18F-FDG PET/CT Imaging of Metastatic Testicular Choriocarcinoma Mimicking Gastric Cancer which Initial Symptom is Melena

xlomafota13 shared this article with you from Inoreader 18F-FDG PET/CT Imaging of Metastatic Testicular Choriocarcinoma Mimicking Gastric Cancer which Initial Symptom is Melena Via Mol Imaging Radionucl Ther Related Articles 18F-FDG PET/CT Imaging of Metastatic Testicular Choriocarcinoma Mimicking Gastric Cancer which Initial Symptom is Melena Mol Imaging Radionucl Ther. 2021 02 09;30(1):47-49 Authors: Göksel S, Akın S, Akdoğan RA, Rakıcı S, Abdioğlu GY, Ayvaz MA Abstract Gastric metastasis of choriocarcinoma is rarely reported in the literature. This case report presents the case of multiple metastatic testicular choriocarcinoma mimicking gastric cancer, with melena as the initial symptom. In this case, 18fluorine-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) showed that the testis was the primary focus. The contribution of PET/CT is significant to primary focus detection in metastatic diseases of unknown primary origin that presented gastrointestinal bleeding. In addition to its use in staging of testicular carcinoma, PET/CT provides significant benefit in evaluating patients with increased levels of tumor markers and in detecting recurrence. PMID: 33586408 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Somatostatin Receptor Scintigraphy in a Patient with Myocarditis

xlomafota13 shared this article with you from Inoreader Somatostatin Receptor Scintigraphy in a Patient with Myocarditis Via Mol Imaging Radionucl Ther Related Articles Somatostatin Receptor Scintigraphy in a Patient with Myocarditis Mol Imaging Radionucl Ther. 2021 02 09;30(1):50-53 Authors: Amini A, Dehdar F, Jafari E, Gholamrezanezhad A, Assadi M Abstract We report a case of myocarditis imaged with technetium-99m octreotide cardiac single-photon emission computed tomography which showed diffuse uptake in the myocardium, indicating inflammatory reaction to myocardial damage. Somatostatin receptor scintigraphy of the heart could be considered in patients with suspected cardiac inflammation. This could facilitate early diagnosis and guide appropriate treatment. PMID: 33586409 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Small-angle Compton Scatter Artifact in Tc-99m-IDA Hepatobiliary Scintigraphy Resulting in the Breast Overlying the Liver in Planar Dynamic Imaging.

xlomafota13 shared this article with you from Inoreader Small-angle Compton Scatter Artifact in Tc-99m-IDA Hepatobiliary Scintigraphy Resulting in the Breast Overlying the Liver in Planar Dynamic Imaging. Via Mol Imaging Radionucl Ther Related Articles Small-angle Compton Scatter Artifact in Tc-99m-IDA Hepatobiliary Scintigraphy Resulting in the Breast Overlying the Liver in Planar Dynamic Imaging. Mol Imaging Radionucl Ther. 2021 Feb 09;30(1):54-56 Authors: Qutbi M Abstract Compton scatter photons are generally considered problematic in nuclear medicine imaging. Therefore, efforts are being made to minimize the involvement of these photons by employing some special strategies in daily practice. Basically, photons scattering at a small angle and traveling in the proper direction stand a chance of getting recorded and thereby participate in the image formation. These photons may create artifactual hot spots in the vicinity of a region with high concentration of radioactivity. The present study focuses on the negative impact of such photons during routine imaging in clinical setting, through an artifact detected in technetium-99m-IDA hepatobiliary scintigraphy, with the purpose of highlighting this issue to the nuclear medicine practitioners. PMID: 33586410 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Active Giant Cell Vasculitis Diagnosis with 68Ga PSMA PET/CT Imaging.

xlomafota13 shared this article with you from Inoreader Active Giant Cell Vasculitis Diagnosis with 68Ga PSMA PET/CT Imaging. Via Mol Imaging Radionucl Ther Related Articles Active Giant Cell Vasculitis Diagnosis with 68Ga PSMA PET/CT Imaging. Mol Imaging Radionucl Ther. 2021 Feb 09;30(1):57-59 Authors: Sağer MS, Bilgiç S, Uslu L, Asa S, Sağer G, Sönmezoğlu K Abstract Vasculitis is a multisystem disease characterized by inflammation with infiltration of leukocytes into the blood vessels. Giant cell arteritis (GCA) is the most common form of vasculitis that mostly affects medium- and large-sized arteries. 18Fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) is increasingly used to diagnose inflammation of large arteries in GCA. Galium-68 prostate-specific membrane antigen (PSMA) PET/CT has a vital role in the assessment of patients with prostate cancer for recurrence and metastasis of the disease. Various benign and non-prostate malignant conditions may give rise to increased PSMA uptake. Herein, we demonstrate that PSMA uptake can be seen in GCA. PMID: 33586411 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Unexpected Detection of Abscessualized Lung Carcinoma on Tc-99m-HMPAO-labeled Leukocytes Scintigraphy Misdiagnosed on Chest Computed Tomography.

xlomafota13 shared this article with you from Inoreader Unexpected Detection of Abscessualized Lung Carcinoma on Tc-99m-HMPAO-labeled Leukocytes Scintigraphy Misdiagnosed on Chest Computed Tomography. Via Mol Imaging Radionucl Ther Related Articles Unexpected Detection of Abscessualized Lung Carcinoma on Tc-99m-HMPAO-labeled Leukocytes Scintigraphy Misdiagnosed on Chest Computed Tomography. Mol Imaging Radionucl Ther. 2021 Feb 09;30(1):60-62 Authors: Cosma L, Frantellizzi V, Pontico M, De Vincentis G Abstract Technetium-99m (Tc-99m)-hexamethylpropylene amine oxime (HMPAO)-labeled leukocytes scintigraphy is well established for investigating and diagnosing infections in bone and soft tissue, as well as for the detection of occult infection. A 71-year-old female who was recently diagnosed with bronchopulmonary neuroendocrine tumor of the right lung was referred for an intermittent fever of unknown origin associated with chill at night for the last month. Chest computed tomography (CT) scan showed a thrombotic widespread of the superior vena cava and a solid pathological tissue in the superior segment of the inferior lobe of the right lung with consensual atelectasis. Being a carrier of port-a-cath, an infection of this device was suspected. Therefore, Tc-99m-HMPAO-labeled leukocytes single-photon emission computed tomography (SPECT) was performed, and matching pairs of CT scan and Tc-99m-HMPAO-labeled white blood cell SPECT images were fused. Through this means, it was found that th e area of the radiotracer increased uptake corresponded with the soft tissue density mass detected by CT scan localized at the inferior lobe of the right lung. The hybrid SPECT/CT fused imaging was crucial for diagnosis of the presence of a lung abscess localized in correspondence with the known lung cancer region. PMID: 33586412 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

68Ga PSMA Uptake at Roux-en-Y Eso-jejunostomy Junction Mimicking the Recurrence of Gastric Carcinoma in PET/CT.

xlomafota13 shared this article with you from Inoreader 68Ga PSMA Uptake at Roux-en-Y Eso-jejunostomy Junction Mimicking the Recurrence of Gastric Carcinoma in PET/CT. Via Mol Imaging Radionucl Ther Related Articles 68Ga PSMA Uptake at Roux-en-Y Eso-jejunostomy Junction Mimicking the Recurrence of Gastric Carcinoma in PET/CT. Mol Imaging Radionucl Ther. 2021 Feb 09;30(1):63-66 Authors: Arslan E, Aksoy T, Cin M, Çakır C, Can Trabulus FD, Çermik TF Abstract A 67-year-old male patient had undergone total gastrectomy and Roux-en-Y eso-jejunostomy 3 years ago for the treatment of tubular adenocarcinoma located at the corpus of the stomach. The patient was diagnosed with Gleason score 8 (4+4) metastatic prostate cancer during the follow-up period and received hormone therapy. Owing to his elevated prostate-specific antigen levels (77 ng/mL), his clinician referred him gallium-68 (68Ga) prostate-specific membrane antigen 11 (PSMA) positron emission tomography/computed tomography (PET/CT) for restaging. PET/CT showed multiple 68Ga PSMA receptor-positive skeletal lesions and linear PSMA activity at the eso-jejunostomy junction. He was then referred to undergo 18fluorine-fluorodeoxyglucose (18F-FDG) PET/CT to screen for gastric carcinoma recurrence. PET/CT images demonstrated no 18F-FDG avid lesion. However, endoscopy and biopsy performed with samples from the eso-jejunostomy junction revealed superficial benign squamous epithelial frag ments. PMID: 33586413 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Effect of Sentinel Lymph Node Biopsy and LVI on Merkel Cell Carcinoma Prognosis and Treatment

xlomafota13 shared this article with you from Inoreader Effect of Sentinel Lymph Node Biopsy and LVI on Merkel Cell Carcinoma Prognosis and Treatment Via The Laryngoscope Objective Prognostic factors and optimal treatment approaches for Merkel cell carcinoma (MCC) remain uncertain. This study evaluated the influences of sentinel lymph node (SLN) biopsy and lymphovascular invasion (LVI) on treatment planning and prognosis. Study Design Retrospective cohort study. Methods Stage 1 to 3 MCC patients treated 2005 to 2018. Predictors of nodal radiation were tested using logistic regression. Predictors of recurrence‐free, disease‐specific, and overall survival were tested in Cox proportional hazard models. Results Of 122 patients, 99 were without clinically apparent nodal metastases. Of these, 76 (77%) underwent excision and SLN biopsy; 29% had metastasis in SLNs, including 20% of MCCs 1 cm or less. Primary tumor diameter, site, patient age, gender, and immunosuppressed status were not significantly associated with an involved SLN. Among patients who underwent SLN biopsy, 13 of 21 (62%) MCCs with LVI had cancer in SLNs compared with 14 of 44 (25.5%) without LVI (P = .003). Although local radiation was common, nodal radiation was infrequently employed in SLN negative (pathologic N0) patients (21.8% vs. 76.2% for patients with SLN metastases, P = .0001). Survival of patients with positive SLNs was unfavorable, regardless of completion lymphadenectomy and/or adjuvant radiation. After accounting for tumor (T) and node (N) classification, age, immunosuppression, and primary site, a positive SLN and LVI were independently associated with worse survival (LVI/recurrence‐fr ee survival [RFS]: hazard ratio [HR] 2.3 (1.04–5, P = .04; LVI/disease‐specific survival [DSS]: HR 5.2 (1.8–15, P = .007); N1a vs. pN0/RFS HR 3.6 (1.42–9.3, P = .007); DSS HR5.0 (1.3–19, P = .17). Conclusion SLN biopsy assists in risk stratification and radiation treatment planning in MCC. LVI and disease in SLNs, independently associated with worse survival, constitute markers of high‐risk disease warranting consideration for investigational studies. Level of Evidence III Laryngoscope, 131:E828–E835, 2021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.