Staphylococcus aureus‐derived extracellular vesicles induce monocyte recruitment by activating human dermal microvascular endothelial cells in vitro

Clinical &Experimental Allergy, Volume 0, Issue ja, -Not available-.


https://ift.tt/2y2AKAV

Updates on the surface antigens of basophils: CD16 on basophils of patients with respiratory or insect venom allergy and the rejection of CD203c and CD63 externalization decoupling by bisindolylmaleimides

Clinical &Experimental Allergy, Volume 0, Issue ja, -Not available-.


https://ift.tt/2yd7Eyc

Early‐life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitisation

Clinical &Experimental Allergy, Volume 0, Issue ja, -Not available-.


https://ift.tt/2y0mOYi

Agriculture Occupational Exposures and Factors Affecting Health Effects

Abstract

Purpose of Review

Agriculture environments contain a variety of inflammatory aerosols that may increase risk for lung inflammation and disease in exposed individuals. In addition, epidemiological studies have also identified protective effects of rural environments and farming exposures.

Recent Findings

In this review, we will discuss recent literature published since 2016 that investigates the impact of differing agricultural exposures on respiratory health.

Summary

Discussions include the impact of farming modernization, education, and personal protective equipment usage among workers, timing and duration in mediating lung health outcomes, and population studies investigating the association between exposure and risk for numerous lung diseases.

https://ift.tt/2Nq2AvN

The Multifaceted B Cell Response in Allergen Immunotherapy

Abstract

While allergen immunotherapy (AIT) for IgE-mediated diseases holds curative potential, the considerable heterogeneity in clinical outcomes may relate to the complex mechanisms of tolerance. The regulation of humoral immunity by AIT contributes to the suppression of allergic responses. Recent findings have revealed novel roles for IgA and IgG antibodies in the induction of tolerance. These mechanisms synergize with their ability to block allergen-IgE binding and mediate inhibitory signaling of effector cells of the allergic response. In addition, the regulatory activity of B cells in AIT extends beyond IL-10 secretion and induction of IgG₄. Here, we review the evolution of the B cell response during AIT with special emphasis on the novel protective mechanisms entailing humoral immunity.

https://ift.tt/2OFxGEt

Burkitt lymphoma of the ovaries mimicking sepsis: a case report and review of the literature

It is not unusual for systemic diseases to mimic sepsis and, in any case, the clinician should thoroughly investigate this possibility.

https://ift.tt/2pB4sZa

Food‐induced fatal anaphylaxis: from epidemiological data to general prevention strategies

Clinical &Experimental Allergy, Volume 0, Issue ja, -Not available-.


https://ift.tt/2Ryk8tc