Aluminum phosphide is a very common suicide agent in developing countries like Nepal. Due to the unavailability of a specific antidote, mortality is very high because the phosphine molecule that is formed lead...
https://ift.tt/2OW15uW
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Σάββατο 27 Οκτωβρίου 2018
Extracorporeal membrane oxygenation in aluminum phosphide poisoning in Nepal: a case report
Management of the Neck for Non-melanoma Skin Cancer
Abstract
Purpose of Review
To summarize the current management of the neck lymph node basin for head and neck non-melanoma skin cancers.
Recent Findings
Over the last 5 years, there have been updates to staging for cSCC and MCC. T classification of the AJCC staging system has been changed to match the UICC staging system. MCC staging has been updated based on data from the National Cancer Data Base. Sentinel lymph node biopsy, while established in MCC, is playing a growing role in the management of high-risk N0 cSCC.
Summary
The optimal management of N0 neck varies by metastatic potential. In low-risk malignancy, no workup is necessary. In cSCC, risk stratification is necessary. High-risk tumors with N0 necks should undergo preoperative imaging with CT and targeted FNA of suspicious lymph nodes. If radiologically negative, a SLNB should be considered. Selective neck dissection should be performed for N+ disease and positive SLNB. Elective neck dissection is not routinely recommended and should be reserved for positive parotid nodal disease. Merkel cell carcinoma has high rates of nodal metastases and requires preoperative imaging with targeted FNA of suspected metastases. SLNB should be performed for N0 disease to guide prognostication and further treatment. Management of negative SLN is controversial, and most can be observed while radiation may be considered for high-risk patients. Positive SLN requires completion neck dissection and radiation.
https://ift.tt/2PuEjd6
Can asthma be well controlled with NAEPP guideline care in morbidly obese children? The Breathmobile
Obesity is thought to be associated with poor asthma control, increased health resource utilization, and reduced responsiveness to inhaled corticosteroids.
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Dear Dr. Dermatoethicist: Exam of the Future or Exam of Future Cheating? Ethical Issues Surrounding the American Board of Dermatology’s New Certification Examination
https://ift.tt/2OTMoss
Present and future perspective of photodynamic therapy for cutaneous squamous cell carcinoma
Photodynamic therapy may benefit patients with cutaneous squamous cell carcinoma who are not eligible for surgery. Photodynamic therapy can be modified to provide better effect by use of microneedles or laser, by use of intralesional injection of photosensitizers instead of topical application, by use of nanoparticles or by use of adjuncts.
https://ift.tt/2Rh30ac
Non-cultured epidermal suspension grafting using suction blisters as donor tissue for vitiligo
https://ift.tt/2OSCUO5