Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Δευτέρα 30 Νοεμβρίου 2015

OtoRhinoLaryngology & Medicine,New Articles,November 30th,2015


Anti-platelet Agents after Traumatic Intracranial Hemorrhage

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 λεπτό
Use of via Clinical Neurology and Neurosurgery [image: S03038467.gif] Publication date: Available online 28 November 2015 *Source:*Clinical Neurology and Neurosurgery Author(s): Keith Kerr, Christopher Wilkerson, Scott Shepard, Alex Choi, Ryan Kitagawa ObjectiveTo evaluate the risk of hemorrhagic complications associated with starting APT after acute tICH and to examine the frequency of thrombotic complications.Patients and MethodsWe retrospectively identified all patients admitted to our institution with tICH that received APT during their initial hospitalization over a three-year ... περισσότερα »

Dexmedetomidine and remifentanil on potential extreme haemodynamic and respiratory response following mask ventilation and laryngoscopy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 λεπτό
Comparison of the effects of dexmedetomidine and remifentanil on potential extreme haemodynamic and respiratory response following mask ventilation and laryngoscopy in patients with mandibular fractures: *OBJECTIVE:* The safety profile and efficacy were compared for remifentanil and dexmedetomidine with respect to haemodynamic and respiratory response during mask ventilation and laryngoscopy in patients with mandibular fractures. *PATIENTS AND METHODS:* Seventy patients undergoing elective mandibular fracture surgery were randomly assigned to the remifentanil group (Group R, n = 3...περισσότερα »

Orbital Indeterminate Lesions

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
in Adults: via Academic Radiology Publication date: Available online 28 November 2015 *Source:*Academic Radiology Author(s): Xiao-Quan Xu, Hao Hu, Guo-Yi Su, Ling Zhang, Hu Liu, Xun-Ning Hong, Hai-Bin Shi, Fei-Yun Wu Rationale and ObjectivesThe aim of this study was to evaluate the added value of histogram analysis of apparent diffusion coefficient (ADC) maps in differentiating indeterminate orbital malignant tumors from benign tumors, compared to using magnetic resonance (MR) morphological features alone.Materials and MethodsWe retrospectively evaluated 54 patients with orbital tumo...περισσότερα »

Nucleolin overexpression is associated with an unfavorable outcome for ependymoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Nucleolin overexpression is associated with an unfavorable outcome for ependymoma: a multifactorial analysis of 176 patients: AbstractEpendymoma typically has a better overall survival rate than most gliomas. Only a few comprehensive clinical studies have been published, but these are mostly from Western countries and use small sample sizes. Histopathological classification is not sufficient to show variable outcomes, and fails to show prognostic markers of the diverse outcomes; hence, it is essential to understand biological mechanisms. In this study, 176 ependymoma samples (World... περισσότερα »

Primary Asymptomatic Schwannoma in Thyroid Gland

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Unexpected Tumor: Primary Asymptomatic Schwannoma in Thyroid Gland: AbstractThe discovery of a tumor as a primary schwannoma in the thyroid gland is rare (Andrion et al. in Virchows Arch 413:367–372, 1988). It represents less than 1 % of mesenchymal neoplasms of this gland. Therefore, few cases of this type are described in medical literature (Aron et al. in Cytopathology 16:206–209, 2005; Cashman et al. in Medscape J Med 10(8):201, 2008; Coleman et al. in AJR Am J Roentgenol 140:383–7, 1983). In this article, we introduce the clinical case of a 27-year-old female patient, who pres...περισσότερα »

Malakoplakie de la glande sous-mandibulaire

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
chez un patient transplanté rénal via Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale Publication date: Available online 28 November 2015 *Source:*Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale Author(s): E. Schwob, J.-D. Bouaziz, A. Saussine, M. Bagot, A. Dionyssopoulos, A. Rigolet IntroductionLa malakoplakie (MP) est une granulomatose inflammatoire rare, survenant chez des patients immunodéprimés, en réponse à une infection à Escherichia coli. Les lésions sont le plus souvent localisées au tractus génito-urinaire, mais il existe ... περισσότερα »

Estimating needle tip deflection in biological tissue from a single transverse ultrasound image: application to brachytherapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Estimating needle tip deflection in biological tissue from a single transverse ultrasound image: application to brachytherapy: Abstract PurposeThis paper proposes a method to predict the deflection of a flexible needle inserted into soft tissue based on the observation of deflection at a single point along the needle shaft. MethodsWe model the needle-tissue as a discretized structure composed of several virtual, weightless, rigid links connected by virtual helical springs whose stiffness coefficient is found using a pattern search algorithm that only requires the force applied ... περισσότερα »

Electromagnetic navigated ultrasound bronchoscopy (EBUS)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
A novel platform for electromagnetic navigated ultrasound bronchoscopy (EBUS): Abstract PurposeEndobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) of mediastinal lymph nodes is essential for lung cancer staging and distinction between curative and palliative treatment. Precise sampling is crucial. Navigation and multimodal imaging may improve the efficiency of EBUS-TBNA. We demonstrate a novel EBUS-TBNA navigation system in a dedicated airway phantom. MethodsUsing a convex probe EBUS bronchoscope (CP-EBUS) with an integrated sensor for electromagnetic (EM) pos... περισσότερα »

Multimedia in the informed consent process for endoscopic sinus surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Multimedia in the informed consent process for endoscopic sinus surgery: A randomized control trial: Objectives/Hypothesis To determine patient recall of specific risks associated with endoscopic sinus surgery and whether an adjunct multimedia education module is an effective patient tool in enhancing the standard informed consent process. Study Design Prospective, randomized, controlled trial. Methods Fifty consecutive adult patients scheduled for endoscopic sinus surgery at a rhinology clinic of a tertiary care hospital were recruited for this study. Informed consent was studied by... περισσότερα »

Mixed Streptococcus pneumoniae and Streptococcus pyogenes meningitis

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Mixed Streptococcus pneumoniae and Streptococcus pyogenes meningitis in an immunocompromised adult patient: a case report: IntroductionCommunity-acquired meningitis is a monomicrobial infection caused by either viruses or bacteria in the vast majority of patients. We report here one exceptional case of a patient with mixed bacterial meningitis due to Streptococcus pneumoniae and Streptococcus pyogenes.Case presentationWe report the case of a 68-year-old immunocompromised Caucasian man suffering from otitis and then meningitis caused by Streptococcus pneumoniae and Streptococcus pyog... περισσότερα »

Materials, Vol. 8, Pages 8072-8086: Order Reconstruction in a Nanoconfined Nematic Liquid Crystal between Two Coaxial Cylinders

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
The dynamics of a disclination loop (s = ±1/2) in nematic liquid crystals constrained between two coaxial cylinders were investigated based on two-dimensional Landau–de Gennes tensorial formalism by using a finite-difference iterative method. The effect of thickness (d = R2 − R1, where R1 and R2 represent the internal and external radii of the cylindrical cavity, respectively) on the director distribution of the defect was simulated using different R1 values. The results show that the order reconstruction occurs at a critical value of dc, which decreases with increasing inner rati... περισσότερα »

Toxins, Vol. 7, Pages 5098-5113: A Venom Gland Extracellular Chitin-Binding-Like Protein from Pupal Endoparasitoid Wasps, Pteromalus Puparum, Selectively Binds Chitin

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Chitin-binding proteins (CBPs) are present in many species and they act in a variety of biological processes. We analyzed a Pteromalus puparum venom apparatus proteome and transcriptome and identified a partial gene encoding a possible CBP. Here, we report cloning a full-length cDNA of a sequence encoding a chitin-binding-like protein (PpCBP) from P. puparum, a pupal endoparasitoid of Pieris rapae. The cDNA encoded a 96-amino-acid protein, including a secretory signal peptide and a chitin-binding peritrophin-A domain. Phylogenetic analysis of chitin binding domains (CBDs) of cuticl... περισσότερα »

Transmission of Information in Neoplasia by Extracellular Vesicles

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
from #Medicine via ola Kala on Inoreader http://ift.tt/1lTBRdI via IFTTT

Corrigendum to “Strategy for the Management of Macular Edema in Retinal Vein Occlusion: The European VitreoRetinal Society Macular Edema Study”

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
from #Medicine via ola Kala on Inoreader http://ift.tt/1TmG2tF via IFTTT

Molecules, Vol. 20, Pages 21214-21231: Characterization of Global Transcriptome Using Illumina Paired-End Sequencing and Development of EST-SSR Markers in Two Species of Gynostemma (Cucurbitaceae)

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Gynostemma pentaphyllum is an important medicinal herb of the Cucurbitaceae family, but limited genomic data have hindered genetic studies. In this study, transcriptomes of two closely-related Gynostemma species, Gynostemma cardiospermum and G. pentaphyllum, were sequenced using Illumina paired-end sequencing technology. A total of 71,607 nonredundant unigenes were assembled. Of these unigenes, 60.45% (43,288) were annotated based on sequence similarity search with known proteins. A total of 11,059 unigenes were identified in the Kyoto Encyclopedia of Genes and Genomes Pathway (KE... περισσότερα »

Applied Sciences, Vol. 5, Pages 1457-1483: Quantum Wind Driven Optimization for Unmanned Combat Air Vehicle Path Planning

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Unmanned combat air vehicle (UCAV) path planning aims to calculate the optimal or suboptimal flight path considering the different threats and constraints under the complex battlefield environment. This flight path can help the UCAV avoid enemy threats and improve the efficiency of the investigation. This paper presents a new quantum wind driven optimization (QWDO) for the path planning of UCAV. QWDO algorithm uses quantum rotation gate strategy on population evolution and the quantum non-gate strategy to realize the individual variation of population. These operations improve the... περισσότερα »

IJMS, Vol. 16, Pages 28347-28376: miRNAs and Other Epigenetic Changes as Biomarkers in Triple Negative Breast Cancer

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Triple negative breast cancer (TNBC) is characterised by the lack of receptors for estrogen (ER), progesterone (PR), and human epidermal growth factor 2 (HER2). Since it cannot be treated by current endocrine therapies which target these receptors and due to its aggressive nature, it has one of the worst prognoses of all breast cancer subtypes. The only treatments remain chemo- and/or radio-therapy and surgery and because of this, novel biomarkers or treatment targets are urgently required to improve disease outcomes. MicroRNAs represent an attractive candidate for targeted therap...περισσότερα »

Applied Sciences, Vol. 5, Pages 1440-1456: 2D Saturable Absorbers for Fibre Lasers

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Two-dimensional (2D) nanomaterials are an emergent and promising platform for future photonic and optoelectronic applications. Here, we review recent progress demonstrating the application of 2D nanomaterials as versatile, wideband saturable absorbers for Q-switching and mode-locking fibre lasers. We focus specifically on the family of few-layer transition metal dichalcogenides, including MoS2, MoSe2 and WS2. from #Medicine via ola Kala on Inoreader http://ift.tt/1Xr73Sw via IFTTT

IJMS, Vol. 16, Pages 28320-28333: Gene Expression Profiles of Main Olfactory Epithelium in Adenylyl Cyclase 3 Knockout Mice

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα
Adenylyl Cyclase 3 (AC3) plays an important role in the olfactory sensation-signaling pathway in mice. AC3 deficiency leads to defects in olfaction. However, it is still unknown whether AC3 deficiency affects gene expression or olfactory signal transduction pathways within the main olfactory epithelium (MOE). In this study, gene microarrays were used to screen differentially expressed genes in MOE from AC3 knockout (AC3−/−) and wild-type (AC3+/+) mice. The differentially expressed genes identified were subjected to bioinformatic analysis and verified by qRT-PCR. Gene expression in...περισσότερα »

Molecules, Vol. 20, Pages 21204-21213: Metabolic Characteristics in Meal of Black Rapeseed and Yellow-Seeded Progeny of Brassica napus–Sinapis alba Hybrids

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα
Breeding of yellow-seeded rapeseed (Brassica napus) is preferred over black-seeded rapeseed for the desirable properties of the former. This study evaluated the metabolites and nutritive values of black-seeded rapeseed meal and yellow-seeded meal from the progeny of a B. napus–Sinapis alba hybrid. Yellow-seed meal presented higher protein (35.46% vs. 30.29%), higher sucrose (7.85% vs. 7.29%), less dietary fiber (26.19% vs. 34.63%) and crude fiber (4.56% vs. 8.86%), and less glucosinolates (22.18 vs. 28.19 μmol/g) than black-seeded one. Amounts of ash (3.65% vs. 4.55%), phytic acid...περισσότερα »

IJMS, Vol. 16, Pages 28311-28319: RpoN Regulates Virulence Factors of Pseudomonas aeruginosa via Modulating the PqsR Quorum Sensing Regulator

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
The alternative sigma factor RpoN regulates many cell functions, such as motility, quorum sensing, and virulence in the opportunistic pathogen Pseudomonas aeruginosa (P. aeruginosa). P. aeruginosa often evolves rpoN-negative variants during the chronic infection in cystic fibrosis patients. It is unclear how RpoN interacts with other regulatory mechanisms to control virulence of P. aeruginosa. In this study, we show that RpoN modulates the function of PqsR, a quorum sensing receptor regulating production of virulence factors including the phenazine pyocyanin. The ∆rpoN mutant is a... περισσότερα »

Animals, Vol. 5, Pages 1220-1232: Artificially Increased Yolk Hormone Levels and Neophobia in Domestic Chicks

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
In birds there is compelling evidence that the development and expression of behavior is affected by maternal factors, particularly via variation in yolk hormone concentrations of maternal origin. In the present study we tested whether variation in yolk hormone levels lead to variation in the expression of neophobia in young domestic chicks. Understanding how the prenatal environment could predispose chicks to express fear-related behaviors is essential in order to propose preventive actions and improve animal welfare. We simulated the consequences of a maternal stress by experime... περισσότερα »

Molecules, Vol. 20, Pages 21232-21253: Hydrothermal Conversion of Giant Reed to Furfural and Levulinic Acid: Optimization of the Process under Microwave Irradiation and Investigation of Distinctive Agronomic Parameters

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
The hydrothermal conversion of giant reed (Arundo donax L.) to furfural (FA) and levulinic acid (LA) was investigated in the presence of dilute hydrochloric acid. FA and LA yields were improved by univariate optimization of the main reaction parameters: concentration of the acid catalyst, solid/liquid ratio of the reaction mixture, hydrolysis temperature, and reaction time. The catalytic performances were investigated adopting the efficient microwave (MW) irradiation, allowing significant energy and time savings. The best FA and LA yields were further confirmed using a traditional... περισσότερα »

IJMS, Vol. 16, Pages 28334-28346: Carbon Ion Irradiated Neural Injury Induced the Peripheral Immune Effects in Vitro or in Vivo

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Carbon ion radiation is a promising treatment for brain cancer; however, the immune system involved long-term systemic effects evoke a concern of complementary and alternative therapies in clinical treatment. To clarify radiotherapy caused fundamental changes in peripheral immune system, examinations were performed based on established models in vitro and in vivo. We found that brain-localized carbon ion radiation of neural cells induced complex changes in the peripheral blood, thymus, and spleen at one, two, and three months after its application. Atrophy, apoptosis, and abnormal... περισσότερα »

Animals, Vol. 5, Pages 1207-1219: A Review of Different Stunning Methods for Poultry—Animal Welfare Aspects (Stunning Methods for Poultry)

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Electrical water bath stunning is the most commonly used method for poultry stunning prior to slaughter, but has been questioned on animal welfare and product quality grounds. Controlled atmosphere stunning (CAS) methods, involving a variety of gas mixtures, have become increasingly common, at least in Europe. CAS methods have been perceived as an improvement from an animal welfare perspective, partly because birds can be stunned without prior shackling, and are generally considered to result in improved product quality compared to water bath stunning. However, there would still be...περισσότερα »

IJMS, Vol. 16, Pages 28320-28333: Gene Expression Profiles of Main Olfactory Epithelium in Adenylyl Cyclase 3 Knockout Mice

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Adenylyl Cyclase 3 (AC3) plays an important role in the olfactory sensation-signaling pathway in mice. AC3 deficiency leads to defects in olfaction. However, it is still unknown whether AC3 deficiency affects gene expression or olfactory signal transduction pathways within the main olfactory epithelium (MOE). In this study, gene microarrays were used to screen differentially expressed genes in MOE from AC3 knockout (AC3−/−) and wild-type (AC3+/+) mice. The differentially expressed genes identified were subjected to bioinformatic analysis and verified by qRT-PCR. Gene expression in...περισσότερα »

Molecules, Vol. 20, Pages 21204-21213: Metabolic Characteristics in Meal of Black Rapeseed and Yellow-Seeded Progeny of Brassica napus–Sinapis alba Hybrids

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Breeding of yellow-seeded rapeseed (Brassica napus) is preferred over black-seeded rapeseed for the desirable properties of the former. This study evaluated the metabolites and nutritive values of black-seeded rapeseed meal and yellow-seeded meal from the progeny of a B. napus–Sinapis alba hybrid. Yellow-seed meal presented higher protein (35.46% vs. 30.29%), higher sucrose (7.85% vs. 7.29%), less dietary fiber (26.19% vs. 34.63%) and crude fiber (4.56% vs. 8.86%), and less glucosinolates (22.18 vs. 28.19 μmol/g) than black-seeded one. Amounts of ash (3.65% vs. 4.55%), phytic acid...περισσότερα »

IJERPH, Vol. 12, Pages 15129-15142: Feasibility of Measuring Tobacco Smoke Air Pollution in Homes: Report from a Pilot Study

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Tobacco smoke air pollution (TSAP) measurement may persuade parents to adopt smoke-free homes and thereby reduce harm to children from tobacco smoke in the home. In a pilot study involving 29 smoking families, a Sidepak was used to continuously monitor home PM2.5 during an 8-h period, Sidepak and/or Dylos monitors provided real-time feedback, and passive nicotine monitors were used to measure home air nicotine for one week. Feedback was provided to participants in the context of motivational interviews. Home PM2.5 levels recorded by continuous monitoring were not well-accepted by ...περισσότερα »

Sensors, Vol. 15, Pages 29882-29892: Identification of Chinese Herbs Using a Sequencing-Free Nanostructured Electrochemical DNA Biosensor

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Due to the nearly identical phenotypes and chemical constituents, it is often very challenging to accurately differentiate diverse species of a Chinese herbal genus. Although technologies including DNA barcoding have been introduced to help address this problem, they are generally time-consuming and require expensive sequencing. Herein, we present a simple sequencing-free electrochemical biosensor, which enables easy differentiation between two closely related Fritillaria species. To improve its differentiation capability using trace amounts of DNA sample available from herbal ext...περισσότερα »

IJERPH, Vol. 12, Pages 15075-15087: A Comparative Study on the Uptake and Toxicity of Nickel Added in the Form of Different Salts to Maize Seedlings

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
In soil ecotoxicological studies, a toxic metal is usually added in the form of either an inorganic or organic salt with relatively high solubility. Nitrate, chloride, acetate, or sulfate are commonly considered as valid options for that aim. However, recent studies have shown that different salts of the same metal at the same cationic concentration may exhibit different toxicities to plants and soil organisms. This information should be considered when selecting data to use for developing toxicological criteria for soil environment. A comparative study was carried out to evaluate... περισσότερα »

Sensors, Vol. 15, Pages 29871-29881: Temperature Effects on the Wind Direction Measurement of 2D Solid Thermal Wind Sensors

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
For a two-dimensional solid silicon thermal wind sensor with symmetrical structure, the wind speed and direction information can be derived from the output voltages in two orthogonal directions, i.e., the north-south and east-west. However, the output voltages in these two directions will vary linearly with the ambient temperature. Therefore, in this paper, a temperature model to study the temperature effect on the wind direction measurement has been developed. A theoretical analysis has been presented first, and then Finite Element Method (FEM) simulations have been performed. It... περισσότερα »

IJERPH, Vol. 12, Pages 15118-15128: Epidemiology of Unintentional Child Injuries in the Makwanpur District of Nepal: A Household Survey

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Secondary sources of information indicate that the proportion of child deaths due to injuries is increasing in Nepal. This study aimed to describe the epidemiology of unintentional injuries in children, explore risk factors and estimate the burden faced by families and the community in the Makwanpur district. We conducted a household survey in Makwanpur, covering 3441 households. Injuries that occurred during the 12 months before the survey and required treatment or caused the child to be unable to take part in usual activities for three or more days were included. We identified 19... περισσότερα »

IJMS, Vol. 16, Pages 28296-28310: The Importance of Caveolin-1 as Key-Regulator of Three-Dimensional Growth in Thyroid Cancer Cells Cultured under Real and Simulated Microgravity Conditions

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
We recently demonstrated that the CAV1 gene was down-regulated, when poorly differentiated thyroid FTC-133 cancer cells formed spheroids under simulated microgravity conditions. Here, we present evidence that the caveolin-1 protein is involved in the inhibition of spheroid formation, when confluent monolayers are exposed to microgravity. The evidence is based on proteins detected in cells and their supernatants of the recent spaceflight experiment: "NanoRacks-CellBox-Thyroid Cancer". The culture supernatant had been collected in a special container adjacent to the flight hardware ... περισσότερα »

IJERPH, Vol. 12, Pages 15110-15117: Occurrence and Profiles of the Artificial Endocrine Disruptor Bisphenol A and Natural Endocrine Disruptor Phytoestrogens in Urine from Children in China

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Background: Exposure to artificial or natural endocrine disruptors, such as bisphenol A (BPA) and phytoestrogens has been demonstrated to have health effects, especially in children. Biomonitoring of BPA and phytoestrogens in human urine can be used to assess the intake levels of these compounds. Methods: In this study, BPA and phytoestrogens in urine specimens (n = 256) collected from children in China were measured by liquid chromatography (LC)-tandem mass spectrometry (MS/MS). Results: BPA was detected in most specimens, with a geometric mean concentration of 1.58 ng/mL. For the...περισσότερα »

IJERPH, Vol. 12, Pages 15143-15153: The Geographic Distribution of Liver Cancer in Canada Does Not Associate with Cyanobacterial Toxin Exposure

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Background: The incidence of liver cancer has been increasing in Canada over the past decade, as has cyanobacterial contamination of Canadian freshwater lakes and drinking water sources. Cyanotoxins released by cyanobacteria have been implicated in the pathogenesis of liver cancer. Objective: To determine whether a geographic association exists between liver cancer and surrogate markers of cyanobacterial contamination of freshwater lakes in Canada. Methods: A negative binomial regression model was employed based on previously identified risk factors for liver cancer. Results: No a...περισσότερα »

IJERPH, Vol. 12, Pages 15100-15109: Assessment of the Phytotoxicity of Metal Oxide Nanoparticles on Two Crop Plants, Maize (Zea mays L.) and Rice (Oryza sativa L.)

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
In this study, the phytotoxicity of seven metal oxide nanoparticles(NPs)—titanium dioxide (nTiO2), silicon dioxide (nSiO2), cerium dioxide (nCeO2), magnetite (nFe3O4), aluminum oxide (nAl2O3), zinc oxide (nZnO) and copper oxide (nCuO)—was assessed on two agriculturally significant crop plants (maize and rice). The results showed that seed germination was not affected by any of the seven metal oxide NPs. However, at the concentration of 2000 mg·L−1, the root elongation was significantly inhibited by nCuO (95.73% for maize and 97.28% for rice), nZnO (50.45% for maize and 66.75% for ...περισσότερα »

IJERPH, Vol. 12, Pages 15088-15099: The Associations of Job Stress and Organizational Identification with Job Satisfaction among Chinese Police Officers: The Mediating Role of Psychological Capital

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Police officers' job satisfaction is an important issue for police force management, but insufficient research exists on the topic, especially in China. This study aimed to examine the associations of job stress and organizational identification with job satisfaction among Chinese police officers, and particularly the mediating role of psychological capital (PsyCap). A cross-sectional study was conducted in Liaoning Province of China during the period of September–October 2014. A set of self-administered questionnaires was distributed to 2514 police officers, and complete response... περισσότερα »

Is uremic pruritus still an important clinical problem in maintenance hemodialysis patients?

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 13 δευτερόλεπτα
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Comment on: ‘Efficacy of topical tacrolimus for oral lichen planus: real-life experience in a retrospective cohort of patients with a review of the literature’ by Ribero et al. (2015)

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 13 δευτερόλεπτα
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1lpnBJ9 via IFTTT

The significance of structured parental educational intervention on childhood atopic dermatitis: a randomized controlled trial

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 13 δευτερόλεπτα
Abstract Background Parental education is important in managing childhood chronic diseases. Objectives The aim of the study was to evaluate the effects of a short-term structured educational programme for parents of children with moderate to severe atopic dermatitis ( AD), aged 3 months to 7 years, on the clinical course of AD, parental stress, anxiety and the quality of family life. Methods One hundred thirty-four parents with AD children were recruited in a randomized controlled clinical trial at the Outpatient Unit of Pediatric Dermatology, Children's Hospital in Zagreb. The ... περισσότερα »

Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 14 δευτερόλεπτα
CANOMAD is a rare chronic neuropathy, characterized by chronic sensory ataxia and intermittent brain stem symptoms due to antidisialosyl antibodies. The disorder results in significant morbidity but is poorly understood and often misdiagnosed. We describe a unique case of CANOMAD, associated with involuntary movements of the face; patient reported exacerbations with citrus and chocolate and respiratory muscle weakness. Our patient was initially misdiagnosed with Miller Fisher Syndrome, highlighting the need for vigilance should neurological symptoms recur in patients initially dia...περισσότερα »

Primary Mucoepidermoid Carcinoma Arising from Ectopic Salivary Tissue within an Intraparotid Lymph Node

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Primary Mucoepidermoid Carcinoma Arising from Ectopic Salivary Tissue within an Intraparotid Lymph Node: Ectopic salivary tissue is commonly found in intraparotid and periparotid lymph nodes. Warthin tumor is the most common tumor arising in ectopic salivary gland tissue and in intraparotid lymph nodes. Although rare, neoplastic transformation of the ectopic salivary tissues is conceivable and other types of salivary gland neoplasms arising in intraparotid lymph nodes have been reported. Herein we report a rare case of a 32-year-old Kuwaiti male who presented with a mass in the righ...περισσότερα »

Giant Hypopharyngeal Fibrovascular Polyp

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Giant Hypopharyngeal Fibrovascular Polyp: A Case Report and Review of the Relevant Literature: Fibrovascular polyps occur most commonly in the cervical esophagus and are extremely rare in the hypopharynx. In this paper, we report a case of fibrovascular polyp of a 52-year-old female, who presented with progressive dysphagia and weight loss and regurgitating a mass from her mouth. By the endoscopic examination, a polyp covered by normal mucosa with a wide stalk was detected at the hypopharynx. The pedicle of the mass was identified under general anesthesia and the 13 × 3 × 2 cm mass ...περισσότερα »

Tacrolimus-Induced Cardiomyopathy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Tacrolimus-Induced Cardiomyopathy in an Adult Renal Transplant Recipient: Tacrolimus-induced cardiomyopathy (TICM) is a rare but serious adverse effect of tacrolimus, which has been described primarily in pediatric non-renal transplant recipients. We describe a case of TICM in an adult renal transplant recipient that resulted in allograft dysfunction and multiple hospital admissions for heart failure exacerbation. Prompt and complete reversal of TICM occurred after tacrolimus discontinuation. Although tacrolimus-induced cardiomyopathy is reversible, availability of alternative immu... περισσότερα »

EK Sign: A Wrinkling of Uvula and the Base of Uvula in Obstructive Sleep Apnea-Hypopnea Syndrome

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
EK Sign: A Wrinkling of Uvula and the Base of Uvula in Obstructive Sleep Apnea-Hypopnea Syndrome Abstract Introduction. Diagnosis of obstructive sleep apnea-hypopnea syndrome (OSAHS) is suspected in the presence of symptoms and/or pharyngeal alterations and skeletal abnormalities of maxilla and mandible. Our aim is to find a new clinical sign that leads to suspicion of OSAHS in snorers. Methods. We reviewed the clinical data of 69 snoring patients with or without OSAHS. We defined EK sign as the presence of horizontal wrinkling of uvula and the base of uvula and tried to correla... περισσότερα »

Microvascular decompression and MRI findings in trigeminal neuralgia and hemifacial spasm

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
. A single center experience via Clinical Neurology and Neurosurgery Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Patrick W. Hitchon, Mario Zanaty, Toshio Moritani, Ergun Uc, Connie L. Pieper, Wenzhuan He, Jennifer Noeller ObjectiveFor patients with medically unresponsive trigeminal neuralgia (TIC) and hemifacial spasm (HS), surgical microvascular decompression (MVD) is the procedure of choice. The authors of this report sought to review their outcomes with MVD in patients with TIC and HS, and the success of preoperative magnetic...περισσότερα »

Autonomic symptoms in hypertensive patients with post-acute minor ischemic stroke

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
Autonomic symptoms in hypertensive patients with post-acute minor ischemic stroke via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Juan Idiaquez, Hector Farias, Francisco Torres, Jorge Vega, David A. Low BackgroundMost studies regarding autonomic dysfunction in ischemic stroke are limited to heart rate and blood pressure changes during the acute phase. However, there are few data on quantitative assessment of autonomic symptoms. We sought to asses... περισσότερα »

Festination in patients with Parkinson's disease

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
Festination in Chinese patients with Parkinson's disease via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Ruwei Ou, Xiaoyan Guo, Qianqian Wei, Bei Cao, Jing Yang, Wei Song, Na Shao, Bi Zhao, Xueping Chen, Huifang Shang ObjectiveTo investigate the occurrence and clinical associations of festination in Chinese patients with Parkinson's disease (PD).MethodsA total of 480 PD patients were recruited in this cross-sectional study. Assessments scales incl... περισσότερα »

BacterioFiles 240 - Water Worms Make (carbon) Monoxide Meals

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
This episode: Marine worms and their microbial symbionts can live on the toxic gas carbon monoxide! Reminder: this is the last episode for at least a few weeks while I am wrapping up my PhD. See you again when I'm done! (11.1 MB, 12.1 minutes) from Infection via ola Kala on Inoreader http://ift.tt/1PmEtxm via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via paythelady61 on Inoreader http://ift.tt/1XCwmMe via IFTTT

Pre-operative image-based segmentation of the cranial nerves and blood vessels in microvascular decompression

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
: Can we prevent unnecessary explorations? via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Parviz Dolati, Alexandra Golby, Daniel Eichberg, Mohamad Abolfotoh, Ian F. Dunn, Srinivasan Mukundan, Mohamed M. Hulou, Ossama Al-Mefty ObjectivesThis study was conducted to validate the accuracy of image-based pre-operative segmentation using the gold standard endoscopic and microscopic findings for localization and pre-operative diagnosis of the offensive...περισσότερα »

High coincidence of pituitary adenoma in patients with ruptured Rathke's cleft cyst

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
Demonstration of high coincidence of pituitary adenoma in patients with ruptured Rathke's cleft cyst: Results of a prospective study via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Hidetoshi Ikeda, Genichiro Ohhashi ObjectiveRepeated chronic inflammation, such as under circumstances of ruptured Rathke's cleft cyst (RCC), is known as the fundamental basis of various pathological changes including neoplastic change, therefore to examine accurate inc... περισσότερα »

Spinal Ependymomas

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
Genetic and molecular distinctions in spinal ependymomas: A review via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Ian D. Connolly, Rohaid Ali, Yingmei Li, Melanie Hayden Gephart While gross total resection of spinal ependymomas prevents recurrence, this surgical result is not always possible. Increasing evidence suggests that ependymomas occurring in the spine are genetically distinct from those originating in the brain. Herein we review the most ... περισσότερα »

Spinal fractures in patients with ankylosing spondylitis

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
Management of via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Najib E. El Tecle, Kingsley O. Abode-Iyamah, Patrick W. Hitchon, Nader S. Dahdaleh Ankylosing spondlylitis is a seronegative spondyloarthropathy that primarily affects the spinal column and sacroiliac joints. With disease progression autofusion of the spinal column takes place. This combined with the brittle bone quality make patients prone to fractures and spinal cord injury. The typ...περισσότερα »

Prognostic markers for craniopharyngioma recurrence : Increased expression of HIF-1α and VEGF correlates with recurrence

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
Important via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Aatman Shah, Henry Jung Highlights • Craniopharyngioma markers that predict recurrence have not been identified. • Larger size and adherence to the hypothalamus correlated with recurrence. • Increased expression of HIF-1α and VEGF correlates with recurrence. from #Med Blogs by Alexandros G.Sfakianakis via paythelady61 on Inoreader http://ift.tt/1XqTbYs via IFTTT

Invasion-related molecules in the peritumoral brain

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
Expression pattern of via Clinical Neurology and Neurosurgery [image: S03038467.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Álmos Klekner, Gábor Hutóczki, József Virga, Judit Reményi-Puskár, Judit Tóth, Beáta Scholtz, Éva Csősz, Gergő Kalló, László Steiner, Tibor Hortobágyi, László Bognár ObjectiveThe effectiveness of therapy of intracerebral neoplasms is mainly influenced by the invasive behaviour of the tumour. The peritumoral invasion depends on the interaction between the tumour cells and the extracellular matrix (EC...περισσότερα »

Intracerebral hemorrhages in Deep brain stimulation surgeries

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
A detailed analysis of via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Mehmet Tonge, Linda Ackermans, Ersoy Kocabicak, Vivianne van Kranen-Mastenbroek, Mark Kuijf, Mayke Oosterloo, Pieter Kubben, Yasin Temel ObjectivesDeep brain stimulation is nowadays a frequently performed surgery in patients with movement disorders, intractable epilepsy, and severe psychiatric disorders. The most feared complication of this surgery is an intracerebral hemorrha... περισσότερα »

Surgical management of ventrally based lower cervical (subaxial) meningiomas through the lateral approach

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
: Report on 16 cases via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Hisham Adel Aboul-Enein, Wael Mahmoud Khidr, Khaled Mohamed Abdeen, Aly Abo Madawi ObjectivesSpinal meningiomas are benign and relatively rare tumors. These tumors present about only 25% of primary spinal tumors. Although spinal meningiomas are considered as slowly growing benign tumors, yet they may cause devastating neurological deficits rendering patients crippled. This study... περισσότερα »

The risk of meningitis in patients undergoing endoscopic endonasal transsphenoidal surgery

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
Efficacy of ultra-short single agent regimen antibiotic chemo-prophylaxis in reducing the risk of meningitis in patients undergoing endoscopic endonasal transsphenoidal surgery via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Teresa Somma, Alberto Enrico Maraolo, Felice Esposito, Luigi Maria Cavallo, Grazia Tosone, Raffaele Orlando, Paolo Cappabianca ObjectivesThe study aims to evaluate the incidence of infectious complications (namely meningitis) ... περισσότερα »

Effects of mandibular advancement surgery on the temporomandibular joint and muscular and articular adaptive changes

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
—a systematic review via Oral and Maxillofacial Surgery Publication date: Available online 28 November 2015 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): A. Bermell-Baviera, C. Bellot-Arcís, J.M. Montiel-Company, J.M. Almerich-Silla The objective of this study was to assess the anatomical changes to the condyle and articular disc following mandibular advancement surgery, the adaptation of the masticatory muscles, and the improvement or worsening of temporomandibular disorders (TMD) in patients with pre-existing disorders and those who developed them foll...περισσότερα »

Orienting versus inhibition in the Concealed Information Test: Different cognitive processes drive different physiological measures

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 16 δευτερόλεπτα
Abstract The Concealed Information Test (CIT) provides a valid tool for psychophysiological detection of concealed knowledge. However, its precise theoretical underpinnings remain a matter of debate. The differential physiological responses elicited by concealed, relevant items, relative to control items, were traditionally explained as reflecting an orienting response (OR). According to an alternative account, these responses reflect attempts to inhibit arousal. The present study examined whether and to what extent CIT detection efficiency is affected by instructions aimed at man...περισσότερα »

Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy: CANOMAD is a rare chronic neuropathy, characterized by chronic sensory ataxia and intermittent brain stem symptoms due to antidisialosyl antibodies. The disorder results in significant morbidity but is poorly understood and often misdiagnosed. We describe a unique case of CANOMAD, associated with involuntary movements of the face; patient reported exacerbations with citrus and chocolate and respiratory muscle weakness. Our patient was initially misdiagnosed with Miller Fisher Syndrome, highl... περισσότερα »

Intracerebral hemorrhages in Deep brain stimulation surgeries

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
A detailed analysis of via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Mehmet Tonge, Linda Ackermans, Ersoy Kocabicak, Vivianne van Kranen-Mastenbroek, Mark Kuijf, Mayke Oosterloo, Pieter Kubben, Yasin Temel ObjectivesDeep brain stimulation is nowadays a frequently performed surgery in patients with movement disorders, intractable epilepsy, and severe psychiatric disorders. The most feared complication of this surgery is an intracerebral hemorrhage... περισσότερα »

Pre-operative image-based segmentation of the cranial nerves and blood vessels in microvascular decompression

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
: Can we prevent unnecessary explorations? via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Parviz Dolati, Alexandra Golby, Daniel Eichberg, Mohamad Abolfotoh, Ian F. Dunn, Srinivasan Mukundan, Mohamed M. Hulou, Ossama Al-Mefty ObjectivesThis study was conducted to validate the accuracy of image-based pre-operative segmentation using the gold standard endoscopic and microscopic findings for localization and pre-operative diagnosis of the offensive v...περισσότερα »

The risk of meningitis in patients undergoing endoscopic endonasal transsphenoidal surgery

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Efficacy of ultra-short single agent regimen antibiotic chemo-prophylaxis in reducing the risk of meningitis in patients undergoing endoscopic endonasal transsphenoidal surgery via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Teresa Somma, Alberto Enrico Maraolo, Felice Esposito, Luigi Maria Cavallo, Grazia Tosone, Raffaele Orlando, Paolo Cappabianca ObjectivesThe study aims to evaluate the incidence of infectious complications (namely meningitis) wi... περισσότερα »

Surgical Management of Recurrent Tracheocarotid Fistula following Endovascular Stent Placement

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Surgical Management of Recurrent Tracheocarotid Fistula following Endovascular Stent Placement: We report the case of a 25-year-old woman who developed a tracheocarotid fistula secondary to an infected endovascular stent placed in the right carotid artery after the patient experienced hemorrhage on her first tracheostomy change. The patient originally had the tracheostomy placed at an outside hospital in September 2014, due to prolonged intubation after a motor vehicle accident. The patient presented to the otolaryngology service with an acute tracheal hemorrhage. This necessitated ... περισσότερα »

Deep Neck Infection and Descending Mediastinitis as a Complication of Propionibacterium acnes Odontogenic Infection

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Deep Neck Infection and Descending Mediastinitis as a Complication of Propionibacterium acnes Odontogenic Infection: Propionibacterium acnes is an anaerobic, Gram-positive bacterium which causes numerous types of infections. Isolated Propionibacterium acnes deep neck infections are very rare. We present an interesting case of deep neck infection complicated by descending mediastinitis of isolated Propionibacterium acnes infection. Propionibacterium acnes is an anaerobic, Gram-positive bacterium, comprising a large part of the skin flora of healthy individuals [1]. Propionibacteri...περισσότερα »

Ant venom proteins causing hypersensitivity reactions

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Current advances in ant venom proteins causing hypersensitivity reactions in the Asia-Pacific region via ScienceDirect Publication: Molecular Immunology Publication date: January 2016 *Source:*Molecular Immunology, Volume 69 Author(s): Hathairat Srisong, Sakda Daduang, Andreas L. Lopata The main insects causing allergy reactions to stinging insect in humans are Apidae (bees), Vespidae (wasps, yellow jackets and hornets) and Formicidae (ants). Their venom stings are composed of various biologically active peptides and protein components, some of which can cause toxicity or anaphylaxis i... περισσότερα »

Recurrent Guillain–Barré syndrome

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
presenting stereotypic manifestations, positive antiganglioside antibodies, and rapid recovery via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): So Young Pyun, Jin-Ho Jeong, Jong Seok Bae ObjectiveRecurrent Guillain–Barré syndrome (rGBS) has been described as a rare entity with distinct characteristics. However, little is known about rGBS in Asian group. The aim of this study was to identify the incidence and clinical course of rGBS, and to determine... περισσότερα »

Microvascular decompression and MRI findings in trigeminal neuralgia and hemifacial spasm

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
. A single center experience via Clinical Neurology and Neurosurgery Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Patrick W. Hitchon, Mario Zanaty, Toshio Moritani, Ergun Uc, Connie L. Pieper, Wenzhuan He, Jennifer Noeller ObjectiveFor patients with medically unresponsive trigeminal neuralgia (TIC) and hemifacial spasm (HS), surgical microvascular decompression (MVD) is the procedure of choice. The authors of this report sought to review their outcomes with MVD in patients with TIC and HS, and the success of preoperative magnetic ...περισσότερα »

Autonomic symptoms in hypertensive patients with post-acute minor ischemic stroke

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Autonomic symptoms in hypertensive patients with post-acute minor ischemic stroke via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Juan Idiaquez, Hector Farias, Francisco Torres, Jorge Vega, David A. Low BackgroundMost studies regarding autonomic dysfunction in ischemic stroke are limited to heart rate and blood pressure changes during the acute phase. However, there are few data on quantitative assessment of autonomic symptoms. We sought to assess ... περισσότερα »

Festination in patients with Parkinson's disease

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Festination in Chinese patients with Parkinson's disease via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Ruwei Ou, Xiaoyan Guo, Qianqian Wei, Bei Cao, Jing Yang, Wei Song, Na Shao, Bi Zhao, Xueping Chen, Huifang Shang ObjectiveTo investigate the occurrence and clinical associations of festination in Chinese patients with Parkinson's disease (PD).MethodsA total of 480 PD patients were recruited in this cross-sectional study. Assessments scales includ... περισσότερα »

BacterioFiles 240 - Water Worms Make (carbon) Monoxide Meals

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
This episode: Marine worms and their microbial symbionts can live on the toxic gas carbon monoxide! Reminder: this is the last episode for at least a few weeks while I am wrapping up my PhD. See you again when I'm done! (11.1 MB, 12.1 minutes) from Infection via ola Kala on Inoreader http://ift.tt/1PmEtxm via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via paythelady61 on Inoreader http://ift.tt/1XCwmMe via IFTTT

Pre-operative image-based segmentation of the cranial nerves and blood vessels in microvascular decompression

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
: Can we prevent unnecessary explorations? via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Parviz Dolati, Alexandra Golby, Daniel Eichberg, Mohamad Abolfotoh, Ian F. Dunn, Srinivasan Mukundan, Mohamed M. Hulou, Ossama Al-Mefty ObjectivesThis study was conducted to validate the accuracy of image-based pre-operative segmentation using the gold standard endoscopic and microscopic findings for localization and pre-operative diagnosis of the offensive v...περισσότερα »

High coincidence of pituitary adenoma in patients with ruptured Rathke's cleft cyst

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Demonstration of high coincidence of pituitary adenoma in patients with ruptured Rathke's cleft cyst: Results of a prospective study via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Hidetoshi Ikeda, Genichiro Ohhashi ObjectiveRepeated chronic inflammation, such as under circumstances of ruptured Rathke's cleft cyst (RCC), is known as the fundamental basis of various pathological changes including neoplastic change, therefore to examine accurate incid... περισσότερα »

Spinal Ependymomas

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Genetic and molecular distinctions in spinal ependymomas: A review via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Ian D. Connolly, Rohaid Ali, Yingmei Li, Melanie Hayden Gephart While gross total resection of spinal ependymomas prevents recurrence, this surgical result is not always possible. Increasing evidence suggests that ependymomas occurring in the spine are genetically distinct from those originating in the brain. Herein we review the most re... περισσότερα »

Spinal fractures in patients with ankylosing spondylitis

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Management of via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Najib E. El Tecle, Kingsley O. Abode-Iyamah, Patrick W. Hitchon, Nader S. Dahdaleh Ankylosing spondlylitis is a seronegative spondyloarthropathy that primarily affects the spinal column and sacroiliac joints. With disease progression autofusion of the spinal column takes place. This combined with the brittle bone quality make patients prone to fractures and spinal cord injury. The typic...περισσότερα »

Prognostic markers for craniopharyngioma recurrence : Increased expression of HIF-1α and VEGF correlates with recurrence

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Important via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Aatman Shah, Henry Jung Highlights • Craniopharyngioma markers that predict recurrence have not been identified. • Larger size and adherence to the hypothalamus correlated with recurrence. • Increased expression of HIF-1α and VEGF correlates with recurrence. from #Med Blogs by Alexandros G.Sfakianakis via paythelady61 on Inoreader http://ift.tt/1XqTbYs via IFTTT

Invasion-related molecules in the peritumoral brain

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Expression pattern of via Clinical Neurology and Neurosurgery [image: S03038467.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Álmos Klekner, Gábor Hutóczki, József Virga, Judit Reményi-Puskár, Judit Tóth, Beáta Scholtz, Éva Csősz, Gergő Kalló, László Steiner, Tibor Hortobágyi, László Bognár ObjectiveThe effectiveness of therapy of intracerebral neoplasms is mainly influenced by the invasive behaviour of the tumour. The peritumoral invasion depends on the interaction between the tumour cells and the extracellular matrix (ECM)...περισσότερα »

Intracerebral hemorrhages in Deep brain stimulation surgeries

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
A detailed analysis of via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Mehmet Tonge, Linda Ackermans, Ersoy Kocabicak, Vivianne van Kranen-Mastenbroek, Mark Kuijf, Mayke Oosterloo, Pieter Kubben, Yasin Temel ObjectivesDeep brain stimulation is nowadays a frequently performed surgery in patients with movement disorders, intractable epilepsy, and severe psychiatric disorders. The most feared complication of this surgery is an intracerebral hemorrhage... περισσότερα »

Surgical management of ventrally based lower cervical (subaxial) meningiomas through the lateral approach

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
: Report on 16 cases via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Hisham Adel Aboul-Enein, Wael Mahmoud Khidr, Khaled Mohamed Abdeen, Aly Abo Madawi ObjectivesSpinal meningiomas are benign and relatively rare tumors. These tumors present about only 25% of primary spinal tumors. Although spinal meningiomas are considered as slowly growing benign tumors, yet they may cause devastating neurological deficits rendering patients crippled. This study d... περισσότερα »

The risk of meningitis in patients undergoing endoscopic endonasal transsphenoidal surgery

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Efficacy of ultra-short single agent regimen antibiotic chemo-prophylaxis in reducing the risk of meningitis in patients undergoing endoscopic endonasal transsphenoidal surgery via Clinical Neurology and Neurosurgery [image: 1-s2.0-S0303846715X00114-cov150h.gif] Publication date: December 2015 *Source:*Clinical Neurology and Neurosurgery, Volume 139 Author(s): Teresa Somma, Alberto Enrico Maraolo, Felice Esposito, Luigi Maria Cavallo, Grazia Tosone, Raffaele Orlando, Paolo Cappabianca ObjectivesThe study aims to evaluate the incidence of infectious complications (namely meningitis) wi... περισσότερα »

Effects of mandibular advancement surgery on the temporomandibular joint and muscular and articular adaptive changes

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
—a systematic review via Oral and Maxillofacial Surgery Publication date: Available online 28 November 2015 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): A. Bermell-Baviera, C. Bellot-Arcís, J.M. Montiel-Company, J.M. Almerich-Silla The objective of this study was to assess the anatomical changes to the condyle and articular disc following mandibular advancement surgery, the adaptation of the masticatory muscles, and the improvement or worsening of temporomandibular disorders (TMD) in patients with pre-existing disorders and those who developed them follo... περισσότερα »

Orienting versus inhibition in the Concealed Information Test: Different cognitive processes drive different physiological measures

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Abstract The Concealed Information Test (CIT) provides a valid tool for psychophysiological detection of concealed knowledge. However, its precise theoretical underpinnings remain a matter of debate. The differential physiological responses elicited by concealed, relevant items, relative to control items, were traditionally explained as reflecting an orienting response (OR). According to an alternative account, these responses reflect attempts to inhibit arousal. The present study examined whether and to what extent CIT detection efficiency is affected by instructions aimed at mani...περισσότερα »

Factors associated with the severity of childhood rhinoconjunctivitis

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Factors associated with the severity of childhood rhinoconjunctivitis via Allergology International Publication date: Available online 29 November 2015 *Source:*Allergology International Author(s): Koichi Yoshida, Mari Sasaki, Yuichi Adachi, Toshiko Itazawa, Hiroshi Odajima, Hirohisa Saito, Akira Akasawa BackgroundAllergic rhinitis is one of the most common chronic diseases in children. Although it has a large impact on the patient's quality of life, little is known about the factors associated with its severity. The aim of this study was to assess the factors associated with the severi... περισσότερα »

Hen's egg (HE) allergy develops during infancy

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Natural history of immediate-type hen's egg allergy in Japanese children via Allergology International Publication date: Available online 28 November 2015 *Source:*Allergology International Author(s): Kiyotaka Ohtani, Sakura Sato, Akinori Syukuya, Tomoyuki Asaumi, Kiyotake Ogura, Yumi Koike, Katsuhito Iikura, Noriyuki Yanagida, Takanori Imai, Motohiro Ebisawa BackgroundHen's egg (HE) allergy develops during infancy. We investigated tolerance acquisition in Japanese children allergic to HE aging <6 years.MethodsIn this retrospective study, 226 children born in 2005 with a history of imm... περισσότερα »

Orienting versus inhibition in the Concealed Information Test: Different cognitive processes drive different physiological measures

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 26 δευτερόλεπτα
Abstract The Concealed Information Test (CIT) provides a valid tool for psychophysiological detection of concealed knowledge. However, its precise theoretical underpinnings remain a matter of debate. The differential physiological responses elicited by concealed, relevant items, relative to control items, were traditionally explained as reflecting an orienting response (OR). According to an alternative account, these responses reflect attempts to inhibit arousal. The present study examined whether and to what extent CIT detection efficiency is affected by instructions aimed at mani...περισσότερα »

Bee Venom Injections

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 54 δευτερόλεπτα
Effects of Bee Venom Injections at Acupoints on Neurologic Dysfunction Induced by Thoracolumbar Intervertebral Disc Disorders in Canines: A Randomized, Controlled Prospective Study: Intervertebral disk disease (IVDD) is a major spine disorder in canines that causes neurological dysfunction, particularly in the thoracolumbar area. Analgesic and anti-inflammatory drugs are typically used to reduce nociceptive signals to decrease canine suffering. Bee venom (BV) has been reported to exert anti-inflammatory and analgesic effects. Injection of BV at acupoints has been widely used to trea...περισσότερα »

IJERPH, Vol. 12, Pages 15129-15142: Feasibility of Measuring Tobacco Smoke Air Pollution in Homes: Report from a Pilot Study

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
Tobacco smoke air pollution (TSAP) measurement may persuade parents to adopt smoke-free homes and thereby reduce harm to children from tobacco smoke in the home. In a pilot study involving 29 smoking families, a Sidepak was used to continuously monitor home PM2.5 during an 8-h period, Sidepak and/or Dylos monitors provided real-time feedback, and passive nicotine monitors were used to measure home air nicotine for one week. Feedback was provided to participants in the context of motivational interviews. Home PM2.5 levels recorded by continuous monitoring were not well-accepted by ...περισσότερα »

Sensors, Vol. 15, Pages 29882-29892: Identification of Chinese Herbs Using a Sequencing-Free Nanostructured Electrochemical DNA Biosensor

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
Due to the nearly identical phenotypes and chemical constituents, it is often very challenging to accurately differentiate diverse species of a Chinese herbal genus. Although technologies including DNA barcoding have been introduced to help address this problem, they are generally time-consuming and require expensive sequencing. Herein, we present a simple sequencing-free electrochemical biosensor, which enables easy differentiation between two closely related Fritillaria species. To improve its differentiation capability using trace amounts of DNA sample available from herbal ext...περισσότερα »

IJERPH, Vol. 12, Pages 15075-15087: A Comparative Study on the Uptake and Toxicity of Nickel Added in the Form of Different Salts to Maize Seedlings

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
In soil ecotoxicological studies, a toxic metal is usually added in the form of either an inorganic or organic salt with relatively high solubility. Nitrate, chloride, acetate, or sulfate are commonly considered as valid options for that aim. However, recent studies have shown that different salts of the same metal at the same cationic concentration may exhibit different toxicities to plants and soil organisms. This information should be considered when selecting data to use for developing toxicological criteria for soil environment. A comparative study was carried out to evaluate... περισσότερα »

Sensors, Vol. 15, Pages 29871-29881: Temperature Effects on the Wind Direction Measurement of 2D Solid Thermal Wind Sensors

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
For a two-dimensional solid silicon thermal wind sensor with symmetrical structure, the wind speed and direction information can be derived from the output voltages in two orthogonal directions, i.e., the north-south and east-west. However, the output voltages in these two directions will vary linearly with the ambient temperature. Therefore, in this paper, a temperature model to study the temperature effect on the wind direction measurement has been developed. A theoretical analysis has been presented first, and then Finite Element Method (FEM) simulations have been performed. It... περισσότερα »

IJERPH, Vol. 12, Pages 15118-15128: Epidemiology of Unintentional Child Injuries in the Makwanpur District of Nepal: A Household Survey

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
Secondary sources of information indicate that the proportion of child deaths due to injuries is increasing in Nepal. This study aimed to describe the epidemiology of unintentional injuries in children, explore risk factors and estimate the burden faced by families and the community in the Makwanpur district. We conducted a household survey in Makwanpur, covering 3441 households. Injuries that occurred during the 12 months before the survey and required treatment or caused the child to be unable to take part in usual activities for three or more days were included. We identified 19... περισσότερα »

IJMS, Vol. 16, Pages 28296-28310: The Importance of Caveolin-1 as Key-Regulator of Three-Dimensional Growth in Thyroid Cancer Cells Cultured under Real and Simulated Microgravity Conditions

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
We recently demonstrated that the CAV1 gene was down-regulated, when poorly differentiated thyroid FTC-133 cancer cells formed spheroids under simulated microgravity conditions. Here, we present evidence that the caveolin-1 protein is involved in the inhibition of spheroid formation, when confluent monolayers are exposed to microgravity. The evidence is based on proteins detected in cells and their supernatants of the recent spaceflight experiment: "NanoRacks-CellBox-Thyroid Cancer". The culture supernatant had been collected in a special container adjacent to the flight hardware ... περισσότερα »

IJERPH, Vol. 12, Pages 15110-15117: Occurrence and Profiles of the Artificial Endocrine Disruptor Bisphenol A and Natural Endocrine Disruptor Phytoestrogens in Urine from Children in China

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
Background: Exposure to artificial or natural endocrine disruptors, such as bisphenol A (BPA) and phytoestrogens has been demonstrated to have health effects, especially in children. Biomonitoring of BPA and phytoestrogens in human urine can be used to assess the intake levels of these compounds. Methods: In this study, BPA and phytoestrogens in urine specimens (n = 256) collected from children in China were measured by liquid chromatography (LC)-tandem mass spectrometry (MS/MS). Results: BPA was detected in most specimens, with a geometric mean concentration of 1.58 ng/mL. For the...περισσότερα »

IJERPH, Vol. 12, Pages 15143-15153: The Geographic Distribution of Liver Cancer in Canada Does Not Associate with Cyanobacterial Toxin Exposure

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
Background: The incidence of liver cancer has been increasing in Canada over the past decade, as has cyanobacterial contamination of Canadian freshwater lakes and drinking water sources. Cyanotoxins released by cyanobacteria have been implicated in the pathogenesis of liver cancer. Objective: To determine whether a geographic association exists between liver cancer and surrogate markers of cyanobacterial contamination of freshwater lakes in Canada. Methods: A negative binomial regression model was employed based on previously identified risk factors for liver cancer. Results: No a...περισσότερα »

IJERPH, Vol. 12, Pages 15100-15109: Assessment of the Phytotoxicity of Metal Oxide Nanoparticles on Two Crop Plants, Maize (Zea mays L.) and Rice (Oryza sativa L.)

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
In this study, the phytotoxicity of seven metal oxide nanoparticles(NPs)—titanium dioxide (nTiO2), silicon dioxide (nSiO2), cerium dioxide (nCeO2), magnetite (nFe3O4), aluminum oxide (nAl2O3), zinc oxide (nZnO) and copper oxide (nCuO)—was assessed on two agriculturally significant crop plants (maize and rice). The results showed that seed germination was not affected by any of the seven metal oxide NPs. However, at the concentration of 2000 mg·L−1, the root elongation was significantly inhibited by nCuO (95.73% for maize and 97.28% for rice), nZnO (50.45% for maize and 66.75% for ...περισσότερα »

IJERPH, Vol. 12, Pages 15088-15099: The Associations of Job Stress and Organizational Identification with Job Satisfaction among Chinese Police Officers: The Mediating Role of Psychological Capital

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
Police officers' job satisfaction is an important issue for police force management, but insufficient research exists on the topic, especially in China. This study aimed to examine the associations of job stress and organizational identification with job satisfaction among Chinese police officers, and particularly the mediating role of psychological capital (PsyCap). A cross-sectional study was conducted in Liaoning Province of China during the period of September–October 2014. A set of self-administered questionnaires was distributed to 2514 police officers, and complete response... περισσότερα »

IJERPH, Vol. 12, Pages 15058-15074: Healthy versus Unhealthy Suppliers in Food Desert Neighborhoods: A Network Analysis of Corner Stores’ Food Supplier Networks

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
Background: Products in corner stores may be affected by the network of suppliers from which storeowners procure food and beverages. To date, this supplier network has not been well characterized. Methods: Using network analysis, we examined the connections between corner stores (n = 24) in food deserts of Baltimore City (MD, USA) and their food/beverage suppliers (n = 42), to determine how different store and supplier characteristics correlated. Results: Food and beverage suppliers fell into two categories: Those providing primarily healthy foods/beverages (n = 15) in the healthy ...περισσότερα »

Sensors, Vol. 15, Pages 29893-29909: Improved PPP Ambiguity Resolution Considering the Stochastic Characteristics of Atmospheric Corrections from Regional Networks

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 55 δευτερόλεπτα
With the increased availability of regional reference networks, Precise Point Positioning (PPP) can achieve fast ambiguity resolution (AR) and precise positioning by assimilating the satellite fractional cycle biases (FCBs) and atmospheric corrections derived from these networks. In such processing, the atmospheric corrections are usually treated as deterministic quantities. This is however unrealistic since the estimated atmospheric corrections obtained from the network data are random and furthermore the interpolated corrections diverge from the realistic corrections. This paper...περισσότερα »

Relationships between ground and airborne gamma-ray spectrometric survey data, North Ras Millan, Southern Sinai Peninsula, Egypt

Alexandros G. SfakianakisστοΑπεικονιστικήΠριν από 1 ώρα
[image: S0265931X.gif] [image: S0265931X.gif] [image: S0265931X.gif] Publication date: February 2016 *Source:*Journal of Environmental Radioactivity, Volume 152 Author(s): Mohamed A.S. Youssef In the last decades of years, there was considerable growth in the use of airborne gamma-ray spectrometry. With this growth, there was an increasing need to standardize airborne measurements, so that they can be independent of survey parameters. Acceptable procedures were developed for converting airborne to ground gamma-ray spectrometric measurements of total-count intensity as well as, pota... περισσότερα »

Mechanistic interpretation of the varying selectivity of Cesium-137 and potassium uptake by radish (Raphanus sativus L.) under field conditions near Chernobyl

Alexandros G. SfakianakisστοΑπεικονιστικήΠριν από 1 ώρα
[image: S0265931X.gif] [image: S0265931X.gif] [image: S0265931X.gif] Publication date: February 2016 *Source:*Journal of Environmental Radioactivity, Volume 152 Author(s): V.V. Prorok, O.I. Dacenko, L.A. Bulavin, L.V. Poperenko, P.J. White The selectivity of cation uptake by radish (Raphanus sativus L.) growing in the field near Chernobyl varies during the growth season. It is hypothesised that this is a consequence of variation in 137Cs (Csss) and potassium (Kss) concentrations in the soil solution or the amount of dissolved potassium available to the plants. In the experiments re... περισσότερα »

Correlation Network Analysis Reveals Relationships between MicroRNAs, Transcription Factor T-bet, and Deregulated Cytokine/Chemokine-Receptor Network in Pulmonary Sarcoidosis

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 1 ώρα
Sarcoidosis is an inflammatory granulomatous disease with unknown etiology driven by cytokines and chemokines. There is limited information regarding the regulation of cytokine/chemokine-receptor network in bronchoalveolar lavage (BAL) cells in pulmonary sarcoidosis, suggesting contribution of miRNAs and transcription factors. We therefore investigated gene expression of 25 inflammation-related miRNAs, 27 cytokines/chemokines/receptors, and a Th1-transcription factor T-bet in unseparated BAL cells obtained from 48 sarcoidosis patients and 14 control subjects using quantitative RT-P...περισσότερα »

The Hematopoietic Niche in Myeloproliferative Neoplasms

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 1 ώρα
Specialized microanatomical areas of the bone marrow provide the signals that are mandatory for the maintenance and regulation of hematopoietic stem cells (HSCs) and progenitor cells. A complex microenvironment adjacent to the marrow vasculature (vascular niche) and close to the endosteum (endosteal niche) harbors multiple cell types including mesenchymal stromal cells and their derivatives such as CAR cells expressing high levels of chemokines C-X-C motif ligand 12 and early osteoblastic lineage cells, endothelial cells, and megakaryocytes. The characterization of the cellular an...περισσότερα »

Knowledge, Attitudes, and Usage of Apitherapy for Disease Prevention and Treatment among Undergraduate Pharmacy Students in Lithuania

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Traditional medicine therapies are historically used worldwide for disease prevention and treatment purposes. Apitherapy is part of the traditional medicine based on bee product use. Complementary medicine practices which incorporate use of some traditional herbal, mineral, or animal kind substances very often are discussed with pharmacy professionals because these products are often sold in pharmacies as dietary supplements. This study is aimed at determining the attitude, knowledge, and practices of apitherapy among undergraduated pharmacy students (Master of Pharmacy) who alrea...περισσότερα »

Sensors, Vol. 15, Pages 29855-29870: Electromagnetic Modelling of Fiber Sensors for Low-Cost and High Sensitivity Temperature Monitoring

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
An accurate design of an innovative fiber optic temperature sensor is developed. The sensor is based on a cascade of three microstructured optical fibers (MOFs). In the first one a suitable cascade of long period gratings is designed into the core. A single mode intermediate and a rare-earth activated Fabry-Perot optical cavity are the other two sensor MOF sections. An exhaustive theoretic feasibility investigation is performed employing computer code. The complete set-up for temperature monitoring can be obtained by utilizing only a low cost pump diode laser at 980 nm wavelength ... περισσότερα »

Sensors, Vol. 15, Pages 29841-29854: Enhanced Two-Factor Authentication and Key Agreement Using Dynamic Identities in Wireless Sensor Networks

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Key agreements that use only password authentication are convenient in communication networks, but these key agreement schemes often fail to resist possible attacks, and therefore provide poor security compared with some other authentication schemes. To increase security, many authentication and key agreement schemes use smartcard authentication in addition to passwords. Thus, two-factor authentication and key agreement schemes using smartcards and passwords are widely adopted in many applications. Vaidya et al. recently presented a two-factor authentication and key agreement sche... περισσότερα »

Sensors, Vol. 15, Pages 29821-29840: Process Mining Methodology for Health Process Tracking Using Real-Time Indoor Location Systems

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
The definition of efficient and accurate health processes in hospitals is crucial for ensuring an adequate quality of service. Knowing and improving the behavior of the surgical processes in a hospital can improve the number of patients that can be operated on using the same resources. However, the measure of this process is usually made in an obtrusive way, forcing nurses to get information and time data, affecting the proper process and generating inaccurate data due to human errors during the stressful journey of health staff in the operating theater. The use of indoor location ... περισσότερα »

Orienting versus inhibition in the Concealed Information Test: Different cognitive processes drive different physiological measures

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract The Concealed Information Test (CIT) provides a valid tool for psychophysiological detection of concealed knowledge. However, its precise theoretical underpinnings remain a matter of debate. The differential physiological responses elicited by concealed, relevant items, relative to control items, were traditionally explained as reflecting an orienting response (OR). According to an alternative account, these responses reflect attempts to inhibit arousal. The present study examined whether and to what extent CIT detection efficiency is affected by instructions aimed at man...περισσότερα »

Renal anomalies in patients with turner syndrome: Is scintigraphy superior to ultrasound?

Alexandros G. SfakianakisστοEvolution of a geneΠριν από 1 ώρα
Renal anomalies are present in up to 30% of patients with Turner syndrome (TS). Renal ultrasound (U/S) detects anatomical renal anomalies only while renal scintigraphy detects anomalies, detects early renal malfunction, and estimates glomerular filtration rate (GFR). Thus, we aimed to assess frequency of renal abnormalities detected by scintigraphy in comparison to renal U/S in TS patients. Ninety TS patients were subjected to auxological assessment, measurement of serum creatinine; and renal U/S and scintigraphy. Renal U/S detected renal anomalies in 22.22% of patients versus 17... περισσότερα »

Elevated plasma oxytocin levels in children with Prader–Willi syndrome compared with healthy unrelated siblings

Alexandros G. SfakianakisστοEvolution of a geneΠριν από 1 ώρα
Prader–Willi syndrome (PWS) is a rare genetic disorder associated with distinct abnormal behaviors including hyperphagia, profound social deficits, and obsessive-compulsive tendencies. PWS males showed reduced oxytocin receptor (OTR) gene expression and density in the hypothalamic paraventricular nucleus that may play a role in PWS psychopathology. Oxytocin is an anorexigenic neuropeptide similar to vasopressin that is associated with social cognition and obsessive-compulsive behavior. To evaluate oxytocin biology in PWS, we examined overnight fasting plasma oxytocin levels in 23...περισσότερα »

IJERPH, Vol. 12, Pages 15058-15074: Healthy versus Unhealthy Suppliers in Food Desert Neighborhoods: A Network Analysis of Corner Stores’ Food Supplier Networks

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Background: Products in corner stores may be affected by the network of suppliers from which storeowners procure food and beverages. To date, this supplier network has not been well characterized. Methods: Using network analysis, we examined the connections between corner stores (n = 24) in food deserts of Baltimore City (MD, USA) and their food/beverage suppliers (n = 42), to determine how different store and supplier characteristics correlated. Results: Food and beverage suppliers fell into two categories: Those providing primarily healthy foods/beverages (n = 15) in the healthy ...περισσότερα »

Sensors, Vol. 15, Pages 29893-29909: Improved PPP Ambiguity Resolution Considering the Stochastic Characteristics of Atmospheric Corrections from Regional Networks

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
With the increased availability of regional reference networks, Precise Point Positioning (PPP) can achieve fast ambiguity resolution (AR) and precise positioning by assimilating the satellite fractional cycle biases (FCBs) and atmospheric corrections derived from these networks. In such processing, the atmospheric corrections are usually treated as deterministic quantities. This is however unrealistic since the estimated atmospheric corrections obtained from the network data are random and furthermore the interpolated corrections diverge from the realistic corrections. This paper...περισσότερα »

Knowledge, Attitudes, and Usage of Apitherapy for Disease Prevention and Treatment among Undergraduate Pharmacy Students in Lithuania

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Traditional medicine therapies are historically used worldwide for disease prevention and treatment purposes. Apitherapy is part of the traditional medicine based on bee product use. Complementary medicine practices which incorporate use of some traditional herbal, mineral, or animal kind substances very often are discussed with pharmacy professionals because these products are often sold in pharmacies as dietary supplements. This study is aimed at determining the attitude, knowledge, and practices of apitherapy among undergraduated pharmacy students (Master of Pharmacy) who alrea...περισσότερα »

Sensors, Vol. 15, Pages 29855-29870: Electromagnetic Modelling of Fiber Sensors for Low-Cost and High Sensitivity Temperature Monitoring

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
An accurate design of an innovative fiber optic temperature sensor is developed. The sensor is based on a cascade of three microstructured optical fibers (MOFs). In the first one a suitable cascade of long period gratings is designed into the core. A single mode intermediate and a rare-earth activated Fabry-Perot optical cavity are the other two sensor MOF sections. An exhaustive theoretic feasibility investigation is performed employing computer code. The complete set-up for temperature monitoring can be obtained by utilizing only a low cost pump diode laser at 980 nm wavelength ... περισσότερα »

A Corny Joke

Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 1 ώρα
from Anatomy Pathology via ola Kala on Inoreader http://ift.tt/1TfJsxJ via IFTTT

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