New ENT Abstracts

Thyroid tumor ratio: Improving the assessment of the impact of size in pediatric thyroid cancer
3d
by
Connie Paik, Beth Osterbauer, Grace Sahyouni, Soyun Park, Gabriel Gomez, Daniel Kwon, Juliana Austin
via
Head & Neck
Abstract
Background
The impact of thyroid nodule size is less useful in children who have smaller thyroid volumes than in adults. We investigate using a novel thyroid tumor ratio measurement in children with thyroid cancer.

Methods
Patient and pathologic characteristics were investigated via Student's t-test in a univariate analysis for any correlation with the log-transformed tumor ratio, followed by a multivariate linear regression.

Results
Of 75 patients with malignancy and tumor ratio information, mean ratio decreased with increasing age (p = 0.04). Out of several clinical factors, patients with lymph node metastases and those treated with postoperative radioactive iodine had significantly higher mean tumor ratios on multivariate analysis (p = 0.04 for both factors).

Conclusions
Our study is the first to describe thyroid tumor volume in pediatric thyroid cancer and shows that increased tumor ratio was associated with indicators of more advanced disease such as lymph node metastases and use of radioactive iodine.

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Efficacy and safety of preoperative embolization in carotid body tumor treatment: A propensity score matching retrospective cohort study
3d
by
Zhaoyu Wu, Peng Qiu, Hongji Pu, Kaichuang Ye, Guang Liu, Weimin Li, Xiaobing Liu, Minyi Yin, Mier Jiang, Jinbao Qin, Xinwu Lu, Zhen Zhao
via
Head & Neck
Abstract
Background
To assess the efficacy and safety of preoperative embolization (PE) in patients with carotid body tumor (CBTs).

Methods
In a single-center retrospective cohort study, 127 patients underwent surgical resection of CBTs from January 2003 to December 2019. One-to-one propensity score matching was conducted between patients with or without PE.

Results
Thirty-two (25.2%) patients received PE. After propensity score matching, no statistically significant differences were found in the baseline characteristics of 28 patients in each group. Compared with NPE group, operative time and estimated blood loss (EBL) were significantly reduced in the PE group. The incidence of stroke, perioperative complications, intraoperative blood transfusion, vascular reconstruction, hospital stay, tumor recurrence, and all-cause mortality were not different between the PE and NPE group.

Conclusions
Preoperative embolization was efficient and safe with a reduction of intraoperative blood loss and operative time during CBT resection.

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Post‐acute health care needs of people with head and neck cancer: Mapping health care services, experiences, and the impact of rurality
3d
by
Jasmine Foley, Clare L. Burns, Elizabeth C. Ward, Rebecca L. Nund, Laurelie R. Wishart, Lizbeth M. Kenny, Maurice Stevens
via
Head & Neck
Abstract
Background
People with head and neck cancer (HNC) have complex health care needs; however, limited evidence exists regarding the nature or patterns of service access and use. This study explored the post-discharge health care needs and experiences of individuals with HNC from metropolitan and rural areas.

Methods
Health care appointments and services accessed by people with HNC were collated for 6-month post-treatment. Data analysis of the whole cohort examined patterns of access while journey mapping integrated participants' experiences of recovery.

Results
The 6-month service access journey was mapped for 11 people. Rural participants attended a significantly greater number of appointments (p = 0.012), higher canceled/missed appointments (p = 0.013), and saw more professionals (p = 0.007). Rural participants reported higher stress and burden due to service access barriers and unmet needs.

Conclusions
Multiple challenges and inequities exist for rural people with HNC. Findings inform opportunities to enhance the post-treatment recovery of people with HNC in rural areas.

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,

Telephone consultation 11855 int 1193,

Effects and influencing factors of vestibular rehabilitation in 171 cases

xlomafota13 shared this article with you from Inoreader Effects and influencing factors of vestibular rehabilitation in 171 cases Via Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Mar 7;57(3):263-269. doi: 10.3760/cma.j.cn115330-20210601-00321. ABSTRACT Objective: To explore the effect of vestibular rehabilitation and to identify factors that can affect rehabilitation outcomes. Methods: From December 2018 to October 2020, patients who underwent vestibular rehabilitation in the Eye, Ear, Nose and Throat Hospital of Fudan University were prospectively followed up. A battery of vestibular function examinations and psychological status evaluations were applied before and after rehabilitation initiation. The main outcomes were vertigo/dizziness and unsteadiness, measured by visual analogue scale (VAS); Secondary outcomes were daily activities and participation, assessed by vestibular activities and participation measure (VAP). Paired t-test was used to compare the effects before and after rehabilitation. Binary logistic regressions were applied to anal yze the influencing factors of rehabilitation outcomes. Results: A total sample of 171 patients was followed up regularly with a median time of 11 months. Of the 171 patients evaluated, 72 were males and 99 were females; age ranged from 10 to 89 years old with a median age of 55 years old. At 6-month follow-up, the difference of VAS score of vertigo/dizziness and unsteadiness pre-post rehabilitation was 1.79±1.80 and 1.56±1.76, respectively; The difference of activity and participation domain of VAP score was 2.51±13 and 1.27±3.75, respectively. All differences pre-post rehabilitation exhibited statistically significant with P values<0.01. Regression analysis demonstrated that the length of symptom onset was a significant predictor of poor balance recovery (OR=6.52; 95%CI:2.10, 20.27). Visual dependence (OR=5.44; 95%CI: 1.38, 21.47) and suspectable anxiety (OR=6.45; 95%CI: 1.49, 28.30) were identified as risk factors for poor recovery of vertigo/dizziness. Conclusions: Vestibular rehabilitation effectively reduces dizziness, promotes balance, and improves the function of daily activities. Time from the onset, visual dependence and suspectable anxiety are the main factors hindering a desirable rehabilitation outcome. PMID:35325936 | DOI:10.3760/cma.j.cn115330-20210601-00321 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Correlation analysis of smell and taste loss with COVID-19 outbreak trend based on big data of internet

xlomafota13 shared this article with you from Inoreader Correlation analysis of smell and taste loss with COVID-19 outbreak trend based on big data of internet Via Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Mar 7;57(3):282-288. doi: 10.3760/cma.j.cn115330-20210808-00536. ABSTRACT Objective: To analyze the correlation between loss of smell/taste and the number of real confirmed cases of coronavirus disease 2019 (COVID-19) worldwide based on Google Trends data, and to explore the guiding role of smell/taste loss for the COVID-19 prevention and control. Methods: "Loss of smell" and "loss of taste" related keywords were searched in the Google Trends platform, the data were obtained from Jan. 1 2019 to Jul. 11 2021. The daily and newly confirmed COVID-19 case number were collected from World Health Organization (WHO) since Dec. 30 2019. All data were statistically analyzed by SPSS 23.0 software. The correlation was finally tested by Spearman correlation analysis. Results: A total of data from 80 weeks were collected. The retrospective analysis was performed on the new tre nd of COVID-19 confirmed cases in a total of 186 292 441 cases worldwide. Since the epidemic of COVID-19 was recorded on the WHO website, the relative searches related to loss of smell/taste in the Google Trends platform had been increasing globally. The global relative search volumes of "loss of smell" and "loss of taste" on Google Trends was 10.23±2.58 and 16.33±2.47 before the record of epidemic while 80.25±39.81 and 80.45±40.04 after (t value was 8.67, 14.43, respectively, both P<0.001). In the United States and India, the relative searches for "loss of smell" and "loss of taste" after the record of epidemic were also much higher than before (all P<0.001). The correlation coefficients between the trend of weekly new COVID-19 cases and the Google Trends of "loss of smell" in the global, United States, and India was 0.53, 0.76, and 0.82 respectively (all P<0.001), the correlation coefficients with Google Trends of "loss of taste" was 0.54, 0.78, and 0.82 respectively (all P<0.001). The lowest and highest point of loss of smell/taste search curves of Google Trends in different periods appeared 7 to 14 days earlier than that of the weekly newly COVID-19 confirmed cases curves, respectively. Conclusions: There is a significant positive correlation between the number of newly confirmed cases of COVID-19 worldwide and the amount of keywords, such as "loss of smell" and "loss of taste", retrieved in Google Trends. The trend of big data based on Google Trends might predict the outbreak trend of COVID-19 in advance. PMID:35325939 | DOI:10.3760/cma.j.cn115330-20210808-00536 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Human papillomavirus-related multiphenotypic sinonasal carcinoma: A report of two patients and review of the literature

xlomafota13 shared this article with you from Inoreader Human papillomavirus-related multiphenotypic sinonasal carcinoma: A report of two patients and review of the literature Via Auris Nasus Larynx Publication date: Available online 24 March 2022 Source: Auris Nasus Larynx Author(s): Satoru Miyamaru, Tetsuji Sanuki, Yusuke Miyamoto, Kohei Nishimoto, Masako Masuda, Yumi Honda, Yoshiki Mikami, Yorihisa Orita View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Potential effects of lowering the threshold of statistical significance in the field of chronic rhinosinusitis - A meta-research on published randomized controlled trials over last decade

xlomafota13 shared this article with you from Inoreader Potential effects of lowering the threshold of statistical significance in the field of chronic rhinosinusitis - A meta-research on published randomized controlled trials over last decade Via Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial Braz J Otorhinolaryngol. 2021 Dec 4:S1808-8694(21)00196-8. doi: 10.1016/j.bjorl.2021.11.004. Online ahead of print. ABSTRACT OBJECTIVE: To evaluate the impact of change in p-value threshold from 0.05 to 0.005, on published Randomized Controlled Trials (RCTs) over the last ten years in the field of chronic rhinosinusitis. METHODS: A search of the PubMed database from 1st January 2011 to 31st December 2020 was conducted to include all RCTs that used p-value to determine the effects of an intervention. Data extracted included p-values, type of intervention, publishing journal with indexing, registration, funding, and multi- or single center status. The proportion of primary endpoints having p < 0.005 was determined first, followed by those with p > 0.005 but <0.05. Logistic regression analysis was used to determine if any trial characteristic was associated with reporting of significant p-values. RESULTS: In total, 16 8 primary endpoints were identified from 123 RCTs. On analysis, 80 had a p-value <0.05, i.e., statistically significant on conventional parameter. Out of these, 53.75% had a p-value <0.005, which would retain significance under the proposed threshold, and the remaining 46.25% to be reclassified as "suggestive". None of the trial characteristics were contributing to reporting of conventional or proposed p-values on logistic regression analysis. CONCLUSION: Lowering the p-value threshold would render 46.25% of a decade of published RCTs results (in the field of CRS) to be reclassified as merely "suggestive" and not significant. Trial characteristics were not found contributing to reporting of p-value <0.005 or even <0.05. LEVEL OF EVIDENCE: II. PMID:35331655 | DOI:10.1016/j.bjorl.2021.11.004 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The Auditory Processing Domains Questionnaire (APDQ): Brazilian-Portuguese version

xlomafota13 shared this article with you from Inoreader The Auditory Processing Domains Questionnaire (APDQ): Brazilian-Portuguese version Via Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial Braz J Otorhinolaryngol. 2022 Jan 4:S1808-8694(21)00213-5. doi: 10.1016/j.bjorl.2021.12.001. Online ahead of print. ABSTRACT OBJECTIVE: The present study aimed to determine the fidelity, reliability, and internal validity of the APDQ when translated from English to Brazilian-Portuguese language. METHODS: The first phase included the APDQ translation into Brazilian-Portuguese including forward translation, translation assessment and back-translation in a group of 10 students. The second phase involved establishing the internal consistency and reliability of the APDQ Brazilian-Portuguese version. Data was collected from 66 students without any risk factor for auditory processing disorder. Subjects were divided into a younger group (7-10 yrs) and an older group (11-17 yrs). RESULTS: All items showed appropriate quality in terms of translation. In determining internal consistency, Cronbach's alpha in subscales of auditory proce ssing, attention and language was found to be 0.93, 0.85 and 0.74, respectively. Intraclass Correlation Coefficient for total score was 0.95, ensuring a strong test-retest reliability. CONCLUSION: The Brazilian-Portuguese version of the APDQ has favorable translation quality, internal validity and reliability. It is now ready for continued study as a differential screening tool for 7- to 17-year-old Brazilian children with listening difficulties who are at risk for auditory processing disorder, attention deficits and language learning challenges. PMID:35331656 | DOI:10.1016/j.bjorl. 2021.12.001 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Giving Children with Deafness a Cape: Amplifying Diverse Portrayals of Hearing Loss in Media

xlomafota13 shared this article with you from Inoreader Giving Children with Deafness a Cape: Amplifying Diverse Portrayals of Hearing Loss in Media Via ear nose throat Ear Nose Throat J. 2022 Mar 24:1455613221087941. doi: 10.1177/01455613221087941. Online ahead of print. NO ABSTRACT PMID:35331032 | DOI:10.1177/01455613221087941 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.