It may be idiopathic, drug-induced, or paranaeoplastic, and, in the last of those subtypes, myeloproliferative diseases are prominently represented. A peculiar variant of SS is termed “histiocytoid” SS (HSS), and early accounts of that condition asserted that it… Continue reading Cutaneous Histiocytoid Sweet Syndrome & its Relationship to Hematological Diseases
A Randomized Trial of Motivational Interviewing
Publication date: Available online 23 December 2015 Source:American Journal of Preventive Medicine Author(s): Delwyn Catley, Kathy Goggin, Kari Jo Harris, Kimber P. Richter, Karen Williams, Christi Patten, Ken Resnicow, Edward F. Ellerbeck, Andrea Bradley-Ewing, Hyoung S. Lee, Jose L. Moreno, James E. Grobe IntroductionDespite limitations in evidence, the current Clinical Practice Guideline advocates Motivational Interviewing… Continue reading A Randomized Trial of Motivational Interviewing
Comparative histopathologic analysis of cutaneous extranodal natural killer/T-cell lymphomas according to their clinical morphology
Abstract Background Few studies have evaluated the histopathologic features of cutaneous extranodal NK/T-cell lymphoma, and the histopathologic spectrum of this disease according to its clinical morphology remains unclear. Objective This study investigated the differences in pathologic findings of cutaneous extranodal NK/T-cell lymphoma depending on clinical morphology. Methods A total of 41 cases of cutaneous extranodal… Continue reading Comparative histopathologic analysis of cutaneous extranodal natural killer/T-cell lymphomas according to their clinical morphology
Metastatic Renal Cell Carcinoma Presenting as Nasal Mass: Case Report and Review of Literature
Abstract Sinonasal neoplasms are rare and exceptional site for metastatic tumours and comprising <3 % of all malignant aerodigestive tumours and <1 % of all malignancies. Renal cell carcinoma is known to metastasise to the most unusual sites, the sinonasal region being one of them. We here by present a case of 60 year old… Continue reading Metastatic Renal Cell Carcinoma Presenting as Nasal Mass: Case Report and Review of Literature
Melatonin localization in human salivary glands
Background Circulating melatonin is believed to reach body fluids by crossing passively the cell membranes, but alternative ways for melatonin transport also are hypothesized. This investigation was carried out to furnish ultrastructural evidences for melatonin transport by salivary gland cells in order to indicate plausible routes by which circulating melatonin can reach saliva. Methods Bioptic… Continue reading Melatonin localization in human salivary glands
Treatment of chronic diabetic lower extremity ulcers with advanced therapies: a prospective, randomised, controlled, multi-centre comparative study examining clinical efficacy and cost
Abstract Advanced therapies such as bioengineered skin substitutes (BSS) and dehydrated human amnion/chorion membrane (dHACM) have been shown to promote healing of chronic diabetic ulcers. An interim analysis of data from 60 patients enrolled in a prospective, randomised, controlled, parallel group, multi-centre clinical trial showed that dHACM (EpiFix®, MiMedx Group Inc., Marietta, GA) is superior to standard wound care (SWC) and BSS (Apligraf®, Organogenesis, Inc., Canton, MA) in achieving complete wound closure within 4–6 weeks. Rates and time to closure at a longer time interva... περισσότερα »
Effect of three typical sulfide mineral flotation collectors on soil microbial activity
Abstract The sulfide mineral flotation collectors are wildly used in China, whereas their toxic effect on soil microbial activity remains largely unexplored. In this study, isothermal microcalorimetric technique and soil enzyme assay techniques were employed to investigate the toxic effect of typical sulfide mineral flotation collectors on soil microbial activity. Soil samples were treated with different concentrations (0–100 μg•g − 1 soil) of butyl xanthate, butyl dithiophosphate, and sodium diethyldithiocarbamate. Results showed a significant adverse effect of butyl xanthate (*p*... περισσότερα »
Spatio-temporal distribution of fecal indicators in three rivers of the Haihe River Basin, China
Abstract Because of their significant impact on public health, waterborne pathogens, especially bacteria and viruses, are frequently monitored in surface water to assess microbial quality of water bodies. However, more than one billion people worldwide currently lack access to safe drinking water, and a diversity of waterborne outbreaks caused by pathogens is reported in nations at all levels of economic development. Spatio-temporal distribution of conventional pollutants and five pathogenic microorganisms were discussed for the Haihe River Basin. Land use and socio-economic asses... περισσότερα »
Acute kidney injury
Clinical Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NLfYVc via IFTTT
Effect of hemodiafiltration therapy in a low-birthweight infant with congenital sepsis
Pediatrics International from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1On6PYg via IFTTT
The risk for developing cancer in israeli ATM, BLM, and FANCC heterozygous mutation carriers
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Publication date: Available online 22 December 2015 Source:Cancer Genetics Author(s): Yael Laitman, Lital Boker Keinan, Michal Berkenstadt, Irena Liphsitz, Daphna Weissglas-Volkov, Liat Ries-Levavi, Ifat Sarouk, Elon Pras, Eitan Friedman Cancer risks in heterozygous mutation carriers of the ATM, BLM and FANCC genes are controversial. To shed light on this issue, cancer rates were evaluated by […]
Optimal strategy for obtaining routine chromosome analysis by using negative fractions of CD138 enriched plasma cells
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Publication date: Available online 23 December 2015 Source:Cancer Genetics Author(s): Veronica Ortega, Gihan Mohamed, William Ehman, Meiqing Zhu, Christina Mendiola, Gopalrao Velagaleti Fluorescence in situ hybridization (FISH) is superior to routine chromosome analysis (RCA) in detecting important prognostic genetic abnormalities in plasma cell dyscrasia (PCD); however, its sensitivity is hampered due to paucity of plasma […]
Circle of Willis of the brain: anatomical variations and their importance
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
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Pancreatic head cancer involving variant common hepatic artery with situs inversus totalis
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Traumatic intrapericardial diaphragmatic hernia: findings on a computed tomography scan
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Welche Risikogruppen gibt es — wann und wie ist zu handeln?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Ernährungsdefizite in der Schwangerschaft Worauf es bei der ernährungsmedizinischen Betreuung schwangerer Frauen ankommt, vor allem bei Risikopatientinnen, erläutert Ernährungsmediziner Prof. Dr. Hans Hauner, München. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1U4amJs via IFTTT
Welche Risikogruppen gibt es — wann und wie ist zu handeln?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Ernährungsdefizite in der Schwangerschaft Worauf es bei der ernährungsmedizinischen Betreuung schwangerer Frauen ankommt, vor allem bei Risikopatientinnen, erläutert Ernährungsmediziner Prof. Dr. Hans Hauner, München. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1U4amJs via IFTTT
Adverse events in the treatment of MDR-TB patients within and outside the NTP in Pham Ngoc Thach hospital, Ho Chi Minh City, Vietnam
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Abstract Background Treatment outcomes of a high proportion of inpatients with multi-drug resistant tuberculosis (MDR-TB) were not reported to the Vietnamese National Tuberculosis Program because they received treatment outside of the green light committee (GLC) program. The study aimed (1) to describe the strengths and weaknesses of treatment of GLC and non-GLC MDR-TB patients as […]
Reproducibility of a novel computed-tomography based measurement of renal papillary density in the Framingham Heart Study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Abstract Background Renal papillary calcification is a compelling candidate risk factor for chronic kidney disease (CKD) and nephrolithiasis. Renal papillary density (RPD), as assessed by computed tomography (CT), is a potential marker for calcification that has not been well studied. We developed a protocol to measure RPD using CT scans and assessed its reproducibility in […]
The 5As team intervention: bridging the knowledge gap in obesity management among primary care practitioners
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Abstract Background Despite opportunities for didactic education on obesity management, we still observe low rates of weight management visits in our primary care setting. This paper describes the co-creation by front-line interdisciplinary health care providers and researchers of the 5As Team intervention to improve obesity prevention and management in primary care. Methods We describe the […]
A systematic review of the impact of center volume in dialysis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Abstract Background A significant relationship exists between the volume of surgical procedures that a given center performs and subsequent outcomes. It seems plausible that such a volume–outcome relationship is also present in dialysis. Methods MEDLINE and EMBASE were searched in November 2014 for non-experimental studies evaluating the association between center volume and patient outcomes [mortality, […]
Adverse events in the treatment of MDR-TB patients within and outside the NTP in Pham Ngoc Thach hospital, Ho Chi Minh City, Vietnam
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Abstract Background Treatment outcomes of a high proportion of inpatients with multi-drug resistant tuberculosis (MDR-TB) were not reported to the Vietnamese National Tuberculosis Program because they received treatment outside of the green light committee (GLC) program. The study aimed (1) to describe the strengths and weaknesses of treatment of GLC and non-GLC MDR-TB patients as […]
Reproducibility of a novel computed-tomography based measurement of renal papillary density in the Framingham Heart Study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Abstract Background Renal papillary calcification is a compelling candidate risk factor for chronic kidney disease (CKD) and nephrolithiasis. Renal papillary density (RPD), as assessed by computed tomography (CT), is a potential marker for calcification that has not been well studied. We developed a protocol to measure RPD using CT scans and assessed its reproducibility in […]
The 5As team intervention: bridging the knowledge gap in obesity management among primary care practitioners
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Abstract Background Despite opportunities for didactic education on obesity management, we still observe low rates of weight management visits in our primary care setting. This paper describes the co-creation by front-line interdisciplinary health care providers and researchers of the 5As Team intervention to improve obesity prevention and management in primary care. Methods We describe the […]
A systematic review of the impact of center volume in dialysis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Abstract Background A significant relationship exists between the volume of surgical procedures that a given center performs and subsequent outcomes. It seems plausible that such a volume–outcome relationship is also present in dialysis. Methods MEDLINE and EMBASE were searched in November 2014 for non-experimental studies evaluating the association between center volume and patient outcomes [mortality, […]
Tai Chi Exercise for Cancer-Related Fatigue in Patients with Lung Cancer Undergoing Chemotherapy: A Randomized Controlled Trial
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 51 δευτερόλεπτα
Context. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1V6xt76 via IFTTT
Pc-facs
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 51 δευτερόλεπτα
PC-FACS (Fast Article Critical Summaries for Clinicians in Palliative Care) provides hospice and palliative care clinicians with concise summaries of the most important findings from more than 100 medical and scientific journals. If you have colleagues who would benefit from receiving PC-FACS, please encourage them to join the AAHPM at aahpm.org. Comments from readers are […]
Demoralization Scale in Spanish-Speaking Palliative Care Patients
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 51 δευτερόλεπτα
Among the approaches to the demoralization syndrome, the one proposed by Kissane et al. is prevalent in the literature. These authors developed the Demoralization Scale (DS) in order to assess emotional distress, conceived as demoralization. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFIZHR via IFTTT from #Med Blogs by […]
Tai Chi Exercise for Cancer-Related Fatigue in Patients with Lung Cancer Undergoing Chemotherapy: A Randomized Controlled Trial
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 51 δευτερόλεπτα
Context. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1V6xt76 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1On4Fbd via IFTTT
Demoralization Scale in Spanish-Speaking Palliative Care Patients
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 51 δευτερόλεπτα
Among the approaches to the demoralization syndrome, the one proposed by Kissane et al. is prevalent in the literature. These authors developed the Demoralization Scale (DS) in order to assess emotional distress, conceived as demoralization. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RFIZHR via IFTTT from #Med Blogs by […]
Tai Chi Exercise for Cancer-Related Fatigue in Patients with Lung Cancer Undergoing Chemotherapy: A Randomized Controlled Trial
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 51 δευτερόλεπτα
Context. (Source: Journal of Pain and Symptom Management) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1V6xt76 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1On4Fb9 via IFTTT
India ready for robotic surgeries to treat head, neck cancer: Top US surgeon … – Business Standard (press release) (registration) (blog)
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 51 δευτερόλεπτα
India ready for robotic surgeries to treat head, neck cancer: Top US surgeon … Business Standard (press release) (registration) (blog) India has significant talent and expertise in traditional head and neck surgical procedures and the country is poised to take a giant leap with robot-assisted surgeries for head and neck patients in the days to […]
Nasopharyngeal Stenosis: A Rare Radiotherapy Complication
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 51 δευτερόλεπτα
Abstract Introduction Acquired nasopharyngeal stenosis after radiotherapy for NPC is rare. We report a case of bilateral choanal stenosis and nasopharygeal stenosis in patient treated with chemo radiotherapy for undifferentieted nasopharnygeal carcinoma. Case Report A 68 years old man treated for undifferentiated nasopharyngeal carcinoma with chemo-radiotherapy 10 years before. He complained of complete nasal obstruction, […]
Metastatic Renal Cell Carcinoma Presenting as Nasal Mass: Case Report and Review of Literature
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 51 δευτερόλεπτα
Abstract Sinonasal neoplasms are rare and exceptional site for metastatic tumours and comprising <3 % of all malignant aerodigestive tumours and <1 % of all malignancies. Renal cell carcinoma is known to metastasise to the most unusual sites, the sinonasal region being one of them. We here by present a case of 60 year old […]
Insulin knockout mice have extended survival but volatile blood glucose levels on leptin therapy
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1TgMIsZ via IFTTT
Dynamin is required for GnRH signaling to L-type calcium channels and activation of ERK
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Alpha-cell dysfunctions and molecular alterations in male insulinopenic diabetic mice are not completely corrected by insulin
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Expansion of bone marrow adipose tissue during caloric restriction is associated with increased circulating glucocorticoids and not with hypoleptinemia.
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Issue Information - TOC
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Issue Information - Journal Information
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The diagnostic utility of 3D electroencephalography source imaging in pediatric epilepsy surgery
Summary Objective The aim of this study was to investigate the utility of three-dimensional electroencephalography source imaging (3D-ESI) with low-resolution electroencephalographic data in the pediatric noninvasive presurgical evaluation, and to compare the findings with positron emission tomography (PET) and ictal single-photon emission computed tomography (iSPECT). Methods We retrospectively selected 60 patients from a database of 594 patients who underwent excisional surgery for drug-resistant epilepsy. Patients were <18 years at time of surgery, had at least one presurgical...περισσότερα »
The Anterior Subcallosal Approach to Third Ventricular and Suprasellar Lesions: Anatomical Description and Technical Note
Publication date: Available online 22 December 2015 *Source:*World Neurosurgery Author(s): Brandon D. Liebelt, Kristopher G. Hooten, Gavin W. Britz BackgroundSurgical access to the third ventricle is challenging given the depth of the operative field and close proximity of vital neural structures that must be traversed. For anterior third ventricular lesions approach options include anterior transcallosal or transcortical, subfrontal, frontotemporal, or endonasal.The subcallosal approach, a trans-lamina terminalis approach, is unique in that the surgical corridor is just below the c... περισσότερα »
Prevalence and Risk Factors Associated with Use of QT-Prolonging Drugs in Hospitalized Older People
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Aims The objective of this study was to evaluate the prevalence of the prescription of QT-prolonging drugs at hospital admission and discharge and the risk factors associated with their use in older people (aged 65 years and older). Methods Data were obtained from the REPOSI (REgistro POliterapie SIMI [Società Italiana di Medicina Interna]) registry, […]
Utilization of Portable Radios to Improve Ophthalmology Clinic Efficiency in an Academic Setting
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Improvement in clinic efficiency in the ambulatory setting is often looked at as an area for development of lean management strategies to deliver a higher quality of healthcare while reducing errors, costs, and delays. To examine the benefits of improving team communication and its impact on clinic flow and efficiency, we describe a time-motion […]
VehiHealth: An Emergency Routing Protocol for Vehicular Ad Hoc Network to Support Healthcare System
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Survival of a patient depends on effective data communication in healthcare system. In this paper, an emergency routing protocol for Vehicular Ad hoc Network (VANET) is proposed to quickly forward the current patient status information from the ambulance to the hospital to provide pre-medical treatment. As the ambulance takes time to reach the hospital, […]
Erythematöse Papeln an Abdomen, Flanke, Leiste und Penis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Wie lautet Ihre Diagnose? Ein 26-Jähriger stellt sich wegen seit dem 10. Lebensjahr bestehender kleinfleckiger Hautveränderungen in der Klinik vor. Er habe mehrmals täglich breiige Stühle und leide 1- bis 2-mal im Monat unter heftigen Bauchschmerzen. Die allergologische Anamnese ist unauffällig. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1On1tMF via IFTTT
Unklare Raumforderung im linken Oberbauch
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Eine chirurgische Rarität Die Vorstellung einer 50-jährigen Patientin erfolgte primär über die Notaufnahme mit Luftnot unter dem Verdacht einer Lungenembolie. Anamnestisch berichtete die Patientin über eine Behandlung aufgrund eines kutanen B-Zell-Lymphoms 6 Jahre zuvor. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1IpvtFm via IFTTT
Prevalence and Risk Factors Associated with Use of QT-Prolonging Drugs in Hospitalized Older People
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Aims The objective of this study was to evaluate the prevalence of the prescription of QT-prolonging drugs at hospital admission and discharge and the risk factors associated with their use in older people (aged 65 years and older). Methods Data were obtained from the REPOSI (REgistro POliterapie SIMI [Società Italiana di Medicina Interna]) registry, […]
Melatonin localization in human salivary glands
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background Circulating melatonin is believed to reach body fluids by crossing passively the cell membranes, but alternative ways for melatonin transport also are hypothesized. This investigation was carried out to furnish ultrastructural evidences for melatonin transport by salivary gland cells in order to indicate plausible routes by which circulating melatonin can reach saliva. Methods Bioptic […]
Utilization of Portable Radios to Improve Ophthalmology Clinic Efficiency in an Academic Setting
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Improvement in clinic efficiency in the ambulatory setting is often looked at as an area for development of lean management strategies to deliver a higher quality of healthcare while reducing errors, costs, and delays. To examine the benefits of improving team communication and its impact on clinic flow and efficiency, we describe a time-motion […]
Goitre among 6–12-year-old Children
Prevalence and Factors Associated with Goitre among 6–12-year-old Children in a Rural Area of Karnataka in South India: AbstractIn India, endemic goitre is present in sub-Himalayan region and in pockets in states of Andhra Pradesh, Karnataka and Gujarat. Being a public health problem amenable for prevention, the assessment of prevalence of endemic goitre in an area helps in understanding whether the preventive strategies under National Iodine Deficiency Disorder Control Program (NIDDCP) have any impact on the control of endemic goitre. Hence, the current study was carried out to de... περισσότερα »
Cisternography for the Detection of Cerebrospinal Fluid Leakage
Visual and Quantitative Analysis of Cisternography for the Detection of Cerebrospinal Fluid Leakage: AbstractWe herein present a case of a 29-year-old man with clear rhinorrhea, which persisted for 8 years following a myringotomy. After cotton pledgets were placed in several different regions of the nasal cavity, cisternography using Tc-99m DTPA was performed to measure the radioactivity of each pledget. Cisternography showed subtle uptake in the nasal cavity. However, intense uptake was detected in the pledget placed in the right eustachian tube orifice, where the pledget:serum co... περισσότερα »
Cutaneous Histiocytoid Sweet Syndrome & its Relationship to Hematological Diseases
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Sweet syndrome (SS) was described over 50 years ago as a distinctive form of neutrophilic dermatosis. It may be idiopathic, drug-induced, or paranaeoplastic, and, in the last of those subtypes, myeloproliferative diseases are prominently represented. A peculiar variant of SS is termed “histiocytoid” SS (HSS), and early accounts of that condition asserted that it […]
Comparative histopathologic analysis of cutaneous extranodal natural killer/T-cell lymphomas according to their clinical morphology
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Background Few studies have evaluated the histopathologic features of cutaneous extranodal NK/T-cell lymphoma, and the histopathologic spectrum of this disease according to its clinical morphology remains unclear. Objective This study investigated the differences in pathologic findings of cutaneous extranodal NK/T-cell lymphoma depending on clinical morphology. Methods A total of 41 cases of cutaneous extranodal […]
A Randomized Trial of Motivational Interviewing
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 23 December 2015 Source:American Journal of Preventive Medicine Author(s): Delwyn Catley, Kathy Goggin, Kari Jo Harris, Kimber P. Richter, Karen Williams, Christi Patten, Ken Resnicow, Edward F. Ellerbeck, Andrea Bradley-Ewing, Hyoung S. Lee, Jose L. Moreno, James E. Grobe IntroductionDespite limitations in evidence, the current Clinical Practice Guideline advocates Motivational Interviewing […]
Melatonin localization in human salivary glands
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Background Circulating melatonin is believed to reach body fluids by crossing passively the cell membranes, but alternative ways for melatonin transport also are hypothesized. This investigation was carried out to furnish ultrastructural evidences for melatonin transport by salivary gland cells in order to indicate plausible routes by which circulating melatonin can reach saliva. Methods Bioptic […]
Metastatic Renal Cell Carcinoma Presenting as Nasal Mass: Case Report and Review of Literature
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Sinonasal neoplasms are rare and exceptional site for metastatic tumours and comprising <3 % of all malignant aerodigestive tumours and <1 % of all malignancies. Renal cell carcinoma is known to metastasise to the most unusual sites, the sinonasal region being one of them. We here by present a case of 60 year old […]
VehiHealth: An Emergency Routing Protocol for Vehicular Ad Hoc Network to Support Healthcare System
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Survival of a patient depends on effective data communication in healthcare system. In this paper, an emergency routing protocol for Vehicular Ad hoc Network (VANET) is proposed to quickly forward the current patient status information from the ambulance to the hospital to provide pre-medical treatment. As the ambulance takes time to reach the hospital, […]
Unklare Raumforderung im linken Oberbauch
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Eine chirurgische Rarität Die Vorstellung einer 50-jährigen Patientin erfolgte primär über die Notaufnahme mit Luftnot unter dem Verdacht einer Lungenembolie. Anamnestisch berichtete die Patientin über eine Behandlung aufgrund eines kutanen B-Zell-Lymphoms 6 Jahre zuvor. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1IpvtFm via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OKsN1R […]
Erythematöse Papeln an Abdomen, Flanke, Leiste und Penis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Wie lautet Ihre Diagnose? Ein 26-Jähriger stellt sich wegen seit dem 10. Lebensjahr bestehender kleinfleckiger Hautveränderungen in der Klinik vor. Er habe mehrmals täglich breiige Stühle und leide 1- bis 2-mal im Monat unter heftigen Bauchschmerzen. Die allergologische Anamnese ist unauffällig. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1On1tMF via IFTTT from #Med Blogs by Alexandros […]
Nasopharyngeal Stenosis: A Rare Radiotherapy Complication
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Introduction Acquired nasopharyngeal stenosis after radiotherapy for NPC is rare. We report a case of bilateral choanal stenosis and nasopharygeal stenosis in patient treated with chemo radiotherapy for undifferentieted nasopharnygeal carcinoma. Case Report A 68 years old man treated for undifferentiated nasopharyngeal carcinoma with chemo-radiotherapy 10 years before. He complained of complete nasal obstruction, […]
Role of distinct CD4+ T helper subset in pathogenesis of oral lichen planus
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Oral lichen planus (OLP) is one of the most common chronic inflammatory oral mucosal diseases with T-cell-mediated immune pathogenesis. In subepithelial and lamina propria of OLP local lesions, the presence of CD4+ T helper (CD4+ Th) cells appeared as the major lymphocytes. These CD4+ T lymphocytes can differentiate into distinct Th cell types such as […]
Single plasmonic nanoparticles for ultrasensitive DNA sensing: From invisible to visible
[image: S09565663.gif] Publication date: 15 May 2016 *Source:*Biosensors and Bioelectronics, Volume 79 Author(s): Longhua Guo, Lichan Chen, Seungpyo Hong, Dong-Hwan Kim The background signal is a major factor that restricts the limit of detection of biosensors. Herein, we present a zero-background DNA-sensing approach that utilizes enzyme-guided gold nanoparticle (AuNP) enlargement. This sensing strategy is based on the finding that small nanoparticles are invisible under a darkfield optical microscope, thus completely eliminating the background signal. In the event of target binding...περισσότερα »
Functionalized gold nanoparticles/reduced graphene oxide nanocomposites for ultrasensitive electrochemical sensing of mercury ions based on thymine–mercury–thymine structure
[image: S09565663.gif] Publication date: 15 May 2016 *Source:*Biosensors and Bioelectronics, Volume 79 Author(s): Nan Wang, Meng Lin, Hongxiu Dai, Houyi Ma A sensitive, selective and reusable electrochemical biosensor for the determination of mercury ions (Hg2+) has been developed based on thymine (T) modified gold nanoparticles/reduced graphene oxide (AuNPs/rGO) nanocomposites. Graphene oxide (GO) was electrochemically reduced on a glassy carbon substrate. Subsequently, AuNPs were deposited onto the surface of rGO by cyclic voltammetry. For functionalization of the electrode, the c... περισσότερα »
Two-stage cyclic enzymatic amplification method for ultrasensitive electrochemical assay of microRNA-21 in the blood serum of gastric cancer patients
Publication date: 15 May 2016 *Source:*Biosensors and Bioelectronics, Volume 79 Author(s): Bingchen Li, Fei Liu, Yuanyuan Peng, Yunlei Zhou, Wenxuan Fan, Huanshun Yin, Shiyun Ai, Xiansheng Zhang MicroRNA (miRNA) is riveting nowadays due to its close relevance to human malignancies. Exploiting a fast and convenient biosensor for sensitive and specific detecting miRNA is necessary and it has significant meaning for oncology. In this work, to understand the relationship between miRNA-21 and gastric cancer, we employ T4 RNA ligase 2 to initiate specific ligation reaction depending on th... περισσότερα »
VehiHealth: An Emergency Routing Protocol for Vehicular Ad Hoc Network to Support Healthcare System
Abstract Survival of a patient depends on effective data communication in healthcare system. In this paper, an emergency routing protocol for Vehicular Ad hoc Network (VANET) is proposed to quickly forward the current patient status information from the ambulance to the hospital to provide pre-medical treatment. As the ambulance takes time to reach the hospital,… Continue reading VehiHealth: An Emergency Routing Protocol for Vehicular Ad Hoc Network to Support Healthcare System
Metastatic Renal Cell Carcinoma Presenting as Nasal Mass: Case Report and Review of Literature
Abstract Sinonasal neoplasms are rare and exceptional site for metastatic tumours and comprising <3 % of all malignant aerodigestive tumours and <1 % of all malignancies. Renal cell carcinoma is known to metastasise to the most unusual sites, the sinonasal region being one of them. We here by present a case of 60 year old… Continue reading Metastatic Renal Cell Carcinoma Presenting as Nasal Mass: Case Report and Review of Literature
Erythematöse Papeln an Abdomen, Flanke, Leiste und Penis
Wie lautet Ihre Diagnose? Ein 26-Jähriger stellt sich wegen seit dem 10. Lebensjahr bestehender kleinfleckiger Hautveränderungen in der Klinik vor. Er habe mehrmals täglich breiige Stühle und leide 1- bis 2-mal im Monat unter heftigen Bauchschmerzen. Die allergologische Anamnese ist unauffällig. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1On1tMF via IFTTT
Nasopharyngeal Stenosis: A Rare Radiotherapy Complication
Abstract Introduction Acquired nasopharyngeal stenosis after radiotherapy for NPC is rare. We report a case of bilateral choanal stenosis and nasopharygeal stenosis in patient treated with chemo radiotherapy for undifferentieted nasopharnygeal carcinoma. Case Report A 68 years old man treated for undifferentiated nasopharyngeal carcinoma with chemo-radiotherapy 10 years before. He complained of complete nasal obstruction,… Continue reading Nasopharyngeal Stenosis: A Rare Radiotherapy Complication
Melatonin localization in human salivary glands
Background Circulating melatonin is believed to reach body fluids by crossing passively the cell membranes, but alternative ways for melatonin transport also are hypothesized. This investigation was carried out to furnish ultrastructural evidences for melatonin transport by salivary gland cells in order to indicate plausible routes by which circulating melatonin can reach saliva. Methods Bioptic… Continue reading Melatonin localization in human salivary glands
Unklare Raumforderung im linken Oberbauch
Eine chirurgische Rarität Die Vorstellung einer 50-jährigen Patientin erfolgte primär über die Notaufnahme mit Luftnot unter dem Verdacht einer Lungenembolie. Anamnestisch berichtete die Patientin über eine Behandlung aufgrund eines kutanen B-Zell-Lymphoms 6 Jahre zuvor. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1IpvtFm via IFTTT
Role of distinct CD4+ T helper subset in pathogenesis of oral lichen planus
Oral lichen planus (OLP) is one of the most common chronic inflammatory oral mucosal diseases with T-cell-mediated immune pathogenesis. In subepithelial and lamina propria of OLP local lesions, the presence of CD4+ T helper (CD4+ Th) cells appeared as the major lymphocytes. These CD4+ T lymphocytes can differentiate into distinct Th cell types such as… Continue reading Role of distinct CD4+ T helper subset in pathogenesis of oral lichen planus
Melatonin localization in human salivary glands
Background Circulating melatonin is believed to reach body fluids by crossing passively the cell membranes, but alternative ways for melatonin transport also are hypothesized. This investigation was carried out to furnish ultrastructural evidences for melatonin transport by salivary gland cells in order to indicate plausible routes by which circulating melatonin can reach saliva. Methods Bioptic… Continue reading Melatonin localization in human salivary glands
Immunohistochemical expression of matrix metalloproteinases in ameloblastomas and pericoronal follicles
Background Ameloblastoma (AM) is a benign odontogenic neoplasm characterized by local invasiveness and recurrence. We compared the immunohistochemical expression of matrix metalloproteinases in different clinical types of AM as well as in normal odontogenic tissue. Methods Thirteen cases of solid AMs, five cases of unicystic AM and eight pericoronal follicles (PF) were selected and subjected… Continue reading Immunohistochemical expression of matrix metalloproteinases in ameloblastomas and pericoronal follicles
Immunohistochemical expression of matrix metalloproteinases in ameloblastomas and pericoronal follicles
Background Ameloblastoma (AM) is a benign odontogenic neoplasm characterized by local invasiveness and recurrence. We compared the immunohistochemical expression of matrix metalloproteinases in different clinical types of AM as well as in normal odontogenic tissue. Methods Thirteen cases of solid AMs, five cases of unicystic AM and eight pericoronal follicles (PF) were selected and subjected… Continue reading Immunohistochemical expression of matrix metalloproteinases in ameloblastomas and pericoronal follicles
Human papillomavirus-related lesions in patients with organ transplantation
Clinical outcomes of abnormal cervical cytology and human papillomavirus-related lesions in patients with organ transplantation: 11-year experience at a single institution: Abstract ObjectivesThe objective of this study is to analyze the clinical outcomes of abnormal cervical cytology and newly diagnosed human papillomavirus (HPV)-related disease after organ transplantation. Materials and methodsMedical records from July 2004 to August 2015 were reviewed, and thirteen patients were identified who had been newly diagnosed with HPV-related disease (cervical intraepithelial neopla...περισσότερα »
The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphane
The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphane: Melanoma is a metastatic cancer associated with poor survival. Here, we study a subpopulation of melanoma cancer cells displaying melanoma cancer stem cell (MCS cells) properties including elevated expression of stem cell markers, increased ability to survive as spheroids, and enhanced cell migration and invasion. We show that the Ezh2 stem cell survival protein is enriched in MCS cells and that Ezh2 knockdown or treatment with small molecule Ez...περισσότερα »
Anti-Hu Antibody Associated Paraneoplastic Cerebellar Degeneration in Head and Neck Cancer
Anti-Hu Antibody Associated Paraneoplastic Cerebellar Degeneration in Head and Neck Cancer: Abstract BackgroundParaneoplastic syndromes are most frequently associated with small cell lung carcinoma, hematologic and gynecologic malignancies while reports in head and neck cancer are rare. Case presentationWe present the case of a 60-year old female patient who developed paraneoplastic cerebellar degeneration upon locoregional recurrence of a poorly differentiated spindle cell carcinoma of the nasal cavity and paranasal sinus. The neurological symptoms, especially ataxia, stabili... περισσότερα »
The effect of morphometric atlas selection on multi-atlas-based automatic brachial plexus segmentation
The effect of morphometric atlas selection on multi-atlas-based automatic brachial plexus segmentation: The present study aimed to measure the effect of a morphometric atlas selection strategy on the accuracy of multi-atlas-based BP autosegmentation using the commercially available software package ADMIRE® and t... Abstract Purpose The present study aimed to measure the effect of a morphometric atlas selection strategy on the accuracy of multi-atlas-based BP autosegmentation using the commercially available software package ADMIRE® and to determine the optimal number of selec... περισσότερα »
Salivary-free fluoride ion concentration
Salivary-free fluoride ion concentration measured using a flow-injection analysis device and oral environment in 4–6-year-old children: AbstractAlthough fluoride (F) products are widely used for caries prevention, the safest and most effective modes of application, in particular for young children, remain to be elucidated. The limitations associated with the detection of ultra-low F ion concentrations are the major obstacles in accurately assessing the salivary F ion concentrations in children. This study aimed to measure accurate salivary-free F ion concentrations in children usin... περισσότερα »
Dexmedetomidine (12.5 μg/mL) improves tissue distribution, anesthetic action, and hemodynamic effects of lidocaine after palatal infiltration in rats
Dexmedetomidine (12.5 μg/mL) improves tissue distribution, anesthetic action, and hemodynamic effects of lidocaine after palatal infiltration in rats: AbstractDexmedetomidine hydrochloride (DEX) is a α2-adrenergic receptor agonist that causes vasoconstriction by acting on α2B-adrenergic receptors in peripheral blood vessels. The authors aimed to determine the influence of DEX on tissue distribution, anesthetic action, and hemodynamic effects of lidocaine in rats. The investigators injected indigo carmine-containing 14C-labeled lidocaine hydrochloride (2 %) without and with 3.1, 12.... περισσότερα »
Reflex ankle stiffness is inversely correlated with natural body sway
Reflex ankle stiffness is inversely correlated with natural body sway via Gait & Posture Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Brianna L. Julien, Andrew P. Bendrups We aimed to determine whether effective ankle stiffness (EAS), measured during slow unperceived perturbations of stance, is related to natural anterior–posterior body sway. Because the perturbations are not perceived, any neural component of the response to perturbation is assumed to be “reflex”, in the broad sense of an involuntary response to a stimulus. Subjects stood on a force pl...περισσότερα »
Recurrent nonspecific low back pain: Balance recovery reactions
Balance recovery reactions in individuals with recurrent nonspecific low back pain: Effect of attention via Gait & Posture Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Yasaman Etemadi, Mahyar Salavati, Amir M. Arab, Tabassom Ghanavati People who suffer from Low Back Pain (LBP) demonstrate impaired postural control. Deficits in sensory-motor systems have been proposed to be related to these changes. Considering higher cognitive process contribution to postural control, the aim of this study was to investigate the effects of cognitive load on balance con...περισσότερα »
Gait & Posture
The use of force-plate posturography in the assessment of postural instability Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Janusz W. Błaszczyk Force-plate posturography is a simple method that is commonly used in the contemporary laboratory and clinic to assess postural control. Despite the obvious advantages and popularity of the method, universal standards for posturographic tests have not been developed thus far: most postural assessments are based on the standard spatiotemporal metrics of the center-of-foot pressure (COP) recorded during qui...περισσότερα »
Age-related changes in postural sway in preschoolers
Age-related changes in postural sway in preschoolers via Gait & Posture Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Evi Verbecque, Paula Hentschel Lobo da Costa, Pieter Meyns, Kaat Desloovere, Luc Vereeck, Ann Hallemans ObjectivesThe present study aimed to investigate age-related differences of postural sway in 3- to 6-year-old typically developing children in different sensory conditions and subsequently to provide reference values for global descriptive sway parameters in preschoolers.MethodsNinety-six typically developing children, between 3 and 5 y... περισσότερα »
Empirical prediction of peak pressure levels in anthropogenic impulsive noise. Part I: Airgun arrays signals
Empirical prediction of peak pressure levels in anthropogenic impulsive noise. Part I: Airgun arrays signals: This paper presents an empirical linear equation to predict peak pressure level of anthropogenic impulsive signals based on its correlation with the sound exposure level. The regression coefficients are shown to be weakly dependent on the environmental characteristics but governed by the source type and parameters. The equation can be applied to values of the sound exposure level predicted with a numerical model, which provides a significant improvement in the prediction of...περισσότερα »
Precedence based speech segregation in bilateral cochlear implant users
Precedence based speech segregation in bilateral cochlear implant users: The precedence effect (PE) enables the perceptual dominance by a source (lead) over an echo (lag) in reverberant environments. In addition to facilitating sound localization, the PE can play an important role in spatial unmasking of speech. Listeners attending to binaural vocoder simulations with identical channel center frequencies and phase demonstrated PE-based benefits in a closed-set speech segregation task. When presented with the same stimuli, bilateral cochlear implant users did not derive such benefit...περισσότερα »
Lexical and age effects on word recognition in noise
in normal-hearing children via International Journal of Pediatric Otorhinolaryngology Publication date: December 2015 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 79, Issue 12 Author(s): Cuncun Ren, Sha Liu, Haihong Liu, Ying Kong, Xin Liu, Shujing Li ObjectivesThe purposes of the present study were (1) to examine the lexical and age effects on word recognition of normal-hearing (NH) children in noise, and (2) to compare the word-recognition performance in noise to that in quiet listening conditions.MethodsParticipants were 213 NH children (age ranged betwee...περισσότερα »
Auditory neuropathy spectrum disorder (ANSD) and cochlear implantation
Auditory neuropathy spectrum disorder (ANSD) and cochlear implantation via International Journal of Pediatric Otorhinolaryngology Publication date: December 2015 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 79, Issue 12 Author(s): Robert V. Harrison, Karen A. Gordon, Blake C. Papsin, Jaina Negandhi, Adrian L. James We discuss issues related to cochlear implantation in children with auditory neuropathy spectrum disorder (ANSD). We describe the varied nature of this disease category including the numerous potential causes of auditory neuropathy. The most preval... περισσότερα »
House Brackmann grade 2 marginal mandibular nerve palsy : Parotid abscess in children
– A tertiary rural hospital experience via International Journal of Pediatric Otorhinolaryngology Publication date: December 2015 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 79, Issue 12 Author(s): M. Lakshmi Narayana, S.M. Azeem Mohiyuddin, Kouser Mohammadi, Anushka V. Devnikar, K.N.V. Prasad Parotid abscess is a rare complication of acute parotitis in children. Acute parotitis occurs due to infection of intra-parotid or para-parotid lymph nodes or glandular parenchyma of the parotid gland which may progress to parotid abscess.ObjectivesTo document the cau... περισσότερα »
Prevalence and Predictors of Thyroid Dysfunction in Patients with HIV Infection and Acquired Immunodeficiency Syndrome: An Indian Perspective
Prevalence and Predictors of Thyroid Dysfunction in Patients with HIV Infection and Acquired Immunodeficiency Syndrome: An Indian Perspective: Background. Predictors of thyroid dysfunction in HIV are not well determined. This study aimed to determine the prevalence and predictors of thyroid dysfunction in HIV infected Indians. Methods. Consecutive HIV patients, 18–70 years of age, without any severe comorbid state, having at least 1-year follow-up at the antiretroviral therapy clinic, underwent clinical assessment and hormone assays. Results. From initially screened 527 patients, 35... περισσότερα »
Initial Management in Patients With Differentiated Thyroid Cancer
Initial Management in Patients With Differentiated Thyroid Cancer in the Real World in China: *Condition*: Differentiated Thyroid Cancer *Intervention*: *Sponsors*: Huazhong University of Science and Technology; West China Hospital; The First Affiliated Hospital of Kunming Medical College; Sir Run Run Shaw Hospital; Jilin University; Chinese PLA General Hospital; Gansu Cancer Hospital; Tongji Hospital; First Hospital of China Medical University Primary Outcome Measures: - Proportion of patients who underwent total/near-total thyroidectomy [ Time F... περισσότερα »
The XPD and XRCC3 gene Polymorphisms with Oral Squamous Cell Carcinoma
Association of the XPD and XRCC3 gene Polymorphisms with Oral Squamous Cell Carcinoma in a Northeastern Brazilian Population: A Pilot Study via Oral Biology Publication date: Available online 22 December 2015 *Source:*Archives of Oral Biology Author(s): Joabe dos Santos Pereira, Fabrícia Lima Fontes, Silvia Regina Batistuzzo de Medeiros, Roseana de Almeida Freitas, Lélia Batista de Souza, Márcia Cristina da Costa Miguel Objectiveto evaluate the association between XPD and XRCC3 polymorphisms and oral squamous cell carcinoma (OSCC).Designthe sample consisted of 54 cases of OSCC and 40 c... περισσότερα »
Nasopharyngeal Stenosis: A Rare Radiotherapy Complication
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Abstract Introduction Acquired nasopharyngeal stenosis after radiotherapy for NPC is rare. We report a case of bilateral choanal stenosis and nasopharygeal stenosis in patient treated with chemo radiotherapy for undifferentieted nasopharnygeal carcinoma. Case Report A 68 years old man treated for undifferentiated nasopharyngeal carcinoma with chemo-radiotherapy 10 years before. He complained of complete nasal obstruction, […]
Reduced Follow-Up May Be Reasonable for HPV+ Oropharyngeal SCC – Oncology Nurse Advisor
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Oncology Nurse Advisor Reduced Follow-Up May Be Reasonable for HPV+ Oropharyngeal SCC Oncology Nurse Advisor … first 6 months of follow-up, according to a new study published online ahead of print in the journal Cancer. Because optimal follow-up can help maximize utilization of health care resources, particularly for the growing number of patients with HPV+ […]
IJERPH, Vol. 13, Pages 22: Hot Spot Mutation in TP53 (R248Q) Causes Oncogenic Gain-of-Function Phenotypes in a Breast Cancer Cell Line Derived from an African American patient
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
African American (AA) breast cancer patients often have triple negative breast cancer (TNBC) that contains mutations in the TP53 gene. The point mutations at amino acid residues R273 and R248 both result in oncogenic gain-of-function (GOF) phenotypes. Expression of mutant p53 (mtp53) R273H associates with increased cell elasticity, survival under serum deprivation conditions, and increased […]
Melatonin localization in human salivary glands
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Background Circulating melatonin is believed to reach body fluids by crossing passively the cell membranes, but alternative ways for melatonin transport also are hypothesized. This investigation was carried out to furnish ultrastructural evidences for melatonin transport by salivary gland cells in order to indicate plausible routes by which circulating melatonin can reach saliva. Methods Bioptic […]
Immunohistochemical expression of matrix metalloproteinases in ameloblastomas and pericoronal follicles
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Background Ameloblastoma (AM) is a benign odontogenic neoplasm characterized by local invasiveness and recurrence. We compared the immunohistochemical expression of matrix metalloproteinases in different clinical types of AM as well as in normal odontogenic tissue. Methods Thirteen cases of solid AMs, five cases of unicystic AM and eight pericoronal follicles (PF) were selected and subjected […]
Role of distinct CD4+ T helper subset in pathogenesis of oral lichen planus
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Oral lichen planus (OLP) is one of the most common chronic inflammatory oral mucosal diseases with T-cell-mediated immune pathogenesis. In subepithelial and lamina propria of OLP local lesions, the presence of CD4+ T helper (CD4+ Th) cells appeared as the major lymphocytes. These CD4+ T lymphocytes can differentiate into distinct Th cell types such as […]
Sleep, mental status, and biological markers in saliva in patients with oral lichen planus
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1V69SDH via IFTTT
Effect of a 2% topical chamomile application for treating burning mouth syndrome: a controlled clinical trial
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Background The treatments for burning mouth syndrome (BMS) proposed to date have been varied but have only achieved limited efficacy. Chamomile has analgesic and anti-inflammatory properties. The aim of this study was to evaluate the efficacy of topical applications of 2% chamomile gel in comparison with a placebo for the treatment of BMS. Materials and […]
PLGA nanoparticle delivery System for 5-fluorouracil and curcumin on squamous cell carcinoma
Comparative evaluation of via Oral Biology Publication date: Available online 21 December 2015 *Source:*Archives of Oral Biology Author(s): Shaimaa M. Masloub, Mohamed H. Elmalahy, Dina Sabry, Wael S. Mohamed, Sahar H. Ahmed PurposeThe purpose of this study is to assess the effect of 5-fluorouracil nanoparticles and curcumin naoparticles on cell proliferation and the expression of the apoptotic marker (caspase 3) in squamous cell carcinoma cell line.Material and methodsPLGA 5-fluorouracil nanopartciles and PLGA curcumin nanoparticles were prepared and applied for 24 and 48hours on hu... περισσότερα »
Duchenne smile
Kinematic analysis of a Duchenne smile via Oral Biology Publication date: Available online 22 December 2015 *Source:*Archives of Oral Biology Author(s): H. Jaffer, E. Ichesco, G.E. Gerstner ObjectiveFacial expressions are communicative motor outputs, whose kinematics likely are due to musculoskeletal anatomy, neuromotor activity and the well-being and internal states of the individual. However, little has been published on the kinematics of facial expression. This study quantified lip, eye and cheek movements during the production of a Duchenne smile involving movement of lips and tiss... περισσότερα »
Neuroendoscopy for Intraventricular Tumor Resection
Publication date: Available online 22 December 2015 *Source:*World Neurosurgery Author(s): Brandon Rocque from Neurology via xlomafota13 on Inoreader http://ift.tt/22psEdW via IFTTT
Analysis of factors contributing to infections following cranioplasty: a single-institution retrospective chart review
Publication date: Available online 22 December 2015 *Source:*World Neurosurgery Author(s): Margaret A. Riordan, Venita M. Simpson, Walter A. Hall from Neurology via xlomafota13 on Inoreader http://ift.tt/1TgMKBb via IFTTT
Peroneal intraneural ganglia formation causing foot drop in children; clinical perspective
Publication date: Available online 22 December 2015 *Source:*World Neurosurgery Author(s): Line Jacques from Neurology via xlomafota13 on Inoreader http://ift.tt/22psDXI via IFTTT
Predictors of Outcome in Traumatic Brain Injury
Publication date: Available online 22 December 2015 *Source:*World Neurosurgery Author(s): Justin Baum, Pouya Entezami, Kavit Shah, Azedine Medhkour IntroductionThe purpose of this study was to retrospectively evaluate patients treated for traumatic brain injuries (TBI) to determine how multiple organ trauma (MOT) and lung injuries sustained at the time of initial injury affect outcome.MethodA single institution retrospective review of all patients diagnosed with TBI at a level I trauma center from 2000-2014 was conducted. Clinical outcome was based on Glasgow Outcome Scale (GOS) at...περισσότερα »
Revision stapes surgery for lysis of the long process of the incus
Revision stapes surgery for lysis of the long process of the incus: comparing hydroxyapatite bone cement versus malleovestibulopexy and total ossicular replacement prosthesis: AbstractThe objective of the study was to report audiological results in revision stapes surgery, comparing hydroxyapatite (HAP) bone cement, malleovestibular (MV) prosthesis, and total ossicular replacement prosthesis (TORP). The study is a retrospective case review conducted in a tertiary referral center. Patients treated for revision stapes surgery from 2010 to 2014, where a lysis of the long process of th... περισσότερα »
Excitation Patterns of Standard and Steered Partial Tripolar Stimuli in Cochlear Implants
Excitation Patterns of Standard and Steered Partial Tripolar Stimuli in Cochlear Implants: AbstractCurrent steering in partial tripolar (pTP) mode has been shown to improve pitch perception and spectral resolution with cochlear implants (CIs). In this mode, a fraction (*σ*) of the main electrode current is returned within the cochlea and steered between the basal and apical flanking electrodes (with a proportion of *α* and 1 − *α*, respectively). Pitch generally decreases when *α* increases from 0 to 1, although the salience of pitch change varies across CI users. This study aimed ... περισσότερα »
Journal of the Association for Research in Otolaryngology
Increased Spontaneous Otoacoustic Emissions in Mice with a Detached Tectorial Membrane Abstract Mutations in genes encoding tectorial membrane (TM) proteins are a significant cause of human hereditary hearing loss (Hildebrand et al. 2011), and several mouse models have been developed to study the functional significance of this accessory structure in the mammalian cochlea. In this study, we use otoacoustic emissions (OAE), signals obtained from the ear canal that provide a measure of cochlear function, to characterize a mouse in which the TM is detached from the spiral limbus due to ...περισσότερα »
Prophylactic Drug Treatment of Migraine in Children and Adolescents
Prophylactic Drug Treatment of Migraine in Children and Adolescents: An Update: AbstractMigraine as a highly disabling pain condition influences the daily activities of those affected, including children and adolescents. The pathomechanism of migraine is not fully understood, and the different types of prophylactic antimigraine drugs that are applied are not specific for migraine. There is a need for preventive treatment in the event of frequent migraine attacks, an impairment of the quality of life, severe accompanying or aura symptoms, and the failure of acute drug treatment. The... περισσότερα »
Psychological Therapy in Adolescents with Chronic Daily Headache
Psychological Therapy in Adolescents with Chronic Daily Headache: AbstractChronic daily headache is a serious disease, causing significant problems in terms of reduced quality of life and disability, with pain localized to the head (headache) occurring 15 or more days per month for more than 3 months (>180 days per year). Drugs, both used as preventive medications or as pain-killers, are insufficient for the management of these patients; a more global approach has been advocated. This paper reviews existing data concerning different psychological approaches, with a focus on adolesc...περισσότερα »
Outcome of Chronic Daily Headache or Chronic Migraine
Outcome of Chronic Daily Headache or Chronic Migraine: AbstractChronic daily headache (CDH) is a common neurological condition that affects 1–4 % of the general population. Recent epidemiological studies have shown that CDH is mainly represented by chronic migraine (CM). Owing to the frequent headaches, associated symptoms, and comorbid conditions associated with CDH/CM, disability, quality of life (QoL), economic burden, and treatment outcome have become important personal and social issues. There have been several studies assessing the disability, QoL, and economic burden associa...περισσότερα »
Endoscopic Dacryocystorhinostomy (DCR)
Endoscopic Dacryocystorhinostomy (DCR): a comparative study between powered and non-powered technique: Abstract BackgroundDacrocystorhinostomy (DCR) is an operation used to treat nasolacrimal duct obstruction. Essentially there are two approaches: external and endoscopic. Several modalities are used in endoscopic DCR; all aiming to improve success rate, reduce complications, and shorten operative time. Both kerrison punch and drill are widely used in endoscopic DCR with non-conclusive knowledge about differences in operative details as well as on the outcome. The aim of this study...περισσότερα »
Phonomicrosurgery for Vocal Fold Polyp : Postoperative Proton Pump Inhibitor Therapy
Effect of Postoperative Proton Pump Inhibitor Therapy on Voice Outcomes Following Phonomicrosurgery for Vocal Fold Polyp: A Randomized Controlled Study: Abstract Objective To determine the effect of a postoperative proton pump inhibitor (PPI) on voice outcomes after phonomicrosurgery in patients with vocal fold polyp. Study Design A prospective, randomized, controlled study. Settings Tertiary care referral medical center. Participants A total of 48 patients underwent phonomicrosurgery for vocal fold polyps. After surgery, patients were randomized to the PPI group (lansoprazole 15mg t...περισσότερα »
Ageing: (In)flaming susceptibility
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Nature Reviews Cancer 16, 5 (2016). doi:10.1038/nrc.2015.14 Author: Gemma K. Alderton Cancer incidence increases with age, but the mechanisms underlying this effect remain unclear. Henry et al. showed that B cell progenitor cells had defective signalling and metabolism, as well as altered gene expression. These defects were recapitulated in B cell progenitors derived from young […]
Immunohistochemical expression of matrix metalloproteinases in ameloblastomas and pericoronal follicles
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Background Ameloblastoma (AM) is a benign odontogenic neoplasm characterized by local invasiveness and recurrence. We compared the immunohistochemical expression of matrix metalloproteinases in different clinical types of AM as well as in normal odontogenic tissue. Methods Thirteen cases of solid AMs, five cases of unicystic AM and eight pericoronal follicles (PF) were selected and subjected […]
Nanotechnology: Improving drug delivery with algae
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Nature Reviews Cancer 16, 5 (2016). doi:10.1038/nrc.2015.15 Author: Gemma K. Alderton Nanoporous silica-based materials can be used to package drugs that are poorly water soluble. But production of these materials is expensive, so Delalat et al. used the diatom microalga Thalassiosira pseudonana to produce nanoporous biosilica on which is attached an immunoglobulin G (IgG)-binding from […]
Nanotechnology: Improving drug delivery with algae
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Nature Reviews Cancer 16, 5 (2016). doi:10.1038/nrc.2015.15 Author: Gemma K. Alderton Nanoporous silica-based materials can be used to package drugs that are poorly water soluble. But production of these materials is expensive, so Delalat et al. used the diatom microalga Thalassiosira pseudonana to produce nanoporous biosilica on which is attached an immunoglobulin G (IgG)-binding from […]
Neuroblastoma: As a matter of FACT
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Nature Reviews Cancer 16, 2 (2016). doi:10.1038/nrc.2015.11 Author: Safia Danovi Carter, Murray et al. show that MYCN and the histone chaperone FACT are part of a positive feedback loop and that inhibition of FACT with a small molecule leads to tumour regression in a pre-clinical model of MYCN-amplified neuroblastoma. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader […]
NK cells and cancer: you can teach innate cells new tricks
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Nature Reviews Cancer 16, 7 (2016). doi:10.1038/nrc.2015.5 Authors: Maelig G. Morvan & Lewis L. Lanier Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic function that provide host defence against microbial infection and tumours. Here, we review evidence for the role of NK cells in immune surveillance against cancer and […]
Somatic mosaicism: on the road to cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Nature Reviews Cancer 16, 43 (2016). doi:10.1038/nrc.2015.1 Authors: Luis C. Fernández, Miguel Torres & Francisco X. Real Diversity is the basis of fitness selection. Although the genome of an individual is considered to be largely stable, there is theoretical and experimental evidence — both in model organisms and in humans — that genetic mosaicism is […]
Cancer predisposition: Searching for early events
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Nature Reviews Cancer 16, 5 (2016). doi:10.1038/nrc.2015.13 Author: Gemma K. Alderton Zhang et al. examined genetic predisposition to cancer by carrying out whole-exome and whole-genome sequencing of 1,120 patients with cancer who were less than 20 years old. They analysed the sequences of 565 genes that are known to be associated with cancer and were […]
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