Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Παρασκευή 6 Ιουλίου 2018

The role of the otolaryngologist in the evaluation and management of headaches

Publication date: Available online 7 July 2018

Source: American Journal of Otolaryngology

Author(s): Shirley Hu, Samuel Helman, Peter Filip, Jonathan Cabin, Patrick Colley

Abstract
Background

Headaches are commonly evaluated in otolaryngology and often represent a diagnostic dilemma. This review addresses rhinogenic headache as well as trigeminal neuralgia and migraine, both of which can masquerade as sinus headache and whose management increasingly involves otolaryngology intervention. Discussion considers diagnostic criteria and novel therapies and derives an algorithm for clinical decision-making.

Data sources

OVID MEDLINE, Cochrane Library, and Google Scholar databases.

Methods

A literature search was performed to identify relevant articles published in the past 10 years addressing the diagnosis and management of rhinogenic headache, trigeminal neuralgia and/or migraine.

Findings

Rhinogenic headache: Identification of the specific cause must be achieved before treatment. No studies have mentioned the effect of certain therapies on the amelioration of headache. New techniques of balloon dilation for sinusitis are controversial, and their use remains contingent on surgeon preference. Removal of mucosal contact points has been shown to benefit quality of life in patients with contact point headache. Trigeminal neuralgia: Microvascular decompression is considered the gold standard for treatment, but percutaneous therapies can be effective for achieving pain control. Migraine: Patients who report amelioration of symptoms after targeted botulinum toxin injection may benefit from definitive decompression or nerve avulsion. Patients with mucosal contact points may have less favorable outcomes with migraine surgery if they are not simultaneously addressed.

Conclusions

A comprehensive understanding of the diagnostic workup and therapeutic options available for common headache etiologies is key to the management of a patient presenting with headache attributed to a rhinogenic cause.



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Cadaveric dissection in oral and maxillofacial surgery: is it time for a new approach?

Publication date: Available online 7 July 2018

Source: British Journal of Oral and Maxillofacial Surgery

Author(s): A. Kanatas, D.A. Mitchell



https://ift.tt/2MVywbL

Preconceptional allergen immunization can induce offspring IL-17 secreting B cells (B17): do they share similarities with regulatory B10 cells?

Publication date: Available online 7 July 2018

Source: Allergologia et Immunopathologia

Author(s): Aline Aparecida de Lima Lira, Marília Garcia de-Oliveira, Amanda Harumi Sabô Inoue, Giovanna Rossi Beltrame, Alberto José da Silva Duarte, Jefferson Russo Victor

Abstract
Background

IL-17-producing B cells can be identified in both mice and human and were named B17 cells. The role of B17 cells still needs to be elucidated and its inflammatory or regulatory functions remain controversial.

Objective

We evaluate the effect of maternal immunization with OVA on offspring B cells that produces IL-17 and can show a regulatory potential by IL-10 production.

Methods

C57BL/6 WT, IL-10−/− or CD28−/− female mice were immunized or not with OVA in Alum, and immunized females were boosted after 10 and 20 days. Immunized and non-immunized females were mated, and pups from both groups were evaluated at 3 or 20 days old (d.o.). Some offspring from the aforementioned two groups were immunized with OVA at 3 d.o., boosted after 10 days and evaluated at 20 d.o.

Results

Maternal immunization with OVA induced offspring B cells to produce IL-17 at higher intensity compared to the control group of offspring at 3 d.o. This effect was maintained until 20 d.o. and even after neonatal immunization with OVA. The co-production of IL-10 on offspring IL-17 + B cells is up-regulated in response to maternal immunization with OVA. Maternal immunization with OVA on IL-10−/− mice reveals reduced percentage and mean of fluorescence intensity of IL-17 on B cells of offspring.

Conclusion

Preconception OVA immunization can induce offspring B cells that produce IL-17 at higher intensity and co-produce mainly IL-10. This could be the reason why B17 cells had been described in the literature with controversial roles upon their regulatory function.



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Salivary IgA Deficiency in a Patient with Cystic Fibrosis (genotype M470V/V520F)

Publication date: Available online 7 July 2018

Source: Annals of Allergy, Asthma & Immunology

Author(s): Jessica Oh, David P McGarry, Nancy Joseph, Brian Peppers, Robert Hostoffer



https://ift.tt/2MYnra2

Pediatric Ambulatory Continuous Peripheral Nerve Blocks

Publication date: Available online 7 July 2018

Source: Anesthesiology Clinics

Author(s): Sible Antony, Harshad Gurnaney, Arjunan Ganesh



https://ift.tt/2lXVAuR

Regional Anesthesia and Analgesia for Acute Trauma Patients

Publication date: Available online 7 July 2018

Source: Anesthesiology Clinics

Author(s): Ian R. Slade, Ron E. Samet



https://ift.tt/2ub5j4U

What Can Regional Anesthesiology and Acute Pain Medicine Learn from “Big Data”?

Publication date: Available online 7 July 2018

Source: Anesthesiology Clinics

Author(s): Nabil M. Elkassabany, Stavros G. Memtsoudis, Edward R. Mariano



https://ift.tt/2lXQZZC