! ORL via Alexandros G.Sfakianakis on Inoreader: Nasal irrigation: From empiricism to evidence-based medicine. A review

! ORL via Alexandros G.Sfakianakis on Inoreader

Nasal irrigation: From empiricism to evidence-based medicine. A review Sep 4th 2015, 10:01 Publication date: Available online 3 September 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): P.-L. Bastier, A. Lechot, L. Bordenave, M. Durand, L. de Gabory Nasal irrigation plays a non-negligible role in the treatment of numerous sinonasal pathologies and postoperative care. There is, however, a wide variety of protocols. The present review of the evidence-based literature sought objective arguments for optimization and efficacy. It emerged that large-volume low-pressure nasal douche optimizes the distribution and cleansing power of the irrigation solution in the nasal cavity. Ionic composition and pH also influence mucociliary clearance and epithelium trophicity. Seawater is less rich in sodium ions and richer in bicarbonates, potassium, calcium and magnesium than is isotonic normal saline, while alkaline pH and elevated calcium concentration optimized ciliary motility in vitro. Bicarbonates reduce secretion viscosity. Potassium and magnesium promote healing and limit local inflammation. These results show that the efficacy of nasal irrigation is multifactorial. Large-volume low-pressure nasal irrigation using undiluted seawater seems, in the present state of knowledge, to be the most effective protocol.

You are receiving this email because you subscribed to this feed at blogtrottr.com. If you no longer wish to receive these emails, you can unsubscribe from this feed, or manage all your subscriptions