Head and Neck Medicine by Alexandros G.Sfakianakis: Απριλίου 2016

Πέμπτη 28 Απριλίου 2016

OtoRhinoLaryngology & Medicine,New Articles,April 28th,2016,a

Breakfast and Other Meal Consumption in Adolescents

alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 8 δευτερόλεπτα

The aim of the study was to evaluate the frequency of breakfast and other meal consumption by adolescents and to assess the relationship between the first and the last meal consumption and sex, body mass index (BMI), and middle school and high school students’ education level. The study was conducted in 2013–2014 among 3009 students […]

The Role of Influenza in the Delay between Low Temperature and Ischemic Heart Disease: Evidence from Simulation and Mortality Data from Japan

Many studies have found that cardiovascular deaths mostly occur within a few days of exposure to heat, whereas cold-related deaths can occur up to 30 days after exposure. We investigated whether influenza infection could explain the delayed cold effects on ischemic heart diseases (IHD) as they can trigger IHD. We hypothesized two pathways between cold […]

Residues in the Distal Heme Pocket of Arabidopsis Non-Symbiotic Hemoglobins: Implication for Nitrite Reductase Activity

It is well-established that plant hemoglobins (Hbs) are involved in nitric oxide (NO) metabolism via NO dioxygenase and/or nitrite reductase activity. The ferrous-deoxy Arabidopsis Hb1 and Hb2 (AHb1 and AHb2) have been shown to reduce nitrite to NO under hypoxia. Here, to test the hypothesis that a six- to five-coordinate heme iron transition might mediate […]

Copper Homeostasis as a Therapeutic Target in Amyotrophic Lateral Sclerosis with SOD1 Mutations

Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease affecting both upper and lower motor neurons, and currently, there is no cure or effective treatment. Mutations in a gene encoding a ubiquitous antioxidant enzyme, Cu,Zn-superoxide dismutase (SOD1), have been first identified as a cause of familial forms of ALS. It is widely accepted that mutant […]

Prototype and Chimera-Type Galectins in Placentas with Spontaneous and Recurrent Miscarriages

Galectins are galactose binding proteins and, in addition, factors for a wide range of pathologies in pregnancy. We have analyzed the expression of prototype (gal-1, -2, -7, -10) and chimera-type (gal-3) galectins in the placenta in cases of spontaneous abortions (SPA) and recurrent abortions (RA) in the first trimester. Fifteen placental samples from healthy pregnancies […]

Gastro-entérite aiguë – résultats provisoires de l’enquête 2014

from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1QCEasZ via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Mycobacterium ulcerans disease (Buruli ulcer): potential reservoirs and vectors

from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1rBPwcE via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Cholesterol levels, not statins, influence colorectal cancer risk https://t.co/BjKY8igLNB https://t.co/o214pNVIe7

Cholesterol levels, not statins, influence colorectal cancer risk https://t.co/BjKY8igLNB https://t.co/o214pNVIe7 from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/725657093609508864 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Anti-tumour necrosis factor therapy is associated with certain subtypes of chronic rhinosinusitis

Research Articles C G Leonard, C Masih, S McDonald, G Taylor, N Maiden, P J Leyden The Journal of Laryngology & Otology,FirstView Article(s), 5 pages Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/245weNY via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Immune signalling in the brain

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα

Novel imaging tools for investigating the role of via ScienceDirect Search: nanodiamond AND fluorescence Publication date: Available online 26 April 2016 *Source:*Brain, Behavior, and Immunity Author(s): Jonathan Henry W Jacobsen, Lindsay M Parker, Arun V Everest-Dass, Erik P Schartner, Georgios Tsiminis, Vasiliki Staikopoulos, Mark R Hutchinson, Sanam Mustafa The importance of neuro-immune interactions in both physiological and pathophysiological states cannot be overstated. As our appreciation for the neuroimmune nature of the brain and spinal cord grows, so does our need to extend ... περισσότερα »

Vancomycin dosing nomograms targeting high serum trough levels

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα

in different populations: pros and cons: Abstract PurposeUtilization of higher doses of vancomycin to achieve the trough concentrations of 15–20 mg/L for complicated infections has been recommended by the Infectious Diseases Society of America clinical practice guideline in recent years. Concerning this recommendation, several nomograms have been constructed targeting this optimal trough level range in different populations of patients. In this review, we have collected available nomograms targeting high trough serum levels of vancomycin, particularly comparing their advantages a...περισσότερα »

Perispinal Delivery of CNS Drugs

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα

Perispinal Delivery of CNS Drugs: AbstractPerispinal injection is a novel emerging method of drug delivery to the central nervous system (CNS). Physiological barriers prevent macromolecules from efficiently penetrating into the CNS after systemic administration. Perispinal injection is designed to use the cerebrospinal venous system (CSVS) to enhance delivery of drugs to the CNS. It delivers a substance into the anatomic area posterior to the ligamentum flavum, an anatomic region drained by the external vertebral venous plexus (EVVP), a division of the CSVS. Blood within the EVVP c...περισσότερα »

Five Factor Personality and Gender on Depressive Symptoms

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα

Direct and Indirect Effects of Five Factor Personality and Gender on Depressive Symptoms Mediated by Perceived Stress: [image: journal.pone.0154140.g001] by Song E. Kim, Han-Na Kim, Juhee Cho, Min-Jung Kwon, Yoosoo Chang, Seungho Ryu, Hocheol Shin, Hyung-Lae Kim This study was designed to investigate associations among five factor personality traits, perceived stress, and depressive symptoms and to examine the roles of personality and perceived stress in the relationship between gender and depressive symptoms. The participants (N = 3,950) were part of a cohort study for health ...περισσότερα »

Dietary intake and risk of asthma in children and adults: protocol for a systematic review and meta-analysis

sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα

Diet has been proposed to modulate the risk of asthma in children and adults. An increasing body of epidemiological studies have been published in the last year investigating the association between dietary i… from Allergy via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1VWl4pz via IFTTT

Lactobacillus acidophilus K301 Inhibits Atherogenesis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα

via Induction of 24 (S), 25-Epoxycholesterol-Mediated ABCA1 and ABCG1 Production and Cholesterol Efflux in Macrophages: [image: journal.pone.0154302.g001] by Yi-Fan Hong, Hangeun Kim, Hye Sun Kim, Woo Jung Park, Joo-Yun Kim, Dae Kyun Chung *Lactobacillus acidophilus* species are well-known probiotics with the beneficial activity of regulating cholesterol levels. In this study, we showed that *L*. *acidophilus* K301 reduced the level of cholesterol through reverse transport in macrophages. *L*. *acidophilus* K301 upregulated the mRNA and protein levels of genes such as ATP-bind...περισσότερα »

Evidence-based treatment of frequent heartburn: the benefits and limitations of over-the-counter medications.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Evidence-based treatment of frequent heartburn: the benefits and limitations of over-the-counter medications.* J Am Assoc Nurse Pract. 2014 Jun;26(6):330-9 Authors: McRorie JW, Gibb RD, Miner PB Abstract PURPOSE: This review summarizes the pharmacological effects of over-the-counter (OTC) heartburn drugs, and the implications for treating frequent heartburn. DATA SOURCES: PubMed and SCOPUS were searched across all years to identify well-controlled, randomized clinical studies that assessed mechanism of action and... περισσότερα »

Association between temporomandibular disorders and obesity

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

Psychological stress can induce altered eating patterns, and studies have indicated that there is a correlation between temporomandibular disorder (TMD) and psychological stress. This study investigated the relationship between TMD and body mass index (BMI) in a large representative sample of the South Korean population using data from the Korea National Health and Nutrition Examination Survey (KNHANES). en and women with TMD showed decreased prevalence of abdominal obesity. Women with TMD had lower age, lower BMI, lower metabolic syndromic waist circumference, lower prevalence of...περισσότερα »

Voice Campaigns in Brazil: Effective Practices in Health Education

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

The aim of this study was to identify the health education practices used during Voice Campaigns in Brazil between 2005 and 2013. from #ENT via xlomafota13 on Inoreader http://ift.tt/1Wsk63o via IFTTT

Influence of deprivation on health-related quality of life of patients with cancer of the head and neck in Merseyside and Cheshire

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

The incidence of cancer of the head and neck, and the outcome of treatment in terms of survival and health-related quality of life (HRQoL), is linked to deprivation. We have explored the association of social deprivation with HRQoL and with fear of recurrence in patients treated for cancer of the head and neck in Merseyside and Cheshire. In 2013, we posted cross-sectional surveys to 805 patients treated for oral, oropharyngeal, or laryngeal tumours. We used the University of Washington quality of life score (UW-QoLv4) to measure HRQoL, a 7-item questionnaire to measure fear of rec...περισσότερα »

Does increasing the number of short implants reduce marginal bone loss in the posterior mandible? A prospective study

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

Marginal bone loss is a concern in the long-term prognosis of short dental implants. The aim of this prospective cohort study was to evaluate the loss when variable numbers of short implants were used in the posterior mandible. The subjects were allocated into three groups according to the number of short implants. The first group was given two, the second three, and the third four. Each patient had radiographs taken immediately after loading and repeated 36 months later. Twenty- three subjects with 65 implants were entered in the three groups. from #ENT via xlomafota13 on Inoread... περισσότερα »

Intermaxillary fixation with sutures: RAI Modification

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

Intermaxillary fixation with the help of screws, arch bars, eyelet wiring, direct interdental wiring,1 buccolingual stabilisation,2 and loop-designed wire,3 is common. All of these techniques take time and require us to manipulate wires, which increases the chances of percutaneous injury to the fingers. We recommend the use of 1-0 polypropylene suture (Prolene, Ethicon) for achieving fixation intraoperatively, and for short-term treatments (Fig. 1). from #ENT via xlomafota13 on Inoreader http://ift.tt/1NVZmub via IFTTT

“Current thinking” articles in BJOMS: are they for everyone?

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

Staying up to date in all aspects of our discipline is essential, both for trainees and consultants, if we are to manage our patients to the best of our abilities in the most up-to-date, evidence-based manner. Treatment by subspecialists is now the norm, and in an increasingly litigious society, updates that reflect current thinking should help us avoid complaints. Unfortunately, in this ever-evolving complex specialty, it is becoming increasingly difficult to remain conversant with the latest guidelines and management protocols, and this is essential for our trainees if they are t... περισσότερα »

Segmental mandibulectomies made easier: a simple drill guide

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

When performing segmental mandibulectomies and reconstruction with free flaps, the use of customised pre-bent titanium reconstruction plates has considerable advantages. from #ENT via xlomafota13 on Inoreader http://ift.tt/1NVZkmb via IFTTT

Electrochemical treatment: an effective way of dealing with extensive venous malformations of the oral and cervicofacial region

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

We describe the results of electrochemical treatment of extensive venous malformations in the oral and cervicofacial region in 29 patients. Platinum needles were inserted into the lesions under general or local anaesthesia, the electrode pitch, voltage, current, and quantity of electricity being 1-1.5cm, 5-8V, 40-60mA, and 50-60C/cm2, respectively. Six months after the treatment, 26 patients had been cured, and in the other three the lesions had decreased by more than 75%. Electrochemical treatment is therefore relatively safe, simple, and highly efficient for the treatment of ext... περισσότερα »

Sampling the Body Odor of Primates: Cotton Swabs Sample Semivolatiles Rather Than Volatiles

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

We assessed the suitability of a frequently used sampling method employing cotton swabs for collecting animal body odor for gas chromatography–mass spectrometry (GC-MS) analysis of volatile organic compounds (VOCs). Our method validation showed that both sampling material and sampling protocols affect the outcome of the analyses. Thus, among the tested protocols swabs of pure viscose baked before use and extracted with hexane had the least blank interferences in GC-MS analysis. Most critical for the recovery of VOCs was the handling time: the significant recovery losses of volatile...περισσότερα »

Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα

In this study, we assessed whether multisystem reactions to egg and extensively-heated (EH) egg during OFCs were associated with a history of multisystem reactions. Records of children, who underwent OFC to eg... from #ENT via xlomafota13 on Inoreader http://ift.tt/1NC2Y9U via IFTTT

Diabetic Neuropathy on Balance and on the Risk of Falls

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα

The Impact of Diabetic Neuropathy on Balance and on the Risk of Falls in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study: by Bogdan Timar, Romulus Timar, Laura Gaiță, Cristian Oancea, Codrina Levai, Diana Lungeanu Introduction Diabetic neuropathy (DN) is a prevalent complication of Type 2 Diabetes Mellitus (T2DM) with a major impact on the health of the affected patient. We hypothesized that mediated by the dysfunctionalities associated with DN’s three major components: sensitive (lack of motion associated sensory), motor (impairments in movement coordination) and...περισσότερα »

BAP1 Immunostain and CDKN2A (p16) FISH Analysis

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα

Background Loss of BAP1 by immunohistochemistry (IHC) and *CDKN2A*(p16) deletion by fluorescence *in situ* hybridization (FISH) have been proposed to distinguish malignant mesothelioma (MM) from atypical reactive mesothelial proliferations (ARMP) in effusions but it is uncertain whether both tests are needed routinely. Methods Paraffin embedded blocks from 67 effusions (32 MM, 35 ARMP) were evaluated with BAP1 IHC. 38 of them (17 MM, 21 ARMP) were also analyzed with *CDKN2A* (p16) FISH. Criteria for MM were absence of BAP1 nuclear staining in >50% of atypical mesothelial cells i... περισσότερα »

Cytopathological features of villous adenoma of the urinary bladder in urine: A rare case report

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα

Villous adenoma of the urinary bladder is a rare tumor that histologically mimics its enteric counterpart. Patients with an isolated villous adenoma have an excellent prognosis, but associated adenocarcinomas can frequently be identified in them as well. There is no literature that discusses the cytopathologic features of villous adenoma. Here we report a case which was diagnosed as villous adenoma histologically, which has been followed up with urine cytology. In urine cytology, many mucin producing cells are recognized. Few cell clusters show glandular formation or arrangement a... περισσότερα »

Interhemispheric functional and structural alterations and their relationships with alertness in unilateral temporal lobe epilepsy

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 10 δευτερόλεπτα

*OBJECTIVE:* Many neuroimaging studies have shown that temporal lobe epilepsy (TLE) is associated with functional and structural abnormalities at speciﬁc brain areas. Unfortunately, relatively limited information has been presented about the alterations of interhemispheric functional and anatomic connectivity in patients with unilateral TLE. In the present study, we investigated interhemispheric functional connectivity using a voxel-mirrored homotopic connectivity (VMHC) method. We further revealed fractional anisotropy (FA) changes in the areas with abnormal VMHC values in TLE pa... περισσότερα »

Inter-Hospital Variability of Postoperative Pain after Tonsillectomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα

Prospective Registry-Based Multicentre Cohort Study: by Orlando Guntinas-Lichius, Katharina Geißler, Marcus Komann, Peter Schlattmann, Winfried Meissner Objectives Although tonsillectomy is one of the most frequent and painful surgeries, the association between baseline and process parameters and postoperative pain are not fully understood. Methods A multicentre prospective cohort study using a web-based registry enrolled 1,527 women and 1,008 men aged 4 to 85 years from 52 German hospitals between 2006 and 2015. Maximal pain (MP) score the first day after surgery on a numeri...περισσότερα »

Peri- and Extrapersonal Space

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα

Complementary Hand Responses Occur in Both Peri- and Extrapersonal Space: [image: journal.pone.0154457.g001] by Tim W. Faber, Michiel van Elk, Kai J. Jonas Human beings have a strong tendency to imitate. Evidence from motor priming paradigms suggests that people automatically tend to imitate observed actions such as hand gestures by performing mirror-congruent movements (e.g., lifting one’s right finger upon observing a left finger movement; from a mirror perspective). Many observed actions however, do not require mirror-congruent responses but afford complementary (fitting) res... περισσότερα »

Tumor Regression and Patterns of Distant Metastasis of T1-T2 Nasopharyngeal Carcinoma with Intensity-Modulated Radiotherapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα

Tumor Regression and Patterns of Distant Metastasis of T1-T2 Nasopharyngeal Carcinoma with Intensity-Modulated Radiotherapy: by Ming-Yao Wu, Xia-Yun He, Chao-Su Hu Purpose To study tumor regression and failure patterns in T1-T2 non-metastatic nasopharyngeal carcinoma (NPC) after intensity-modulated radiotherapy (IMRT). Methods A retrospective analysis of 139 nasopharyngeal carcinoma patients treated with IMRT between January 2005 and December 2010 in our center was performed. According to the AJCC staging system, all primary lesions were attributed to T1 and T2. The prescripti... περισσότερα »

Low-Grade Astrocytomas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα

Anatomical Involvement of the Subventricular Zone Predicts Poor Survival Outcome in Low-Grade Astrocytomas: [image: journal.pone.0154539.g001] by Shuai Liu, Yinyan Wang, Xing Fan, Jun Ma, Wenbin Ma, Renzhi Wang, Tao Jiang The subventricular zone (SVZ) has been implicated in the origination, development, and biological behavior of gliomas. Tumor-SVZ contact is also postulated to be a poor prognostic factor in glioblastomas. We aimed to evaluate the prognostic consequence of the anatomical involvement of low-grade gliomas with the SVZ. To that end, we reviewed 143 patients with ... περισσότερα »

The painful truth: The documentation burden of a trauma surgeon

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

The Journal of Trauma and Acute Care Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1rk8yDW

Snakebite by the Shore Pit Viper (Trimeresurus purpureomaculatus) Treated With Polyvalent Antivenom

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Wilderness & Environmental Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QCpQkf

Self-rated expectations of suicidal behavior predict future suicide attempts among adolescent and young adult psychiatric emergency patients

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Depression and Anxiety from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1rk8wvR

A prospective study of platelet function in trauma patients

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

The Journal of Trauma and Acute Care Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QCpSZq

Objective and self-reported physical activity measures and their association with depression and satisfaction with life in persons with spinal cord injury

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Archives of Physical Medicine and Rehabilitation from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1rk8wfd

The contribution of anterior deltoid ligament to ankle stability in isolated lateral malleolar fractures

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Injury from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QCpSIX

Repetitive transcranial magnetic stimulation as an alternative therapy for dysphagia after stroke: A systematic review and meta-analysis

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Clinical Rehabilitation from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1rk8y6I

Pulley ruptures in rock climbers: outcome of conservative treatment with the pulley-protection splint—a series of 47 cases

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Wilderness & Environmental Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QCpSsl

Decade long trends (2001-2011) in duration of pre-hospital delay among elderly patients hospitalized for an acute myocardial infarction

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Journal of the American Heart Association from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1rk8xQh

A comprehensive approach for the ergonomic evaluation of 13 emergency and transport ventilators

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Respiratory Care from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QCpSsb

An analysis of neurosurgical practice patterns and outcomes for serious to critical traumatic brain injuries in a mature trauma state

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

The Journal of Trauma and Acute Care Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1rk8xzU

Changing demographics and injury profile of new traumatic spinal cord injuries in the United States, 1972-2014

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Archives of Physical Medicine and Rehabilitation from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QCpSbN

High-intensity interval training and moderate-intensity continuous training in ambulatory chronic stroke: a feasibility study

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Physical Therapy from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1rk8xzG

Transitions in the embodied experience after stroke: a grounded theory study

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Physical Therapy from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QCpRVl

Impact of healthcare-associated sepsis on mortality in critically ill infants

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

European Journal of Pediatrics from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1rk8vbi

Emergency cerclage: outcomes, patient selection, and operative considerations

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Clinical Obstetrics and Gynecology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QCpRET

Responsiveness of the balance evaluation systems test (BESTest) in people with subacute stroke

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Physical Therapy from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1rk8u7a

Helicopters and injured kids: improved survival with scene air medical transport in the pediatric trauma population

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

The Journal of Trauma and Acute Care Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QCpOJ7

Low homoarginine levels in the prognosis of patients with acute chest pain

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Journal of the American Heart Association from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1rk8tQI

Optical Coherence Tomography in Multiple Sclerosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Optical Coherence Tomography in Multiple Sclerosis: Semin Neurol 2016; 36: 177-184 DOI: 10.1055/s-0036-1582226 Retinal optical coherence tomography (OCT) has recently become a vital tool for clinicians and researchers in ophthalmology and, increasingly, in neurology. Optical coherence tomography is quickly and easily performed, well-tolerated by patients, and allows high-resolution viewing of unmyelinated axons and other retinal structures in vivo. These factors have led OCT to find favor as a method of quantifying neuroaxonal loss in multiple sclerosis (MS), and the increasing...περισσότερα »

Vision Disturbances in Multiple Sclerosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Vision Disturbances in Multiple Sclerosis: Semin Neurol 2016; 36: 185-195 DOI: 10.1055/s-0036-1579692 Visual disturbances are frequently encountered in multiple sclerosis (MS), and include problems with how affected individuals see the world (afferent visual pathway symptoms) and how their eyes move together (efferent visual pathway disorders). Optic neuritis is the most common afferent visual pathway manifestation of MS, from which visual recovery is often incomplete. Visual field defects caused by lesions in the retrochiasmal or retrogeniculate regions of the afferent visual ... περισσότερα »

Voiding Dysfunction in Multiple Sclerosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα

Semin Neurol 2016; 36(02): 212-218 DOI: 10.1055/s-0035-1571212 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA. Voiding Dysfunction in Multiple Sclerosis Anton Wintner1, *, Michelle M. Kim1, *, Seth K. Bechis1, *, Evgeniy I. Kreydin2 - 1Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts - 2Department of Urology, David Geffen School of Medicine at University of California-Los Angeles, Los Angeles, California Abstract Voiding dysfunction is a common and debilitating consequence of multiple sclerosis ...περισσότερα »

Narrative skills of children treated for brain tumours: The impact of tumour and treatment related variables on microstructure and macrostructure.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 16 δευτερόλεπτα

*Narrative skills of children treated for brain tumours: The impact of tumour and treatment related variables on microstructure and macrostructure.* Brain Inj. 2016 Apr 27;:1-14 Authors: Docking K, Munro N, Marshall T, Togher L Abstract OBJECTIVE: The narrative skills of children with brain tumours were examined. Influence of tumour location, radiotherapy, time post-treatment and presence of hydrocephalus was also investigated, as well as associations between narrative and language abilities. METHOD: Seventeen children (aged 5;6-14;11) treated for brain tumour and their matched c... περισσότερα »

Stroke and aphasia quality-of-life scale-39: Reliability and validity of the Turkish version.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 16 δευτερόλεπτα

*Stroke and aphasia quality-of-life scale-39: Reliability and validity of the Turkish version.* Int J Speech Lang Pathol. 2016 Apr 27;:1-7 Authors: Noyan-ErbaŞ A, Toğram B Abstract PURPOSE: The aim of this study was to adapt the stroke and aphasia quality-of-life scale-39 (SAQoL-39) to the Turkish language and carry out a reliability and validity study of the instrument in a group of patients with aphasia. METHOD: The study was a descriptive study and contained three phases: adaptation of the SAQoL-39 to the Turkish language, administration of the scale to 30 aphasia patients and... περισσότερα »

Children Who Use Communication Aids Instructing Peer and Adult Partners During Play-Based Activity.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 16 δευτερόλεπτα

*Children Who Use Communication Aids Instructing Peer and Adult Partners During Play-Based Activity.* Augment Altern Commun. 2016 Apr 27;:1-15 Authors: Batorowicz B, Stadskleiv K, von Tetzchner S, Missiuna C Abstract Little is known about how children with severe motor impairments who use communication aids provide instructions when given control over interaction. In this study, 35 children - 18 who used communication aids and 17 who used natural speech - were videotaped in play-based activities. Both groups successfully instructed partners to build replications of models the par... περισσότερα »

The Rapid Aspiration Screening in Suspected Stroke Part 2: Initial and Sustained Nurse Accuracy and Reliability.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 16 δευτερόλεπτα

*The Rapid Aspiration Screening in Suspected Stroke Part 2: Initial and Sustained Nurse Accuracy and Reliability.* Arch Phys Med Rehabil. 2016 Apr 23; Authors: Anderson JA, Pathak S, Rosenbek JC, Morgan RO, Daniels SK Abstract OBJECTIVES: The aim of this study was to determine registered nurses' (RNs) ability to obtain and maintain accurate procedural skills and reliable interpretation of the Rapid Aspiration Screening for Suspected Stroke (RAS(3)). DESIGN: Prospective, observation study SETTING: A certified primary stroke center in a major metropolitan facility PARTICIPANTS: A to... περισσότερα »

Dexmedetomidine and Mannitol for Awake Craniotomy in a Pregnant Patient.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 16 δευτερόλεπτα

[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Dexmedetomidine and Mannitol for Awake Craniotomy in a Pregnant Patient.* Anesth Analg. 2015 May;120(5):1099-103 Authors: Handlogten KS, Sharpe EE, Brost BC, Parney IF, Pasternak JJ Abstract We describe the use of dexmedetomidine for an awake neurosurgical procedure in a pregnant patient and quantify the effect of mannitol on intrauterine volume. A 27-year-old woman underwent a craniotomy, with intraprocedural motor and speech mapping, at 20 weeks of gestation. Sedation was maintained with dexmedetomidine. Mannitol... περισσότερα »

Stroke and aphasia quality-of-life scale-39: Reliability and validity of the Turkish version

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 16 δευτερόλεπτα

10.3109/17549507.2015.1126641 AyŞin Noyan-ErbaŞ from Speech via xlomafota13 on Inoreader http://ift.tt/1rkg29Z

Overvibration-induced blood perfusion and vascular permeability changes may lead to vocal edema.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 16 δευτερόλεπτα

*Overvibration-induced blood perfusion and vascular permeability changes may lead to vocal edema.* Laryngoscope. 2016 Apr 27; Authors: Wang J, Devine E, Fang R, Jiang JJ Abstract OBJECTIVES/HYPOTHESIS: To observe blood perfusion and vascular permeability changes under varying vibration frequency exposures. STUDY DESIGN: Animal model. METHODS: Blood perfusion was measured using laser Doppler flowmetry in eight rabbit auricular vessels (four rabbits) under nonvibration, and 62.5-Hz/1-mm, 125-Hz/1-mm, and 250-Hz/0.5-mm vibration frequency/amplitude exposures. Another 12 rabbits were ... περισσότερα »

Tracing Spasmodic Dysphonia: The Source of Ludwig Traube's Priority.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 16 δευτερόλεπτα

*Tracing Spasmodic Dysphonia: The Source of Ludwig Traube's Priority.* Ann Otol Rhinol Laryngol. 2016 Apr 26; Authors: Lorch MP, Whurr R Abstract OBJECTIVES: Since the mid-20th century, one citation is given historical priority as the first description of spasmodic dysphonia (SD): Ludwig Traube's 1871 case of the "spastic form of nervous hoarseness." Our objective is to understand how this case serves as the foundation of understanding laryngeal movement disorders. METHODS: The original German paper was located and translated. Bibliographical and bibliometric methods are used to d...περισσότερα »

The spread of USA300 methicillin-resistant Staphylococcus aureus (MRSA)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα

Systematic surveillance detects multiple silent introductions and household transmission of methicillin-resistant Staphylococcus aureus USA300 in the east of England: *Background.* The spread of USA300 methicillin-resistant *Staphylococcus aureus* (MRSA) across the United States (US) resulted in an epidemic of infections. In Europe, only sporadic cases or small clusters of USA300 infections are described and its prevalence in England is unknown. We conducted prospective surveillance for USA300 in the east of England. *Methods.* We undertook a 12-month prospective observational coho... περισσότερα »

One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα

One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke: Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke.1,2 Since then, there have been major changes in the management of TIA, including urgent management in specialized units, implementation of immediate investigations, and rapid treatment with antithrombotic agents and other stroke-prevention strategies.1–4 Given these changes, the current prognosis of pa...περισσότερα »

High blood mercury levels were associated with dry eye symptoms

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα

Are higher blood mercury levels associated with dry eye symptoms in adult Koreans? A population-based cross-sectional study: Objectives The purpose of this study was to investigate whether blood mercury concentrations associated with the presence of dry eye symptoms in a nationally representative Korean population. Methods Population-based prospective cross-sectional study using the heavy metal data set of the 2010–2012 Korean National Health and Nutrition Examination Survey (KNHANES). A total of 4761 adult Koreans were the eligible population in this study. Of the 7162 survey part...περισσότερα »

Workplace Violence against Health Care Workers

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα

in the United States: [image: nejmra1501998.fp.png_v03] New England Journal of Medicine, Volume 374, Issue 17, Page 1661-1669, April 2016.

IgE in the Diagnosis and Treatment of Allergic Disease

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα

IgE in the Diagnosis and Treatment of Allergic Disease: Abstract Traditionally the concept of allergy implied an abnormal response to an otherwise benign agent (e.g., pollen or food), with an easily identifiable relationship between exposure and the disease. However, there are syndromes where the relationship between exposure to the relevant allergen and the “allergic” disease is not clear. In these cases the presence of specific IgE antibodies can play an important role in identifying the relevant allergen and provide a guide to therapy. Good examples include: chronic asthma an... περισσότερα »

Childhood wheeze and longitudinal phenotypes of wheeze

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα

Sex-specific risk factors for AbstractBackground While sexual dimorphism in wheeze and asthma prevalence are well documented, sex-specific risk factors for wheeze and longitudinal wheeze phenotypes have not been well elucidated. Objective Using a large pre-birth cohort, this study aimed to identify sex-specific risk factors for wheeze from birth through mid-childhood, and identify distinct longitudinal wheeze phenotypes and the sex-specific risk factors associated with these phenotypes. Methods Mothers reported child wheeze symptoms over the past year, approximately yearly on 9 o...περισσότερα »

Frequent heartburn: over-the-counter medications.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα

Evidence-based treatment of frequent heartburn: the benefits and limitations of over-the-counter medications.: [image: http:--media.wiley.com-assets-7315-19-Wi] Authors: McRorie JW, Gibb RD, Miner PB Abstract PURPOSE: This review summarizes the pharmacological effects of over-the-counter (OTC) heartburn drugs, and the implications for treating frequent heartburn. DATA SOURCES: PubMed and SCOPUS were searched across all years to identify well-controlled, randomized clinical studies that assessed mechanism of action and efficacy. CONCLUSIONS: Antacids can transiently neutralize ac... περισσότερα »

Overlapping Functional Gastrointestinal Disorders on the Presentation and Quality of Life of Patients with Erosive Esophagitis and Nonerosive Reflux Disease.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα

[image: http:--misc.karger.com-LinkOutIcons-sk_n] Authors: Lee SW, Chang CS, Lien HC, Peng YC, Wu CY, Yeh HZ Abstract OBJECTIVE: The aim of this study was to investigate the impact of overlapping functional gastrointestinal disorder (FGID) on the quality of life of patients with nonerosive reflux disease (NERD) and erosive esophagitis (EE). MATERIALS AND METHODS: Data from patients with NERD and EE were collected between January 2009 and March 2010. These cases were further stratified into the subgroups of overlapping NERD-functional dyspepsia (FD), NERD-irritable bowel syndrome ... περισσότερα »

Achalasia: current treatment options.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα

Achalasia: current treatment options.: Expert Rev Gastroenterol Hepatol. Authors: Familiari P, Greco S, Volkanovska A, Gigante G, Cali A, Boškoski I, Costamagna G Abstract Achalasia is a rare esophageal motility disorder, characterized by impaired swallow-induced, lower esophageal sphincter (LES) relaxation and defective esophageal peristalsis. Unfortunately, there are no etiological therapies for achalasia. Patients present with dysphagia, chest pain and regurgitation of undigested food, often leading to weight loss. The currently available treatments have the common aim of relie... περισσότερα »

Laparoscopic surgery for esophageal achalasia.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα

Data analyses and perspectives on laparoscopic surgery for esophageal achalasia.: [image: http:--www.wjgnet.com-files-bpg.gif] [image: http:--www.ncbi.nlm.nih.gov-corehtml-pmc] Authors: Tsuboi K, Omura N, Yano F, Hoshino M, Yamamoto SR, Akimoto S, Masuda T, Kashiwagi H, Yanaga K Abstract In general, the treatment methods for esophageal achalasia are largely classified into four groups, including drug therapy using nitrite or a calcium channel blocker, botulinum toxin injection, endoscopic therapy such as endoscopic balloon dilation, and surgery. Various studies have suggested th... περισσότερα »

Recurrence in patients with papillary thyroid carcinoma undergoing modified radical neck dissection

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα

Risk factors for Abstract Background This study evaluated the impact of lymph node-related factors on the risk of and site of recurrence in patients who had papillary thyroid carcinoma with lymph node metastasis in the lateral compartment (classified as pN1b). Methods Patients underwent total thyroidectomy with unilateral modified radical neck dissection for classical papillary thyroid carcinoma. Risk factors for recurrence were evaluated according to the pattern of recurrence. Results A total of 324 patients were included in the study. The median follow-up was 63 (range 14–181) mont...περισσότερα »

Overvibration-induced blood perfusion and vascular permeability changes may lead to vocal edema.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα

Overvibration-induced blood perfusion and vascular permeability changes may lead to vocal edema.: Laryngoscope. 2016 Apr 27; Authors: Wang J, Devine E, Fang R, Jiang JJ Abstract OBJECTIVES/HYPOTHESIS: To observe blood perfusion and vascular permeability changes under varying vibration frequency exposures. STUDY DESIGN: Animal model. METHODS: Blood perfusion was measured using laser Doppler flowmetry in eight rabbit auricular vessels (four rabbits) under nonvibration, and 62.5-Hz/1-mm, 125-Hz/1-mm, and 250-Hz/0.5-mm vibration frequency/amplitude exposures. Another 12 rabbits were ... περισσότερα »

Melanocytic lesions in the central nervous system (CNS)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα

Mutation analysis of metastatic melanomas in the central nervous system: results of a panel of 5 genes in 48 cases.: Clin Neuropathol. 2016 Apr 27; Authors: Gamsizkan M, Yilmaz I, Simsek HA, Onguru O, Griffin A, Tihan T Abstract Melanocytic lesions in the central nervous system (CNS) may be primary to the site but are more commonly metastases from cutaneous primaries. In fact, melanomas are one of the most common malignancies that can metastasize to the brain, and some patients may not have a diagnosis of melanoma prior to the discovery of the CNS lesion. In such cases, identifyin...περισσότερα »

Platelet-cytokine Complex Suppresses Tumour Growth

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα

by Exploiting Intratumoural Thrombin-dependent Platelet Aggregation.: Sci Rep. 2016;6:25077 Authors: Li YT, Nishikawa T, Kaneda Y Abstract Tumours constitute unique microenvironments where various blood cells and factors are exposed as a result of leaky vasculature. In the present study, we report that thrombin enrichment in B16F10 melanoma led to platelet aggregation, and this property was exploited to administer an anticancer cytokine, interferon-gamma induced protein 10 (IP10), through the formation of a platelet-IP10 complex. When intravenously infused, the complex reached pl...περισσότερα »

Radionecrosis versus disease progression in brain metastasis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα

Value of (18)F-DOPA PET/CT/MRI.: Rev Esp Med Nucl Imagen Mol. 2016 Apr ; Authors: Hernández Pinzón J, Mena D, Aguilar M, Biafore F, Recondo G, Bastianello M Abstract The use of (18)F-DOPA PET/CT with magnetic resonance imaging fusion and the use of visual methods and quantitative analysis helps to differentiate between changes post-radiosurgery vs. suspicion of disease progression in a patient with brain metastases from melanoma, thus facilitating taking early surgical action. PMID: 27117985 [PubMed - as supplied by publisher]

Postradiation sarcoma.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα

Photoletter to the editor J Dermatol Case Rep. 2016 ; Authors: Garrido-Colmenero C, Valenzuela-Salas I, Blasco-Morente G, Aneiros-Fernández J, Tercedor-Sánchez J Abstract Postradiation sarcomas are rare and highly malignant tumors which may appear as a consequence of radiotherapy. They may originate on bone or soft tissues.We report the case of a patient who developed a malignant fibrous histiocytoma 35 years after radiotherapy for a melanoma on her right leg. PMID: 27119003 [PubMed]

Oral Amalgam Tattoo Mimicking Melanoma.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα

Oral Amalgam Tattoo Mimicking Melanoma.: N Engl J Med. 2016 Apr 28;374(17):e21 Authors: Vera-Kellet C, Del Barrio-Díaz P Abstract A 49-year-old woman without a personal or family history of melanoma presented with an asymptomatic pigmented lesion on her tongue that was suggestive of oral melanoma. The patient reported that she had undergone a dental procedure 3 months before the appearance of the lesion. PMID: 27119254 [PubMed - as supplied by publisher]

The hnRNP-Htt axis regulates necrotic cell death induced by transcriptional repression through impaired RNA splicing

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα

*The hnRNP-Htt axis regulates necrotic cell death induced by transcriptional repression through impaired RNA splicing* Cell Death and Disease 7, e2207 (April 2016). doi:10.1038/cddis.2016.101 Authors: Y Mao, T Tamura, Y Yuki, D Abe, Y Tamada, S Imoto, H Tanaka, H Homma, K Tagawa, S Miyano & H Okazawa from Cell via ola Kala on Inoreader http://ift.tt/1N2BBG1 via IFTTT

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα

*CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells* Cell Death and Disease 7, e2209 (April 2016). doi:10.1038/cddis.2016.102 Authors: M Drachsler, S Kleber, A Mateos, K Volk, N Mohr, S Chen, B Cirovic, J Tüttenberg, C Gieffers, J Sykora, C R Wirtz, W Mueller, M Synowitz & A Martin-Villalba from Cell via ola Kala on Inoreader http://ift.tt/1TymtPR via IFTTT

MicroRNA-682-mediated downregulation of PTEN in intestinal epithelial cells ameliorates intestinal ischemia–reperfusion injury

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα

*MicroRNA-682-mediated downregulation of PTEN in intestinal epithelial cells ameliorates intestinal ischemia–reperfusion injury* Cell Death and Disease 7, e2210 (April 2016). doi:10.1038/cddis.2016.84 Authors: Z Liu, J Jiang, Q Yang, Y Xiong, D Zou, C Yang, J Xu & H Zhan from Cell via ola Kala on Inoreader http://ift.tt/1N2BD0z via IFTTT

Glutathione peroxidase 1 deficiency attenuates concanavalin A-induced hepatic injury by modulation of T-cell activation

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα

*Glutathione peroxidase 1 deficiency attenuates concanavalin A-induced hepatic injury by modulation of T-cell activation* Cell Death and Disease 7, e2208 (April 2016). doi:10.1038/cddis.2016.95 Authors: D H Lee, D J Son, M H Park, D Y Yoon, S B Han & J T Hong from Cell via ola Kala on Inoreader http://ift.tt/1TymraB via IFTTT

GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington’s disease: involvement of astrocyte–neuron interactions

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα

*GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington's disease: involvement of astrocyte–neuron interactions* Cell Death and Disease 7, e2206 (April 2016). doi:10.1038/cddis.2016.104 Authors: F L'Episcopo, J Drouin-Ouellet, C Tirolo, A Pulvirenti, R Giugno, N Testa, S Caniglia, M F Serapide, G Cisbani, R A Barker, F Cicchetti & B Marchetti from Cell via ola Kala on Inoreader http://ift.tt/1N2BzOv via IFTTT

Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα

*Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death* Cell Death and Disease 7, e2205 (April 2016). doi:10.1038/cddis.2016.93 Authors: F S Salah, M Ebbinghaus, V Y Muley, Z Zhou, K R D Al-Saadi, M Pacyna-Gengelbach, G A O'Sullivan, H Betz, R König, Z-Q Wang, R Bräuer & I Petersen from Cell via ola Kala on Inoreader http://ift.tt/1Tymt2d via IFTTT

Infiltration of F98 glioma cells in Fischer rat brain is temporary stimulated by radiation

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα

10.1080/09553002.2016.1175682 Guillaume Desmarais from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1qXgpqk via IFTTT

Melanocytic naevi (MN)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα

Biologically distinct subsets of naevi: a review.: G Ital Dermatol Venereol. 2016 Apr 27; Authors: Rogers T, Marino ML, Raciti P, Jain M, Busam KJ, Marchetti MA, Marghoob AA Abstract Melanocytic naevi (MN) encompass a range of benign tumours with varying microscopic and macroscopic features. Their development is a multifactorial process under genetic and environmental influences. The clinical importance of MN lies in distinguishing them from melanoma and in recognizing their associations with melanoma risk and cancer syndromes. Historically, the distinction between the different t... περισσότερα »

Thyroid lobectomy is an effective option for unilateral benign nodular disease

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα

Thyroid lobectomy is an effective option for unilateral benign nodular disease: Abstract Objective The use of thyroid lobectomy in the treatment of unilateral, benign nodules is limited by the potential of nodular recurrence in the remaining lobe. This study aimed to assess the rate and clinical impact of nodular recurrence in the contralateral lobe after thyroid lobectomy and to identify predictive factors of recurrence. Design Single-center retrospective study. Patients Records of patients that underwent lobectomy for unilateral thyroid nodules between 1991 and 2010 were reviewed ... περισσότερα »

KIM-1 and NGAL as potential biomarkers for the diagnosis and cancer progression.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*KIM-1 and NGAL as potential biomarkers for the diagnosis and cancer progression.* Postepy Hig Med Dosw (Online). 2016;70:329-36 Authors: Marchewka Z, Tacik A, Piwowar A Abstract On the basis of scientific literature, there is growing evidence that KIM-1 and NGAL are interesting and promising biomarkers not only in acute and chronic inflammatory processes but also in oncogenesis. There are a number of studies which investigate their possible use in diagnosis, treatment and monitoring of therapy effectiveness. The results of recent research suggests that they may play an important... περισσότερα »

Immunomodulatory role of bitter melon extract in inhibition of head and neck squamous cell carcinoma growth.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Immunomodulatory role of bitter melon extract in inhibition of head and neck squamous cell carcinoma growth.* Oncotarget. 2016 Apr 21; Authors: Bhattacharya S, Muhammad N, Steele R, Peng G, Ray RB Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer and leading cause of cancer related mortality worldwide. Despite the advancement in treatment procedures the overall survival rate of patients has not considerably enhanced in the past few decades. Therefore, new strategies to achieve a favorable response for the improvement in the prognosis of HNSCC... περισσότερα »

Glutamic Acid Residues in HIV-1 p6 Regulate Virus Budding and Membrane Association of Gag.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Glutamic Acid Residues in HIV-1 p6 Regulate Virus Budding and Membrane Association of Gag.* Viruses. 2016;8(4) Authors: Friedrich M, Setz C, Hahn F, Matthaei A, Fraedrich K, Rauch P, Henklein P, Traxdorf M, Fossen T, Schubert U Abstract The HIV-1 Gag p6 protein regulates the final abscission step of nascent virions from the cell membrane by the action of its two late (l-) domains, which recruit Tsg101 and ALIX, components of the ESCRT system. Even though p6 consists of only 52 amino acids, it is encoded by one of the most polymorphic regions of the HIV-1 gag gene and undergoes v... περισσότερα »

Overvibration-induced blood perfusion and vascular permeability changes may lead to vocal edema.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

The Efficacy of Intense Pulsed Light Therapy in Postoperative Recovery from Eyelid Surgery.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*The Efficacy of Intense Pulsed Light Therapy in Postoperative Recovery from Eyelid Surgery.* Plast Reconstr Surg. 2016 May;137(5):783e-789e Authors: Linkov G, Lam VB, Wulc AE Abstract BACKGROUND: The purpose of this study was to evaluate the efficacy of postoperative intense pulsed light therapy on patients who undergo bilateral eyelid surgery. METHODS: Patients presenting over a 3-month period for bilateral eyelid surgery were asked to participate in an institutional review board-approved study. Intense pulsed light therapy was administered three times to the same randomly assi...περισσότερα »

Head and Neck Vascular Anomalies: A Practical Case-Based Approach.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Head and Neck Vascular Anomalies: A Practical Case-Based Approach.* Plast Reconstr Surg. 2016 May;137(5):1654 Authors: Adkinson JM PMID: 27119936 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1Ty96ze via IFTTT

Discussion: Comparison of Single and Double Venous Anastomoses in Head and Neck Oncologic Reconstruction Using Free Flaps: A Meta-Analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Discussion: Comparison of Single and Double Venous Anastomoses in Head and Neck Oncologic Reconstruction Using Free Flaps: A Meta-Analysis.* Plast Reconstr Surg. 2016 May;137(5):1595-1596 Authors: Hanasono MM PMID: 27119932 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/26wzznN via IFTTT

Comparison of Single and Double Venous Anastomoses in Head and Neck Oncologic Reconstruction Using Free Flaps: A Meta-Analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Comparison of Single and Double Venous Anastomoses in Head and Neck Oncologic Reconstruction Using Free Flaps: A Meta-Analysis.* Plast Reconstr Surg. 2016 May;137(5):1583-1594 Authors: Chaput B, Vergez S, Somda S, Mojallal A, Riot S, Vairel B, Meresse T, Garrido I, Grolleau JL, de Bonnecaze G Abstract BACKGROUND: Venous insufficiency is the main cause of failure and surgical revision in free flap surgery. Achieving a double venous anastomosis is frequently proposed to improve flap drainage. However, this procedure remains controversial. The authors evaluated, through a meta-analy...περισσότερα »

Interventions to Decrease Postoperative Edema and Ecchymosis after Rhinoplasty: A Systematic Review of the Literature.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Interventions to Decrease Postoperative Edema and Ecchymosis after Rhinoplasty: A Systematic Review of the Literature.* Plast Reconstr Surg. 2016 May;137(5):1448-1462 Authors: Ong AA, Farhood Z, Kyle AR, Patel KG Abstract BACKGROUND: Today, minimally invasive procedures are becoming more popular because of the fast recovery. Rhinoplasty is a common facial plastic surgery procedure that can be associated with significant postoperative morbidities, especially periorbital edema and ecchymosis. The aim of this review is to summarize the results of published literature that studied i... περισσότερα »

Liquid biopsy monitoring uncovers acquired RAS-mediated resistance to cetuximab in a substantial proportion of patients with head and neck squamous cell carcinoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Liquid biopsy monitoring uncovers acquired RAS-mediated resistance to cetuximab in a substantial proportion of patients with head and neck squamous cell carcinoma.* Oncotarget. 2016 Apr 22; Authors: Braig F, Voigtlaender M, Schieferdecker A, Busch CJ, Laban S, Grob T, Kriegs M, Knecht R, Bokemeyer C, Binder M Abstract Resistance to epidermal growth factor receptor (EGFR)-targeted therapy is insufficiently understood in head and neck squamous cell carcinoma (HNSCC), entailing the lack of predictive biomarkers.Here, we studied resistance-mediating EGFR ectodomain and activating RA...περισσότερα »

Neoadjuvant modified TPF (docetaxel, cisplatin, fluorouracil) for patients unfit to standard TPF in locally advanced head and neck squamous cell carcinoma: a study of 48 patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Neoadjuvant modified TPF (docetaxel, cisplatin, fluorouracil) for patients unfit to standard TPF in locally advanced head and neck squamous cell carcinoma: a study of 48 patients.* Oncotarget. 2016 Apr 22; Authors: Fayette J, Fontaine-Delaruelle C, Ambrun A, Daveau C, Poupart M, Ramade A, Zrounba P, Neidhardt EM, Péron J, Diallo A, Céruse P Abstract TPF (docetaxel, cisplatin, fluorouracil) is the standard chemotherapy used for induction in locally advanced head and neck squamous cell carcinoma (LAHNSCC). Its toxicity limits it to younger patients with good functional status and ...περισσότερα »

What are the real waiting times for therapeutic management of head and neck cancer: a study in the general population in the north-west of France.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*What are the real waiting times for therapeutic management of head and neck cancer: a study in the general population in the north-west of France.* Eur Arch Otorhinolaryngol. 2016 Apr 27; Authors: Guizard AV, Dejardin O, Launay L, Bara S, Lapôtre-Ledoux B, Babin E, Launoy G, Ligier K Abstract Head and neck cancers (HNC) have a poor prognosis and a long treatment delay may have a negative impact on this. Some studies have investigated the determinants of this delay but not in the general population and rarely taking into account socio-economic factors. A high-resolution populatio... περισσότερα »

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas.* Oncotarget. 2016 Apr 23; Authors: García-Carracedo D, Ángeles Villaronga M, Álvarez-Teijeiro S, Hermida-Prado F, Santamaría I, Allonca E, Suárez-Fernández L, Victoria Gonzalez M, Balbín M, Astudillo A, Martínez-Camblor P, Su GH, Pablo Rodrigo J, María García-Pedrero J Abstract The PI3K/AKT/mTOR signaling pathway has emerged as one of the most frequently deregulated in head and neck squamous cell carcinomas (HNSCC). Numerous alterations of various upstream and dow... περισσότερα »

Thyroglossal Duct Papillary Thyroid Carcinoma and Synchronous Lingual Thyroid Atypia.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Thyroglossal Duct Papillary Thyroid Carcinoma and Synchronous Lingual Thyroid Atypia.* Case Rep Otolaryngol. 2016;2016:3975924 Authors: Yoo T, Kim Y, Simental A, Inman JC Abstract Thyroglossal duct and lingual thyroid ectopic lesions are exceedingly rare synchronous findings. Papillary thyroid carcinoma of these ectopic thyroid sites is well understood but still a rare finding. This case points to some management nuances in regard to ectopic thyroid screening with imaging and also shows the effectiveness of minimally invasive transoral robotic surgery for lingual thyroid. PMID:...περισσότερα »

Quality of Life in Children with Hearing Impairment: Systematic Review and Meta-analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Quality of Life in Children with Hearing Impairment: Systematic Review and Meta-analysis.* Otolaryngol Head Neck Surg. 2016 Apr 26; Authors: Roland L, Fischer C, Tran K, Rachakonda T, Kallogjeri D, Lieu J Abstract OBJECTIVE: To determine the impact of pediatric hearing loss (HL) on quality of life (QOL). DATA SOURCES: A qualified medical librarian conducted a literature search for relevant publications that evaluate QOL in school-aged children with HL. REVIEW METHODS: Studies were assessed independently by 2 reviewers for inclusion in the systematic review and meta-analysis. RESUL...περισσότερα »

Association between Magnesium Disorders and Hypocalcemia Following Thyroidectomy.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Association between Magnesium Disorders and Hypocalcemia Following Thyroidectomy.* Otolaryngol Head Neck Surg. 2016 Apr 26; Authors: Nellis JC, Tufano RP, Gourin CG Abstract OBJECTIVE: To identify factors associated with postoperative hypocalcemia after thyroid surgery and to understand the relationship among hypocalcemia, length of hospitalization, and costs of care. STUDY DESIGN: Retrospective database analysis. METHODS: Discharge data from the Nationwide Inpatient Sample for 620,744 patients who underwent thyroid surgery from 2001 to 2010 were analyzed through cross-tabulation... περισσότερα »

Effects of Continuous Positive Airway Pressure on Middle Ear Pressure and Acoustic Stapedial Reflex.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Effects of Continuous Positive Airway Pressure on Middle Ear Pressure and Acoustic Stapedial Reflex.* Otolaryngol Head Neck Surg. 2016 Apr 26; Authors: Li J, Li K Abstract OBJECTIVE: This study investigated the effects of continuous positive airway pressure (CPAP) on middle ear pressure and acoustic stapedial reflex and the correlation between CPAP and middle ear pressure. STUDY DESIGN: Prospective cohort study. SETTING: Tertiary hospitals. SUBJECTS AND METHODS: Fifty patients with obstructive sleep apnea-hypopnea syndrome were assigned to the study group, and 50 healthy volunteer...περισσότερα »

Peel strength and interfacial characterization of maxillofacial silicone elastomers bonded to titanium.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα

*Peel strength and interfacial characterization of maxillofacial silicone elastomers bonded to titanium.* Dent Mater. 2016 Apr 22; Authors: Artopoulou II, Chambers MS, Zinelis S, Eliades G Abstract OBJECTIVES: To investigate the effect of three adhesive primers on the morphology, chemistry and peel bond strength of two maxillofacial silicone elastomers with commercially pure titanium (cpTi). METHODS: The effect of three primers (PR2:A-304 Primer/A-320 Bonding Enhancer, PR3:Super Bond, and PR4:Super Glue) on cpTi morphology and chemistry were studied by reflected light polarized mi...περισσότερα »

Anti-tumour necrosis factor therapy is associated with certain subtypes of chronic rhinosinusitis

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 31 δευτερόλεπτα

Research Articles C G Leonard, C Masih, S McDonald, G Taylor, N Maiden, P J Leyden The Journal of Laryngology & Otology,FirstView Article(s), 5 pages Abstract from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/245weNY via IFTTT

Through-Wall Detection with LS-SVM under Unknown Wall Characteristics

One of the main challenges in through-wall imaging (TWI) is the presence of the walls, whose returns tend to obscure the target behind the walls and must be considered and computed in the imaging procedure. In this paper, a two-step procedure for the through-wall detection is proposed. Firstly, an effective clutter mitigation method based on […]

miR-145a-5p Promotes Myoblast Differentiation

MicroRNAs are a class of 18–22-nucleotide noncoding RNAs that posttranscriptionally regulate gene expression and have been shown to play an important role during myoblast differentiation. In this study, we found that the expression of miR-145a-5p was gradually increased during C2C12 myoblast differentiation, and miR-145a-5p inhibitors or mimics significantly suppressed or promoted the relative expression of […]

False Positive B-Cells Crossmatch after Prior Rituximab Exposure of the Kidney Donor

Crossmatching is essential prior to kidney transplantation to confirm compatibility between the donor and the recipient, particularly to prevent acute antibody-mediated rejection. An unexpected positive crossmatch may be obtained in recipients with an autoimmune disease or preexisting antibodies not detected by single-antigen bead array due to complement interference or who have been previously treated by […]

Nonalcoholic Fatty Liver Disease in Canadian First Nations and Non-First Nations Patients

Background. Features of nonalcoholic fatty liver disease (NAFLD) have yet to be described in the Canadian First Nations (FN) population. The aim of this study was to compare the prevalence, severity, and outcome of NAFLD in FN versus non-FN patients at an urban, tertiary care centre. Methods. Adults with NAFLD and no additional liver disease […]

Association Analysis of NALCN Polymorphisms rs1338041 and rs61973742 in a Chinese Population with Isolated Cervical Dystonia

Background. A genome-wide association study (GWAS) demonstrated a possible association between cervical dystonia (CD) and a sodium leak channel, nonselective (NALCN) gene. However, the association between NALCN and CD was largely unknown in Asian population. The present study was carried out to examine the associations between the two single nucleotide polymorphisms (SNPs) rs1338041 and rs61973742 […]

Solitary Fibrous Tumor of the Kidney Developing Local Recurrence

Solitary fibrous tumor (SFT) of the kidney is a rare entity and usually displays a favorable prognosis. We herein report a second case of renal SFT developing local recurrence. A 50-year-old man was referred to our hospital because of a left renal mass. An abdominal CT detected a large renal tumor and radical nephrectomy was […]

Biomechanical, Topological and Chemical Features That Influence the Implant Success of an Urogynecological Mesh: A Review

Synthetic meshes are normally used to treat several diseases in the field of urogynecological surgery. Not-optimal selection of mesh and/or its not-correct implant may increase patient’s pain and discomfort. The knowledge of mechanical behaviour and topological and chemical properties of a mesh plays a fundamental role to minimize patient’s suffering and maximize the implant success. […]

Dermoscopic island (DI) is a dermoscopic clue for the diagnosis of thin melanoma (MM)...Reflectance confocal microscopy for lesions typified by dermoscopic island

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα

Diagnostic accuracy of Abstract Introduction Dermoscopic island (DI) is a dermoscopic clue for the diagnosis of thin melanoma (MM). However, its positive predictive value is about 50% and several naevi with DI are unnecessarily excised. Reflectance confocal microscopy (RCM) is a second level non-invasive imaging tool that increases diagnostic accuracy for MM. Objective To evaluate diagnostic RCM features of pigmented lesions typified by the presence of DI and calculate RCM diagnostic accuracy for MM diagnosis. Methods All lesions with DI were retrieved from a database of 1964 cas...περισσότερα »

BRAFV600E analysis in thyroid FNA

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα

BRAFV600E analysis in thyroid FNA: Xingyun Su,1 Xiaoxia Jiang,1 Xin Xu,1 Weibin Wang,1 Xiaodong Teng,2 Anwen Shao,3 Lisong Teng1 1Department of Surgical Oncology, 2Department of Pathology, First Affiliated Hospital, 3Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China *Abstract:* Fine-needle aspiration (FNA) is a reliable method for preoperative diagnosis of thyroid nodules; however, about 10%–40% nodules are classified as indeterminate. The *BRAFV600E* mutation is the most promising marker for t...περισσότερα »

Exposed, but Not Protected: More Is Needed to Prevent Drug-Resistant Tuberculosis in Healthcare Workers and Students.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα

*Exposed, but Not Protected: More Is Needed to Prevent Drug-Resistant Tuberculosis in Healthcare Workers and Students.* Clin Infect Dis. 2016 May 15;62 Suppl 3:S275-80 Authors: von Delft A, Dramowski A, Sifumba Z, Mosidi T, Xun Ting T, von Delft D, Zumla A Abstract "Occupational MDR-TB" … "XDR-TB" … "Treatment-induced hearing loss": 3 life-changing messages imparted over the phone. Three personal accounts are shared highlighting the false belief held by many healthcare workers (HCWs) and students in low-resource settings-that they are immune to tuberculosis despite high levels of... περισσότερα »

Audiological Results and Quality of Life of Sophono Alpha 2 Transcutaneous Bone-Anchored Implant Users in Single-Sided Deafness

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα

Single-sided deafness (SSD) represents one of the most difficult audiological conditions to rehabilitate. The aim of this prospective study was to evaluate the audiological benefits and quality of life of patients affected by SSD who had previously been users of the Alpha 1® when upgrading them to the Sophono Alpha 2® external processor (Boulder, Colo., USA). Nine patients were included in the study. They underwent physical examination, free-field speech audiometry at 40 and 60 dB, a hearing-in-noise test (Hirsch's test and the squelch test), the Glasgow Benefit Inventory (GBI) ques... περισσότερα »

Prospective, Multicenter Study on Tinnitus Changes after Cochlear Implantation

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα

*Objective:* To investigate the time course of tinnitus changes in patients receiving cochlear implantation (CI) in a prospective, multicenter setting and to determine related factors. *Materials and Methods:* A total of 79 adult patients who underwent CI were included in this study. We used the same questionnaires sequentially 5 times. The questionnaires included the Visual Analog Scale (VAS) for tinnitus severity, the Tinnitus Handicap Inventory (THI), Beck's Depression Index (BDI), and the Brief Encounter Psychosocial Instrument (BEPSI) for stress assessment. *Results:* Tinnitus ... περισσότερα »

Orofaciodigital Syndrome Type 1 and Glomerulocystic Kidney Disease

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα

Daughter and Mother with A 35-year-old woman was admitted to our hospital for evaluation of end-stage renal failure. Diagnostic imaging, including ultrasonography and MRI, showed polycystic kidneys and peribiliary hepatic cysts, but the renal cysts were isointense and her kidneys were smaller than the end-stage kidneys of patients with autosomal dominant polycystic kidney disease. Glomerulocystic kidney disease was diagnosed by renal biopsy. Clinical examination revealed findings such as a missing maxillary canine, lingual anomalies, and brachydactyly.

694-nm fractional Q-switched ruby laser (QSRL) combined with sonophoresis on levorotatory vitamin C for treatment of melasma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα

in Chinese patients: AbstractMelasma is a common acquired and distressing pigmentary disorder presenting to dermatology clinics. It is notably difficult to cure and has a tendency to relapse. The efficacy of classical Q-switched laser in treatment of melasma remains controversial. This study aims to investigate the efficacy and safety of 694-nm fractional QSRL combined with sonophoresis on levorotatory vitamin C for the treatment of melasma patients. Twenty-six patients with melasma were enrolled. Each patient received four to six fractional QSRL treatments at pulse energies of 2.... περισσότερα »

Photodynamic inactivation of a multispecies biofilm using curcumin and LED light

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα

Photodynamic inactivation of a multispecies biofilm using curcumin and LED light: AbstractThis study evaluated the potential of curcumin-mediated antimicrobial photodynamic inactivation (API) on multispecies biofilms of *Candida albicans*, *Candida glabrata*, and *Streptococcus mutans* of different ages. Acrylic samples (*n* = 480) were made with standardized rough surfaces and incubated with bacteria and yeast for 24 or 48 h. API was performed with curcumin (80, 100, 120 μM) and LED light. Additional acrylic samples were treated with curcumin or LED light only. Positive control s... περισσότερα »

Anti-tumour necrosis factor therapy is associated with certain subtypes of chronic rhinosinusitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα

Main ArticleAnti-tumour necrosis factor therapy is associated with certain subtypes of chronic rhinosinusitisC G Leonarda1 c1, C Masiha2, S McDonalda2, G Taylora1, N Maidena2 and P J Leydena1 a1 Department of Otorhinolaryngology, Craigavon Area Hospital, Northern Ireland, UK a2 Department of Rheumatology, Craigavon Area Hospital, Northern Ireland, UK Abstract Background: Chronic rhinosinusitis has many risk factors; however, the effect of anti-tumour necrosis factor therapy has not been investigated in depth. Our experience points to a detrimental clinical effect in overall prevalence...περισσότερα »

The enhancing effect of a laser photochemotherapy with cisplatin or zolendronic acid in primary human osteoblasts and osteosarcoma cells in vitro

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

[image: cover.gif?v=1&s=675d07de70e90879b0ebc822] Background Photodynamic therapies (PDT) have become increasingly popular in the adjuvant treatment of different tumour entities. Chemotherapeutic agents, such as cisplatin may be used in combination with low-level laser therapy (LLLT) as laser photochemotherapy. The aim of this study was to investigate the effect of LLLT on cell bioviability of normal and malignant bone cells under chemotherapeutic conditions with either cisplatin or zolendronic acid *in vitro*. Methods Primary human osteoblasts (HOB) and an osteosarcoma cell line ...περισσότερα »

Photodynamic inactivation of a multispecies biofilm using curcumin and LED light

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

Abstract This study evaluated the potential of curcumin-mediated antimicrobial photodynamic inactivation (API) on multispecies biofilms of *Candida albicans*, *Candida glabrata*, and *Streptococcus mutans* of different ages. Acrylic samples (*n* = 480) were made with standardized rough surfaces and incubated with bacteria and yeast for 24 or 48 h. API was performed with curcumin (80, 100, 120 μM) and LED light. Additional acrylic samples were treated with curcumin or LED light only. Positive control samples received neither light nor curcumin. After API, colony counts were quantifi...περισσότερα »

Efficacy of 694-nm fractional Q-switched ruby laser (QSRL) combined with sonophoresis on levorotatory vitamin C for treatment of melasma in Chinese patients

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

Abstract Melasma is a common acquired and distressing pigmentary disorder presenting to dermatology clinics. It is notably difficult to cure and has a tendency to relapse. The efficacy of classical Q-switched laser in treatment of melasma remains controversial. This study aims to investigate the efficacy and safety of 694-nm fractional QSRL combined with sonophoresis on levorotatory vitamin C for the treatment of melasma patients. Twenty-six patients with melasma were enrolled. Each patient received four to six fractional QSRL treatments at pulse energies of 2.5 to 4 J/cm2 combined ...περισσότερα »

Comments on “light-emitting diode therapy (ledt) before matches prevents increase in creatine kinase with a light dose response in volleyball players”

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

from #Dental via xlomafota13 on Inoreader http://ift.tt/1T6P7Ve via IFTTT

Low-level laser therapy in 3D cell culture model using gingival fibroblasts

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

Abstract Besides extensive data about the effects of low-level laser therapy (LLLT) on different cell types, so far, these results were obtained from monolayer cell culture models, which have limitations in terms of cell morphology and phenotype expression. Therefore, for better in vitro evaluation of the effects of LLLT, this study was performed with a 3D cell culture model, where gingival fibroblasts were seeded in collagen matrix. Cells isolated from a healthy patient were seeded in wells of 24-well plates with culture medium (DMEM) supplemented with 10 % fetal bovine serum and c... περισσότερα »

CO 2 laser surface treatment of failed dental implants for re-implantation: an animal study

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

Abstract The aim of the present study was to evaluate the success rate of failed implants re-implanted after surface treatment with CO2 laser. Despite the widespread use of dental implants, there are many incidents of failures. It is believed that lasers can be applied to decontaminate the implant surface without damaging the implant. Ten dental implants that had failed for various reasons other than fracture or surface abrasion were subjected to CO 2 laser surface treatment and randomly placed in the maxillae of dogs. Three failed implants were also placed as the negative controls a... περισσότερα »

Changes of oxygen status of hair cells for breast cancer presence

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

Abstract The results of differences of wool oxygen status of healthy and cancer carrier mice with spontaneous cancer tumor are represented herein. The investigation was carried out by electronic microscopy and laser-flash photolysis. In the work, two types of breast tumors were researched. Small tumor (nearly 0.5 ÷ 1 cm) was detected by palpation and was well encapsulated. Large tumor was operated when tumor had been disintegrated. It is shown that wool of healthy mouse has dense structure; external layer with large scales is pronounced. At the time, wool of mice with cancer tumor ... περισσότερα »

Stylomandibular fusion that complicates recurrent bilateral ankylosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα

of the temporomandibular joint via British Journal of Oral and Maxillofacial Surgery Publication date: Available online 28 April 2016 *Source:*British Journal of Oral and Maxillofacial Surgery [image: Ossification of the medial pterygoid muscles (blue arrow) in a patient with ...] [image: Polarised light microscopy of a histological section of the right mandibular ...] Author(s): P. Nicol, B. Ruhin, S. Sourice, P. Corre, S. Monnot, G. Baujat, R.H. Khonsari

Seroprevalence and risk factors of severe fever with thrombocytopenia syndrome virus infection

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα

in endemic areas: 10.3109/23744235.2016.1165351 Yong Lyu Abstract *Background*: To determine the seroprevalence, latent infection rate and risk factors for severe fever with thrombocytopenia syndrome virus (SFTSV) infection, a cross-sectional study was conducted in the general population of the Western region of Anhui Province of China from 1 September to 31 December 2014. *Methods*: Twelve villages with the highest rates of endemic SFTS infection were selected from six towns in two counties in the western region of Anhui Province. Blood samples were collected and tested for ... περισσότερα »

Pediatric preoperative risk factors to predict postoperative ICU admission

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα

from a multicenter retrospective study: Summary Background Although some studies have investigated the potential predictors of perioperative mortality, there are few specifically for pediatrics. Objective The aim of the retrospective study was to analyze potential preoperative risk factors and to develop a pediatric preoperative risk prediction score (PRPS), and to predict postoperative ICU admission and the incidence of perioperative death in pediatric patients. Methods Patients who postoperatively admitted to ICU or died (occurred within 30 days after the surgery) from 263 607 ped... περισσότερα »

DISC1 is a coordinator of intracellular trafficking to shape neuronal development and connectivity

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα

Abstract The long, asymmetric and specialised architecture of neuronal processes necessitates a properly regulated transport network of molecular motors and cytoskeletal tracks. This allows appropriate distribution of cargo for correct formation and activity of the synapse, and thus, normal neuronal communication. This communication is impaired in psychiatric disease, and ongoing studies have proposed that DISC1 is an important genetic risk factor for these disorders. The mechanisms by which DISC1 dysfunction might increase propensity to psychiatric disease are not completely unders...περισσότερα »

Using physiological based models for clinical translation, predictive modelling, data interpretation or something in-between?

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα

Abstract Heart disease continues to be a significant clinical problem in Western Society. Predictive models and simulations that integrate physiological understanding with patient information derived from clinical data have huge potential to contribute to improving our understanding of both the progression and treatment of heart disease. In particular they provide the potential to improve patient selection and optimization of cardiovascular interventions across a range of pathologies. Currently a significant proportion of this potential is still to be realised. In this paper we dis... περισσότερα »

Oral pressure therapy (winx) for obstructive sleep apnea: a meta-analysis updating the systematic review

Alexandros G. SfakianakisστοΥπνική Άπνοια και Διαταραχές ΎπνουΠριν από 41 δευτερόλεπτα

from #SleepMedicine via ola Kala on Inoreader http://ift.tt/1Tf2tPz via IFTTT

Photodynamic inactivation of a multispecies biofilm using curcumin and LED light

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 41 δευτερόλεπτα

Efficacy of 694-nm fractional Q-switched ruby laser (QSRL) combined with sonophoresis on levorotatory vitamin C for treatment of melasma in Chinese patients

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 41 δευτερόλεπτα

Comments on “light-emitting diode therapy (ledt) before matches prevents increase in creatine kinase with a light dose response in volleyball players”

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 41 δευτερόλεπτα

from #Dental via xlomafota13 on Inoreader http://ift.tt/1T6P7Ve via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Low-level laser therapy in 3D cell culture model using gingival fibroblasts

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 41 δευτερόλεπτα

CO 2 laser surface treatment of failed dental implants for re-implantation: an animal study

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 41 δευτερόλεπτα

Changes of oxygen status of hair cells for breast cancer presence

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 41 δευτερόλεπτα

Can the angle between optic nerves indicate whether optic chiasm is prefixed, normofixed or postfixed? An anatomical study with radiologic and neurosurgical implications.

Alexandros G. SfakianakisστοHead and NeckΠριν από 47 δευτερόλεπτα

*Can the angle between optic nerves indicate whether optic chiasm is prefixed, normofixed or postfixed? An anatomical study with radiologic and neurosurgical implications.* Surg Radiol Anat. 2016 Apr 25; Authors: Yohannan DG, Krishnapillai R, Suresh R, Ramnarayan S, Peethambaran AK, John NJ Abstract PURPOSE: The objective of this study was to measure the angle (Interneural angle, INA) between intracranial segments of optic nerves (ISON), and to look for any relation between it and the relative anteroposterior location (RAPL) of the optic chiasm (OC)-viz. prefixed, normofixed and ... περισσότερα »

Brain relaxation during craniotomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα

Definition, evaluation, and management of The term ‘brain relaxation’ is routinely used to describe the size and firmness of the brain tissue during craniotomy. The status of brain relaxation is an important aspect of neuroanaesthesia practice and is relevant to the operating conditions, retraction injury, and likely patient outcomes. Brain relaxation is determined by the relationship between the volume of the intracranial contents and the capacity of the intracranial space (i.e. a content–space relationship). It is a concept related to, but distinct from, intracranial pressure... περισσότερα »

Dietary intake and risk of asthma in children and adults

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα

: protocol for a systematic review and meta-analysis Abstract Background Diet has been proposed to modulate the risk of asthma in children and adults. An increasing body of epidemiological studies have been published in the last year investigating the association between dietary intake and asthma. As part of the Evidence-Based Clinical Practice Guideline Task Force on ‘Lifestyle Interventions in Allergy and Asthma’ funded by the European Academy of Allergy and Clinical Immunology, we will use a systematic approach to review the evidence from published scientific literature on... περισσότερα »

Laser photochemotherapy with cisplatin or zolendronic acid in primary human osteoblasts and osteosarcoma cells

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

The enhancing effect of a laser photochemotherapy with cisplatin or zolendronic acid in primary human osteoblasts and osteosarcoma cells in vitro: Background Photodynamic therapies (PDT) have become increasingly popular in the adjuvant treatment of different tumour entities. Chemotherapeutic agents, such as cisplatin may be used in combination with low-level laser therapy (LLLT) as laser photochemotherapy. The aim of this study was to investigate the effect of LLLT on cell bioviability of normal and malignant bone cells under chemotherapeutic conditions with either cisplatin or... περισσότερα »

Visual sequential processing in children with cochlear implants

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 54 δευτερόλεπτα

An exploratory study of via International Journal of Pediatric Otorhinolaryngology Publication date: June 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 85 Author(s): Sneha V. Bharadwaj, Jyutika A. Mehta ObjectiveThe objective of the study was to compare visual sequential processing in school-age children with cochlear implants (CIs) and their normal-hearing (NH) peers. Visual sequential processing was examined using both behavioral and an event-related potential (ERP) measures.MethodsEighteen children with CIs and nineteen children who had hearing within... περισσότερα »

Surgical correction of bifid nose by combined Millard forked flap with external rhinoplasty

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 54 δευτερόλεπτα

Surgical correction of bifid nose via International Journal of Pediatric Otorhinolaryngology Publication date: July 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 86 Author(s): Ali Tawfik, Hossam Elsayed El-Sisi, Ahmed Musaad Abd El-fattah ObjectivesEvaluation of the aesthetic outcome and functional aspect after surgical correction of bifid nose by combined Millard forked flap with external rhinoplasty.BackgroundBifid nose is a rare congenital anomaly that results during facial development but the explicit mechanism is not clearly understood. Clinical findi... περισσότερα »

Diphtheria is a respiratory infectious disease of childhood

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα

Diphtheria: It is still prevalent!!! via International Journal of Pediatric Otorhinolaryngology Publication date: July 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 86 Author(s): Avani Jain, Sunil Samdani, Vinod Meena, Man Prakash Sharma BackgroundDiphtheria is a respiratory infectious disease of childhood. It is a fatal disease and may cause complications if not recognized early and treated properly. Despite availability of effective vaccination it continues to be reported from many parts of the world particularly developing countries.ObjectiveTo assess t... περισσότερα »

Computational fluid dynamics for the assessment of upper airway changes in skeletal Class III patients treated with mandibular setback surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα

Article Citation: Darshit H. Shah, Ki Beom Kim, Mark W. McQuilling, Reza Movahed, Ankit H. Shah, and Yong I. Kim (2016) Computational fluid dynamics for the assessment of upper airway changes in skeletal Class III patients treated with mandibular setback surgery. The Angle Orthodontist In-Press. *doi:* http://dx.doi.org/10.2319/122715-892.1 ONLINE AHEAD OF PRINT Computational fluid dynamics for the assessment of upper airway changes in skeletal Class III patients treated with mandibular setback surgery *Darshit H. Shah a; Ki Beom Kim b; Mark W. McQuilling c; Reza Movahed d; Ankit H. Sh... περισσότερα »

Tinnitus Changes after Cochlear Implantation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα

Prospective, Multicenter Study on : *Objective:* To investigate the time course of tinnitus changes in patients receiving cochlear implantation (CI) in a prospective, multicenter setting and to determine related factors. *Materials and Methods:* A total of 79 adult patients who underwent CI were included in this study. We used the same questionnaires sequentially 5 times. The questionnaires included the Visual Analog Scale (VAS) for tinnitus severity, the Tinnitus Handicap Inventory (THI), Beck's Depression Index (BDI), and the Brief Encounter Psychosocial Instrument (BEPSI) for stre... περισσότερα »

Sophono Alpha 2 Transcutaneous Bone-Anchored Implant

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα

Audiological Results and Quality of Life of Sophono Alpha 2 Transcutaneous Bone-Anchored Implant Users in Single-Sided Deafness: Single-sided deafness (SSD) represents one of the most difficult audiological conditions to rehabilitate. The aim of this prospective study was to evaluate the audiological benefits and quality of life of patients affected by SSD who had previously been users of the Alpha 1® when upgrading them to the Sophono Alpha 2® external processor (Boulder, Colo., USA). Nine patients were included in the study. They underwent physical examination, free-field speech a... περισσότερα »

Low permeability styrene butadiene rubber/boehmite nanocomposites modified with tannic acid

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα

Publication date: 5 August 2016 *Source:*Materials & Design, Volume 103 Author(s): Zhenghai Tang, Chengfeng Zhang, Lixin Zhu, Baochun Guo Layered inorganics are promising in the fabrication of elastomeric nanocomposites with enhanced barrier property. Recently, boehmite (BM) nanoplatelets have emerged as alternative layered inorganics to clays and double hydroxylates as the functional reinforcement for rubbers. In the present paper, natural tannic acid (TA) is introduced as a novel interfacial modifier in BM-filled styrene–butadiene rubber (SBR) nanocomposites. The modification mech... περισσότερα »

Modification of interactions in polypropylene/lignosulfonate blends

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα

Publication date: 5 August 2016 *Source:*Materials & Design, Volume 103 Author(s): Brúnó Bozsódi, Vivien Romhányi, Piroska Pataki, Dávid Kun, Károly Renner, Béla Pukánszky Polypropylene (PP)/lignin blends were prepared in a wide composition range (0–70vol%) from a PP homopolymer and two lignosulfonates of different compositions by homogenization in an internal mixer and compression molding. Thermodynamic considerations and dynamic mechanical analysis (DMTA) were used for the estimation of interactions and miscibility, while mechanical properties were characterized by tensile testing... περισσότερα »

Tensile properties and microstructural evolution of Zircaloy-4 processed through rolling at different temperatures

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα

Publication date: 5 August 2016 *Source:*Materials & Design, Volume 103 Author(s): Devasri Fuloria, Nikhil Kumar, Sunkulp Goel, R. Jayaganthan, S. Jha, D. Srivastava The effect of rolling at different temperatures and deformation strains on the variation in hardness and tensile properties of Zircaloy-4 has been investigated in the present work. The initial hot extruded and annealed Zircaloy-4 was subjected to various rolling reductions of 25%, 50%, 70%, and 90% at room (298K) and liquid nitrogen (77K) temperatures along extrusion and transverse directions of the as-received bar, res... περισσότερα »

Second order hierarchical sandwich structure made of self-reinforced polymers by means of a continuous folding process

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα

Publication date: 15 July 2016 *Source:*Materials & Design, Volume 102 Author(s): M.N. Velea, C. Schneider, S. Lache One typical way to obtain higher stiffness and strength to weight ratios within structural applications is to use sandwich structures containing lightweight cellular cores. In this study a novel second order hierarchical sandwich structure and its manufacturing principle are described. The whole hierarchical structure is made of a fully recyclable material – different forms of poly-ethylene terephthalate (PET): PET matrix, reinforced with PET fibres (Self reinforced -... περισσότερα »

One-step growth of lanthanoid metal-organic framework (MOF) films under solvothermal conditions for temperature sensing

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα

[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC01407K, Communication Xue Liu, Wen Tian Fu, Elisabeth Bouwman A one-step direct solvothermal synthesis of an Ln metal-organic framework (MOF) film is reported. The LnHL (Ln=Tb and Gd) films that were deposited on a Gd2O3 subtrate are continuous and... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1pJvqv1 via IFTTT

The enhancing effect of a laser photochemotherapy with cisplatin or zolendronic acid in primary human osteoblasts and osteosarcoma cells in vitro

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα

The enhancing effect of a laser photochemotherapy with cisplatin or zolendronic acid in primary human osteoblasts and osteosarcoma cells in vitro

Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 1 ώρα

SPEECH THERAPY INTERVENTION IN MORBIDLY OBESE UNDERGOING FOBI-CAPELL GASTROPLASTY METHOD.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα

*SPEECH THERAPY INTERVENTION IN MORBIDLY OBESE UNDERGOING FOBI-CAPELL GASTROPLASTY METHOD.* Arq Bras Cir Dig. 2016 Mar;29(1):43-47 Authors: Gonçalves RF, Zimberg E Abstract BACKGROUND: The rehabilitation of complications related to oral feeding, resulting from gastroplasty is the competence of the speech therapist, to intervene in mastication and swallowing functions, aiming at quality of life. AIM: Check in the postoperative period the efficiency of stimulation, independent judges in readiness for re-introduction of solid food in morbidly obese undergoing gastroplasty. METHOD: C... περισσότερα »

High-Resolution Manometry in Clinical Practice.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα

*High-Resolution Manometry in Clinical Practice.* Gastroenterol Hepatol (N Y). 2015 Jun;11(6):374-84 Authors: Carlson DA, Pandolfino JE Abstract High-resolution manometry (HRM) is the primary method used to evaluate esophageal motor function. Displayed and interpreted by esophageal pressure topography (EPT), HRM/ EPT provides a detailed assessment of esophageal function that is useful in the evaluation of patients with nonobstructive dysphagia and before foregut surgery. Esophageal motility diagnoses are determined systematically by applying objective metrics of esophageal sphinc...περισσότερα »

Biomechanics of Pharyngeal Deglutitive Function Following Total Laryngectomy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα

*Biomechanics of Pharyngeal Deglutitive Function Following Total Laryngectomy.* Otolaryngol Head Neck Surg. 2016 Apr 26; Authors: Zhang T, Szczesniak M, Maclean J, Bertrand P, Wu PI, Omari T, Cook IJ Abstract OBJECTIVE: Postlaryngectomy, pharyngeal weakness, and pharyngoesophageal junction (PEJ) restriction are the candidate mechanisms of dysphagia. The aims were, in laryngectomees, whether (1) hypopharyngeal propulsion is reduced and/or PEJ resistance is increased, (2) dilatation improves dysphagia, and (3) whether symptomatic improvement correlates with reduced PEJ resistance.... περισσότερα »

Penetrating Neck Trauma: An Unusual Case Presentation and Review of the Literature.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα

*Penetrating Neck Trauma: An Unusual Case Presentation and Review of the Literature.* Ann Otol Rhinol Laryngol. 2016 Apr 26; Authors: McCrary HC, Nielsen TJ, Goldstein SA Abstract OBJECTIVES: The aim of this report is to describe a case of a retained projectile metal object to the neck that occurred after airbag deployment during a motor vehicle accident. METHODS: Case report with literature review. RESULTS: After a motor vehicle accident on the interstate, a 19-year-old man presents to the emergency department for several open extremity fractures, a neck laceration, and a C1 late... περισσότερα »

Prospective analysis of functional swallowing outcome after resection of T2 glottic carcinoma using transoral laser surgery and external vertical hemilaryngectomy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα

*Prospective analysis of functional swallowing outcome after resection of T2 glottic carcinoma using transoral laser surgery and external vertical hemilaryngectomy.* Eur Arch Otorhinolaryngol. 2016 Apr 27; Authors: Nasef HO, Thabet H, Piazza C, Del Bon F, Eid M, Banna ME, Nicolai P Abstract 56 patients affected by T2 glottic carcinoma were treated in two institutes using transoral laser microsurgery (TLM) in 40 cases and vertical hemilaryngectomy in 16 cases between September 2012 and September 2015. In the TLM group, different subtypes of type V cordectomy were used according to... περισσότερα »

The Rapid Aspiration Screening in Suspected Stroke Part 1: Development and Validation.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα

*The Rapid Aspiration Screening in Suspected Stroke Part 1: Development and Validation.* Arch Phys Med Rehabil. 2016 Apr 23; Authors: Daniels SK, Pathak S, Rosenbek JC, Morgan RO, Anderson JA Abstract OBJECTIVES: To develop and validate a nurse-administered screening tool to identify aspiration risk in patients with suspected stroke. DESIGN: Validity study comparing evidence-based swallowing screening items with videofluoroscopic swallowing study (VFSS). SETTINGS: The study was completed in a certified primary stroke center in a major metropolitan medical facility. PARTICIPANTS: Co...περισσότερα »

Antimicrobial cathelicidin peptide LL-37 inhibits the pyroptosis of macrophages and improves the survival of polybacterial septic mice

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 1 ώρα

LL-37 is the only known member of the cathelicidin family of antimicrobial peptides in humans. In addition to its broad spectrum of antimicrobial activities, LL-37 can modulate various inflammatory reactions. We previously revealed that LL-37 suppresses the LPS/ATP-induced pyroptosis of macrophages *in vitro* by both neutralizing the action of LPS and inhibiting the response of P2X7 (a nucleotide receptor) to ATP. Thus, in this study, we further evaluated the effect of LL-37 on pyroptosis *in vivo* using a cecal ligation and puncture (CLP) sepsis model. As a result, the intravenou... περισσότερα »

TLR7 and TLR9 ligands regulate antigen presentation by macrophages

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 1 ώρα

The toll-like receptors (TLRs) are important innate receptors recognizing potentially pathogenic material. However, they also play a significant role in the development of Alzheimer's disease, cancer, autoimmunity and the susceptibility to viral infections. Macrophages are essential for an effective immune response to foreign material and the resolution of inflammation. In these studies, we examined the impact of different TLR ligands on macrophage cell function. We demonstrate that stimulation of all TLRs tested increases the phagocytosis of apoptotic cells by macrophages. TLR7 a...περισσότερα »

ACCURATE DIAGNOSIS OF THYROID NODULES: A REVIEW OF DIAGNOSTIC DILEMMAS ON THYROID FINE-NEEDLE ASPIRATION BIOPSIES.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*ACCURATE DIAGNOSIS OF THYROID NODULES: A REVIEW OF DIAGNOSTIC DILEMMAS ON THYROID FINE-NEEDLE ASPIRATION BIOPSIES.* Georgian Med News. 2016 Mar;(252):89-95 Authors: Barabadze E, Burkadze G, Munjishvili V Abstract FNA biopsy is well known method for the first step evaluation of thyroid nodules, it is the "gold standard" for diagnosis and surgical approach of nodular goiter. Despite the high sensitivity and specificity of the method there are grey zone in the diagnosis of thyroid nodules, mainly due to the heterogeneous group of Bethesda category AUS/FLUS. There are also some diff... περισσότερα »

[Thyroid nodules - Indication for surgery?]

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*[Thyroid nodules - Indication for surgery?]* MMW Fortschr Med. 2016 Feb;158(3):51-54 Authors: Ladurner R, Beuschlein F, Hallfeldt K, Angele M, Werner J, Sommerey S PMID: 27119700 [PubMed - as supplied by publisher] from pubmed: thyroid cancer http://ift.tt/1qWZFzF via IFTTT

Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer.* Int J Endocrinol. 2016;2016:9570171 Authors: Liou MJ, Tsang NM, Hsueh C, Chao TC, Lin JD Abstract Background. The aims of this study were to analyze the clinical characteristics of SPM in patients with well-differentiated thyroid cancer and to determine the long-term prognosis in patients with double malignancies. Materials and Methods. We retrospectively analyzed 2,864 patients with well-differentiated thyroid cancer and a mean age of 44.0 ± 14.4 years. Of these, 200 (7.0%) ...περισσότερα »

Association between Magnesium Disorders and Hypocalcemia Following Thyroidectomy.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

Calibration of PET/CT scanners for multicenter studies on differentiated thyroid cancer with (124)I.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*Calibration of PET/CT scanners for multicenter studies on differentiated thyroid cancer with (124)I.* EJNMMI Res. 2016 Dec;6(1):39 Authors: Kist JW, van der Vlies M, Hoekstra OS, Greuter HN, de Keizer B, Stokkel MP, V Vogel W, Huisman MC, van Lingen A Abstract BACKGROUND: Studies on imaging of differentiated thyroid cancer (DTC) using (124)I often require a multicenter approach, as the prevalence of DTC is low. Calibration of participating scanners is required to obtain comparable quantification. As determination of a well-defined range of recovery coefficients is complicated fo... περισσότερα »

Thyroid cancer subtype downgraded to non-cancer.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*Thyroid cancer subtype downgraded to non-cancer.* Lancet Oncol. 2016 Apr 21; Authors: Tanday S PMID: 27118318 [PubMed - as supplied by publisher] from pubmed: thyroid cancer http://ift.tt/1qWZF2y via IFTTT

Usefulness of Measuring Thyroid Stimulating Antibody at the Time of Antithyroid Drug Withdrawal for Predicting Relapse of Graves Disease.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*Usefulness of Measuring Thyroid Stimulating Antibody at the Time of Antithyroid Drug Withdrawal for Predicting Relapse of Graves Disease.* Endocrinol Metab (Seoul). 2016 Apr 25; Authors: Kwon H, Kim WG, Jang EK, Kim M, Park S, Jeon MJ, Kim TY, Ryu JS, Shong YK, Kim WB Abstract BACKGROUND: Hyperthyroidism relapse in Graves disease after antithyroid drug (ATD) withdrawal is common; however, measuring the thyrotropin receptor antibody (TRAb) at ATD withdrawal in order to predict outcomes is controversial. This study compared measurement of thyroid stimulatory antibody (TSAb) and th...περισσότερα »

Risk factors for malignancy in systemic sclerosis patients.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*Risk factors for malignancy in systemic sclerosis patients.* Clin Rheumatol. 2016 Apr 27; Authors: Kaşifoğlu T, Yaşar Bilge Ş, Yıldız F, Özen G, Pehlivan Y, Yılmaz N, Tarhan F, Yılmaz S, Küçük A, Emmungil H, Koca SS, Çınar M, Direskeneli H, Erken E, Can G, Özmen M, Gönüllü E, Kisacik B, Aksu K, Karadağ O, Kasifoglu N, Arslantas D, Sahin F, Keser G, Yavuz S, Birlik M, Onat AM Abstract Systemic sclerosis (SSc) is an autoimmune connective tissue disease with multisystem involvement. An increased incidence of cancer in SSc patients compared with the general population has been report... περισσότερα »

Prognostic impact of incomplete surgical clearance of radioiodine sensitive local lymph node metastases diagnosed by post-operative (124)I-NaI-PET/CT in patients with papillary thyroid cancer.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*Prognostic impact of incomplete surgical clearance of radioiodine sensitive local lymph node metastases diagnosed by post-operative (124)I-NaI-PET/CT in patients with papillary thyroid cancer.* Eur J Nucl Med Mol Imaging. 2016 Apr 27; Authors: Sabet A, Binse I, Grafe H, Ezziddin S, Görges R, Poeppel TD, Bockisch A, Rosenbaum-Krumme SJ Abstract PURPOSE: Nodal involvement is an independent risk factor of recurrence in papillary thyroid cancer (PTC). Neither the international guidelines nor the recently introduced ongoing risk adaptation concept consider the extent of initial surgi...περισσότερα »

Clinical and Pathologic Predictors of Lymph Node Metastasis and Recurrence in Papillary Thyroid Microcarcinoma.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*Clinical and Pathologic Predictors of Lymph Node Metastasis and Recurrence in Papillary Thyroid Microcarcinoma.* Thyroid. 2016 Apr 26; Authors: Siddiqui S, White MG, Antic T, Grogan RH, Angelos P, Kaplan EL, Cipriani NA Abstract BACKGROUND: The treatment for patients with papillary thyroid microcarcinoma (PTMC) is controversial because PTMC is often found incidentally and its prognosis is very good. Lymph node metastasis is one of the main predictors of recurrence and survival. This retrospective study aimed to identify clinical and pathologic factors that increase the risk of ...περισσότερα »

Impact of central node dissection on postoperative morbidity in pediatric patients with suspected or proven thyroid cancer.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*Impact of central node dissection on postoperative morbidity in pediatric patients with suspected or proven thyroid cancer.* Surgery. 2016 Apr 22; Authors: Machens A, Elwerr M, Thanh PN, Lorenz K, Schneider R, Dralle H Abstract BACKGROUND: Pediatric risk factors for postoperative morbidity after central node dissection are ill-defined. METHODS: This outcome study aimed to evaluate operative morbidity in patients aged ≤18 years after total thyroidectomy with or without central node dissection for suspected or proven thyroid cancer. RESULTS: Included were 102 patients with hereditar... περισσότερα »

Cervical esophageal cancer: a gap in cancer knowledge.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

*Cervical esophageal cancer: a gap in cancer knowledge.* Ann Oncol. 2016 Apr 26; Authors: Hoeben A, Polak J, Van De Voorde L, Hoebers F, Grabsch HI, de Vos-Geelen J Abstract BACKGROUND: The aim of this systematic review is to provide an overview of the diagnosis, treatment options and treatment related complications of cervical esophageal carcinoma (CEC) and subsequently provide recommendations to improve quality of care. DESIGN: Studies were identified in PubMed, EMBASE and Web of Science. A total of 107 publications fulfilled the inclusion criteria and were included. RESULTS: C... περισσότερα »

Comparison of Diagnostic Accuracy of Real-Time Elastography and Shear Wave Elastography in Differentiation Malignant From Benign Thyroid Nodules.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

Related Articles *Comparison of Diagnostic Accuracy of Real-Time Elastography and Shear Wave Elastography in Differentiation Malignant From Benign Thyroid Nodules.* Medicine (Baltimore). 2015 Dec;94(52):e2312 Authors: Tian W, Hao S, Gao B, Jiang Y, Zhang S, Gu L, Luo D Abstract Thyroid nodules are relatively more prevalent in iodine-deficiency area, and the incidence increased sharply in the past decade in these areas. Workup of malignant from benign nodules in clinic was the main problem for managing thyroid nodules.An overall search for the articles about the diagnostic perform... περισσότερα »