Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τρίτη 9 Φεβρουαρίου 2016

OtoRhinoLaryngology & Medicine,New Articles,February 9th,2016,a


Evidence for involvement of NK3 receptors in the anxiogenic-like effect of SP6-11(C-terminal), a metabolite of substance P, in rats evaluated in the elevated plus-maze

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 λεπτό
[image: S01664328.gif] Publication date: 15 April 2016 *Source:*Behavioural Brain Research, Volume 303 Author(s): Filipe Silveira Duarte, Marcelo Duzzioni, Leandro Rinaldi Leme, Saulo de Paiva Smith, Thereza C.M. De Lima IntroductionSubstance P (SP) is a neuropeptide widely expressed throughout the fear-processing pathways of the brain. SP is cleaved by several proteolytic enzymes in amino (N-) and carboxy (C-) terminal sequences, which can have biological activities per se. We have previously shown that the anxiogenic-like effects elicited by SP6-11(C-terminal), a specific metaboli... περισσότερα »

Learning, memory and long-term potentiation are altered in Nedd4 heterozygous mice

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 λεπτό
[image: alertIcon.gif] Publication date: 15 April 2016 *Source:*Behavioural Brain Research, Volume 303 Author(s): Daria Camera, Harold A. Coleman, Helena C. Parkington, Trisha A. Jenkins, David V. Pow, Natasha Boase, Sharad Kumar, Philip Poronnik The consolidation of short-term memory into long-term memory involves changing protein level and activity for the synaptic plasticity required for long-term potentiation (LTP). AMPA receptor trafficking is a key determinant of LTP and recently ubiquitination by Nedd4 has been shown to play an important role via direct action on the GluA1 sub... περισσότερα »

Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
*Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.* Int J Audiol. 2016 Feb 6;:1-6 Authors: English R, Plant K, Maciejczyk M, Cowan R Abstract OBJECTIVE: For a group of cochlear implant recipients, who use hearing aids in the contralateral ear, the benefit of NAL-NL2 relative to a recipients' own prescription was assessed. Whether there was a preferred frequency response and/or gain deviation from NAL-NL2 was then investigated. DESIGN: Speech recognition and self-reported ratings of benefi...περισσότερα »

Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
*Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.* Int J Audiol. 2016 Feb 6;:1-6 Authors: English R, Plant K, Maciejczyk M, Cowan R Abstract OBJECTIVE: For a group of cochlear implant recipients, who use hearing aids in the contralateral ear, the benefit of NAL-NL2 relative to a recipients' own prescription was assessed. Whether there was a preferred frequency response and/or gain deviation from NAL-NL2 was then investigated. DESIGN: Speech recognition and self-reported ratings of benefi...περισσότερα »

Normative data on audiovisual speech integration using sentence recognition and capacity measures.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
*Normative data on audiovisual speech integration using sentence recognition and capacity measures.* Int J Audiol. 2016 Feb 6;:1-9 Authors: Altieri N, Hudock D Abstract OBJECTIVE: The ability to use visual speech cues and integrate them with auditory information is important, especially in noisy environments and for hearing-impaired (HI) listeners. Providing data on measures of integration skills that encompass accuracy and processing speed will benefit researchers and clinicians. DESIGN: The study consisted of two experiments: First, accuracy scores were obtained using City Univ... περισσότερα »

Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
*Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.* Int J Audiol. 2016 Feb 6;:1-6 Authors: English R, Plant K, Maciejczyk M, Cowan R Abstract OBJECTIVE: For a group of cochlear implant recipients, who use hearing aids in the contralateral ear, the benefit of NAL-NL2 relative to a recipients' own prescription was assessed. Whether there was a preferred frequency response and/or gain deviation from NAL-NL2 was then investigated. DESIGN: Speech recognition and self-reported ratings of benefi...περισσότερα »

Normative data on audiovisual speech integration using sentence recognition and capacity measures.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
*Normative data on audiovisual speech integration using sentence recognition and capacity measures.* Int J Audiol. 2016 Feb 6;:1-9 Authors: Altieri N, Hudock D Abstract OBJECTIVE: The ability to use visual speech cues and integrate them with auditory information is important, especially in noisy environments and for hearing-impaired (HI) listeners. Providing data on measures of integration skills that encompass accuracy and processing speed will benefit researchers and clinicians. DESIGN: The study consisted of two experiments: First, accuracy scores were obtained using City Univ... περισσότερα »

Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
*Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.* Int J Audiol. 2016 Feb 6;:1-6 Authors: English R, Plant K, Maciejczyk M, Cowan R Abstract OBJECTIVE: For a group of cochlear implant recipients, who use hearing aids in the contralateral ear, the benefit of NAL-NL2 relative to a recipients' own prescription was assessed. Whether there was a preferred frequency response and/or gain deviation from NAL-NL2 was then investigated. DESIGN: Speech recognition and self-reported ratings of benefi...περισσότερα »

Normative data on audiovisual speech integration using sentence recognition and capacity measures.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
*Normative data on audiovisual speech integration using sentence recognition and capacity measures.* Int J Audiol. 2016 Feb 6;:1-9 Authors: Altieri N, Hudock D Abstract OBJECTIVE: The ability to use visual speech cues and integrate them with auditory information is important, especially in noisy environments and for hearing-impaired (HI) listeners. Providing data on measures of integration skills that encompass accuracy and processing speed will benefit researchers and clinicians. DESIGN: The study consisted of two experiments: First, accuracy scores were obtained using City Univ... περισσότερα »

Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
*Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.* Int J Audiol. 2016 Feb 6;:1-6 Authors: English R, Plant K, Maciejczyk M, Cowan R Abstract OBJECTIVE: For a group of cochlear implant recipients, who use hearing aids in the contralateral ear, the benefit of NAL-NL2 relative to a recipients' own prescription was assessed. Whether there was a preferred frequency response and/or gain deviation from NAL-NL2 was then investigated. DESIGN: Speech recognition and self-reported ratings of benefi...περισσότερα »

Normative data on audiovisual speech integration using sentence recognition and capacity measures.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
*Normative data on audiovisual speech integration using sentence recognition and capacity measures.* Int J Audiol. 2016 Feb 6;:1-9 Authors: Altieri N, Hudock D Abstract OBJECTIVE: The ability to use visual speech cues and integrate them with auditory information is important, especially in noisy environments and for hearing-impaired (HI) listeners. Providing data on measures of integration skills that encompass accuracy and processing speed will benefit researchers and clinicians. DESIGN: The study consisted of two experiments: First, accuracy scores were obtained using City Univ... περισσότερα »

Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
*Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.* Int J Audiol. 2016 Feb 6;:1-6 Authors: English R, Plant K, Maciejczyk M, Cowan R Abstract OBJECTIVE: For a group of cochlear implant recipients, who use hearing aids in the contralateral ear, the benefit of NAL-NL2 relative to a recipients' own prescription was assessed. Whether there was a preferred frequency response and/or gain deviation from NAL-NL2 was then investigated. DESIGN: Speech recognition and self-reported ratings of benefi...περισσότερα »

Pubblicate le «Raccomandazioni per il corretto supporto nutrizionale del paziente oncologico»

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 δευτερόλεπτα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/20T4OFN via IFTTT

Review of Heil, John Paul. Hebrews: chiastic structures and audience response. Publisher: Washington, DC: Catholic Biblical Assoc. of America, 2010

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 δευτερόλεπτα
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Rezension von: Calaway, Jared C.: The Sabbath and the Sanctuary. Access to God in the Letter to the Hebrews and its Priestly Context, Tübingen 2013

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 δευτερόλεπτα
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Traditional uses, phytochemistry and pharmacological properties of Neolamarckia cadamba: A review

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 δευτερόλεπτα
Publication date: 2 April 2016 Source:Journal of Ethnopharmacology, Volume 181 Author(s): Arti Pandey, Pradeep Singh Negi Ethnopharmacological relevanceThere are more than 3000 officially documented plants in the Indian subcontinent that hold great medicinal potential. One such under-explored plant is an evergreen tropical tree Neolamarckia cadamba (Roxb.) Bosser (Rubiaceae). It is widely distributed in tropical and… Continue reading Traditional uses, phytochemistry and pharmacological properties of Neolamarckia cadamba: A review

Dr Van Vuurden of @VUmcAmsterdam discusses convection-enhanced delivery of drugs to brain tumours in children https://t.co/CdmmCCsGF6

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 δευτερόλεπτα
Dr Van Vuurden of @VUmcAmsterdam discusses convection-enhanced delivery of drugs to brain tumours in children https://t.co/CdmmCCsGF6 from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/697047337143820289 via IFTTT

Anti-diabetic effect of Xylopia aethiopica (Dunal) A. Rich. (Annonaceae) fruit acetone fraction in a type 2 diabetes model of rats

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 δευτερόλεπτα
Publication date: 2 March 2016 Source:Journal of Ethnopharmacology, Volume 180 Author(s): Aminu Mohammed, Neil Anthony Koorbanally, Md. Shahidul Islam Ethnopharmacological relevanceIn traditional medicine from West Africa, the fruit decoction of Xylopia aethiopica (Dunal) A. Rich. is widely used for the treatment of diabetes mellitus (DM) either alone or in combination with other plants. The present… Continue reading Anti-diabetic effect of Xylopia aethiopica (Dunal) A. Rich. (Annonaceae) fruit acetone fraction in a type 2 diabetes model of rats

Device hits pancreatic tumours hard with toxic 4-drug cocktail, sparing the body https://t.co/nitPg8Wa2G

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 δευτερόλεπτα
Device hits pancreatic tumours hard with toxic 4-drug cocktail, sparing the body https://t.co/nitPg8Wa2G from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/697032236055396352 via IFTTT

Review of Heil, John Paul. Hebrews: chiastic structures and audience response. Publisher: Washington, DC: Catholic Biblical Assoc. of America, 2010

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I am Innately Aggressive, Not Innately Warlike

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 δευτερόλεπτα
War and hockey, although they tap into innate human aggression, are both learned, culturally-driven behaviors.

World War II Vet Has Mustard Gas Exposure Claims Denied by VA – Military.com

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 δευτερόλεπτα
Military.com World War II Vet Has Mustard Gas Exposure Claims Denied by VA Military.com Harrell, known as «Arlie,» has been rejected three times by the Department of Veterans Affairs for claims to help treat a lung disorder and skin cancer that his family believes are connected to that exposure. Harrell, who turns 89 next month,… Continue reading World War II Vet Has Mustard Gas Exposure Claims Denied by VA – Military.com

Clear Cell Atypical Fibroxanthoma,Clear cell melanoma, primary cutaneous and metastatic clear cell carcinomas, clear cell sarcoma, pleomorphic liposarcoma, tumor of perivascular epithelioid cells, and distinctive dermal clear cell mesenchymal neoplasm

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Clear Cell Atypical Fibroxanthoma: Clinicopathological Study of 6 Cases and Review of the Literature With Special Emphasis on the Differential Diagnosis.: *Clear Cell Atypical Fibroxanthoma: Clinicopathological Study of 6 Cases and Review of the Literature With Special Emphasis on the Differential Diagnosis.* Am J Dermatopathol. 2016 Feb 4; Authors: Tardío JC, Pinedo F, Aramburu JA, Martínez-González MÁ, Arias D, Khedaoui R, Suárez-Massa D, Santonja C Abstract Atypical fibroxanthoma (AFX) is an uncommon dermal-based neoplasm arising on the sun-damaged skin of elderly people. Cle... περισσότερα »

Acute lymphoblastic leukemia, colorectal cancer, breast cancer, melanoma, and sarcoma.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Biologic and clinical characteristics of adolescent and young adult cancers: Acute lymphoblastic leukemia, colorectal cancer, breast cancer, melanoma, and sarcoma Cancer. 2016 Feb 5; Authors: Tricoli JV, Blair DG, Anders CK, Bleyer A, Boardman LA, Khan J, Kummar S, Hayes-Lattin B, Hunger SP, Merchant M, Seibel NL, Thurin M, Willman CL Abstract Adolescent and young adult (AYA) patients with cancer have not attained the same improvements in overall survival as either younger children or older adults. One possible reason for this disparity may be that the AYA cancers exhibit unique ...περισσότερα »

The melanoma-specific graded prognostic assessment does not adequately discriminate prognosis in a modern population with brain metastases from malignant melanoma.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
[image: http:--www.nature.com-images-lo_bjc.gif] Authors: Wilkins A, Furness A, Corbett RW, Bloomfield A, Porta N, Morris S, Ali Z, Larkin J, Harrington K Abstract BACKGROUND: The melanoma-specific graded prognostic assessment (msGPA) assigns patients with brain metastases from malignant melanoma to 1 of 4 prognostic groups. It was largely derived using clinical data from patients treated in the era that preceded the development of newer therapies such as BRAF, MEK and immune checkpoint inhibitors. Therefore, its current relevance to patients diagnosed with brain metastases from m... περισσότερα »

Basal cell carcinoma, squamous cell carcinoma and melanoma of the head and face

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Basal cell carcinoma, squamous cell carcinoma and melanoma of the head and face: AbstractUltraviolet light (UV) is an important risk factor for cutaneous basal cell carcinoma, cutaneous squamous cell carcinoma and cutaneous melanoma of the skin. These cancers most commonly affect persons with fair skin and blue eyes who sunburn rather than suntan. However, each of these cancers appears to be associated with a different pattern of UV exposure and to be mediated by different intracellular molecular pathways. Some melanocortin 1 receptor (MC1R) gene variants play a direct role in the ...περισσότερα »

Therapeutic advances for the tumors associated with neurofibromatosis type 1, type 2, and schwannomatosis

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Therapeutic advances for the tumors associated with neurofibromatosis type 1, type 2, and schwannomatosis: Neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis (SWN) are tumor-suppressor syndromes. Each syndrome is an orphan disease; however, the tumors that arise within them represent the most common tumors of the nervous system worldwide. Systematic investigation of the pathways impacted by the loss of function of neurofibromin (encoded by *NF1*) and merlin (encoded by *NF2*) have led to therapeutic advances for patients with NF1 and NF2. In the syn... περισσότερα »

Therapeutic advances for the tumors associated with neurofibromatosis type 1, type 2, and schwannomatosis.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Therapeutic advances for the tumors associated with neurofibromatosis type 1, type 2, and schwannomatosis.: Neuro Oncol. 2016 Feb 6; Authors: Blakeley JO, Plotkin SR Abstract Neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis (SWN) are tumor-suppressor syndromes. Each syndrome is an orphan disease; however, the tumors that arise within them represent the most common tumors of the nervous system worldwide. Systematic investigation of the pathways impacted by the loss of function of neurofibromin (encoded by NF1) and merlin (encoded by NF2) have led... περισσότερα »

Using frozen section margin control technique to manage non-melanomatous skin lesions in high-risk sites.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Using frozen section margin control technique to manage non-melanomatous skin lesions in high-risk sites.: Authors: Nizamoglu M, Douglas H, McArdle C, Mathew B, Vize C, Matteucci P Abstract BACKGROUND: In the UK, non-melanoma skin cancers (NMSCs) that are incompletely excised, recurrent or in sites high risk for incomplete excision are often offered Mohs micrographic surgery (MMS). Variations in waiting times and geographical access to MMS affect patient preference for other treatments. Our unit offers excision of such lesions under complete margin frozen section histological exami...περισσότερα »

Impact on overall survival of the combination of BRAF inhibitors and stereotactic radiosurgery in patients with melanoma brain metastases

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Impact on overall survival of the combination of BRAF inhibitors and stereotactic radiosurgery in patients with melanoma brain metastases: AbstractThe aim of this study was to evaluate the impact of BRAF inhibitors on survival outcomes in patients receiving stereotactic radiosurgery (SRS) for melanoma brain metastases. We prospectively collected treatment parameters and outcomes for 80 patients with melanoma brain metastases who underwent SRS. Thirty-five patients harbored the *BRAF* mutation (BRAF-M) and 45 patients did not (BRAF-WT). Univariate and multivariate analyses were perf... περισσότερα »

Dissecting Therapeutic Resistance to ERK Inhibition

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Dissecting Therapeutic Resistance to ERK Inhibition: The MAPK pathway is frequently activated in many human cancers, particularly melanomas. A single nucleotide mutation in BRAF resulting in the substitution of glutamic acid for valine (V600E) causes constitutive activation of the downstream MAPK pathway. Selective BRAF and MEK inhibitor therapies have demonstrated remarkable anti-tumor responses in BRAFV600E mutant melanoma patients. However, initial tumor shrinkage is transient and the vast majority of patients develop resistance. We previously reported that SCH772984, an ERK 1/2... περισσότερα »

Enhancing the tumor selectivity of a picornavirus virotherapy promotes tumor regression and the accumulation of infiltrating CD8+ T-cells

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Enhancing the tumor selectivity of a picornavirus virotherapy promotes tumor regression and the accumulation of infiltrating CD8+ T-cells: Picornaviruses have emerged as promising cancer therapies due to their ability to drive cytotoxic cellular immune responses and for promoting oncolysis. These properties include preferential replication in tumor cells, the induction of strong innate and adaptive immune responses and the ease with which their genomes can be manipulated. We have developed Theiler's murine encephalomyelitis virus (TMEV) as an immunotherapy vector that promotes stro... περισσότερα »

Malignant melanoma arising in melanin-producing medullary thyroid carcinoma.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Malignant melanoma arising in melanin-producing medullary thyroid carcinoma. : Authors: Hirokawa M, Miyauchi A, Otsuru M, Daa T Abstract INTRODUCTION: We report a case of malignant melanoma arising in medullary thyroid carcinoma that has not yet been described. PRESENTATION OF CASE: A 66-year-old woman presented with a mass in her thyroid. The resected mass was black in color, and was composed of a mixture of classic medullary thyroid carcinoma and pleomorphic atypical cells containing melanin pigments. The pleomorphic atypical cells were morphologically consistent with malignant m... περισσότερα »

A novel ATM-dependent checkpoint defect distinct from loss of function mutation promotes genomic instability in melanoma

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
A novel ATM-dependent checkpoint defect distinct from loss of function mutation promotes genomic instability in melanoma: [image: cover.gif?v=1&s=f3d98c753a39c60ab03ce3a3] Abstract Melanomas have high levels of genomic instability that can contribute to poor disease prognosis. Here, we report a novel defect of the ATM-dependent cell cycle checkpoint in melanoma cell lines that promotes genomic instability. In defective cells, ATM signalling to CHK2 is intact, but the cells are unable to maintain the cell cycle arrest due to elevated PLK1 driving recovery from the arrest. Reducin... περισσότερα »

Treatment of elderly patients with melanoma

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Treatment of elderly patients with melanoma: AbstractTreatment options for melanoma patients, both young and old, were extremely limited until recently. Elderly patients faced a particular challenge due to less aggressive surgical management, poor tolerance of available therapies, aggressive biologic behaviors, and rapid tumor progression. Over the past several years, however, a number of remarkably active immune and targeted agents have been developed. These agents are generally well tolerated and present numerous effective therapeutic options for elderly patients with advanced me...περισσότερα »

Localization of the Sentinel Lymph Node in Melanoma Without Blue Dye

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Localization of the Sentinel Lymph Node in Melanoma Without Blue Dye: [image: image] Objective: The purpose of this study was to assess regional recurrence rates of patients who underwent sentinel lymph node biopsy (SLNB) using radiocolloid guidance alone. Background: Isosulfan blue dye is commonly used along with Tc99-labeled radiocolloid localization in SLNB for melanoma. Blue dye has, however, been associated with allergic reactions, long-term staining of skin, and increased cost. We hypothesized that the rate of regional recurrence when SLNB is performed with radiocolloid alone ... περισσότερα »

Association of Interferon Regulatory Factor-4 Polymorphism rs12203592 With Divergent Melanoma Pathways

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Association of Interferon Regulatory Factor-4 Polymorphism rs12203592 With Divergent Melanoma Pathways: Background: Solar elastosis and neval remnants are histologic markers characteristic of divergent melanoma pathways linked to differences in age at onset, host phenotype, and sun exposure. However, the association between these pathway markers and newly identified low-penetrance melanoma susceptibility loci remains unknown. Methods: In the Genes, Environment and Melanoma (GEM) Study, 2103 Caucasian participants had first primary melanomas that underwent centralized pathology rev... περισσότερα »

Final Results of the Sunbelt Melanoma Trial: A Multi-Institutional Prospective Randomized Phase III Study Evaluating the Role of Adjuvant High-Dose Interferon Alfa-2b and Completion Lymph Node Dissection for Patients Staged by Sentinel Lymph Node Biopsy [Melanoma]

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Final Results of the Sunbelt Melanoma Trial: A Multi-Institutional Prospective Randomized Phase III Study Evaluating the Role of Adjuvant High-Dose Interferon Alfa-2b and Completion Lymph Node Dissection for Patients Staged by Sentinel Lymph Node Biopsy [Melanoma]: Purpose The Sunbelt Melanoma Trial is a prospective randomized trial evaluating the role of high-dose interferon alfa-2b therapy (HDI) or completion lymph node dissection (CLND) for patients with melanoma staged by sentinel lymph node (SLN) biopsy. Patients and Methods Patients were eligible if they were age 18 to 70 yea...περισσότερα »

CD10, B-cell lymphoma 6 protein (Bcl-6), mutated melanoma-associated antigen 1 (MUM1), germinal center B-cell-expressed transcript 1 (GCET1), forkhead box protein P1 (FOXP1), and LIM do-main only 2 (LMO2)

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
[image: http:--www.funpecrp.com.br-gmr-images-bt] Authors: Li JM, Hou J, Li L, Wang Y Abstract The objectives of this study were to detect immunohistochemical subtypes of diffuse large B-cell lymphoma (DLBCL) of the head and neck, to compare the Hans, Choi, and Tally algorithms and to examine the significance of protein expression in these algorithms. This study included 103 DLBCL patients at Sichuan Cancer Hospital between May 2010 and October 2012. Immunohistochemistry was per-formed for CD10, B-cell lymphoma 6 protein (Bcl-6), mutated melanoma-associated antigen 1 (MUM1), germ... περισσότερα »

Chemotherapy for advanced non-pancreatic well-differentiated neuroendocrine tumours of the gastrointestinal tract, a systematic review and meta-analysis: A lost cause?

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
*Chemotherapy for advanced non-pancreatic well-differentiated neuroendocrine tumours of the gastrointestinal tract, a systematic review and meta-analysis: A lost cause?* Cancer Treat Rev. 2016 Jan 25;44:26-41 Authors: Lamarca A, Elliott E, Barriuso J, Backen A, McNamara MG, Hubner R, Valle JW Abstract BACKGROUND: Chemotherapy is well-established in the treatment of patients with well-differentiated neuroendocrine tumours (NETs) arising from the pancreas (pNETs); however, its role in patients with gastrointestinal non-pancreatic NETs (non-pNETs) is uncertain. This systematic revie...περισσότερα »

[Characterization of the Laryngeal Adductor Reflex by Stimulation with Microdroplets Impulses (Microdroplet Impulse Testing)].

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
*[Characterization of the Laryngeal Adductor Reflex by Stimulation with Microdroplets Impulses (Microdroplet Impulse Testing)].* Laryngorhinootologie. 2016 Feb 8; Authors: Ptok M, Schroeter S Abstract Background: The larynx is considered a crossing point between breathing and swallowing pathways. During swallowing, the airway below the glottis must be protected against food components by an appropriate laryngeal closure mechanism. The laryngeal adductor reflex (LAR) with an early, probably di- or oligosynaptic interconnected ipsilateral LAR1- and a late ipsilateral and contralate...περισσότερα »

Neoadjuvant chemotherapy in technically unresectable carcinoma of external auditory canal.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
*Neoadjuvant chemotherapy in technically unresectable carcinoma of external auditory canal.* Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):172-175 Authors: Joshi A, Tandon N, Noronha V, Dhumal S, Patil V, Arya S, Juvekar S, Agarwal J, DCruz A, Pai P, Prabhash K Abstract BACKGROUND: Carcinoma of external auditory canal (EAC) is a very rare malignancy with surgical resection as the main modality of treatment. The outcomes with nonsurgical modalities are very dismal. We present a retrospective analysis of 4 patients evaluating the role of neoadjuvant chemotherapy in technically un... περισσότερα »

Pediatric Differentiated Thyroid Carcinoma of Follicular Cell Origin: Prognostic Significance of Histologic Subtypes.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
*Pediatric Differentiated Thyroid Carcinoma of Follicular Cell Origin: Prognostic Significance of Histologic Subtypes.* Thyroid. 2016 Feb;26(2):219-226 Authors: Balachandar S, La Quaglia M, Tuttle RM, Heller G, Ghossein RA, Sklar CA Abstract BACKGROUND: Thyroid cancers are rare in the pediatric age group, and unlike in adults, few data are available regarding the clinical implication of histologic subtypes in the pediatric population. The purpose of the current study was to determine the prognostic significance of histologic subtypes of differentiated thyroid cancer (DTC) in a la... περισσότερα »

A Rare Nasopharyngeal Teratoma Arising From the Vomer.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
*A Rare Nasopharyngeal Teratoma Arising From the Vomer.* J Craniofac Surg. 2016 Feb 5; Authors: Pang X, Kwon HJ, Shi B, Li C Abstract Teratomas are rare germ cell neoplasms derived from the 3 germinal layers (ectoderm, mesoderm, and endoderm). Nasopharyngeal teratoma is a very rare teratoma arising anywhere from the oronasal cavity, regarded as an expanding, avity filling lesion, with a high mortality rate because of severe airway obstruction, especially in the neonatal period and make up only 2% of all teratomas. The authors present a case of an infant girl with a single, finger...περισσότερα »

NEUROFIBROMATOSIS AS A GATEWAY TO BETTER TREATMENT FOR A VARIETY OF MALIGNANCIES.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
*NEUROFIBROMATOSIS AS A GATEWAY TO BETTER TREATMENT FOR A VARIETY OF MALIGNANCIES.* Prog Neurobiol. 2016 Feb 4; Authors: Bakker AC, La Rosa S, Sherman LS, Knight P, Lee H, Pancza P, Nievo M Abstract NF is a group of rare genetic disorders that can affect all races equally at an incidence from 1:3000 (NF1) to a log unit lower for NF2 and Schwannomatosis. Since the research community is reporting an increasing number of malignant cancers that carry mutations in the NF genes, the general interest of both the research and pharma community is increasing and the authors saw an opportu... περισσότερα »

Chondromyxoid fibroma of the pubic ramus: a case report and literature review.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
*Chondromyxoid fibroma of the pubic ramus: a case report and literature review.* Acta Orthop Traumatol Turc. 2016;50(1):115-9 Authors: Arıkan M, Toğral G, Yıldırım A, Aktaş E Abstract Chondromyxoid fibromas (CMF) are benign cartilaginous bone tumors which are found most frequently in the metaphyses of long bones. They comprise less than 1% of primary bone neoplasms. We report an interesting incidental case of a 43-year-old woman with a CMF of the left pubic ramus, presenting with complaints of gradual onset of left groin pain over a period of 2 years. According to radiological ex...περισσότερα »

Squamous cell carcinoma of the anal canal treated with chemoradiotherapy in a patient with HIV.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
*Squamous cell carcinoma of the anal canal treated with chemoradiotherapy in a patient with HIV.* Nihon Shokakibyo Gakkai Zasshi. 2016;113(2):254-62 Authors: Sugimoto A, Nakazuru S, Sakakibara Y, Nishio K, Yamada T, Ishida H, Yajima K, Uehira T, Mori K, Mita E Abstract Since the introduction of combination antiretroviral therapy (ART), the life expectancy has increased for patients infected with human immunodeficiency virus (HIV). This has been associated with reductions in the incidences of some AIDS-defining malignancies, such as Kaposi sarcoma and non-Hodgkin lymphoma, but has...περισσότερα »

Unresectable Middle Mediastinal Biphasic Pulmonary Blastoma.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Unresectable Middle Mediastinal Biphasic Pulmonary Blastoma.* Anticancer Res. 2015 Nov;35(11):6325-7 Authors: Gallo K, Brickman A, Warren WH, Gattuso P, Seder CW Abstract We report a case of a young male who presented with an unresectable, centrally-located classic biphasic pulmonary blastoma (CBPB) involving his bilateral mainstem bronchi and esophagus and a synchronous right testicular seminoma. CBPB is a rare and aggressive tumor that most commonly presents as a solitary mass in the periphery of the lung. Surgi... περισσότερα »

Surgical Management of Duodenal Gastrointestinal Stromal Tumors: A Case Report.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Surgical Management of Duodenal Gastrointestinal Stromal Tumors: A Case Report.* Anticancer Res. 2015 Nov;35(11):6321-4 Authors: Mrak K, Liegl-Atzwanger B, Haybaeck J, Petritsch W, Mischinger HJ, Kornprat P Abstract Gastrointestinal stromal tumors (GISTs) represent the most common mesenchymal tumor entity of the gastrointestinal tract. In fewer than 5% of cases, primary GISTs are located in the duodenum. Surgery represents the treatment of choice for localized tumor disease and remains challenging in GISTs locat...περισσότερα »

Ureteral Metastasis: Uncommon Manifestation in Prostate Cancer.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Ureteral Metastasis: Uncommon Manifestation in Prostate Cancer.* Anticancer Res. 2015 Nov;35(11):6317-20 Authors: Schallier D, Rappe B, Carprieaux M, Vandenbroucke F Abstract Ureteral metastasis from a primary prostate cancer is a rare event in the initial diagnosis and progression of prostate cancer. We report here the case of a 72- year-old patient who was treated for castration-resistant metastatic prostate cancer involving bone, intra-abdominal lymph nodes, bilateral adrenal glands, and a small distal ureteral...περισσότερα »

Adult Pleomorphic Rhabdomyosarcoma: A Multicentre Retrospective Study.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Adult Pleomorphic Rhabdomyosarcoma: A Multicentre Retrospective Study.* Anticancer Res. 2015 Nov;35(11):6213-7 Authors: Noujaim J, Thway K, Jones RL, Miah A, Khabra K, Langer R, Kasper B, Judson I, Benson C, Kollàr A Abstract BACKGROUND: Pleomorphic rhabdomyosarcoma (RMS) is a rare sub-type of RMS. Optimal treatment remains undefined. PATIENTS AND METHODS: Between 1995 and 2014, 45 patients were diagnosed and treated in three tertiary sarcoma Centers (United Kingdom, Switzerland and Germany). Treatment characteris... περισσότερα »

Severe Hypoglycemia Caused by Recurrent Sarcomatoid Carcinoma in the Pelvic Cavity: A Case Report.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Severe Hypoglycemia Caused by Recurrent Sarcomatoid Carcinoma in the Pelvic Cavity: A Case Report.* Medicine (Baltimore). 2015 Oct;94(42):e1577 Authors: Fang C, Fan CW, Yu YY, Wang C, Yang L, Li Y, Mo XM, Zhou ZG Abstract Nonislet cell tumor hypoglycemia (NICTH) is a paraneoplastic syndrome characterized by persistent, severe hypoglycemia in different tumor types of mesochymal or epithelial origin; however, NICTH is infrequently induced by sarcomatoid carcinoma (SC). Despite ...περισσότερα »

Ovarian clear cell carcinoma, outcomes by stage: the MSK experience.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Ovarian clear cell carcinoma, outcomes by stage: the MSK experience.* Gynecol Oncol. 2015 Nov;139(2):236-41 Authors: Shu CA, Zhou Q, Jotwani AR, Iasonos A, Leitao MM, Konner JA, Aghajanian CA Abstract OBJECTIVE: Ovarian clear cell carcinomas (OCCCs) are rare, and uncertainty exists as to the optimal treatment paradigm and validity of the FIGO staging system, especially in early-stage disease. METHODS: We performed a retrospective cohort study of all OCCC patients diagnosed and treated at Memorial Sloan Kettering C... περισσότερα »

Gestational trophoblastic neoplasia after spontaneous human chorionic gonadotropin normalization following molar pregnancy evacuation.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Gestational trophoblastic neoplasia after spontaneous human chorionic gonadotropin normalization following molar pregnancy evacuation.* Gynecol Oncol. 2015 Nov;139(2):283-7 Authors: Braga A, Maestá I, Matos M, Elias KM, Rizzo J, Viggiano MG Abstract OBJECTIVE: To evaluate the risk of gestational trophoblastic neoplasia (GTN) after spontaneous human chorionic gonadotropin normalization in postmolar follow-up. METHODS: Retrospective chart review of 2284 consecutive cases of hydatidiform mole with spontaneous normali... περισσότερα »

Sclerosing Pneumocytoma with a Wax-and-Wane Pattern of Growth: A Case Report on Computed Tomography and Magnetic Resonance Imaging Findings and a Literature Review.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--http://ift.tt/1V0fVJI] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Sclerosing Pneumocytoma with a Wax-and-Wane Pattern of Growth: A Case Report on Computed Tomography and Magnetic Resonance Imaging Findings and a Literature Review.* Korean J Radiol. 2015 Jul-Aug;16(4):947-50 Authors: Kim YP, Lee S, Park HS, Park CH, Kim TH Abstract Sclerosing pneumocytoma (SP) of the lung is a rare benign neoplasm. Here, we describe an unusual presentation of SP with a wax-and-wane pattern of growth in a 47-year-old woman. Tumor diameter decreased over a 3-year follow-...περισσότερα »

Sporadic Retinoblastoma and Pilocytic Astrocytoma: A Rare Association of Two Tumors.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Sporadic Retinoblastoma and Pilocytic Astrocytoma: A Rare Association of Two Tumors.* Pediatr Blood Cancer. 2015 Dec;62(12):2245-6 Authors: De Ioris MA, Carai A, Valente P, Angioni A, Randisi F, Cozza R, Romanzo A, Marras CE, Mastronuzzi A PMID: 26173175 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1V0fYoO via IFTTT

[Primary perivascular epitheloid cell tumour (PEComa) of the liver - is a new entity of the liver tumors?].

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--http://ift.tt/1SvbKVd] Related Articles *[Primary perivascular epitheloid cell tumour (PEComa) of the liver - is a new entity of the liver tumors?].* Z Gastroenterol. 2015 May;53(5):399-408 Authors: Panahova S, Rempp H, Sipos B, Malek NP, Boozari B Abstract Perivascular epitheloid cell tumor (PEComa) is a rare tumor, characterized by dual Expression of smooth muscle and melanocytic markers. Due to the development of diagnostic procedures, we now diagnose PEComa more often. We report about a case of PEComa of the liver as an accidental finding. We analyze the clinic... περισσότερα »

Inverting papilloma of the temporal bone: Report of four new cases and systematic review of the literature.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Inverting papilloma of the temporal bone: Report of four new cases and systematic review of the literature.* Laryngoscope. 2015 Nov;125(11):2576-83 Authors: Carlson ML, Sweeney AD, Modest MC, Van Gompel JJ, Haynes DS, Neff BA Abstract OBJECTIVES/HYPOTHESIS: Inverting papillomas (IPs) are benign locally invasive tumors that most commonly present within the sinonasal cavity. Temporal bone involvement is exceedingly rare, with fewer than 30 cases reported within the English literature to date. STUDY DESIGN: Case ser... περισσότερα »

Mucocoele and mucinous tumours of the appendix: A review of the literature.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Mucocoele and mucinous tumours of the appendix: A review of the literature.* Int J Surg. 2015 Jun;18:132-5 Authors: Rymer B, Forsythe RO, Husada G Abstract INTRODUCTION: Mucocoele of the appendix is rarely encountered but consultant general surgical and trainees must be aware of it as a differential diagnosis, due to the nuances associated with its management. We aimed to provide a comprehensive review of the current literature concerning this rare surgical pathology. METHODS: Search terms "appendi*", "tumour", "... περισσότερα »

Glioblastoma multiforme in Klippel-Trenaunay-Weber syndrome: a case report.

Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Glioblastoma multiforme in Klippel-Trenaunay-Weber syndrome: a case report.* J Med Case Rep. 2015;9:83 Authors: Yilmaz T, Cikla U, Kirst A, Baskaya MK Abstract INTRODUCTION: Klippel-Trenaunay-Weber syndrome (KTWS) is a rare syndrome in which patients usually present with cutaneous hemangiomas, venous varicosities, and bone and soft tissue hypertrophy of the affected limb. Intracranial lesions in patients with KTWS are extremely rare, and are generally reported as single cases in the lit... περισσότερα »

Platelet Rich Plasma OR Synthetic Graft

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Comparison of platelet rich plasma and synthetic graft material for bone regeneration after third molar extraction: *Dipesh B Nathani, Joyce Sequeira, B H. Sripathi Rao* Annals of Maxillofacial Surgery 2015 5(2):213-218 Aims: To compare the efficacy of Platelet rich plasma and synthetic graft material for bone regeneration after bilateral third molar extraction. Material and Methods: This study was conducted in 10 patients visiting the outpatient department of Oral & Maxillofacial Surgery, Yenepoya Dental College & Hospital. Patients requiring extraction of bilateral mandibular ...περισσότερα »

Blowout fracture-orbital floor reconstruction using costochondral cartilage causing pain, warping, and diplopia

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Blowout fracture-orbital floor reconstruction using costochondral cartilage causing pain, warping, and diplopia: *SM Balaji* Annals of Maxillofacial Surgery 2015 5(2):262-265 Orbital floor reconstruction is the most challenging component in the midfacial trauma management. Most often owing to the complexity of the fractures, the floor reconstruction requires grafts or other substitutes. Literature reveals several sources of autogenous sources of such grafts. Though most of the grafts are well taken and gives an ideal result, at certain instances, owing to the complex nature of t... περισσότερα »

Attractiveness

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Two-dimensional morphometric analysis of young Asian females to determine attractiveness: *Joseph John K Pothanikat, Ramdas Balakrishna, P Mahendra, J Neeta* Annals of Maxillofacial Surgery 2015 5(2):208-212 Introduction: Attractive people do not seem to consistently possess such ideal characteristics or share common features. There is no general consensus about the linear and angular characteristics that discriminate between attractive and normal persons. Aim: This study determines how young Asian women considered to be attractive differ in their twodimensional facial characte...περισσότερα »

Facial nerve reconstruction following radical parotidectomy and subtotal petrosectomy for advanced malignant parotid neoplasms

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Facial nerve reconstruction following radical parotidectomy and subtotal petrosectomy for advanced malignant parotid neoplasms: *Rocío Sánchez-Burgos, Teresa Gonzalez Otero, Luis Lassaletta, Javier Arias Gallo, Ignacio Navarro Cuellar, Miguel Burgueño García* Annals of Maxillofacial Surgery 2015 5(2):203-207 Introduction: To describe the oncological management and functional outcome of patients with advanced parotid malignant tumors undergoing facial nerve reconstruction after radical parotidectomy and subtotal petrosectomy. Materials and Methods: A combined approach was used to... περισσότερα »

Chondromyxoid fibroma of zygoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Chondromyxoid fibroma of zygoma in an elderly patient: A rare presentation: *Fernanda Pintor, Carlos Bahamondes, Omar Campos, Ariel Zivov* Annals of Maxillofacial Surgery 2015 5(2):244-248 Chondromyxoid fibroma (CF) is a benign bone tumor of cartilaginous origin and is considered the least common of cartilage-derived neoplasms. The lesion's most frequent location is in long bones, while involvement of craniofacial skeleton is extremely unusual. It generally appears in the second and third decade of life and most frequent in men. We present the case of a 68-year-old female with a... περισσότερα »

Inorganic bovine bone graft in periodontal defects

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Evaluation of inorganic bovine bone graft in periodontal defects after third molar surgery: *Daniela Guimaraes de Melo, Thiago de Santana Santos, Felipe Perraro Sehn, Emanuel Dias de Oliveira e Silva, Paulo Ricardo Saquete Martins-Filho, Ana Cláudia Amorim Gomes Dourado* Annals of Maxillofacial Surgery 2015 5(2):198-202 Aim: This study evaluated the e cacy of inorganic bovine bone graft (IBB) in periodontal defect after mandibular third molar (3M) surgery. Methods: The authors conducted a split-mouth, prospective, randomized, blinded, placebo-controlled clinical trial involving ... περισσότερα »

Lipoma of the palate

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
A common tumor in an uncommon location: Lipoma of the palate: *Satvinder Singh Bakshi, Madhu Priya, V Nirmal Coumare, S Vijayasundaram, Lavanya Karanam* Annals of Maxillofacial Surgery 2015 5(2):237-239 Lipomas are benign mesenchymal neoplasms that originate in mature adipose cells. Although rare in the oral cavity, they are mostly seen in the buccal mucosa, tongue, and gingiva; those arising from the palate are very rare. We report a case of a 42-year-old male patient with a large intraoral swelling that on excision was reported as a lipoma. Oral lipomas are rare and those occ...περισσότερα »

Reconstruction in oral malignancy: Factors affecting morbidity of various procedures

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Reconstruction in oral malignancy: Factors affecting morbidity of various procedures: *Suvadip Chakrabarti, Preeti Rihal Chakrabarti, Sanjay M Desai, Deepak Agrawal, Dharmendra Y Mehta, Mayank Pancholi* Annals of Maxillofacial Surgery 2015 5(2):191-197 Aims and Objective: (1) To study the age and sex distribution of patient with oral malignancies. (2) To analyze various types of surgery performed. (3) Evaluation of reconstruction and factors affecting complications and its relation to the type of reconstruction. Materials and Methods: Cases of oral malignancies, undergoing surge... περισσότερα »

Bioabsorbable internal fixation for maxillofacial fractures

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Perspectives of patients about bioabsorbable internal fixation for maxillofacial fractures: *Constantin Landes, Sebastian H Hoefer, Tereza Richards, Felix Walcher, Robert Sader* Annals of Maxillofacial Surgery 2015 5(2):185-190 Purpose: Resorbable/bioabsorbable internal fixation provides effective treatment for maxillofacial fractures and avoids the need for metal hardware removal. We evaluated the initial knowledge, attitudes, subjective demand, and treatment satisfaction of patients concerning bioabsorbable osteofixation for maxillofacial trauma. Materials and Methods: From Ma... περισσότερα »

Keutel syndrome: Augmentation of the nose with serial fat grafting

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Keutel syndrome: Augmentation of the nose with serial fat grafting: *Sinem Ciloglu, Alpay Duran, Ahmet Kursat Yigit, Hasan Buyukdogan, Ekrem Keskin* Annals of Maxillofacial Surgery 2015 5(2):287-288 Keutel syndrome is an extremely rare autosomal recessive hereditary syndrome and is caused by mutations within the matrix Gla protein gene.[1], [2] Here, we report a patient with Keutel syndrome whose soft tissue deficiency and nasal deformity were corrected by soft tissue augmentation accomplished through serial fat grafting. A 20-year-old female with Keutel syndrome was admitted to ... περισσότερα »

Buccal fat pad free graft in regenerative treatment of peri-implantitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
The use of Buccal fat pad free graft in regenerative treatment of peri-implantitis: A new and predictable technique: *Fares Kablan* Annals of Maxillofacial Surgery 2015 5(2):179-184 Introduction: Peri-implantitis is a common condition, but no particular treatment protocol has shown to be definitively effective. Fat tissue in the oral cavity is widely available and easily accessed. The aim of the current study is to present a novel technique in the treatment of peri-implant lesions, utilizing a free fat tissue graft from the buccal fat pad (BFP). Patients and Methods: Free fat gr... περισσότερα »

Posteriorly based lateral tongue flap for reconstruction of large palatal-alveolar fistulas in cleft patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Posteriorly based lateral tongue flap for reconstruction of large palatal-alveolar fistulas in cleft patients: *Amin Rahpeyma, Saeedeh Khajehahmadi* Annals of Maxillofacial Surgery 2015 5(2):174-178 Background: Large palatal fistula in cleft patients is a difficult situation, especially with previous multiple surgeries, which have led to severe scars in the palatal mucosa. Tongue flaps are useful aids in such situations. Materials and Methods: Seven cleft patients who were reconstructed by posteriorly based lateral tongue flap between 2005 and 2012 were studied. Variables such ... περισσότερα »

Isolated abducens nerve paralysis in maxillofacial trauma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
A case of isolated abducens nerve paralysis in maxillofacial trauma: *Elif Seda Keskin, Ekrem Keskin, Bekir Atik, Abdülkadir Koçer* Annals of Maxillofacial Surgery 2015 5(2):258-261 Nervus abducens is a pure motor nerve located in the pons. It retracts the eyeball laterally by stimulating rectus lateralis muscle. In case of their paralysis, diplopia and restriction in the eye movements while looking sideways, are seen. Since the same signs are seen due to the muscle entrapment in blowout fractures, its differential diagnosis has importance in terms of the treatment protocol and ... περισσότερα »

Laryngeal Leiomyosarcoma (LMS)

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
A case of laryngeal leiomyosarcoma and review of the literature: *Ömer Tarik Selçuk, Levent Renda, Bekir Erol, ?stün Osma, Hülya Eyigor, Hülya Öztürk* Annals of Maxillofacial Surgery 2015 5(2):274-276 Leiomyosarcoma (LMS) of the larynx is a very rare malignancy that originates from blood vessel, smooth muscle or from the heterotopic mesenchymal tissue in the larynx. The histological diagnosis of LMS depends on the immunohistochemical investigation. The case is here presented of an 82-year-old man with shortness of breath and hoarseness. Indirect laryngoscopy showed a pedunculat...περισσότερα »

Etiology and comorbid diseases associated with Ludwig's Angina

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Retrospective analysis of etiology and comorbid diseases associated with Ludwig's Angina: *Andrew Botha, Fred Jacobs, Corne Postma* Annals of Maxillofacial Surgery 2015 5(2):168-173 Introduction: Ludwig's angina (LA) still presents regularly at our tertiary academic hospital. Various etiologies and comorbid diseases are documented worldwide, but the South African population has not been studied. Aim: To establish whether LA cases presenting to the department are different from international reports regarding etiology and comorbidities. Settings and Design: Retrospective analysis... περισσότερα »

Two stage ear/microtia reconstruction using costal cartilage

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Two stage ear/microtia reconstruction using costal cartilage: *SM Balaji* Annals of Maxillofacial Surgery 2015 5(2):163-167 Background: Reconstruction of Grade III microtia is a challenging entity in maxillofacial esthetic rehabilitation. Several advocacies and philosophies exist in this field. The aim of the manuscript is to present a single South Indian Experience with Ear reconstruction among South Indian Population.Materials and Methods: Retrospective analysis of unilateral Grade III microtia reconstruction was performed. Using a set of predefined inclusion and exclusion cri... περισσότερα »

Carcinosarcoma of parotid gland (malignant mixed tumor)

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Carcinosarcoma of parotid gland (malignant mixed tumor): *Duan Feng, Nyimi Bushabu Fidele, Mansthumba Milolo Agustin, Guan Jian, Sekele Isouradi Bourleyi, Lamwe Augustin, Ngueji Kakubu Olivier* Annals of Maxillofacial Surgery 2015 5(2):240-243 Salivary gland carcinosarcoma is a rare neoplasm; with a poor prognosis. The most common epithelial components are adenocarcinoma or squamous cell carcinoma, whereas the most common mesenchymal components are chondrosarcoma. It should not be confused with the most common carcinoma ex-pleomorphic adenoma, in which the epithelial component a... περισσότερα »

Margin to tumor thickness ratio – A predictor of local recurrence and survival in oral squamous cell carcinoma

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Margin to tumor thickness ratio – A predictor of local recurrence and survival in oral squamous cell carcinoma: Surgical resection is the mainstay of treatment for oral squamous cell carcinoma (OSCC). Satisfactory oncologic resections require negative and adequate resection margins. A microscopic margin of 5mm has traditionally been accepted as adequate for various oral cavity sub-sites [1,2]. This definition, however, of adequate surgical resection remains controversial as some authors propose 2mm to be sufficient [3] while others advocate for more than 7mm [4]. Ch’ng et al. [5] an... περισσότερα »

Carcinosarcoma of parotid gland (malignant mixed tumor)

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 16 δευτερόλεπτα
Carcinosarcoma of parotid gland (malignant mixed tumor): *Duan Feng, Nyimi Bushabu Fidele, Mansthumba Milolo Agustin, Guan Jian, Sekele Isouradi Bourleyi, Lamwe Augustin, Ngueji Kakubu Olivier* Annals of Maxillofacial Surgery 2015 5(2):240-243 Salivary gland carcinosarcoma is a rare neoplasm; with a poor prognosis. The most common epithelial components are adenocarcinoma or squamous cell carcinoma, whereas the most common mesenchymal components are chondrosarcoma. It should not be confused with the most common carcinoma ex-pleomorphic adenoma, in which the epithelial component a... περισσότερα »

Complications of facial rejuvenation surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Complications of facial rejuvenation surgery: *SM Balaji* Annals of Maxillofacial Surgery 2015 5(2):145-145 The reversing of aging through surgical methods is the current “hot topic” in maxillofacial surgery. There are numerous training programs, short-term courses and “hands-on” programs being offered in conjunction with several thematic meetings and conferences. Undoubtedly, OMF surgeons are also being taken into the field. Usage of ancillary techniques like boutillum toxins is also gaining widespread use. These technique sensitive materials and procedures are akin to the “Swo... περισσότερα »

Guiding flange prosthesis in hemimandibulectomy patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Treatment outcome with guiding flange prosthesis in hemimandibulectomy patients: Case series of three patients: *Sushil Kar, Arvind Tripathi, Riti Madhok* Annals of Maxillofacial Surgery 2015 5(2):266-270 There are various indications that may necessitate partial or complete resection of the mandible, from trauma to congenital deformities. However, the most prevalent indication that requires surgical resection of the mandible along with the involved adjacent oral structures is the presence of a locally aggressive neoplastic growth. The resultant continuity defect leads to an al... περισσότερα »

Perpendicular serial maxillary distraction osteogenesis in cleft lip and palate patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Perpendicular serial maxillary distraction osteogenesis in cleft lip and palate patients: *Leena P Ylikontiola, George K Sándor, Virpi Harila* Annals of Maxillofacial Surgery 2015 5(2):148-157 Background: Cleft lip and palate patients often have a retruded maxilla with a severely narrowed deficient maxillary arch. This report aims to describe the management of severe maxillary retrusion and constriction in cleft lip and palate patients using distraction osteogenesis applied in serial sequence in two directions perpendicular to each other. Materials and Methods: Two adult male cl... περισσότερα »

Nonsyndromic orofacial clefts,The MSX1 gene polymorphisms rs12532 and rs1001179

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
The MSX1 gene polymorphisms rs12532 and rs1001179 confer an increased risk of nonsyndromic orofacial clefts via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 5 February 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Fang Luan, Fengling Sun, Chao Xu, Haixia Zhang PurposeIn this study, we used a meta-analysis–based approach to examine the association between muscle segment homeobox 1 (MSX1) gene polymorphisms and nonsyndromic orofacial clefts (NSOC).Material and MethodsScientific literature databases were exhaustive... περισσότερα »

Reconstruction of anterior maxillary defect with buccal pad fat after excision of melanotic neuroectodermal tumor of infancy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Reconstruction of anterior maxillary defect with buccal pad fat after excision of melanotic neuroectodermal tumor of infancy: *Dinesh Kumar, Vidya Rattan, Sachin Rai, Shikha Yadav, Gyana Ranjan Sahu* Annals of Maxillofacial Surgery 2015 5(2):234-236 This paper highlights a rare case of melanotic neuroectodermal tumor of infancy involving the anterior maxilla in a 3-month-old infant. The tumor was excised completely, and the defect was reconstructed with a bilateral buccal pad of fat. The patient has been followed for 2 years without any evidence of recurrence. We propose that fo... περισσότερα »

Killian's polyp mimicking malignant tumor

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Killian's polyp mimicking malignant tumor: *Jagdeep S Thakur, Avinash Chaitanya, RS Minhas, RK Azad, DR Sharma, NK Mohindroo* Annals of Maxillofacial Surgery 2015 5(2):281-283 Killian polyp is predominantly found in children and any sinonasal tumor in elderly presenting with epistaxis and pain usually indicates malignant growth until proved otherwise. We present an unusual case of Killian polyp in an elderly patient that behaved as a malignant tumor. This case report reminded us that paranasal sinuses are still dark hollow mysterious cavities, and we should take utmost clinical ... περισσότερα »

Maxillary Expansion and Maxillomandibular Expansion for Adult OSA

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
: A Systematic Review and Meta-Analysis via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 6 February 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Jose Abdullatif, Victor Certal, Soroush Zaghi, Sungjin A. Song, Edward T. Chang, M. Boyd Gillespie, Macario Camacho ObjectiveThis study sought to systematically review the international literature for articles evaluating maxillary expansion and maxillomandibular expansion as treatments for obstructive sleep apnea (OSA) in adults and to perform a meta-analysis.Data Sour...περισσότερα »

Tongue entrapment

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
*Tongue entrapment within the lid of a plastic bottle* *via British Journal of Oral and Maxillofacial Surgery* *[image: Tongue trapped inside the lid of a plastic bottle.] [image: Equipment used to remove the lid: 10ml syringe (top), Vasofix® safety cannula ...]Source:British Journal of Oral and Maxillofacial SurgeryAuthor(s): Yusuf Gadiwalla, Luis Bruzual, Daniel Altieri, Joanne Taylor, Nicholas Whear* *Girl has emergency surgery after tongue gets STUCK in metal water ...* *www.dailymail.co.uk634 × 350Αναζήτηση βάσει εικόνας* *Expanded: The girl's tongue expanded dramatically after ...περισσότερα »

Dopamine depletion affects communicative intentionality in Parkinson’s disease patients: evidence from action kinematics

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 18 δευτερόλεπτα
Publication date: Available online 9 February 2016 *Source:*Cortex Author(s): Elisa Straulino, Tomaso Scaravilli, Umberto Castiello Appropriate communication is at the heart of successful, healthy social interactions in humans. Deficits in social communication are a hallmark of several neurological and psychiatric disorders. Yet, very little research has been devoted to understanding the mechanisms underlying these issues. It has been suggested that dopamine is a candidate neurotransmitter system involved in stimulating communication in individuals that are not highly motivated to c...περισσότερα »

News and Events

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
Volume 92, Issue 2, February 2016, pages 116-116<br>10.3109/09553002.2016.1140388<br> from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1LdXPhy via IFTTT

Refining the head and neck cancer referral guidelines

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
: a two centre analysis of 4715 referrals via British Journal of Oral and Maxillofacial Surgery Publication date: February 2016 *Source:*British Journal of Oral and Maxillofacial Surgery, Volume 54, Issue 2 Author(s): Theofano Tikka, Paul Pracy, Vinidh Paleri Our aim was to identify the set of referral criteria that will offer optimal diagnostic efficacy in patients suspected to have head and neck cancer (HNC) in the primary care setting. We analysed the referral criteria and outcomes from two tertiary care cancer centres in the United Kingdom. Between 2007 and 2010, 4715 patients were... περισσότερα »

Diffusion-Weighted Magnetic Resonance Imaging to Differentiate Malignant from Benign Gallbladder Disorders

Publication date: Available online 8 February 2016 Source:European Journal of Radiology Author(s): Yoshio Kitazume, Shin-ichi Taura, Shuichiro Nakaminato, Osamu Noguchi, Yukiyoshi Masaki, Ichiro Kasahara, Mitsuhiro Kishino, Ukihide Tateishi PurposeTo retrospectively evaluate the utility of apparent diffusion coefficient (ADC) and lesion to spinal cord ratio (LSR) in diffusion-weighted magnetic resonance (MR) imaging (DWI) as compared with […]

MRI of the lung using the PROPELLER technique: Artifact reduction, better image quality and improved nodule detection

Publication date: April 2016 Source:European Journal of Radiology, Volume 85, Issue 4 Author(s): Michael Meier-Schroers, Guido Kukuk, Rami Homsi, Dirk Skowasch, Hans Heinz Schild, Daniel Thomas PurposeTo evaluate the benefit of the PROPELLER technique (Periodically Rotated Overlapping ParallEL Lines with Enhanced Reconstruction, MultiVane, MV) for MR imaging of the lung.Materials and Methods30 Participants of a […]

Corrigendum to “Computerized analysis of calcification of thyroid nodules as visualized by ultrasonography” Eur. J. Radiol. 84 (2015) 1949–1953

Publication date: Available online 8 February 2016 Source:European Journal of Radiology Author(s): Woo Jung Choi, Jeong Seon Park, Kwang Gi Kim, Soo-Yeon Kim, Hye Ryoung Koo, Young-Jun Lee from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XfIQe0 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Candida-induced denture stomatitis : Rechargeable anticandidal denture material with sustained release in saliva

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Rechargeable anticandidal denture material with sustained release in saliva by Andrey Malakhov, Jianchuan Wen, Bin-Xian Zhang, Hanzhou Wang, Hui Geng, Xiao-Dong Chen, Yuyu Sun, Chih-Ko Yehvia Oral Diseases Abstract Objective *Candida*-induced denture stomatitis is a common debilitating problem among denture wearers. Previously, we described the fabrication of a new denture material that released antifungal drugs when immersed in phosphate buffered saline. Here, we use more clinically relevant immersion conditions (human saliva; 37°C) and measure miconazole release and bioactivity. Mate... περισσότερα »

Mandibular distraction osteogenesis for the management of upper airway obstruction in children with micrognathia

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
: a systematic review via Oral and Maxillofacial Surgery Publication date: Available online 8 February 2016 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): O. Breik, D. Tivey, K. Umapathysivam, P. Anderson Mandibular distraction osteogenesis (MDO) is increasingly used for neonates and infants with upper airway obstruction secondary to micrognathia. This systematic review was conducted to determine the effectiveness of MDO in the treatment of airway obstruction. The databases searched included PubMed, Embase, Scopus, and grey literature sources. The inclusion ... περισσότερα »

Palatal Ulcers

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Clinicopathologic conference Supplemental material Bilateral palatal ulcers in a patient on immunosuppressive therapy http://dx.doi.org/10.1016/j.oooo.2015.08.011 Anastasia Shamsuyarova, MDa, , , Zeina Ghorab, MD, MScb, Kevin Higgins, MD, MSc, FRCSCc, Hagen Klieb, DMD, MSc, FRCD(C)d a Department of Dermatology, University of Toronto, Toronto, Ontario, Canada b Department of Anatomic Pathology, University of Toronto, Toronto, Ontario, Canada c Department of Otolaryngology, University of Toronto, Toronto, Ontario, Canada d Department of Anatomic Pathology and Department of Dentistry, Unive... περισσότερα »

Cytotoxic effects of SMAC-mimetic compound LCL161 in head and neck cancer cell lines

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Cytotoxic effects of SMAC-mimetic compound LCL161 in head and neck cancer cell lines: Abstract ObjectivesHead and neck squamous cell carcinoma (HNSCC) is one of the most common tumor entities worldwide. Unfortunately, recent drug developments in other fields of oncology have yielded no efficacy in the treatment of oral squamous cell carcinoma. As a new starting point, we investigated the impact of Fas ligand (FasL) and the SMAC-mimetic compound LCL161 in mono- and combination treatment in HNSCC cell lines. MethodsFive different cell lines of HNSCC were treated with FasL and LCL1...περισσότερα »

Basal cell adenoma with S-100 positive stroma

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
: a case report and literature review via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: March 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 Author(s): Emanuela Ortolani, Antonella Polimeni, Libero Lauriola, Antonella Coli Basal cell adenoma (BCA) of the salivary gland with presence of abundant S-100–positive stromal cells has been rarely reported. A case occurring in a 75-year-old man is presented here, as well as a review of the literature on the subject. The patient presented with a nodule in the ...περισσότερα »

Spindle cell variant of ameloblastic carcinoma

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
: a case report and literature review via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: March 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 Author(s): Yuki Matsushita, Shuichi Fujita, Souichi Yanamoto, Shin-ichi Yamada, Satoshi Rokutanda, Kentaro Yamashita, Tohru Ikeda, Masahiro Umeda Spindle cell variant of ameloblastic carcinoma is an extremely rare tumor. Severe dedifferentiated spindle cell variants are diagnostically challenging, particularly in small biopsy specimens. Here, we report a case of ...περισσότερα »

The Automatic Neuroscientist: A framework for optimizing experimental design with closed-loop real-time fMRI

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 37 δευτερόλεπτα
[image: S10538119.gif] Publication date: 1 April 2016 *Source:*NeuroImage, Volume 129 Author(s): Romy Lorenz, Ricardo Pio Monti, Inês R. Violante, Christoforos Anagnostopoulos, Aldo A. Faisal, Giovanni Montana, Robert Leech Functional neuroimaging typically explores how a particular task activates a set of brain regions. Importantly though, the same neural system can be activated by inherently different tasks. To date, there is no approach available that systematically explores whether and how distinct tasks probe the same neural system. Here, we propose and validate an alternative ... περισσότερα »

The activation of interactive attentional networks

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 37 δευτερόλεπτα
[image: S10538119.gif] Publication date: 1 April 2016 *Source:*NeuroImage, Volume 129 Author(s): Bin Xuan, Melissa-Ann Mackie, Alfredo Spagna, Tingting Wu, Yanghua Tian, Patrick R. Hof, Jin Fan Attention can be conceptualized as comprising the functions of alerting, orienting, and executive control. Although the independence of these functions has been demonstrated, the neural mechanisms underlying their interactions remain unclear. Using the revised attention network test and functional magnetic resonance imaging, we examined cortical and subcortical activity related to these atten...περισσότερα »

State-space model with deep learning for functional dynamics estimation in resting-state fMRI

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 37 δευτερόλεπτα
[image: S10538119.gif] Publication date: 1 April 2016 *Source:*NeuroImage, Volume 129 Author(s): Heung-Il Suk, Chong-Yaw Wee, Seong-Whan Lee, Dinggang Shen Studies on resting-state functional Magnetic Resonance Imaging (rs-fMRI) have shown that different brain regions still actively interact with each other while a subject is at rest, and such functional interaction is not stationary but changes over time. In terms of a large-scale brain network, in this paper, we focus on time-varying patterns of functional networks, i.e., functional dynamics, inherent in rs-fMRI, which is one of th... περισσότερα »

Cytotoxic effects of SMAC-mimetic compound LCL161 in head and neck cancer cell lines

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Cytotoxic effects of SMAC-mimetic compound LCL161 in head and neck cancer cell lines: Abstract ObjectivesHead and neck squamous cell carcinoma (HNSCC) is one of the most common tumor entities worldwide. Unfortunately, recent drug developments in other fields of oncology have yielded no efficacy in the treatment of oral squamous cell carcinoma. As a new starting point, we investigated the impact of Fas ligand (FasL) and the SMAC-mimetic compound LCL161 in mono- and combination treatment in HNSCC cell lines. MethodsFive different cell lines of HNSCC were treated with FasL and LCL1...περισσότερα »

Serum-free grown adipose-derived stem cells (ADSC)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 41 δευτερόλεπτα
In vivo bone regeneration on titanium devices using serum-free grown adipose-derived stem cells, in a sheep femur model by Diogo Godoy Zanicotti, Dawn Elizabeth Coates, Warwick John Duncan via Clinical Oral Implants Research Abstract Aim The aim of this study was to investigate the capacity of adipose-derived stem cells (ADSC), grown in serum-free conditions, to regenerate bone around titanium discs with different titanium surfaces. Material and methods Ovine ADSC (oADSC) were isolated from seven sheep and cultured using serum-free and osteogenic conditions. Prior to *in vivo* testing,... περισσότερα »

Bone Tissue Engineering

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 43 δευτερόλεπτα
Surface Modification of 3D-Printed Porous Scaffolds via Mussel-Inspired Polydopamine and Effective Immobilization of rhBMP-2 to Promote Osteogenic Differentiation for via Acta Biomaterialia Publication date: Available online 8 February 2016 *Source:*Acta Biomaterialia Author(s): Sang Jin Lee, Donghyun Lee, Taek Rim Yoon, Hyung Keun Kim, Ha Hyeon Jo, Ji Sun Park, Jun Hee Lee, Wan Doo Kim, Il Keun Kwon, Su A Park For tissue engineering, a bio-porous scaffold which is applied to bone-tissue regeneration should provide the hydrophilicity for cell attachment as well as provide for the capa... περισσότερα »

Guided Bone Regeneration

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 43 δευτερόλεπτα
*Open Dent J. doi: 10.2174/1874210601408010056PMCID: PMC4040931*Suppl 1 Mechanisms of Guided Bone Regeneration: A Review *Jie Liu# and David G Kerns** Department of Periodontics, Baylor College of Dentistry, Texas A&amp;M University, Dallas, TX *#Private Practice, Houston, TX* **Address correspondence to this author at the Texas A&amp;M University, Baylor College of Dentistry, Department of Periodontics, 3302 Gaston Ave. Dallas, TX 75246; Tel: 214-828-8282; Fax: 214-874-4563; E-mail: ude.cshmat.dcb@snrekd* *Go to:* INTRODUCTION *Implant therapy to restore an edentulous site has gained more p... περισσότερα »

Guided Bone and Tissue Regeneration

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 46 δευτερόλεπτα
Guided bone and tissue regeneration *From Wikipedia, the free encyclopedia* Guided bone and tissue regeneration *Intervention* MeSH *D048091* *Guided bone regeneration or GBR, and guided tissue regeneration or GTR are dental surgical procedures that use barrier membranes to direct the growth of new bone and gingival tissue at sites with insufficient volumes or dimensions of bone or gingiva for proper function, esthetics or prosthetic restoration.* *GBR is similar to guided tissue regeneration (GTR) but is focused on development of hard tissues in addition to the soft tissues of the p...περισσότερα »

Guided bone regeneration and abutment connection augment the buccal soft tissue contour

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 47 δευτερόλεπτα
: 3-year results of a prospective comparative clinical study by Goran I. Benic, Yanjun Ge, German O. Gallucci, Ronald E. Jung, David Schneider, Christoph H. F. Hämmerle via Clinical Oral Implants Research [image: cover.gif?v=1&amp;s=be74442fea687c39b7fdfa63] Abstract Aim To test whether implant placement with simultaneous guided bone regeneration (GBR) differs from implant placement without GBR regarding the change in marginal mucosal contour. Materials and methods In 28 patients, single implants were placed &gt;4 months after tooth extraction. Eighteen implants were completely surrounded by... περισσότερα »

The Journal of Laryngology &amp; Otology

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 49 δευτερόλεπτα
*Main ArticleThe effects of different suture materials in the nasal cavity previewA Durmaz, A Kilic, R Gumral, U Yildizoglu and B PolatThe Journal of Laryngology &amp; Otology / FirstView ArticlesCopyright © JLO (1984) Limited 2016 DOI: http://dx.doi.org/10.1017/S002221511600027X (About DOI), 5 pages. Published online: 09 Φεβρουάριος 2016 - Abstract- Buy This Article $45,00 / £30,00- Related Articles[image: Article has an altmetric score of 2]Clinical RecordCochlear implantation is a therapeutic option for s... περισσότερα »

Integration of Intention and Outcome for Moral Judgment in Frontotemporal Dementia: Brain Structural Signatures

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 50 δευτερόλεπτα
Background: Moral judgment has been proposed to rely on a distributed brain network. This function is impaired in behavioral variant frontotemporal dementia (bvFTD), a condition involving damage to some regions of this network. However, no studies have investigated moral judgment in bvFTD via structural neuroimaging. Methods: We compared the performance of 21 bvFTD patients and… Continue reading Integration of Intention and Outcome for Moral Judgment in Frontotemporal Dementia: Brain Structural Signatures

Anti-Inflammatory and Antioxidant Actions of N-Arachidonoyl Serotonin in RAW264.7 Cells

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 50 δευτερόλεπτα
The purpose of this study is to evaluate the effect of N-arachidonoyl serotonin (NA-5HT) on inflammatory response or oxidative stress in RAW264.7 cells exposed to lipopolysaccharide (LPS). When RAW264.7 cells were pre-incubated with NA-5HT before LPS treatment, NA-5HT was found to suppress LPS-induced formation of nitric oxide (NO), tumor necrosis factor-α or interleukins as well… Continue reading Anti-Inflammatory and Antioxidant Actions of N-Arachidonoyl Serotonin in RAW264.7 Cells

Topical Application of Honey on Surgical Wounds: A Randomized Clinical Trial

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 50 δευτερόλεπτα
Forsch Komplementmed from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1V0phVy via IFTTT

Mehr Daten? Mehr denken? Umdenken!

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 50 δευτερόλεπτα
Forsch Komplementmed from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1onTSCc via IFTTT

Prophylaxe kardiovaskulärer Erkrankungen bei Typ-2-Diabetes

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 50 δευτερόλεπτα
Das Gefäßrisiko mindern Das erhöhte kardiovaskuläre Risiko von Patienten mit Typ-2-Diabetes macht schon früh im Krankheitsverlauf Präventionsmaßnahmen notwendig. Abhängig von der Ko- und Folgemorbidität steht eine Reihe von Optionen zur Verfügung. Wir fassen die wichtigsten Erkenntnisse der letzten Jahren zusammen. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1V0phFf via IFTTT

Über Locked-in, Wachkoma und die Karriere des toten Lachses

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 50 δευτερόλεπτα
Neurointensivmedizin in den Medien Die neurologische Intensivmedizin hat in der Öffentlichkeit kein gutes Image. Falsche Begriffe und falsche Experten sorgen für überzogene Erwartungen – davon ist die Schlaganfall-Koryphäe Professor Werner Hacke überzeugt. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1LdR3sc via IFTTT

Convection enhanced delivery of chemotherapy to paediatric brain stem tumours

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 50 δευτερόλεπτα
Prof Gill talks to ecancertv at Children with Cancer UK’s workshop on Drug Delivery in Paediatric Brain Tumours in London, UK. In the interview he discusses early clinical experience of intermittently delivering carboplatin directly to paediatric… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1TPPZSC via IFTTT

Intra-arterial chemotherapy methods for CNS tumours

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 50 δευτερόλεπτα
Dr Pearl talks to ecancertv at Children with Cancer UK’s workshop on Drug Delivery in Paediatric Brain Tumours in London, UK. In the interview she discusses her work on intra-arterial chemotherapy for central nervous system tumours. Dr Pearl explains… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/20lNJCs via IFTTT

Treating relapsed brain tumours with anti-angiogenic metronomic therapy

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 50 δευτερόλεπτα
Dr Slavc talks to ecancertv at Children with Cancer UK’s workshop on Drug Delivery in Paediatric Brain Tumours in London, UK. In the interview she discusses the use of metronomic anti-angiogenic therapy in patients with relapsed brain… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1TPQ0Wt via IFTTT

The “net” of the Internet: Risk Factors for Cyberbullying among Secondary-School Students in Greece

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 50 δευτερόλεπτα
Abstract Cyberbullying is one of the most common threats an adolescent might face online with serious negative consequences at the social, emotional and educational level. Despite the intense study of the phenomenon over the past decade, most researchers ask for new directions in research that will focus on risk and protective factors. This study attempted… Continue reading The “net” of the Internet: Risk Factors for Cyberbullying among Secondary-School Students in Greece

Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.

Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients. Int J Audiol. 2016 Feb 6;:1-6 Authors: English R, Plant K, Maciejczyk M, Cowan R Abstract OBJECTIVE: For a group of cochlear implant recipients, who use hearing aids in the contralateral ear, the benefit of NAL-NL2 relative […]

Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-β1a and Circulating Proinflammatory Cytokines in Relapsing–Remitting Multiple Sclerosis

Abstract Palmitoylethanolamide (PEA) is an endogenous lipid mediator known to reduce pain and inflammation. However, only limited clinical studies have evaluated the effects of PEA in neuroinflammatory and neurodegenerative diseases. Multiple sclerosis (MS) is a chronic autoimmune and inflammatory disease of the central nervous system. Although subcutaneous administration of interferon (IFN)-β1a is approved as first-line […]

Diffusion-Weighted Magnetic Resonance Imaging to Differentiate Malignant from Benign Gallbladder Disorders

Publication date: Available online 8 February 2016 Source:European Journal of Radiology Author(s): Yoshio Kitazume, Shin-ichi Taura, Shuichiro Nakaminato, Osamu Noguchi, Yukiyoshi Masaki, Ichiro Kasahara, Mitsuhiro Kishino, Ukihide Tateishi PurposeTo retrospectively evaluate the utility of apparent diffusion coefficient (ADC) and lesion to spinal cord ratio (LSR) in diffusion-weighted magnetic resonance (MR) imaging (DWI) as compared with […]

MRI of the lung using the PROPELLER technique: Artifact reduction, better image quality and improved nodule detection

Publication date: April 2016 Source:European Journal of Radiology, Volume 85, Issue 4 Author(s): Michael Meier-Schroers, Guido Kukuk, Rami Homsi, Dirk Skowasch, Hans Heinz Schild, Daniel Thomas PurposeTo evaluate the benefit of the PROPELLER technique (Periodically Rotated Overlapping ParallEL Lines with Enhanced Reconstruction, MultiVane, MV) for MR imaging of the lung.Materials and Methods30 Participants of a […]

Higher Fines—Fewer Traffic Offences? A Multi-Site Observational Study

Abstract Assess the impact of a 100-per cent increase of fines on compliance with speed-limits (50 km/h) and parking regulations in urban areas. Norm violations were measured through standardized observations in all five major cities in Switzerland before and after fines had been raised by 100 % or more at two pre- and two post-intervention […]

Corrigendum to “Computerized analysis of calcification of thyroid nodules as visualized by ultrasonography” Eur. J. Radiol. 84 (2015) 1949–1953

Publication date: Available online 8 February 2016 Source:European Journal of Radiology Author(s): Woo Jung Choi, Jeong Seon Park, Kwang Gi Kim, Soo-Yeon Kim, Hye Ryoung Koo, Young-Jun Lee from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XfIQe0 via IFTTT

MR Imaging of Skeletal Muscle Signal alterations: Systematic approach to evaluation

Publication date: Available online 8 February 2016 Source:European Journal of Radiology Author(s): Yogesh Kumar, Vibhor Wadhwa, Lauren Phillips, Parham Pezeshk, Avneesh Chhabra Muscle edema or edema-like signal alterations are commonly encountered findings in musculoskeletal magnetic resonance (MR) imaging. Although such signal alterations are very sensitive for detection of the underlying muscle pathology, these are often […]

miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Simon Raffel, Andreas Trumpp Leukemic stem cells (LSCs) are resistant to conventional chemotherapy and promote acute myeloid leukemia (AML) progression and recurrence. In this issue of Cancer Cell, Lechman and colleagues (2016) identify the microRNA miR-126 as a regulator of PI3K-AKT-mTOR and CDK3 […]

Defining the Molecular Alterations of Ampullary Carcinoma

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Jing Tan, Patrick Tan, Bin Tean Teh Ampullary carcinomas represent a group of heterogeneous tumors that can be histologically divided into two subtypes with distinct pathogenic and clinical characteristics. Yachida et al. (2016) and Gingras et al. (2016) now report the genomic landscape […]

Fall of the Optical Wall: Freedom from the Tyranny of the Microscope Improves Glioma Risk Stratification

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Vijay Ramaswamy, Michael D. Taylor A recent study uses an integrated genomic approach to identify biologically defined subgroups of adult diffuse glioma. These results further lay the foundation for a pathological classification scheme for gliomas that incorporates both histology and molecular biomarkers, which […]

Angiogenesis inhibitor; +28 new citations

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
28 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Angiogenesis inhibitor* These pubmed results were generated on 2016/02/09 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1O1arZq via IFTTT

Modified alginate and gelatin cross-linked hydrogels for soft tissue adhesive.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Modified alginate and gelatin cross-linked hydrogels for soft tissue adhesive.* Artif Cells Nanomed Biotechnol. 2016 Feb 8;:1-8 Authors: Yuan L, Wu Y, Fang J, Wei X, Gu Q, El-Hamshary H, Al-Deyab SS, Morsi Y, Mo X Abstract Soft tissue adhesives made from natural hydrogel are attractive in clinical applications due to their excellent properties, such as high water content, good biocompatibility, low immune, good biodegradability. Hydrogels derived from natural polysaccharides and proteins are ideal components for soft tissue adhesive since they resemble the extracellular matrices... περισσότερα »

Low-cost and eco-friendly synthesis of silver nanoparticles using coconut (Cocos nucifera) oil cake extract and its antibacterial activity.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Low-cost and eco-friendly synthesis of silver nanoparticles using coconut (Cocos nucifera) oil cake extract and its antibacterial activity.* Artif Cells Nanomed Biotechnol. 2016 Feb 8;:1-5 Authors: Govarthanan M, Seo YS, Lee KJ, Jung IB, Ju HJ, Kim JS, Cho M, Kamala-Kannan S, Oh BT Abstract The present study reports the simple, inexpensive, eco-friendly synthesis of silver nanoparticles (AgNPs) using coconut oil cake extract. Scanning electron microscopy-energy dispersive spectroscopy peak at 3 keV confirmed the presence of silver. Transmission electron micrograph showed that na...περισσότερα »

Erratum to: Impact of human papillomavirus on head and neck squamous cell cancers in Gabon.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Erratum to: Impact of human papillomavirus on head and neck squamous cell cancers in Gabon.* Infect Agent Cancer. 2016;11:8 Authors: Labouba I, Bertolus C, Koumakpayi HI, Belembaogo E, Miloundja J, Berthet N Abstract [This corrects the article DOI: 10.1186/s13027-015-0036-7.]. PMID: 26855667 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1Q50Xxz via IFTTT

Lysyl oxidase-like 1 polymorphisms in a southwestern Greek cataract population with pseudoexfoliation syndrome.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Lysyl oxidase-like 1 polymorphisms in a southwestern Greek cataract population with pseudoexfoliation syndrome.* Clin Ophthalmol. 2016;10:161-166 Authors: Panoutsopoulos AA, Gartaganis VS, Giannakopoulos MP, Goumas PD, Anastassiou ED, Gartaganis SP Abstract PURPOSE: The aim of this study was to determine the possible association of rs1048661 and rs3825942 single nucleotide polymorphisms (SNPs) in the lysyl oxidase-like 1 (LOXL1) gene of cataract patients from southwestern Greece with pseudoexfoliation (PEX) syndrome. PATIENTS AND METHODS: Ninety-three patients with PEX syndrome a... περισσότερα »

Adenoid cystic carcinoma of head and neck: A single institutional analysis of 66 patients treated with multi-modality approach.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Adenoid cystic carcinoma of head and neck: A single institutional analysis of 66 patients treated with multi-modality approach.* Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):166-171 Authors: Gandhi AK, Roy S, Biswas A, Bhasker S, Sharma A, Thakar A, Mohanti BK Abstract BACKGROUND: Adenoid cystic carcinoma (ACC) accounts for 1% of all head and neck (HN) cancers. MATERIALS AND METHODS: Demographic, clinical, treatment, and survival details of 66 patients were collected (1995-2011) and analyzed. Disease-free survival (DFS) was estimated by Kaplan-Meier method. RESULTS: Primary di... περισσότερα »

Metronomic chemotherapy in platinum-insensitive failures and/or early failures postmultimodality management in oral cancers.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Metronomic chemotherapy in platinum-insensitive failures and/or early failures postmultimodality management in oral cancers.* Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):161-165 Authors: Patil VM, Noronha V, Joshi A, Pinninti R, Dhumal S, Bhattacharjee A, Prabhash K Abstract PURPOSE: Oral cancer patients with platinum-resistant disease and or early failures have limited treatment options. This analysis was planned to study the efficacy of metronomic chemotherapy in this group of patients. MATERIALS AND METHODS: This was a retrospective analysis of oral cancer patients who had...περισσότερα »

Neoadjuvant chemotherapy in oral cancers: Selecting the right patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Neoadjuvant chemotherapy in oral cancers: Selecting the right patients.* Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):148-153 Authors: Vishak S, Rangarajan B, Kekatpure VD Abstract The standard of care treatment for oral squamous cell carcinoma (OSCC) at present, consist of surgical resection followed by adjuvant radiotherapy and chemotherapy as indicated. Despite recent advances the overall prognosis remains guarded. Role of neoadjuvant chemotherapy is being explored with premise of reducing extent of surgical resection, improving loco-regional control and decreasing distant ... περισσότερα »

Indian Council of Medical Research consensus document for the management of tongue cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Indian Council of Medical Research consensus document for the management of tongue cancer.* Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):140-145 Authors: D'Cruz AK, Sharma S, Agarwal JP, Thakar A, Teli A, Arya S, Desai C, Chaturvedi P, Sebastian P, Verghese BT, Kane S, Sucharita V, Kaur T, Shukla DK, Rath GK Abstract The document is based on consensus among the experts and best available evidence pertaining to Indian population and is meant for practice in India.Early diagnosis is imperative in improving outcomes and preserving quality of life. High index of suspicion is to b...περισσότερα »

Commentary on Elective versus therapeutic neck dissection in node-negative oral cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Commentary on Elective versus therapeutic neck dissection in node-negative oral cancer.* Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):137-139 Authors: Kuriakose MA PMID: 26855519 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1K9nNbj via IFTTT

Estimation of Tissue Optical Parameters with Hyperspectral Imaging and Spectral Unmixing.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Estimation of Tissue Optical Parameters with Hyperspectral Imaging and Spectral Unmixing.* Proc SPIE Int Soc Opt Eng. 2015 Mar 17;9417 Authors: Lu G, Qin X, Wang D, Chen ZG, Fei B Abstract Early detection of oral cancer and its curable precursors can improve patient survival and quality of life. Hyperspectral imaging (HSI) holds the potential for noninvasive early detection of oral cancer. The quantification of tissue chromophores by spectral unmixing of hyperspectral images could provide insights for evaluating cancer progression. In this study, non-negative matrix factorizatio... περισσότερα »

Multiportal combined transnasal transoral transpharyngeal endoscopic approach for selected skull base cancers.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Multiportal combined transnasal transoral transpharyngeal endoscopic approach for selected skull base cancers.* Head Neck. 2016 Feb 8; Authors: Turri-Zanoni M, Battaglia P, Dallan I, Locatelli D, Castelnuovo P Abstract BACKGROUND: Minimally invasive endoscopic endonasal approaches to the ventral skull base have evolved considerably over the past several years. However, where there is a lateral extension of tumors as far as the parapharyngeal spaces with inferior extension below the level of the soft palate, limitations remain for an exclusive transnasal approach. METHODS: A combi...περισσότερα »

Dysgenetic polycystic disease of the minor and submandibular salivary glands.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Dysgenetic polycystic disease of the minor and submandibular salivary glands.* Head Neck. 2016 Feb 8; Authors: Koudounarakis E, Willems S, Karakullukcu B Abstract BACKGROUND: Dysgenetic polycystic salivary gland disease is a rare pathology. No case of minor salivary gland involvement has been reported in the literature. METHODS: A female patient presented with bilateral tumors of the parotid glands, bilateral submandibular gland enlargement, and multiple cystic lesions of the oral mucosa. MRI of the neck was performed along with fine-needle aspiration (FNA) of the parotid tumors...περισσότερα »

Experience With the Use of Free Fasciocutaneous Flap in Through-and-Through Cheek-Buccal Defect Reconstruction: Surgical Outcome and Quality of Life Analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Experience With the Use of Free Fasciocutaneous Flap in Through-and-Through Cheek-Buccal Defect Reconstruction: Surgical Outcome and Quality of Life Analysis.* Ann Plast Surg. 2016 Mar;76 Suppl 1:S74-S79 Authors: Lin CH, Chiu YH, Perng CK, Liao WC, Ma H Abstract BACKGROUND: Through-and-through cheek-buccal soft tissue defects usually require fasciocutaneous flaps for reconstruction. However, no ideal flap has been established for reconstruction. METHODS: A retrospective chart review of head and neck reconstruction performed at Taipei Veterans General Hospital between 2003 and 201... περισσότερα »

Modified endoscopic transnasal-transmaxillary-transpterygoid approach to parapharyngeal space tumor resection.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Modified endoscopic transnasal-transmaxillary-transpterygoid approach to parapharyngeal space tumor resection.* Head Neck. 2016 Feb 8; Authors: Wasano K, Yamamoto S, Tomisato S, Kawasaki T, Ogawa K Abstract BACKGROUND: Conventional approaches for removing parapharyngeal space tumors require a cervical skin incision and resection of soft tissues between the skin and parapharyngeal space. The surgical visual field for this conventional approach is limited. METHODS: To decrease invasiveness during removal of benign parapharyngeal space tumors and to enhance the visual field, we devi... περισσότερα »

Intensity-modulated radiotherapy or volumetric-modulated arc therapy in patients with head and neck cancer: Focus on salivary glands dosimetry.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Intensity-modulated radiotherapy or volumetric-modulated arc therapy in patients with head and neck cancer: Focus on salivary glands dosimetry.* Head Neck. 2016 Feb 8; Authors: Vallard A, Guy JB, Mengue Ndong S, Vial N, Rivoirard R, Auberdiac P, Méry B, Langrand-Escure J, Espenel S, Moncharmont C, Ben Mrad M, Diao P, Goyet D, Magné N Abstract BACKGROUND: Despite radiotherapy (RT) technical improvements, high salivary dysfunction rates are still reported in patients with head and neck squamous cell carcinoma (HNSCC). The purpose of the present study was to report salivary glands ... περισσότερα »

Evaluation of the safety and efficacy of carbon ion radiotherapy for locally advanced adenoid cystic carcinoma of the tongue base.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Evaluation of the safety and efficacy of carbon ion radiotherapy for locally advanced adenoid cystic carcinoma of the tongue base.* Head Neck. 2016 Feb 8; Authors: Koto M, Hasegawa A, Takagi R, Ikawa H, Naganawa K, Mizoe JE, Jingu K, Tsujii H, Tsuji H, Kamada T, Okamoto Y, Organizing Committee for the Working Group for Head and Neck Cancer Abstract BACKGROUND: Most cases of adenoid cystic carcinoma (ACC) of the tongue base are radioresistant, and are diagnosed in the advanced stage. Therefore, we evaluated the safety and efficacy of carbon ion radiotherapy (C-ion RT) for locally...περισσότερα »

Superficial siderosis patients with sensorineural hearing loss : Cochlear implantation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
Clinical RecordCochlear implantation is a therapeutic option for superficial siderosis patients with sensorineural hearing lossR Omichia1, S Kariyaa1 c1, Y Maedaa1 and K Nishizakia1 a1 Department of Otolaryngology – Head and Neck Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan Abstract Background: Superficial siderosis is a rare disease that results from chronic bleeding in the subarachnoid space. Haemosiderin deposits throughout the subpial layers of the brain and spinal cord lead to progressive sensorineural hearing loss, which ...περισσότερα »

Aims &amp; Scope/Editorial board

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα
Publication date: April 2016 *Source:*Archives of Oral Biology, Volume 64 from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1RleKFB via IFTTT

Mandibular distraction osteogenesis for the management of upper airway obstruction in children with micrognathia: a systematic review

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα
Publication date: Available online 8 February 2016 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): O. Breik, D. Tivey, K. Umapathysivam, P. Anderson Mandibular distraction osteogenesis (MDO) is increasingly used for neonates and infants with upper airway obstruction secondary to micrognathia. This systematic review was conducted to determine the effectiveness of MDO in the treatment of airway obstruction. The databases searched included PubMed, Embase, Scopus, and grey literature sources. The inclusion criteria were applied to identify studies in children ...περισσότερα »

Pulmonary metastases of head and neck tumours

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Main ArticleSurvival outcomes after surgical resection of pulmonary metastases of head and neck tumoursS Hosokawaa1 c1, K Funaia2, K Sugiyamaa1, G Takahashia1, J Okamuraa1, Y Takizawaa1, T Yamatodania1 and H Minetaa1 a1 Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Japan a2 First Department of Surgery, Hamamatsu University School of Medicine, Japan Abstract Background: There is limited information available regarding the benefits and outcomes of resection of pulmonary metastases arising from head and neck cancers. Methods: A retrospe... περισσότερα »

Behçet's disease : Nasal mucociliary activity

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα
Main ArticleAssessment of nasal mucociliary activity in patients with Behçet's diseaseI Ozbaya1 c1, C Kucura1, F Temİzturka2, Y Ozkana2, C Kahramana3 and F Oghana1 a1 Department of ORL, Dumlupinar University, Kutahya, Turkey a2 Department of Physical Therapy and Rehabilitation, Dumlupinar University, Kutahya, Turkey a3 Department of Internal Medicine, Dumlupinar University, Kutahya, Turkey Abstract Objective: To investigate nasal mucociliary clearance in patients with Behçet's disease. Methods: Thirty patients with Behçet's disease, diagnosed on the basis of criteria defined by the Int... περισσότερα »

Topical intranasal steroids on obstructive adenoids

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα
Main ArticleIs the effect of topical intranasal steroids on obstructive adenoids transient or long-lasting? Case series and systematic review of literatureM A Bitara1a2a3a4 c1, J Nassara1a5 and R Danaa6 a1 Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine and Medical Center, American University of Beirut, Lebanon a2 Department of Pediatrics and Adolescent Medicine, Faculty of Medicine and Medical Center, American University of Beirut, Lebanon a3 Department of ENT Surgery, Children's Hospital at Westmead, Sydney, Australia a4 Pediatric Otolaryngology Program, Al Ja... περισσότερα »

Schwannoma in the retropharyngeal space : Transoral robotic resection

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 54 δευτερόλεπτα
Short CommunicationTransoral robotic resection of a large schwannoma in the retropharyngeal spaceA Gungadeena1 c1, R Lissetera1, J Manickavasagama2 and V Paleria1 a1 Department of Otolaryngology and Head and Neck Surgery, Freeman Hospital, Newcastle upon Tyne, UK a2 Department of Otolaryngology and Head and Neck Surgery, Ninewells Hospital, Dundee, Scotland, UK Abstract Background: External approaches have been traditionally used for the complete excision of large retropharyngeal space lesions. Case report: This paper describes a case of a large schwannoma of the retropharyngeal space... περισσότερα »

Conversion of Head and Neck Cancer Cells Into Radiation-Resistant Cancer Stem Cells Depends on HPV Status … – Newswise (press release)

Newswise (press release) Conversion of Head and Neck Cancer Cells Into Radiation-Resistant Cancer Stem Cells Depends on HPV Status … Newswise (press release) Newswise — Head and neck cancers that test positive for the herpes papilloma virus (HPV) are known to respond more favorably to radiation therapy than those that test HPV-negative, but an explanation […]

Novel study answers age-old questions about how cancers spread by applying tools from evolutionary biology https://t.co/zhswZLgyLy

Novel study answers age-old questions about how cancers spread by applying tools from evolutionary biology https://t.co/zhswZLgyLy from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://twitter.com/ecancer/status/697017134518530048 via IFTTT

miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Simon Raffel, Andreas Trumpp Leukemic stem cells (LSCs) are resistant to conventional chemotherapy and promote acute myeloid leukemia (AML) progression and recurrence. In this issue of Cancer Cell, Lechman and colleagues (2016) identify the microRNA miR-126 as a regulator of PI3K-AKT-mTOR and CDK3 […]

Defining the Molecular Alterations of Ampullary Carcinoma

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Jing Tan, Patrick Tan, Bin Tean Teh Ampullary carcinomas represent a group of heterogeneous tumors that can be histologically divided into two subtypes with distinct pathogenic and clinical characteristics. Yachida et al. (2016) and Gingras et al. (2016) now report the genomic landscape […]

Fall of the Optical Wall: Freedom from the Tyranny of the Microscope Improves Glioma Risk Stratification

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Vijay Ramaswamy, Michael D. Taylor A recent study uses an integrated genomic approach to identify biologically defined subgroups of adult diffuse glioma. These results further lay the foundation for a pathological classification scheme for gliomas that incorporates both histology and molecular biomarkers, which […]

Bringing IDH into the Fold

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Gelareh Zadeh, Kenneth Aldape Glioma-associated mutations in IDH1 or IDH2 lead to aberrant DNA methylation. A recent paper shows that loss of methylation-sensitive CTCF binding in IDH mutant cells leads to disruption of enhancer boundary function, which results in aberrant activation of PDGFRA […]

A Word of Caution on New and Revolutionary Diagnostic Tests

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Eleftherios P. Diamandis from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K9tOEU via IFTTT

TNFα-Mediated Cytotoxic Responses to IAP Inhibition Are Limited by the p38α MAPK Pathway

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Nomeda Girnius, Roger J. Davis Smac mimetics (SMs), a class of drugs that can promote tumor cell death, represent a potential therapeutic strategy for the treatment of cancer. In this issue of Cancer Cell, Lalaoui et al. (2016) report that SM efficacy can […]

a Word of Caution on New and Revolutionary Diagnostic Tests

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Myron G. Best, Nik Sol, Bakhos A. Tannous, Pieter Wesseling, Thomas Wurdinger from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K9tPsg via IFTTT

Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics

Publication date: 8 February 2016 Source:Cancer Cell, Volume 29, Issue 2 Author(s): Najoua Lalaoui, Kay Hänggi, Gabriela Brumatti, Diep Chau, Nhu-Y.N. Nguyen, Lazaros Vasilikos, Lisanne M. Spilgies, Denise A. Heckmann, Chunyan Ma, Margherita Ghisi, Jessica M. Salmon, Geoffrey M. Matthews, Elisha de Valle, Donia M. Moujalled, Manoj B. Menon, Sukhdeep Kaur Spall, Stefan P. Glaser, […]

Suture materials in the nasal cavity

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Main ArticleThe effects of different suture materials in the nasal cavity A Durmaza1 c1, A Kilica2, R Gumrala2, U Yildizoglua1 and B Polata1 a1 Department of Otolaryngology, Gülhane Military Medical Academy, Ankara, Turkey a2 Department of Medical Microbiology, Gülhane Military Medical Academy, Ankara, Turkey Abstract Objective: To investigate the effects of different suture materials in the nasal cavity on encrustation and micro-organism colonisation. Methods: Four different suture materials were used to suture the nasal septum. The effects of suture materials on intranasal encrustatio...περισσότερα »

Liquid Thyroxine Ingested at Breakfast

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
•A Double-Blind Placebo-Controlled Trial of Liquid Thyroxine Ingested at Breakfast: Results of the TICO Study Thyroid February 2016, Vol. 26, No. 2, 197-202 Posted online on February 8, 2016. (doi:10.1089/thy.2015.0422) View Table of Contents | [image: RSS] TOC, Citation What is RSS? | Email Alert Author information Carlo Cappelli,1 Ilenia Pirola,1 Linda Daffini,1 Annamaria Formenti,1 Carmelo Iacobello,2 Alessandra Cristiano,1 Elena Gandossi,1 Enrico Agabiti Rosei,1 and Maurizio Castellano1 1Department of Medical and Surgical Sciences, Endocrine and Metabolic Unit, University of Br... περισσότερα »

Convection enhanced delivery of chemotherapy to paediatric brain stem tumours

Prof Gill talks to ecancertv at Children with Cancer UK’s workshop on Drug Delivery in Paediatric Brain Tumours in London, UK. In the interview he discusses early clinical experience of intermittently delivering carboplatin directly to paediatric… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1TPPZSC via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; […]

Intra-arterial chemotherapy methods for CNS tumours

Dr Pearl talks to ecancertv at Children with Cancer UK’s workshop on Drug Delivery in Paediatric Brain Tumours in London, UK. In the interview she discusses her work on intra-arterial chemotherapy for central nervous system tumours. Dr Pearl explains… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/20lNJCs via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete […]

Treating relapsed brain tumours with anti-angiogenic metronomic therapy

Dr Slavc talks to ecancertv at Children with Cancer UK’s workshop on Drug Delivery in Paediatric Brain Tumours in London, UK. In the interview she discusses the use of metronomic anti-angiogenic therapy in patients with relapsed brain… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1TPQ0Wt via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 […]

The “net” of the Internet: Risk Factors for Cyberbullying among Secondary-School Students in Greece

Abstract Cyberbullying is one of the most common threats an adolescent might face online with serious negative consequences at the social, emotional and educational level. Despite the intense study of the phenomenon over the past decade, most researchers ask for new directions in research that will focus on risk and protective factors. This study attempted […]

Higher Fines—Fewer Traffic Offences? A Multi-Site Observational Study

Abstract Assess the impact of a 100-per cent increase of fines on compliance with speed-limits (50 km/h) and parking regulations in urban areas. Norm violations were measured through standardized observations in all five major cities in Switzerland before and after fines had been raised by 100 % or more at two pre- and two post-intervention […]

Hereditary Angioedema Definition, Symptoms &amp; Treatment: BioCryst’s Genetic Disorder Drug Fails Phase 2 – Latinos Health

Latinos Health Hereditary Angioedema Definition, Symptoms &amp; Treatment: BioCryst’s Genetic Disorder Drug Fails Phase 2 Latinos Health These plates allow scientists to look at lots of cells at the same time and directly compare cells that have or have not been treated with a drug, at the Cancer Research UK Cambridge Institute on December 9, […]

EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM

EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM Oulhote Y1, Chevrier J1, Bouchard MF Exposure to Polybrominated Diphenyl Ethers (PBDEs) and Hypothyroidism in Canadian Women. J Clin Endocrinol Metab. 2016 Feb;101(2):590-8. doi: 10.1210/jc.2015-2659. Epub 2015 Nov 25. Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in a wide range of products, resulting in widespread […]

The Role of Maternal Cardiac Vagal Control in the Association between Depressive Symptoms and Gestational Hypertension

Publication date: Available online 8 February 2016 Source:Biological Psychology Author(s): Codie R. Rouleau, Lianne M. Tomfohr-Madsen, Tavis S. Campbell, Nicole Letourneau, Maeve O’Beirne, Gerald F. Giesbrecht Reduced cardiac vagal control, indexed by relatively lower high-frequency heart rate variability (HF-HRV), is implicated in depressed mood and hypertensive disorders among non-pregnant adults whereas research in pregnancy is […]

Scientists discover a unique mechanism for a high-risk leukaemia https://t.co/PmmbVdCUnL

Scientists discover a unique mechanism for a high-risk leukaemia https://t.co/PmmbVdCUnL from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/697002038308302848 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Society Page

Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1QSB2MP via IFTTT

Iodine Deficiency Disorders

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα
•Ensuring Effective Prevention of Thyroid February 2016, Vol. 26, No. 2, 189-196 Posted online on February 8, 2016. (doi:10.1089/thy.2015.0543) View Table of Contents | [image: RSS] TOC, Citation What is RSS? | Email Alert Author information Henry Völzke,1 Philippe Caron,2 Lisbeth Dahl,3 João J. de Castro,4 Iris Erlund,5 Simona Gaberšček,6Ingibjörg Gunnarsdottir,7 Alicja Hubalewska-Dydejczyk,8 Till Ittermann,1 Ludmila Ivanova,9 Borislav Karanfilski,10 Rehman M. Khattak,1 Zvonko Kusić,11 Peter Laurberg,12 John H. Lazarus,13 Kostas B. Markou,14 Rodrigo Moreno-Reyes,15 Endre V. Nagy,16... περισσότερα »

Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 59 δευτερόλεπτα
: Pooled Analysis of 22 Prospective Studies *To cite this article:* Kitahara Cari M., McCullough Marjorie L., Franceschi Silvia, Rinaldi Sabina, Wolk Alicja, Neta Gila, Olov Adami Hans, Anderson Kristin, Andreotti Gabriella, Beane Freeman Laura E., Bernstein Leslie, Buring Julie E., Clavel-Chapelon Francoise, De Roo Lisa A., Gao Yu-Tang, Gaziano J. Michael, Giles Graham G., Håkansson Niclas, Horn-Ross Pamela L., Kirsh Vicki A., Linet Martha S., MacInnis Robert J., Orsini Nicola, Park Yikyung, Patel Alpa V., Purdue Mark P., Riboli Elio, Robien Kimberly, Rohan Thomas, Sandler Dale P., ...περισσότερα »

Pediatric Differentiated Thyroid Carcinoma of Follicular Cell Origin

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
: Prognostic Significance of Histologic Subtypes: Thyroid Feb 2016, Vol. 26, No. 2: 219-226. Author information Sadana Balachandar,1 Michael La Quaglia,2 R. Michael Tuttle,3 Glenn Heller,4 Ronald A. Ghossein,5 andCharles A. Sklar6,7 1Department of Pediatrics, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey. 2Department of Pediatric Surgery, Memorial Sloan Kettering Cancer Center, New York, New York. 3Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. 4Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer C... περισσότερα »

Pediatric Differentiated Thyroid Carcinoma of Follicular Cell Origin: Prognostic Significance of Histologic Subtypes

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Pediatric Differentiated Thyroid Carcinoma of Follicular Cell Origin: Prognostic Significance of Histologic Subtypes: Thyroid Feb 2016, Vol. 26, No. 2: 219-226. Author information Sadana Balachandar,1 Michael La Quaglia,2 R. Michael Tuttle,3 Glenn Heller,4 Ronald A. Ghossein,5 andCharles A. Sklar6,7 1Department of Pediatrics, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey. 2Department of Pediatric Surgery, Memorial Sloan Kettering Cancer Center, New York, New York. 3Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. 4Departme... περισσότερα »

EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM: EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM *Oulhote Y1, Chevrier J1, Bouchard MF Exposure to Polybrominated Diphenyl Ethers (PBDEs) and Hypothyroidism in Canadian Women.* J Clin Endocrinol Metab. 2016 Feb;101(2):590-8. doi: 10.1210/jc.2015-2659. Epub 2015 Nov 25. Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in a wide range of products, resulting in widespread human exposure. Epidemiological studies in some populations reported exposure to PBDEs and thyr... περισσότερα »

Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in a wide range of products, resulting in widespread human exposure

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM: EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM *Oulhote Y1, Chevrier J1, Bouchard MF Exposure to Polybrominated Diphenyl Ethers (PBDEs) and Hypothyroidism in Canadian Women.* J Clin Endocrinol Metab. 2016 Feb;101(2):590-8. doi: 10.1210/jc.2015-2659. Epub 2015 Nov 25. Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in a wide range of products, resulting in widespread human exposure. Epidemiological studies in some populations reported exposure to PBDEs and thyr... περισσότερα »

Eosinophilic esophagitis histology scoring system and evidence

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring: Summary Eosinophilic esophagitis (EoE) is diagnosed by symptoms, and at least 15 intraepithelial eosinophils per high power field in an esophageal biopsy. Other pathologic features have not been emphasized. We developed a histology scoring system for esophageal biopsies that evaluates eight features: eosinophil density, basal zone hyperplasia, eosinophil abscesses, eosinophil surface layering, dilated intercellu...περισσότερα »

Prophylactic efficacy of 3- or 5-cm pancreatic stents for preventing post-ERCP pancreatitis: A prospective, randomized trial

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 1 ώρα
Journal of Clinical Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1TPHqr1 Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Improved left liver-up congenital diaphragmatic hernia survival by early repair before extracorporeal membrane oxygenation: optimization of patient selection by multivariate risk modeling

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 1 ώρα
Journal of the American College of Surgeons from #Medicine via ola Kala on Inoreader http://ift.tt/1QSweqN Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Cerebral sparganosis in children: epidemiologic and radiologic characteristics and treatment outcomes: a report of 9 cases.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Cerebral sparganosis in children: epidemiologic and radiologic characteristics and treatment outcomes: a report of 9 cases.* World Neurosurg. 2016 Feb 5; Authors: JueShen YY, Yuan Z, FengGao ZX, Jiang L, Jiang K Abstract Pediatric cerebral sparganosis has been seldom reported. In the current study, we retrospectively reviewed the clinicopathologic records of 9 consecutive pediatric cases of cerebral sparganosis and analyzed their epidemiologic characteristics and clinical outcomes. Our cases included 6 boys and 3 girls, all from rural areas, and their median age at diagnosis was...περισσότερα »

Defensive Medicine: A Game Where Perception Trumps Reality.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Defensive Medicine: A Game Where Perception Trumps Reality.* World Neurosurg. 2016 Feb 5; Authors: Bean JR PMID: 26855308 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1T2XtB2 via IFTTT

Prognostic Value of FET-PET Imaging for Histopathological Characteristics and Progression Free Survival in Low Grade Glioma Patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Prognostic Value of FET-PET Imaging for Histopathological Characteristics and Progression Free Survival in Low Grade Glioma Patients.* World Neurosurg. 2016 Feb 5; Authors: Bette S, Gempt J, Delbridge C, Kirschke JS, Schlegel J, Foerster S, Huber T, Pyka T, Zimmer C, Meyer B, Ringel F PMID: 26855307 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1WafvRd via IFTTT

Is Patient Age Associated with Perioperative Outcomes Following Surgical Resection of Benign Cranial Nerve Neoplasms?

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Is Patient Age Associated with Perioperative Outcomes Following Surgical Resection of Benign Cranial Nerve Neoplasms?* World Neurosurg. 2016 Feb 5; Authors: McCutcheon BA, Grauberger J, Murphy M, Kerezoudis P, Rinaldo L, Shepherd D, Maloney P, Snyder K, Carter BS, Bydon M, Van Gompel JJ, Link MJ, Mayo Clinic Neuro-Informatics Laboratory Abstract OBJECTIVE: Prior literature has demonstrated that increasing age is associated with decreased rates of operative management and gross total resection in patients with vestibular schwannomas. METHODS: The ACS-NSQIP data registry was used f... περισσότερα »

Elderly Patients with Severe Traumatic Brain Injury Could Benefit from Surgical Treatment.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Elderly Patients with Severe Traumatic Brain Injury Could Benefit from Surgical Treatment.* World Neurosurg. 2016 Feb 5; Authors: Wan X, Liu S, Wang S, Zhang S, Yang H, Ou Y, Zhao M, James L, Shu K, Chen J, Lei T Abstract BACKGROUND: Whether aggressive or conservative managements should be used for the elderly patients with severe traumatic brain injury (TBI) remains controversial. This study aimed to assess the outcome of surgical alternatives for treatment of the severe traumatic intracranial hematoma (TIH) in patients aged 65 years or older and identify the factors that may ... περισσότερα »

Long term results and efficacy of laminectomy with fusion vs. Young laminoplasty for the treatment of degenerative spinal stenosis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Long term results and efficacy of laminectomy with fusion vs. Young laminoplasty for the treatment of degenerative spinal stenosis.* World Neurosurg. 2016 Feb 4; Authors: Škoro I, Stančić M, Kovačević M, Đurić KS PMID: 26852714 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1T2XvJ8 via IFTTT

Craniectomy Versus Craniotomy for Posterior Fossa Metastases, Complication Profile.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Craniectomy Versus Craniotomy for Posterior Fossa Metastases, Complication Profile.* World Neurosurg. 2016 Feb 4; Authors: Hadanny A, Rozovski U, Nossek E, Shapira Y, Strauss I, Kanner AA, Sitt R, Ram Z, Shahar T Abstract BACKGROUND: Surgery for resection of posterior fossa metastases (PFM) may include suboccipital craniotomy or craniectomy. The optimal surgical technique is yet to be defined. OBJECTIVE: In this study, we examined the association between the chosen surgical approach and the occurrence of postoperative complications. METHODS: We retrospectively evaluated medical r... περισσότερα »

Hemodynamic Effect of Flow Diverter and Coils in the Treatment of Large and Giant Intracranial Aneurysms.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Hemodynamic Effect of Flow Diverter and Coils in the Treatment of Large and Giant Intracranial Aneurysms.* World Neurosurg. 2016 Feb 4; Authors: Jing L, Zhong J, Liu J, Yang X, Paliwal N, Meng H, Wang S, Zhang Y Abstract BACKGROUND: This study aimed to investigate the hemodynamic changes induced by the flow diverter (FD) and coils in treatment of internal carotid artery aneurysms, and to evaluate the effect of this treatment by using angiographic follow-up data. METHODS: Six large and giant aneurysms were treated by the Tubridge FD and loose packing coils between June 2013 and Ma... περισσότερα »

The “net” of the Internet: Risk Factors for Cyberbullying among Secondary-School Students in Greece

Abstract Cyberbullying is one of the most common threats an adolescent might face online with serious negative consequences at the social, emotional and educational level. Despite the intense study of the phenomenon over the past decade, most researchers ask for new directions in research that will focus on risk and protective factors. This study attempted […]

Higher Fines—Fewer Traffic Offences? A Multi-Site Observational Study

Abstract Assess the impact of a 100-per cent increase of fines on compliance with speed-limits (50 km/h) and parking regulations in urban areas. Norm violations were measured through standardized observations in all five major cities in Switzerland before and after fines had been raised by 100 % or more at two pre- and two post-intervention […]

To the Editor

Publication date: Available online 8 February 2016 Source:Clinical Therapeutics Author(s): Xiulu Ruan from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mphxR8 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1nZU4rs via IFTTT

Pharmacokinetic and Pharmacodynamic Effects of Multiple-Dose Administration of Omarigliptin, a Once-Weekly Dipeptidyl Peptidase-4 Inhibitor, in Obese Participants With and Without Type 2 Diabetes Mellitus

Publication date: Available online 9 February 2016 Source:Clinical Therapeutics Author(s): Carol Addy, Daniel Tatosian, Xiaoli S. Glasgow, Isaias N. Gendrano, Eunkyung Kauh, Ashley Martucci, Amy O. Johnson-Levonas, RN Diana Selverian, Catherine Z. Matthews, Marie Gutierrez, John A. Wagner, S. Aubrey Stoch PurposeOmarigliptin (MK-3102) is a potent, oral, long-acting dipeptidyl peptidase (DPP)-4 inhibitor approved in Japan […]

Improvement of Pediatric Drug Development: Regulatory and Practical Frameworks

Publication date: Available online 8 February 2016 Source:Clinical Therapeutics Author(s): Katusra Tsukamoto, Kelly A. Carroll, Taku Onishi, Naoki Matsumaru, Daniel Brasseur, Hidefumi Nakamura PurposeA dearth in pediatric drug development often leaves pediatricians with no alternative but to prescribe unlicensed or off-label drugs with a resultant increased risk of adverse events. We present the current status […]

Vorwort von Prof. Dr. Hans-Christoph Steinhausen

from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Q500Fs via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1QoYqP9 via IFTTT

Hereditary Angioedema Definition, Symptoms &amp; Treatment: BioCryst’s Genetic Disorder Drug Fails Phase 2 – Latinos Health

Latinos Health Hereditary Angioedema Definition, Symptoms &amp; Treatment: BioCryst’s Genetic Disorder Drug Fails Phase 2 Latinos Health These plates allow scientists to look at lots of cells at the same time and directly compare cells that have or have not been treated with a drug, at the Cancer Research UK Cambridge Institute on December 9, […]

The Role of Maternal Cardiac Vagal Control in the Association between Depressive Symptoms and Gestational Hypertension

Publication date: Available online 8 February 2016 Source:Biological Psychology Author(s): Codie R. Rouleau, Lianne M. Tomfohr-Madsen, Tavis S. Campbell, Nicole Letourneau, Maeve O’Beirne, Gerald F. Giesbrecht Reduced cardiac vagal control, indexed by relatively lower high-frequency heart rate variability (HF-HRV), is implicated in depressed mood and hypertensive disorders among non-pregnant adults whereas research in pregnancy is […]

EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM

EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM Oulhote Y1, Chevrier J1, Bouchard MF Exposure to Polybrominated Diphenyl Ethers (PBDEs) and Hypothyroidism in Canadian Women. J Clin Endocrinol Metab. 2016 Feb;101(2):590-8. doi: 10.1210/jc.2015-2659. Epub 2015 Nov 25. Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in a wide range of products, resulting in widespread […]

An unusual case of dysphagia in a child.

Related Articles An unusual case of dysphagia in a child. Dysphagia. 2014 Aug;29(4):527-9 Authors: Demirhan E, Kozen MA, Ciyiltepe M PMID: 25082274 [PubMed – indexed for MEDLINE] from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1Sdrqzo via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1nZRxO2 via IFTTT

Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-β1a and Circulating Proinflammatory Cytokines in Relapsing–Remitting Multiple Sclerosis

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
Abstract Palmitoylethanolamide (PEA) is an endogenous lipid mediator known to reduce pain and inflammation. However, only limited clinical studies have evaluated the effects of PEA in neuroinflammatory and neurodegenerative diseases. Multiple sclerosis (MS) is a chronic autoimmune and inflammatory disease of the central nervous system. Although subcutaneous administration of interferon (IFN)-β1a is approved as first-line therapy for the treatment of relapsing–remitting MS (RR-MS), its commonly reported adverse events (AEs) such as pain, myalgia, and erythema at the injection site, ...περισσότερα »

Contents

[image: alertIcon.gif] Publication date: March 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1QSB4Ew via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Spindle cell variant of ameloblastic carcinoma: a case report and literature review

Publication date: March 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 Author(s): Yuki Matsushita, Shuichi Fujita, Souichi Yanamoto, Shin-ichi Yamada, Satoshi Rokutanda, Kentaro Yamashita, Tohru Ikeda, Masahiro Umeda Spindle cell variant of ameloblastic carcinoma is an extremely rare tumor. Severe dedifferentiated spindle cell variants are diagnostically challenging, particularly in small biopsy specimens. Here, we report a case of spindle cell variant of ameloblastic carcinoma in the mandible of a 69-year-old male patient and revie... περισσότερα »

Basal cell adenoma with S-100 positive stroma: a case report and literature review

[image: alertIcon.gif] Publication date: March 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 Author(s): Emanuela Ortolani, Antonella Polimeni, Libero Lauriola, Antonella Coli Basal cell adenoma (BCA) of the salivary gland with presence of abundant S-100–positive stromal cells has been rarely reported. A case occurring in a 75-year-old man is presented here, as well as a review of the literature on the subject. The patient presented with a nodule in the right parotid gland. In addition to the typical features of BCA, histologically ... περισσότερα »

To the Editor

Publication date: Available online 8 February 2016 Source:Clinical Therapeutics Author(s): Xiulu Ruan from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mphxR8 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Improvement of Pediatric Drug Development: Regulatory and Practical Frameworks

Publication date: Available online 8 February 2016 Source:Clinical Therapeutics Author(s): Katusra Tsukamoto, Kelly A. Carroll, Taku Onishi, Naoki Matsumaru, Daniel Brasseur, Hidefumi Nakamura PurposeA dearth in pediatric drug development often leaves pediatricians with no alternative but to prescribe unlicensed or off-label drugs with a resultant increased risk of adverse events. We present the current status […]

Pharmacokinetic and Pharmacodynamic Effects of Multiple-Dose Administration of Omarigliptin, a Once-Weekly Dipeptidyl Peptidase-4 Inhibitor, in Obese Participants With and Without Type 2 Diabetes Mellitus

Publication date: Available online 9 February 2016 Source:Clinical Therapeutics Author(s): Carol Addy, Daniel Tatosian, Xiaoli S. Glasgow, Isaias N. Gendrano, Eunkyung Kauh, Ashley Martucci, Amy O. Johnson-Levonas, RN Diana Selverian, Catherine Z. Matthews, Marie Gutierrez, John A. Wagner, S. Aubrey Stoch PurposeOmarigliptin (MK-3102) is a potent, oral, long-acting dipeptidyl peptidase (DPP)-4 inhibitor approved in Japan […]

Vorwort von Prof. Dr. Hans-Christoph Steinhausen

from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Q500Fs via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Oral Lesions : Foliate papillae. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Lymphoid aggregates . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Varix (plural: varices) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Torus palatinus and torus mandibularis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Idiopathic osteosclerosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Osteoporotic bone marrow defect . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Fordyce granules . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Leukoedema . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Aphthous stomatitis (Canker sores, recurrent aphthous stomatitis, RAS) . . . . . . . . 11 Herpes simplex virus infections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Denture sore mouth (DSM) and Papillary hyperplasia (PH). . . . . . . . . . . . . . . . . . 13 Epulis fissuratum (Inflammatory fibrous hyperplasia). . . . . . . . . . . . . . . . . . . . . . 14 Irritation fibroma (traumatic fibroma). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Mucocele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Papilloma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Peripheral ossifying fibroma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Pyogenic granuloma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Peripheral giant cell granuloma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Traumatic ulcer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Nicotine stomatitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Drug-induced gingival hyperplasia (Dilantin hyperplasia) . . . . . . . . . . . . . . . . . . . 23 Geographic tongue (benign migratory glossitis, erythema migrans). . . . . . . . . . . . 24 Lichen planus. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Angular cheilosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 Candidiasis (Moniliasis, Thrush) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Pulpitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Dental caries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Plaque induced gingivitis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 Necrotizing ulcerative gingivitis (Vincent’s infection, trench mouth). . . . . . . . . . . . 31 Periodontitis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Periapical cyst (radicular cyst) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 Periapical dental granuloma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 Condensing osteitis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 Periocoronitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 Amalgam tattoo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 Hairy tongue (coated tongue) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 Nasopalatine duct cyst . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Dentigerous cyst . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 Leukoplakia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Erythroplasia (erythroplakia) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 Squamous cell carcinoma (epidermoid carcinoma). . . . . . . . . . . . . . . . . . . . . . . . 43 Snuff lesion (smokeless tobacco lesion) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 Cementoma (periapical cemental dysplasia) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Acquired immune deficiency syndrome (AIDS) . . . . . . . . . . . . . . . . . . . . . . . . . . 46

Αλέξανδρος ΣφακιανάκηςστοOtolaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 1 ώρα
*Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.* Int J Audiol. 2016 Feb 6;:1-6 Authors: English R, Plant K, Maciejczyk M, Cowan R Abstract OBJECTIVE: For a group of cochlear implant recipients, who use hearing aids in the contralateral ear, the benefit of NAL-NL2 relative to a recipients' own prescription was assessed. Whether there was a preferred frequency response and/or gain deviation from NAL-NL2 was then investigated. DESIGN: Speech recognition and self-reported ratings of benefi...περισσότερα »

An unusual case of dysphagia in a child.

Related Articles An unusual case of dysphagia in a child. Dysphagia. 2014 Aug;29(4):527-9 Authors: Demirhan E, Kozen MA, Ciyiltepe M PMID: 25082274 [PubMed – indexed for MEDLINE] from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1Sdrqzo via IFTTT

The relationship between limit of Dysphagia and average volume per swallow in patients with Parkinson’s disease.

Related Articles The relationship between limit of Dysphagia and average volume per swallow in patients with Parkinson’s disease. Dysphagia. 2014 Aug;29(4):419-24 Authors: Belo LR, Gomes NA, Coriolano Md, de Souza ES, Moura DA, Asano AG, Lins OG Abstract The goal of this study was to obtain the limit of dysphagia and the average volume per […]

Esophageal peristaltic defects in adults with functional dysphagia.

Related Articles Esophageal peristaltic defects in adults with functional dysphagia. Dysphagia. 2014 Aug;29(4):519-26 Authors: Ratuapli SK, Hansel SL, Umar SB, Burdick GE, Ramirez FC, Fleischer DE, Harris LA, Lacy BE, DiBaise JK, Crowell MD Abstract Functional dysphagia (FD) is characterized by the presence of dysphagia without evidence of mechanical esophageal obstruction, GERD, and histopathology-based esophageal […]

Tongue pressure during swallowing in adults with down syndrome and its relationship with palatal morphology.

Related Articles Tongue pressure during swallowing in adults with down syndrome and its relationship with palatal morphology. Dysphagia. 2014 Aug;29(4):509-18 Authors: Hashimoto M, Igari K, Hanawa S, Ito A, Takahashi A, Ishida N, Koyama S, Ono T, Sasaki K Abstract In individuals with Down syndrome, hypotonicity of the tongue and an underdeveloped maxilla may lead […]

Carers’ experiences of dysphagia in people treated for head and neck cancer: a qualitative study.

Related Articles Carers’ experiences of dysphagia in people treated for head and neck cancer: a qualitative study. Dysphagia. 2014 Aug;29(4):450-8 Authors: Nund RL, Ward EC, Scarinci NA, Cartmill B, Kuipers P, Porceddu SV Abstract The implication of dysphagia for people treated nonsurgically for head and neck cancer (HNC) and its detrimental effects on functioning and […]

Viscosity differences between thickened beverages suitable for elderly patients with dysphagia.

Related Articles Viscosity differences between thickened beverages suitable for elderly patients with dysphagia. Dysphagia. 2014 Aug;29(4):483-8 Authors: Garin N, De Pourcq JT, Martín-Venegas R, Cardona D, Gich I, Mangues MA Abstract Dysphagia has been associated with a high risk of undernutrition and aspiration pneumonia in the elderly. It is commonly managed by adding commercial thickening […]

Acoustic study of pharyngeal swallowing as a function of the volume and consistency of the bolus.

Related Articles Acoustic study of pharyngeal swallowing as a function of the volume and consistency of the bolus. Dysphagia. 2014 Aug;29(4):468-74 Authors: Hammoudi K, Boiron M, Hernandez N, Bobillier C, Morinière S Abstract Cervical auscultation is a noninvasive technique for the exploration of swallowing and has been used since the 1960s. The aim of our […]

Differences in videofluoroscopic swallowing study (VFSS) findings according to the vascular territory involved in stroke.

Related Articles Differences in videofluoroscopic swallowing study (VFSS) findings according to the vascular territory involved in stroke. Dysphagia. 2014 Aug;29(4):444-9 Authors: Kim SY, Kim TU, Hyun JK, Lee SJ Abstract Dysphagia affects up to half of stroke patients and increases the risk of pneumonia and fatal outcomes. In order to assess swallowing difficulty, videofluoroscopic swallowing […]

Implications of changing the amount of thickener in thickened infant formula for infants with dysphagia.

Related Articles Implications of changing the amount of thickener in thickened infant formula for infants with dysphagia. Dysphagia. 2014 Aug;29(4):432-7 Authors: September C, Nicholson TM, Cichero JA Abstract When a dysphagic infant is prescribed thickened infant formula (TIF) as a treatment method, some clinicians determine their own addition rates of thickener to meet the specific […]

Esophageal stents for the treatment of malignant dysphagia in patients with esophageal cancer.

Related Articles Esophageal stents for the treatment of malignant dysphagia in patients with esophageal cancer. Hosp Pract (1995). 2010;38(3):94-102 Authors: Brimhall B, Adler DG Abstract Self-expanding metal stents (SEMS) are the current standard for relief of malignant esophageal dysphagia. Self-expanding plastic stents (SEPS) are also used for relief of malignant esophageal dysphagia and as neoadjuvant […]

The Role of Maternal Cardiac Vagal Control in the Association between Depressive Symptoms and Gestational Hypertension

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: S03010511.gif] Publication date: Available online 8 February 2016 *Source:*Biological Psychology Author(s): Codie R. Rouleau, Lianne M. Tomfohr-Madsen, Tavis S. Campbell, Nicole Letourneau, Maeve O'Beirne, Gerald F. Giesbrecht Reduced cardiac vagal control, indexed by relatively lower high-frequency heart rate variability (HF-HRV), is implicated in depressed mood and hypertensive disorders among non-pregnant adults whereas research in pregnancy is limited. This study examined whether maternal HF-HRV during pregnancy mediates the association between depressed mood and gestatio... περισσότερα »

Antibiotic Reservoir Injection Reduces Shunt Infection in Adults.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Antibiotic Reservoir Injection Reduces Shunt Infection in Adults.* World Neurosurg. 2016 Feb 4; Authors: Burrows AM, Murphy ME, Daniels DJ, Meyer FB PMID: 26852711 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1WafuN0 via IFTTT

Neurosurgery and Telemedicine in the United States of America: Assessment of the Risks and Opportunities.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Neurosurgery and Telemedicine in the United States of America: Assessment of the Risks and Opportunities.* World Neurosurg. 2016 Feb 4; Authors: Kahn EN, La Marca F, Mazzola CA PMID: 26852710 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1PLJ4YM via IFTTT

Intramedullary recurrence of a thoracic meningioma - Presentation of an unusual case and review of the literature.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Intramedullary recurrence of a thoracic meningioma - Presentation of an unusual case and review of the literature.* World Neurosurg. 2016 Feb 4; Authors: Piazza M, Ramayya A, Geiger G, Alonso-Basanta M, Nasrallah MP, Welch W, Ozturk A Abstract BACKGROUND AND IMPORTANCE: Spinal meningiomas are typically extra-axial, slow-growing, benign tumors that arise from the arachnoid cap cells. Intramedullary spinal meningiomas are exceedingly rare with few cases reported in the literature. CLINICAL PRESENTATION: 64 year-old man with a history of Grade I thoracic meningioma at the T4 level ...περισσότερα »

Extensive therapies for extraneural metastases from glioblastoma, as confirmed with the OncoScan assay.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Extensive therapies for extraneural metastases from glioblastoma, as confirmed with the OncoScan assay.* World Neurosurg. 2016 Feb 4; Authors: Xu M, Wang Y, Xu J, Yao Y, Yu WX, Zhong P Abstract BACKGROUND: Extraneural metastasis from glioblastoma is usually diagnosed according to the histopathology and immunohistochemical staining of a tumor specimen. However, information regarding the molecular features of glioblastoma and optimal treatment strategies for extraneural metastasis is limited. CASE DESCRIPTION: A 58-year-old woman with a glioblastoma located in the left temporal lo... περισσότερα »

Neoadjuvant chemotherapy in technically unresectable carcinoma of external auditory canal.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Neoadjuvant chemotherapy in technically unresectable carcinoma of external auditory canal.* Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):172-175 Authors: Joshi A, Tandon N, Noronha V, Dhumal S, Patil V, Arya S, Juvekar S, Agarwal J, DCruz A, Pai P, Prabhash K Abstract BACKGROUND: Carcinoma of external auditory canal (EAC) is a very rare malignancy with surgical resection as the main modality of treatment. The outcomes with nonsurgical modalities are very dismal. We present a retrospective analysis of 4 patients evaluating the role of neoadjuvant chemotherapy in technically un... περισσότερα »

Pediatric Differentiated Thyroid Carcinoma of Follicular Cell Origin: Prognostic Significance of Histologic Subtypes.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Pediatric Differentiated Thyroid Carcinoma of Follicular Cell Origin: Prognostic Significance of Histologic Subtypes.* Thyroid. 2016 Feb;26(2):219-226 Authors: Balachandar S, La Quaglia M, Tuttle RM, Heller G, Ghossein RA, Sklar CA Abstract BACKGROUND: Thyroid cancers are rare in the pediatric age group, and unlike in adults, few data are available regarding the clinical implication of histologic subtypes in the pediatric population. The purpose of the current study was to determine the prognostic significance of histologic subtypes of differentiated thyroid cancer (DTC) in a la... περισσότερα »

A Rare Nasopharyngeal Teratoma Arising From the Vomer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*A Rare Nasopharyngeal Teratoma Arising From the Vomer.* J Craniofac Surg. 2016 Feb 5; Authors: Pang X, Kwon HJ, Shi B, Li C Abstract Teratomas are rare germ cell neoplasms derived from the 3 germinal layers (ectoderm, mesoderm, and endoderm). Nasopharyngeal teratoma is a very rare teratoma arising anywhere from the oronasal cavity, regarded as an expanding, avity filling lesion, with a high mortality rate because of severe airway obstruction, especially in the neonatal period and make up only 2% of all teratomas. The authors present a case of an infant girl with a single, finger...περισσότερα »

NEUROFIBROMATOSIS AS A GATEWAY TO BETTER TREATMENT FOR A VARIETY OF MALIGNANCIES.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*NEUROFIBROMATOSIS AS A GATEWAY TO BETTER TREATMENT FOR A VARIETY OF MALIGNANCIES.* Prog Neurobiol. 2016 Feb 4; Authors: Bakker AC, La Rosa S, Sherman LS, Knight P, Lee H, Pancza P, Nievo M Abstract NF is a group of rare genetic disorders that can affect all races equally at an incidence from 1:3000 (NF1) to a log unit lower for NF2 and Schwannomatosis. Since the research community is reporting an increasing number of malignant cancers that carry mutations in the NF genes, the general interest of both the research and pharma community is increasing and the authors saw an opportu... περισσότερα »

Chondromyxoid fibroma of the pubic ramus: a case report and literature review.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Chondromyxoid fibroma of the pubic ramus: a case report and literature review.* Acta Orthop Traumatol Turc. 2016;50(1):115-9 Authors: Arıkan M, Toğral G, Yıldırım A, Aktaş E Abstract Chondromyxoid fibromas (CMF) are benign cartilaginous bone tumors which are found most frequently in the metaphyses of long bones. They comprise less than 1% of primary bone neoplasms. We report an interesting incidental case of a 43-year-old woman with a CMF of the left pubic ramus, presenting with complaints of gradual onset of left groin pain over a period of 2 years. According to radiological ex...περισσότερα »

Squamous cell carcinoma of the anal canal treated with chemoradiotherapy in a patient with HIV.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Squamous cell carcinoma of the anal canal treated with chemoradiotherapy in a patient with HIV.* Nihon Shokakibyo Gakkai Zasshi. 2016;113(2):254-62 Authors: Sugimoto A, Nakazuru S, Sakakibara Y, Nishio K, Yamada T, Ishida H, Yajima K, Uehira T, Mori K, Mita E Abstract Since the introduction of combination antiretroviral therapy (ART), the life expectancy has increased for patients infected with human immunodeficiency virus (HIV). This has been associated with reductions in the incidences of some AIDS-defining malignancies, such as Kaposi sarcoma and non-Hodgkin lymphoma, but has...περισσότερα »

Unresectable Middle Mediastinal Biphasic Pulmonary Blastoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Unresectable Middle Mediastinal Biphasic Pulmonary Blastoma.* Anticancer Res. 2015 Nov;35(11):6325-7 Authors: Gallo K, Brickman A, Warren WH, Gattuso P, Seder CW Abstract We report a case of a young male who presented with an unresectable, centrally-located classic biphasic pulmonary blastoma (CBPB) involving his bilateral mainstem bronchi and esophagus and a synchronous right testicular seminoma. CBPB is a rare and aggressive tumor that most commonly presents as a solitary mass in the periphery of the lung. Surgi... περισσότερα »

Surgical Management of Duodenal Gastrointestinal Stromal Tumors: A Case Report.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Surgical Management of Duodenal Gastrointestinal Stromal Tumors: A Case Report.* Anticancer Res. 2015 Nov;35(11):6321-4 Authors: Mrak K, Liegl-Atzwanger B, Haybaeck J, Petritsch W, Mischinger HJ, Kornprat P Abstract Gastrointestinal stromal tumors (GISTs) represent the most common mesenchymal tumor entity of the gastrointestinal tract. In fewer than 5% of cases, primary GISTs are located in the duodenum. Surgery represents the treatment of choice for localized tumor disease and remains challenging in GISTs locat...περισσότερα »

Ureteral Metastasis: Uncommon Manifestation in Prostate Cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Ureteral Metastasis: Uncommon Manifestation in Prostate Cancer.* Anticancer Res. 2015 Nov;35(11):6317-20 Authors: Schallier D, Rappe B, Carprieaux M, Vandenbroucke F Abstract Ureteral metastasis from a primary prostate cancer is a rare event in the initial diagnosis and progression of prostate cancer. We report here the case of a 72- year-old patient who was treated for castration-resistant metastatic prostate cancer involving bone, intra-abdominal lymph nodes, bilateral adrenal glands, and a small distal ureteral...περισσότερα »

Adult Pleomorphic Rhabdomyosarcoma: A Multicentre Retrospective Study.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Adult Pleomorphic Rhabdomyosarcoma: A Multicentre Retrospective Study.* Anticancer Res. 2015 Nov;35(11):6213-7 Authors: Noujaim J, Thway K, Jones RL, Miah A, Khabra K, Langer R, Kasper B, Judson I, Benson C, Kollàr A Abstract BACKGROUND: Pleomorphic rhabdomyosarcoma (RMS) is a rare sub-type of RMS. Optimal treatment remains undefined. PATIENTS AND METHODS: Between 1995 and 2014, 45 patients were diagnosed and treated in three tertiary sarcoma Centers (United Kingdom, Switzerland and Germany). Treatment characteris... περισσότερα »

Severe Hypoglycemia Caused by Recurrent Sarcomatoid Carcinoma in the Pelvic Cavity: A Case Report.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Severe Hypoglycemia Caused by Recurrent Sarcomatoid Carcinoma in the Pelvic Cavity: A Case Report.* Medicine (Baltimore). 2015 Oct;94(42):e1577 Authors: Fang C, Fan CW, Yu YY, Wang C, Yang L, Li Y, Mo XM, Zhou ZG Abstract Nonislet cell tumor hypoglycemia (NICTH) is a paraneoplastic syndrome characterized by persistent, severe hypoglycemia in different tumor types of mesochymal or epithelial origin; however, NICTH is infrequently induced by sarcomatoid carcinoma (SC). Despite ...περισσότερα »

Ovarian clear cell carcinoma, outcomes by stage: the MSK experience.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Ovarian clear cell carcinoma, outcomes by stage: the MSK experience.* Gynecol Oncol. 2015 Nov;139(2):236-41 Authors: Shu CA, Zhou Q, Jotwani AR, Iasonos A, Leitao MM, Konner JA, Aghajanian CA Abstract OBJECTIVE: Ovarian clear cell carcinomas (OCCCs) are rare, and uncertainty exists as to the optimal treatment paradigm and validity of the FIGO staging system, especially in early-stage disease. METHODS: We performed a retrospective cohort study of all OCCC patients diagnosed and treated at Memorial Sloan Kettering C... περισσότερα »

Gestational trophoblastic neoplasia after spontaneous human chorionic gonadotropin normalization following molar pregnancy evacuation.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Gestational trophoblastic neoplasia after spontaneous human chorionic gonadotropin normalization following molar pregnancy evacuation.* Gynecol Oncol. 2015 Nov;139(2):283-7 Authors: Braga A, Maestá I, Matos M, Elias KM, Rizzo J, Viggiano MG Abstract OBJECTIVE: To evaluate the risk of gestational trophoblastic neoplasia (GTN) after spontaneous human chorionic gonadotropin normalization in postmolar follow-up. METHODS: Retrospective chart review of 2284 consecutive cases of hydatidiform mole with spontaneous normali... περισσότερα »

Sclerosing Pneumocytoma with a Wax-and-Wane Pattern of Growth: A Case Report on Computed Tomography and Magnetic Resonance Imaging Findings and a Literature Review.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1V0fVJI] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Sclerosing Pneumocytoma with a Wax-and-Wane Pattern of Growth: A Case Report on Computed Tomography and Magnetic Resonance Imaging Findings and a Literature Review.* Korean J Radiol. 2015 Jul-Aug;16(4):947-50 Authors: Kim YP, Lee S, Park HS, Park CH, Kim TH Abstract Sclerosing pneumocytoma (SP) of the lung is a rare benign neoplasm. Here, we describe an unusual presentation of SP with a wax-and-wane pattern of growth in a 47-year-old woman. Tumor diameter decreased over a 3-year follow-...περισσότερα »

Sporadic Retinoblastoma and Pilocytic Astrocytoma: A Rare Association of Two Tumors.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Sporadic Retinoblastoma and Pilocytic Astrocytoma: A Rare Association of Two Tumors.* Pediatr Blood Cancer. 2015 Dec;62(12):2245-6 Authors: De Ioris MA, Carai A, Valente P, Angioni A, Randisi F, Cozza R, Romanzo A, Marras CE, Mastronuzzi A PMID: 26173175 [PubMed - indexed for MEDLINE] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1V0fYoO via IFTTT

[Primary perivascular epitheloid cell tumour (PEComa) of the liver - is a new entity of the liver tumors?].

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1SvbKVd] Related Articles *[Primary perivascular epitheloid cell tumour (PEComa) of the liver - is a new entity of the liver tumors?].* Z Gastroenterol. 2015 May;53(5):399-408 Authors: Panahova S, Rempp H, Sipos B, Malek NP, Boozari B Abstract Perivascular epitheloid cell tumor (PEComa) is a rare tumor, characterized by dual Expression of smooth muscle and melanocytic markers. Due to the development of diagnostic procedures, we now diagnose PEComa more often. We report about a case of PEComa of the liver as an accidental finding. We analyze the clinic... περισσότερα »

Pharmaceutical Formulation of HSA hybrid coated Iron Oxide Nanoparticles for Magnetic Drug Targeting.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Pharmaceutical Formulation of HSA hybrid coated Iron Oxide Nanoparticles for Magnetic Drug Targeting.* Eur J Pharm Biopharm. 2016 Feb 5; Authors: Zaloga J, Pöttler M, Leitinger G, Friedrich RP, Almer G, Lyer S, Baum E, Tietze R, Heimke-Brinck R, Mangge H, Dörje F, Lee G, Alexiou C Abstract In this work we present a new formulation of superparamagnetic iron oxide nanoparticles (SPIONs) for Magnetic Drug Targeting. The particles were reproducibly synthesised from current good manufacturing practice (cGMP) - grade substances. They were surface coated using fatty acids as anchoring ... περισσότερα »

The Deltopectoral Flap Revisited: The Internal Mammary Artery Perforator Flap.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*The Deltopectoral Flap Revisited: The Internal Mammary Artery Perforator Flap.* J Craniofac Surg. 2016 Feb 5; Authors: Ibrahim A, Atiyeh B, Karami R, Adelman DM, Papazian NJ Abstract Pharyngo-esophageal and tracheostomal defects pose a challenge in head and neck reconstruction whenever microanastomosis is extremely difficult in hostile neck that is previously dissected and irradiated. The deltopectoral (DP) flap was initially described as a pedicled flap for such reconstruction with acceptable postoperative results. A major drawback is still that the DP flap is based on 3 perfor...περισσότερα »

To the Editor

Alexandros G. SfakianakisστοΘεραπείαΠριν από 1 ώρα
Publication date: Available online 8 February 2016 *Source:*Clinical Therapeutics Author(s): Xiulu Ruan from Pharmacology via ola Kala on Inoreader http://ift.tt/1mphxR8 via IFTTT

Improvement of Pediatric Drug Development: Regulatory and Practical Frameworks

Alexandros G. SfakianakisστοΘεραπείαΠριν από 1 ώρα
Publication date: Available online 8 February 2016 *Source:*Clinical Therapeutics Author(s): Katusra Tsukamoto, Kelly A. Carroll, Taku Onishi, Naoki Matsumaru, Daniel Brasseur, Hidefumi Nakamura PurposeA dearth in pediatric drug development often leaves pediatricians with no alternative but to prescribe unlicensed or off-label drugs with a resultant increased risk of adverse events. We present the current status of pediatric drug development and, based on our data analysis, clarify the problems in this area. Further action is proposed to improve the drug development that has pediatr...περισσότερα »

Pharmacokinetic and Pharmacodynamic Effects of Multiple-Dose Administration of Omarigliptin, a Once-Weekly Dipeptidyl Peptidase-4 Inhibitor, in Obese Participants With and Without Type 2 Diabetes Mellitus

Alexandros G. SfakianakisστοΘεραπείαΠριν από 1 ώρα
Publication date: Available online 9 February 2016 *Source:*Clinical Therapeutics Author(s): Carol Addy, Daniel Tatosian, Xiaoli S. Glasgow, Isaias N. Gendrano, Eunkyung Kauh, Ashley Martucci, Amy O. Johnson-Levonas, RN Diana Selverian, Catherine Z. Matthews, Marie Gutierrez, John A. Wagner, S. Aubrey Stoch PurposeOmarigliptin (MK-3102) is a potent, oral, long-acting dipeptidyl peptidase (DPP)-4 inhibitor approved in Japan and in global development as a once-weekly treatment for type 2 diabetes mellitus (T2DM). The aim of this study was to investigate the pharmacokinetic (PK) and ph...περισσότερα »

Adenoid cystic carcinoma of head and neck: A single institutional analysis of 66 patients treated with multi-modality approach.

Adenoid cystic carcinoma of head and neck: A single institutional analysis of 66 patients treated with multi-modality approach. Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):166-171 Authors: Gandhi AK, Roy S, Biswas A, Bhasker S, Sharma A, Thakar A, Mohanti BK Abstract BACKGROUND: Adenoid cystic carcinoma (ACC) accounts for 1% of all head and neck (HN) […]

Metronomic chemotherapy in platinum-insensitive failures and/or early failures postmultimodality management in oral cancers.

Metronomic chemotherapy in platinum-insensitive failures and/or early failures postmultimodality management in oral cancers. Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):161-165 Authors: Patil VM, Noronha V, Joshi A, Pinninti R, Dhumal S, Bhattacharjee A, Prabhash K Abstract PURPOSE: Oral cancer patients with platinum-resistant disease and or early failures have limited treatment options. This analysis was planned […]

Neoadjuvant chemotherapy in oral cancers: Selecting the right patients.

Neoadjuvant chemotherapy in oral cancers: Selecting the right patients. Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):148-153 Authors: Vishak S, Rangarajan B, Kekatpure VD Abstract The standard of care treatment for oral squamous cell carcinoma (OSCC) at present, consist of surgical resection followed by adjuvant radiotherapy and chemotherapy as indicated. Despite recent advances the overall prognosis […]

Indian Council of Medical Research consensus document for the management of tongue cancer.

Indian Council of Medical Research consensus document for the management of tongue cancer. Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):140-145 Authors: D’Cruz AK, Sharma S, Agarwal JP, Thakar A, Teli A, Arya S, Desai C, Chaturvedi P, Sebastian P, Verghese BT, Kane S, Sucharita V, Kaur T, Shukla DK, Rath GK Abstract The document is […]

Commentary on Elective versus therapeutic neck dissection in node-negative oral cancer.

Commentary on Elective versus therapeutic neck dissection in node-negative oral cancer. Indian J Med Paediatr Oncol. 2015 Jul-Sep;36(3):137-139 Authors: Kuriakose MA PMID: 26855519 [PubMed – as supplied by publisher] from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K9nNbj via IFTTT

Estimation of Tissue Optical Parameters with Hyperspectral Imaging and Spectral Unmixing.

Estimation of Tissue Optical Parameters with Hyperspectral Imaging and Spectral Unmixing. Proc SPIE Int Soc Opt Eng. 2015 Mar 17;9417 Authors: Lu G, Qin X, Wang D, Chen ZG, Fei B Abstract Early detection of oral cancer and its curable precursors can improve patient survival and quality of life. Hyperspectral imaging (HSI) holds the potential […]

Multiportal combined transnasal transoral transpharyngeal endoscopic approach for selected skull base cancers.

Multiportal combined transnasal transoral transpharyngeal endoscopic approach for selected skull base cancers. Head Neck. 2016 Feb 8; Authors: Turri-Zanoni M, Battaglia P, Dallan I, Locatelli D, Castelnuovo P Abstract BACKGROUND: Minimally invasive endoscopic endonasal approaches to the ventral skull base have evolved considerably over the past several years. However, where there is a lateral extension […]

Dysgenetic polycystic disease of the minor and submandibular salivary glands.

Dysgenetic polycystic disease of the minor and submandibular salivary glands. Head Neck. 2016 Feb 8; Authors: Koudounarakis E, Willems S, Karakullukcu B Abstract BACKGROUND: Dysgenetic polycystic salivary gland disease is a rare pathology. No case of minor salivary gland involvement has been reported in the literature. METHODS: A female patient presented with bilateral tumors of […]

To the Editor

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 8 February 2016 Source:Clinical Therapeutics Author(s): Xiulu Ruan from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mphxR8 via IFTTT

Improvement of Pediatric Drug Development: Regulatory and Practical Frameworks

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 8 February 2016 Source:Clinical Therapeutics Author(s): Katusra Tsukamoto, Kelly A. Carroll, Taku Onishi, Naoki Matsumaru, Daniel Brasseur, Hidefumi Nakamura PurposeA dearth in pediatric drug development often leaves pediatricians with no alternative but to prescribe unlicensed or off-label drugs with a resultant increased risk of adverse events. We present the current status… Continue reading Improvement of Pediatric Drug Development: Regulatory and Practical Frameworks

Pharmacokinetic and Pharmacodynamic Effects of Multiple-Dose Administration of Omarigliptin, a Once-Weekly Dipeptidyl Peptidase-4 Inhibitor, in Obese Participants With and Without Type 2 Diabetes Mellitus

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 9 February 2016 Source:Clinical Therapeutics Author(s): Carol Addy, Daniel Tatosian, Xiaoli S. Glasgow, Isaias N. Gendrano, Eunkyung Kauh, Ashley Martucci, Amy O. Johnson-Levonas, RN Diana Selverian, Catherine Z. Matthews, Marie Gutierrez, John A. Wagner, S. Aubrey Stoch PurposeOmarigliptin (MK-3102) is a potent, oral, long-acting dipeptidyl peptidase (DPP)-4 inhibitor approved in Japan… Continue reading Pharmacokinetic and Pharmacodynamic Effects of Multiple-Dose Administration of Omarigliptin, a Once-Weekly Dipeptidyl Peptidase-4 Inhibitor, in Ob... περισσότερα »

Information for Readers

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QSB2wq via IFTTT

Bilateral palatal ulcers in a patient on immunosuppressive therapy

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 Author(s): Anastasia Shamsuyarova, Zeina Ghorab, Kevin Higgins, Hagen Klieb from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1KCy3bU via IFTTT

Contents

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QSB4Ew via IFTTT

The Role of Maternal Cardiac Vagal Control in the Association between Depressive Symptoms and Gestational Hypertension

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 8 February 2016 Source:Biological Psychology Author(s): Codie R. Rouleau, Lianne M. Tomfohr-Madsen, Tavis S. Campbell, Nicole Letourneau, Maeve O’Beirne, Gerald F. Giesbrecht Reduced cardiac vagal control, indexed by relatively lower high-frequency heart rate variability (HF-HRV), is implicated in depressed mood and hypertensive disorders among non-pregnant adults whereas research in pregnancy is… Continue reading The Role of Maternal Cardiac Vagal Control in the Association between Depressive Symptoms and Gestational Hypertension

Scientists discover a unique mechanism for a high-risk leukaemia https://t.co/PmmbVdCUnL

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Scientists discover a unique mechanism for a high-risk leukaemia https://t.co/PmmbVdCUnL from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/697002038308302848 via IFTTT

Vorwort von Prof. Dr. Hans-Christoph Steinhausen

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1Q500Fs via IFTTT

Not fit for purpose: the ethical guidelines of the Indian Council of Medical Research

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1Q500p6 via IFTTT

Normative data on audiovisual speech integration using sentence recognition and capacity measures.

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 2 ώρες
*Normative data on audiovisual speech integration using sentence recognition and capacity measures.* Int J Audiol. 2016 Feb 6;:1-9 Authors: Altieri N, Hudock D Abstract OBJECTIVE: The ability to use visual speech cues and integrate them with auditory information is important, especially in noisy environments and for hearing-impaired (HI) listeners. Providing data on measures of integration skills that encompass accuracy and processing speed will benefit researchers and clinicians. DESIGN: The study consisted of two experiments: First, accuracy scores were obtained using City Univ... περισσότερα »

Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 2 ώρες
*Fitting recommendations and clinical benefit associated with use of the NAL-NL2 hearing-aid prescription in Nucleus cochlear implant recipients.* Int J Audiol. 2016 Feb 6;:1-6 Authors: English R, Plant K, Maciejczyk M, Cowan R Abstract OBJECTIVE: For a group of cochlear implant recipients, who use hearing aids in the contralateral ear, the benefit of NAL-NL2 relative to a recipients' own prescription was assessed. Whether there was a preferred frequency response and/or gain deviation from NAL-NL2 was then investigated. DESIGN: Speech recognition and self-reported ratings of benefi...περισσότερα »

Editorial Board

Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QSB33j via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Society Page

Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QSB2MP via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Information for Readers

Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QSB2wq via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Bilateral palatal ulcers in a patient on immunosuppressive therapy

Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 Author(s): Anastasia Shamsuyarova, Zeina Ghorab, Kevin Higgins, Hagen Klieb from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1KCy3bU via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Contents

Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QSB4Ew via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Spindle cell variant of ameloblastic carcinoma: a case report and literature review

Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 Author(s): Yuki Matsushita, Shuichi Fujita, Souichi Yanamoto, Shin-ichi Yamada, Satoshi Rokutanda, Kentaro Yamashita, Tohru Ikeda, Masahiro Umeda Spindle cell variant of ameloblastic carcinoma is an extremely rare tumor. Severe dedifferentiated spindle cell variants are diagnostically challenging, particularly in […]

Basal cell adenoma with S-100 positive stroma: a case report and literature review

Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 Author(s): Emanuela Ortolani, Antonella Polimeni, Libero Lauriola, Antonella Coli Basal cell adenoma (BCA) of the salivary gland with presence of abundant S-100–positive stromal cells has been rarely reported. A case occurring in a 75-year-old man is presented here, […]

Chemotherapy-Induced Fatigue Correlates With Higher Fatigue Scores Before Treatment.

CONCLUSION: We conclude that fatigue induced by chemotherapy is common and consistently associated with higher fatigue scores before treatment. Screening for fatigue before chemotherapy may help to identify patients who are prone to develop CIF. PMID: 26847709 [PubMed – as supplied by publisher] (Source: The American Journal of Hospice and Palliative Care) from #Medicine-SfakianakisAlexandros via […]

miR-26b-3p Regulates Human Umbilical Cord-Derived Mesenchymal Stem Cell Proliferation by Targeting Estrogen Receptor

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 2 ώρες
Stem Cells and Development , Vol. 0, No. 0. from Cell via ola Kala on Inoreader http://ift.tt/1PLCy4u via IFTTT

Depletion of SAM50 Specifically Targets BCR-ABL-Expressing Leukemic Stem and Progenitor Cells by Interfering with Mitochondrial Functions

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 2 ώρες
Stem Cells and Development , Vol. 0, No. 0. from Cell via ola Kala on Inoreader http://ift.tt/1V06dH3 via IFTTT

Clinical course among cases of acute liver failure of indeterminate diagnosis

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 2 ώρες
The Journal of Pediatrics from #Medicine via ola Kala on Inoreader http://ift.tt/1TPHqqK Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Basal cell adenoma with S-100 positive stroma: a case report and literature review

Publication date: March 2016 Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 3 Author(s): Emanuela Ortolani, Antonella Polimeni, Libero Lauriola, Antonella Coli Basal cell adenoma (BCA) of the salivary gland with presence of abundant S-100–positive stromal cells has been rarely reported. A case occurring in a 75-year-old man is presented here, […]

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