Surgical rehabilitation of swallowing with polydimethylsiloxane injections after open partial horizontal laryngectomy: Long‐term functional results and quality of life

xlomafota13 shared this article with you from Inoreader Surgical rehabilitation of swallowing with polydimethylsiloxane injections after open partial horizontal laryngectomy: Long‐term functional results and quality of life Via Head & Neck Abstract Background Swallowing disorders are common problems after partial laryngectomy. The aim of this study is to illustrate the long‐term functional results of rehabilitation of swallowing by polydimethylsiloxane (PDMS) injection. Methods Twenty‐eight patients with dysphagia after partial laryngectomy who underwent injection of PDMS for rehabilitation of swallowing were included in the study. Impairment of swallowing and quality of life (QoL) were investigated with questionnaires: M. D. Anderson Dysphagia Inventory (MDADI) and Performance Status Scale for Head and Neck Cancer (PSS‐HNC). Functional results at fiberoptic endoscopic evaluation of swallowing (FEES) were analyzed using a modified penetration‐aspiration scale. Results Mean follow‐up was 8.5 years. Twenty‐six patients showed an improvement at questionnaires (p < 0.001). Median improvement was 6 (p < 0.001) in the modified penetration‐aspiration scale. Total laryngectomy was required in one patient. Conclusions PDMS injection is a good option for rehabilitation of swallowing in case of dysphagia after partial laryngectomy. It improves QoL and the results persist after a long follow‐up period. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Muscle invasion in oropharyngeal carcinoma undergoing transoral robotic surgery

xlomafota13 shared this article with you from Inoreader Muscle invasion in oropharyngeal carcinoma undergoing transoral robotic surgery Via Head & Neck Abstract Backgrounds Pathologic features of oropharyngeal squamous cell carcinoma (OPSCC) treated with trans‐oral robotic surgery predict prognosis and adjuvant therapy. We hypothesized that pathologic muscle invasion (pMI) is associated with poor pathological markers. Methods Retrospective review of surgically treated OPSCC to identify pMI and its association with poor pathologic markers. Results pMI was present in 12/37 patients, and compared to non‐pMI, was associated with higher rates of lymphovascular invasion (75% vs. 36%, p = 0.03), perineural invasion (16.7% vs. 0%, p = 0.04), extranodal extension (66.7% vs. 20%, p < 0.01), and tumor stage (8.3% vs. 48% pT1, 75% vs. 52% pT2 and 16.7% vs. 0% pT3). pMI was associated with having a positive margin on main specimen (41.7% vs. 12%, p = 0.04) but not after considering additional margins. Conclusions Muscle invasion was associated with higher pathologic tumor staging, poor pathologic factors, and higher rates of positive margin on main specimen. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Increased rate of recurrence and high rate of salvage in patients with human papillomavirus–associated oropharyngeal squamous cell carcinoma with adverse features treated with primary surgery without recommended adjuvant therapy

xlomafota13 shared this article with you from Inoreader Increased rate of recurrence and high rate of salvage in patients with human papillomavirus–associated oropharyngeal squamous cell carcinoma with adverse features treated with primary surgery without recommended adjuvant therapy Via Head & Neck Abstract Background Some patients with human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma (OPSCC) do not receive guideline‐recommended postoperative radiation therapy (PORT) following primary transoral robotic surgery (TORS). Methods Three‐hundred and sixty‐four patients with treatment‐naïve, HPV‐associated OPSCC were recommended to receive PORT based on clinicopathological features following TORS. Patients were stratified based on if they received PORT. Oncologic outcomes were compared. Results The 3‐year locoregional failure (LRF) was 32% in patients who did not receive PORT and 4% in patients who received PORT (P < .001). Despite increased LRF, avoiding PORT was not associated with increased 3‐year distant metastasis rates (8% vs 4%, P = .56) or worse 3‐year survival (95% vs 98%, P = .34). Recurrences in the surgery alone cohort varied between local and regional sites and were often successfully salvaged. Conclusions Patients with HPV‐associated OPSCC who do not receive indicated PORT have an increased risk of LRF but similar survival due to high salvage rates. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Response Evaluation Criteria in Solid Tumors (RECIST) and PET Response Criteria in Solid Tumors (PERCIST) for response evaluation of the neck after chemoradiotherapy in head and neck squamous cell carcinoma

xlomafota13 shared this article with you from Inoreader Response Evaluation Criteria in Solid Tumors (RECIST) and PET Response Criteria in Solid Tumors (PERCIST) for response evaluation of the neck after chemoradiotherapy in head and neck squamous cell carcinoma Via Head & Neck Abstract Background An optimal approach to imaging assessment of neck after chemoradiotherapy must be established to avoid unnecessary neck dissection. Methods We retrospectively examined 101 patients and compared between Response evaluation criteria in solid tumors (RECIST), PET response criteria in solid tumors (PERCIST), and positron emission tomography/computed tomography (PET/CT) qualitative assessment. Results PERCIST was superior to RECIST in positive predictive value (PPV; 47% vs. 36%), with equivalent negative predictive value (NPV; 78%). Only 3 of 15 patients with incomplete responses on either RECIST or PERCIST alone had regional treatment failure, and the combination of RECIST and PERCIST improved PPV (55%) without reducing NPV. This combination yielded the highest hazard ratio of regional treatment failure. The combination of RECIST and PET/CT qualitative assessment also improved PPV (50%). In human papillomavirus (HPV)–related oropharyngeal cancer, NPV was 100% across the imaging assessments, while PPV was poor (14%–33%). Conclusions Combining RECIST and PERCIST might optimize decision making in neck management after chemoradiotherapy. HPV status would affect the accuracy of response evaluation. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Benign connective and soft‐tissue neoplasms of the oral and maxillofacial region: Cross‐sectional study of 1066 histopathological specimens

xlomafota13 shared this article with you from Inoreader Benign connective and soft‐tissue neoplasms of the oral and maxillofacial region: Cross‐sectional study of 1066 histopathological specimens Via Head & Neck Abstract Background Benign connective and soft‐tissue neoplasms (CSTNs) are unusual in the head and neck region. The aim of the present study was to evaluate the demographic and clinicopathological features of these neoplasms. Methods A cross‐sectional study was conducted of cases diagnosed as benign CSTNs, with data collected from biopsy records. The chi‐square test was used. A p‐value <0.05 was considered indicative of statistical significance. Results Among the 38 119 specimens, 1066 (2.79%) were benign CSTNs: 369 fibroblastic/myofibroblastic, 250 adipocytic, 179 vascular, 130 neural, 94 osseous/cartilaginous, 19 muscular, and two fibrohistiocytic. Most patients were female (62.8%) and white‐skinned (45.8%). Mean age was 42 years. The tongue (25.2%) was the most affected site for extraosseous neoplasms. Conclusion This study had the largest sample of benign oral and maxillofacial CSTNs. Although these tumors have similar clinical features, the characterization and differentiation detailed here may help clinicians with regards to the correct diagnosis. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Speech and language characteristics in Smith–Magenis syndrome: Case report

xlomafota13 shared this article with you from Inoreader Message: Smith-Magenis syndrome (SMS) is a developmental disorder that affects many parts of the body. The major features of this condition include mild to moderate intellectual disability , delayed speech and language skills, distinctive facial features, sleep disturbances, and behavioral problems. Smith-Magenis syndrome | Genetic and Rare Diseases ... Speech and language characteristics in Smith–Magenis syndrome: Case report Via Logopedia, Foniatría y Audiología Publication date: Available online 24 March 2021 Source: Revista de Logopedia, Foniatría y Audiología Author(s): Elena Garayzábal Heinze, Irene Hidalgo de la Guía, Kriscia Gobi Rosa, Célia Maria Giacheti, Natalia Freitas Rossi View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Incorporating Virtual Reality to Improve Otolaryngology Resident Wellness: One Institution's Experience

xlomafota13 shared this article with you from Inoreader Incorporating Virtual Reality to Improve Otolaryngology Resident Wellness: One Institution's Experience Via The Laryngoscope Objective Burnout is defined as work‐related emotional exhaustion, depersonalization, and decreased sense of accomplishment. Virtual reality (VR) has emerged as an effective treatment modality for various conditions related to anxiety, however, few studies have assessed its role for stress management in residents. We hypothesize that VR‐based mindfulness meditation can reduce resident burnout in real‐world settings. Study Design Prospective randomized crossover trial. Methods Resident participants completed the validated Maslach Burnout Inventory (MBI). One group used a VR‐based meditation app; the second group received no intervention. After a 2‐month rotation, all subjects completed an MBI and crossed over to the other arm. Wilcoxon rank‐sum tests were used to compare MBI scores before and after intervention, and to compare results by gender and postgraduate year. Mann‐Whitney U tests were used to assess qualitative differences between participants. Results Eighteen residents completed the study. Five participants were female and 13 were male. Weekly use of VR‐guided meditation and paced breathing was associated with a significant decrease in emotional exhaustion (P = .009), and on subgroup analysis, male gender specifically was associated with a decrease in emotional exhaustion (P = .027). In the post‐intervention survey, 42.9% subjects reported that VR encouraged them to employ paced breathing techniques, 71.4% reported that they would use the technology if regularly available, and 21.4% reported they would use paced breathing in the future. Conclusion VR‐based therapy may serve as a successful tool in stress management and reduce the rate of burnout among otolaryngology residents. Level of Evidence N/A Laryngoscope, 2021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.