Protective effects of aloin on oxygen and glucose deprivation-induced injury in PC12 cells
Publication date: Available online 6 January 2016 *Source:*Brain Research Bulletin Author(s): Renyuan Chang, Ru Zhou, Xue Qi, Jing Wang, Fan Wu, Wenli Yang, Wannian Zhang, Tao Sun, Yuxiang Li, Jianqiang Yu The present study aims to determine whether aloin could protect cells from ischemic and reperfusion injury in vitro and to elucidate the related mechanisms. Oxygen and glucose deprivation model in PC12 cells was used in the present study. 2-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), lactate dehydrogenase (LDH) assay and Hoechst 33342 nuclear staining were us... περισσότερα »
Involvement of BDNF/ERK signaling in spontaneous recovery from trimethyltin-induced hippocampal neurotoxicity in mice
Publication date: Available online 6 January 2016 *Source:*Brain Research Bulletin Author(s): Sueun Lee, Miyoung Yang, Juhwan Kim, Yeonghoon Son, Jinwook Kim, Sohi Kang, Wooseok Ahn, Sung-Ho Kim, Jong-Choon Kim, Taekyun Shin, Hongbing Wang, Changjong Moona Trimethyltin (TMT) toxicity causes histopathological damage in the hippocampus and induces seizure behaviors in mice. The lesions and symptoms recover spontaneously over time; however, little is known about the precise mechanisms underlying this recovery from TMT toxicity. We investigated changes in the brain-derived neurotrophic ... περισσότερα »
Preconditioning of H2S inhalation protects against cerebral ischemia/reperfusion injury by induction of HSP70 through PI3K/Akt/Nrf2 pathway
Publication date: Available online 6 January 2016 *Source:*Brain Research Bulletin Author(s): Kangxiang Ji, Long Xue, Jiwei Cheng, Yu Bai It is of great importance to protect the brain against cerebral ischemia and reperfusion (I/R) injury, which leads to excitotoxicity, redox imbalance, inflammation and apoptosis; however, there is currently no effective treatment. The present study aimed to investigate the effect of H2S preconditioning on cerebral I/R injury and its underlying mechanism. The results demonstrated that H2S preconditioning significantly prevented the development of n... περισσότερα »
Serotonin receptor antagonists increase fast ripple activity in rats treated with kainic acid.
Publication date: Available online 6 January 2016 *Source:*Brain Research Bulletin Author(s): Carla García-Barba, Laura Medina-Ceja Fast ripples (FR, 250–600Hz) are field potentials that occur only in those areas capable of generating seizures, such as the hippocampus, and modulation of FR by serotonin has been reported. Therefore, we hypothesized that the receptor antagonists 5HT1A and 5HT2A, B, C will increase FR in rats treated with kainic acid (KA, 0.8μg/0.5μl). For this purpose, the intracranial EEG recordings of the hippocampus from animals treated with KA and the serotonin an...περισσότερα »
Network mechanisms of intentional learning
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Adam Hampshire, Peter J. Hellyer, Beth Parkin, Nole Hiebert, Penny MacDonald, Adrian M. Owen, Robert Leech, James Rowe The ability to learn new tasks rapidly is a prominent characteristic of human behaviour. This ability relies on flexible cognitive systems that adapt in order to encode temporary programs for processing non-automated tasks. Previous functional imaging studies have revealed distinct roles for the lateral frontal cortices (LFCs) and the ventral striatum in intentional ... περισσότερα »
Temperature dependence of water diffusion pools in brain white matter
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Bibek Dhital, Christian Labadie, Frank Stallmach, Harald E. Möller, Robert Turner Water diffusion in brain tissue can now be easily investigated using magnetic resonance (MR) techniques, providing unique insights into cellular level microstructure such as axonal orientation. The diffusive motion in white matter is known to be non-Gaussian, with increasing evidence for more than one water-containing tissue compartment. In this study, freshly excised porcine brain white matter was meas...περισσότερα »
Decisions about the past are guided by reinstatement of specific memories in the hippocampus and perirhinal cortex
Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Michael L. Mack, Alison R. Preston When faced with a new challenge, we often reflect on related past experiences to guide our behavior. The ability to retrieve memories that overlap with current experience, a process known as pattern completion, is theorized as a critical function of the hippocampus. Although this view has influenced research for decades, there is little empirical support for hippocampal pattern completion to individual memory elements and its influence on behavior. We used pattern analysi... περισσότερα »
Kernel regression estimation of fiber orientation mixtures in diffusion MRI
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Ryan P. Cabeen, Mark E. Bastin, David H. Laidlaw We present and evaluate a method for kernel regression estimation of fiber orientations and associated volume fractions for diffusion MR tractography and population-based atlas construction in clinical imaging studies of brain white matter. This is a model-based image processing technique in which representative fiber models are estimated from collections of component fiber models in model-valued image data. This extends prior work in ...περισσότερα »
Visual motion transforms visual space representations similarly throughout the human visual hierarchy
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Ben M. Harvey, Serge O. Dumoulin Several studies demonstrate that visual stimulus motion affects neural receptive fields and fMRI response amplitudes. Here we unite results of these two approaches and extend them by examining the effects of visual motion on neural position preferences throughout the hierarchy of human visual field maps. We measured population receptive field (pRF) properties using high-field fMRI (7T), characterizing position preferences simultaneously over large reg...περισσότερα »
MUSE: MUlti-atlas region Segmentation utilizing Ensembles of registration algorithms and parameters, and locally optimal atlas selection
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Jimit Doshi, Guray Erus, Yangming Ou, Susan M. Resnick, Ruben C. Gur, Raquel E. Gur, Theodore D. Satterthwaite, Susan Furth, Christos Davatzikos Atlas-based automated anatomical labeling is a fundamental tool in medical image segmentation, as it defines regions of interest for subsequent analysis of structural and functional image data. The extensive investigation of multi-atlas warping and fusion techniques over the past 5 or more years has clearly demonstrated the advantages of con...περισσότερα »
Functional connectivity MRI tracks memory networks after maze learning in rodents
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Fatima A. Nasrallah, Xuan Vinh To, Der-Yow Chen, Aryeh Routtenberg, Kai-Hsiang Chuang Learning and memory employs a series of cognitive processes which require the coordination of multiple areas across the brain. However in vivo imaging of cognitive function has been challenging in rodents. Since these processes involve synchronous firing among different brain loci we explored functional connectivity imaging with resting-state fMRI. After 5-day training on a hidden platform watermaze...περισσότερα »
Thinking about thinking: Neural mechanisms and effects on memory
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Corinna Bonhage, Friederike Weber, Cornelia Exner, Philipp Kanske It is a well-established finding that memory encoding is impaired if an external secondary task (e.g. tone discrimination) is performed simultaneously. Yet, while studying we are also often engaged in internal secondary tasks such as planning, ruminating, or daydreaming. It remains unclear whether such a secondary internal task has similar effects on memory and what the neural mechanisms underlying such an influence are...περισσότερα »
Acceptance of evidence-supported hypotheses generates a stronger signal from an underlying functionally-connected network
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): J.C. Whitman, Y. Takane, T.P.L. Cheung, A. Moiseev, U. Ribary, L.M. Ward, T.S. Woodward Choosing one's preferred hypothesis requires multiple brain regions to work in concert as a functionally connected network. We predicted that a stronger network signal would underlie cognitive coherence between a hypothesis and the available evidence. In order to identify such functionally connected networks in magnetoencephalography (MEG) data, we first localized the generators of changes in osci...περισσότερα »
Something to sink your teeth into: The presence of teeth augments ERPs to mouth expressions
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Elizabeth B. daSilva, Kirsten Crager, Danika Geisler, Powell Newbern, Benjamin Orem, Aina Puce If the whites of the sclera can impact neural processing of eye expressions (Hardee, Thompson, & Puce, 2008; Whalen et al., 1998), do seen teeth affect neural responses to mouth expressions? Twenty participants (10 females; ages 22–31) viewed avatar mouth images depicting grimaces, smiles and open mouth expressions that were presented with and without teeth. A continuous 256 channel electro... περισσότερα »
Impulse source localization in an urban environment: Time reversal versus time matching
This study investigates two approaches for localizing an impulse sound source with distributed sensors in an urban environment under controlled processing time. In both approaches, the numerical model used for calculating the sound propagation is a finite-difference time-domain(FDTD) model. The simulations are drastically accelerated by restricting to the lower frequencies of the impulse signals and are evaluated against in situ measurements. The first tested localization technique relies on the time reversal of the measurements with the model. In the second technique, the source i...περισσότερα »
Sub-harmonic broadband humps and tip noise in low-speed ring fans
A joint experimental and numerical study has been achieved on a low-speed axial ring fan in clean inflow. Experimental evidence shows large periodic broadband humps at lower frequencies than the blade passing frequencies and harmonics even at design conditions. These sub-harmonic humps are also found to be sensitive to the fan process and consequently to its tip geometry. Softer fans yield more intense humps more shifted to lower frequencies with respect to the fan harmonics. Unsteady turbulent flow simulations of this ring fan mounted on a test plenum have been achieved by four d... περισσότερα »
In-plane and out-of-plane motions of the human tympanic membrane
Computer-controlled digital holographic techniques are developed and used to measure shape and four-dimensional nano-scale displacements of the surface of the tympanic membrane (TM) in cadaveric human ears in response to tonal sounds. The combination of these measurements (shape and sound-induced motions) allows the calculation of the out-of-plane (perpendicular to the surface) and in-plane (tangential) motion components at over 1 000 000 points on the TM surface with a high-degree of accuracy and sensitivity. A general conclusion is that the in-plane motion components are 10–20 d...περισσότερα »
Acoustic impedance of micro perforated membranes: Velocity continuity condition at the perforation boundary
The classic analytical model for the sound absorption of micro perforated materials is well developed and is based on a boundary condition where the velocity of the material is assumed to be zero, which is accurate when the material vibration is negligible. This paper develops an analytical model for finite-sized circular micro perforated membranes (MPMs) by applying a boundary condition such that the velocity of air particles on the hole wall boundary is equal to the membrane vibrationvelocity (a zero-slip condition). The acoustic impedance of the perforation, which varies with it... περισσότερα »
Quantifying spinal gait kinematics using an enhanced optical motion capture approach in adolescent idiopathic scoliosis
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Stefan Schmid, Daniel Studer, Carol-Claudius Hasler, Jacqueline Romkes, William R. Taylor, Silvio Lorenzetti, Reinald Brunner Background and purposeThe pathogenesis of adolescent idiopathic scoliosis (AIS) remains poorly understood. Previous research has indicated possible relationships between kinematics of the spine, pelvis and lower extremities during gait and the progression of AIS, but adequate evidence on spinal kinematics is lacking. The aim of this study was to provide a detailed assessment of spinal...περισσότερα »
Schooling Relates to Mental Health Problems in Adolescents with Cochlear Implants-Mediation by Hearing and Family Variables.
*Schooling Relates to Mental Health Problems in Adolescents with Cochlear Implants-Mediation by Hearing and Family Variables.* Front Psychol. 2015;6:1889 Authors: Huber M, Pletzer B, Giourgas A, Nickisch A, Kunze S, Illg A Abstract Aim of this multicenter study was to investigate whether schooling relates to mental health problems of adolescents with cochlear implants (CI) and how this relationship is mediated by hearing and family variables. One hundred and forty secondary school students with CI (mean age = 14.7 years, SD = 1.5), their hearing parents and teachers completed the ...περισσότερα »
Does providing real-time augmented feedback affect the performance of repeated lower limb loading to exhaustion?
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Amitabh Gupta, Ryan J. Hilliard, Kurt L. Mudie, Peter J. Clothier IntroductionThis study aimed to determine whether real-time augmented feedback influenced performance of single-leg hopping to volitional exhaustion.MethodsTwenty-seven healthy, male participants performed single-leg hopping (2.2Hz) with (visual and tactile feedback for a target hop height) or without feedback on a force plate. Repeated measures ANOVA were used to determine differences in vertical stiffness (k), duration of flight (tf) and loa... περισσότερα »
Analysis of incidence and genetic predisposition of preauricular sinus.
[image: http:--linkinghub.elsevier.com-ihub-imag]Related Articles *Analysis of incidence and genetic predisposition of preauricular sinus.* Int J Pediatr Otorhinolaryngol. 2014 Dec;78(12):2255-7 Authors: An SY, Choi HG, Lee JS, Kim JH, Yoo SW, Park B Abstract OBJECTIVES: To evaluate the incidence of preauricular sinus, the association between preauricular sinus of a parent and their children, and the odds of hearing impairments in patients with preauricular sinus. METHODS: A cross-sectional study was performed using data from the Korea National Health and Nutrition Examination Survey...περισσότερα »
Long term gait outcomes of surgically treated idiopathic toe walkers
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Mark L. McMulkin, Andi B. Gordon, Bryan J. Tompkins, Paul M. Caskey, Glen O. Baird Toe walking is a common gait deviation which in the absence of a known cause is termed idiopathic toe walking. Surgical treatment in the presence of a triceps surae contracture includes tendo-Achilles or gastrocnemius/soleus recession and has been shown to be effective in improving kinematic outcomes at a one year follow up. The purpose of this study was to assess longer term kinematic and kinetic outcomes of children with id... περισσότερα »
Quantifying spinal gait kinematics using an enhanced optical motion capture approach in adolescent idiopathic scoliosis
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Stefan Schmid, Daniel Studer, Carol-Claudius Hasler, Jacqueline Romkes, William R. Taylor, Silvio Lorenzetti, Reinald Brunner Background and purposeThe pathogenesis of adolescent idiopathic scoliosis (AIS) remains poorly understood. Previous research has indicated possible relationships between kinematics of the spine, pelvis and lower extremities during gait and the progression of AIS, but adequate evidence on spinal kinematics is lacking. The aim of this study was to provide a detailed assessment of spinal...περισσότερα »
Age-related decline of gait variability in children with attention-deficit/hyperactivity disorder: Support for the maturational delay hypothesis in gait
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Olivia Manicolo, Alexander Grob, Sakari Lemola, Priska Hagmann-von Arx BackgroundPrevious findings showed a tendency toward higher gait variability in children with attention-deficit/hyperactivity disorder (ADHD) compared to controls. This study examined whether gait variability in children with ADHD eventually approaches normality with increasing age (delay hypothesis) or whether these gait alterations represent a persistent deviation from typical development (deviation hypothesis).MethodThis cross-section...περισσότερα »
Does providing real-time augmented feedback affect the performance of repeated lower limb loading to exhaustion?
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Amitabh Gupta, Ryan J. Hilliard, Kurt L. Mudie, Peter J. Clothier IntroductionThis study aimed to determine whether real-time augmented feedback influenced performance of single-leg hopping to volitional exhaustion.MethodsTwenty-seven healthy, male participants performed single-leg hopping (2.2Hz) with (visual and tactile feedback for a target hop height) or without feedback on a force plate. Repeated measures ANOVA were used to determine differences in vertical stiffness (k), duration of flight (tf) and loa... περισσότερα »
The reliability of local dynamic stability in walking while texting and performing an arithmetical problem
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Dennis Hamacher, Daniel Hamacher, Alexander Törpel, Martin Krowicki, Fabian Herold, Lutz Schega In the recent years, local dynamic stability of walking was frequently used to quantify motor control. Particularly, dual-task paradigms are used to assess a shift in gait control strategy to test walking in real life situations. Texting short messages while walking is a common motor-cognitive dual task of daily living. To able to monitor possible intervention effects on motor-cognitive dual-task performance, the ... περισσότερα »
Long term gait outcomes of surgically treated idiopathic toe walkers
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Mark L. McMulkin, Andi B. Gordon, Bryan J. Tompkins, Paul M. Caskey, Glen O. Baird Toe walking is a common gait deviation which in the absence of a known cause is termed idiopathic toe walking. Surgical treatment in the presence of a triceps surae contracture includes tendo-Achilles or gastrocnemius/soleus recession and has been shown to be effective in improving kinematic outcomes at a one year follow up. The purpose of this study was to assess longer term kinematic and kinetic outcomes of children with id... περισσότερα »
Impaired synergic control of posture in Parkinson's patients without postural instability
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Ali Falaki, Xuemei Huang, Mechelle M. Lewis, Mark L. Latash BackgroundPostural instability is one of most disabling motor symptoms in Parkinson's disease. Indices of multi-muscle synergies are new measurements of movement and postural stability.ObjectivesMulti-muscle synergies stabilizing vertical posture were studied in Parkinson's disease patients without clinical symptoms of postural instability (Hoehn-Yahr≤II) and age-matched controls. We tested the hypothesis that both synergy indices during quiet stand... περισσότερα »
Age-related decline of gait variability in children with attention-deficit/hyperactivity disorder: Support for the maturational delay hypothesis in gait
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Olivia Manicolo, Alexander Grob, Sakari Lemola, Priska Hagmann-von Arx BackgroundPrevious findings showed a tendency toward higher gait variability in children with attention-deficit/hyperactivity disorder (ADHD) compared to controls. This study examined whether gait variability in children with ADHD eventually approaches normality with increasing age (delay hypothesis) or whether these gait alterations represent a persistent deviation from typical development (deviation hypothesis).MethodThis cross-section...περισσότερα »
Manipulating walking path configuration influences gait variability and six-minute walk test outcomes in older and younger adults
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): C.T. Barnett, M. Bisele, J.S. Jackman, T. Rayne, N.C. Moore, J.L. Spalding, P. Richardson, B. Plummer This study determined whether manipulations to walking path configuration influenced six-minute walk test (6MWT) outcomes and assessed how gait variability changes over the duration of the 6MWT in different walking path configurations. Healthy older (ODR) and younger (YNG) (n=24) adults completed familiarisation trials and five randomly ordered experimental trials of the 6MWT with walking configurations of; ...περισσότερα »
The reliability of local dynamic stability in walking while texting and performing an arithmetical problem
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Dennis Hamacher, Daniel Hamacher, Alexander Törpel, Martin Krowicki, Fabian Herold, Lutz Schega In the recent years, local dynamic stability of walking was frequently used to quantify motor control. Particularly, dual-task paradigms are used to assess a shift in gait control strategy to test walking in real life situations. Texting short messages while walking is a common motor-cognitive dual task of daily living. To able to monitor possible intervention effects on motor-cognitive dual-task performance, the ... περισσότερα »
Relationship between maximum isometric joint moment and functional task performance in patients with brachial plexus injury: A pilot study
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Dustin L. Crouch, Anthony C. Santago, Johannes F. Plate, Zhongyu Li, Katherine R. Saul We evaluated whether subjects with brachial plexus injury (BPI) adapted their movements to reduce the mechanical demand on their impaired upper extremity. In 6 subjects with unilateral BPI with C5 and C6 involvement, we measured bilateral maximum isometric shoulder and elbow strength, and computed joint kinematics and net muscle-generated joint moments during 7 unimanual functional tasks. Compared to the unimpaired extremi... περισσότερα »
Impaired synergic control of posture in Parkinson's patients without postural instability
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Ali Falaki, Xuemei Huang, Mechelle M. Lewis, Mark L. Latash BackgroundPostural instability is one of most disabling motor symptoms in Parkinson's disease. Indices of multi-muscle synergies are new measurements of movement and postural stability.ObjectivesMulti-muscle synergies stabilizing vertical posture were studied in Parkinson's disease patients without clinical symptoms of postural instability (Hoehn-Yahr≤II) and age-matched controls. We tested the hypothesis that both synergy indices during quiet stand... περισσότερα »
Manipulating walking path configuration influences gait variability and six-minute walk test outcomes in older and younger adults
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): C.T. Barnett, M. Bisele, J.S. Jackman, T. Rayne, N.C. Moore, J.L. Spalding, P. Richardson, B. Plummer This study determined whether manipulations to walking path configuration influenced six-minute walk test (6MWT) outcomes and assessed how gait variability changes over the duration of the 6MWT in different walking path configurations. Healthy older (ODR) and younger (YNG) (n=24) adults completed familiarisation trials and five randomly ordered experimental trials of the 6MWT with walking configurations of; ...περισσότερα »
Relationship between maximum isometric joint moment and functional task performance in patients with brachial plexus injury: A pilot study
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Dustin L. Crouch, Anthony C. Santago, Johannes F. Plate, Zhongyu Li, Katherine R. Saul We evaluated whether subjects with brachial plexus injury (BPI) adapted their movements to reduce the mechanical demand on their impaired upper extremity. In 6 subjects with unilateral BPI with C5 and C6 involvement, we measured bilateral maximum isometric shoulder and elbow strength, and computed joint kinematics and net muscle-generated joint moments during 7 unimanual functional tasks. Compared to the unimpaired extremi... περισσότερα »
Quantifying spinal gait kinematics using an enhanced optical motion capture approach in adolescent idiopathic scoliosis
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Stefan Schmid, Daniel Studer, Carol-Claudius Hasler, Jacqueline Romkes, William R. Taylor, Silvio Lorenzetti, Reinald Brunner Background and purposeThe pathogenesis of adolescent idiopathic scoliosis (AIS) remains poorly understood. Previous research has indicated possible relationships between kinematics of the spine, pelvis and lower extremities during gait and the progression of AIS, but adequate evidence on spinal kinematics is lacking. The aim of this study was to provide a detailed assessment of spinal...περισσότερα »
Does providing real-time augmented feedback affect the performance of repeated lower limb loading to exhaustion?
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Amitabh Gupta, Ryan J. Hilliard, Kurt L. Mudie, Peter J. Clothier IntroductionThis study aimed to determine whether real-time augmented feedback influenced performance of single-leg hopping to volitional exhaustion.MethodsTwenty-seven healthy, male participants performed single-leg hopping (2.2Hz) with (visual and tactile feedback for a target hop height) or without feedback on a force plate. Repeated measures ANOVA were used to determine differences in vertical stiffness (k), duration of flight (tf) and loa... περισσότερα »
Long term gait outcomes of surgically treated idiopathic toe walkers
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Mark L. McMulkin, Andi B. Gordon, Bryan J. Tompkins, Paul M. Caskey, Glen O. Baird Toe walking is a common gait deviation which in the absence of a known cause is termed idiopathic toe walking. Surgical treatment in the presence of a triceps surae contracture includes tendo-Achilles or gastrocnemius/soleus recession and has been shown to be effective in improving kinematic outcomes at a one year follow up. The purpose of this study was to assess longer term kinematic and kinetic outcomes of children with id... περισσότερα »
Distribution and antimicrobial resistance pattern of equine uterine bacterial isolates
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Can sliding-window correlations reveal dynamic functional connectivity in resting-state fMRI?
Publication date: 15 February 2016 Source:NeuroImage, Volume 127 Author(s): R. Hindriks, M.H. Adhikari, Y. Murayama, M. Ganzetti, D. Mantini, N.K. Logothetis, G. Deco During the last several years, the focus of research on resting-state functional magnetic resonance imaging (fMRI) has shifted from the analysis of functional connectivity averaged over the duration of scanning sessions to… Continue reading Can sliding-window correlations reveal dynamic functional connectivity in resting-state fMRI?
Former ministers call for commission to review NHS and social care funding
Three former health ministers have called for a cross party commission to be established to review future funding of the NHS and social care in England.The proposal by the Liberal Democrat former… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RbUo22 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Uz6aBJ via IFTTT… Continue reading Former ministers call for commission to review NHS and social care funding
Large diameter shafts for underground infrastructure
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Identification of factors associated with the gestational length in horses
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When opportunity meets motivation: Neural engagement during social approach is linked to high approach motivation
Publication date: 15 February 2016 Source:NeuroImage, Volume 127 Author(s): Sina Radke, Eva-Maria Seidel, Simon B. Eickhoff, Ruben C. Gur, Frank Schneider, Ute Habel, Birgit Derntl Social rewards are processed by the same dopaminergic-mediated brain networks as non-social rewards, suggesting a common representation of subjective value. Individual differences in personality and motivation influence the reinforcing value… Continue reading When opportunity meets motivation: Neural engagement during social approach is linked to high approach motivation
In the eye of the beholder: a qualitative study of mutual obligations and areas of ambiguity in the Hospital-physician relationship
Hospitals and physicians have been working together for years in providing specialized health services. However, Hospital-Physician Relationships are considered lukewarm at best. We build on psychological contract theory to develop an in-depth understanding of how physicians (N=15) and hospital executives (N=15) in Belgium experience and interpret obligations in their working relationship. Our analysis yielded a… Continue reading In the eye of the beholder: a qualitative study of mutual obligations and areas of ambiguity in the Hospital-physician relationship
Rapidly enlarging eyelid lesion
An 82 year woman was referred with a right upper eyelid mass present for at least three months. This was initially diagnosed by her GP as an infected eyelid cyst and treated with antibiotic ointment…. from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RbUkQ3 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader… Continue reading Rapidly enlarging eyelid lesion
Planning of undefined becoming: from poststructuralism towards actor-relational opportunities
From the 1980s onwards, and due to the ongoing complexity and diffuseness in global networked societies, planners have tried to move beyond classic technocratic and/or sociocratic ideas on planning towards new approaches, dealing with the multiplicities and fuzziness of time and space. Innovative ideas have been developed with regard to discursive, collaborative, informal and post-policy… Continue reading Planning of undefined becoming: from poststructuralism towards actor-relational opportunities
MUSE: MUlti-atlas region Segmentation utilizing Ensembles of registration algorithms and parameters, and locally optimal atlas selection
Publication date: 15 February 2016 Source:NeuroImage, Volume 127 Author(s): Jimit Doshi, Guray Erus, Yangming Ou, Susan M. Resnick, Ruben C. Gur, Raquel E. Gur, Theodore D. Satterthwaite, Susan Furth, Christos Davatzikos Atlas-based automated anatomical labeling is a fundamental tool in medical image segmentation, as it defines regions of interest for subsequent analysis of structural and… Continue reading MUSE: MUlti-atlas region Segmentation utilizing Ensembles of registration algorithms and parameters, and locally optimal atlas selection
Dysfunctional long term habituation to exogeneous tinnitus-matched sounds in patients with high tinnitus distress.
*Dysfunctional long term habituation to exogeneous tinnitus-matched sounds in patients with high tinnitus distress.* Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:1967-1970 Authors: Lehser C, Hannemann R, Corona-Strauss FI, Strauss DJ, Haab L, Seidler-Fallbohmer B, Seidler H Abstract During the last years, the demand of accurate diagnostic tools for individualized tinnitus treatment gradually increased. Today several different psychometric instruments for the estimation of the patients degree of decompensation with clinical relevance have emerged. All of these tools are questio... περισσότερα »
Quiet transcranial magnetic stimulation: Status and future directions.
*Quiet transcranial magnetic stimulation: Status and future directions.* Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:226-229 Authors: Peterchev AV, Murphy DL, Goetz SM Abstract A significant limitation of transcranial magnetic stimulation (TMS) is that the magnetic pulse delivery is associated with a loud clicking sound as high as 140 dB resulting from electromagnetic forces. The loud noise significantly impedes both basic research and clinical applications of TMS. It effectively makes TMS less focal since every click activates auditory cortex, brainstem, and other connected r...περισσότερα »
Comparative multivariate analyses of transient otoacoustic emissions and distorsion products in normal and impaired hearing.
*Comparative multivariate analyses of transient otoacoustic emissions and distorsion products in normal and impaired hearing.* Clujul Med. 2015;88(4):500-12 Authors: Stamate MC, Todor N, Cosgarea M Abstract BACKGROUND AND AIM: The clinical utility of otoacoustic emissions as a noninvasive objective test of cochlear function has been long studied. Both transient otoacoustic emissions and distorsion products can be used to identify hearing loss, but to what extent they can be used as predictors for hearing loss is still debated. Most studies agree that multivariate analyses have b... περισσότερα »
Objective pulsatile tinnitus.
*Objective pulsatile tinnitus.* Clin Case Rep. 2015 Dec;3(12):1058-9 Authors: Yacovino DA, Casas P Abstract Tinnitus is the usually unwanted perception of sound, in most cases there is no genuine physical source of sound. Less than 10% of tinnitus patients suffer from pulsatile tinnitus. Objective Pulsatile tinnitus can also be the first indication of dural arteriovenous fistula, so examination for such vascular origin must be performed. PMID: 26733223 [PubMed] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1kOGDIh via IFTTT
A biorobotic model of the human larynx.
*A biorobotic model of the human larynx.* Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:3623-3626 Authors: Manti M, Cianchetti M, Nacci A, Ursino F, Laschi C Abstract This work focuses on a physical model of the human larynx that replicates its main components and functions. The prototype reproduces the multilayer vocal folds and the ab/adduction movements. In particular, the vocal folds prototype is made with soft materials whose mechanical properties have been obtained to be similar to the natural tissue in terms of viscoelasticity. A computational model was used to study flui...περισσότερα »
Voice quality in patients suffering from bipolar disease.
*Voice quality in patients suffering from bipolar disease.* Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:6106-6109 Authors: Guidi A, Schoentgen J, Bertschy G, Gentili C, Landini L, Scilingo EP, Vanello N Abstract People suffering from bipolar disease are more and more common. Such pathology can severely affect patients' lifestyle by wide, and sometimes extreme, mood swings. Biosignals can be very useful to understand this disease. Specifically, speech-related features have been seen to vary in depressed people with respect to healthy subjects. Usually prosodic, spectral and en... περισσότερα »
Can sliding-window correlations reveal dynamic functional connectivity in resting-state fMRI?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Publication date: 15 February 2016 Source:NeuroImage, Volume 127 Author(s): R. Hindriks, M.H. Adhikari, Y. Murayama, M. Ganzetti, D. Mantini, N.K. Logothetis, G. Deco During the last several years, the focus of research on resting-state functional magnetic resonance imaging (fMRI) has shifted from the analysis of functional connectivity averaged over the duration of scanning sessions to […]
Neural correlates of event clusters in past and future thoughts: How the brain integrates specific episodes with autobiographical knowledge
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Publication date: 15 February 2016 Source:NeuroImage, Volume 127 Author(s): Julie Demblon, Mohamed Ali Bahri, Arnaud D’Argembeau When remembering the past or envisioning the future, events often come to mind in organized sequences or stories rather than in isolation from one another. The aim of the present fMRI study was to investigate the neural correlates of […]
When opportunity meets motivation: Neural engagement during social approach is linked to high approach motivation
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Publication date: 15 February 2016 Source:NeuroImage, Volume 127 Author(s): Sina Radke, Eva-Maria Seidel, Simon B. Eickhoff, Ruben C. Gur, Frank Schneider, Ute Habel, Birgit Derntl Social rewards are processed by the same dopaminergic-mediated brain networks as non-social rewards, suggesting a common representation of subjective value. Individual differences in personality and motivation influence the reinforcing value […]
Dietary Guidelines for Americans
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
This Viewpoint summarizes the updated recommendations of the US Department of Health and Human Services’ recently released 2015-2020 Dietary Guidelines for Americans. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Jwpa3e via IFTTT
Effect of sintering on phase evolution AlMgFeCuCrNi4.75 high entropy alloy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Publication date: Available online 7 January 2016 Source:Advanced Powder Technology Author(s): Heena Khanchandani, Priyanka Sharma, Rupesh Kumar, Ornov Maulik, Vinod Kumar Recently, a new metallic alloy design concept has been introduced for developing novel materials for multifunctional applications which are commonly near equiatomic multicomponent alloys having at least five principal elements. These materials have been […]
Direct measurement of molecular mobility and crystallisation of amorphous pharmaceuticals using terahertz spectroscopy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Publication date: Available online 7 January 2016 Source:Advanced Drug Delivery Reviews Author(s): Juraj Sibik, J. Axel Zeitler Despite much effort in the area, no comprehensive understanding of the formation and behaviour of amorphous solids has yet been achieved. This severely limits the industrial application of such materials, including drug delivery where, in principle, amorphous solids […]
Challenges in oral drug delivery of antiretrovirals and the innovative strategies to overcome them
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Publication date: Available online 7 January 2016 Source:Advanced Drug Delivery Reviews Author(s): Alejandro Sosnik, Robin Augustine Development of novel drug delivery systems (DDS) represents a promising opportunity to overcome the various bottlenecks associated with the chronic antiretroviral (ARV) therapy of the human immunodeficiency virus (HIV) infection. Oral drug delivery is the most convenient and simplest […]
Sources of injustice among individuals with persistent pain following musculoskeletal injury
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Abstract Evidence supports the negative impact of perceived injustice on recovery following injury. However, little is known about sources that contribute to injustice perceptions in this context. Therefore, this study systematically investigated sources of injustice following painful musculoskeletal injury. Following completion of the Injustice Experiences Questionnaire (IEQ) and measures of pain, depression, and disability, participants […]
Psychometric Properties of a Brief Instrument to Assess Perceptions of Injustice Associated with Debilitating Health and Mental Health Conditions
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Abstract The present study examined the psychometric properties of a shortened and simplified version of the Injustice Experience Questionnaire (IEQ). The instructional set of the original IEQ was modified to make it better suited to the context of debilitating health and mental health conditions that do not necessarily arise as a result of injury. The […]
Perceived Injustice Predicts Intention to Litigate: Findings from a Spinal Cord Injury Sample
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Abstract The current study examined the association between perceived injustice (assessed by the Injustice Experiences Questionnaire) and intent to litigate in a sample of individuals who had recently suffered a spinal cord injury and were currently on an inpatient rehabilitation unit. Higher perception of injustice was associated with reported interest in litigation. In logistic regression […]
Endoscopic management of orbital tumors
Endoscopic management of orbital tumors: [image: image] Purpose of review: Orbital tumors have been classically approached via external incision. The introduction of endoscopic surgery has revolutionized the management of sinus and skull base disorder. Similarly, endoscopic techniques have been increasingly utilized to access intraorbital tumors located in the medial and inferior orbit with excellent outcomes. The history of the procedure, surgical anatomy of the orbit, patient selection, surgical planning, and the surgical techniques are discussed in this article. Recent findings:... περισσότερα »
Current Opinion in Otolaryngology & Head and Neck Surgery - Current Issue
Editorial introductions [image: image]No abstract available Rhinology: updates on best practice No abstract available New innovations in office-based rhinology [image: image]Purpose of review: Chronic rhinosinusitis (CRS) affects millions of patients worldwide, with significant health and financial implications. There is an immense utilization of resources involved, including prescription medications and surgical interventions. With increased emphasis on sound resource allocation and patient convenience, recent years have witnessed significant expansion in office-based rhinologic proc... περισσότερα »
Peri-implant bone loss clinical and radiographic evaluation around rough neck and microthread implants: a 5-year study
[image: cover.gif?v=1&s=2eb91ab0c0aac4a9489c87d3] Abstract Objective To evaluate marginal bone loss over 5 years around microthreaded implants placed in the maxillary anterior/esthetic zone and immediate restored with non-occlusal loading. Materials and methods Seventy-one implants (with microthreads up to the platform-rough surface body and neck, internal connection and platform switching) were placed in healed bone in the maxillary arches of 30 men and 23 women (mean age 37.85 ± 7.09 years, range 27–60). All subjects had at least 3 mm of soft tissue to allow the establishment...περισσότερα »
Esthetic assessment of immediately restored implants combined with GBR and free connective tissue graft
[image: cover.gif?v=1&s=2eb91ab0c0aac4a9489c87d3] Abstract Aim Esthetic assessment of immediately restored implants combined with GBR and free connective tissue (CT) graft Methods A case–control, retrospective study involving 34 patients treated with maxillary anterior single implants, immediately placed and restored. Clinical and esthetic results were analyzed using standard clinical examination and a comprehensive index, comprising pink esthetic and white esthetic scores (PES/WES). The height of the implant crown and the corresponding height of the contralateral tooth crown w...περισσότερα »
The maintenance of inserted titanium implants: in-vitro evaluation of exposed surfaces cleaned with three different instruments
[image: cover.gif?v=1&s=2eb91ab0c0aac4a9489c87d3] Abstract Objective Changes to titanium implants smooth-surfaces after instrumentation were comparatively analyzed using low-vacuum scanning electron microscopy (LV-SEM) and white-light confocal (WLC) profilometry, to accurately evaluate curved surfaces. Material and methods Sixty titanium implants screwed to their abutments were randomly split into three groups for cleaning treatment with (S) stainless-steel Gracey-curettes, (T) titanium Langer-curettes, and (P) an ultrasonic-device with the probe covered with a plastic-tip. One...περισσότερα »
An open, prospective, non-randomized, controlled, multicentre study to evaluate the clinical outcome of implant treatment in women over 60 years of age with osteoporosis/osteopenia: 1-year results
Abstract Background Osteoporosis has been called a potential risk factor for bone healing around implants. Aim The aim of this multicentre study was to verify the clinical performance of fluoridated implants in the maxilla of subjects with diagnosed systemic primary osteoporosis/osteopenia. Material and Methods Postmenopausal women in need of 2–8 splinted implants in maxilla underwent bone mineral density measurements in the hip and spine, using dual-energy X-ray absorptiometry scans. Based on their T-scores, they were divided into two study groups: Group O (osteoporosis/osteop... περισσότερα »
Correlation between polymerization shrinkage stress and C-factor depends upon cavity compliance
Publication date: Available online 6 January 2016 *Source:*Dental Materials Author(s): Zhengzhi Wang, Martin Y.M. Chiang ObjectivesThe literature reports inconsistent results regarding using configuration factor (C-factor) as an indicator to reflect the generation of polymerization shrinkage stress (PS) from dental restorative composites due to the constraint of cavity configuration. The current study aimed at unraveling the complex effects of C-factor on PS based on analytical and experimental approaches together, such that the reported inconsistency can be explained and a signific... περισσότερα »
Interaction of zirconia primers with yttria-stabilized zirconia surfaces
Publication date: Available online 6 January 2016 *Source:*Dental Materials Author(s): Raphael Pilo, Vassilios Kaitsas, Spiros Zinelis, George Eliades ObjectivesRecently several zirconia primers have been introduced to mediate bonding of dimethacrylate resins to yttria-stabilized zirconia frameworks (Y-TZP). The aim of the study was to evaluate the changes in surface chemistry of Y-TZP frameworks induced by zirconia primer treatments.MethodsPolished Y-TZP discs (Lava, 3M ESPE), ultrasonicated for 10min in ethanol, water-rinsed and air-dried were treated as follows: A: Reference (no ...περισσότερα »
Development of a customized whiteness index for dentistry based on CIELAB color space
Publication date: Available online 6 January 2016 *Source:*Dental Materials Author(s): María del Mar Pérez, Razvan Ghinea, María José Rivas, Ana Yebra, Ana María Ionescu, Rade D. Paravina, Luis Javier Herrera ObjectivesTo develop a customized CIELAB-based whiteness index for dentistry that accurately correlates to perception of tooth whiteness.MethodsFour psychophysical experiments (PE1-4) were conducted by three panels of observers (OP1-3) under diffuse/0° observation/measuring conditions and under typical clinical viewing conditions. Nine whiteness indices (WI, Z%, WIC, WIO, W31, ... περισσότερα »
A resin composite material containing an eugenol derivative for intracanal post cementation and core build-up restoration
Publication date: Available online 5 January 2016 *Source:*Dental Materials Author(s): A. Almaroof, L. Rojo, F. Mannocci, S. Deb ObjectivesTo formulate and evaluate new dual cured resin composite based on the inclusion of eugenyl methacrylate monomer (EgMA) with Bis-GMA/TEGDMA resin systems for intracanal post cementation and core build-up restoration of endodontically treated teeth.MethodsEgMA was synthesized and incorporated at 5% (BTEg5) or 10% (BTEg10) into dual-cure formulations. Curing properties, viscosity, Tg, radiopacity, static and dynamic mechanical properties of the comp...περισσότερα »
Are fluoride releasing dental materials clinically effective on caries control?
Publication date: Available online 6 January 2016 *Source:*Dental Materials Author(s): Jaime Aparecido Cury, Branca Heloisa de Oliveira, Ana Paula Pires dos Santos, Livia Maria Andaló Tenuta Objectives(1) To describe caries lesions development and the role of fluoride in controlling disease progression; (2) to evaluate whether the use of fluoride-releasing pit and fissure sealants, bonding orthodontic agents and restorative materials, in comparison to a non-fluoride releasing material, reduces caries incidence in children or adults, and (3) to discuss how the anti-caries properties ... περισσότερα »
In vivo biofunctionalization of titanium patient-specific implants with nano hydroxyapatite and other nano calcium phosphate coatings: A systematic review
Publication date: Available online 7 January 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Alexander Bral, Maurice Y. Mommaerts ObjectiveTo delineate the best procedures for increasing osseointegration in cranio-maxillo-facial surgery using nano-sized calcium phosphate coatings on titanium patient specific implants.Materials and methodsA multi-database single-reviewer systematic literature review was conducted.ResultsTwenty-eight papers consisting of twenty-five animal studies and three human studies met the selection criteria. The results of existing literature s... περισσότερα »
HNCs
Early death among head and neck cancer patients. Purpose of review: Management of advanced head and neck cancer (HNC) is characterized by high mortality. Furthermore, the treatment involves significant burden to patients and high costs to healthcare systems. Recognizing the risks of early death in patients with a high probability of noncurable disease is important for each individual treatment decision-making. It is thus critical to consider the benefits and side-effects of the planned treatment in relation to the expected survival and to discuss these factors with the patient. Howev... περισσότερα »
Laryngeal cancer in nondrinker nonsmoker young patients
: a distinct pathological entity?. Purpose of review: Laryngeal cancer published literature was reviewed, with emphasis on reporting on young patients (<40 years). With such information, to comment on the evidence or not, that such patients, should they be nondrinkers and nonsmokers, have a differing cause and genetic/molecular profile rather than a spectrum of the classic disease. Recent findings: Head and neck cancer in young patients is documented at a rate of 0.4-3.6%, with laryngeal cancer being identified in less than 2% of all diagnosed head and neck cancer patients overall. H... περισσότερα »
Current Opinion in Otolaryngology & Head and Neck Surgery - Published Ahead-of-Print
Early death among head and neck cancer patients. Purpose of review: Management of advanced head and neck cancer (HNC) is characterized by high mortality. Furthermore, the treatment involves significant burden to patients and high costs to healthcare systems. Recognizing the risks of early death in patients with a high probability of noncurable disease is important for each individual treatment decision-making. It is thus critical to consider the benefits and side-effects of the planned treatment in relation to the expected survival and to discuss these factors with the patient. Howev... περισσότερα »
Paediatric Diagnostic Audiology Testing
Paediatric Diagnostic Audiology Testing in South Africa: With the increased emphasis on the importance of early identification of paediatric hearing loss within developing countries such as South Africa and Nigeria there has been a recognition of the ethical obligation to ensure access to timely diagnostic and intervention services for children identified with hearing loss; regardless of their geographic or socioeconomic status. There are limited studies on diagnosis of paediatric hearing loss in a developing world context. AbstractIntroduction With the increased emphasis on the ... περισσότερα »
Prelingual auditory-perceptual skills as indicators of initial oral language development in deaf children with cochlear implants
Prelingual auditory-perceptual skills as indicators of initial oral language development in deaf children with cochlear implants: to assess when prelingually deaf children with a cochlear implant (CI) achieve the first milestone of oral language, to study the progression of their prelingual auditory skills in the first year after CI and to investigate a possible correlation between such skills and the timing of initial oral language development. AbstractObjectives to assess when prelingually deaf children with a cochlear implant (CI) achieve the first milestone of oral language, ... περισσότερα »
Swallowing dysfunction among patients with laryngeal cleft
Swallowing dysfunction among patients with laryngeal cleft: More than just aspiration?: The Modified Barium Swallow (MBS) is the most widely utilized instrumental assessment of swallowing disorders in children; however, the exact role in the evaluation of laryngeal clefts remains controversial. AbstractBackground The Modified Barium Swallow (MBS) is the most widely utilized instrumental assessment of swallowing disorders in children; however, the exact role in the evaluation of laryngeal clefts remains controversial. Methods This study was an IRB-approved retrospective review on pa... περισσότερα »
Efficacy of Maxillomandibular Advancement Examined with Drug-Induced Sleep Endoscopy and Computational Fluid Dynamics Airflow Modeling
Efficacy of Maxillomandibular Advancement Examined with Drug-Induced Sleep Endoscopy and Computational Fluid Dynamics Airflow Modeling: Objectives To use drug-induced sedation endoscopy (DISE) and computational fluid dynamics (CFD) modeling to study dynamic airway and airflow changes after maxillomandibular advancement (MMA), and how the changes correlate with surgical success based on polysomnography parameters. Study Design Retrospective cohort study. Setting University medical center. Methods DISE was rated with the VOTE (velum, oropharynx, tongue, epiglottis) classification,... περισσότερα »
Intubated ICU Patients Undergoing Tracheotomy
Randomized Controlled Trial Assessing the Feasibility of Shortened Fasts in Intubated ICU Patients Undergoing Tracheotomy: Objective American Society of Anesthesiology guidelines recommend preoperative fasts of 6 hours after light snacks and 8 hours after large meals. These guidelines were designed for healthy patients undergoing elective procedures but are often applied to intubated intensive care unit (ICU) patients. ICU patients undergoing routine procedures may be subjected to unnecessary prolonged fasts. This study tests whether shorter fasts allow for better nutrition delivery...περισσότερα »
Audiometric Outcomes in Pediatric Temporal Bone Trauma
Audiometric Outcomes in Pediatric Temporal Bone Trauma: Objective To characterize pediatric temporal bone trauma, focusing on audiometric outcomes. Study Design Case series with chart review. Setting Tertiary care children’s hospital. Subjects and Methods Cases were reviewed of children (<18 years) presenting over a 3-year period with computed tomography–proven temporal bone fracture and audiology examination. All scans were read by a neuroradiologist and reviewed by a pediatric otolaryngologist. Demographics, fracture pattern, and audiometric data were recorded. Results Fifty... περισσότερα »
Medicolegal Aspects of Iatrogenic Dysphonia and Recurrent Laryngeal Nerve Injury
Medicolegal Aspects of Iatrogenic Dysphonia and Recurrent Laryngeal Nerve Injury: Objective To examine aspects of litigation involving iatrogenic dysphonia and injury to the recurrent laryngeal nerve in the adult population. Study Design Legal database review. Setting Medicolegal judicial system. Subjects and Methods Jury verdicts and settlement reports listing voice impairment or recurrent laryngeal nerve dysfunction as a primary injury in adult patients were identified in the Westlaw Database. Reports were examined for plaintiff demographics, defendant specialty, procedure per... περισσότερα »
Histone Deacetylase 2 in Sudden Sensorineural Hearing Loss Patients in Response to Intratympanic Methylprednisolone Perfusion
Histone Deacetylase 2 in Sudden Sensorineural Hearing Loss Patients in Response to Intratympanic Methylprednisolone Perfusion: Objective To evaluate the expression of histone deacetylase 2 (HDAC2) in peripheral blood mononuclear cells (PBMCs) from patients with sudden sensorineural hearing loss (SSNHL) who were refractory to systemic glucocorticoid treatment and to identify the relationship between the level of HDAC2 and glucocorticoid insensitivity. Study Design Prospective clinical study. Setting This study was conducted in Nanjing Drum Tower Hospital, Nanjing University Medica...περισσότερα »
Smoking Cessation and Electronic Cigarette Use
Smoking Cessation and Electronic Cigarette Use among Head and Neck Cancer Patients: Objectives (1) Investigate electronic cigarette (e-cig) use among head and neck (HN) cancer patients; (2) define quit methods, success, motivations, and barriers to smoking cessation; and (3) determine the impact of e-cig use in smoking cessation. Study Design Cross-sectional study. Setting Tertiary care center. Methods An in-office survey was administered to HN cancer patients ≥19 years of age with past/present tobacco use. Patient demographics were collected. Quit methods, success, and motivat...περισσότερα »
Quantitative Vestibular Labyrinthine Otopathology in Temporal Bones with Vestibular Schwannoma
Quantitative Vestibular Labyrinthine Otopathology in Temporal Bones with Vestibular Schwannoma: Objective Dizziness associated with vestibular schwannoma is usually ascribed to retrolabyrinthine mechanisms. The goal of this study was to determine if quantitative peripheral vestibular (labyrinthine) otopathology was present in a series of patients with vestibular schwannoma. Study Design Comparative human temporal bone study. Setting Otopathology laboratory. Subjects and Methods Temporal bones from 12 subjects with unilateral sporadic vestibular schwannoma were included. Based on...περισσότερα »
Supraclavicular Artery Island Flap and Fasciocutaneous Free Flap
Comparison of Perioperative Outcomes between the Supraclavicular Artery Island Flap and Fasciocutaneous Free Flap: Objective Outcomes of the supraclavicular artery island flap (SCAIF) have not been extensively studied in comparison with free tissue transfer (FTT) flaps for head and neck reconstruction. We hypothesize that the pedicled SCAIF has decreased operating room time, length of stay, time to wound healing of recipient site, complications, and hospital charges as compared with FTT. Study Design Case series with chart review. Setting Tertiary care teaching hospital. Subjects...περισσότερα »
Innate Immune Response of the Laryngeal Mucosa to Endotracheal Intubation
Innate Immune Response of the Pig Laryngeal Mucosa to Endotracheal Intubation: Objective The aim of this study was to measure the effects of endotracheal intubation on innate immune response within *the pig laryngeal mucosa.* Study Design Prospective controlled basic science study. Setting The animal experiments and analyses were conducted at the University of Bristol. Samples and Methods Eighteen pigs, matched at the major histocompatibility complex (MHC), were used in the study. The pigs were divided into 9 pairs. One of each pair (9 pigs in total) was intubated with an endotr... περισσότερα »
Head and Neck Reconstruction with Chimeric Anterolateral Thigh Free Flap
Head and Neck Reconstruction with Chimeric Anterolateral Thigh Free Flap: Indications, Outcomes, and Technical Considerations: Objective Chimeric anterolateral thigh free flaps are composed of multiple skin paddles or muscular components that allow for the reconstruction of complex 3-dimensional defects. We present our experience with the technique and applications for various head and neck defects. Study Design Retrospective chart review. Setting Academic tertiary care center. Subjects and Methods Subjects include 24 consecutive patients undergoing reconstruction with a chimeri... περισσότερα »
Predictors of Nodal Metastasis in Parotid Malignancies
Predictors of Nodal Metastasis in Parotid Malignancies: A National Cancer Data Base Study of 22,653 Patients: Objective (1) To identify predictors of nodal disease in parotid malignancies using various clinical and pathologic variables. (2) To examine the effect of nodal disease on overall survival (OS) in parotid cancers Study Design Retrospective database review. Setting National Cancer Data Base (1998-2012). Subjects and Methods We identified all cases of primary parotid malignancies in the United States between 1998 and 2012 in the National Cancer Data Base. Eight histopatho...περισσότερα »
Increased Expression of FGF19 Contributes to Tumor Progression and Cell Motility of Human Thyroid Cancer
Increased Expression of FGF19 Contributes to Tumor Progression and Cell Motility of Human Thyroid Cancer: Objective Numerous reports indicate a role for aberrant expression of fibroblast growth factor 19 (FGF19) in tumor development and progression, and several drugs have been developed to target it. The aim of this study was to investigate the clinical significance of FGF19 and examine whether it plays any roles in progression of thyroid cancer. Study Design Translation research. Setting Navy General Hospital of Chinese PLA, China. Subjects and Methods Expression patterns of FG...περισσότερα »
Prognostic Indicators for Salvage Surgery of Recurrent Sinonasal Malignancy
Prognostic Indicators for Salvage Surgery of Recurrent Sinonasal Malignancy: Objective Identify prognostic factors after salvage surgery for recurrent sinonasal malignancy (SNM). Study Design Case series with chart review. Setting University of Pittsburgh Medical Center. Subjects Forty-two patients who underwent curative surgery for locally recurrent SNM ± adjuvant therapy from June 5, 2000, to December 19, 2012. Patients without follow-up were excluded. Methods Chart review with established prognostic indicators for primary malignancies. Statistical analysis included Kaplan-M... περισσότερα »
Impact of Microcalcifications on Risk of Malignancy in Thyroid Nodules with Indeterminate or Benign Cytology
Impact of Microcalcifications on Risk of Malignancy in Thyroid Nodules with Indeterminate or Benign Cytology: Objective Adverse sonographic features such as microcalcification may predict increased likelihood of malignant cytology by fine-needle aspiration and, accordingly, increased risk of malignant histology. Our objective was to study the predictive value of microcalcifications and other sonographic features for malignancy among thyroid nodules with benign or indeterminate cytology. Study Design Case series with chart review. Setting Academic teaching hospital. Subjects Pat... περισσότερα »
Utility of Allergy Testing in Patients with Chronic Laryngopharyngeal Symptoms: Is It Allergic Laryngitis?
Utility of Allergy Testing in Patients with Chronic Laryngopharyngeal Symptoms: Is It Allergic Laryngitis?: Objective To determine the utility of allergy evaluation in patients with chronic refractory laryngeal symptoms. Study Design Case series with chart review. Setting Tertiary academic medical center. Subjects All patients who underwent in vitro allergy testing at a single institution from 2006 to 2010, for a total of 998 patients. Methods Charts of patients who underwent in vitro allergy testing were identified. The charts were reviewed for the primary indication for aller... περισσότερα »
A Pediatric Grading Scale for Lingual Tonsil Hypertrophy
A Pediatric Grading Scale for Lingual Tonsil Hypertrophy: Lingual tonsil hypertrophy (LTH) is a common finding for children with residual obstructive sleep apnea (OSA) following an adenotonsillectomy. Secondary to the significant morbidity associated with OSA, identification and treatment of residual OSA are paramount. A dedicated LTH grading scale for children does not exist. The current adult LTH scale is impractical for children. Imaging is not routine for children, since it frequently requires sedation. We present a pediatric LTH grading scale with substantial interrater reliab... περισσότερα »
Paranasal Sinus Balloon Catheter Dilation for Treatment of Chronic Rhinosinusitis
Paranasal Sinus Balloon Catheter Dilation for Treatment of Chronic Rhinosinusitis: A Systematic Review and Meta-analysis: Objective Paranasal sinus balloon catheter dilation (BCD) represents a commonly used tool in the management of chronic rhinosinusitis (CRS) for which the indications, utilization, and outcomes have not been well established. A systematic review and meta-analysis were undertaken to evaluate change in quality of life and sinus opacification following paranasal sinus BCD in the treatment of CRS. Data Sources MEDLINE and EMBASE databases. Review Methods Preferred ... περισσότερα »
Cisplatin-Induced Ototoxicity and the Effects of Intratympanic Diltiazem
Cisplatin-Induced Ototoxicity and the Effects of Intratympanic Diltiazem in a Mouse Model: Objective To evaluate whether the calcium-channel blocker diltiazem has protective effects against cisplatin-induced ototoxicity in a mouse model. Study Design Original basic science in vivo investigation. Setting Academic setting: Otolaryngology–Head and Neck Surgery laboratory at University of Connecticut Health Center. Subjects Thirty-nine female CBA/J mice. Methods Pure tone– or click-evoked auditory brainstem responses (ABRs) were recorded in CBA/J mice to determine auditory threshol... περισσότερα »
Eligibility and Outcomes in Tinnitus Trials
A Systematic Review of Eligibility and Outcomes in Tinnitus Trials: Reassessment of Tinnitus Guideline: Objective To analyze existing tinnitus treatment trials with regard to eligibility criteria, outcome measures, study quality, and external validity and to recognize the effect of patient demographics, symptom duration, severity, and otologic comorbidity on research findings to help practitioners apply them to patient encounters. Data Sources Systematic literature search conducted by an information specialist for development of the American Academy of Otolaryngology—Head and Neck ...περισσότερα »
Head and Neck and Non-Head and Neck Malignant Peripheral Nerve Sheath Tumors
Comparative Analysis of Head and Neck and Non-Head and Neck Malignant Peripheral Nerve Sheath Tumors: Objectives Malignant peripheral nerve sheath tumors (MPNSTs) are a group of tumors that arise from peripheral nerves or from the various elements of the nerve sheath, including Schwann cells and perineural fibroblasts. Head and neck MPNSTs (HN-MPNSTs) are rare, accounting for 8% to 16% of all soft tissue sarcomas. This study analyzes the demographic, clinicopathologic, and survival characteristics of HN-MPNSTs and establishes comparisons with MPNSTs at other body sites (other-MPNSTs... περισσότερα »
FNA has moderate sensitivity and high specificity in differentiating malignant from benign parotid lesions
Sensitivity, Specificity, and Posttest Probability of Parotid Fine-Needle Aspiration: A Systematic Review and Meta-analysis: Objectives (1) To analyze the sensitivity and specificity of fine-needle aspiration (FNA) in distinguishing benign from malignant parotid disease. (2) To determine the anticipated posttest probability of malignancy and probability of nondiagnostic and indeterminate cytology with parotid FNA. Data Sources Independently corroborated computerized searches of PubMed, Embase, and Cochrane Central Register were performed. These were supplemented with manual searche... περισσότερα »
Schooling Relates to Mental Health Problems in Adolescents with Cochlear Implants-Mediation by Hearing and Family Variables.
*Schooling Relates to Mental Health Problems in Adolescents with Cochlear Implants-Mediation by Hearing and Family Variables.* Front Psychol. 2015;6:1889 Authors: Huber M, Pletzer B, Giourgas A, Nickisch A, Kunze S, Illg A Abstract Aim of this multicenter study was to investigate whether schooling relates to mental health problems of adolescents with cochlear implants (CI) and how this relationship is mediated by hearing and family variables. One hundred and forty secondary school students with CI (mean age = 14.7 years, SD = 1.5), their hearing parents and teachers completed the...περισσότερα »
Analysis of incidence and genetic predisposition of preauricular sinus.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Analysis of incidence and genetic predisposition of preauricular sinus.* Int J Pediatr Otorhinolaryngol. 2014 Dec;78(12):2255-7 Authors: An SY, Choi HG, Lee JS, Kim JH, Yoo SW, Park B Abstract OBJECTIVES: To evaluate the incidence of preauricular sinus, the association between preauricular sinus of a parent and their children, and the odds of hearing impairments in patients with preauricular sinus. METHODS: A cross-sectional study was performed using data from the Korea National Health and Nutrition Examination Sur...περισσότερα »
Quantifying spinal gait kinematics using an enhanced optical motion capture approach in adolescent idiopathic scoliosis
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Stefan Schmid, Daniel Studer, Carol-Claudius Hasler, Jacqueline Romkes, William R. Taylor, Silvio Lorenzetti, Reinald Brunner Background and purposeThe pathogenesis of adolescent idiopathic scoliosis (AIS) remains poorly understood. Previous research has indicated possible relationships between kinematics of the spine, pelvis and lower extremities during gait and the progression of AIS, but adequate evidence on spinal kinematics is lacking. The aim of this study was to provide a detailed assessment of spin...περισσότερα »
Does providing real-time augmented feedback affect the performance of repeated lower limb loading to exhaustion?
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Amitabh Gupta, Ryan J. Hilliard, Kurt L. Mudie, Peter J. Clothier IntroductionThis study aimed to determine whether real-time augmented feedback influenced performance of single-leg hopping to volitional exhaustion.MethodsTwenty-seven healthy, male participants performed single-leg hopping (2.2Hz) with (visual and tactile feedback for a target hop height) or without feedback on a force plate. Repeated measures ANOVA were used to determine differences in vertical stiffness (k), duration of flight (tf) and l... περισσότερα »
Long term gait outcomes of surgically treated idiopathic toe walkers
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Mark L. McMulkin, Andi B. Gordon, Bryan J. Tompkins, Paul M. Caskey, Glen O. Baird Toe walking is a common gait deviation which in the absence of a known cause is termed idiopathic toe walking. Surgical treatment in the presence of a triceps surae contracture includes tendo-Achilles or gastrocnemius/soleus recession and has been shown to be effective in improving kinematic outcomes at a one year follow up. The purpose of this study was to assess longer term kinematic and kinetic outcomes of children with ...περισσότερα »
Age-related decline of gait variability in children with attention-deficit/hyperactivity disorder: Support for the maturational delay hypothesis in gait
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Olivia Manicolo, Alexander Grob, Sakari Lemola, Priska Hagmann-von Arx BackgroundPrevious findings showed a tendency toward higher gait variability in children with attention-deficit/hyperactivity disorder (ADHD) compared to controls. This study examined whether gait variability in children with ADHD eventually approaches normality with increasing age (delay hypothesis) or whether these gait alterations represent a persistent deviation from typical development (deviation hypothesis).MethodThis cross-secti...περισσότερα »
The reliability of local dynamic stability in walking while texting and performing an arithmetical problem
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Dennis Hamacher, Daniel Hamacher, Alexander Törpel, Martin Krowicki, Fabian Herold, Lutz Schega In the recent years, local dynamic stability of walking was frequently used to quantify motor control. Particularly, dual-task paradigms are used to assess a shift in gait control strategy to test walking in real life situations. Texting short messages while walking is a common motor-cognitive dual task of daily living. To able to monitor possible intervention effects on motor-cognitive dual-task performance, th... περισσότερα »
Impaired synergic control of posture in Parkinson's patients without postural instability
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Ali Falaki, Xuemei Huang, Mechelle M. Lewis, Mark L. Latash BackgroundPostural instability is one of most disabling motor symptoms in Parkinson's disease. Indices of multi-muscle synergies are new measurements of movement and postural stability.ObjectivesMulti-muscle synergies stabilizing vertical posture were studied in Parkinson's disease patients without clinical symptoms of postural instability (Hoehn-Yahr≤II) and age-matched controls. We tested the hypothesis that both synergy indices during quiet sta... περισσότερα »
Manipulating walking path configuration influences gait variability and six-minute walk test outcomes in older and younger adults
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): C.T. Barnett, M. Bisele, J.S. Jackman, T. Rayne, N.C. Moore, J.L. Spalding, P. Richardson, B. Plummer This study determined whether manipulations to walking path configuration influenced six-minute walk test (6MWT) outcomes and assessed how gait variability changes over the duration of the 6MWT in different walking path configurations. Healthy older (ODR) and younger (YNG) (n=24) adults completed familiarisation trials and five randomly ordered experimental trials of the 6MWT with walking configurations of...περισσότερα »
Quantifying spinal gait kinematics using an enhanced optical motion capture approach in adolescent idiopathic scoliosis
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Stefan Schmid, Daniel Studer, Carol-Claudius Hasler, Jacqueline Romkes, William R. Taylor, Silvio Lorenzetti, Reinald Brunner Background and purposeThe pathogenesis of adolescent idiopathic scoliosis (AIS) remains poorly understood. Previous research has indicated possible relationships between kinematics of the spine, pelvis and lower extremities during gait and the progression of AIS, but adequate evidence on spinal kinematics is lacking. The aim of this study was to provide a detailed assessment of spin...περισσότερα »
Does providing real-time augmented feedback affect the performance of repeated lower limb loading to exhaustion?
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Amitabh Gupta, Ryan J. Hilliard, Kurt L. Mudie, Peter J. Clothier IntroductionThis study aimed to determine whether real-time augmented feedback influenced performance of single-leg hopping to volitional exhaustion.MethodsTwenty-seven healthy, male participants performed single-leg hopping (2.2Hz) with (visual and tactile feedback for a target hop height) or without feedback on a force plate. Repeated measures ANOVA were used to determine differences in vertical stiffness (k), duration of flight (tf) and l... περισσότερα »
Relationship between maximum isometric joint moment and functional task performance in patients with brachial plexus injury: A pilot study
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Dustin L. Crouch, Anthony C. Santago, Johannes F. Plate, Zhongyu Li, Katherine R. Saul We evaluated whether subjects with brachial plexus injury (BPI) adapted their movements to reduce the mechanical demand on their impaired upper extremity. In 6 subjects with unilateral BPI with C5 and C6 involvement, we measured bilateral maximum isometric shoulder and elbow strength, and computed joint kinematics and net muscle-generated joint moments during 7 unimanual functional tasks. Compared to the unimpaired extre... περισσότερα »
Long term gait outcomes of surgically treated idiopathic toe walkers
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Mark L. McMulkin, Andi B. Gordon, Bryan J. Tompkins, Paul M. Caskey, Glen O. Baird Toe walking is a common gait deviation which in the absence of a known cause is termed idiopathic toe walking. Surgical treatment in the presence of a triceps surae contracture includes tendo-Achilles or gastrocnemius/soleus recession and has been shown to be effective in improving kinematic outcomes at a one year follow up. The purpose of this study was to assess longer term kinematic and kinetic outcomes of children with ...περισσότερα »
Parotid Fine-Needle Aspiration
Sensitivity, Specificity, and Posttest Probability of Parotid Fine-Needle Aspiration: A Systematic Review and Meta-analysis: Objectives (1) To analyze the sensitivity and specificity of fine-needle aspiration (FNA) in distinguishing benign from malignant parotid disease. (2) To determine the anticipated posttest probability of malignancy and probability of nondiagnostic and indeterminate cytology with parotid FNA. Data Sources Independently corroborated computerized searches of PubMed, Embase, and Cochrane Central Register were performed. These were supplemented with manual searche... περισσότερα »
Cranial Nerve Stimulation for Obstructive Sleep Apnea
Three-Year Outcomes of Cranial Nerve Stimulation for Obstructive Sleep Apnea: The STAR Trial: Objective To describe the 36-month clinical and polysomnography (PSG) outcomes in an obstructive sleep apnea (OSA) cohort treated with hypoglossal cranial nerve upper airway stimulation (UAS). Study Design A multicenter prospective cohort study. Setting Industry-supported multicenter academic and clinical setting. Subjects Participants (n = 116) at 36 months from a cohort of 126 implanted participants. Methods Participants were enrolled in a prospective phase III trial evaluating the ... περισσότερα »
Triticeous Cartilage CT Imaging Characteristics, Prevalence, Extent, and Distribution of Ossification
Triticeous Cartilage CT Imaging Characteristics, Prevalence, Extent, and Distribution of Ossification: Objective The triticeous cartilage is a small ovoid cartilaginous structure variably present as a component of the laryngeal skeleton. This structure has received scant attention in the literature and has yet to be described adequately on cross-sectional imaging. Study Design and Setting Retrospective study in a tertiary medical center. Subjects and Methods We investigated triticeous cartilage prevalence in a large population utilizing computed tomography images. The cases of all... περισσότερα »
The triticeous cartilage is a small ovoid cartilaginous structure variably present as a component of the laryngeal skeleton
Triticeous Cartilage CT Imaging Characteristics, Prevalence, Extent, and Distribution of Ossification: Objective The triticeous cartilage is a small ovoid cartilaginous structure variably present as a component of the laryngeal skeleton. This structure has received scant attention in the literature and has yet to be described adequately on cross-sectional imaging. Study Design and Setting Retrospective study in a tertiary medical center. Subjects and Methods We investigated triticeous cartilage prevalence in a large population utilizing computed tomography images. The cases of all... περισσότερα »
Spiral Ganglion Cell Nucleus and Nucleolus Count Units
Empirical Derivation of Correction Factors for Human Spiral Ganglion Cell Nucleus and Nucleolus Count Units: Objective Profile count method for estimating cell number in sectioned tissue applies a correction factor for double count (resulting from transection during sectioning) of count units selected to represent the cell. For human spiral ganglion cell counts, we attempted to address apparent confusion between published correction factors for nucleus and nucleolus count units that are identical despite the role of count unit diameter in a commonly used correction factor formula. ... περισσότερα »
Completion Lymph Node Dissection Based on Risk of Nonsentinel Metastasis in Cutaneous Melanoma of the Head and Neck
Completion Lymph Node Dissection Based on Risk of Nonsentinel Metastasis in Cutaneous Melanoma of the Head and Neck: Objective Theoretically, completion lymph node dissection (CNLD) should have the lowest benefit in the absence of nonsentinel lymph node (NSLN) metastases. For this reason, substantial research efforts have attempted to define specific criteria that are associated with a low-enough risk of NSLN positivity so that CLND can be deferred. Our objectives were (1) to identify features associated with low risk of NSLN positivity in sentinel lymph node–positive cutaneous mela...περισσότερα »
The ethics of future trials
The ethics of future trials: qualitative analysis of physicians’ decision making: Background: The decision to conduct a randomized controlled trial (RCT) in a field raises ethical as well as scientific issues. From the clinical equipoise literature, future trials are justifiable if there is ”honest, professional disagreement in the community of expert practitioners as to the preferred treatment”. Empirical data are sparse about how clinicians apply the principles of equipoise to the justification of future RCTs. For example, selective decontamination of the digestive tract (SDD) is ... περισσότερα »
Relationship of cumulative dust exposure dose and cumulative abnormal rate of pulmonary function in coal mixture workers
Publication date: Available online 6 January 2016 *Source:*The Kaohsiung Journal of Medical Sciences Author(s): Qing-Zeng Qian, Xiang-Ke Cao, Qing-Qiang Qian, Fu-Hai Shen, Qian Wang, Hai-Yan Liu, Jun-Wang Tong To investigate the dose-response relationship between cumulative dust exposure (CDE) and cumulative abnormal rate of pulmonary function in coal mixture workers. Three hundred and twenty eight coal mixture workers (exposed group) and 169 nondust-exposed workers (control group) were recruited. Basic information data were collected and pulmonary function tests were performed. Pul...περισσότερα »
Applied Sciences, Vol. 6, Pages 11: Visualizing the Knowledge Domain of Nanoparticle Drug Delivery Technologies: A Scientometric Review
The scientific literature of nanoparticle drug delivery technologies (NDDT) between 2005 and 2014 was reviewed. The visualized co-citation network of its knowledge domain was characterized in terms of thematic concentrations of co-cited references and emerging trends of surging keywords and citations to references through a scientometric review. The combined dataset of 25,171 bibliographic records were constructed through topic search and citation expansion to ensure adequate coverage of the field. While research in gold nanoparticle and magnetic nanoparticle remains the two most ...περισσότερα »
IJERPH, Vol. 13, Pages 110: A Longitudinal Study of Association between Heavy Metals and Itchy Eyes, Coughing in Chronic Cough Patients: Related with Non-Immunoglobulin E Mediated Mechanism
The association between heavy metals exposure and respiratory diseases or allergic sensitization showing high serum immunoglobulin E (IgE) has been suggested. However, previous findings have been inconsistent and the mechanisms responsible remain unclear. We evaluated heavy metal exposure and its association with coughing, itchy eyes in chronic cough patients with different IgE levels. Ninety outpatients in Kanazawa University Hospital were recruited between January–June 2011. Subjects whose total IgE measured by radioimmunosorbent test were asked to record their daily symptoms. W... περισσότερα »
Applied Sciences, Vol. 6, Pages 12: Lamb Wave Interaction with Adhesively Bonded Stiffeners and Disbonds Using 3D Vibrometry
There are many advantages to adhesively bonding stiffeners onto aircraft structures rather than using traditional mechanical fastening methods. However there is a lack of confidence of the structural integrity of adhesively bonded joints over time. Acousto-ultrasonic Lamb waves have shown great potential in structural health monitoring applications in both metallic and composite structures. This paper presents an experimental investigation of the use of acousto-ultrasonic Lamb waves for the monitoring of adhesively bonded joints in metallic structures using 3D scanning laser vibro... περισσότερα »
IJERPH, Vol. 13, Pages 112: Association between UGT1A1 Polymorphism and Risk of Laryngeal Squamous Cell Carcinoma
Laryngeal cancer is one of the largest subgroups of head and neck cancers. In addition to smoking and alcohol consumption, genetic polymorphisms are also risk factors for the development of laryngeal cancer. However, the exact relation between genetic variants and pathogenesis of laryngeal cancer has remained elusive. The aim of this study was to examine UGT1A1*6 (rs4148323 A/G) polymorphisms in 103 patients with laryngeal cancer and 220 controls using the high resolution melting curve (HRM) technique and to explore the association between UGT1A1*6 (rs4148323 A/G) polymorphisms and... περισσότερα »
Applied Sciences, Vol. 6, Pages 14: A Synchrophasor Based Optimal Voltage Control Scheme with Successive Voltage Stability Margin Improvement
This paper proposes an optimal control scheme based on a synchronized phasor (synchrophasor) for power system secondary voltage control. The framework covers voltage stability monitoring and control. Specifically, a voltage stability margin estimation algorithm is developed and built in the newly designed adaptive secondary voltage control (ASVC) method to achieve more reliable and efficient voltage regulation in power systems. This new approach is applied to improve voltage profile across the entire power grid by an optimized plan for VAR (reactive power) sources allocation; ther... περισσότερα »
IJERPH, Vol. 13, Pages 111: Housing Stakeholder Preferences for the “Soft” Features of Sustainable and Healthy Housing Design in the UK
It is widely recognised that the quantity and sustainability of new homes in the UK need to increase. However, it is important that sustainable housing is regarded holistically, and not merely in environmental terms, and incorporates elements that enhance the quality of life, health and well-being of its users. This paper focuses on the "soft" features of sustainable housing, that is, the non-technological components of sustainable housing and neighbourhood design that can impact occupants' health and well-being. Aims of the study are to ascertain the relative level of importance ... περισσότερα »
Energies, Vol. 9, Pages 30: Phase Change Materials-Assisted Heat Flux Reduction: Experiment and Numerical Analysis
Phase change materials (PCM) in the construction industry became attractive because of several interesting attributes, such as thermo-physical parameters, open air atmospheric condition usage, cost and the duty structure requirement. Thermal performance optimization of PCMs in terms of proficient storage of a large amount of heat or cold in a finite volume remains a challenging task. Implementation of PCMs in buildings to achieve thermal comfort for a specific climatic condition in Iraq is our main focus. From this standpoint, the present paper reports the experimental and numeric... περισσότερα »
Energies, Vol. 9, Pages 31: Assessing the Environmental Sustainability of Electricity Generation in Turkey on a Life Cycle Basis
Turkey's electricity mix is dominated by fossil fuels, but the country has ambitious future targets for renewable and nuclear energy. At present, environmental impacts of electricity generation in Turkey are unknown so this paper represents a first attempt to fill this knowledge gap. Taking a life cycle approach, the study considers eleven impacts from electricity generation over the period 1990–2014. All 516 power plants currently operational in Turkey are assessed: lignite, hard coal, natural gas, hydro, onshore wind and geothermal. The results show that the annual impacts from ... περισσότερα »
Energies, Vol. 9, Pages 33: Molecular Level Factors Affecting the Efficiency of Organic Chromophores for p-Type Dye Sensitized Solar Cells
A series of mono- and di-branched donor-π-acceptor charge-separated dyes incorporating triphenylamine as a donor and either Dalton's or benzothiadiazole group as strong acceptors was synthesized and its fundamental properties relevant to the sensitization of nanocrystalline NiO investigated. The dyes exhibited an intense visible absorption band with a strong charge transfer character favorable to NiO sensitization, shifting the electron density from the donor to the acceptor branches. Nevertheless, the computed exciton binding energy is circa twice that of a common literature stan... περισσότερα »
Energies, Vol. 9, Pages 32: Direct and Indirect Impacts of Vegetation on Building Comfort: A Comparative Study of Lawns, Green Walls and Green Roofs
Following development and validation of the SOLENE-microclimat tool, the underlying model was used to compare the impacts of various "greening strategies" on buildings' summer energy consumption and indoor comfort. This study distinguishes between direct and indirect impacts by successively implementing the test strategies on both the studied building and surrounding ones; it also considers insulated vs. non-insulated buildings. Findings indicate that green walls have a direct effect on indoor comfort throughout the entire building, whereas the effect of green roofs is apparently ...περισσότερα »
Chronic hepatitis B infection is not associated with increased risk of vascular mortality while having an association with metabolic syndrome
Abstract This study aimed to assess the association of chronic hepatitis B (CHB) with vascular mortality and metabolic syndrome (MS) using data from a large population-based cohort study in Iran. A total of 12,781 participants (2249 treatment-naïve CHB and 10,532 without CHB) were studied. Logistic regression model was used to assess the association between MS and CHB with adjustment for age, ALT, PLT, alcohol intake, smoking, exercise, and socioeconomic status. MS was defined according to the ATPIII guidelines. Cox proportional hazards model was used to assess the hazard ratios f...περισσότερα »
Occult hepatitis C virus infection among Egyptian hemodialysis patients
Abstract Background Occult Hepatitis C Virus (HCV) infection (OCI) was reported in an apparently disease-free state in the absence of liver disease, anti-HCV and HCV-RNA in the serum. The existing data examining the clinical significance of OCI and its potential as a source of HCV infection among hemodialysis patients are very limited. We examined the presence of OCI among patients on maintenance hemodialysis at Minia Governorate, Egypt; an HCV endemic country. Methods A total of 81 subjects with negative markers for HCV were enrolled. HCV-RNA was tested in PBMCs by real-time PC...περισσότερα »
Seroprevalence of hepatitis E virus infection among dogs in several developed cities in the Guangdong province of China
Abstract HEV, as a zoonotic disease virus, was seldom studied in dogs especially in stray dogs. As previously reported, dog might be an accidental host of HEV for human beings and some risk factors might play an important role in HEV transmission. Thus, we designed this study to evaluate the seroprevalence of HEV infection among dogs in several cities in Guangdong province of China. This surveillance may help us understand risk factors including location, gender, live type and diet habit for HEV transmission. The overall seroprevalence of anti-HEV antibodies in dogs was 19.00%. Pos... περισσότερα »
Remote Sensing, Vol. 8, Pages 44: Extent and Area of Swidden in Montane Mainland Southeast Asia: Estimation by Multi-Step Thresholds with Landsat-8 OLI Data
Information on the distribution, area and extent of swidden agriculture landscape is necessary for implementing the program of Reducing Emissions from Deforestation and Forest Degradation (REDD), biodiversity conservation and local livelihood improvement. To our knowledge, explicit spatial maps and accurate area data on swidden agriculture remain surprisingly lacking. However, this traditional farming practice has been transforming into other profit-driven land use, like tree plantations and permanent cash agriculture. Swidden agriculture is characterized by a rotational and dynam... περισσότερα »
Energies, Vol. 9, Pages 35: A Viable Electrode Material for Use in Microbial Fuel Cells for Tropical Regions
Electrode materials are critical for microbial fuel cells (MFC) since they influence the construction and operational costs. This study introduces a simple and efficient electrode material in the form of palm kernel shell activated carbon (AC) obtained in tropical regions. The novel introduction of this material is also targeted at introducing an inexpensive and durable electrode material, which can be produced in rural communities to improve the viability of MFCs. The maximum voltage and power density obtained (under 1000 Ω load) using an H-shaped MFC with AC as both anode and cat... περισσότερα »
Clinical evaluation for chin augmentation
: literature review and algorithm proposal via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 7 January 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Helena Hotz Arroyo, Isabela Peixoto Olivetti, Leila Freire Rego Lima, José Roberto Parisi Jurado IntroductionThe esthetic balance of the face results from harmonic and symmetrical facial proportions. The literature describes several methods for lower-third facial analysis, but lacks a simple and practical method.ObjectiveTo review the methods of analysis of the ide... περισσότερα »
Energies, Vol. 9, Pages 34: Assessing the Potential of Plug-in Electric Vehicles in Active Distribution Networks
A multi-objective optimization algorithm is proposed in this paper to increase the penetration level of renewable energy sources (RESs) in distribution networks by intelligent management of plug-in electric vehicle (PEV) storage. The proposed algorithm is defined to manage the reverse power flow (PF) from the distribution network to the upstream electrical system. Furthermore, a charging algorithm is proposed within the proposed optimization in order to assure PEV owner's quality of service (QoS). The method uses genetic algorithm (GA) to increase photovoltaic (PV) penetration wit... περισσότερα »
Remote Sensing, Vol. 8, Pages 46: Seasonal Characterization of Solar Radiation Estimates Obtained from a MSG-SEVIRI-Derived Dataset and a RAMS-Based Operational Forecasting System over the Western Mediterranean Coast
Solar radiation is a key factor in the Earth's energy balance and it is used as a crucial input parameter in many disciplines such as ecology, agriculture, solar energy and hydrology. Thus, accurate information of the global downward surface shortwave flux integration into the grid is of significant importance. From the different strategies used for grid integration of the surface solar radiation estimates, satellite-derived and numerical weather prediction forecasts are two interesting alternatives. In the current work, we present a comprehensive evaluation of the global downward... περισσότερα »
Remote Sensing, Vol. 8, Pages 47: Pre-Launch Radiometric Characterization of JPSS-1 VIIRS Thermal Emissive Bands
Pre-launch characterization and calibration of the thermal emissive spectral bands on the Joint Polar Satellite System (JPSS-1) Visible Infrared Imaging Radiometer Suite (VIIRS) is critical to ensure high quality data products for environmental and climate data records post-launch. A comprehensive test program was conducted at the Raytheon El Segundo facility in 2013–2014, including extensive environmental testing. This work is focused on the thermal band radiometric performance and stability, including evaluation of a number of sensor performance metrics and estimation of uncerta... περισσότερα »
Can sliding-window correlations reveal dynamic functional connectivity in resting-state fMRI?
Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): R. Hindriks, M.H. Adhikari, Y. Murayama, M. Ganzetti, D. Mantini, N.K. Logothetis, G. Deco During the last several years, the focus of research on resting-state functional magnetic resonance imaging (fMRI) has shifted from the analysis of functional connectivity averaged over the duration of scanning sessions to the analysis of changes of functional connectivity within sessions. Although several studies have reported the presence of dynamic functional connectivity (dFC), statistical assessment of the resul... περισσότερα »
Neural correlates of event clusters in past and future thoughts: How the brain integrates specific episodes with autobiographical knowledge
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Julie Demblon, Mohamed Ali Bahri, Arnaud D'Argembeau When remembering the past or envisioning the future, events often come to mind in organized sequences or stories rather than in isolation from one another. The aim of the present fMRI study was to investigate the neural correlates of such event clusters. Participants were asked to consider pairs of specific past or future events: in one condition, the two events were part of the same event cluster (i.e., they were thematically and/o...περισσότερα »
When opportunity meets motivation: Neural engagement during social approach is linked to high approach motivation
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Sina Radke, Eva-Maria Seidel, Simon B. Eickhoff, Ruben C. Gur, Frank Schneider, Ute Habel, Birgit Derntl Social rewards are processed by the same dopaminergic-mediated brain networks as non-social rewards, suggesting a common representation of subjective value. Individual differences in personality and motivation influence the reinforcing value of social incentives, but it remains open whether the pursuit of social incentives is analogously supported by the neural reward system when ... περισσότερα »
Acute gastrointestinal vaso-occlusive ischemia in sickle cell disease: CT imaging features and clinical outcome
Abstract Purpose The purpose of this study was to determine the incidence, specific imaging features, and outcome of gastrointestinal vaso-occlusive ischemia (GVOI) in sickle cell patients undergoing CT for acute abdominal pain. Methods This HIPAA-compliant, IRB-approved retrospective study evaluated sickle cell patients with an abdominal pain crisis and acute gastrointestinal abnormalities on CT from 1/2006… Continue reading Acute gastrointestinal vaso-occlusive ischemia in sickle cell disease: CT imaging features and clinical outcome
Cerebral and Cutaneous Involvements of Xanthoma Disseminatum Successfully Treated with an Interleukin-1 Receptor Antagonist: A Case Report and Minireview
A young male presented with panhypopituitarism (including diabetes insipidus) and temporal lobe epilepsy. A histology specimen of cutaneous papules was diagnostic of non-Langerhans histiocytosis. The diagnosis of xanthoma granulomata was considered based on the clinical and brain MRI findings. Brain lesions significantly worsened over time despite radiotherapy until anakinra induced a complete clinical and radiological… Continue reading Cerebral and Cutaneous Involvements of Xanthoma Disseminatum Successfully Treated with an Interleukin-1 Receptor Antagonist: A Case Report and Minir... περισσότερα »
Browsing the Real World using Organic Electronics, Si-Chips, and a Human Touch
Organic electronics have been developed according to an orthodox doctrine advocating «all-printed», «all-organic» and «ultra-low-cost» primarily targeting various e-paper applications. In order to harvest from the great opportunities afforded with organic electronics potentially operating as communication and sensor outposts within existing and future complex communication infrastructures, high-quality computing and communication protocols must be integrated with… Continue reading Browsing the Real World using Organic Electronics, Si-Chips, and a Human Touch
Added value of diffusion-weighted imaging to MR cholangiopancreatography for the diagnosis of bile duct dilatations
Abstract Purpose To investigate the added value of diffusion-weighted imaging (DWI) when used with conventional T2-weighted magnetic resonance (MR) imaging (T2WI) and MR cholangiopancreatography (MRCP) for diagnosing bile duct dilatations. Methods Our institutional review board approved this retrospective study protocol and waived the informed consent requirement. The study included 151 consecutive patients (70 men, 81… Continue reading Added value of diffusion-weighted imaging to MR cholangiopancreatography for the diagnosis of bile duct dilatations
Spanish speakers: find out more about our prostate cancer symposium in March https://t.co/XPDMQbYMSA https://t.co/cAJ7iqN8NK
Spanish speakers: find out more about our prostate cancer symposium in March https://t.co/XPDMQbYMSA https://t.co/cAJ7iqN8NK from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/685074971941584896 via IFTTT
Helicenes—A New Class of Organic Spin Filter
Chiral helicene, a fully conjugated system without stereogenic carbon, can filter spins effectively at room temperature, a consequence of the chiral-induced spin-selectivity effect. The chirality dictates the spin of the electrons transferred through helicene and magnetoresistance devices based on these molecules show antisymmetric magnetoresistance versus H plots. from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1n5ZrV9 via… Continue reading Helicenes—A New Class of Organic Spin Filter
The kinetics and mechanism of photooxygenation of 4prime or minute-diethylamino-3-hydroxyflavone
Photochem. Photobiol. Sci., 2016, Advance Article DOI: 10.1039/C5PP00358J, Paper Zoltan Szakacs, Marton Bojtar, Laszlo Drahos, Dora Hessz, Mihaly Kallay, Tamas Vidoczy, Istvan Bitter, Miklos Kubinyi 4[prime or minute]-Diethylamino-3-hydroxyflavone is oxidized into a salicylic acid derivative under photolysis. The rate constant and the quantum yield of the photooxidation have been determined and – on the basis… Continue reading The kinetics and mechanism of photooxygenation of 4prime or minute-diethylamino-3-hydroxyflavone
Large Pore-Sized Hollow Mesoporous Organosilica for Redox-Responsive Gene Delivery and Synergistic Cancer Chemotherapy
A stability difference-selective bond breakage strategy for the fabrication of large pore-sized hollow mesoporous organosilica nanoparticles (HMONs) is successfully developed. Moreover, surface-functionalized HMONs are successfully constructed to simultaneously deliver P-gp modulator siRNA and anticancer drugs doxorubicin to reverse the multidrug resistance of cancer cells. from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1PLN0XV via IFTTT from #Med… Continue reading Large Pore-Sized Hollow Mesoporous Organosilica for Redox-Responsive Gene Delivery ... περισσότερα »
Dietary Guidelines for Americans
This Viewpoint summarizes the updated recommendations of the US Department of Health and Human Services’ recently released 2015-2020 Dietary Guidelines for Americans. from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1Jwpa3e via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1JZjMAm via… Continue reading Dietary Guidelines for Americans
Dietary Guidelines for Americans
This Viewpoint summarizes the updated recommendations of the US Department of Health and Human Services’ recently released 2015-2020 Dietary Guidelines for Americans. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Jwpa3e via IFTTT
Prevalence, structure and correlates of anxiety-depression in boys with an autism spectrum disorder
Publication date: February–March 2016 *Source:*Research in Developmental Disabilities, Volumes 49–50 Author(s): Vicki Bitsika, Christopher F. Sharpley, Nicholas M. Andronicos, Linda L. Agnew BackgroundComorbidity of anxiety and depression predicts impaired treatment outcomes, poor quality of life and increased suicide risk. No study has reported on a combined measure of anxiety-depression in boys with an Autism Spectrum Disorder.AimsTo explore the prevalence, underlying factor structure and relationships between anxiety-depression, physiological stress and symptoms of Autism Spectru... περισσότερα »
The three-dimensional volumetric assessment of the effect of decompression on large mandibular odontogenic cystic lesions
Publication date: Available online 6 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Fatih Asutay, Yusuf Atalay, Ozan Turamanlar, Erdal Horata, Muammer Çağrı Burdurlu PurposeThe primary approach to large cystic lesions is still controversial. The aims of the present study were to assess the effects of decompression before the enucleation protocol for the treatment of large cystic lesions and to compare the reduction rate of keratocystic odontogenic tumour, ameloblastoma and dentigerous cysts at specific times (preoperatively and at 6 months).MethodsThe stu...περισσότερα »
Threonine Aspartase1: An unexplored protease with relevance for oral oncology?
Proteases are involved in numerous pathobiological processes in oral cancer. Due to disappointing results with metalloproteinase inhibitors new protease targets need to be explored. The protease Threonine Aspartase1 (Taspase1) is critically involved in tumour promotion and, interestingly, has first been described to be overexpressed in head and neck squamous cell carcinoma (HNSCC). However, our knowledge on how the protease contributes to oral malignancies is still incomplete. In addition, no effective inhibitors for this enzyme are available so far, hampering the assessment of it...περισσότερα »
Postoperation of cervical cancer with intestine metastasis: a case report and literature review
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Cervical cancer can infiltrate locally and directly spread to adjacent organs including the vagina, peritoneum, urinary bladder, ureters, rectum, and paracervical tissue, but the intestine metastasis from cerv… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mIbbwA via IFTTT
Clinicopathological characteristics of unicentric retroperitoneal Castleman’s disease: a study of 14 cases
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The objectives of this study are to investigate the clinicopathological characteristics and prognosis analysis of unicentric retroperitoneal Castleman’s disease (CD), and to improve the level of diagnosis and … from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PgLs5y via IFTTT
Morphometric analysis of young petiole galls on the narrow-leaf cottonwood, Populus angustifolia , by the sugarbeet root aphid, Pemphigus betae
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract An insect-induced gall is a highly specialized structure resulting from atypical development of plant tissue induced by a reaction to the presence and activity of an insect. The insect induces a differentiation of tissues with features and functions of an ectopic organ, providing nutrition and protection to the galling insect from natural enemies and […]
Therapie der medikamentensensiblen Tuberkulose
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Risiken & Nebenwirkung Zunahme der Erregerresistenz und ein großes menschliches ‚Reservoir‘ latent tuberkulöser Infektionen: Tuberkulose ist und bleibt eine der bedrohlichsten Infektionskrankheiten überhaupt. Unser Schwerpunkt informiert Sie über gesicherte Therapiemaßnahmen und Nebenwirkungen. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OcTzAn via IFTTT
Effect of dietary nitrate supplementation on metabolic rate during rest and exercise in human: a systematic review and a meta-analysis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 7 January 2016 Source:Nitric Oxide Author(s): Mehdi Pawlak-Chaouch, Julien Boissière, François X. Gamelin, Grégory Cuvelier, Serge Berthoin, Julien Aucouturier BackgroundRecent randomized controlled trials have suggested that dietary nitrate (NO3-), found in beetroot and other vegetables, and inorganic NO3- salts decrease metabolic rate under resting and exercise conditions.ObjectiveOur aim was therefore to […]
Mucus extravasation phenomenon
Epidemiological survey of mucus extravasation phenomenon at an oral pathology referral center during a 43 year period via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 6 January 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Thâmara Manoela Marinho Bezerra, Bárbara Vanessa de Brito Monteiro, Águida Cristina Gomes Henriques, Marianne de Vasconcelos Carvalho, Cassiano Francisco Weege Nonaka, Márcia Cristina da Costa Miguel IntroductionMucoceles are common benign pseudocystic lesions of the oral cavity; their main ... περισσότερα »
Anomalous Experiences, Trauma, and Symbolization Processes at the Frontiers between Psychoanalysis and Cognitive Neurosciences.
*Anomalous Experiences, Trauma, and Symbolization Processes at the Frontiers between Psychoanalysis and Cognitive Neurosciences.* Front Psychol. 2015;6:1926 Authors: Rabeyron T, Loose T Abstract Anomalous or exceptional experiences are uncommon experiences which are usually interpreted as being paranormal by those who report them. These experiences have long remained difficult to explain, but current progress in cognitive neuroscience and psychoanalysis sheds light on the contexts in which they emerge, as well as on their underlying processes. Following a brief description of th... περισσότερα »
Robust supervised segmentation of neuropathology whole-slide microscopy images.
*Robust supervised segmentation of neuropathology whole-slide microscopy images.* Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:3851-3854 Authors: Vandenberghe ME, Balbastre Y, Souedet N, Herard AS, Dhenain M, Frouin F, Delzescaux T Abstract Alzheimer's disease is characterized by brain pathological aggregates such as Aβ plaques and neurofibrillary tangles which trigger neuroinflammation and participate to neuronal loss. Quantification of these pathological markers on histological sections is widely performed to study the disease and to evaluate new therapies. However, segmenta... περισσότερα »
A Clinical, Neuropathological and Genetic Study of Homozygous A467T POLG-Related Mitochondrial Disease.
*A Clinical, Neuropathological and Genetic Study of Homozygous A467T POLG-Related Mitochondrial Disease.* PLoS One. 2016;11(1):e0145500 Authors: Rajakulendran S, Pitceathly RD, Taanman JW, Costello H, Sweeney MG, Woodward CE, Jaunmuktane Z, Holton JL, Jacques TS, Harding BN, Fratter C, Hanna MG, Rahman S Abstract Mutations in the nuclear gene POLG (encoding the catalytic subunit of DNA polymerase gamma) are an important cause of mitochondrial disease. The most common POLG mutation, A467T, appears to exhibit considerable phenotypic heterogeneity. The mechanism by which this singl... περισσότερα »
Limited Unfolded Protein Response and Inflammation in Neuroserpinopathy.
*Limited Unfolded Protein Response and Inflammation in Neuroserpinopathy.* J Neuropathol Exp Neurol. 2016 Jan 4; Authors: López-González I, Pérez-Mediavilla A, Zamarbide M, Carmona M, Torrejón Escribano B, Glatzel M, Galliciotti G, Ferrer I Abstract Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a rare disease characterized by the deposition of multiple intracytoplasmic neuronal inclusions that contain mutated neuroserpin. Tg-Syracuse (Tg-Syr) mice express Ser49Pro mutated neuroserpin and develop clinical and neuropathological features of human FENIB. We use...περισσότερα »
SOX11 identified by target gene evaluation of miRNAs differentially expressed in focal and non-focal brain tissue of therapy-resistant epilepsy patients.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *SOX11 identified by target gene evaluation of miRNAs differentially expressed in focal and non-focal brain tissue of therapy-resistant epilepsy patients.* Neurobiol Dis. 2015 May;77:127-40 Authors: Haenisch S, Zhao Y, Chhibber A, Kaiboriboon K, Do LV, Vogelgesang S, Barbaro NM, Alldredge BK, Lowenstein DH, Cascorbi I, Kroetz DL Abstract MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally control the expression of their target genes via RNA interference. There is increasing evidence that expre...περισσότερα »
An mHealth system for toxicity monitoring of paediatric oncological patients using Near Field Communication technology.
*An mHealth system for toxicity monitoring of paediatric oncological patients using Near Field Communication technology.* Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:6848-6851 Authors: Duregger K, Hayn D, Morak J, Ladenstein R, Schreier G Abstract Home-based monitoring might be useful to reduce the burden of long-lasting oncological treatment for children. Current telemonitoring applications focus on chronic diseases or elderly people. Based on the workflow for different stakeholders and the identification of parameters important in paediatric oncology, we developed a prototyp... περισσότερα »
Targeting the Warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrest.
*Targeting the Warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrest.* Oncotarget. 2015 Dec 30; Authors: Capello M, Ferri-Borgogno S, Riganti C, Chattaragada MS, Principe M, Roux C, Zhou W, Petricoin EF, Cappello P, Novelli F Abstract In the last 5 years, novel knowledge on tumor metabolism has been revealed with the identification of critical factors that fuel tumors. Alpha-enolase (ENO1) is commonly over-expressed in tumors and is a clinically relevant candidate molecular target for immunotherapy. Here, we silenced ENO...περισσότερα »
Click chemistry, 3D-printing, and omics: the future of drug development.
*Click chemistry, 3D-printing, and omics: the future of drug development.* Oncotarget. 2015 Dec 29; Authors: Kurzrock R, Stewart DJ Abstract Genomics is a disruptive technology, having revealed that cancers are tremendously complex and differ from patient to patient. Therefore, conventional treatment approaches fit poorly with genomic reality. Furthermore, it is likely that this type of complexity will also be observed in other illnesses. Precision medicine has been posited as a way to better target disease-related aberrations, but developing drugs and tailoring therapy to each ... περισσότερα »
The role of dental stem cells in regeneration.
*The role of dental stem cells in regeneration.* Clujul Med. 2015;88(4):479-82 Authors: Maxim MA, Soritau O, Baciut M, Bran S, Baciut G Abstract Mesenchymal stem cells (MSCs) are adult stem cells that have the capacity of rising multiple cell types. A rich source of mesenchymal stem cells is represented by the dental tissues: the periodontal ligament, the dental pulp, the apical papilla, the dental follicle and the deciduous teeth. The aim of this review is to characterize the main dental- derived mesenchymal stem cell population, and to show their important role in tissue regen... περισσότερα »
Diagnostic performance and safety of NMK36 (trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid)-PET/CT in primary prostate cancer: multicenter Phase IIb clinical trial.
*Diagnostic performance and safety of NMK36 (trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid)-PET/CT in primary prostate cancer: multicenter Phase IIb clinical trial.* Jpn J Clin Oncol. 2016 Jan 4; Authors: Suzuki H, Inoue Y, Fujimoto H, Yonese J, Tanabe K, Fukasawa S, Inoue T, Saito S, Ueno M, Otaka A Abstract OBJECTIVE: We performed a multicenter Phase IIb clinical trial of NMK36, a novel amino acid analog for positron emission tomography containing trans-1-amino-3-[(18)F]fluorocyclobutanecarboxylic acid, to evaluate its safety and diagnostic performance for primary pros... περισσότερα »
Evaluation of serum markers in the LRF CLL4 trial: β2m but not serum free light chains, is an independent marker of overall survival.
*Evaluation of serum markers in the LRF CLL4 trial: β2m but not serum free light chains, is an independent marker of overall survival.* Leuk Lymphoma. 2016 Jan 6;:1-31 Authors: Pratt G, Thomas P, Marden N, Alexander D, Davis Z, Hussey D, Parry H, Harding S, Catovsky D, Begley J, Oscier D Abstract Chronic lymphocytic leukaemia (CLL) is characterised by heterogeneous clinical behaviour and there is a need for improved biomarkers. The current study evaluated the prognostic significance of serum free light chains (sFLC, kappa and lambda) and other serum markers (β2M, serum thymidine ...περισσότερα »
Rehabilitation following cerebral anoxia: An assessment of 27 patients.
*Rehabilitation following cerebral anoxia: An assessment of 27 patients.* Brain Inj. 2016 Jan 6;:1-9 Authors: Tazopoulou E, Miljkovitch R, Truelle JL, Schnitzler A, Onillon M, Zucco T, Hawthorne G, Montreuil M Abstract OBJECTIVES: (1) To evaluate cognitive and emotional impairments, disability and quality-of-life for adults with cerebral anoxia institutionalized in residential care facilities. (2) To evaluate the efficacy of medication, psychotherapy, support group and therapeutic activities. METHODS: Twenty-seven persons with cerebral anoxia were recruited, on average 8 years po... περισσότερα »
Feasibility and usability of a wearable orthotic for stroke survivors with hand impairment.
*Feasibility and usability of a wearable orthotic for stroke survivors with hand impairment.* Disabil Rehabil Assist Technol. 2016 Jan 6;:1-9 Authors: Lakshminarayanan K, Wang F, Webster JG, Seo NJ Abstract PURPOSE: The concept of a vibrating wristband, to improve dextrous hand function of stroke survivors, was recently proposed with clinical results and is referred to as 'TheraBracelet' in this paper. The purpose of this study was to demonstrate feasibility of a portable, wearable TheraBracelet, and to apply usability evaluation techniques to assess potential demands of TheraBr... περισσότερα »
The psychometric properties of an Arabic numeric pain rating scale for measuring osteoarthritis knee pain.
*The psychometric properties of an Arabic numeric pain rating scale for measuring osteoarthritis knee pain.* Disabil Rehabil. 2016 Jan 6;:1-6 Authors: Alghadir AH, Anwer S, Iqbal ZA Abstract Purpose The aims of this study were to translate the numeric rating scale (NRS) into Arabic and to evaluate the test-retest reliability and convergent validity of an Arabic Numeric Pain Rating Scale (ANPRS) for measuring pain in osteoarthritis (OA) of the knee. Methods The English version of the NRS was translated into Arabic as per the translation process guidelines for patient-rated outcom... περισσότερα »
Coping strategies used by traumatic spinal cord injury patients in Sri Lanka: a focus group study.
*Coping strategies used by traumatic spinal cord injury patients in Sri Lanka: a focus group study.* Disabil Rehabil. 2016 Jan 5;:1-8 Authors: Arya S, Xue S, Embuldeniya A, Narammalage H, da Silva T, Williams S, Ravindran A Abstract PURPOSE: Psychosocial consequences of traumatic spinal cord injury (SCI) have been well documented in Western populations, but there is no published literature on such incidence in the Sri Lankan population. The purpose of this study was to explore the psychosocial impact of SCI in a Sri Lankan population and to examine this population's coping mecha...περισσότερα »
A qualitative exploration of self-reported unmet need one year after stroke.
*A qualitative exploration of self-reported unmet need one year after stroke.* Disabil Rehabil. 2016 Jan 5;:1-8 Authors: Shannon RL, Forster A, Hawkins RJ Abstract PURPOSE: Stroke survivors consistently report longer-term problems after stroke, suggesting their needs are not being met. We developed a questionnaire to identify stroke-survivor unmet needs. Preliminary questionnaire testing showed that despite residual impairment, nearly one third of respondents reported no/low unmet need. This qualitative study aims to gain insight into why stroke survivors report low/no unmet nee... περισσότερα »
Validity and everyday clinical applicability of lumbar muscle fatigue assessment methods in patients with chronic non-specific low back pain: a systematic review.
*Validity and everyday clinical applicability of lumbar muscle fatigue assessment methods in patients with chronic non-specific low back pain: a systematic review.* Disabil Rehabil. 2016 Jan 5;:1-13 Authors: Villafañe JH, Gobbo M, Peranzoni M, Naik G, Imperio G, Cleland JA, Negrini S Abstract PURPOSE: This systematic literature review aimed at examining the validity and applicability in everyday clinical rehabilitation practise of methods for the assessment of back muscle fatiguability in patients with chronic non-specific low back pain (CNSLBP). METHODS: Extensive research was ...περισσότερα »
Movement changes due to hemiplegia in stroke survivors: a hermeneutic phenomenological study.
*Movement changes due to hemiplegia in stroke survivors: a hermeneutic phenomenological study.* Disabil Rehabil. 2016 Jan 5;:1-14 Authors: Takashima R, Murata W, Saeki K Abstract PURPOSE: Meanings of movement for stroke survivors could give therapists significant insights, especially during maintenance phase. The purpose of this study was to examine how post-stroke users of a long-term elderly care facility had experienced changes in movement resulting from hemiplegia. METHOD: The participants of this study were 18 stroke survivors using a long-term elderly care facility. Based o...περισσότερα »
Impact of surgical staging on prognosis in patients with borderline ovarian tumours: A meta-analysis.
*Impact of surgical staging on prognosis in patients with borderline ovarian tumours: A meta-analysis.* Eur J Cancer. 2015 Dec 28;54:84-95 Authors: Shim SH, Kim SN, Jung PS, Dong M, Kim JE, Lee SJ Abstract BACKGROUND: To quantify the effect of complete surgical staging (CSS) on prognosis in borderline ovarian tumour (BOT) patients through a meta-analysis. METHODS: We systematically reviewed published studies comparing CSS with incomplete surgical staging (ISS) in BOT patients through April 2015. End-points were recurrence and mortality rates. Study design features that possibly ...περισσότερα »
Genomic determinants of somatic copy number alterations across human cancers.
*Genomic determinants of somatic copy number alterations across human cancers.* Hum Mol Genet. 2016 Jan 4; Authors: Zhang Y, Xu H, Frishman D Abstract Somatic copy number alterations (SCNAs) play an important role in carcinogenesis. However, the impact of genomic architecture on the global patterns of SCNAs in cancer genomes remains elusive. In this work we conducted multiple linear regression (MLR) analyses of the pooled SCNA data from The Cancer Genome Atlas Pan-Cancer project. We performed MLR analyses for 11 individual cancer types and three different kinds of SCNAs - ampli...περισσότερα »
Rare solitary fibrous tumor of the stomach: A case report.
*Rare solitary fibrous tumor of the stomach: A case report.* Vojnosanit Pregl. 2015 Nov;72(11):1035-8 Authors: Bosković T, Zivojinov M, Sabo JI, Budakov Z, Veljković R, Zivojinov S Abstract INTRODUCTION: Solitary fibrous tumors are rare soft tissue tumors of submesothelial origin and variable malignant potential. The most common localization is pleural, whereas only 0.6% are of extrapleural localization. Solitary fibrous tumor of the peritoneum, especially of gastric serosa is an extremely rare form of this tumor. CASE REPORT: We presented a 65-year-old female patient with solita... περισσότερα »
Surgical Outcomes in a Large, Clinical, Low-Dose Computed Tomographic Lung Cancer Screening Program.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Surgical Outcomes in a Large, Clinical, Low-Dose Computed Tomographic Lung Cancer Screening Program.* Ann Thorac Surg. 2015 Oct;100(4):1218-23 Authors: Walker BL, Williamson C, Regis SM, McKee AB, D'Agostino RS, Hesketh PJ, Lamb CR, Flacke S, Wald C, McKee BJ Abstract BACKGROUND: Lung cancer screening with low-dose computed tomography is proven to reduce lung cancer mortality among high-risk patients. However, critics raise concern over the potential for unnecessary surgical procedures performed for benign diseas... περισσότερα »
Malignant tumors of the temporal bone
– our experience via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 7 January 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Ana Pereira da Silva, Eduardo Breda, Eurico Monteiro IntroductionMalignant tumors of the temporal bone are rare, with an estimated incidence of about 0.8–1.0 per 1,000,000 inhabitants per year. The vast majority of these tumors are squamous cell carcinomas and their treatment is eminently surgical.ObjectiveThis study is an attempt at systematizing the forms of clinical presentation, the th...περισσότερα »
Use of Conchal Cartilages for Laryngotracheal Stenosis
Use of Conchal Cartilages for Laryngotracheal Stenosis: Experiences at a Tertiary Care Hospital of Eastern India: AbstractTo describe the experience of anterior cricotracheal split with insertion of conchal cartilage graft in the treatment of subglottic and tracheal stenosis at a tertiary care hospital of eastern India. Six patients were included in the study, in the age group of 20–48 years. Out of which five patients were successfully decannulated after 3 months of laryngotracheal reconstruction with help of conchal cartilage. One case was undergone resection anastomosis after fa... περισσότερα »
ENT and airways in the emergency department
ENT and airways in the emergency department: national survey of junior doctors' knowledge and skills: Research Articles K L Whitcroft, B Moss, A Mcrae The Journal of Laryngology Otology, FirstView Article(s) Main ArticleENT and airways in the emergency department: national survey of junior doctors' knowledge and skillsK L Whitcrofta1 c1, B Mossa2 and A Mcrae a1 a1 ENT Department, Lincoln County Hospital, UK a2 University of Nottingham Medical School, Queen's Medical Centre, UK Abstract Background: Given the urgent nature of ENT emergencies, appropriate knowledge is required amongst...περισσότερα »
Tracheal agenesis
Tracheal agenesis, a frightening scenario: Rapid Communication H Mohammed, K West, J Bewick, M Wickstead The Journal of Laryngology Otology, FirstView Article(s) Clinical RecordTracheal agenesis, a frightening scenarioH Mohammeda1 c1, K Westa1, J Bewicka1 and M Wicksteada1 a1 ENT Department, Norfolk and Norwich University Hospital, Norwich, UK Abstract Objective: This paper discusses three cases of tracheal agenesis that presented within a six-week period to the Norfolk and Norwich University Hospital. By reviewing the available literature on tracheal agenesis, the report aims to ... περισσότερα »
Reconciling the log-linear and non-log-linear nature of the TSH-free T4 relationship: intra-individual analysis of a large population.
*Reconciling the log-linear and non-log-linear nature of the TSH-free T4 relationship: intra-individual analysis of a large population.* J Clin Endocrinol Metab. 2016 Jan 6;:jc20154011 Authors: Rothacker KM, Brown SJ, Hadlow NC, Wardrop R, Walsh JP Abstract CONTEXT: The TSH-T4 relationship was thought to be inverse log-linear, but recent cross-sectional studies report a complex, non-linear relationship; large, intra-individual studies are lacking. OBJECTIVE: To analyze the TSH-free T4 relationship within individuals. METHODS: We analyzed data from 13 379 patients, each with 6 or mo...περισσότερα »
POLYMORPHISM rs2274911 OF GPRC6A AS A NOVEL RISK FACTOR FOR TESTIS FAILURE.
*POLYMORPHISM rs2274911 OF GPRC6A AS A NOVEL RISK FACTOR FOR TESTIS FAILURE.* J Clin Endocrinol Metab. 2016 Jan 6;:jc20153967 Authors: Toni L, Nisio AD, Speltra E, Rocca MS, Ghezzi M, Zuccarello D, Turiaco N, Ferlin A, Foresta C Abstract CONTEXT: The G protein-coupled receptor GPRC6A is an emerging effector with multiple endocrine roles, including stimulation of testosterone production from the testis. Recently, two men with an inactivating mutation (F464Y) of GPRC6A have been identified and they showed primary testicular failure and deranged spermatogenesis. Furthermore, one of... περισσότερα »
A Novel Thyrotropin-Releasing Hormone Receptor Missense Mutation (P81R) in Central Congenital Hypothyroidism.
*A Novel Thyrotropin-Releasing Hormone Receptor Missense Mutation (P81R) in Central Congenital Hypothyroidism.* J Clin Endocrinol Metab. 2016 Jan 6;:jc20153916 Authors: Koulouri O, Nicholas AK, Schoenmakers E, Mokrosinski J, Lane F, Cole T, Kirk J, Farooqi IS, Chatterjee VK, Gurnell M, Schoenmakers N Abstract CONTEXT: Isolated central congenital hypothyroidism (CCH) is rare and evades diagnosis on thyroid stimulating hormone (TSH)-based congenital hypothyroidism (CH) screening programmes in the UK. Accordingly, genetic ascertainment facilitates diagnosis and treatment of familial...περισσότερα »
Report on Racial Disparities in Hospitalized Patients with Hyperglycemia and Diabetes.
*Report on Racial Disparities in Hospitalized Patients with Hyperglycemia and Diabetes.* J Clin Endocrinol Metab. 2016 Jan 6;:jc20153220 Authors: Fayfman M, Vellanki P, Alexopoulos AS, Buehler L, Zhao L, Smiley D, Haw S, Weaver J, Pasquel FJ, Umpierrez GE Abstract CONTEXT: A higher prevalence of diabetes-related complications is reported in minority populations; however, it is not known if there are racial disparities in diabetes care and outcomes in hospitalized patients. OBJECTIVE: To determine the association between hyperglycemia, in patients with and without DM (non-DM), and...περισσότερα »
Search for a New Editor.
*Search for a New Editor.* Radiology. 2016 Jan 6; Authors: Rao VM PMID: 26735772 [PubMed - as supplied by publisher] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1ZPrUg4 via IFTTT
Challenges of thyroid cancer management in amiodarone-treated patients: a case report.
*Challenges of thyroid cancer management in amiodarone-treated patients: a case report.* Clujul Med. 2015;88(4):550-4 Authors: Petrulea MS, Lencu C, Piciu D, Lisencu CI, Georgescu CE Abstract Thyroid carcinoma (TC) is the most common endocrine malignancy. Although the overall prognosis for patients with TC is good, up to 20-30% of patients have recurrent or persistent disease after conventional therapy by surgical resection and radioactive iodine (RAI). Amiodarone is a highly efficient anti-arrhythmic drug with a very long half-life, so it may interfere with RAI many months afte... περισσότερα »
Effect of intranasal steroids on rhinosinusitis after radiotherapy for nasopharyngeal carcinoma: clinical study
Effect of intranasal steroids on rhinosinusitis after radiotherapy for nasopharyngeal carcinoma: clinical study: Research Articles S Feng, Y Fan, Z Liang, G Yang, Z Liao, L Guo The Journal of Laryngology Otology, FirstView Article(s) Main ArticleEffect of intranasal steroids on rhinosinusitis after radiotherapy for nasopharyngeal carcinoma: clinical studyS Fenga1, Y Fana1 c1, Z Lianga2, G Yanga2, Z Liaoa1 and L Guoa1 a1 Department of Otolaryngology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China a2 Department of Radiation Oncology, Fifth Affiliated Hospital of Su... περισσότερα »
Voice pathology classification based on High-Speed Videoendoscopy.
*Voice pathology classification based on High-Speed Videoendoscopy.* Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:735-738 Authors: Panek D, Skalski A, Zielinski T, Deliyski DD Abstract This work presents a method for automatical and objective classification of patients with healthy and pathological vocal fold vibration impairments using High-Speed Videoendoscopy of the larynx. We used an image segmentation and extraction of a novel set of numerical parameters describing the spatio-temporal dynamics of vocal folds to classification according to the normal and pathological cases ... περισσότερα »
Large Cell Neuroendocrine Carcinoma of the Head and Neck: A Clinicopathologic Series of 10 Cases With an Emphasis on HPV Status.
*Large Cell Neuroendocrine Carcinoma of the Head and Neck: A Clinicopathologic Series of 10 Cases With an Emphasis on HPV Status.* Am J Surg Pathol. 2016 Jan 5; Authors: Thompson ED, Stelow EB, Mills SE, Westra WH, Bishop JA Abstract Large cell neuroendocrine carcinoma (LCNEC) is a high-grade neuroendocrine neoplasm first described in the lung and subsequently well documented in many other anatomic sites. It has only recently been recognized that LCNEC can also occasionally arise in the head and neck. The role of human papillomavirus (HPV), which is associated with some small cel... περισσότερα »
Secondhand Smoking and the Risk of Esophageal Squamous Cell Carcinoma in a High Incidence Region, Kashmir, India: A Case-control-observational Study.
*Secondhand Smoking and the Risk of Esophageal Squamous Cell Carcinoma in a High Incidence Region, Kashmir, India: A Case-control-observational Study.* Medicine (Baltimore). 2016 Jan;95(1):e2340 Authors: Rafiq R, Shah IA, Bhat GA, Lone MM, Islami F, Boffetta P, Dar NA Abstract Studies have associated secondhand smoking (SHS) with cancers of the lung, larynx, and pharynx. Only a few studies have examined the association between SHS and esophageal squamous cell carcinoma (ESCC) and the findings are inconclusive. We aimed to investigate the association between SHS and risk of ESCC i... περισσότερα »
The Role of the Paratrigeminal Nucleus in Vagal Afferent Evoked Respiratory Reflexes: A Neuroanatomical and Functional Study in Guinea Pigs.
*The Role of the Paratrigeminal Nucleus in Vagal Afferent Evoked Respiratory Reflexes: A Neuroanatomical and Functional Study in Guinea Pigs.* Front Physiol. 2015;6:378 Authors: Driessen AK, Farrell MJ, Mazzone SB, McGovern AE Abstract The respiratory tree receives sensory innervation from the jugular and nodose vagal sensory ganglia. Neurons of these ganglia are derived from embryologically distinct origins and as such demonstrate differing molecular, neurochemical and physiological phenotypes. Furthermore, whereas nodose afferent neurons project to the nucleus of the solitary ...περισσότερα »
Aberrant laryngeal location of Onchocerca lupi in a dog.
*Aberrant laryngeal location of Onchocerca lupi in a dog.* Parasitol Int. 2015 Dec 27; Authors: Alho AM, Cruz L, Coelho A, Martinho F, Mansinho M, Annoscia G, Lia RP, Giannelli A, Otranto D, de Carvalho LM Abstract Onchocerca lupi (Spirurida, Onchocercidae) is an emerging vector-borne helminth that causes nodular lesions associated with acute or chronic ocular disease in dogs and cats. Since its first description in dogs in 1991, this zoonotic filarioid has been increasingly reported in Europe and the United States. An 8-year-old outdoor mixed-breed female dog from the Algarve (... περισσότερα »
Different spectral hounsfield unit curve and high-energy virtual monochromatic image characteristics of squamous cell carcinoma compared with nonossified thyroid cartilage.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Different spectral hounsfield unit curve and high-energy virtual monochromatic image characteristics of squamous cell carcinoma compared with nonossified thyroid cartilage.* AJNR Am J Neuroradiol. 2015 Jun;36(6):1194-200 Authors: Forghani R, Levental M, Gupta R, Lam S, Dadfar N, Curtin HD Abstract BACKGROUND AND PURPOSE: The attenuation of normal nonossified thyroid cartilage can be similar to that of head and neck squamous cell carcinoma on CT. We compared dual-energy CT spectral Hounsfield unit attenuation char...περισσότερα »
Package architecture and component design for an implanted neural stimulator with closed loop control.
*Package architecture and component design for an implanted neural stimulator with closed loop control.* Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:7825-7830 Authors: Bjune CK, Marinis TF, Brady JM, Moran J, Wheeler J, Sriram TS, Parks PD, Widge AS, Dougherty DD, Eskandar EN Abstract An implanted neural stimulator with closed loop control requires electrodes for stimulation pulses and recording neuron activity. Our system features arrays of 64 electrodes. Each electrode can be addressed through a cross bar switch, to enable it to be used for stimulation or recording. This el...περισσότερα »
Updates in anterior skull base reconstruction.
*Updates in anterior skull base reconstruction.* Curr Opin Otolaryngol Head Neck Surg. 2016 Feb;24(1):75-82 Authors: Zuniga MG, Turner JH, Chandra RK Abstract PURPOSE OF REVIEW: This article summarizes the indications and surgical techniques for the reconstructions of anterior skull base defects. RECENT FINDINGS: There is increasing popularity of the vascularized pedicled flaps in endoscopic skull base surgery for the successful reconstruction of anterior skull base defects, compared with the use of free-tissue grafts. The location and size of the defect as well as the rate of ce... περισσότερα »
Endoscopic Modified Transseptal Transsphenoidal Approach for Maximal Preservation of Sinonasal Quality of Life and Olfaction.
*Endoscopic Modified Transseptal Transsphenoidal Approach for Maximal Preservation of Sinonasal Quality of Life and Olfaction.* World Neurosurg. 2015 Dec 27; Authors: Hong SD, Nam DH, Kong DS, Kim HY, Chung SK, Dhong HJ Abstract OBJECTIVE: Patients experience significant postoperative sinonasal symptoms for the first few months after endoscopic transnasal transsphenoidal approach (ETN-TSA) surgery. We modified this technique by bypassing the nasal mucosa and approaching through the septum bilaterally. In this study, we analyze whether these technical modifications, which we have ... περισσότερα »
[Epistaxis following skull trauma].
*[Epistaxis following skull trauma].* Ned Tijdschr Geneeskd. 2015;159:A9352 Authors: Nooij RP, van Dijk JM, Groen RJ, Uyttenboogaart M, Eshghi OS, Kosten-Meijer AG Abstract BACKGROUND: Epistaxis is a common problem, which is usually benign in nature. In some cases, however, epistaxis is a symptom of a severe underlying condition. CASE DESCRIPTION: A 20-year-old male was treated conservatively following head injury with craniofacial and base-of-skull fractures. Recurrent episodes of epistaxis occurred some weeks after treatment. Further investigation showed an extradural dissecti... περισσότερα »
Achieving ventricular rate control using metoprolol in beta-blocker naïve patients versus patients on chronic beta-blocker therapy
Publication date: Available online 7 January 2016 *Source:*The American Journal of Emergency Medicine Author(s): Patricia Kuang, Nathan D. Mah, Cassie A. Barton, Andrea J. Miura, Laura R. Tanas, Ran Ran Study ObjectiveTo evaluate the difference in ventricular rate control using an intravenous (IV) metoprolol regimen commonly used in clinical practice in patients receiving chronic beta-blocker therapy compared to patients considered beta-blocker naïve admitted to the emergency department (ED) for atrial fibrillation (AF) with rapid ventricular rate (RVR).MethodsA single-center retros...περισσότερα »
Physical exercise modulates the homeostasis of human regulatory T cells
[image: gr1.sml] A sedentary lifestyle increases the risk for various medical conditions, whereas regular physical activity (PA) has been shown to promote health and reduce the risk of developing chronic disorders such as cardiovascular disease and cancer, which are prevalent in industrialized countries.1 The cellular and molecular mechanisms by which PA mediates its beneficial effects are poorly understood. Because a common etiologic factor for many noncommunicable diseases of affluence is persistent sterile inflammation, PA could exert part of its effects by dampening chronic lo... περισσότερα »
Big atria, little P-waves: unexpected mismatch between chamber volume and electrocardiogram signal in “false” atrial-fibrillation
Publication date: Available online 7 January 2016 *Source:*The American Journal of Emergency Medicine Author(s): Giuseppe Carpagnano, Riccardo Ieva, Michele Correale, Matteo Di Biase, Natale Daniele Brunetti from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mEImBN via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1MVvxIe via IFTTT
Chromosomal microarray provides enhanced targetable gene aberration detection when paired with next generation sequencing panel in profiling lung and colorectal tumors
Publication date: Available online 6 January 2016 *Source:*Cancer Genetics Author(s): S Mukherjee, Z Ma, S Wheeler, M Sathanoori, C Coldren, JL Prescott, N Kozyr, M Bouzyk, M Correll, H Ho, P Chandra, PA Lennon Development of targeted therapies based on specific genomic alterations have altered the treatment and management of lung and colorectal cancers. Chromosomal microarray (CMA) has allowed identification of copy number variations (CNVs) in lung and colorectal cancers in great detail, and Next-Generation Sequencing (NGS) is used extensively to analyze the genome of cancers for m...περισσότερα »
Effects of platelet-rich plasma in association with bone grafts in maxillary sinus augmentation: a systematic review and meta-analysis
This systematic review evaluated the effect on bone formation and implant survival of combining platelet-rich plasma (PRP) with bone grafts in maxillary augmentation. A comprehensive review of articles listed in the PubMed/MEDLINE, Embase, and Cochrane Library databases covering the period January 2000 to January 2015 was performed. The meta-analysis was based on bone formation for which the mean difference (MD, in millimetres) was calculated. Implant survival was assessed as a dichotomous outcome and evaluated using the risk ratio (RR) with 95% confidence interval (CI). from #Γνα...περισσότερα »
Prospective, Randomized, Double Blind Controlled Trial Comparing Vapocoolant Spray versus Placebo Spray in Adults Undergoing Venipuncture
Publication date: Available online 7 January 2016 *Source:*The American Journal of Emergency Medicine Author(s): Sharon E. Mace IntroductionTopical anesthetics are used to decrease procedural pain such as venipuncture. Advantages of vapocoolants include rapid onset, ease of application, low cost, and lack of associated pain of injection and other needle stick-related risks. We hypothesized that the pain of venipuncture would be reduced by at least 1.8 points on a 10-point numerical rating scale after application of a vapocoolant compared with placebo.MethodsWe conducted a prospectiv...περισσότερα »
New drug may overcome treatment resistance in a high-risk children’s cancer
Paediatric oncologists from The Children's Hospital of Philadelphia (CHOP) have reported their latest results in devising new treatments for stubbornly deadly forms of the childhood cancer neuroblastoma. Building on their previous experiences in treating… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RbLIsD via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1S5V0q8 via IFT...περισσότερα »
Study shows statins could be effective against small cell lung cancer
In a recent study, researchers at Cancer Treatment Centers of America (CTCA) at Western Regional Medical Center (Western), in collaboration with international colleagues, found that statins could be an effective therapeutic against metastatic small cell… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RbLIc1 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1S5V0q2 via IFTT... περισσότερα »
Being overweight or obese could cause around 700,000 new UK cancers by 2035 https://t.co/0kSxaBGEYK
Being overweight or obese could cause around 700,000 new UK cancers by 2035 https://t.co/0kSxaBGEYK from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/685058834180796416 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1S5V0qa via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZbMkDb via IFTTT
Physical exercise modulates the homeostasis of human regulatory T cells
[image: gr1.sml] A sedentary lifestyle increases the risk for various medical conditions, whereas regular physical activity (PA) has been shown to promote health and reduce the risk of developing chronic disorders such as cardiovascular disease and cancer, which are prevalent in industrialized countries.1 The cellular and molecular mechanisms by which PA mediates its beneficial effects are poorly understood. Because a common etiologic factor for many noncommunicable diseases of affluence is persistent sterile inflammation, PA could exert part of its effects by dampening chronic lo... περισσότερα »
Effect of intranasal steroids on rhinosinusitis after radiotherapy for nasopharyngeal carcinoma: clinical study
Research Articles S Feng, Y Fan, Z Liang, G Yang, Z Liao, L Guo The Journal of Laryngology Otology, FirstView Article(s), 7 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from ! ORL via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1JwbTHI via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1MVtROO via IFTTT
Tracheal agenesis, a frightening scenario
Rapid Communication H Mohammed, K West, J Bewick, M Wickstead The Journal of Laryngology Otology, FirstView Article(s), 4 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from ! ORL via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PgBSQd via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZbKB0C via IFTTT
ENT and airways in the emergency department: national survey of junior doctors’ knowledge and skills
Research Articles K L Whitcroft, B Moss, A Mcrae The Journal of Laryngology Otology, FirstView Article(s), 7 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from ! ORL via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PgBSQ6 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1MVtQKP via IFTTT
Somatic arousal and sleepiness/fatigue among patients with sleep-disordered breathing
Abstract Objectives In a large clinical sample, we tested the hypothesis that levels of sleepiness and fatigue among upper airway resistance syndrome (UARS) patients are correlated with levels of somatic arousal (SA; reflecting the sympathetic nervous system component of the stress response). We also tested the correlations of post-treatment change in these three parameters, and we extended the investigation to obstructive sleep apnea/hypopnea (OSA/H) patients. Methods From 5 years of patient data, we obtained scores on the body sensation questionnaire (BSQ), measuring the level ... περισσότερα »
Physical exercise modulates the homeostasis of human regulatory T cells
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
A sedentary lifestyle increases the risk for various medical conditions, whereas regular physical activity (PA) has been shown to promote health and reduce the risk of developing chronic disorders such as cardiovascular disease and cancer, which are prevalent in industrialized countries.1 The cellular and molecular mechanisms by which PA mediates its beneficial effects are poorly […]
Clinical diagnostics and therapy monitoring in the congenital disorders of glycosylation
Abstract Abnormal protein glycosylation is observed in many common disorders like cancer, inflammation, Alzheimer's disease and diabetes. However, the actual use of this information in clinical diagnostics is still very limited. Information is usually derived from analysis of total serum N-glycan profiling methods, whereas the current use of glycoprotein biomarkers in the clinical setting is commonly based on protein levels. It can be envisioned that combining protein levels and their glycan isoforms would increase specificity for early diagnosis and therapy monitoring. To establi... περισσότερα »
What results to disclose, when, and who decides? Healthcare professionals’ views on prenatal chromosomal microarray analysis
Abstract Objectives This study explored the views of healthcare-professionals (HCPs) in the UK about what information should be disclosed; when; and whether women/parents should be given a choice as to what they wish to know. Methods Q-methodology was used to assess the views of forty HCPs (genetic healthcare professionals, fetal medicine experts, lab-scientists). Results Most participants agreed that variants of unknown clinical significance should not be disclosed. Participants were divided between those who considered variants of uncertain clinical significance helpful for pa...περισσότερα »
Cleft characteristics and treatment outcomes in hemifacial microsomia compared to non-syndromic cleft lip/palate
The goal of this study was to describe the clinical characteristics and treatment outcomes of patients with hemifacial microsomia (HFM) and cleft lip/palate (CL/P), and to compare them to a historic cohort of patients with non-syndromic CL/P treated at the same centre. A retrospective review of patients with HFM and CL/P was performed; the main outcome measures assessed were cleft type/side, surgical outcome, midfacial retrusion, and speech. Twenty-six patients (13 male, 13 female; mean age 22.7±14.9, range 1–52 years) with cleft lip with/without cleft palate (CL±P) were identifie...περισσότερα »
Treatment of exophthalmos and strabismus surgery in thyroid-associated orbitopathy
Endocrine orbitopathy (EO) can have important consequences, such as exophthalmos and restrictive strabismus. A retrospective study was performed of 35 patients with EO who underwent orbital decompression surgery and restrictive strabismus correction. Two surgical techniques for orbital decompression were analyzed: fat decompression by Olivari technique and three-wall bony expansion with fat decompression. Strabismus surgery was performed using adjustable or non-adjustable sutures under topical anaesthesia. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1TFxhLc v... περισσότερα »
Prehospital Indicators for Disaster Preparedness and Response: New York City Emergency Medical Services in Hurricane Sandy
Research Articles Silas W. Smith, James Braun, Ian Portelli, Sidrah Malik, Glenn Asaeda, Elizabeth Lancet, Binhuan Wang, Ming Hu, David C. Lee, David J. Prezant, Lewis R. Goldfrank Disaster Medicine and Public Health Preparedness, FirstView Article(s), 11 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RbLJfY via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs b... περισσότερα »
Issue Information
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1TGXNno via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1VM1Z6w via IFTTT
Effects of platelet-rich plasma in association with bone grafts in maxillary sinus augmentation: a systematic review and meta-analysis
This systematic review evaluated the effect on bone formation and implant survival of combining platelet-rich plasma (PRP) with bone grafts in maxillary augmentation. A comprehensive review of articles listed in the PubMed/MEDLINE, Embase, and Cochrane Library databases covering the period January 2000 to January 2015 was performed. The meta-analysis was based on bone formation for which the mean difference (MD, in millimetres) was calculated. Implant survival was assessed as a dichotomous outcome and evaluated using the risk ratio (RR) with 95% confidence interval (CI). from #Γνα...περισσότερα »
Physical exercise modulates the homeostasis of human regulatory T cells
[image: gr1.sml] A sedentary lifestyle increases the risk for various medical conditions, whereas regular physical activity (PA) has been shown to promote health and reduce the risk of developing chronic disorders such as cardiovascular disease and cancer, which are prevalent in industrialized countries.1 The cellular and molecular mechanisms by which PA mediates its beneficial effects are poorly understood. Because a common etiologic factor for many noncommunicable diseases of affluence is persistent sterile inflammation, PA could exert part of its effects by dampening chronic lo... περισσότερα »
Sources of injustice among individuals with persistent pain following musculoskeletal injury
Abstract Evidence supports the negative impact of perceived injustice on recovery following injury. However, little is known about sources that contribute to injustice perceptions in this context. Therefore, this study systematically investigated sources of injustice following painful musculoskeletal injury. Following completion of the Injustice Experiences Questionnaire (IEQ) and measures of pain, depression, and disability, participants completed a semi-structured interview to discuss reasons underlying their IEQ responses. On average, the sample was experiencing moderate levels ... περισσότερα »
Psychometric Properties of a Brief Instrument to Assess Perceptions of Injustice Associated with Debilitating Health and Mental Health Conditions
Abstract The present study examined the psychometric properties of a shortened and simplified version of the Injustice Experience Questionnaire (IEQ). The instructional set of the original IEQ was modified to make it better suited to the context of debilitating health and mental health conditions that do not necessarily arise as a result of injury. The number of items was reduced from 12 to 5, and the response scale was simplified. The Injustice Experiences Questionnaire – Short Form (IEQ-SF) was administered to individuals diagnosed with a chronic musculoskeletal (MSK) condition (... περισσότερα »
Being overweight or obese could cause around 700,000 new UK cancers by 2035 https://t.co/0kSxaBGEYK
Being overweight or obese could cause around 700,000 new UK cancers by 2035 https://t.co/0kSxaBGEYK from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/685058834180796416 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1S5V0qa via IFTTT
Perceived Injustice Predicts Intention to Litigate: Findings from a Spinal Cord Injury Sample
Abstract The current study examined the association between perceived injustice (assessed by the Injustice Experiences Questionnaire) and intent to litigate in a sample of individuals who had recently suffered a spinal cord injury and were currently on an inpatient rehabilitation unit. Higher perception of injustice was associated with reported interest in litigation. In logistic regression analyses, perceived injustice uniquely differentiated between individuals who foresaw involvement in litigation versus those who did not, with the blame/unfairness factor of the Injustice Exper... περισσότερα »
New drug may overcome treatment resistance in a high-risk children’s cancer
Paediatric oncologists from The Children's Hospital of Philadelphia (CHOP) have reported their latest results in devising new treatments for stubbornly deadly forms of the childhood cancer neuroblastoma. Building on their previous experiences in treating… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RbLIsD via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1S5V0q8 via IFTTT
Lung cancer clinical trial finds lung function without additional imaging
A newly NIH funded clinical trial (NCT02528942) by University of Colorado Cancer Center investigators and collaborators at Beaumont Health in Michigan and the University of Texas Medical Branch is evaluating a new method for pinpointing and sparing… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1O6FoPn via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1VM1Wb5 via IFTTT
Study shows statins could be effective against small cell lung cancer
In a recent study, researchers at Cancer Treatment Centers of America (CTCA) at Western Regional Medical Center (Western), in collaboration with international colleagues, found that statins could be an effective therapeutic against metastatic small cell… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RbLIc1 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1S5V0q2 via IFTTT
Sugar tax and screening: listen to the evidence
"Sugar, rum, and tobacco are commodities which are nowhere necessaries of life, which are become objects of almost universal consumption, and which are therefore extremely proper subjects of… [image: recent?d=yIl2AUoC8zA] [image: recent?d=dnMXMwOfBR0] [image: recent?i=oVuAPq7Ta9Q:Q0_neeaJxjw:V_sGLiP] [image: recent?d=qj6IDK7rITs] [image: recent?i=oVuAPq7Ta9Q:Q0_neeaJxjw:gIN9vFw] [image: recent?d=l6gmwiTKsz0] [image: recent?d=7Q72WNTAKBA] [image: recent?i=oVuAPq7Ta9Q:Q0_neeaJxjw:F7zBnMy] [image: recent?i=oVuAPq7Ta9Q:Q0_neeaJxjw:-BTjWOF] [image: 1O6FmqG] from #ORL-AlexandrosSfakiana... περισσότερα »
Package architecture and component design for an implanted neural stimulator with closed loop control.
*Package architecture and component design for an implanted neural stimulator with closed loop control.* Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:7825-7830 Authors: Bjune CK, Marinis TF, Brady JM, Moran J, Wheeler J, Sriram TS, Parks PD, Widge AS, Dougherty DD, Eskandar EN Abstract An implanted neural stimulator with closed loop control requires electrodes for stimulation pulses and recording neuron activity. Our system features arrays of 64 electrodes. Each electrode can be addressed through a cross bar switch, to enable it to be used for stimulation or recording. This el...περισσότερα »
Updates in anterior skull base reconstruction.
*Updates in anterior skull base reconstruction.* Curr Opin Otolaryngol Head Neck Surg. 2016 Feb;24(1):75-82 Authors: Zuniga MG, Turner JH, Chandra RK Abstract PURPOSE OF REVIEW: This article summarizes the indications and surgical techniques for the reconstructions of anterior skull base defects. RECENT FINDINGS: There is increasing popularity of the vascularized pedicled flaps in endoscopic skull base surgery for the successful reconstruction of anterior skull base defects, compared with the use of free-tissue grafts. The location and size of the defect as well as the rate of ce... περισσότερα »
Endoscopic Modified Transseptal Transsphenoidal Approach for Maximal Preservation of Sinonasal Quality of Life and Olfaction.
*Endoscopic Modified Transseptal Transsphenoidal Approach for Maximal Preservation of Sinonasal Quality of Life and Olfaction.* World Neurosurg. 2015 Dec 27; Authors: Hong SD, Nam DH, Kong DS, Kim HY, Chung SK, Dhong HJ Abstract OBJECTIVE: Patients experience significant postoperative sinonasal symptoms for the first few months after endoscopic transnasal transsphenoidal approach (ETN-TSA) surgery. We modified this technique by bypassing the nasal mucosa and approaching through the septum bilaterally. In this study, we analyze whether these technical modifications, which we have ... περισσότερα »
[Epistaxis following skull trauma].
*[Epistaxis following skull trauma].* Ned Tijdschr Geneeskd. 2015;159:A9352 Authors: Nooij RP, van Dijk JM, Groen RJ, Uyttenboogaart M, Eshghi OS, Kosten-Meijer AG Abstract BACKGROUND: Epistaxis is a common problem, which is usually benign in nature. In some cases, however, epistaxis is a symptom of a severe underlying condition. CASE DESCRIPTION: A 20-year-old male was treated conservatively following head injury with craniofacial and base-of-skull fractures. Recurrent episodes of epistaxis occurred some weeks after treatment. Further investigation showed an extradural dissecti... περισσότερα »
A brain-lesion pattern based algorithm for the diagnosis of posttraumatic olfactory loss.
*A brain-lesion pattern based algorithm for the diagnosis of posttraumatic olfactory loss.* Rhinology. 2015 Dec 1;53(4):365-370 Authors: Lő Tsch J, Reither N, Bogdanov V, Hähner A, Ultsch A, Hill K, Hummel T Abstract BACKGROUND: Brain areas processing olfactory information exhibit functionally relevant morphological dynamics. This suggests the exploitation of anatomical information in the diagnosis of an olfactory dysfunction. Following previous identifications of olfactory eloquent areas such as the olfactory bulbs and tracts, we focused at a brain-morphology based algorithm f... περισσότερα »
Follow-up of Thalidomide treatment in patients with Hereditary Haemorrhagic Telangiectasia.
*Follow-up of Thalidomide treatment in patients with Hereditary Haemorrhagic Telangiectasia.* Rhinology. 2015 Dec 1;53(4):340-344 Authors: Hosman A, Westermann CJ, Snijder R, Disch F, Mummery CL, Mager JJ Abstract BACKGROUND: Patients with a hereditary vascular disorder called Rendu-Osler-Weber syndrome (Hereditary Haemorrhagic Telangiectasia, HHT) haemorrhage easily due to weak-walled vessels. Haemorrhage in lungs or brain can be fatal but patients suffer most from chronic and prolonged nosebleeds (epistaxis), the frequency and intensity of which increases with age. Several yea... περισσότερα »
A time-frequency respiration tracking system using non-contact bed sensors with harmonic artifact rejection.
*A time-frequency respiration tracking system using non-contact bed sensors with harmonic artifact rejection.* Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:8111-8114 Authors: Beattie ZT, Jacobs PG, Riley TC, Hagen CC Abstract Sleep apnea is a breathing disorder that affects many individuals and has been associated with serious health conditions such as cardiovascular disease. Clinical diagnosis of sleep apnea requires that a patient spend the night in a sleep clinic while being wired up to numerous obtrusive sensors. We are developing a system that utilizes respiration rate and... περισσότερα »
Horner syndrome in glandular fever: a case report.
*Horner syndrome in glandular fever: a case report.* J Laryngol Otol. 2016 Jan 6;:1-3 Authors: West EV, Sheerin F, Bates JE Abstract OBJECTIVE: This study aimed to present and discuss the case of a patient with known glandular fever who presented with Horner syndrome. CASE REPORT: A 35-year-old patient with known glandular fever developed acute unilateral Horner syndrome, a previously undescribed complication of this common illness. Magnetic resonance imaging and magnetic resonance angiography showed that enlarged intra-carotid sheath lymphoid tissue was likely to be the underlyi...περισσότερα »
Endoscopic dacryocystorhinostomy with and without silicone intubation: 4 years retrospective study.
*Endoscopic dacryocystorhinostomy with and without silicone intubation: 4 years retrospective study.* Eur Arch Otorhinolaryngol. 2016 Jan 5; Authors: Longari F, Dehgani Mobaraki P, Ricci AL, Lapenna R, Cagini C, Ricci G Abstract The objective of this study is to assess different outcomes between endoscopic dacryocystorhinostomy (En-DCR) with and without silicone intubation. We retrospectively analyzed 84 patients (89 procedures), suffering from chronic epiphora for primary acquired nasolacrimal duct obstruction, treated with En-DCR and divided into two groups depending on silic...περισσότερα »
Early enteral nutrition versus late enteral nutrition for burns patients: A systematic review and meta-analysis
Burns from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1mHZ8PX via IFTTT
Patient education and follow-up as an intervention for hypertensive patients discharged from an emergency department: a randomized control trial study protocol
BMC Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Jw9hd7 via IFTTT
Needle decompression of tension pneumothorax: Population-based epidemiologic approach to adequate needle length in healthy volunteers in Northeast Germany
The Journal of Trauma and Acute Care Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1mHZ6aG via IFTTT
Use of oritavancin in acute bacterial skin and skin structure infections patients receiving intravenous antibiotics: A US hospital budget impact analysis
Clinical Drug Investigation from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Jw9fBU via IFTTT
Clinical outcome of interprosthetic femoral fractures treated with polyaxial locking plates
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Beneficial effects of omega-3 supplement to the enteral feeding in children with mild to moderate sepsis
Journal of Intensive Care Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Jw9gWw via IFTTT
Coronary sinus flow is reduced and recovered with time in viral myocarditis mimicking acute coronary syndrome: a transthoracic doppler echocardiographic study
Journal of Ultrasound in Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1mHZ5DU via IFTTT
Efficacy of nasal cannula oxygen as a preoxygenation adjunct in emergency airway management
Annals of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Jw9f51 via IFTTT
Geographic scope and accessibility of a centralized, electronic consult program for patients with recent fracture
Rural and Remote Health from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1mHZ5DG via IFTTT
Myocardial injury through serum troponin I and echocardiography in anaphylaxis: Takotsubo cardiomyopathy and the kounis hypersensitivity-associated acute coronary syndrome
The American Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Jw9f4P via IFTTT
Follow-up of glycemic control and cardiovascular outcomes in type 2 diabetes
Journal of Vascular Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1mHZ2YD via IFTTT
The impact of clinical decision rules on computed tomography use and yield for pulmonary embolism: a systematic review and meta-analysis
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Antibiotic consumption to detect epidemics of Pseudomonas aeruginosa in a burn centre: A paradigm shift in the epidemiological surveillance of Pseudomonas aeruginosa nosocomial infections
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STONE PLUS: Evaluation of Emergency Department Patients With Suspected Renal Colic, Using a Clinical Prediction Tool Combined With Point-of-Care Limited Ultrasonography
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Bone mineral density aspects in the femoral neck of hip fracture patients
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Conservative management of severe caustic injuries during acute phase leads to superior long-term nutritional and quality of life (QoL) outcome
Langenbeck's Archives of Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Jw9cWT via IFTTT
The relationship between burnout, PTSD symptoms and injuries in firefighters
Occupational Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Jw9e0L via IFTTT
Predictive role of high sensitivity troponin T within four hours from presentation of acute coronary syndrome in elderly patients
BMC Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1mHZ56R via IFTTT
The impact of elective colon resection on rates of emergency surgery for diverticulitis
Annals of Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Jw9cpL via IFTTT
Operative vs nonoperative management of pediatric blunt pancreatic trauma: evaluation of the national trauma data bank
Journal of the American College of Surgeons from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1VLNMXr via IFTTT
Issue Information
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1TGXNno via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Prehospital Indicators for Disaster Preparedness and Response: New York City Emergency Medical Services in Hurricane Sandy
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Research Articles Silas W. Smith, James Braun, Ian Portelli, Sidrah Malik, Glenn Asaeda, Elizabeth Lancet, Binhuan Wang, Ming Hu, David C. Lee, David J. Prezant, Lewis R. Goldfrank Disaster Medicine and Public Health Preparedness, FirstView Article(s), 11 pages Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RbLJfY via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete […]
Physical exercise modulates the homeostasis of human regulatory T cells
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
A sedentary lifestyle increases the risk for various medical conditions, whereas regular physical activity (PA) has been shown to promote health and reduce the risk of developing chronic disorders such as cardiovascular disease and cancer, which are prevalent in industrialized countries.1 The cellular and molecular mechanisms by which PA mediates its beneficial effects are poorly […]
Sources of injustice among individuals with persistent pain following musculoskeletal injury
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Evidence supports the negative impact of perceived injustice on recovery following injury. However, little is known about sources that contribute to injustice perceptions in this context. Therefore, this study systematically investigated sources of injustice following painful musculoskeletal injury. Following completion of the Injustice Experiences Questionnaire (IEQ) and measures of pain, depression, and disability, participants […]
Psychometric Properties of a Brief Instrument to Assess Perceptions of Injustice Associated with Debilitating Health and Mental Health Conditions
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract The present study examined the psychometric properties of a shortened and simplified version of the Injustice Experience Questionnaire (IEQ). The instructional set of the original IEQ was modified to make it better suited to the context of debilitating health and mental health conditions that do not necessarily arise as a result of injury. The […]
Perceived Injustice Predicts Intention to Litigate: Findings from a Spinal Cord Injury Sample
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract The current study examined the association between perceived injustice (assessed by the Injustice Experiences Questionnaire) and intent to litigate in a sample of individuals who had recently suffered a spinal cord injury and were currently on an inpatient rehabilitation unit. Higher perception of injustice was associated with reported interest in litigation. In logistic regression […]
Being overweight or obese could cause around 700,000 new UK cancers by 2035 https://t.co/0kSxaBGEYK
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Being overweight or obese could cause around 700,000 new UK cancers by 2035 https://t.co/0kSxaBGEYK from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/685058834180796416 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
New drug may overcome treatment resistance in a high-risk children’s cancer
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Paediatric oncologists from The Children’s Hospital of Philadelphia (CHOP) have reported their latest results in devising new treatments for stubbornly deadly forms of the childhood cancer neuroblastoma. Building on their previous experiences in treating… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RbLIsD via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Lung cancer clinical trial finds lung function without additional imaging
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
A newly NIH funded clinical trial (NCT02528942) by University of Colorado Cancer Center investigators and collaborators at Beaumont Health in Michigan and the University of Texas Medical Branch is evaluating a new method for pinpointing and sparing… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1O6FoPn via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 […]
Study shows statins could be effective against small cell lung cancer
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
In a recent study, researchers at Cancer Treatment Centers of America (CTCA) at Western Regional Medical Center (Western), in collaboration with international colleagues, found that statins could be an effective therapeutic against metastatic small cell… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RbLIc1 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Cleft characteristics and treatment outcomes in hemifacial microsomia compared to non-syndromic cleft lip/palate
The goal of this study was to describe the clinical characteristics and treatment outcomes of patients with hemifacial microsomia (HFM) and cleft lip/palate (CL/P), and to compare them to a historic cohort of patients with non-syndromic CL/P treated at the same centre. A retrospective review of patients with HFM and CL/P was performed; the main outcome measures assessed were cleft type/side, surgical outcome, midfacial retrusion, and speech. Twenty-six patients (13 male, 13 female; mean age 22.7±14.9, range 1–52 years) with cleft lip with/without cleft palate (CL±P) were identifie...περισσότερα »
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