Myxoma of the mandibular condyle: Report of a rare case and review of the literature

Publication date: Available online 9 March 2018
Source:Oral Oncology
Author(s): Everaldo Pinheiro de Andrade Lima, Flávia Maria de Moraes Ramos-Perez, Rômulo Oliveira de Hollanda Valente, Jorge Esquiche León, Paulo Rogério Ferreti Bonan, Danyel Elias da Cruz Perez
This report describes an extremely rare case of myxoma of the mandibular condyle. The tumor occurred in the left mandibular condyle of a 42-year-old woman, which was identified in a routine radiographic examination. The clinico-radiographic and histopathological features, and histogenesis of the lesion are discussed. A review of the literature and differential diagnosis of radiolucent condylar lesions are also presented.



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Treatment and frequency of follow-up of BCC patients in the Netherlands

Abstract

The incidence of Basal Cell Carcinoma (BCC) rises by 5% per decade in the Netherlands (1), representing an important burden on the health care system and dermatologists' workload (2,3). There is no evidence that intensive follow-up results in better outcomes (burden of disease, cosmetic results) in patients with low risk BCCs (4–6). According to the Dutch BCC guideline, follow-up after treatment is not indicated for patients with a low risk BCC (7), but patients may come for follow-up more frequently for various reasons (4,7,8). Considering the enormous amount of patients, extra follow-up visits represent a substantial workload and healthcare costs. Therefore, we studied follow-up of 482 BCC patients, diagnosed in 2010 from general hospitals (N=291 – random sample from a population-based cancer registry) and academic hospitals (N=191), who had a total of 578 BCC diagnosed in 2010. Information on medical history, tumor characteristics and the treatment and follow-up of all diagnosed BCCs was retrieved from the patient files until April 2015.

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Immunohistochemical identification of nail matrix melanocytes

Abstract

Background

No previous studies have been conducted to determine the normal number of nail matrix melanocytes in Latin American individuals. The objective of this work was to determine the number of melanocytes per linear millimeter present in the nail matrix and the nail bed in samples obtained from Colombian individuals.

Methods

Twenty-six unilateral biopsies were taken from 19 cadavers subjected to clinical and medico-legal autopsies. These biopsy samples were processed with conventional histotechnology and immunohistochemistry (IHC) with anti-HMB-45 and anti-MiTF. Three sets of photographs (HE, HMB-45 and MiTF) were taken of each biopsy sample and independently assessed by three pathologists. Each observer counted the number of melanocytes present in 1 linear mm of the nail matrix or bed.

Results

We found an average of 4.6 melanocytes x linear mm with H & E staining, 9.8 with HMB-45 and 12.4 with MiTF.

Conclusions

The use of IHC significantly increases and facilitates the identification of melanocytes in unilateral biopsies. Our IHC counts exceed the averages found in the literature. This finding warrants new studies to verify whether the Colombian population presents higher numbers of melanocytes in the nail matrix than other populations or whether the observed increase is a result of the use of MiTF.

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A case of subepidermal autoimmune bullous disease with autoantibodies against 200-kDa and 290-kDa antigens

Abstract

Epidermolysis bullosa acquisita (EBA) and anti-p200 pemphigoid are uncommon subepidermal autoimmune bullous diseases caused by autoantibodies against the 200-kDa protein and 290-kDa type VII collagen, respectively. Here we describe a patient with autoantibodies against both 200-kDa and 290-kDa antigens.A 63-year-old-man had itchy tense blisters and edematous erythemas scattered on his trunk, buttocks, extremities and soles (Fig. 1a). There were no ocular or mucosal lesions. Psoriatic skin lesions were not observed. There was no personal or family history of serious diseases.

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Patch Testing in Gastrointestinal Diseases – A Systematic Review of the Patch Test (PT) and Atopy Patch Test (APT)

Abstract

Food allergy is common and the prevalence is increasing. The pathogenesis of food allergy has been extensively reviewed. Immunologic and clinical tolerance to food requires production of regulatory T cells that are food-antigen specific. Loss of tolerance to food can lead to IgE-mediated reactions and non-IgE-mediated reactions.

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Contact hypersensitivity in rosacea – a report on 143 cases

Abstract

Rosacea is a chronic skin disease characterized by inflammatory processes affecting mainly the center of the face. The pathophysiology is complex, environmental factors seem to play an important role in the exacerbation and worsening of the lesions. The barrier-dysfunction theory in atopic dermatitis has been well described in the literature.

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Reply to: Kubiak K. And al. Endosymbiosis and its significance in dermatology

Abstract

We would like to begin by congratulating Kubiak K et al on their work[1], which has the potential to contribute to review the question of endosymbiosis and its significance.We would like to add some new data, notes and comments. Some data regarding viral endosymbiosis other than those discussed by the authors, showed the transmission of a Gemycircularvirus - Sclerotinia sclerotiorum hypovirulence-associated DNA1- like virus (SsHADV-1–LV)- via insect vectors - Lycoriella ingenua.

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