Factors Related to Ventilation Tube Extrusion Time in Children and Adults

xlomafota13 shared this article with you from Inoreader Factors Related to Ventilation Tube Extrusion Time in Children and Adults Via ear nose throat Ear Nose Throat J. 2021 Mar 15:145561321999204. doi: 10.1177/0145561321999204. Online ahead of print. ABSTRACT BACKGROUND AND OBJECTIVE: The aim of this study was to investigate the factors affecting extrusion time in both children and adults with ventilation tube (VT) insertion, providing useful information for clinicians for better decision-making, follow strategy, and potentially improve clinical outcomes for these patients. METHODS: Data from patients receiving myr ingotomy with VT insertion from January 1, 2007, to June 30, 2012, were retrospectively collected and analyzed by the end of 2018. Various factors, including age, gender, history of VT insertion, tympanogram, size of VT used, local finding of tympanic membrane, hypertension, diabetes mellitus, hyperlipidemia, and postoperative ear infection, were included and analyzed to examine the effects of these factors on extrusion time. RESULTS: A total of 447 patients were included in this study (Child group-Adult group = 237:210). The overall average extrusion time was 225.85 days. In the subgroup analysis, the average time was 221.3 days and 231.0 days for children and adults, respectively. The results showed that the VT extrusion time was significantly longer in participants without a history of VT insertion and in those where larger sized VTs were inserted in both age-groups. Male gender had an influence on extrusion time in children. In addition, a history of VT insertion and VT si ze were determined to be factors related to extrusion before 12 months in children. CONCLUSION: History of VT insertion and VT size were significantly related to VT extrusion time in both children and adults and defined as factors associated with extrusion before 12 months in children. The findings suggest avoiding VT with a diameter < 1 mm and considering an appropriately larger size in patients with a history of VT insertion to optimize VT retention. PMID:33720800 | DOI:10.1177/0145561321999204 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Germ Line Mutations in the Thyroid Hormone Receptor Alpha Gene Predispose to Cutaneous Tags and Melanocytic Nevi

xlomafota13 shared this article with you from Inoreader Germ Line Mutations in the Thyroid Hormone Receptor Alpha Gene Predispose to Cutaneous Tags and Melanocytic Nevi Via liebertpub1 Thyroid, Ahead of Print. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Retrobulbar hematoma in endoscopic endonasal dacryocystorhinostomy

xlomafota13 shared this article with you from Inoreader Retrobulbar hematoma in endoscopic endonasal dacryocystorhinostomy Via Vestnik otorinolaringologii Vestn Otorinolaringol. 2021;86(1):112-116. doi: 10.17116/otorino202186011112. ABSTRACT Recently, an increase in the number of operations on the lacrimal ducts performed by otorhinolaryngologists has been noted throughout the world. During these operations, intra- and postoperative complications may develop, which require the intervention of an ophthalmologist. A rare complication of endoscopic dacryocystorhinostomy is the development of retrobulbar hemorrhage. This article presents a clinical case of the development of retrobulbar hemorrhage in endoscopic dacryocystorhinostomy. The patient with dacryocystitis underwent endoscopic dacryocystorhinostomy. Preoperative computed tomography revealed a lack of bone tissue in the lacrimal sac fossa. Severe bleeding was noted during the operation. Against the background of tamponade of the formed anastomosis, a growing exophthalmos, conjunctival chemosis, subconjunctival hemorrhage were noted. After removing the tampon, a positive trend was noted. Dexamethasone solution was intraoperatively intravenously administered, in the postoperative period - methylprednisolone solution. According to computed tomography data, exophthalmos persisted on the first day after the operation, hematoma was localized. Visual functions are unchanged. Six months after the operation, the patient had no complaints. According to the computed tomography data, a functioning dacryorhinostomy anastomosis was determined. Often, an interdisciplinary approach to such complications is required, since it can provide full orbital decompression, as well as adequate postoperative management of the patient, which contributes to the most complete ophthalmic rehabilitation. The interaction of otorhinolaryngologists and ophthalmologists in such cases is an indispensable condition for the safety of the operation. PMID:33720663 | DOI:10.17116/otorino202186011112 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The experience in surgical treatment of hearing loss in Van der Hoeve patients

xlomafota13 shared this article with you from Inoreader The experience in surgical treatment of hearing loss in Van der Hoeve patients Via Vestnik otorinolaringologii Vestn Otorinolaringol. 2021;86(1):6-10. doi: 10.17116/otorino2021860116. ABSTRACT Despite the rare incidence of Van der Hoeve syndrome in the population, the problem of treating patients with this type of disease is important for modern science and practical medicine. One of the most difficult tasks in treatment is to improve the quality of hearing. The world scientific community lacks a unified coordinated approach to the methods of auditory rehabilitation of patients with Van der Hoeve syndrome. In recent years, there have been tendencies in the scientific literature to increase the frequency of non-surgical approach due to the low incidence of satisfactory results of surgical treatment. In this regard, we present our experience of complex treatment of patients with Van der Hove syndrome, based on the use of modern surgical technologies and conservative pathogenetically substantiated treatment. PMID:33720643 | DOI:10.17116/otorino2021860116 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

To the question of genetic predisposition to the development of professional sensorineural hearing loss

xlomafota13 shared this article with you from Inoreader To the question of genetic predisposition to the development of professional sensorineural hearing loss Via Vestnik otorinolaringologii Vestn Otorinolaringol. 2021;86(1):15-19. doi: 10.17116/otorino20218601115. ABSTRACT Objective was to study single-nucleotide polymorphisms (SNP) in CAT, NCL, HSPA1L, PCDH15, and PON2 genes and their associations with hearing impairment among the people working among noise-exposed workers of the mashine-building plant (JSC «Krasmash», Krasnoyarsk, Eastern Siberia, Russia). MATERIALS AND METHODS: The 443 employees of Krasmash JSC, who have been working under conditions of increased noise for at least 1 year, were surveyed and examined. A hearing study was performed by speech and tonal audiometry. Tonal audiometry was carried out in accord with according to a standard method in the frequency range 125-8000 Hz. People with chronic hearing impairment, survivors of meningitis and family history of hearing impairment were excluded from the study. The allelic composition of the studied genes was determined in the remaining group of 288 workers (study group). Polymorphisms were detected using bioluminescent method, developed by the authors earlier. The study group comprised 122 people with hearing impairment (experimental group) and 166 people without impairment (control group). RESULTS: The genotyping results of on allelic variants rs494024 (CAT), rs7598759 (NCL), rs2227956 (HSPA1L), rs7095441 (PCDH15) and rs7785846 (PON2) showed that their frequencies in the study group did not differ and were comparable with those for the European population. No statistically significant differences were revealed in the distribution of the genotypes of the studied mutations between the experimental and control groups. Also no statistically significant associations we found between hearing impairment and availability of two or several SNPs, or these SNPs and clinical characteristics of the disease (degree of hearing impairment, tinnitus). In the group of workers with an experience of 5 to 16 years, an association was found for hearing impairment and SNP rs494024, as well as when it is combined with rs7598759. CONCLUSIONS: The associations between SNP rs7598759, rs2227956, and rs7095441 and hearing impairment were not found. In the group of workers with 5-16 year experience, this association was found for SNP rs494024, as well as when it is combined with rs7598759. Discovered associations require further study. PMID:33720645 | DOI:10.17116/otorino20218601115 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Features of the architectonics of the structures of the nasal cavity and choanal zone in children with congenital malformations of the eyes

xlomafota13 shared this article with you from Inoreader Features of the architectonics of the structures of the nasal cavity and choanal zone in children with congenital malformations of the eyes Via Vestnik otorinolaringologii The article provides data on the embryogenesis of the eyeball, nasolacrimal canal and nasal cavity. A frequent combination of congenital choanal atresia and anomalies in the development of the eyes was noted, most likely associated with the temporal and topographic parallelism of the intrauterine development of these anatomical areas. In order to assess the condition of the nasal cavity and choanal region in congenital eye pathology, 43 children with op hthalmological malformations were examined. In 32 (74.4%) children, according to endoscopic examination, changes in the anatomy of the choanal region with a change in its size in the form of incomplete atresia were revealed. The results obtained allow the authors to recommend that all children with congenital ophthalmological malformations be examined and monitored by an otolaryngologist with an endoscopic examination of the nasal cavity and nasopharynx. В статье приведены данные об эмбриогенезе глазного яблока, носослезного канала и полости носа. Отмечено нередкое сочетание врожденной атрезии хоан и аномалий развития глаз, по всей видимости, связанное с временным и топографическим параллелизмом внутриутробного развития данных анатомических областей. С целью оценки состояния полости носа и хоанальной области при врожденной патологии глаз были обследованы 43 ребенка с офтальмологическими пороками развития. У 32 (74,4%) детей по данным эндоскопического обследования выявлены изменения анатомии хоанальной области с изменением ее размеров в виде неполной атрезии. Полученные результаты позволяют авторам рекомендовать всем детям с врожденными офтальмологическими пороками развития осмотр и наблюдение у врача-отоларинголога с проведением эндоскопического исследова ния полости носа и носоглотки. Keywords: Sturge-Weber syndrome; children; congenital choanal atresia; congenital eye defects; endoscopy; stenosis of the nasolacrimal canal. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Transcanal endoscopic middle ear surgery in children with chronic suppurative otitis media

xlomafota13 shared this article with you from Inoreader Transcanal endoscopic middle ear surgery in children with chronic suppurative otitis media Via Vestnik otorinolaringologii Vestn Otorinolaringol. 2021;86(1):25-29. doi: 10.17116/otorino20218601125. ABSTRACT Otomicroscopic surgery remains the gold standard in the surgical treatment of patients with CHS. Endoscopic ear surgery is gaining more and more importance as an adjunct to microsurgery. Recently, thanks to the resolution of the endoscopic technique, endoscopic surgery can be used as an independent method. This article presents the results of endoscopic tympanoplasty, endoscopic removal of the tympanic cholesteatoma, performed on the basis of the otorhinolaryngology department of the Morozov Children's City Clinical Hospital. Research has shown that transcanal endoscopic surgery is an effective alternative to traditional otomicroscopic surgery. Advantage in minimal impact and improved visualization of all quadrants of the tympanic membrane, the anterior tympanomeatal angle of the NSP, and structures of the middle ear. PMID:33720647 | DOI:10.17116/otorino20218601125 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.