TERT, HRAS, and EIF1AX Mutations in a Patient with Follicular Adenoma

Thyroid, Ahead of Print.


https://ift.tt/2GvAHyU

Innate effector cells in angiogenesis and lymphangiogenesis

Gilda Varricchi | Stefania Loffredo | Maria Rosaria Galdiero | Giancarlo Marone | Leonardo Cristinziano | Francescopaolo Granata | Gianni Marone

https://ift.tt/2LcRJ8E

Strategies for a multi-stage neutralizing antibody-based HIV vaccine

Raiees Andrabi | Jinal N Bhiman | Dennis R Burton

https://ift.tt/2KC8Rnr

Lymphatics in the liver

Masatake Tanaka | Yasuko Iwakiri

https://ift.tt/2KATdIH

Basal Cell Carcinoma, PART II: Contemporary Approaches to Diagnosis, Treatment, and Prevention

As the most common human cancer worldwide and continuing to increase in incidence, basal cell carcinoma is associated with significant morbidity and cost. Continued advances in research have refined both our insight and approach to this seemingly ubiquitous disease. This 2-part continuing medical education article will provide a comprehensive and contemporary review of basal cell carcinoma. Part II of this series will present both standard of care and newly developed approaches to diagnosis, treatment, and prevention of this disease.

https://ift.tt/2wU5Mgj

Basal Cell Carcinoma: Part 1

As the most common human cancer worldwide and continuing to increase in incidence, basal cell carcinoma is associated with significant morbidity and cost. Continued advances in research have refined both our insight and approach to this seemingly ubiquitous disease. This 2-part continuing medical education article will provide a comprehensive and contemporary review of basal cell carcinoma. Part I of this series will describe our current understanding of this disease in regards to epidemiology, cost, clinical and histopathologic presentations, carcinogenesis, natural history, and disease associations.

https://ift.tt/2rRpkgj

Ability of blue laser imaging with magnifying endoscopy for the diagnosis of gastric intestinal metaplasia

Abstract

We aimed to determine the utility of blue laser imaging (BLI) with magnifying endoscopy (BLI-ME) for the prediction and diagnosis of gastric intestinal metaplasia (GIM). Participants, aged between 40 and 75 years, undergoing gastroscopy from January to April 2017 were included in this study. The ability of BLI-ME and white light endoscopy (WLE) to detect GIM was assessed by comparing the endoscopic findings with the histological findings. The correlation between the grades of light blue crest (LBC) appearance and histology grade of GIM was calculated. We included 100 participants in this study. GIM was diagnosed in 27 participants; 20 participants were detected by both BLI and WLE, four by BLI only, and three exclusively by random biopsies. The values of sensitivity, specificity, positive predictive values, and negative predictive values for detecting GIM were 34.9, 38.9, 25.4, and 57.1%, respectively, for WLE and 88.9, 96.7, 94.1, and 93.3%, respectively, for BLI-ME. The diagnostic accuracy for GIM was 43% for WLE and 94.0% for BLI-ME. A good correlation between the grades of LBC and the grades of GIM on histology was observed (P < 0.01). BLI-ME achieved a good diagnostic efficiency for detection of GIM. LBC seen on BLI-ME is a typical indicator of GIM.

https://ift.tt/2rWx4Nc