Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τρίτη 16 Φεβρουαρίου 2016

OtoRhinoLaryngology & Medicine,New Articles,February 16th,2016,a


Hidradenocarcinoma presenting as soft tissue mass: Case report with cytomorphologic description, histologic correlation, and differential diagnosis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
*Hidradenocarcinoma presenting as soft tissue mass: Case report with cytomorphologic description, histologic correlation, and differential diagnosis.* Diagn Cytopathol. 2016 Feb 15; Authors: Jinnah AH, Emory CL, Mai NH, Bergman S, Salih ZT Abstract Hidradenocarcinoma (HAC) is a rare adenexal tumor with a propensity for the head and neck region and extremities. We report a case of hidradenocarcinnoma in a 56-year-old woman with a mass on her right palm sampled by fine-needle aspiration and later confirmed on histological examination. Fine-needle aspiration cytology revealed a dual...περισσότερα »

Gamma Heavy Chain Disease with T-cell Large Granular Lymphocytic Leukemia: A Case Report and Review of the Literature.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
*Gamma Heavy Chain Disease with T-cell Large Granular Lymphocytic Leukemia: A Case Report and Review of the Literature.* Intern Med. 2016;55(4):399-403 Authors: Iijima M, Sekiguchi N, Nagata A, Wagatsuma M, Midorikawa K, Kurimoto M, Noto S, Yamada K, Takezako N Abstract Gamma heavy chain disease (gHCD) is a rare lymphoproliferative disorder characterized by the production of a truncated immunoglobulin heavy chain. Although some cases of gHCD are concurrent with other lymphoid neoplasms, few have been reported. We herein present the case of a 73-year-old woman with gHCD and T-cell... περισσότερα »

Intussusception as clinical presentation of primary non-Hodgkin lymphoma of the colon in a HIV-patient.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
*Intussusception as clinical presentation of primary non-Hodgkin lymphoma of the colon in a HIV-patient.* Rev Esp Enferm Dig. 2016 Feb 15;108 Authors: Corti M, Boschi A, Del Portillo Á, Méndez N, Campitelli A, Narbaitz M Abstract Intestinal intussusception rarely occurs in the adult population and accounts only for 1% to 5% of all the causes of intestinal obstruction. This complication is more frequent in the small bowel and can be due to different aetiologies, including inflammatory, infectious or neoplastic diseases. Malignancies account for 50% to 60% of all cases of colon in...περισσότερα »

Cytology of low-grade cribriform cystadenocarcinoma in salivary glands: Cytological and immunohistochemical distinctions from other salivary gland neoplasms.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
*Cytology of low-grade cribriform cystadenocarcinoma in salivary glands: Cytological and immunohistochemical distinctions from other salivary gland neoplasms.* Diagn Cytopathol. 2016 Mar;44(3):241-5 Authors: Ohta Y, Hirota Y, Kohno Y, Kishimoto K, Norose T, Ohike N, Takimoto M, Shiokawa A, Ota H Abstract Low-grade cribriform cystadenocarcinoma of the parotid gland is rare malignancy that is classified as a variant of cystadenocarcinoma. In routine cytologic slides from fine-needle aspiration of a parotid gland, we found several pseudopapillary clusters comprising mucus-producing ... περισσότερα »

Merkel cell carcinoma of the head and neck: poorer prognosis than non-head and neck sites.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
*Merkel cell carcinoma of the head and neck: poorer prognosis than non-head and neck sites.* J Laryngol Otol. 2016 Feb 15;:1-5 Authors: Morand GB, Madana J, Da Silva SD, Hier MP, Mlynarek AM, Black MJ Abstract BACKGROUND: Merkel cell carcinoma is a rare, aggressive neurocutaneous malignancy. This study investigated whether patients with Merkel cell carcinoma in the head and neck had poorer outcomes than patients with Merkel cell carcinoma located elsewhere. METHODS: A retrospective study was performed of patients with Merkel cell carcinoma treated at the Jewish General Hospital in... περισσότερα »

A case of hairy cell leukemia variant.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
Related Articles *A case of hairy cell leukemia variant.* Rom J Morphol Embryol. 2015;56(2):553-6 Authors: Găman AM, Dobrea CM, Găman MA Abstract Hairy cell leukemia variant (HCLv) is a rare B-cell chronic lymphoproliferative disorder with features of the classic HCL but presenting some particularities, a poor response to conventional therapy of classic HCL and a more aggressive course of disease with shorter survival than classic HCL. We present a case of a 52-year-old man hospitalized in July 2012 in the Clinic of Hematology of Craiova, Romania, having splenomegaly, leukocytos... περισσότερα »

Arteriovenous synovial hemangioma of the popliteal fossa diagnosed in an adolescent with history of unilateral congenital clubfoot: case report and a single-institution retrospective review.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
Related Articles *Arteriovenous synovial hemangioma of the popliteal fossa diagnosed in an adolescent with history of unilateral congenital clubfoot: case report and a single-institution retrospective review.* Rom J Morphol Embryol. 2015;56(2):549-52 Authors: Derzsi Z, Gurzu S, Jung I, László I, Golea M, Nagy Ö, Pop TS Abstract Synovial hemangioma (SH) is a very rare soft tissue tumor; in our department, SH represented 0.07% from all soft tissue tumors (one case from 1311 soft tissue tumors), and 0.78% from all excised hemangiomas (one case from 128 hemangiomas) diagnosed over a ...περισσότερα »

Incidental finding of a sclerosing hemangioma in a Caucasian woman.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
Related Articles *Incidental finding of a sclerosing hemangioma in a Caucasian woman.* Rom J Morphol Embryol. 2015;56(2):545-8 Authors: Danciu M, Lunguleac T, Grigorescu C Abstract Sclerosing hemangioma of the lung is a rare and mostly benign lung tumor, which affects especially Asian middle-age women (median age of 48 years). We report the case of a 27-year-old woman in which, a premarital routine chest X-ray investigation revealed a 2 cm well-defined opaque nodule in the lower left pulmonary lobe, confirmed by CT scan. Microscopically, the surgically enucleoresected nodule was ...περισσότερα »

Papillary thyroid carcinoma with anaplastic dedifferentiation in the lymph node metastasis - a rare form of presentation even for a tall cell variant.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
Related Articles *Papillary thyroid carcinoma with anaplastic dedifferentiation in the lymph node metastasis - a rare form of presentation even for a tall cell variant.* Rom J Morphol Embryol. 2015;56(2):527-31 Authors: Barbu CG, Florin A, Neamţu MC, Avramescu ET, Terzea D, Miron A, Dănciulescu Miulescu R, Poiană C, Fica S Abstract Papillary thyroid carcinoma (PTC) is well known as a differentiated thyroid carcinoma with an established treatment protocol and high survival rates. Nevertheless, its tall cell variant (TCV) is more frequent diagnosed with larger tumor size, advanced ... περισσότερα »

Sellar Chondroma with Endocrine Dysfunction that Resolved after Surgery: Case Report.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
[image: http:--linkout.jstage.jst.go.jp-logo.gif] Related Articles *Sellar Chondroma with Endocrine Dysfunction that Resolved after Surgery: Case Report.* J Nippon Med Sch. 2015;82(3):146-50 Authors: Hattori Y, Tahara S, Nakakuki T, Takei M, Ishii Y, Teramoto A, Morita A Abstract Chondromas originating from the sella turcica are rare, and the most common initial symptoms are headache and visual disturbance. We describe a case of sellar chondroma with endocrine impairment as an initial manifestation that completely resolved after surgery. A 40-year-old Japanese woman with amenorr... περισσότερα »

Placental mesenchymal dysplasia associated with spontaneous ovarian hyperstimulation syndrome.

Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Placental mesenchymal dysplasia associated with spontaneous ovarian hyperstimulation syndrome.* BMJ Case Rep. 2015;2015 Authors: Davoudian P Abstract Placental mesenchymal dysplasia (PMD) is a rare disorder of unknown aetiology characterised by placentomegaly, serpiginous surface blood vessels and large cystic villi. Although a mimic of molar pregnancies and other entities, it can be distinguished from them by its association with intrauterine growth restriction or death of a relatively normal fetus and its char...περισσότερα »

Proteomics in Toxicology – added value or waste of energies?

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 2 δευτερόλεπτα
Publication date: Available online 15 February 2016 *Source:*Journal of Proteomics Author(s): T. Serchi, A.C. Gutleb, I. Miller from BioChemistry via xlomafota13 on Inoreader http://ift.tt/20B97Ud via IFTTT

Assessment of neuroactive steroids in cerebrospinal fluid comparing acute relapse and stable disease in relapsing-remitting multiple sclerosis

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 2 δευτερόλεπτα
Publication date: Available online 15 February 2016 *Source:*The Journal of Steroid Biochemistry and Molecular Biology Author(s): N.S. Orefice, A. Carotenuto, G. Mangone, B. Bues, R. Rehm, I. Cerillo, F. Saccà, A. Calignano, G. Orefice Previous studies have reported an involvement of neuroactive steroids as neuroprotective and anti-inflammatory agents in neurological disorders such as multiple sclerosis (MS); an analysis of their profile during a specific clinical phase of MS is largely unknown. The pregnenolone (PREG), dehydroepiandrosterone (DHEA), and allopregnanolone (ALLO) profi...περισσότερα »

Apparent mineralocorticoid excess and the long term treatment of genetic hypertension

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 2 δευτερόλεπτα
Publication date: Available online 15 February 2016 *Source:*The Journal of Steroid Biochemistry and Molecular Biology Author(s): Maryam Razzaghy-Azar, Mabel Yau, Ahmed Khattab, Maria I. New Apparent Mineralocorticoid Excess (AME) is a genetic disorder causing severe hypertension, hypokalemia, and hyporeninemic hypoaldosteronism owing to deficient 11 beta-hydroxysteroid dehydrogenase type-2 (11βHSD2) enzyme activity. The 11βHSD2 enzyme confers mineralocorticoid receptor specificity for aldosterone by converting cortisol to its inactive metabolite, cortisone and inactivating the the c...περισσότερα »

Outcomes of chronic frontal sinusitis treated with ethmoidectomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Outcomes of chronic frontal sinusitis treated with ethmoidectomy: a prospective study: Background In medically refractory chronic frontal sinusitis, ethmoidectomy without instrumentation of the frontal ostium may resolve frontal disease. Our aim was to determine the efficacy of ethmoidectomy alone for the treatment of chronic frontal sinusitis. Methods Adults with chronic rhinosinusitis prospectively enrolled in a multicenter study who demonstrated frontal sinusitis on computed tomography were divided into 2 groups: (1) endoscopic sinus surgery (ESS) incorporating ethmoidectomy, bu...περισσότερα »

Caroverine (Spasmium, Spadon, Tinnex) is a drug used as a spasmolytic and otoneuroprotective (inner ear protective)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Ομάδα ATC: A03AX Άλλα φάρμακα για λειτουργικές διαταραχές του εντέρουΤίτλοι κωδικού ΓλώσσαΤίτλος *EL* *Ελληνικά* *Άλλα φάρμακα για λειτουργικές διαταραχές του εντέρου* *EN* *Αγγλικά* *Other drugs for functional bowel disorders*Κατάταξη ομάδας ΕπίπεδοΚωδικόςΤίτλος * 0* *A* *Πεπτική οδός και μεταβολισμός* * 1* *A03* *Φάρμακα για λειτουργικές γαστρεντερικές διαταραχές* * 2* *A03A* *Φάρμακα για λειτουργικές διαταραχές του εντέρου* * 3* *A03AX* *Άλλα φάρμακα για λειτουργικές διαταραχές του εντέρου*Περιεχόμενα ομάδας ΚωδικόςΤίτλος * A03AX01* *Fenpiprane* * A03AX02* *Diisopromine* * A03AX03* *Ch... περισσότερα »

Parent perspectives and reasons for lower urgency paediatric presentations to emergency departments

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Emergency Medicine Australasia from Emergency Medicine via ola Kala on Inoreader http://ift.tt/216aLzg via IFTTT

Reducing a shoulder dislocation without sweating. The Davos technique and its results. evaluation of a nontraumatic, safe, and simple technique for reducing anterior shoulder dislocations

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SuBy6S via IFTTT

Disaster-related injury management: high prevalence of wound infection after Super Typhoon Haiyan

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Disaster Medicine and Public Health Preparedness from Emergency Medicine via ola Kala on Inoreader http://ift.tt/216aLiQ via IFTTT

A randomized controlled trial of the effectiveness of traditional and mobile public health communications with health care providers

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Disaster Medicine and Public Health Preparedness from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SuBwvR via IFTTT

Civil-military engagement: an empirical account of humanitarian perceptions of civil-military coordination during the response to Typhoon Haiyan

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Disaster Medicine and Public Health Preparedness from Emergency Medicine via ola Kala on Inoreader http://ift.tt/216aL2t via IFTTT

Outcomes of Patients With Premature Discontinuation of the 21-h Intravenous N-Acetylcysteine Protocol After Acute Acetaminophen Overdose

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SuBxjn via IFTTT

Therapeutic and recreational methadone cardiotoxicity

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Journal of Forensic and Legal Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/216aNr4 via IFTTT

Clinical response, outbreak investigation, and epidemiology of the fungal meningitis epidemic in the United States: systematic review

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Disaster Medicine and Public Health Preparedness from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SuBvrR via IFTTT

Increased asymmetric dimethylarginine levels in severe transient tachypnea of the newborn

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Journal of Perinatology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/216aNr0 via IFTTT

A comparison of self-reported seat belt usage among the Appalachian and Non-Appalachian United States

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Annals of Epidemiology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SuBvbb via IFTTT

Coping behavior and risk of post-traumatic stress disorder among federal disaster responders

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Disaster Medicine and Public Health Preparedness from Emergency Medicine via ola Kala on Inoreader http://ift.tt/216aL2h via IFTTT

Use of endotracheal tubes with subglottic secretion drainage reduces ventilator-associated pneumonia in trauma patients

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
The Journal of Trauma and Acute Care Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SuBuEb via IFTTT

Low serum vitamin D levels are associated with shorter survival after first-line azacitidine treatment in patients with myelodysplastic syndrome and secondary oligoblastic acute myeloid leukemia

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Clinical Nutrition from Emergency Medicine via ola Kala on Inoreader http://ift.tt/216aNax via IFTTT

Comparison of two successive earthquake awareness campaigns in Israel: improved methodology or a cumulative effect?

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Disaster Medicine and Public Health Preparedness from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SuBt3c via IFTTT

Metabolic crisis occurs with seizures and periodic discharges after brain trauma

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Annals of Neurology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/216aNal via IFTTT

Are we ready for mass fatality incidents? preparedness of the US mass fatality infrastructure

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Disaster Medicine and Public Health Preparedness from Emergency Medicine via ola Kala on Inoreader http://ift.tt/216aKLX via IFTTT

Perceptual detection of subtle dysphonic traits in individuals with cervical spinal cord injury using an audience response systems approach

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Journal of Voice from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SuBsMC via IFTTT

Road safety environment around urban schools of Dharwad, India: a cross-sectional study

AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 4 δευτερόλεπτα
2016-02-16T04-01-37Z *Source:* International Journal of Community Medicine and Public Health Chidendra M. Shettar, Pushpa S. Patil. Background: India accounts to 10% of global road deaths. In 2013 around 1,40,000 people were killed and 5,00,000 were severely injured or disabled. Road traffic injuries (RTIs) are a major health problem among young people. Children are vulnerable road users and safety issues near school zones are the major cause of concern. Improper road safety measures can seriously affect the safeness and security of school children. In this context the study was con...περισσότερα »

Diode endovascular laser treatment in venous malformations of the upper aerodigestive tract

Publication date: Available online 15 February 2016 Source:Journal of Cranio-Maxillofacial Surgery Author(s): François Simon, Nicolas Le Clerc, Didier Salvan, Elisabeth Sauvaget, Benoît Faucon, Michel Borsik, Philippe Herman, Annouk Bisdorff PurposeVenous malformations of the upper aerodigestive tract can cause pain, dysphagia, obstructive sleep apnea, and rarely bleeding. We studied 980-nm diode endovenous laser therapy.Material and MethodsThis […]

Shiitake mushroom dermatitis

A man presented with a sudden onset, non-pruritic, flagellate, non-blanching truncal rash two days after eating shiitake mushrooms. Dermatographism (physical urticaria with exaggerated wealing when… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1okmig3 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OdShni via IFTTT

Transient neonatal zinc deficiency

A 4 month old, preterm, exclusively breastfed baby presented with a two month history of erythematous, crusted plaques on her face (A) and anogenital region, irritability, and diarrhoea. Skin swabs… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1SuS5Ys via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OdSg2I via IFTTT

Crescentic flap for the reconstruction of the nose after skin cancer resection

Publication date: Available online 16 February 2016 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Federica Arginelli, Attilio Carlo Salgarelli, Barbara Ferrari, Amanda Losi, Pierantonio Bellini, Cristina Magnoni PurposeNon-melanoma skin cancers are the most frequent skin tumours; in 25.5% of cases, they are reported to affect the nasal area. For an excellent surgical outcome, first of all the […]

Abdominal discomfort with an alarming scan

A 74 year old woman presented after two weeks of rigors and abdominal discomfort. She had raised inflammatory markers and cholestatic liver function tests. After unhelpful ultrasound and magnetic… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1SuRsOB via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1QiIdkr via IFTTT

A Study to Compare the Efficacy and Safety of Obinutuzumab + Venetoclax versus Obinutuzumab + Chlorambucil in Patients With Chronic Lymphocytic Leukemia (CLL14)

Oncol Res Treat 2016;39:69-71 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1LrmjnR via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OdSg2G via IFTTT

Lateral Tarsotomy: A Practical Alternative to Lateral Canthotomy to Increase Orbital Access

Publication date: Available online 16 February 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Hany A. Emam, Mark R. Stevens, Peter E. Larsen, Courtney A. Jatana ObjectiveTransconjunctival approach to the lower 1/3 of the orbit is commonly used to avoid transcutaneous incisions when surgical access is needed. A lateral canthotomy is used […]

Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?

Abstract Background A porcine model of haematogenous Staphylococcus aureus sepsis has previously been established in our research group. In these studies, pigs developed severe sepsis including liver dysfunction during a 48 h study period. As pigs were awake during the study, animal welfare was challenged by the severity of induced disease, which in some cases […]

The effects of surgical expansion of the maxillary arch and its consequences for the incisor axis

Publication date: Available online 16 February 2016 Source:Journal of Cranio-Maxillofacial Surgery Author(s): A. Moralis, K. Zitzmann, M. Gosau, D. Schlegel PurposeReduced transverse maxillary dental arch width may be treated either by surgically supported rapid maxillary expansion (SRME) with conservative orthodontic appliances or by means of Le Fort I osteotomy (LFIO). Both are means of transverse […]

A review of trabecular bone functional adaptation: what have we learned from trabecular analyses in extant hominoids and what can we apply to fossils?

Abstract Many of the unresolved debates in palaeoanthropology regarding evolution of particular locomotor or manipulative behaviours are founded in differing opinions about the functional significance of the preserved external fossil morphology. However, the plasticity of internal bone morphology, and particularly trabecular bone, allowing it to respond to mechanical loading during life means that it can […]

Double seal technique to obliterate the eustachian tube orifice: a novel method for the treatment of recalcitrant cerebrospinal fluid leak.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Double seal technique to obliterate the eustachian tube orifice: a novel method for the treatment of recalcitrant cerebrospinal fluid leak.* J Laryngol Otol. 2016 Mar;130(3):321 Authors: Kouhi A, Vakili Zarch V PMID: 26878378 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1POuqwB via IFTTT

Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion.* J Laryngol Otol. 2016 Mar;130(3):318 Authors: Bakshi SS PMID: 26878377 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1POupbY via IFTTT

You can't pay me to quit: the failure of financial incentives for smoking cessation in head and neck cancer patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*You can't pay me to quit: the failure of financial incentives for smoking cessation in head and neck cancer patients.* J Laryngol Otol. 2016 Mar;130(3):278-283 Authors: Ghosh A, Philiponis G, Bewley A, Ransom ER, Mirza N Abstract OBJECTIVE: A prospective randomised study was conducted at a tertiary care hospital to evaluate the effects of financial incentives for smoking cessation targeted at a high-risk population. METHODS: Patients with a past history of head and neck cancer were voluntarily enrolled over a two-year period. They were randomised to a cash incentives or no incent...περισσότερα »

Pooled analysis of the evidence for open cavity, combined approach and reconstruction of the mastoid cavity in primary cholesteatoma surgery.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Pooled analysis of the evidence for open cavity, combined approach and reconstruction of the mastoid cavity in primary cholesteatoma surgery.* J Laryngol Otol. 2016 Mar;130(3):235-241 Authors: Harris AT, Mettias B, Lesser TH Abstract BACKGROUND: Cholesteatoma is keratinising epithelium within the middle-ear cleft or mastoid. This disease destroys the peripheral organs of balance and hearing, with possible intracranial sequelae. The management of cholesteatoma is surgical and the primary aim is to remove the disease and prevent recurrence. Secondary aims are to obtain a non-discha...περισσότερα »

Medications for Ménière's disease?

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Medications for Ménière's disease?* J Laryngol Otol. 2016 Mar;130(3):213 Authors: Youngs R, Fisher E, Hussain M, Fishman J PMID: 26878374 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1TnM547 via IFTTT

Merkel cell carcinoma of the head and neck: poorer prognosis than non-head and neck sites.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Merkel cell carcinoma of the head and neck: poorer prognosis than non-head and neck sites.* J Laryngol Otol. 2016 Feb 15;:1-5 Authors: Morand GB, Madana J, Da Silva SD, Hier MP, Mlynarek AM, Black MJ Abstract BACKGROUND: Merkel cell carcinoma is a rare, aggressive neurocutaneous malignancy. This study investigated whether patients with Merkel cell carcinoma in the head and neck had poorer outcomes than patients with Merkel cell carcinoma located elsewhere. METHODS: A retrospective study was performed of patients with Merkel cell carcinoma treated at the Jewish General Hospital in... περισσότερα »

Exercise intervention for the treatment of trismus in head and neck cancer - a prospective two-year follow-up study.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Exercise intervention for the treatment of trismus in head and neck cancer - a prospective two-year follow-up study.* Acta Oncol. 2016 Feb 15;:1-7 Authors: Pauli N, Svensson U, Karlsson T, Finizia C Abstract Background This study aims to investigate the long-term effects of structured trismus intervention in patients with head and neck cancer (HNC) and trismus in terms of mouth opening, trismus-related symptoms and health-related quality of life (HRQL). Material and methods Fifty patients with HNC to receive radiotherapy ± chemotherapy were included in this prospective study alo... περισσότερα »

Double seal technique to obliterate the eustachian tube orifice: a novel method for the treatment of recalcitrant cerebrospinal fluid leak.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Double seal technique to obliterate the eustachian tube orifice: a novel method for the treatment of recalcitrant cerebrospinal fluid leak.* J Laryngol Otol. 2016 Mar;130(3):321 Authors: Kouhi A, Vakili Zarch V PMID: 26878378 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1POuqwB via IFTTT

Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion.* J Laryngol Otol. 2016 Mar;130(3):318 Authors: Bakshi SS PMID: 26878377 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1POupbY via IFTTT

You can't pay me to quit: the failure of financial incentives for smoking cessation in head and neck cancer patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*You can't pay me to quit: the failure of financial incentives for smoking cessation in head and neck cancer patients.* J Laryngol Otol. 2016 Mar;130(3):278-283 Authors: Ghosh A, Philiponis G, Bewley A, Ransom ER, Mirza N Abstract OBJECTIVE: A prospective randomised study was conducted at a tertiary care hospital to evaluate the effects of financial incentives for smoking cessation targeted at a high-risk population. METHODS: Patients with a past history of head and neck cancer were voluntarily enrolled over a two-year period. They were randomised to a cash incentives or no incent...περισσότερα »

Lifelong Learning and Professional Development.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Lifelong Learning and Professional Development.* J Oral Maxillofac Surg. 2016 Jan 21; Authors: Carlson ER PMID: 26878363 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1TnM28k via IFTTT

Spontaneous defects between the mastoid and posterior cranial fossa.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Spontaneous defects between the mastoid and posterior cranial fossa.* Acta Otolaryngol. 2016 Feb 15;:1-4 Authors: Rereddy SK, Mattox DE Abstract Conclusions Spontaneous defects between the mastoid and the posterior cranial fossa are exceedingly rare. Patients with these lesions may have a lower BMI compared to those with middle cranial fossa encephaloceles, but are otherwise demographically similar. This study recommends repair via a transtemporal approach to allow for examination of the entire posterior face of the temporal bone. Objective To describe cases of spontaneous poste...περισσότερα »

Dual-focus versus conventional magnification endoscopy for the diagnosis of superficial squamous neoplasms in the pharynx and esophagus: a randomized trial.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Dual-focus versus conventional magnification endoscopy for the diagnosis of superficial squamous neoplasms in the pharynx and esophagus: a randomized trial.* Endoscopy. 2016 Feb 15; Authors: Goda K, Dobashi A, Yoshimura N, Aihara H, Kato M, Sumiyama K, Toyoizumi H, Kato T, Saijo H, Ikegami M, Tajiri H Abstract Background and study aims: Conventional magnification narrow-band imaging (CM-NBI) endoscopy has demonstrated high diagnostic accuracy for superficial squamous neoplasms in the pharynx and esophagus. This study aimed to evaluate the diagnostic utility of the newly develope... περισσότερα »

Factors influencing pursuit of hearing evaluation: Enhancing the health belief model with perceived burden from hearing loss on communication partners.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Factors influencing pursuit of hearing evaluation: Enhancing the health belief model with perceived burden from hearing loss on communication partners.* Int J Audiol. 2016 Feb 15;:1-10 Authors: Schulz KA, Modeste N, Lee J, Roberts R, Saunders GH, Witsell DL Abstract OBJECTIVE: There is limited application of health behavior-based theoretical models in hearing healthcare, yet other fields utilizing these models have shown their value in affecting behavior change. The health belief model (HBM) has demonstrated appropriateness for hearing research. This study assessed factors that ... περισσότερα »

Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery.* Nat Nanotechnol. 2016 Feb 15; Authors: Matsumoto Y, Nichols JW, Toh K, Nomoto T, Cabral H, Miura Y, Christie RJ, Yamada N, Ogura T, Kano MR, Matsumura Y, Nishiyama N, Yamasoba T, Bae YH, Kataoka K Abstract Enhanced permeability in tumours is thought to result from malformed vascular walls with leaky cell-to-cell junctions. This assertion is backed by studies using electron microscopy and polymer casts that show incomplete pericyte coverage of tumour vessels and the presence of interc...περισσότερα »

Intraoperative diagnostics and elimination of residual microtumours with plasmonic nanobubbles.

Alexandros G. SfakianakisστοHead and NeckΠριν από 9 δευτερόλεπτα
*Intraoperative diagnostics and elimination of residual microtumours with plasmonic nanobubbles.* Nat Nanotechnol. 2016 Feb 15; Authors: Lukianova-Hleb EY, Kim YS, Belatsarkouski I, Gillenwater AM, O'Neill BE, Lapotko DO Abstract Failure of cancer surgery to intraoperatively detect and eliminate microscopic residual disease (MRD) causes lethal recurrence and metastases, and the removal of important normal tissues causes excessive morbidity. Here, we show that a plasmonic nanobubble (PNB), a non-stationary laser pulse-activated nanoevent, intraoperatively detects and eliminates MR...περισσότερα »

Inflammatory Myofibroblastic Tumor of the Larynx:A Case Report.

Alexandros G. SfakianakisστοHead and NeckΠριν από 9 δευτερόλεπτα
*Inflammatory Myofibroblastic Tumor of the Larynx:A Case Report.* Iran J Otorhinolaryngol. 2016 Jan;28(84):79-82 Authors: Izadi F, Ghanbari H, Azizi MR, Gasembaglou S, Manteghi MJ, Ghanbari A Abstract INTRODUCTION: Inflammatory myofibroblastic pseudotumors are initially described in the lung and various extrapulmonary sites such as the orbits, palatine tonsils, ears, gingiva, pterygomaxillary space, and periodontal tissues. These tumors rarely involve the larynx and predilection to the glottis occurs in an indolent manner. CASE REPORT: This case describes a laryngeal myofibroblast...περισσότερα »

An Unusual Case of Cauda Equina Secondary to Spinal Metastasis of Thyroid Cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 9 δευτερόλεπτα
*An Unusual Case of Cauda Equina Secondary to Spinal Metastasis of Thyroid Cancer.* Iran J Otorhinolaryngol. 2016 Jan;28(84):67-71 Authors: Akhtar S, Adeel M Abstract INTRODUCTION: Cauda equina secondary to metastatic follicular thyroid cancer of the lumbosacral area is a rare entity. CASE REPORT: We report an unusual case of a 52-year-old male who presented with backache, lower limb weakness, and perianal numbness. A CT-scan of the lumbosacral area showed an enhancing mass at the L4, L5 and S1 vertebrae. Histopathology after excision revealed a metastatic thyroid cancer. Hence, ... περισσότερα »

Effects of Tonsil size on Pulmonary Function test Results after Tonsillectomy in Children.

Alexandros G. SfakianakisστοHead and NeckΠριν από 9 δευτερόλεπτα
*Effects of Tonsil size on Pulmonary Function test Results after Tonsillectomy in Children.* Iran J Otorhinolaryngol. 2016 Jan;28(84):61-6 Authors: Samareh Fekri M, Arabi Mianroodi A, Shakeri H, Khanjani N Abstract INTRODUCTION: Adenotonsillar hypertrophy is a typical cause of surgery in children. Evaluation and identification of patients as potential candidates tonsillectomy is a primary concern for otolaryngologists. This study focuses on the results of pulmonary function tests (PFTs) after tonsillectomy in children. MATERIALS AND METHODS: This cross-sectional study examined 50 ...περισσότερα »

Characterization of a migrative subpopulation of adult human nasoseptal chondrocytes with progenitor cell features and their potential for in vivo cartilage regeneration strategies.

Alexandros G. SfakianakisστοHead and NeckΠριν από 9 δευτερόλεπτα
*Characterization of a migrative subpopulation of adult human nasoseptal chondrocytes with progenitor cell features and their potential for in vivo cartilage regeneration strategies.* Cell Biosci. 2016;6:11 Authors: Elsaesser AF, Schwarz S, Joos H, Koerber L, Brenner RE, Rotter N Abstract BACKGROUND: Progenitor cells display interesting features for tissue repair and reconstruction. In the last years, such cells have been identified in different cartilage types. In this study, we isolated a migrative subpopulation of adult human nasoseptal chondrocytes with progenitor cell featur... περισσότερα »

The effects of surgical expansion of the maxillary arch and its consequences for the incisor axis

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 9 δευτερόλεπτα
Publication date: Available online 16 February 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): A. Moralis, K. Zitzmann, M. Gosau, D. Schlegel PurposeReduced transverse maxillary dental arch width may be treated either by surgically supported rapid maxillary expansion (SRME) with conservative orthodontic appliances or by means of Le Fort I osteotomy (LFIO). Both are means of transverse maxillary expansion.MethodsBoth surgical methods (SRME and LFIO) were evaluated with regard to the presurgical and postsurgical form of the maxillary dental arch and its consequences fo...περισσότερα »

Objective estimation of patient age through a new composite scale for facial aging assessment: The face - Objective assessment scale

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 9 δευτερόλεπτα
Publication date: Available online 15 February 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Simone La Padula, Barbara Hersant, Mounia SidAhmed, Jeremy Niddam, Jean Paul Meningaud Most patients requesting aesthetic rejuvenation treatment expect to look healthier and younger. Some scales for ageing assessment have been proposed, but none is focused on patient age prediction. The aim of this study was to develop and validate a new facial rating scale assessing facial ageing sign severity.One thousand Caucasian patients were included and assessed. The Rasch Model was... περισσότερα »

Diode endovascular laser treatment in venous malformations of the upper aerodigestive tract

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 9 δευτερόλεπτα
Publication date: Available online 15 February 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): François Simon, Nicolas Le Clerc, Didier Salvan, Elisabeth Sauvaget, Benoît Faucon, Michel Borsik, Philippe Herman, Annouk Bisdorff PurposeVenous malformations of the upper aerodigestive tract can cause pain, dysphagia, obstructive sleep apnea, and rarely bleeding. We studied 980-nm diode endovenous laser therapy.Material and MethodsThis is a 2007–2014 retrospective study in our vascular anomalies center. Data on patients' clinical history, polysomnography, magnetic resonan... περισσότερα »

Crescentic flap for the reconstruction of the nose after skin cancer resection

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 9 δευτερόλεπτα
Publication date: Available online 16 February 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Federica Arginelli, Attilio Carlo Salgarelli, Barbara Ferrari, Amanda Losi, Pierantonio Bellini, Cristina Magnoni PurposeNon-melanoma skin cancers are the most frequent skin tumours; in 25.5% of cases, they are reported to affect the nasal area. For an excellent surgical outcome, first of all the radical excision of the lesion is important, with appropriate margins of healthy skin in order to avoid recurrences. Moreover is important to achieve a good aesthetical result, av... περισσότερα »

Novel Approach to Securing Deep Brain Stimulation Leads: Technique and Analysis of Lead Migration, Breakage, and Surgical Infection

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 10 δευτερόλεπτα
*Background:* Fixation of the electrode during deep brain stimulation (DBS) surgery is an important aspect of the procedure. We have developed an alternative method for securing leads that utilizes a titanium hemoclip and cement. This technique is described, and the rates of complications are compared to conventional methods of securing leads. *Methods:* A total of 291 DBS operations performed by a single surgeon were retrospectively analyzed. We reviewed medical records to look for complications. We compared rates of complications based on the technique used. *Re* *sults:* 9 patien... περισσότερα »

Transient neonatal zinc deficiency

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 10 δευτερόλεπτα
A 4 month old, preterm, exclusively breastfed baby presented with a two month history of erythematous, crusted plaques on her face (A) and anogenital region, irritability, and diarrhoea. Skin swabs… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1SuS5Ys via IFTTT

A review of trabecular bone functional adaptation: what have we learned from trabecular analyses in extant hominoids and what can we apply to fossils?

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 10 δευτερόλεπτα
Abstract Many of the unresolved debates in palaeoanthropology regarding evolution of particular locomotor or manipulative behaviours are founded in differing opinions about the functional significance of the preserved external fossil morphology. However, the plasticity of internal bone morphology, and particularly trabecular bone, allowing it to respond to mechanical loading during life means that it can… Continue reading A review of trabecular bone functional adaptation: what have we learned from trabecular analyses in extant hominoids and what can we apply to fossils?

Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 10 δευτερόλεπτα
Abstract Autophagic (type II) cell death has been suggested to play pathogenetic roles in cerebral ischemia. Growth arrest and DNA damage response 45b (Gadd45b) has been shown to protect against rat brain ischemia injury through inhibiting apoptosis. However, the relationship between Gadd45b and autophagy in cerebral ischemia/reperfusion (I/R) injury remains uncertain. The aim of this… Continue reading Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury

Objective estimation of patient age through a new composite scale for facial aging assessment: The face – Objective assessment scale

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 10 δευτερόλεπτα
Publication date: Available online 15 February 2016 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Simone La Padula, Barbara Hersant, Mounia SidAhmed, Jeremy Niddam, Jean Paul Meningaud Most patients requesting aesthetic rejuvenation treatment expect to look healthier and younger. Some scales for ageing assessment have been proposed, but none is focused on patient age prediction. The aim of… Continue reading Objective estimation of patient age through a new composite scale for facial aging assessment: The face – Objective assessment scale

A Study to Compare the Efficacy and Safety of Obinutuzumab + Venetoclax versus Obinutuzumab + Chlorambucil in Patients With Chronic Lymphocytic Leukemia (CLL14)

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 10 δευτερόλεπτα
Oncol Res Treat 2016;39:69-71 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1LrmjnR via IFTTT

Abdominal discomfort with an alarming scan

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 10 δευτερόλεπτα
A 74 year old woman presented after two weeks of rigors and abdominal discomfort. She had raised inflammatory markers and cholestatic liver function tests. After unhelpful ultrasound and magnetic… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1SuRsOB via IFTTT

The effects of surgical expansion of the maxillary arch and its consequences for the incisor axis

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 10 δευτερόλεπτα
Publication date: Available online 16 February 2016 Source:Journal of Cranio-Maxillofacial Surgery Author(s): A. Moralis, K. Zitzmann, M. Gosau, D. Schlegel PurposeReduced transverse maxillary dental arch width may be treated either by surgically supported rapid maxillary expansion (SRME) with conservative orthodontic appliances or by means of Le Fort I osteotomy (LFIO). Both are means of transverse… Continue reading The effects of surgical expansion of the maxillary arch and its consequences for the incisor axis

Diode endovascular laser treatment in venous malformations of the upper aerodigestive tract

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 10 δευτερόλεπτα
Publication date: Available online 15 February 2016 Source:Journal of Cranio-Maxillofacial Surgery Author(s): François Simon, Nicolas Le Clerc, Didier Salvan, Elisabeth Sauvaget, Benoît Faucon, Michel Borsik, Philippe Herman, Annouk Bisdorff PurposeVenous malformations of the upper aerodigestive tract can cause pain, dysphagia, obstructive sleep apnea, and rarely bleeding. We studied 980-nm diode endovenous laser therapy.Material and MethodsThis… Continue reading Diode endovascular laser treatment in venous malformations of the upper aerodigestive tract

Crescentic flap for the reconstruction of the nose after skin cancer resection

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 10 δευτερόλεπτα
Publication date: Available online 16 February 2016 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Federica Arginelli, Attilio Carlo Salgarelli, Barbara Ferrari, Amanda Losi, Pierantonio Bellini, Cristina Magnoni PurposeNon-melanoma skin cancers are the most frequent skin tumours; in 25.5% of cases, they are reported to affect the nasal area. For an excellent surgical outcome, first of all the… Continue reading Crescentic flap for the reconstruction of the nose after skin cancer resection

Lateral Tarsotomy: A Practical Alternative to Lateral Canthotomy to Increase Orbital Access

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 10 δευτερόλεπτα
Publication date: Available online 16 February 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Hany A. Emam, Mark R. Stevens, Peter E. Larsen, Courtney A. Jatana ObjectiveTransconjunctival approach to the lower 1/3 of the orbit is commonly used to avoid transcutaneous incisions when surgical access is needed. A lateral canthotomy is used… Continue reading Lateral Tarsotomy: A Practical Alternative to Lateral Canthotomy to Increase Orbital Access

Pharmacologic treatment for postviral olfactory dysfunction: Oral corticosteroids, local injections of corticosteroids, zinc sulfate, alpha lipoic acid, caroverine, vitamin A, Ginkgo biloba, and minocycline

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Pharmacologic treatment for postviral olfactory dysfunction: a systematic review: Background Postviral olfactory dysfunction (PVOD) is the most common cause of olfactory dysfunction. Several treatments have been presented in the literature. The objective of this study is to systematically review the existing literature on the effectiveness of pharmacologic treatments for PVOD. Methods We performed a literature search of PubMed, Ovid, and ScienceDirect from 1966 to 2014. Inclusion criteria included English-language articles containing original data on pharmacologic treatment of PVOD... περισσότερα »

Budesonide nasal irrigations in patients with chronic rhinosinusitis post endoscopic sinus surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Safety analysis of long-term budesonide nasal irrigations in patients with chronic rhinosinusitis post endoscopic sinus surgery: Background Although the safety of topical nasal steroids is well established for nasal spray forms, data regarding the safety of steroid irrigations is limited. We studied the effect of long-term budesonide nasal irrigations (>6 months) on hypothalamic-pituitary-adrenal axis (HPAA) function and intraocular pressure (IOP) in patients post–endoscopic sinus surgery. Methods This was retrospective case series. Adrenal function was assessed by using the high-do... περισσότερα »

Outcomes of revision endoscopic modified Lothrop procedure

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Outcomes of revision endoscopic modified Lothrop procedure: Background Endoscopic modified Lothrop procedure (EMLP) is used to treat patients who fail conventional sinus surgery. The failure rate of a primary EMLP is reported to be between 5% and 32%. The failure rate of revision EMLP has not been reported. We present our institutions data regarding the outcome of patients requiring revision EMLP. Methods Data was collected prospectively. Patients undergoing primary EMLP between January 2001 and December 2013 with a minimum follow-up of 6 months were included. Information related to...περισσότερα »

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis Executive Summary

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
International Consensus Statement on Allergy and Rhinology: Rhinosinusitis Executive Summary: Background The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). This executive summary consolidates the findings of the ICAR:RS document. Metho...περισσότερα »

Immunoglobulin E plasma cells that are elevated in the upper airway mucosa of nonatopic patients with chronic rhinosinusitis without nasal polyps

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Characterization of immunoglobulin E plasma cells that are elevated in the upper airway mucosa of nonatopic patients with chronic rhinosinusitis without nasal polyps: Background The immunologic mechanisms driving inflammation in the upper airways of patients with chronic rhinosinusitis (CRS) are poorly understood. Previous studies have shown that B cells and immunoglobulin E (IgE) levels are elevated in the nasal tissue of patients with atopic chronic rhinosinusitis without nasal polyps (CRSsNP). However, less is known regarding B cell subsets and IgE-producing plasmablasts in nona... περισσότερα »

The endoscopic transseptal approach for choanal atresia repair

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
The endoscopic transseptal approach for choanal atresia repair: Background There are many standard repair options for choanal atresia including puncture, dilatation and drilling of the atretic plate. Most of these techniques involve postoperative stenting, which may promote granulation and scarring, with possible progression to restenosis. This article describes a novel approach for choanal atresia repair without postoperative stenting. Methods This article describes our experience with this choanal atresia repair technique utilized in 16 pediatric patients and 1 adult patient acros... περισσότερα »

Sinus irrigations before and after sinus surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Cadaveric validation study of computational fluid dynamics model of sinus irrigations before and after sinus surgery: Background Investigations into the distribution of sinus irrigations have been limited by labor-intensive methodologies that do not capture the full dynamics of irrigation flow. The purpose of this study was to validate the accuracy of a computational fluid dynamics (CFD) model for sinonasal irrigations through a cadaveric experiment. Methods Endoscopic sinus surgery was performed on 2 fresh cadavers to open all 8 sinuses, including a Draf III procedure for cadaver 1... περισσότερα »

Light-Activated Sealing of Acellular Nerve Allografts following Nerve Gap Injury

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Light-Activated Sealing of Acellular Nerve Allografts following Nerve Gap Injury: J reconstr Microsurg DOI: 10.1055/s-0035-1571247 Introduction Photochemical tissue bonding (PTB) uses visible light to create sutureless, watertight bonds between two apposed tissue surfaces stained with photoactive dye. In phase 1 of this two-phase study, nerve gaps repaired with bonded isografts were superior to sutured isografts. When autograft demand exceeds supply, acellular nerve allograft (ANA) is an alternative although outcomes are typically inferior. This study assesses the efficacy of PTB ... περισσότερα »

Oral Biomarkers in Exercise-induced Neuroplasticity in Parkinson's Disease

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Oral Biomarkers in Exercise-induced Neuroplasticity in Parkinson's Disease: Abstract In this paper we review candidate biomarkers for Parkinson's disease (PD) in oral cavity, potential of oral biomarkers as markers of neuroplasticity, and literature on effects of exercise on oral cavity biomarkers in PD. We first describe how pathophysiological pathways of PD may be transduced from brain stem and ganglia to oral cavity through the autonomic nervous system or transduced by a reverse path. Next we describe effects of exercise in PD and potential impact on oral cavity. We propose that ...περισσότερα »

Base of tongue and tonsil carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Evidence for a stabilization of incidence rates for base of tongue and tonsil carcinoma in the U.S. white population: Increasing age-standardized incidence rates (ASIRs) for oropharyngeal (OP) squamous cell carcinomas (SCC), have been reported using cancer registries in many western countries, although the time periods and factors involved differ [1–4]. In East Germany, however, ASIRs for OPSCC did not increase after 2008 (through 2011) for males [4]. It was also noted [4] that previously rising ASIRs had stabilized from 2000–2006 to 2007–2012 in Stockholm County, Sweden, for SCC of...περισσότερα »

Infiltration of T cell subsets during oral carcinogenesis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Infiltration of T cell subsets during oral carcinogenesis: *Birva Brahmbhatt, Hemangini Vora, Birwa Shah* Indian Journal of Oral Sciences 2016 7(1):28-41 Introduction: Alteration of local T cell immune response is often observed in oral squamous cell carcinoma (OSCC). However, their role in premalignant conditions is still unclear. This study has been planned to observe T cell subsets during oral carcinogenesis. Patients and Methods: Cytotoxic, helper, and regulatory T cells infiltrated in tissue of hyperplasia (n = 23), dysplasia (n = 20), and OSCC (n = 100) patients were eval... περισσότερα »

Brown tumor of mandible in association with primary hyperparathyroidism

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Brown tumor of mandible in association with primary hyperparathyroidism: *KR Indumati Rao, NS Priya, Kavita Rao, DP Ashwin* Indian Journal of Oral Sciences 2016 7(1):54-58 Brown tumor is considered a reparative cellular event rather than a true neoplasm. The presentation of reparative growths mimicking clinically as neoplasms can be an alarming situation to the clinician. It is also important to differentiate brown tumor from other giant cell group of lesions based upon history and biochemical findings. We are reporting a case of brown tumor of the mandible in a patient who was ... περισσότερα »

Crescentic flap for the reconstruction of the nose after skin cancer resection

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Crescentic flap for the reconstruction of the nose after skin cancer resection: Non-melanoma skin cancers are the most frequent skin tumours; in 25.5% of cases, they are reported to affect the nasal area. For an excellent surgical outcome, first of all the radical excision of the lesion is important, with appropriate margins of healthy skin in order to avoid recurrences. Moreover is important to achieve a good aesthetical result, avoiding distortion of the aesthetic units and preserving their functions.

Facial aging assessment: The face - Objective assessment scale

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Objective estimation of patient age through a new composite scale for facial aging assessment: The face - Objective assessment scale: Most patients requesting aesthetic rejuvenation treatment expect to look healthier and younger. Some scales for ageing assessment have been proposed, but none is focused on patient age prediction. The aim of this study was to develop and validate a new facial rating scale assessing facial ageing sign severity.One thousand Caucasian patients were included and assessed. The Rasch Model was used as part of the validation process. A score was attributed t...περισσότερα »

Oropharyngeal Melanoma

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
A rare case of oropharyngeal melanoma: Case report and brief review of literature: *Amitabh Jena, Alamuri Ramesh, Rashmi Patnayak, Nandyala Rukmangadha, Banoth Manilal, AY Lakshmi* Indian Journal of Oral Sciences 2016 7(1):63-66 Mucosal melanomas are rare compared with the cutaneous melanomas. They present with advanced stage and are known to have a poor outcome in comparison to their cutaneous counterparts. Mucosal melanomas constitute about 1.3% of all melanomas. The most common site of mucosal melanomas is the head and neck region. In oropharynx, 95% of all malignancies are ...περισσότερα »

Granular cell tumor of tongue

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Granular cell tumor of tongue: Report of two cases: *D Gopinath, VT Beena, SK Padmakumar, G Sugirtharaj* Indian Journal of Oral Sciences 2016 7(1):47-50 Granular cell tumor (GCT), also known as Abrikossoff tumor, is a relatively uncommon benign neoplasm, which is more commonly found in females in the fourth to sixth decades of life. GCTs can affect any organ or region of the body. Most GCTs occur in the head and neck region, especially in the tongue, cheek mucosa, and palate. Clinically, benign GCT manifests as a nodular lesion that is generally asymptomatic and solitary, althou... περισσότερα »

Narrow-band imaging: Breakthrough at the forefront of medicine

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Narrow-band imaging: Breakthrough at the forefront of medicine: *Geetha Kamath, Ingita Chatterjee, HS Srikanth, Medha Babshet* Indian Journal of Oral Sciences 2016 7(1):7-10 The most common head and neck malignancy is squamous cell carcinoma. The result of surgical and oncological treatment of large tumors leads to a significant mutilation of the affected individual. Early detection of tumors is, therefore, one of the most important factors of treatment success. Efforts to achieve the earliest detection of malignant disease have led to the development of new endoscopic examinati... περισσότερα »

Malignant lymphomas represent approximately 5% of all malignant neoplasms of the head and neck : Classical Hodgkin's lymphoma (mixed cellular variant)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Classical Hodgkin's lymphoma (mixed cellular variant): *Sumith Gunawardane, Primali Jayasuriya* Indian Journal of Oral Sciences 2016 7(1):59-62 Malignant lymphomas represent approximately 5% of all malignant neoplasms of the head and neck. They are divided into two subgroups, Hodgkin's lymphomas (HLs) and non-HL. This is a case report of a 23-year-old female, who presented with multiple nontender lumps on the right posterior triangle of the neck of 4 months duration. She was diagnosed with, “Classical Hodgkin's lymphoma” (mixed cellularity type) of the head and neck region, whi...περισσότερα »

The child and adolescent with HIV in resource poor countries

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
The child and adolescent with HIV in resource poor countries: Although sub-Saharan Africa caries the burden of paediatric and adult HIV/AIDS infections, the epidemic is spreading most rapidly in the Middle East and North Africa Region where between 2005 and 2013, AIDS-related deaths increased by 66% in comparison with a worldwide fall of 35%. For the first time, in 2011, more than half of people in need of antiretroviral drugs were receiving them, with coverage reaching 54%; yet only 28% of children have access to HIV treatment. This review sought to provide an update of paediatric... περισσότερα »

Oral epithelial cells and their interactions with HIV-1

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
Oral epithelial cells and their interactions with HIV-1: As the AIDS pandemic has continued, our understanding of the events that occur during the entry and infection of conventional, susceptible cells has increased dramatically, leading to the development of control therapies for HIV-infected individuals. However, an ongoing hole in our understanding is how HIV crosses the mucosal barriers to gain access to permissive cells, despite how important this information would be in developing successful vaccines and other preventative measures such as topical anti-HIV microbicides. In pa... περισσότερα »

Lateral Tarsotomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
: A Practical Alternative to Lateral Canthotomy to Increase Orbital Access via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 16 February 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Hany A. Emam, Mark R. Stevens, Peter E. Larsen, Courtney A. Jatana ObjectiveTransconjunctival approach to the lower 1/3 of the orbit is commonly used to avoid transcutaneous incisions when surgical access is needed. A lateral canthotomy is used in conjunction with this approach if increased lateral exposure is req... περισσότερα »

Immigrants’ oral health literacy and participation in oral health care

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
Brazilian immigrants’ oral health literacy and participation in oral health care in Canada: Abstract BackgroundInadequate functional health literacy is a common problem in immigrant populations. The aim of this study was to investigate the association between oral (dental) health literacy (OHL) and participation in oral health care among Brazilian immigrants in Toronto, Ontario, Canada. MethodsThe study used a cross-sectional design and a convenience sample of 101 Brazilian immigrants selected through the snowball sampling technique. Data were analyzed using descriptive statist... περισσότερα »

Electrode array-eluted dexamethasone protects against electrode insertion trauma induced hearing and hair cell losses, damage to neural elements, increases in impedance and fibrosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
: A dose response study via Hearing Research Publication date: Available online 15 February 2016 *Source:*Hearing Research Author(s): Esperanza Bas, Jorge Bohorquez, Stefania Goncalves, Enrique Perez, Christine T. Dinh, Carolyn Garnham, Roland Hessler, Adrien A. Eshraghi, Thomas R. Van De Water We evaluated the effects of dexamethasone base (DXMb) containing electrode arrays in a guinea pig model of cochlear implantation to determine if eluted DXMb could protect the cochlea against electrode insertion trauma (EIT)-induced: 1) loss of hair cells; 2) disruption of neural elements; 3) in... περισσότερα »

Predicting three-month and 12-month post-fitting real-world hearing-aid outcome using pre-fitting acceptable noise level (ANL)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Predicting three-month and 12-month post-fitting real-world hearing-aid outcome using pre-fitting acceptable noise level (ANL): 10.3109/14992027.2015.1120892<br>Yu-Hsiang Wu Abstract *Objective*: Determine the extent to which pre-fitting acceptable noise level (ANL), with or without other predictors such as hearing-aid experience, can predict real-world hearing-aid outcomes at three and 12 months post-fitting. *Design*: ANLs were measured before hearing-aid fitting. Post-fitting outcome was assessed using the international outcome inventory for hearing aids (IOI-HA) and a hearin... περισσότερα »

Vagus Nerve Stimulation For Tinnitus

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Vagus Nerve Stimulation For Tinnitus: ------------------------------ People suffering from severe tinnitus have a hard time finding helpful therapies. Now, a new treatment using vagus nerve stimulation for tinnitus relief is showing promising results for many people with this frustrating and debilitating condition. Tinnitus is a medical condition in which a person hears ringing, whooshing, or buzzing sounds inside their head and ears. Many people experience short episodes of tinnitus symptoms from time to time. People with bad cases of tinnitus hear these sounds all the time, cau... περισσότερα »

Open Versus Closed Hearing-Aid Fittings

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Open Versus Closed Hearing-Aid Fittings: A Literature Review of Both Fitting Approaches: One of the main issues in hearing-aid fittings is the abnormal perception of the user’s own voice as too loud, "boomy," or "hollow." This phenomenon known as the occlusion effect be reduced by large vents in the earmolds or by open-fit hearing aids. This review provides an overview of publications related to open and closed hearing-aid fittings. First, the occlusion effect and its consequences for perception while using hearing aids are described. Then, the advantages and disadvantages of open ... περισσότερα »

Emotional videos on postural control in children

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Effects of via Gait &amp; Posture Publication date: March 2016 *Source:*Gait &amp; Posture, Volume 45 Author(s): Arthur de Freitas Brandão, Estelle Palluel, Isabelle Olivier, Vincent Nougier The link between emotions and postural control has been rather unexplored in children. The objective of the present study was to establish whether the projection of pleasant and unpleasant videos with similar arousal would lead to specific postural responses such as postural freezing, aversive or appetitive behaviours as a function of age. We hypothesized that postural sway would similarly increase with ...περισσότερα »

Surgery for refractory benign paroxysmal positional vertigo (BPPV)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
Bilateral posterior semi-circular canal obliteration surgery for refractory benign paroxysmal positional vertigo (BPPV) in three patients: Abstract Benign paroxysmal positional vertigo (BPPV) is a common cause of peripheral vestibular disorder1 characterised by a short lasting rotatory vertigo triggered by movement of the head. Unilateral posterior canal plugging has become an accepted, if uncommonly used, method of treating intractable cases. However there is very limited experience of bilateral posterior canal plugging. When the current series of cases began, there were no cases ... περισσότερα »

Acute unilateral sensorineural hearing loss associated with anabolic steroids and polycythaemia: case report

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
Clinical RecordsAcute unilateral sensorineural hearing loss associated with anabolic steroids and polycythaemia: case reportT Tikkaa1 c1, N Mistrya1 and A Janjuaa1 a1 Department of ENT, Birmingham Heartlands (Teaching) Hospital, UK Abstract Background: Unilateral sudden sensorineural hearing loss due to an infarct in the vertebrobasilar system has been widely reported. Most patients have a background of traditional coronary risk factors related to these cerebrovascular episodes. Case report: A 32-year-old male, a regular user of anabolic steroids, presented to the emergency department...περισσότερα »

Modified approach to powered endoscopic dacryocystorhinostomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Main ArticlesModified approach to powered endoscopic dacryocystorhinostomyT N Janakirama1, N Suria2 c1 and S B Sharmaa1 a1 Department of Otolaryngology, Royal Pearl Hospital, Tiruchirapalli, Tamil Nadu a2 Department of ENT, Gujarat Medical Education and Research Society (‘GMERS’) Medical College, Gandhinagar, India Abstract Objective: This paper presents modifications to powered endoscopic dacryocystorhinostomy without stenting for the management of acquired nasolacrimal duct obstruction. Study design: A retrospective, non-randomised review. Method: A total of 105 patients with epiphor... περισσότερα »

Primary tumour characteristics predict the invasiveness of lymph node metastases in papillary thyroid carcinoma patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Main ArticlesPrimary tumour characteristics predict the invasiveness of lymph node metastases in papillary thyroid carcinoma patientsH S Leea1, C Parka1, S W Kima1, J W Songa1, B K Chuna2, T J Parka3, J C Honga4 and K D Leea1 c1 a1 Department of Otolaryngology – Head and Neck Surgery, Kosin University College of Medicine, Busan, Korea a2 Department of Pathology, Kosin University College of Medicine, Busan, Korea a3 Department of Otolaryngology – Head and Neck Surgery, Maryknoll Medical Center, Busan, Korea a4 Department of Otolaryngology – Head and Neck Surgery, Dong-A University Col... περισσότερα »

Facial nerve management in jugular paraganglioma surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Review ArticlesFacial nerve management in jugular paraganglioma surgery: a literature reviewH Odata1 c1, S-H Shina3, M A Odata2 and F Alzoubia1 a1 Division of Otolaryngology, Department of Special Surgery, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan a2 Department of Special Surgery, King Hussein Medical Centre, Royal Medical Services of Jordan, Amman, Jordan a3 Department of Otorhinolaryngology – Head and Neck Surgery, School of Medicine, Ewha Womans University, Seoul, Korea Abstract Objective: This literature review analysed facial nerve management ... περισσότερα »

A review of trabecular bone functional adaptation: what have we learned from trabecular analyses in extant hominoids and what can we apply to fossils?

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Abstract Many of the unresolved debates in palaeoanthropology regarding evolution of particular locomotor or manipulative behaviours are founded in differing opinions about the functional significance of the preserved external fossil morphology. However, the plasticity of internal bone morphology, and particularly trabecular bone, allowing it to respond to mechanical loading during life means that it can reveal greater insight into how a bone or joint was used during an individual's lifetime. Analyses of trabecular bone have been commonplace for several decades in a human clinical ... περισσότερα »

Healthcare provider contact for children with symptoms of sleep-disordered breathing: a population survey

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Main ArticlesHealthcare provider contact for children with symptoms of sleep-disordered breathing: a population surveyG Gudnadottira1, A Ehnhagea2 a3, M Bendea4, M Anderssona5, A Cervina7, L O Cardella6and J Hellgrena1 c1 a1 Department of Otorhinolaryngology, Institution for Clinical Sciences, Sahlgrenska Academy at Gothenburg University, Sahlgrenska University Hospital, Gothenburg, Sweden a2 Department of Clinical Sciences, Intervention and Technology, Division Otorhinolaryngology, Karolinska Institutet, Sweden a3 Nacka Närsjukhus Proxima, Stockholm, Sweden a4 Department of Otorhinolar... περισσότερα »

Short-term weight gain after adenotonsillectomy in children with obstructive sleep apnoea: systematic review

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Review ArticlesShort-term weight gain after adenotonsillectomy in children with obstructive sleep apnoea: systematic reviewM Vana1, I Khana1 and S S M Hussaina1 c1 a1 Department of Otorhinolaryngology, Head and Neck Surgery, Ninewells Hospital and University of Dundee Medical School, Scotland, UK Abstract Background: Children with obstructive sleep apnoea commonly undergo adenotonsillectomy as first-line surgical treatment. This paper aimed to investigate whether this intervention was associated with weight gain after surgery in the paediatric population with obstructive sleep apnoea.... περισσότερα »

Does the continuation of warfarin change management outcomes in epistaxis patients?

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Main ArticlesDoes the continuation of warfarin change management outcomes in epistaxis patients?S Bolaa1 c1, R Marsha1, S Bragginsa1, C Pottera1 and S Hickeya1 a1 Otolaryngology Department, Torbay Hospital, South Devon Healthcare Trust, Torquay, UK Abstract Objective: This study aimed to compare management, readmission rates and length of in-patient stay amongst warfarinised and non-warfarinised patients to ascertain future treatment protocols. Methods: A 12-month retrospective review was conducted of ENT epistaxis admissions. Admission details such as length of in-patient stay, clott... περισσότερα »

Tracheal agenesis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Clinical RecordsTracheal agenesis, a frightening scenarioH Mohammeda1 c1, K Westa1, J Bewicka1 and M Wicksteada1 a1 ENT Department, Norfolk and Norwich University Hospital, Norwich, UK Abstract Objective: This paper discusses three cases of tracheal agenesis that presented within a six-week period to the Norfolk and Norwich University Hospital. By reviewing the available literature on tracheal agenesis, the report aims to outline a protocol for future prenatal and postnatal management. Methods: A case series and a literature review. Results: Three cases of tracheal agenesis presented i...περισσότερα »

Effect of intranasal steroids on rhinosinusitis after radiotherapy for nasopharyngeal carcinoma: clinical study

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Main ArticlesEffect of intranasal steroids on rhinosinusitis after radiotherapy for nasopharyngeal carcinoma: clinical studyS Fenga1, Y Fana1 c1, Z Lianga2, G Yanga2, Z Liaoa1 and L Guoa1 a1 Department of Otolaryngology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China a2 Department of Radiation Oncology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China Abstract Objective: Post-irradiation rhinosinusitis is one of the most common untoward side effects in patients with nasopharyngeal carcinoma. This study aimed to evaluate the effect of fluticasone p... περισσότερα »

Simulation-based otolaryngology – head and neck surgery boot camp

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Main ArticlesSimulation-based otolaryngology – head and neck surgery boot camp: ‘how I do it’C J China1, C A China2, K Rotha3, B W Rotenberga3 and K Funga3 c1 a1 Department of Otolaryngology – Head &amp; Neck Surgery, University of Toronto, Ontario, Canada a2 Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada a3 Department of Otolaryngology – Head &amp; Neck Surgery, Western University, London, Ontario, Canada Abstract Background: In otolaryngology, surgical emergencies can occur at any time. An annual surgical training camp (or ‘boot camp’) offers junior r... περισσότερα »

Knowledge and Attitudes Towards Human Papillomavirus (HPV) Among Academic and Community Physicians in Mangalore, India

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 32 δευτερόλεπτα
Abstract Cervical cancer is the most common cancer found in Indian women. Two human papillomavirus (HPV) vaccines were approved for use in India in 2006; however, neither has become readily accepted. Physician attitudes and recommendations are crucial in the uptake of HPV vaccines among adolescent women in the USA; thus, we ought to investigate provider attitudes and practices related to HPV vaccination in India via a survey administered to 210 Indian physicians. Of the 210 physicians, 46 % were community physicians and 54 % were academic physicians. The correct response to HPV kn... περισσότερα »

A review of trabecular bone functional adaptation: what have we learned from trabecular analyses in extant hominoids and what can we apply to fossils?

Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 35 δευτερόλεπτα
Abstract Many of the unresolved debates in palaeoanthropology regarding evolution of particular locomotor or manipulative behaviours are founded in differing opinions about the functional significance of the preserved external fossil morphology. However, the plasticity of internal bone morphology, and particularly trabecular bone, allowing it to respond to mechanical loading during life means that it can reveal greater insight into how a bone or joint was used during an individual's lifetime. Analyses of trabecular bone have been commonplace for several decades in a human clinical ... περισσότερα »

Does the intravenous administration of frusemide reduce endolymphatic hydrops?

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 36 δευτερόλεπτα
Main ArticlesDoes the intravenous administration of frusemide reduce endolymphatic hydrops?F Fiorinoa1 c1, B Mattellinia2, M Ventoa2, L Mazzocchina3, L Bianconia4 and F B Pizzinia5 a1 Department of Otolaryngology, Ospedale Mater Salutis – Azienda Unita Locale Socio Sanitaria 21, Legnago, Italy a2 Department of Otolaryngology, Ospedale di Fidenza, Azienda Unità Sanitaria Parma, Italy a3 Department of Otolaryngology, Ospedale Sacro Cuore, Negrar, Italy a4 Department of Otolaryngology, Ospedale Civile Maggiore – Azienda Ospedaliera Universitaria Integrata Verona, Italy a5 Department of Ne... περισσότερα »

Effects of emotional videos on postural control in children

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα
Publication date: March 2016 *Source:*Gait &amp; Posture, Volume 45 Author(s): Arthur de Freitas Brandão, Estelle Palluel, Isabelle Olivier, Vincent Nougier The link between emotions and postural control has been rather unexplored in children. The objective of the present study was to establish whether the projection of pleasant and unpleasant videos with similar arousal would lead to specific postural responses such as postural freezing, aversive or appetitive behaviours as a function of age. We hypothesized that postural sway would similarly increase with the viewing of high arousal v...περισσότερα »

Global Personal 3D Printer Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα
Global Personal 3D Printer Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad i... from Infection via ola Kala on Inoreader http://ift.tt/1TnusBi via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PBSEMG via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.t... περισσότερα »

Global CD Copying Machine Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα
Global CD Copying Machine Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad in... from Infection via ola Kala on Inoreader http://ift.tt/1mELaOk via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PBSC7n via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.t... περισσότερα »

Global Copying Apparatus Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα
Global Copying Apparatus Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad int... from Infection via ola Kala on Inoreader http://ift.tt/1Tnuucs via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SuC2dk via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.t... περισσότερα »

Global DE-Demi Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα
Global DE-Demi Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad introduction ... from Infection via ola Kala on Inoreader http://ift.tt/1mELaxW via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PBSC7j via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.t... περισσότερα »

Global Label printer Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα
Global Label printer Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad introdu... from Infection via ola Kala on Inoreader http://ift.tt/1TnutVY via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SuBZyd via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.... περισσότερα »

Ischemic postconditioning influences electron transport chain protein turnover in Langendorff-perfused rat hearts

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα
Ischemia postconditioning (IPo) is a promising strategy in reducing myocardial ischemia reperfusion (I/R) injury (MIRI), but its specific molecular mechanism is incompletely understood. Langendorff-perfused isolated rat hearts were subjected to global I/R and received IPo in the absence or presence of the mitochondrial ATP-sensitive potassium channel (mitoKATP) blocker 5-hydroxydecanoate (5-HD). Myocardial mitochondria were extracted and mitochondrial comparative proteomics was analyzed. IPo significantly reduces post-ischemic myocardial infarction and improved cardiac function in... περισσότερα »

A pan-cancer analysis of prognostic genes

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα
Numerous studies have identified prognostic genes in individual cancers, but a thorough pan-cancer analysis has not been performed. In addition, previous studies have mostly used microarray data instead of RNA-SEQ, and have not published comprehensive lists of associations with survival. Using recently available RNA-SEQ and clinical data from The Cancer Genome Atlas for 6,495 patients, we have investigated every annotated and expressed gene's association with survival across 16 cancer types. The most statistically significant harmful and protective genes were not shared across can...περισσότερα »

α-Phosphonovinyl Arylsulfonates: An Attractive Partner for the Synthesis of α-Substituted Vinylphosphonates through Palladium-Catalyzed Suzuki Reactions

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα
Abstract It has been demonstrated that a variety of α-phosphonovinyl arylsulfonates with electron-neutral, -donating, and -withdrawing groups on the phenyl ring could be conveniently and efficiently prepared. In the presence of a Pd(OAc)2/SPhos-based catalyst, various organoboron compounds could be employed as the nucleophilic coupling partners, such as organoboronic acids, boronate esters, and organotrifluoroborates. The newly developed *O*-centered electrophiles could couple with a multitude of aryl, heteroaryl, and alkylboron reagents, to give α-substituted vinylphosphonates in ...περισσότερα »

Application of Deep Eutectic Solvents in Promiscuous Lipase-Catalysed Aldol Reactions

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα
Abstract The application of deep eutectic solvents has been demonstrated for the first time in promiscuous lipase-catalysed aldol reactions. The model reaction between 4-nitrobenzaldehyde and acetone was examined in depth, with excellent compatibility being found between porcine pancreas lipase and choline chloride/glycerol mixtures for the formation of the aldol product in high yields. The system was compatible with a series of aromatic aldehydes and ketones including acetone, cyclopentanone and cyclohexanone. In some cases, the corresponding α,β-unsaturated carbonyl compounds wer...περισσότερα »

Risk of infection following colonization with carbapenem-resistant Enterobactericeae: A systematic review

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 36 δευτερόλεπτα
Publication date: Available online 15 February 2016 *Source:*American Journal of Infection Control Author(s): Jessica Tischendorf, Rafael Almeida de Avila, Nasia Safdar BackgroundCarbapenem-resistant Enterobacteriaceae (CRE) have emerged as important health care-associated pathogens. Colonization precedes infection but the risk of developing infection amongst those colonized with CRE is not clear.MethodsWe searched multiple databases for studies reporting rates of CRE-colonized patients subsequently developing infection.ResultsTen studies fulfilled our inclusion criteria, including 1...περισσότερα »

Global Personal 3D Printer Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 36 δευτερόλεπτα
Global Personal 3D Printer Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad i... from Infection via ola Kala on Inoreader http://ift.tt/1TnusBi via IFTTT

Global CD Copying Machine Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 36 δευτερόλεπτα
Global CD Copying Machine Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad in... from Infection via ola Kala on Inoreader http://ift.tt/1mELaOk via IFTTT

Sublingual immunotherapy in patients with house dust mite allergic rhinitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 36 δευτερόλεπτα
Main ArticlesSublingual immunotherapy in patients with house dust mite allergic rhinitis: prospective study of clinical outcomes over a two-year periodJ Y Soha1, M Thalayasingama2, S Onga3, E X L Looa4, L P Sheka1 c1 and S S Chaoa3 a1 University Children's Medical Institute, National University Health Systems, Singapore a2 Department of Paediatrics, International Medical University Clinical School, Seremban, Malaysia a3 Department of Otolaryngology Head and Neck Surgery, National University Health Systems, Singapore a4 Singapore Institute for Clinical Sciences, Agency for Science, Te... περισσότερα »

Comparison of the protective effects of intratympanic dexamethasone and methylprednisolone against cisplatin-induced ototoxicity

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 37 δευτερόλεπτα
Main ArticlesComparison of the protective effects of intratympanic dexamethasone and methylprednisolone against cisplatin-induced ototoxicityH E Özela1 c1, F Özdoğana1, S G Gürgena2, E Esena1, S Gença1 and A Selçuka1 a1 Department of Otolaryngology, Kocaeli Derince Research and Training Hospital, Kocaeli, Turkey a2 Department of Histology and Embryology, Celal Bayar University School of Vocational Health Service, Manisa, Turkey Abstract Objective: This study aimed to compare the efficacies of intratympanic dexamethasone and methylprednisolone in preventing in cisplatin-induced ototoxi... περισσότερα »

Survival outcomes after surgical resection of pulmonary metastases of head and neck tumours

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Main ArticlesSurvival outcomes after surgical resection of pulmonary metastases of head and neck tumoursS Hosokawaa1 c1, K Funaia2, K Sugiyamaa1, G Takahashia1, J Okamuraa1, Y Takizawaa1, T Yamatodania1 and H Minetaa1 a1 Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Japan a2 First Department of Surgery, Hamamatsu University School of Medicine, Japan Abstract Background: There is limited information available regarding the benefits and outcomes of resection of pulmonary metastases arising from head and neck cancers. Methods: A retrosp... περισσότερα »

Double seal technique to obliterate the eustachian tube orifice: a novel method for the treatment of recalcitrant cerebrospinal fluid leak

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Double seal technique to obliterate the eustachian tube orifice: a novel method for the treatment of recalcitrant cerebrospinal fluid leak: Letter A Kouhi, V Vakili Zarch, The Journal of Laryngology &amp; Otology, Volume 130 Issue 03, pp 321-321 Abstract

Endoscopic vocal fold injection using a 25-gauge butterfly needle

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Endoscopic vocal fold injection using a 25-gauge butterfly needle: Rapid Communication M A Buchanan, F Riffat, C E Palme The Journal of Laryngology &amp; Otology,FirstView Article(s), 3 pages Abstract Short CommunicationEndoscopic vocal fold injection using a 25-gauge butterfly needleM A Buchanana1 c1, F Riffata1 and C E Palmea1 a1 Department of Otolaryngology/Head and Neck Surgery, Westmead Hospital, Sydney, Australia Abstract Objective: To describe a useful technique for infiltrating a bulking agent using a butterfly needle, as part of a transoral endoscopic vocal fold medialisa...περισσότερα »

Endoscopic septoplasty

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
: Learning curve via European Annals of Otorhinolaryngology, Head and Neck Diseases Publication date: Available online 15 February 2016 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): C. Champagne, S. Ballivet de Régloix, L. Genestier, A. Crambert, O. Maurin, Y. Pons AimsThe aim of the current study was to report the learning curve for endoscopic septoplasty for a senior surgeon already trained in endonasal sinus surgery.Material and methodsFrom November 2011 to September 2012, 100 patients were prospectively included and grouped in 5 consecutive group... περισσότερα »

The diagnostic value of narrow band imaging in different oral and oropharyngeal subsites

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 40 δευτερόλεπτα
The diagnostic value of narrow band imaging in different oral and oropharyngeal subsites: AbstractThe diagnostic value of narrow band imaging (NBI) in the “optical biopsy” of leukoplakias (LP) and erythroplakias (EP) in different oral cavity (OC) and oropharyngeal (OP) subsites is still to be defined. We evaluated 128 unbiopsied and untreated OC/OP LP and EP by conventional oral examination (COE), white light (WL) endoscopy, and NBI and categorized them as “suspicious” or “innocuous”. All lesions were treated by excisional biopsy. True positives were those considered as “suspicious...περισσότερα »

Epidemiology of laryngeal carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 40 δευτερόλεπτα
in Germany, 1998–2011: AbstractConstituting 25–30 % of all head and neck cancer cases, laryngeal carcinoma is the most prevalent entity. Major risk factors of laryngeal cancer are smoking and excessive alcohol consumption. This study presents the recent developments in the incidence of laryngeal cancer from 1998 to 2011 in Germany. Laryngeal carcinoma was identified using International Statistical Classification of Diseases and Related Health Problems (ICD10) from German population-based cancer registries. The incidence was provided by the Robert Koch Institute, and the mortality ...περισσότερα »

The anterolateral thigh fold-over flap for total and subtotal glossectomy reconstruction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
The anterolateral thigh fold-over flap for total and subtotal glossectomy reconstruction: Background We present a fold-over technique for total and subtotal glossectomy reconstruction utilizing the ALT flap with the goal of increasing soft tissue bulk. Methods Retrospective review of total and subtotal glossectomy patients undergoing ALT fold-over flap reconstruction from January 2007 to December 2012. Results Eight patients fit inclusion criteria. Average length of follow-up was 35 months. There were no flap failures. At last follow-up, no patients were tracheostomy dependent. Six ... περισσότερα »

Cross-clamping of bony stumps in preparation for osteosynthesis in digital replantation

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 46 δευτερόλεπτα
from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1R60BtY via IFTTT

The anterolateral thigh fold-over flap for total and subtotal glossectomy reconstruction

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 46 δευτερόλεπτα
Background We present a fold-over technique for total and subtotal glossectomy reconstruction utilizing the ALT flap with the goal of increasing soft tissue bulk. Methods Retrospective review of total and subtotal glossectomy patients undergoing ALT fold-over flap reconstruction from January 2007 to December 2012. Results Eight patients fit inclusion criteria. Average length of follow-up was 35 months. There were no flap failures. At last follow-up, no patients were tracheostomy dependent. Six out of 8 patients (75%) did not require a g-tube and were able to maintain their weig... περισσότερα »

A little trick to make inside out vein graft technique easier in experimental animal models

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 46 δευτερόλεπτα
from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1R60BtU via IFTTT

The effects of surgical expansion of the maxillary arch and its consequences for the incisor axis

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 53 δευτερόλεπτα
Publication date: Available online 16 February 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): A. Moralis, K. Zitzmann, M. Gosau, D. Schlegel PurposeReduced transverse maxillary dental arch width may be treated either by surgically supported rapid maxillary expansion (SRME) with conservative orthodontic appliances or by means of Le Fort I osteotomy (LFIO). Both are means of transverse maxillary expansion.MethodsBoth surgical methods (SRME and LFIO) were evaluated with regard to the presurgical and postsurgical form of the maxillary dental arch and its consequences fo...περισσότερα »

Objective estimation of patient age through a new composite scale for facial aging assessment: The face - Objective assessment scale

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 53 δευτερόλεπτα
Publication date: Available online 15 February 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Simone La Padula, Barbara Hersant, Mounia SidAhmed, Jeremy Niddam, Jean Paul Meningaud Most patients requesting aesthetic rejuvenation treatment expect to look healthier and younger. Some scales for ageing assessment have been proposed, but none is focused on patient age prediction. The aim of this study was to develop and validate a new facial rating scale assessing facial ageing sign severity.One thousand Caucasian patients were included and assessed. The Rasch Model was... περισσότερα »

Diode endovascular laser treatment in venous malformations of the upper aerodigestive tract

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 53 δευτερόλεπτα
Publication date: Available online 15 February 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): François Simon, Nicolas Le Clerc, Didier Salvan, Elisabeth Sauvaget, Benoît Faucon, Michel Borsik, Philippe Herman, Annouk Bisdorff PurposeVenous malformations of the upper aerodigestive tract can cause pain, dysphagia, obstructive sleep apnea, and rarely bleeding. We studied 980-nm diode endovenous laser therapy.Material and MethodsThis is a 2007–2014 retrospective study in our vascular anomalies center. Data on patients' clinical history, polysomnography, magnetic resonan... περισσότερα »

Crescentic flap for the reconstruction of the nose after skin cancer resection

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 53 δευτερόλεπτα
Publication date: Available online 16 February 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Federica Arginelli, Attilio Carlo Salgarelli, Barbara Ferrari, Amanda Losi, Pierantonio Bellini, Cristina Magnoni PurposeNon-melanoma skin cancers are the most frequent skin tumours; in 25.5% of cases, they are reported to affect the nasal area. For an excellent surgical outcome, first of all the radical excision of the lesion is important, with appropriate margins of healthy skin in order to avoid recurrences. Moreover is important to achieve a good aesthetical result, av... περισσότερα »

Lateral Tarsotomy: A Practical Alternative to Lateral Canthotomy to Increase Orbital Access

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 54 δευτερόλεπτα
[image: alertIcon.gif] Publication date: Available online 16 February 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Hany A. Emam, Mark R. Stevens, Peter E. Larsen, Courtney A. Jatana ObjectiveTransconjunctival approach to the lower 1/3 of the orbit is commonly used to avoid transcutaneous incisions when surgical access is needed. A lateral canthotomy is used in conjunction with this approach if increased lateral exposure is required. A major disadvantage to the lateral canthotomy is difficulty in re-suspension of the lateral canthal tendon t...περισσότερα »

Patient outcomes following second surgery for recurrent glioblastoma

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 59 δευτερόλεπτα
Future Oncology Ahead of Print. from Cancer via ola Kala on Inoreader http://ift.tt/1U5m354 via IFTTT

Current topics in the multimodality treatment of locally advanced rectal cancer

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 59 δευτερόλεπτα
Future Oncology Ahead of Print. from Cancer via ola Kala on Inoreader http://ift.tt/1Wp8WKx via IFTTT

Role of palliative radiotherapy in the management of mural cardiac metastases: who, when and how to treat? A case series of 10 patients

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 59 δευτερόλεπτα
Abstract Cardiac metastases (CM), although a rare manifestation of metastatic cancer, are increasing in incidence with the improved prognosis and increased longevity of many patients with cancer. This condition may be life-threatening, especially for bulky rapidly growing tumors. Such cancer presentations may be amenable to palliative radiotherapy to improve symptoms and to prevent further cardiac function decline. Here, we report on our experience with 10 patients with mural CM who received radiotherapy (RT) to the heart with palliative intent. The radiation treatment was given i... περισσότερα »

Oral epithelial cells and their interactions with HIV-1

As the AIDS pandemic has continued, our understanding of the events that occur during the entry and infection of conventional, susceptible cells has increased dramatically, leading to the development of control therapies for HIV-infected individuals. However, an ongoing hole in our understanding is how HIV crosses the mucosal barriers to gain access to permissive cells, despite how important this information would be in developing successful vaccines and other preventative measures such as topical anti-HIV microbicides. In particular, our knowledge of the role that epithelial cel... περισσότερα »

The child and adolescent with HIV in resource poor countries

Although sub-Saharan Africa caries the burden of paediatric and adult HIV/AIDS infections, the epidemic is spreading most rapidly in the Middle East and North Africa Region where between 2005 and 2013, AIDS-related deaths increased by 66% in comparison with a worldwide fall of 35%. For the first time, in 2011, more than half of people in need of antiretroviral drugs were receiving them, with coverage reaching 54%; yet only 28% of children have access to HIV treatment. This review sought to provide an update of paediatric and adolescent oral HIV/AIDS issues in resource poor countr... περισσότερα »

The diagnostic value of narrow band imaging in different oral and oropharyngeal subsites

Abstract The diagnostic value of narrow band imaging (NBI) in the “optical biopsy” of leukoplakias (LP) and erythroplakias (EP) in different oral cavity (OC) and oropharyngeal (OP) subsites is still to be defined. We evaluated 128 unbiopsied and untreated OC/OP LP and EP by conventional oral examination (COE), white light (WL) endoscopy, and NBI and […]

Endoscopic septoplasty: Learning curve

Publication date: Available online 15 February 2016 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): C. Champagne, S. Ballivet de Régloix, L. Genestier, A. Crambert, O. Maurin, Y. Pons AimsThe aim of the current study was to report the learning curve for endoscopic septoplasty for a senior surgeon already trained in endonasal sinus surgery.Material […]

Global CD Copying Machine Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Global CD Copying Machine Industry 2016 and analysis by 2020 analyzed the world’s main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad in… from Infection via ola Kala on Inoreader http://ift.tt/1mELaOk via IFTTT from #Med […]

A rare location for fibrous dysplasia. The middle turbinate

Publication date: Available online 15 February 2016 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Sitki Gozeler, K. Kilic, M. Sedat Sakat, H. Ucuncu from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1om6nyo via IFTTT

Global Copying Apparatus Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Global Copying Apparatus Industry 2016 and analysis by 2020 analyzed the world’s main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad int… from Infection via ola Kala on Inoreader http://ift.tt/1Tnuucs via IFTTT from #Med Blogs […]

Global DE-Demi Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Global DE-Demi Industry 2016 and analysis by 2020 analyzed the world’s main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad introduction … from Infection via ola Kala on Inoreader http://ift.tt/1mELaxW via IFTTT from #Med Blogs […]

Congenital Hypothyroidism: Long-Term Experience with Early and High Levothyroxine Dosage

Aim: To assess the management and outcome of the congenital hypothyroidism (CH) patients followed at our institution since the introduction of systemic neonatal screening for CH. Study Design: The records of 139 CH patients referred to our center between 1978 and 2014 were retrospectively reviewed. Biochemical and imaging data at diagnosis, initial treatment and growth […]

Global Label printer Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Global Label printer Industry 2016 and analysis by 2020 analyzed the world’s main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad introdu… from Infection via ola Kala on Inoreader http://ift.tt/1TnutVY via IFTTT from #Med Blogs […]

Sexually Diergic Trophic Effects of Estradiol Exposure on Developing Bovine Cerebellar Granule Cells

In the mammalian brain, the differentiation of neural cells and the developmental organization of the underlying circuitry are influenced by steroid hormones. The estrogen 17-β estradiol is one of the most potent regulators of neural growth during prenatal life, synthetized locally from steroid precursors including prenatal testicular testosterone. Estradiol promotes brain differentiation counting sexually dimorphic […]

Ischemic postconditioning influences electron transport chain protein turnover in Langendorff-perfused rat hearts

Ischemia postconditioning (IPo) is a promising strategy in reducing myocardial ischemia reperfusion (I/R) injury (MIRI), but its specific molecular mechanism is incompletely understood. Langendorff-perfused isolated rat hearts were subjected to global I/R and received IPo in the absence or presence of the mitochondrial ATP-sensitive potassium channel (mitoKATP) blocker 5-hydroxydecanoate (5-HD). Myocardial mitochondria were extracted and […]

Social media helps Lake City police find drive-by suspect – ActionNewsJax.com

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
ActionNewsJax.com Social media helps Lake City police find drive-by suspect ActionNewsJax.com «It’s devastated my life,» said Kathleen Morgan, Rex Morgan’s widow. In 2010, doctors found a growth on Rex Morgan’s tonsil. It was cancer. Rigorous treatment began and he was told he was disease-free. In 2011, doctors found another lump – this time on …… Continue reading Social media helps Lake City police find drive-by suspect – ActionNewsJax.com

Endoscopic septoplasty: Learning curve

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 15 February 2016 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): C. Champagne, S. Ballivet de Régloix, L. Genestier, A. Crambert, O. Maurin, Y. Pons AimsThe aim of the current study was to report the learning curve for endoscopic septoplasty for a senior surgeon already trained in endonasal sinus surgery.Material… Continue reading Endoscopic septoplasty: Learning curve

A rare location for fibrous dysplasia. The middle turbinate

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 15 February 2016 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Sitki Gozeler, K. Kilic, M. Sedat Sakat, H. Ucuncu from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1om6nyo via IFTTT

Congenital Hypothyroidism: Long-Term Experience with Early and High Levothyroxine Dosage

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Aim: To assess the management and outcome of the congenital hypothyroidism (CH) patients followed at our institution since the introduction of systemic neonatal screening for CH. Study Design: The records of 139 CH patients referred to our center between 1978 and 2014 were retrospectively reviewed. Biochemical and imaging data at diagnosis, initial treatment and growth… Continue reading Congenital Hypothyroidism: Long-Term Experience with Early and High Levothyroxine Dosage

Computational studies of transport in ion channels using metadynamics

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 15 February 2016 Source:Biochimica et Biophysica Acta (BBA) – Biomembranes Author(s): Simone Furini, Carmen Domene Molecular dynamics simulations have played a fundamental role in numerous fields of science by providing insights into the structure and dynamics of complex systems at the atomistic level. However, exhaustive sampling by standard molecular dynamics is… Continue reading Computational studies of transport in ion channels using metadynamics

Long noncoding RNA ENST00000434223 suppressed tumor progression in non-small cell lung cancer

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Abstract In spite of the fact that the great progress has been made in the treatment of non-small cell lung cancer (NSCLC), the prognosis of NSCLC remains comparatively dismal. Therefore, it is of great value to identify novel effective diagnostic biomarkers and therapeutic targets of NSCLC. Emerging evidence has demonstrated the vital roles of long… Continue reading Long noncoding RNA ENST00000434223 suppressed tumor progression in non-small cell lung cancer

Linc-ROR induces epithelial-mesenchymal transition and contributes to drug resistance and invasion of breast cancer cells

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Abstract We aimed to investigate the role of large intergenic noncoding RNA regulator of reprogramming (linc-ROR) in the chemotherapy resistance of human breast cancer (BC) cells and its mechanism. A total of 142 patients diagnosed with BC in the First Affiliated Hospital, Zhejiang University between January 2012 and January 2014 were enrolled in our study.… Continue reading Linc-ROR induces epithelial-mesenchymal transition and contributes to drug resistance and invasion of breast cancer cells

Key Aspects of a Sustainable Health Insurance System in Germany

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Abstract Background The main goals of health-care systems are to improve the health of the population they serve, respond to people’s legitimate expectations, and offer fair financing. As a result, the health system in Germany is subject to continuous adaption as well as public and political discussions about its design. Objective This paper analyzes the… Continue reading Key Aspects of a Sustainable Health Insurance System in Germany

Sinusvenenthrombose: Hemikranektomie schlägt Rekanalisierung

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Druck reduzieren wichtiger Offenbar ist es bei einer schweren Sinusvenenthrombose wichtiger, den Druck aus dem Schädel zu nehmen, als das verstopfte Gefäß freizubekommen. Darauf deuten Ergebnisse einer deutschen Studie. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Xv1yyn via IFTTT

The role of prominence in determining the scope of boundary-related lengthening in Greek

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: March 2016 Source:Journal of Phonetics, Volume 55 Author(s): Argyro Katsika This study aims at examining and accounting for the scope of the temporal effect of phrase boundaries. Previous research has indicated that there is an interaction between boundary-related lengthening and prominence such that the former extends towards the nearby prominent syllable. However, it… Continue reading The role of prominence in determining the scope of boundary-related lengthening in Greek

The role of prominence in determining the scope of boundary-related lengthening in Greek

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: March 2016 *Source:*Journal of Phonetics, Volume 55 Author(s): Argyro Katsika This study aims at examining and accounting for the scope of the temporal effect of phrase boundaries. Previous research has indicated that there is an interaction between boundary-related lengthening and prominence such that the former extends towards the nearby prominent syllable. However, it is unclear whether this interaction is due to lexical stress and/or phrasal prominence (marked by pitch accent) and how far towards the prominent syllable the effect extends. Here, we use an electr...περισσότερα »

The relationship of pulmonary vascular resistance and compliance to pulmonary artery wedge pressure during submaximal exercise in healthy older adults

Abstract The resistive and pulsatile components of right ventricular afterload [pulmonary vascular resistance (Rp) and compliance (Cp)] are related by an inverse hyperbolic function, expressed as their product known as RpCp-time. The RpCp-time exhibits a narrow range, but may be altered by the pulmonary artery wedge pressure (PAWP). Elucidating the determinants of RpCp-time should improve the understanding of the physiologic behaviour of the pulmonary arterial systolic, diastolic, and mean pressure (PASP, PADP, mPAP) in response to perturbations. We examined the effect of exercise ...περισσότερα »

Carbon dioxide mediated vasomotion of extra-cranial cerebral arteries in humans: A role for prostaglandins?

Abstract Extra-cranial cerebral blood vessels are implicated in the regulation of cerebral blood flow during changes in arterial CO2; however, the mechanisms governing CO2 mediated vasomotion of these vessels in humans remain unclear. We determined if cyclooxygenase inhibition with Indomethacin (INDO) reduces the vasomotor response of the internal carotid artery (ICA) to changes in end-tidal CO2 (PETCO2). Using a randomized single-blinded placebo controlled study, participants (*n* = 10) were tested on two occasions, before and 90-minutes following oral INDO (1.2mg/kg) or placebo. ...περισσότερα »

The role of top-down spatial attention in contingent attentional capture

Abstract It is well known that attentional capture by an irrelevant salient item is contingent on top-down feature selection, but whether attentional capture may be modulated by top-down spatial attention remains unclear. Here, we combined behavioral and ERP measurements to investigate the contribution of top-down spatial attention to attentional capture under modified spatial cueing paradigms. Each target stimulus was preceded by a peripheral circular cue array containing a spatially uninformative color singleton cue. We varied target sets but kept the cue array unchanged among di... περισσότερα »

Model Studies towards Functionalized Bisbenzannulated [5,6]-Spiro­ketals

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Following up on our previous model studies on the synthesis of simple bisbenzannulated [5,6]-spiroketals we here report the preparation of new examples of this entity with a variation in their substitution pattern. The regioselective introduction of functional groups in the C-3 or C-3′ positions (rubromycin numbering) may either take place prior to the spiroketalization by α-functionalizations of the ketone moiety of the precursor or in a subsequent step by the nucleophilic substitution of the benzylic hydroxy group of the previously described C-3-hydroxylated spiroketal.... περισσότερα »

Experimental and Computational Study of Unique Tetranuclear µ3-Chloride and µ-Phenoxo/Chloro-Bridged Defective Dicubane Cobalt(II) Clusters

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Two tetranuclear CoII clusters [Co4(L)2(µ3-Cl)2Cl2] have been prepared by using multidentate diaminobisphenolate ligands. The solid-state structures of the complexes were determined by single-crystal X-ray diffraction. The cores of the cluster compounds can be defined as a two-vertex-deficient dicubane geometry (pseudo-dicubane). In the central unit, the cobalt(II) cations are linked through phenoxide oxygen (outer bridges) and chloride anions (inner bridges), previously unprecedented in this type of cobalt cluster. The magnetic properties were studied by both experimental... περισσότερα »

Global Personal 3D Printer Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Global Personal 3D Printer Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad i... from Infection via ola Kala on Inoreader http://ift.tt/1TnusBi via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PBSEMG via IFTTT

Global CD Copying Machine Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Global CD Copying Machine Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad in... from Infection via ola Kala on Inoreader http://ift.tt/1mELaOk via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PBSC7n via IFTTT

Global Copying Apparatus Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Global Copying Apparatus Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad int... from Infection via ola Kala on Inoreader http://ift.tt/1Tnuucs via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SuC2dk via IFTTT

Global DE-Demi Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Global DE-Demi Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad introduction ... from Infection via ola Kala on Inoreader http://ift.tt/1mELaxW via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PBSC7j via IFTTT

Global Label printer Market 2016 Size, Share, Trends, Analysis and Forecast to 2019

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Global Label printer Industry 2016 and analysis by 2020 analyzed the world's main region market size, share, trends, conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. The report begins with a broad introdu... from Infection via ola Kala on Inoreader http://ift.tt/1TnutVY via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SuBZyd via IFTTT

Ischemic postconditioning influences electron transport chain protein turnover in Langendorff-perfused rat hearts

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Ischemia postconditioning (IPo) is a promising strategy in reducing myocardial ischemia reperfusion (I/R) injury (MIRI), but its specific molecular mechanism is incompletely understood. Langendorff-perfused isolated rat hearts were subjected to global I/R and received IPo in the absence or presence of the mitochondrial ATP-sensitive potassium channel (mitoKATP) blocker 5-hydroxydecanoate (5-HD). Myocardial mitochondria were extracted and mitochondrial comparative proteomics was analyzed. IPo significantly reduces post-ischemic myocardial infarction and improved cardiac function in... περισσότερα »

A pan-cancer analysis of prognostic genes

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Numerous studies have identified prognostic genes in individual cancers, but a thorough pan-cancer analysis has not been performed. In addition, previous studies have mostly used microarray data instead of RNA-SEQ, and have not published comprehensive lists of associations with survival. Using recently available RNA-SEQ and clinical data from The Cancer Genome Atlas for 6,495 patients, we have investigated every annotated and expressed gene's association with survival across 16 cancer types. The most statistically significant harmful and protective genes were not shared across can...περισσότερα »

α-Phosphonovinyl Arylsulfonates: An Attractive Partner for the Synthesis of α-Substituted Vinylphosphonates through Palladium-Catalyzed Suzuki Reactions

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract It has been demonstrated that a variety of α-phosphonovinyl arylsulfonates with electron-neutral, -donating, and -withdrawing groups on the phenyl ring could be conveniently and efficiently prepared. In the presence of a Pd(OAc)2/SPhos-based catalyst, various organoboron compounds could be employed as the nucleophilic coupling partners, such as organoboronic acids, boronate esters, and organotrifluoroborates. The newly developed *O*-centered electrophiles could couple with a multitude of aryl, heteroaryl, and alkylboron reagents, to give α-substituted vinylphosphonates in ...περισσότερα »

Application of Deep Eutectic Solvents in Promiscuous Lipase-Catalysed Aldol Reactions

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract The application of deep eutectic solvents has been demonstrated for the first time in promiscuous lipase-catalysed aldol reactions. The model reaction between 4-nitrobenzaldehyde and acetone was examined in depth, with excellent compatibility being found between porcine pancreas lipase and choline chloride/glycerol mixtures for the formation of the aldol product in high yields. The system was compatible with a series of aromatic aldehydes and ketones including acetone, cyclopentanone and cyclohexanone. In some cases, the corresponding α,β-unsaturated carbonyl compounds wer...περισσότερα »

Model Studies towards Functionalized Bisbenzannulated [5,6]-Spiro­ketals

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Following up on our previous model studies on the synthesis of simple bisbenzannulated [5,6]-spiroketals we here report the preparation of new examples of this entity with a variation in their substitution pattern. The regioselective introduction of functional groups in the C-3 or C-3′ positions (rubromycin numbering) may either take place prior to the spiroketalization by α-functionalizations of the ketone moiety of the precursor or in a subsequent step by the nucleophilic substitution of the benzylic hydroxy group of the previously described C-3-hydroxylated spiroketal.... περισσότερα »

Experimental and Computational Study of Unique Tetranuclear µ3-Chloride and µ-Phenoxo/Chloro-Bridged Defective Dicubane Cobalt(II) Clusters

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Two tetranuclear CoII clusters [Co4(L)2(µ3-Cl)2Cl2] have been prepared by using multidentate diaminobisphenolate ligands. The solid-state structures of the complexes were determined by single-crystal X-ray diffraction. The cores of the cluster compounds can be defined as a two-vertex-deficient dicubane geometry (pseudo-dicubane). In the central unit, the cobalt(II) cations are linked through phenoxide oxygen (outer bridges) and chloride anions (inner bridges), previously unprecedented in this type of cobalt cluster. The magnetic properties were studied by both experimental... περισσότερα »

Diversity Oriented Synthesis of Allocolchicinoids with Fluoro and/or Oxygen Substituent(s) on the C-Ring from a Single Common Intermediate

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Allocolchicinoids, with a distinct polyoxygenated dibenzocycloheptane skeleton, attract much attention as potential candidate anticancer drugs. In this study, eight C-ring fluorinated analogues of allocolchicinoids, seven C-ring oxygen-substituted analogues, and known compounds *N*-acetylcolchinol and NSC 51046 were synthesized as racemates from a single common intermediate by using either the deoxyfluorination/migration domino reaction or acid-promoted migration as the key step. Among the products obtained, some of the fluorinated derivatives strongly inhibited the growth...περισσότερα »

Computed tomography in trauma patients using iterative reconstruction: reducing radiation exposure without loss of image quality

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Background Rising numbers of computed tomography (CT) examinations worldwide have led to a focus on dose reduction in the latest developments in CT technology. Iterative reconstruction (IR) models bear the potential to effectively reduce dose while maintaining adequate image quality. Purpose To assess the impact of adaptive statistical iterative reconstruction (ASIR) technique on dose reduction and image quality in a dedicated whole body CT (WBCT) protocol for trauma patients. Material and Methods A total of 122 subjects with multiple trauma was prospectively included in our st... περισσότερα »

A comparison of liver fat content as determined by magnetic resonance imaging-proton density fat fraction and MRS versus liver histology in non-alcoholic fatty liver disease

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Background Many imaging methods have been defined for quantification of hepatic steatosis in non-alcoholic fatty liver disease (NAFLD). However, studies comparing the efficiency of magnetic resonance imaging-proton density fat fraction (MRI-PDFF), magnetic resonance spectroscopy (MRS), and liver histology for quantification of liver fat content are limited. Purpose To compare the efficiency of MRI-PDFF and MRS in the quantification of liver fat content in individuals with NAFLD. Material and Methods A total of 19 NAFLD patients underwent MRI-PDFF, MRS, and liver biopsy for quan... περισσότερα »

Uterine cervical cancer volumetry using T2- and diffusion-weighted MR images in patients treated by primary surgery and neoadjuvant chemotherapy

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Background Tumor volumetry with magnetic resonance imaging (MRI) is very common; however, the accuracy of such measures remains unclear, especially after treatment. Purpose To determine the accuracy of preoperative volume measurements of uterine cervical carcinomas resected with and without neoadjuvant chemotherapy (NAC) on T2-weighted (T2W) and diffusion-weighted (DWI) MRI. Material and Methods Twenty-nine consecutive patients with surgically confirmed uterine cervical carcinoma were included in this study. MRI scans were performed before preoperative treatment in 17 patients ... περισσότερα »

80-kVp CT angiography for endovascular aneurysm repair follow-up with halved contrast medium dose and preserved diagnostic quality

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Background Follow-up of endovascular aneurysm repair (EVAR) with life-long computed tomography angiography (CTA) surveillance exposes patients with impaired renal function to repeated risks of contrast medium-induced nephropathy (CIN). Purpose To retrospectively compare vascular attenuation, image noise, contrast-to-noise ratio (CNR), subjective image quality and effective radiation dose (mSv) for CTA with a 16-multirow detector CT (MDCT) equipment at 80 kVp after EVAR using a contrast medium (CM) dose that is half of that used at 120 kVp. Material and Methods Forty patients w...περισσότερα »

Genes, Vol. 7, Pages 9: Impact of DCC (rs714) and PSCA (rs2294008 and rs2976392) Gene Polymorphism in Modulating Cancer Risk in Asian Population

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Multiple studies have investigated the association of gene variant of Deleted in colorectal carcinoma (DCC) and Prostate Stem cell antigen (PSCA) with various cancer susceptibility; however, the results are discrepant. Since SNPs are emerging as promising biomarker of cancer susceptibility, here, we aimed to execute a meta-analysis of DCC (rs714 A &gt; G) and PSCA (rs2294008 C &gt; T, rs2976392 G &gt; A) polymorphism to demonstrate the more accurate strength of these associations. We followed a rigorous inclusion/exclusion criteria and calculated the pooled odds ratios (ORs) and 95% confid... περισσότερα »

Plant Antimicrobials and the Food Industry: Part 4 – Application and Regulation

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: garlic_oil__isolated_on_a_white_backgrou] Antimicrobials derived from plants represent an exciting new direction in food safety and product management for the food industry1. Since consumer preference is for natural products with limited perceived chemical adulteration, replacing traditional food additives with effective plant antimicrobials could win acceptance from buyers. Applications There are three main areas in which plant antimicrobials are Read the rest of this article The post Plant Antimicrobials and the Food Industry: Part 4 – Application and Regulation appeare... περισσότερα »

Plant Antimicrobials and the Food Industry: Part 4 – Application and Regulation

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: garlic_oil__isolated_on_a_white_backgrou] Antimicrobials derived from plants represent an exciting new direction in food safety and product management for the food industry1. Since consumer preference is for natural products with limited perceived chemical adulteration, replacing traditional food additives with effective plant antimicrobials could win acceptance from buyers. Applications There are three main areas in which plant antimicrobials are Read the rest of this article The post Plant Antimicrobials and the Food Industry: Part 4 – Application and Regulation appeare... περισσότερα »

Charge-Transfer Salts Based on a Dissymmetrical Cyano-Substituted Tetrathiafulvalene Donor

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
Abstract Three salts of the dissymmetrical TTF derivative cyanobenzene-ethylenedithio-tetrathiafulvalene (CNB-EDT-TTF) with different anions, namely, (CNB-EDT-TTF)2[M(mnt)2] [M = Ni (*1*), Au (*2*); mnt = maleonitriledithiolate] and (CNB-EDT-TTF)FeBr4 (*3*) were prepared and characterized by single-crystal X-ray diffraction, magnetic susceptibility, and electrical conductivity measurements. Compounds *1* and *2* are isostructural with a crystal structure characterized by segregated chains of side-by-side donor dimers and acceptors, and compound *3* presents donors in dimerized sta... περισσότερα »

Synthesis of a Family of ([SnSe]1+δ)m­([{MoxNb1x}Se2]1+γ)1([SnSe]1+δ)m­({Nbx­Mo1–x}Se2)1 Superlattice ­Heterostructures (m = 0, 1, 2, 3, 4 ­and 0.8 ≤ x ≤ 1)

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
Abstract A family of multiple-component heterostructures, ([SnSe]1+*δ*)*m*([{Mo*x*Nb 1–*x*}Se2]1+*γ*)1([SnSe]1+*δ*)*m*({Nb*x*Mo1–*x*}Se2)1 (*m* = 0, 1, 2, 3, 4 and 0.8 ≤ *x* ≤ 1), was self-assembled from designed amorphous precursors, and their structure and physical properties were characterized. The compounds consist of MoSe2 and NbSe2 layers with metal centers in a trigonal-prismatic environment interleaved with systematically increasing numbers of SnSe bilayers with a distorted rock salt structure. The extent of alloying of the miscible dichalcogenide constituents decreased from...περισσότερα »

‘Classic papers in this issue of Acta Radiologica

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1VjeRAx via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SuAfF7 via IFTTT

PPIP5K1 interacts with the exocyst complex through a C-terminal intrinsically disordered domain and regulates cell motility

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: May 2016 *Source:*Cellular Signalling, Volume 28, Issue 5 Author(s): Gayane Machkalyan, Phan Trieu, Darlaine Pétrin, Terence E. Hébert, Gregory J. Miller Cellular signaling involves coordinated regulation of many events. Scaffolding proteins are crucial regulators of cellular signaling, because they are able to affect numerous events by coordinating specific interactions among multiple protein partners in the same pathway. Scaffolding proteins often contain intrinsically disordered regions (IDR) that facilitate the formation and function of distinct protein complex... περισσότερα »

Prediction of hard meningiomas: quantitative evaluation based on the magnetic resonance signal intensity

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Background From a surgical perspective, presurgical prediction of meningioma consistency is beneficial. Purpose To quantitatively analyze the correlation between the magnetic resonance (MR) signal intensity (SI) or apparent diffusion coefficient (ADC) and meningioma consistency and to determine which MR sequence could help predicting hard meningiomas. Material and Methods This study included 43 patients with meningiomas who underwent preoperative MR imaging (MRI), including T1-weighted (T1W) imaging, T2-weighted (T2W) imaging, fluid-attenuated inversion recovery (FLAIR), diffus... περισσότερα »

Two-dimensional ultra-thin SiOx (0 &lt; x &lt; 2) nanosheets with long-term cycling stability as lithium ion battery anodes

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC00723F, Communication Lin Sun, Tingting Su, Lei Xu, Meipin Liu, Hongbin Du Ultra-thin SiOx (0 &lt; x &lt; 2) nanosheets were obtained via a convenient solvothermal route from Zintl compound CaSi2. After carbon coating, the SiOx@C nanosheet anodes exhibit high capacity, good... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1Vjh3rR via IFTTT

DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC01238H, Communication Chia-Chen Chang, Chie-Pein Chen, Chen-Yu Chen, Chii-Wann Lin A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1RIT4n4 via IFTTT

Bifunctional Tertiary Amine-Squaramide Catalyzed Asymmetric Catalytic 1,6-Conjugate Addition/Aromatization of para-Quinone Methides with Oxindoles

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C5CC10502A, Communication Yu-Hua Deng, Xiang-Zhi Zhang, Ke-Yin Yu, Xu Yan, Ji-Yuan Du, Hanmin Huang, Chun-An Fan Asymmetric catalytic 1,6-addition of *p*-QMs with racemic oxindoles under the bifunctional catalysis of *C*2-symmetric dimeric *Cinchona*-derived squaramides is described. This tertiary amine-squaramide catalzyed reaction provides a diastereoselective and enantioselective approach... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader... περισσότερα »

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