Outcomes of an International Audiology Service-Learning Study-Abroad Program
Outcomes of an International Audiology
Service-Learning Study-Abroad Program: PurposeThe purpose of this study was to
evaluate students' academic and civic learning, with particular interest
in cultural competence, gained through participation in the Speech, Language,
and Hearing Sciences in Zambia study-abroad program. MethodTwelve female
students participated in the program. Quantitative data collected included pre-
and postprogram administration of the Public Affairs Scale (Levesque-Bristol
& Cornelius-White, 2012) to measure changes in participants'
civic learning. Qualitat...περισσότερα »
Impedance Changes and Fibrous Tissue Growth after Cochlear Implantation Are Correlated and Can Be Reduced Using a Dexamethasone Eluting Electrode
Impedance Changes and Fibrous Tissue Growth after
Cochlear Implantation Are Correlated and Can Be Reduced Using a Dexamethasone
Eluting Electrode: Background The efficiency of cochlear implants (CIs) is
affected by postoperative connective tissue growth around the electrode array.
This tissue formation is thought to be the cause behind post-operative increases
in impedance. Dexamethasone (DEX) eluting CIs may reduce fibrous tissue growth
around the electrode array subsequently moderating elevations in impedance of
the electrode contacts.Methods For this study, DEX was incorpora...περισσότερα »
Cross-Modal and Intra-Modal Characteristics of Visual Function and Speech Perception Performance in Postlingually Deafened, Cochlear Implant Users
Cross-Modal and Intra-Modal Characteristics of
Visual Function and Speech Perception Performance in Postlingually Deafened,
Cochlear Implant Users: Evidence of visual-auditory cross-modal plasticity in
deaf individuals has been widely reported. Superior visual abilities of deaf
individuals have been shown to result in enhanced reactivity to visual events
and/or enhanced peripheral spatial attention. The goal of this study was to
investigate the association between visual-auditory cross-modal plasticity and
speech perception in post-lingually deafened, adult cochlear implant (CI)
use...περισσότερα »
Stereotactic LINAC-Radiosurgery for Glomus Jugulare Tumors
Stereotactic LINAC-Radiosurgery for Glomus Jugulare
Tumors: A Long-Term Follow-Up of 27 Patients: Background The optimal treatment
of glomus jugulare tumors (GJTs) remains controversial. Due to the critical
location, microsurgery still provides high treatment-related morbidity and a
decreased quality of life. Thus, we performed stereotactical radiosurgery (SRS)
for the treatment of GJTs and evaluated the long-term outcome.Methods Between
1991 and 2011, 32 patients with GJTs underwent SRS using a linear accelerator
(LINAC) either as primary or salvage therapy. Twenty-seven patie...περισσότερα »
Dangerous practices with coal-burning stoves inside the home accounted for the majority of CO poisoning incidents. Community health centers should provide instruction to and supervision of residents on proper installation and use of home heating stoves as well as inspection of installation.
Risk Factors for Non-Occupational Carbon Monoxide
Poisoning: Anshan Prefecture, Liaoning Province, China, 2011–2012: Background
Carbon monoxide (CO) poisoning can be fatal but is preventable. From October
2010 to February 2011, Anshan Prefecture reported 57 cases of non-occupational
CO poisoning in District A, with two deaths. We conducted an investigation to
identify risk factors and recommend preventive measures.Methods We defined a
possible case of non-occupational CO poisoning as onset of at least two of the
following symptoms: fatigue, headache, dizziness, nausea, vomitin...περισσότερα »
Primary Hyperventilation in the Emergency Department: A First Overview
Primary Hyperventilation in the Emergency
Department: A First Overview: Background Primary hyperventilation is defined as
a state of alveolar ventilation in excess of metabolic requirements, leading to
decreased arterial partial pressure of carbon dioxide. The primary aim of this
study was to characterise patients diagnosed with primary hyperventilation in
the ED.Methods Our retrospective cohort study comprised adult (≥16 years)
patients admitted to our ED between 1 January 2006 and 31 December 2012 with the
primary diagnosis of primary (=psychogenic) hyperventilation.Result...περισσότερα »
Risk Factors for Prolonged Treatment of Whiplash-Associated Disorders
Risk Factors for Prolonged Treatment of
Whiplash-Associated Disorders: Objectives Whiplash-associated disorders (WAD)
are the most common injuries that are associated with car collisions in Japan
and many Western countries. However, there is no clear evidence regarding the
potential risk factors for poor recovery from WAD. Therefore, we used an online
survey of the Japanese population to examine the association between potential
risk factors and the persistence of symptoms in individuals with WAD.Materials
and Methods An online survey was completed by 127,956 participants,
inclu...περισσότερα »
Patterns of Adverse Drug Reactions in Different Age Groups
Patterns of Adverse Drug Reactions in Different Age
Groups: Analysis of Spontaneous Reports by Community Pharmacists: Purpose To
evaluate the clinical manifestations and causative drugs associated with adverse
drug reactions (ADRs) spontaneously reported by community pharmacists and to
compare the ADRs by age.Methods ADRs reported to the Regional Pharmacovigilance
Center of the Korean Pharmaceutical Association by community pharmacists from
January 2013 to June 2014 were included. Causality was assessed using the
WHO-Uppsala Monitoring Centre system. The patient population was c...περισσότερα »
Mal de debarquement syndrome (MdDS) is a disorder of chronic self-motion perception that occurs though entrainment to rhythmic background motion, such as from sea voyage, and involves the perception of low-frequency rocking that can last for months or years.
Voxel Based Morphometry Alterations in Mal de
Debarquement Syndrome: Background Mal de debarquement syndrome (MdDS) is a
disorder of chronic self-motion perception that occurs though entrainment to
rhythmic background motion, such as from sea voyage, and involves the perception
of low-frequency rocking that can last for months or years. The neural basis of
this persistent sensory perception abnormality is not well understood.Methods We
investigated grey matter volume differences underlying persistent MdDS by
performing voxel-based morphometry on whole brain and pre-specified
ROI...περισσότερα »
Human Vection Perception Using Inertial Nulling and Certainty Estimation: The Effect of Migraine History
Human Vection Perception Using Inertial Nulling and
Certainty Estimation: The Effect of Migraine History: Vection is an illusory
perception of self-motion that can occur when visual motion fills the majority
of the visual field. This study examines the effect of the duration of visual
field movement (VFM) on the perceived strength of self-motion using an inertial
nulling (IN) and a magnitude estimation technique based on the certainty that
motion occurred (certainty estimation, CE). These techniques were then used to
investigate the association between migraine diagnosis and the str...περισσότερα »
Prevalence and Predictors of Somatic Symptoms among Child and Adolescents with Probable Posttraumatic Stress Disorder
A Cross-Sectional Study Conducted in 21 Primary
and Secondary Schools after an Earthquake: Purpose To explore the prevalence
rates and predictors of somatic symptoms among child and adolescent survivors
with probable posttraumatic stress disorder (PTSD) after an earthquake.Methods A
total of 3053 students from 21 primary and secondary schools in Baoxing County
were administered the Patient Health Questionnaire-13 (PHQ-13), a short version
of PHQ-15 without the two items about sexuality and menstruation, the Children's
Revised Impact of Event Scale (CRIES), and the self-made Ea...περισσότερα »
Period Prevalence of Dizziness and Vertigo in Adolescents
Period Prevalence of Dizziness and Vertigo in
Adolescents: Objectives To assess the period prevalence and severity of
dizziness and vertigo in adolescents.Methods In 1661 students in 8th-10th grade
in twelve grammar schools in Munich, Germany information on vertigo/dizziness
was assessed by a questionnaire in the class room setting. Three month
prevalence of dizziness/vertigo was estimated; symptoms were categorized as
orthostatic dizziness, spinning vertigo, swaying vertigo or unspecified
dizziness. Duration of symptoms and impact on daily life activities were
assessed.Result...περισσότερα »
Persistent Postural-Perceptual Dizziness: A Matter of Higher, Central Dysfunction?
Persistent Postural-Perceptual Dizziness: A Matter
of Higher, Central Dysfunction?: Objective Persistent postural-perceptual
dizziness (PPPD) is the most common vestibular disorder in the age group between
30 and 50 years. It is considered to be based on a multisensory maladjustment
involving alterations of sensory response pattern including vestibular, visual
and motion stimuli. Previous data supported a link between vestibular and pain
mechanism. The aim of the study was to investigate whether other sensory inputs
such as pain stimuli might be altered in terms of a more widesprea...περισσότερα »
Neurosensory Symptom Complexes after Acute Mild Traumatic Brain Injury
Neurosensory Symptom Complexes after Acute Mild
Traumatic Brain Injury: Mild Traumatic Brain Injury (mTBI) is a prominent public
health issue. To date, subjective symptom complaints primarily dictate
diagnostic and treatment approaches. As such, the description and qualification
of these symptoms in the mTBI patient population is of great value. This
manuscript describes the symptoms of mTBI patients as compared to controls in a
larger study designed to examine the use of vestibular testing to diagnose mTBI.
Five symptom clusters were identified: Post-Traumatic Headache/Migraine,
Na...περισσότερα »
Oculomotor Deficits after Chemotherapy in Childhood
Oculomotor Deficits after Chemotherapy in
Childhood: Advances in the diagnosis and treatment of pediatric malignancies
have substantially increased the number of childhood cancer survivors. However,
reports suggest that some of the chemotherapy agents used for treatment can
cross the blood brain barrier which may lead to a host of neurological symptoms
including oculomotor dysfunction. Whether chemotherapy at young age causes
oculomotor dysfunction later in life is unknown. Oculomotor performance was
assessed with traditional and novel methods in 23 adults (mean age 25.3 years,
trea...περισσότερα »
Arterial Spin Labeling Perfusion Study in the Patients with Subacute Mild Traumatic Brain Injury
Arterial Spin Labeling Perfusion Study in the
Patients with Subacute Mild Traumatic Brain Injury: Background This study uses a
MRI technique, three-dimension pulse continuous arterial spin labeling
(3D-PCASL), to measure the patient’s cerebral blood flow (CBF) at the subacute
stage of mild traumatic brain injury (MTBI) in order to analyze the relationship
between cerebral blood flow and neurocognitive deficits.Objective To provide the
relationship between cortical CBF and neuropsychological dysfunction for the
subacute MTBI patients.Methods After MTBI, perfusion MR imaging...περισσότερα »
Tinnitus Self-Efficacy and Other Tinnitus Self-Report Variables in Patients With and Without Post-Traumatic Stress Disorder.
Tinnitus Self-Efficacy and Other Tinnitus
Self-Report Variables in Patients With and Without Post-Traumatic Stress
Disorder.: Objective: Individuals with tinnitus and co-occurring psychological
conditions typically rate their tinnitus as more disturbing than individuals
without such comorbidities. Little is known about how tinnitus self-efficacy, or
the confidence that individuals have in their abilities to successfully manage
the effects of tinnitus, is influenced by mental or psychological health (PH)
status. The purpose of this study was to examine the influence of psychological
...περισσότερα »
A Wide-diameter Bone-anchored Hearing Implant and a Surgical Technique With Tissue Preservation.
Clinical Outcome of a Wide-diameter Bone-anchored
Hearing Implant and a Surgical Technique With Tissue Preservation.: Objective:
To investigate the clinical outcome of a surgical technique with tissue
preservation for a wide bone-anchored hearing implant concerning postoperative
complications, skin reactions, implant loss, and implant stability.Study Design:
Consecutive, prospective case series.Setting: Tertiary referral center.Patients:
Twenty-four adult patients with normal skin quality were enrolled.
Intervention(s): Implantation of bone-anchored implant was performed using
a...περισσότερα »
Psychiatric Disorders in Intractable Peripheral Vertiginous Patients
Quantitative Analysis of Psychiatric Disorders in
Intractable Peripheral Vertiginous Patients: A Prospective Study.: Objective: To
investigate the correlation between psychological disorder and vestibular
dysfunction in patients suffering from intractable peripheral vertigo.Study
Design: Prospective study.Setting: In-patients in a university hospital.Methods:
Prospective design of 26 intractable peripheral vertiginous patients with
peripheral vestibular dysfunction and 20 controls recruited from the EENT
hospital. Hospital Anxiety and Depression scale, Self-rating Anxiety
scale,...περισσότερα »
Endoscopic Keyhole Middle Fossa Craniotomy Approach to the Superior Semicircular Canal.
Cadaveric Study of an Endoscopic Keyhole Middle
Fossa Craniotomy Approach to the Superior Semicircular Canal.: Objective:
Demonstrate that an endoscopic keyhole approach to the middle cranial fossa is
technically feasible for repair of semicircular canal dehiscence.Study Design:
Cadaveric technical feasibility/methods development study.Setting: Tertiary care
military medical center.Patients: Three fresh cadaveric heads (six sides).
Intervention(s): Endoscopic minimally invasive approach to the middle cranial
fossa using the Medtronic Fusion Guidance system.Main Outcome
Measure(...περισσότερα »
Disrupted Functional Brain Connectome in Unilateral Sudden Sensorineural Hearing Loss
Disrupted Functional Brain Connectome in
Unilateral Sudden Sensorineural Hearing Lossvia Hearing ResearchPublication
date: Available online 9 March 2016*Source:*Hearing ResearchAuthor(s): Haibo Xu,
Wenliang Fan, Xueyan Zhao, Jing Li, Wenjuan Zhang, Ping Lei, Yuan Liu, Haha
Wang, Huamao Cheng, Hong ShiSudden sensorineural hearing loss (SSNHL) is
generally defined as sensorineural hearing loss of 30 dB or greater over at
least three contiguous audiometric frequencies and within a three-day period.
This hearing loss is usually unilateral and can be associated with tinnitus and
verti...περισσότερα »
Impulse noise injury prediction based on the cochlear energy
Impulse noise injury prediction based on the
cochlear energyvia Hearing ResearchPublication date: Available online 9 March
2016*Source:*Hearing ResearchAuthor(s): Brissi Zagadou, Philemon Chan, Kevin Ho,
David ShelleyThe current impulse noise criteria for the protection against
impulse noise injury do not incorporate an objective measure of hearing
protection. A new biomechanically-based model has been developed based on
improvement of the Auditory Hazard Assessment Algorithm for the Human (AHAAH)
using the integrated cochlear energy (ICE) as the damage risk correlate (DRC).
The m...περισσότερα »
Injury grade is a predictor of aortic-related death among patients with blunt thoracic aortic injury
Journal of Vascular Surgeryfrom Emergency Medicine
via xlomafota13 on Inoreader http://ift.tt/1SySdWk
Cerebral oximetry and capnography in excessive hyperventilated pediatric increase ICP patients: case series demonstrating the physiologic premise, excessive hyperventilation leads to decreased regional cerebral blood flow and oxygenation
The American Journal of Emergency Medicinefrom
Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QLcovD
Efficacy of simulation application SimMon for emergency response training
The American Journal of Emergency Medicinefrom
Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1SySbxN
Knowledge about Hepatitis C Virus Infection and Acceptability of Testing in the 1945–1965 Birth Cohort (Baby Boomers) Presenting to a Large Urban Emergency Department: A Pilot Study
The Journal of Emergency Medicinefrom Emergency
Medicine via xlomafota13 on Inoreader http://ift.tt/1QLcofa
Orbital compartment syndrome due to acute hemorrhage within an orbital lymphatic malformation: emergency treatment with percutaneous sclerotherapy
Journal of Vascular and Interventional Radiology
from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1SySdFK
Clinical effectiveness, quality of life and cost-effectiveness of Flaminal® versus Flamazine® in the treatment of partial thickness burns: study protocol for a randomized controlled trial
Trialsfrom Emergency Medicine via xlomafota13 on
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A quick and easy delirium assessment for non-physician research personnel
The American Journal of Emergency Medicinefrom
Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1SySdpo
Postoperative negative pressure therapy significantly reduces flap complications in distally based peroneus brevis flaps: Experiences from 74 cases
Injuryfrom Emergency Medicine via xlomafota13 on
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The impact of transfer on pediatric trauma outcomes
Journal of Pediatric Surgeryfrom Emergency Medicine
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Prevalence of marijuana use disorders in the United States between 2001-2001 and 2012-2013
The Journal of Emergency Medicinefrom Emergency
Medicine via xlomafota13 on Inoreader http://ift.tt/1QLcnIe
Outcomes of basic versus advanced life support for out-of-hospital medical emergencies
The Journal of Emergency Medicinefrom Emergency
Medicine via xlomafota13 on Inoreader http://ift.tt/1SySaKh
Improved identification of sternal injuries with multi-detector computed tomography (MDCT): sagittal reconstructions
Clinical Imagingfrom Emergency Medicine via
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Comparison of the VivaSight™ single lumen endotracheal tube and the Macintosh laryngoscope for emergency intubation by experienced paramedics in a standardized airway manikin with restricted access. A randomized, crossover trial
The American Journal of Emergency Medicinefrom
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Progesterone for traumatic brain injury: a meta-narrative review of randomized controlled trials
World Neurosurgeryfrom Emergency Medicine via
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Analgesic adherence in recently discharged trauma patients: An integrative literature review
Pain Management Nursingfrom Emergency Medicine via
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The impact of a preauthorization policy on the after-hours utilization of emergency department computed tomography imaging
Academic Radiologyfrom Emergency Medicine via
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Early trends among seven recommendations from the choosing wisely campaign
The Journal of Emergency Medicinefrom Emergency
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Prevalence of chronic compartment syndrome of the legs: Implications for clinical diagnostic criteria and therapy
Scandinavian Journal of Painfrom Emergency Medicine
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Post-trauma mortality increase at age 60: a cut-off for defining elderly?
The American Journal of Surgeryfrom Emergency
Medicine via xlomafota13 on Inoreader http://ift.tt/1SySad8
Impact of an emergency department observation unit management algorithm for atrial fibrillation
Journal of the American Heart Associationfrom
Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1QLcm74
Tough to Swallow: Esophageal Food Impaction from Esophageal Amyloidosis
from #Esophageal Cancer via a.lsfakia on Inoreader
http://ift.tt/1pfUvytvia IFTTT
Patterns of lymphatic spread and the management of eyelid carcinomas
Patterns of lymphatic spread and the management of
eyelid carcinomasvia Auris Nasus LarynxPublication date: Available online 7
March 2016*Source:*Auris Nasus LarynxAuthor(s): Kazuki Hashimoto, Ryuji
Yasumatsu, Satoshi Toh, Hideki Shiratsuchi, Takamasa Yoshida, Kazuo Nishiyama,
Hiroshi Yoshikawa, Torahiko Nakashima, Takashi NakagawaObjectiveEyelid
carcinomas are rare, and the management strategy of regional lymph node
metastasis linked to eyelid carcinomas has not been standardized to date. The
aim of the present study was to analyze the patterns of regional metastasis and
to asses...περισσότερα »
Tracheoesophageal fistula length decreases over time
Tracheoesophageal fistula length decreases over
time: AbstractThe objectives of this study were to demonstrate that the length
of the tracheoesophageal voice prosthesis changes over time and to determine
whether the prosthesis length over time increased, decreased, or showed no
predictable change in size. A retrospective chart review was performed at a
tertiary care referral center. Patients who underwent either primary or
secondary tracheoesophageal puncture between January 2006 and August 2014 were
evaluated. Patients were excluded if the tracheoesophageal prosthesis size was
not...περισσότερα »
Extracorporeal Perfusion of Microvascular Free Flaps
Extracorporeal Perfusion of Microvascular Free
Flaps: *Conditions*: Perfusion; Complication of Perfusion*Intervention*:
Procedure: Perfusion of flaps by a special bypass system*Sponsor*: Technische
Universität MünchenThe perfusion of microvascular free flaps is inevitable for
completion of reconstruction in the head and neck area. In some patients
microvascular anastomosis is impossible because of arteriosclerotic changes,
different oncological interventions, and consecutive vessel depletion at the
neck. The aim of the project is to establish an innovative system for
e...περισσότερα »
The Oral Cavity as a Source of Febrile Neutropenia
The Oral Cavity as a Source of Febrile Neutropenia:
*Conditions*: Febrile Neutropenia; Solid Tumors; Dental Infection; Oral
Infection*Intervention*: *Sponsor*: Academisch Medisch Centrum -
Universiteit van Amsterdam (AMC-UvA)Febrile neutropenia (FN) is a clinically
important adverse effect of myelosuppressive chemotherapy. If patients present
with FN, attention is focussed on well-recognized sites of origin of infection:
the airways, urinary tracts, and skin. However, infections can be only
documented clinically in about two-third of febrile episodes, whereas a
cau...περισσότερα »
Long noncoding RNAs related to the odontogenic potential of dental mesenchymal cells in mice
Publication date: Available online 8 March 2016
*Source:*Archives of Oral BiologyAuthor(s): Yunfei Zheng, Lingfei Jia
ObjectivesThe purpose of this study is to identify the lncRNAs that are
associated with the odontogenic potential in mouse dental mesenchymal
cells.DesignThe odontogenic potential of dental mesenchymal cells was found to
be lost in the course of in vitro culture, so the lncRNA profiles were
subsequently compared between freshly-isolated and cultured dental mesenchymal
cells using RNA-sequencing. A co-expression analysis of differentially expressed
lncRNAs and coding...περισσότερα »
Eye lens dosimetry in anesthesiology: a prospective study
Abstract The eye lens is one of the most sensitive
organs for radiation injury and exposure might lead to radiation induced
cataract. Eye lens dosimetry in anesthesiology has been published in few
clinical trials and an active debate about the causality of radiation induced
cataract is still ongoing. Recently, the International Commission on
Radiological Protection (ICRP) recommended a reduction in the annual dose limit
for occupational exposure for the lens of the eye from 150 to 20 mSv, averaged
over a period of 5 years, with the dose in a single year not exceeding 50 mSv.
This ...περισσότερα »
Phase 2 Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an Oral Starting Dose of 20 mg or 14 mg Daily Will Provide Comparable Efficacy to a 24 mg Starting Dose, But Have a Better Safety Profile
Phase 2 Trial of Lenvatinib (E7080) in Subjects
With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an
Oral Starting Dose of 20 mg or 14 mg Daily Will Provide Comparable Efficacy to a
24 mg Starting Dose, But Have a Better Safety Profile: *Condition*: Thyroid
Cancer*Interventions*: Drug: Lenvatinib; Drug: Lenvatinib matching placebo
*Sponsor*: Eisai Inc.This is a multicenter, randomized, double-blind study
being conducted as a postmarketing requirement to the US Food and Drug
Administration (FDA) to evaluate whether there is a lower starting
dosa...περισσότερα »
Combination Therapies Using an Intratympanic Polymer Gel Delivery System
in the Guinea Pig Animal Model: A Safety Studyvia
International Journal of Pediatric OtorhinolaryngologyPublication date:
Available online 7 March 2016*Source:*International Journal of Pediatric
OtorhinolaryngologyAuthor(s): Douglas Sidell, Jonette A. Ward, Angad Pordal,
Carson Quimby, Michel Nassar, Daniel I. ChooObjectivesHigh dose antivirals have
been shown to cause hearing loss when applied via the intratympanic route. The
aim of this study was to determine if a combination therapy using dexamethasone
(DXA) with either Cidofovir (CDV) or Ganciclovir (GCV), in solution or in
PL...περισσότερα »
Track Recurrence After Robotic Transaxillary Thyroidectomy: A Case Report Highlighting the Importance of Controlled Surgical Indications and Addressing Unprecedented Complications
Track Recurrence After Robotic Transaxillary
Thyroidectomy: A Case Report Highlighting the Importance of Controlled Surgical
Indications and Addressing Unprecedented Complications: Author informationSohail
Bakkar, Gianluca Frustaci, Piermarco Papini, Lorenzo Fregoli, Valeria Matteucci,
Gabriele Materazzi, and Paolo MiccoliDivision of Surgery, Department of Surgical
Pathology, University Hospital of Pisa, Pisa, Italy.Address correspondence to:
*Sohail Bakkar, MD, MS**30 E, 2nd Piano, Endocrino Chirurgia**Division of
Surgery**Department of Surgical Pathology**University Hospital ...περισσότερα »
Human Papilloma virus in Juvenile Nasopharyngeal Angiofibroma
: Possible Recent trendvia American Journal of
OtolaryngologyPublication date: Available online 8 March 2016*Source:*American
Journal of OtolaryngologyAuthor(s): Mishra Anupam, Sachadeva Monica, Jain
Ankita, Shukla Mishra Nimisha, Pandey AmitaBackgroundJuvenile nasopharyngeal
angiofibroma (JNA) has witnessed a four-fold increase in the incidence at our
facility in the current decade as compared to the 1980s. With high global
incidence of human pappilloma virus (HPV) related oropharyngeal cancer in India,
we hypothesize its implication in JNA as it has not yet been
reported.Methods...περισσότερα »
Magnetic Resonance Imaging for Diagnosis of Mandibular Involvement from Head and Neck Cancers: A Systematic Review and Meta-Analysis
Magnetic Resonance Imaging for Diagnosis of
Mandibular Involvement from Head and Neck Cancers: A Systematic Review and
Meta-Analysis: Background Diagnosis of mandibular involvement caused by head and
neck cancers is critical for treatment. We performed a meta-analysis to
determine the diagnostic efficacy of MR for distinguishing mandibular
involvement caused by head and neck cancers.Methods Thirteen databases were
searched electronically and hand-searching was also done. Two reviewers
conducted study inclusion, data extractions, and quality assessment of the
studies independentl...περισσότερα »
Non-Steroidal Anti-Inflammatory Drugs Use Is Associated with Reduced Risk of Inflammation-Associated Cancers: NIH-AARP Study
Non-Steroidal Anti-Inflammatory Drugs Use Is
Associated with Reduced Risk of Inflammation-Associated Cancers: NIH-AARP Study:
Background Chronic inflammation has been linked to cancers, and use of
non-steroidal anti-inflammatory drugs (NSAIDs) has been associated with reduced
risk of several cancers. To further refine the magnitude of NSAID-related
associations, in particular for cancers related to inflammation, such as
alcohol-, infection-, obesity-, and smoking-related cancers, as well as for less
common cancers, we evaluated the use of NSAIDs and cancer risk in a very large
coho...περισσότερα »
Secondary Primary Malignancy Risk among Patients with Esophageal Cancer
Secondary Primary Malignancy Risk among Patients
with Esophageal Cancer in Taiwan: A Nationwide Population-Based Study:
Background To evaluate the risk and sites of metachronous secondary primary
malignancies (SPMs) among patients with esophageal cancer.Methods Newly
diagnosed esophageal cancer patients between 1997 and 2011 were recruited. To
avoid surveillance bias, SPMs that developed within one year were excluded.
Standardized incidence ratios (SIRs) of metachronous SPMs in these patients were
calculated by comparing to the cancer incidence in the general population. Risk
fa...περισσότερα »
Adjuvant Chemotherapy with S-1 after Curative Treatment in Patients with Squamous-Cell Carcinoma of the Head and Neck (ACTS-HNC)
Randomized Phase III Trial of Adjuvant Chemotherapy
with S-1 after Curative Treatment in Patients with Squamous-Cell Carcinoma of
the Head and Neck (ACTS-HNC): Background We conducted a phase III study to
evaluate S-1 as compared with UFT as control in patients after curative therapy
for stage III, IVA, or IVB squamous-cell carcinoma of the head and neck (SCCHN).
Patients and Methods Patients were randomly assigned to the UFT group (300 or
400 mg day-1 for 1 year) or the S-1 group (80, 100, or 120 mg day-1 for 1 year).
The primary end point was disease-free survival (DFS). Second...περισσότερα »
Alcohol and Tobacco Consumption in Head and Neck Cancer
Different Levels in Alcohol and Tobacco Consumption
in Head and Neck Cancer Patients from 1957 to 2013: Objective To provide a
precise quantification of the association between alcohol and tobacco
consumption trends in head and neck cancer patients over the past 45 years.
Methods We combined findings from all studies published until March 2014 and
evaluated the association between different levels in alcohol and tobacco
consumption and head and neck cancers through a meta-analytic approach.Results
We included 28 studies involving 13830 patients with head and neck cancer. In
p...περισσότερα »
EPHX1 Polymorphisms and the Risk of Head and Neck Cancer
Systematic Review and Meta-Analysis of the
Relationship between EPHX1 Polymorphisms and the Risk of Head and Neck Cancer:
Aim To evaluate the association between the *EPHX1 Tyr113His* and *His139Arg*
polymorphisms in the *EPHX1* gene and the risk of head and neck cancer.Materials
and Methods Studies on the association of *EPHX1 Tyr113His* and *His139Arg*
polymorphisms with HNC performed up until June 1st, 2014, were identified using
a predefined search strategy. Summary odds ratios (ORs) and 95% confidence
intervals (CIs) were used to evaluate the strength of these
associations....περισσότερα »
Age and Gender Variations in Cancer Diagnostic Intervals in 15 Cancers
Age and Gender Variations in Cancer Diagnostic
Intervals in 15 Cancers: Analysis of Data from the UK Clinical Practice Research
Datalink: Background Time from symptomatic presentation to cancer diagnosis
(diagnostic interval) is an important, and modifiable, part of the patient’s
cancer pathway, and can be affected by various factors such as age, gender and
type of presenting symptoms. The aim of this study was to quantify the
relationships of diagnostic interval with these variables in 15 cancers
diagnosed between 2007 and 2010 using routinely collected data from the Clinical
P...περισσότερα »
Metachronous Second Primary Malignancies after Head and Neck Cancer
Metachronous Second Primary Malignancies after Head
and Neck Cancer in a Korean Cohort (1993-2010): Second primary malignancy (SPM)
is the major long-term cause of patient mortality with head and neck squamous
cell carcinoma (HNSCC). As the incidence of high-risk human papillomavirus
(HPV)-related HNSCC is increasing globally, we analyzed the patterns of SPM
occurrence, the effect of the index tumor site along with attributes to HPV, and
the effect of SPM on survival in South Korean patients with head and neck cancer
(HNC). Data were retrieved from the Korea Central Cancer Registry,...περισσότερα »
The Impact of Iterative Reconstruction on Computed Tomography Radiation Dosimetry: Evaluation in a Routine Clinical Setting
The Impact of Iterative Reconstruction on Computed
Tomography Radiation Dosimetry: Evaluation in a Routine Clinical Setting:
Purpose To evaluate the effect of introduction of iterative reconstruction as a
mandated software upgrade on radiation dosimetry in routine clinical practice
over a range of computed tomography examinations.Methods Random samples of
scanning data were extracted from a centralised Picture Archiving Communication
System pertaining to 10 commonly performed computed tomography examination types
undertaken at two hospitals in Western Australia, before and after...περισσότερα »
Tumor-Associated Endothelial Cells Promote Tumor Metastasis by Chaperoning Circulating Tumor Cells and Protecting Them from Anoikis
Tumor-Associated Endothelial Cells Promote Tumor
Metastasis by Chaperoning Circulating Tumor Cells and Protecting Them from
Anoikis: Tumor metastasis is a highly inefficient biological process as millions
of tumor cells are released in circulation each day and only a few of them are
able to successfully form distal metastatic nodules. This could be due to the
fact that most of the epithelial origin cancer cells are anchorage-dependent and
undergo rapid anoikis in harsh circulating conditions. A number of studies have
shown that in addition to tumor cells, activated endothelial cells ...περισσότερα »
Cisplatin-Associated Acute Kidney Injury
Understanding the Risk Factors and Long-Term
Consequences of Cisplatin-Associated Acute Kidney Injury: An Observational
Cohort Study: Acute kidney injury (AKI) is a well-known complication of
cisplatin-based chemotherapy; however, its impact on long-term patient survival
is unclear. We sought to determine the incidence and risk factors for
development of cisplatin-associated AKI and its impact on long-term renal
function and patient survival. We identified 233 patients who received 629
cycles of high-dose cisplatin (99±9mg/m2) for treatment of head and neck cancer
between 2005 and ...περισσότερα »
Cold Atmospheric Plasma for Squamous Head and Neck Cancer
Cold Atmospheric Plasma: A Promising Complementary
Therapy for Squamous Head and Neck Cancer: Head and neck squamous cell cancer
(HNSCC) is the 7th most common cancer worldwide. Despite the development of new
therapeutic agents such as monoclonal antibodies, prognosis did not change for
the last decades. Cold atmospheric plasma (CAP) presents the most promising new
technology in cancer treatment. In this study the efficacy of a surface micro
discharging (SMD) plasma device against two head and neck cancer cell lines was
proved. Effects on the cell viability, DNA fragmentation and ap...περισσότερα »
Tumor Necrosis Factor Inhibition and Head and Neck Cancer Recurrence and Death in Rheumatoid Arthritis
Tumor Necrosis Factor Inhibition and Head and Neck
Cancer Recurrence and Death in Rheumatoid Arthritis: The objective of this
retrospective cohort study was to determine the effect of tumor necrosis factor
inhibitor (TNFi) therapy on the risk of head and neck cancer (HNC) recurrence or
HNC-attributable death in patients with rheumatoid arthritis (RA). RA patients
with HNC were assembled from the US national Veterans’ Affairs (VA)
administrative databases, and diagnoses confirmed and data collected by
electronic medical record review. The cohort was divided into those treated with
...περισσότερα »
Long noncoding RNAs related to the odontogenic potential of dental mesenchymal cells in mice
Publication date: Available online 8 March 2016
*Source:*Archives of Oral BiologyAuthor(s): Yunfei Zheng, Lingfei Jia
ObjectivesThe purpose of this study is to identify the lncRNAs that are
associated with the odontogenic potential in mouse dental mesenchymal
cells.DesignThe odontogenic potential of dental mesenchymal cells was found to
be lost in the course of in vitro culture, so the lncRNA profiles were
subsequently compared between freshly-isolated and cultured dental mesenchymal
cells using RNA-sequencing. A co-expression analysis of differentially expressed
lncRNAs and coding...περισσότερα »
Impulse noise injury prediction based on the cochlear energy
Publication date: Available online 9 March 2016
*Source:*Hearing ResearchAuthor(s): Brissi Zagadou, Philemon Chan, Kevin Ho,
David ShelleyThe current impulse noise criteria for the protection against
impulse noise injury do not incorporate an objective measure of hearing
protection. A new biomechanically-based model has been developed based on
improvement of the Auditory Hazard Assessment Algorithm for the Human (AHAAH)
using the integrated cochlear energy (ICE) as the damage risk correlate (DRC).
The model parameters have been corrected using the latest literature data. The
anoma...περισσότερα »
Disrupted Functional Brain Connectome in Unilateral Sudden Sensorineural Hearing Loss
Publication date: Available online 9 March 2016
*Source:*Hearing ResearchAuthor(s): Haibo Xu, Wenliang Fan, Xueyan Zhao, Jing
Li, Wenjuan Zhang, Ping Lei, Yuan Liu, Haha Wang, Huamao Cheng, Hong ShiSudden
sensorineural hearing loss (SSNHL) is generally defined as sensorineural hearing
loss of 30 dB or greater over at least three contiguous audiometric frequencies
and within a three-day period. This hearing loss is usually unilateral and can
be associated with tinnitus and vertigo. The pathogenesis of unilateral sudden
sensorineural hearing loss is still unknown, and the alteration...περισσότερα »
ANO1 and FADD as Prognostic Markers of Head and Neck Cancer
Meta-Analyses of Microarray Datasets Identifies
ANO1 and FADD as Prognostic Markers of Head and Neck Cancer: The head and neck
squamous cell carcinoma (HNSCC) transcriptome has been profiled extensively,
nevertheless, identifying biomarkers that are clinically relevant and thereby
with translational benefit, has been a major challenge. The objective of this
study was to use a meta-analysis based approach to catalog candidate biomarkers
with high potential for clinical application in HNSCC. Data from publically
available microarray series (N = 20) profiled using Agilent (4X44K
G4112F...περισσότερα »
Socioeconomic and Other Demographic Disparities Predicting Survival among Head and Neck Cancer Patients
Socioeconomic and Other Demographic Disparities
Predicting Survival among Head and Neck Cancer Patients: Background The
Institute of Medicine (IOM) report, “Unequal Treatment,� which defines
disparities as racially based, indicates that disparities in cancer diagnosis
and treatment are less clear. While a number of studies have acknowledged cancer
disparities, they have limitations of retrospective nature, small sample sizes,
inability to control for covariates, and measurement errors.Objective The
purpose of this study was to examine disparities as predictors of survival
a...περισσότερα »
Association of VDR and CYP2R1 Polymorphisms with Mite-Sensitized Persistent Allergic Rhinitis in a Chinese Population
Association of VDR and CYP2R1 Polymorphisms with
Mite-Sensitized Persistent Allergic Rhinitis in a Chinese Population: As recent
studies have described an association between vitamin D and allergic rhinitis,
we hypothesized that vitamin D pathway-related genes may be candidate genes for
susceptibility to allergic rhinitis. Thus, we sought to evaluate whether
polymorphisms in the vitamin D receptor (*VDR*) and *CYP2R1* genes are
associated with mite-sensitized persistent allergic rhinitis (PER) in a Han
Chinese population. A hospital-based case-control study consisting of 519
patient...περισσότερα »
Abnormal Tilt Perception During Centrifugation in Patients with Vestibular Migraine
Abnormal Tilt Perception During Centrifugation in
Patients with Vestibular Migraine: AbstractVestibular migraine (VM), defined as
vestibular symptoms caused by migraine mechanisms, is very common but poorly
understood. Because dizziness is often provoked in VM patients when the
semicircular canals and otolith organs are stimulated concurrently (e.g.,
tilting the head relative to gravity), we measured tilt perception and eye
movements in patients with VM and in migraine and normal control subjects during
fixed-radius centrifugation, a paradigm that simultaneously modulates afferent
...περισσότερα »
GMP-grade α-TEA lysine salt: a 28-Day oral toxicity and toxicokinetic study with a 28-Day recovery period in Beagle dogs
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 26 δευτερόλεπτα
Alpha-tocopheryloxyacetic acid (α-TEA) is a
semi-synthetic derivative of naturally occurring vitamin E (alpha-tocopherol)
that can be delivered via an oral route. Preclinical in vitro and in vivo data
demonstr… (Source: BMC Cancer) from #Medicine-SfakianakisAlexandros via
o.lakala70 on Inoreader http://ift.tt/1QLqNrO via IFTTT Medicine by Alexandros
G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182
& 00306932607174
Human papillomavirus vaccine series completion: Qualitative information from providers within an integrated healthcare organization.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 26 δευτερόλεπτα
CONCLUSION: Interventions to improve HPV
vaccination completion rates should address both individual- and system-level
factors. Improving communication skills, encouraging a supportive medical
culture, and addressing resource issues is likely to improve vaccine adherence.
PMID: 26947497 [PubMed – as supplied by publisher] (Source: Vaccine) from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
http://ift.tt/1TsqJ5L via IFTTT Medicine by Alexandros […]
Rabies transmission risks during peripartum – Two cases and a review of the literature.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 26 δευτερόλεπτα
We report two cases of probable rabies in
near-term/at-term pregnant women in sub-Saharan Africa and Asia. One baby was
delivered by caesarean section and the other one vaginally. Both received
post-exposure prophylaxis (PEP), including RIG and vaccine and both are alive
and healthy, at 9 and 24 months, respectively. We found 14 other published cases
[…]
Quality vaccines for all people: Report of the annual general meeting of the developing countries vaccine manufacturers network, 05-07th October 2015, Bangkok, Thailand.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 26 δευτερόλεπτα
Authors: Pagliusi S, Ting CC, Khomvilai S,
DCVMN Executive, Organising Committee Group, DCVMN Executive Organising
Committee Group Abstract The Developing Countries Vaccine Manufacturers Network
(DCVMN) assembled high-profile leaders from global health organisations and
vaccine manufactures for its 16th Annual General Meeting to work towards a
common goal: providing quality vaccines for all people. Vaccines contribute
[…]
Safety of classical swine fever virus vaccine strain LOM in pregnant sows and their offspring.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 26 δευτερόλεπτα
Authors: Lim SI, Song JY, Kim J, Hyun BH,
Kim HY, Cho IS, Kim BH, Woo GH, Lee JB, An DJ Abstract The present study aimed
to evaluate the safety of the classical swine fever virus (CSFV) vaccine strain
LOM in pregnant sows. Pregnant sows with free CSFV antibody were inoculated with
a commercial LOM […]
Do selective immunisation against tuberculosis and hepatitis B reach the targeted populations? A nationwide register-based study evaluating the recommendations in the Norwegian Childhood Immunisation Programme.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 26 δευτερόλεπτα
CONCLUSIONS: Children targeted by selective
vaccination had lower coverage of the target vaccines than of vaccines in the
universal programme, indicating that selective vaccination is challenging.
Improved routines for identifying eligible children and delivering the target
vaccines are needed. Universal vaccination of all children with these vaccines
could be considered. PMID: 26947498 [PubMed – as […]
Six Ways to Reduce Your Risk of Colon Cancer
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 26 δευτερόλεπτα
Diet, weight and physical activity play a
significant role, expert says (Source: The Doctors Lounge – Oncology) from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
http://ift.tt/1QLqIV4 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos
5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &
00306932607174
Wonders & Worries: evaluation of a child centered psychosocial intervention for families who have a parent/primary caregiver with cancer
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 26 δευτερόλεπτα
ConclusionsThe results reported here suggest
that this child centered psychosocial intervention promoted positive adaptation
by actively supporting families and children while a parent/primary caregiver
coped with a cancer diagnosis. Future research is planned utilizing a randomized
controlled study design to formally evaluate the effectiveness and preventative
impact of this manualized six‐week curriculum. Copyright © 2016 […]
Impact of high self‐perceived burden to others with preferences for end‐of‐life care and its determinants for terminally ill cancer patients: a prospective cohort study
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 26 δευτερόλεπτα
ConclusionsHigh SPB was prevalent among
terminally ill cancer patients but independent of preferences for EOL care.
Cancer patients’ SPB may be lessened by adequate symptom relief to facilitate
functional independence. These strategies to ease SPB may improve the quality of
death and dying. Copyright © 2016 John Wiley & Sons, Ltd. (Source:
Psycho-Oncology) from #Medicine-SfakianakisAlexandros […]
A randomized pilot trial of a videoconference couples communication intervention for advanced GI cancer
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 26 δευτερόλεπτα
ConclusionsA couples‐based communication
intervention delivered via videoconference is feasible and acceptable in the
context of advanced cancer. Preliminary findings suggest that the intervention
shows promise in contributing to enhanced relationship functioning. Copyright ©
2016 John Wiley & Sons, Ltd. (Source: Psycho-Oncology) from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
http://ift.tt/1TsqDes via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos
5 […]
A comparative study of target ionization between hydrogen and hydrogenic ion by positronium impact
Abstract A comparative study is made between the
collision cross sections of target ionization process of hydrogen and some
hydrogenic ions by positronium impact. Calculations are performed in the
framework of Coulomb distorted eikonal approximation. Interesting qualitative
features are noted in both the scattered positronium and the ejected electron
distributions.from Biomedical Engineering via xlomafota13 on Inoreader
http://ift.tt/1R776A2via IFTTT
Moderate and Vigorous Intensity Exercise During Pregnancy and Gestational Weight Gain in Women with Gestational Diabetes
Abstract *Objectives* To estimate the associations
of moderate and vigorous intensity exercise during pregnancy with the rate of
gestational weight gain (GWG) from gestational diabetes (GDM) diagnosis to
delivery, overall and stratified by prepregnancy overweight/obesity. *Methods*
Prospective cohort study with physical activity reported shortly after the GDM
diagnosis and prepregnancy weight and post-diagnosis GWG obtained from
electronic health records (n = 1055). Multinomial logistic regression models in
the full cohort and stratified by prepregnancy overweight/obesity
estimate...περισσότερα »
Intimate Partner Violence Associated with Postpartum Depression, Regardless of Socioeconomic Status
Abstract *Objective* This study examined whether
socioeconomic status moderated the association between intimate partner violence
(IPV) and postpartum depression among a community-based sample of women.
Defining the role of poverty in the risk of postpartum depression for IPV
victims enables prioritization of health promotion efforts to maximize the
effectiveness of existing maternal-infant resources. *Methods* This
cross-sectional telephone-survey study interviewed 301 postpartum women 2 months
after delivery, screening them for IPV and depression [using Edinburgh Postnatal
Depre...περισσότερα »
The Impact of Balanced Counseling on Contraceptive Method Choice and Determinants of Long Acting and Reversible Contraceptive Continuation in Nepal
Abstract *Introduction* Long-acting reversible
contraceptives (LARCs) reduce rates of unintended pregnancies and repeat
abortion. Uptake and continuation rates of LARCs are very low in Nepal, despite
free provision from most health facilities. We sought to establish the
effectiveness of a new approach to LARC promotion in Nepal. *Methods* We
examined change in contraceptive method mix in Nepal using service data
resulting from introduction of a balanced counseling (BC) approach to family
planning (FP). All staff located at nine randomly selected FP sites were trained
and began app...περισσότερα »
Data of a willingness to pay survey for national climate change mitigation policies in Germany
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): Reinhard UehlekeThe dataset includes responses
from a contingent valuation of the national climate change mitigation policies
in Germany. The online survey was carried out in the spring of 2014. It assesses
the willingness to pay for an increase of the national CO2 reduction target by
10 percentage points, which closely represents Germany's climate change
mitigation strategy. Respondents were randomly allocated to one of the following
three question formats: The dichotomous choice referendum, the diss...περισσότερα »
Fluorescence-based thermal shift data on multidrug regulator AcrR from Salmonella enterica subsp. entrica serovar Typhimurium str. LT2
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): Babu A. Manjasetty, Andrei S. Halavaty, Chi-Hao
Luan, Jerzy Osipiuk, Rory Mulligan, Keehwan Kwon, Wayne F. Anderson, Andrzej
JoachimiakThe fluorescence-based thermal shift (FTS) data presented here include
Table S1 and Fig. S1, and are supplemental to our original research article
describing detailed structural, FTS, and fluorescence polarization analyses of
the Salmonella enterica subsp. entrica serovar Typhimurium str. LT2 multidrug
transcriptional regulator AcrR (StAcrR) (doi:10.1016/j.jsb.2016.01....περισσότερα »
Data for increase of Lymantria dispar male survival after topical application of single-stranded RING domain fragment of IAP-3 gene of its nuclear polyhedrosis virus
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): Volodymyr V. Oberemok, Kateryna V. Laikova,
Aleksei S. Zaitsev, Vladimir A. Gushchin, Oleksii A. SkorokhodThis data article
is related to the research article entitled "The RING for gypsy moth control:
topical application of fragment of its nuclear polyhedrosis virus anti-apoptosis
gene as insecticide" [1]. This article reports on significantly higher survival
of gypsy moth Lymantria dispar male individuals in response to topical
application of single-stranded DNA, based on RING (really interesting
ne...περισσότερα »
Data and the associated R code used to estimate health and economic burden of neurocysticercosis in India
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): B B Singh, M S Khatkar, J P S Gill, N K Dhand
This article contains epidemiological, demographic and other data used for
estimating health and economic burden of neurocysticercosis (NCC)-associated
active epilepsy in India [1]. Most of the data are embedded in the R-code used
for analyses so that the reader is able to replicate the results or adapt the
code to their own data. However, data used to conduct sensitivity analyses to
evaluate the effect of changing important input values such as prevalence
...περισσότερα »
Impulse noise injury prediction based on the cochlear energy
Publication date: Available online 9 March 2016
*Source:*Hearing ResearchAuthor(s): Brissi Zagadou, Philemon Chan, Kevin Ho,
David ShelleyThe current impulse noise criteria for the protection against
impulse noise injury do not incorporate an objective measure of hearing
protection. A new biomechanically-based model has been developed based on
improvement of the Auditory Hazard Assessment Algorithm for the Human (AHAAH)
using the integrated cochlear energy (ICE) as the damage risk correlate (DRC).
The model parameters have been corrected using the latest literature data. The
anomalo...περισσότερα »
Disrupted Functional Brain Connectome in Unilateral Sudden Sensorineural Hearing Loss
Publication date: Available online 9 March 2016
*Source:*Hearing ResearchAuthor(s): Haibo Xu, Wenliang Fan, Xueyan Zhao, Jing
Li, Wenjuan Zhang, Ping Lei, Yuan Liu, Haha Wang, Huamao Cheng, Hong ShiSudden
sensorineural hearing loss (SSNHL) is generally defined as sensorineural hearing
loss of 30 dB or greater over at least three contiguous audiometric frequencies
and within a three-day period. This hearing loss is usually unilateral and can
be associated with tinnitus and vertigo. The pathogenesis of unilateral sudden
sensorineural hearing loss is still unknown, and the alterations ...περισσότερα »
Impulse noise injury prediction based on the cochlear energy
Publication date: Available online 9 March 2016
*Source:*Hearing ResearchAuthor(s): Brissi Zagadou, Philemon Chan, Kevin Ho,
David ShelleyThe current impulse noise criteria for the protection against
impulse noise injury do not incorporate an objective measure of hearing
protection. A new biomechanically-based model has been developed based on
improvement of the Auditory Hazard Assessment Algorithm for the Human (AHAAH)
using the integrated cochlear energy (ICE) as the damage risk correlate (DRC).
The model parameters have been corrected using the latest literature data. The
anomalo...περισσότερα »
Disrupted Functional Brain Connectome in Unilateral Sudden Sensorineural Hearing Loss
Publication date: Available online 9 March 2016
*Source:*Hearing ResearchAuthor(s): Haibo Xu, Wenliang Fan, Xueyan Zhao, Jing
Li, Wenjuan Zhang, Ping Lei, Yuan Liu, Haha Wang, Huamao Cheng, Hong ShiSudden
sensorineural hearing loss (SSNHL) is generally defined as sensorineural hearing
loss of 30 dB or greater over at least three contiguous audiometric frequencies
and within a three-day period. This hearing loss is usually unilateral and can
be associated with tinnitus and vertigo. The pathogenesis of unilateral sudden
sensorineural hearing loss is still unknown, and the alterations ...περισσότερα »
Impulse noise injury prediction based on the cochlear energy
Publication date: Available online 9 March 2016
*Source:*Hearing ResearchAuthor(s): Brissi Zagadou, Philemon Chan, Kevin Ho,
David ShelleyThe current impulse noise criteria for the protection against
impulse noise injury do not incorporate an objective measure of hearing
protection. A new biomechanically-based model has been developed based on
improvement of the Auditory Hazard Assessment Algorithm for the Human (AHAAH)
using the integrated cochlear energy (ICE) as the damage risk correlate (DRC).
The model parameters have been corrected using the latest literature data. The
anomalo...περισσότερα »
Disrupted Functional Brain Connectome in Unilateral Sudden Sensorineural Hearing Loss
Publication date: Available online 9 March 2016
*Source:*Hearing ResearchAuthor(s): Haibo Xu, Wenliang Fan, Xueyan Zhao, Jing
Li, Wenjuan Zhang, Ping Lei, Yuan Liu, Haha Wang, Huamao Cheng, Hong ShiSudden
sensorineural hearing loss (SSNHL) is generally defined as sensorineural hearing
loss of 30 dB or greater over at least three contiguous audiometric frequencies
and within a three-day period. This hearing loss is usually unilateral and can
be associated with tinnitus and vertigo. The pathogenesis of unilateral sudden
sensorineural hearing loss is still unknown, and the alterations ...περισσότερα »
Long noncoding RNAs related to the odontogenic potential of dental mesenchymal cells in mice
Publication date: Available online 8 March 2016
*Source:*Archives of Oral BiologyAuthor(s): Yunfei Zheng, Lingfei Jia
ObjectivesThe purpose of this study is to identify the lncRNAs that are
associated with the odontogenic potential in mouse dental mesenchymal
cells.DesignThe odontogenic potential of dental mesenchymal cells was found to
be lost in the course of in vitro culture, so the lncRNA profiles were
subsequently compared between freshly-isolated and cultured dental mesenchymal
cells using RNA-sequencing. A co-expression analysis of differentially expressed
lncRNAs and coding...περισσότερα »
Impulse noise injury prediction based on the cochlear energy
Publication date: Available online 9 March 2016
*Source:*Hearing ResearchAuthor(s): Brissi Zagadou, Philemon Chan, Kevin Ho,
David ShelleyThe current impulse noise criteria for the protection against
impulse noise injury do not incorporate an objective measure of hearing
protection. A new biomechanically-based model has been developed based on
improvement of the Auditory Hazard Assessment Algorithm for the Human (AHAAH)
using the integrated cochlear energy (ICE) as the damage risk correlate (DRC).
The model parameters have been corrected using the latest literature data. The
anoma...περισσότερα »
Disrupted Functional Brain Connectome in Unilateral Sudden Sensorineural Hearing Loss
Publication date: Available online 9 March 2016
*Source:*Hearing ResearchAuthor(s): Haibo Xu, Wenliang Fan, Xueyan Zhao, Jing
Li, Wenjuan Zhang, Ping Lei, Yuan Liu, Haha Wang, Huamao Cheng, Hong ShiSudden
sensorineural hearing loss (SSNHL) is generally defined as sensorineural hearing
loss of 30 dB or greater over at least three contiguous audiometric frequencies
and within a three-day period. This hearing loss is usually unilateral and can
be associated with tinnitus and vertigo. The pathogenesis of unilateral sudden
sensorineural hearing loss is still unknown, and the alteration...περισσότερα »
Long noncoding RNAs related to the odontogenic potential of dental mesenchymal cells in mice
Publication date: Available online 8 March 2016
*Source:*Archives of Oral BiologyAuthor(s): Yunfei Zheng, Lingfei Jia
ObjectivesThe purpose of this study is to identify the lncRNAs that are
associated with the odontogenic potential in mouse dental mesenchymal
cells.DesignThe odontogenic potential of dental mesenchymal cells was found to
be lost in the course of in vitro culture, so the lncRNA profiles were
subsequently compared between freshly-isolated and cultured dental mesenchymal
cells using RNA-sequencing. A co-expression analysis of differentially expressed
lncRNAs and coding...περισσότερα »
Survival of smear-positive multidrug resistant tuberculosis patients in Witbank, South Africa: A retrospective cohort study
10.3109/23744235.2016.1153806<br>Abiola O.
Olaleyefrom Infection via ola Kala on Inoreader http://ift.tt/1R6fXvDvia IFTTT
IL-10-Expressing Th2 Cells Contribute to the Elevated Antibody Production in Rheumatoid Arthritis
Abstract Rheumatoid arthritis (RA) is a common
autoimmune disease associated with progressive disability, systemic
complications, and early death. Multiple lines of evidence have placed adaptive
immune responses in the center of RA pathogenesis. However, the functional roles
of T helper cells are insufficiently described. Here, we examined the Th2 cell
subsets and their functions in RA patients. A downregulation of IL-4+ cells in
CD4+ T cells were observed in RA patients, indicating a downregulation of Th2
cells, and these results were confirmed by using and CXCR3 and CCR6 surface
...περισσότερα »
Ti guardi allo specchio e non riconosci pi il tuo seno Masto Cod: 885
sfakianakismedicsστοORL ALLERGY
AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios
Nikolaos,Crete 72100,Greece,tel :00302841026182 &
00306932607174Πριν από 57 δευτερόλεπτα
MASTOPESSI IL LIFTING DEL SENO A PERUGIA
quot:(Può accadere che il seno perda nel tempo tonicità e che assuma una forma
più allungata -Ptosi mammaria-. Solitamente le cause sono varie tra le quali: –
gravidanza – allattamento – perdita o aumento di peso – naturale processo di
invecchiamento) Ci si trova quindi di fronte ad […]
Linking Quality of Work in Midlife to Volunteering During Retirement: a European Study
Abstract There is increasing recognition
that disadvantaged work and employment conditions over the life course,
including psychosocial stress at work, have negative long-term effects on health
at older ages. Yet, the question whether stress at work additionally influences
the likelihood of participating in voluntary work during retirement still needs
to be explored. This paper studies… Continue reading Linking Quality of Work in
Midlife to Volunteering During Retirement: a European Study
Work-Family Life Courses and Subjective Wellbeing in the MRC National Survey of Health and Development (the 1946 British birth cohort study)
Abstract Studies investigating the impact of
combining paid work and family life on wellbeing have generally used information
at one or a limited number of points in the life course, and have mainly focused
on women. This study uses multi-channel sequence analysis to characterise
work-family life courses across adulthood (ages 16–60) for more than 1500…
Continue reading Work-Family Life Courses and Subjective Wellbeing in the MRC
National Survey of Health and Development (the 1946 British birth cohort
study)
Introducing the New Book Review Section
from #ORL-AlexandrosSfakianakis via
simeraentaxei on Inoreader http://ift.tt/1p7u39r via IFTTT
Trajectories in the Prevalence of Self-Reported Illness Around Retirement
Abstract In this paper we used wave 1 (2002)
to wave 6 (2012) of the English Longitudinal Study of Ageing (ELSA) to assess
whether trajectories in the prevalence of self-reported limiting long term
illness differed before and after retirement and whether any such differences in
slope were found across socio-economic characteristics and the conditions of…
Continue reading Trajectories in the Prevalence of Self-Reported Illness Around
Retirement
Erratum to: Life Course Influences on Inequalities in Later Life: Comparative Perspectives
from #ORL-AlexandrosSfakianakis via
simeraentaxei on Inoreader http://ift.tt/1p7u2SZ via IFTTT
Support in the East Riding to Kick Smoking Habit – Yorkshire Coast Radio
Yorkshire Coast Radio Support in the East
Riding to Kick Smoking Habit Yorkshire Coast Radio While most smokers know about
the link between smoking and lung cancer, many people do not realise that
smoking is linked with not one but 16 different cancers, including cancers of
the mouth, nasal cavities, pharynx and larynx, stomach, kidney,… Continue
reading Support in the East Riding to Kick Smoking Habit – Yorkshire Coast
Radio
Revolutionary Therapies and Manipulation of Nanoparticles to Cure Cancer
The post Revolutionary Therapies and
Manipulation of Nanoparticles to Cure Cancer appeared first on Welcome to Avens.
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader
http://ift.tt/1R77Ncx via IFTTT
IJMS, Vol. 17, Pages 355: Type 2 Diabetes in Non-Alcoholic Fatty Liver Disease and Hepatitis C Virus Infection—Liver: The “Musketeer” in the Spotlight
The pathogenesis of type 2 diabetes (T2D)
involves chronic hyperinsulinemia due to systemic and hepatic insulin resistance
(IR), which if uncorrected, will lead to progressive pancreatic beta cell
failure in predisposed individuals. Non-alcoholic fatty liver disease (NAFLD)
encompasses a spectrum of fatty (simple steatosis and steatohepatitis) and
non-fatty liver changes (NASH-cirrhosis with or without hepatocellular… Continue
reading IJMS, Vol. 17, Pages 355: Type 2 Diabetes in Non-Alcoholic Fatty Liver
Disease and Hepatitis C Virus Infection—Liver: The “Musketeer” in the
Spotlight
IJMS, Vol. 17, Pages 354: Effects of Beverages on Alcohol Metabolism: Potential Health Benefits and Harmful Impacts
Nonalcoholic beverages are usually consumed
accompanying alcoholic drinks, and their effects on alcohol metabolism are
unclear in vivo. In this study, the effects of 20 nonalcoholic beverages on
alcohol metabolism and liver injury caused by alcohol were evaluated in mice.
Kunming mice were orally fed with alcohol (52%, v/v) and beverages. The
concentrations of ethanol… Continue reading IJMS, Vol. 17, Pages 354: Effects of
Beverages on Alcohol Metabolism: Potential Health Benefits and Harmful
Impacts
IJMS, Vol. 17, Pages 205: Identification of Human UDP-Glucuronosyltransferase 1A4 as the Major Isozyme Responsible for the Glucuronidation of 20(S)-Protopanaxadiol in Human Liver Microsomes
20(S)-protopanaxadiol (PPD), one of the
representative aglycones of ginsenosides, has a broad spectrum of
pharmacological activities. Although phase I metabolism has been investigated
extensively, information regarding phase II metabolism of this compound remains
to be elucidated. Here, a glucuronidated metabolite of PPD in human liver
microsomes (HLMs) and rat liver microsomes (RLMs) was unambiguously identified…
Continue reading IJMS, Vol. 17, Pages 205: Identification of Human
UDP-Glucuronosyltransferase 1A4 as the Major Isozyme Responsible for the
Glucuronidation of 20(S)-Protop...περισσότερα »
Using Behavioral Risk Factor Data as a surveillance tool to monitor the prevalence of initiation, continuation and completion of Human Papilloma Virus Vaccination in Children
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): Gia Elise Barboza, Silvia DominguezThe Human
Papilloma Virus ("HPV") is a common sexually transmitted disease that has
infected approximately 79 million men and women in the United States alone. A
vaccination is available but in order to be effective it must be received prior
to becoming sexually active and recipients must complete a three-dose sequence.
In this article we explore the predisposing, enabling and need-based factors
associated with parents' or guardians' decision to have their child
init...περισσότερα »
Atypical carcinoid and large cell neuroendocrine carcinoma of the lung: a proteomic dataset from formalin-fixed archival samples
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): Alessandro Tanca, Maria Filippa Addis,
Salvatore Pisanu, Marcello Abbondio, Daniela Pagnozzi, Albino Eccher, Guido
Rindi, Paolo Cossu-Rocca, Sergio Uzzau, Giuseppe FanciulliHere we present a
dataset generated using formalin-fixed paraffin-embedded archival samples from
two rare lung neuroendocrine tumor subtypes (namely, two atypical carcinoids,
ACs, and two large-cell neuroendocrine carcinomas, LCNECs). Samples were
subjected to a shotgun proteomics pipeline, comprising full-length protein
extraction...περισσότερα »
Understanding the occupational traveller profile towards malaria prevention enables directed health promotion and preventive practices
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 1 ώρα
2016-03-09T02-58-29Z*Source:* International Journal
of Tropical Medicine and Public HealthAna Gloria Fonseca, Susana Carvalho, Sara
Simões Dias, Joao Luis Baptista, Jorge Torgal.Aim/background: Increased
migration and expatriation to malaria endemic countries has been appointed as
contributing factor to the increasing imported malaria hospitalizations recently
observed in Portugal. This study sought to profile this traveller and understand
the knowledge, attitude and practice (KAP) towards malaria prevention as
necessary first step to improve and suit risk reduction strategies.
M...περισσότερα »
IJMS, Vol. 17, Pages 205: Identification of Human UDP-Glucuronosyltransferase 1A4 as the Major Isozyme Responsible for the Glucuronidation of 20(S)-Protopanaxadiol in Human Liver Microsomes
20(S)-protopanaxadiol (PPD), one of the
representative aglycones of ginsenosides, has a broad spectrum of
pharmacological activities. Although phase I metabolism has been investigated
extensively, information regarding phase II metabolism of this compound remains
to be elucidated. Here, a glucuronidated metabolite of PPD in human liver
microsomes (HLMs) and rat liver microsomes (RLMs) was unambiguously identified
as PPD-3-O-β-d-glucuronide by nuclear magnetic resonance spectroscopy and high
resolution mass spectrometry. The chemical inhibition and recombinant human
UDP-Glucuronosy...περισσότερα »
Marine Drugs, Vol. 14, Pages 52: Antimicrobial Action of Compounds from Marine Seaweed
Seaweed produces metabolites aiding in the
protection against different environmental stresses. These compounds show
antiviral, antiprotozoal, antifungal, and antibacterial properties. Macroalgae
can be cultured in high volumes and would represent an attractive source of
potential compounds useful for unconventional drugs able to control new diseases
or multiresistant strains of pathogenic microorganisms. The substances isolated
from green, brown and red algae showing potent antimicrobial activity belong to
polysaccharides, fatty acids, phlorotannins, pigments, lectins,
alkaloids,...περισσότερα »
Mutated Huntingtin Causes Testicular Pathology in Transgenic Minipig Boars
*Background:* Huntington's disease is induced by
CAG expansion in a single gene coding the huntingtin protein. The mutated
huntingtin (mtHtt) primarily causes degeneration of neurons in the brain, but it
also affects peripheral tissues, including testes. *Objective:* We studied sperm
and testes of transgenic boars expressing the N-terminal region of human mtHtt.
*Methods:* In this study, measures of reproductive parameters and electron
microscopy (EM) images of spermatozoa and testes of transgenic (TgHD) and
wild-type (WT) boars of F1 (24-48 months old) and F2 (12-36 months old)
gen...περισσότερα »
Anti-HMG-CoA Reductase, Antioxidant, and Anti-Inflammatory Activities of Amaranthus viridis Leaf Extract as a Potential Treatment for Hypercholesterolemia
Inflammation and oxidative stress are believed to
contribute to the pathology of several chronic diseases including
hypercholesterolemia (elevated levels of cholesterol in blood) and
atherosclerosis. HMG-CoA reductase inhibitors of plant origin are needed as
synthetic drugs, such as statins, which are known to cause adverse effects on
the liver and muscles. Amaranthus viridis (A. viridis) has been used from
ancient times for its supposedly medically beneficial properties. In the current
study, different parts of A. viridis (leaf, stem, and seed) were evaluated for
potential anti-H...περισσότερα »
Effect of Laser Acupuncture on Anthropometric Measurements and Appetite Sensations in Obese Subjects
Purpose. A patient-assessor-blinded, randomized,
sham-controlled crossover trial was performed to investigate the effectiveness
of laser acupuncture on anthropometric measurements and appetite sensation in
obese subjects. Methods. Fifty-two obese subjects were randomly assigned to
either the laser acupuncture group or the sham laser acupuncture group. Subjects
within each group received the relevant treatment three times a week for 8
weeks. After a two-week washout period, the subjects then received the treatment
of the opposite group for another 8 weeks. BMI, body fat percentage,...περισσότερα »
IJMS, Vol. 17, Pages 355: Type 2 Diabetes in Non-Alcoholic Fatty Liver Disease and Hepatitis C Virus Infection—Liver: The “Musketeer” in the Spotlight
The pathogenesis of type 2 diabetes (T2D) involves
chronic hyperinsulinemia due to systemic and hepatic insulin resistance (IR),
which if uncorrected, will lead to progressive pancreatic beta cell failure in
predisposed individuals. Non-alcoholic fatty liver disease (NAFLD) encompasses a
spectrum of fatty (simple steatosis and steatohepatitis) and non-fatty liver
changes (NASH-cirrhosis with or without hepatocellular carcinoma (HCC)) that are
commonly observed among individuals with multiple metabolic derangements,
notably including visceral obesity, IR and T2D. Hepatitis C virus ...περισσότερα »
Nanomaterials, Vol. 6, Pages 47: Copper Nanowires and Their Applications for Flexible, Transparent Conducting Films: A Review
Cu nanowires (NWs) are attracting considerable
attention as alternatives to Ag NWs for next-generation transparent conductors,
replacing indium tin oxide (ITO) and micro metal grids. Cu NWs hold great
promise for low-cost fabrication via a solution-processed route and show
preponderant optical, electrical, and mechanical properties. In this study, we
report a summary of recent advances in research on Cu NWs, covering the
optoelectronic properties, synthesis routes, deposition methods to fabricate
flexible transparent conducting films, and their potential applications. This
review ...περισσότερα »
Gels, Vol. 2, Pages 11: Effect of Granule Sizes on Acoustic Properties of Protein-Based Silica Aerogel Composites via Novel Inferential Transmission Loss Method
The acoustic properties of the silica aerogel (SA)
granules of various sizes from 0.50 to 3.35 mm, distributed into six groups of
nominal sizes and measured via a two-microphone impedance tube, are presented.
The absorption coefficients of the SA granules were evaluated at ultra- to
super-low frequency range from 50–1600 Hz. It was observed that nominal SA
granules with sizes of 1.2 mm (AG2) and 1.7 mm (AG3) displayed the best
absorption coefficients. When tested with granules filled at 5 cm depth, AG2 and
AG3 absorption coefficients peaked at 980 Hz with values of 0.86 and 0.81,
...περισσότερα »
Molecules, Vol. 21, Pages 315: Isolation, Purification and Quantification of Ginsenoside F5 and F3 Isomeric Compounds from Crude Extracts of Flower Buds of Panax ginseng
In this paper, the isolation, purification and
quantification of ginsenoside F5 and F3 isomeric compounds from crude extracts
of flower buds of Panax ginseng (CEFBPG) was investigated by reversed-phase
high-performance liquid chromatography (RP-HPLC) for the first time. The
satisfied separation at analytical scale was achieved using a Zorbax Eclipse XDB
C-18 column with a ternary mobile phase of acetonitrile–water–phosphoric acid
(28:71:1) at a flow rate of 1.0 mL/min within 40 min. UV detection was set at
203 nm. Ginsenoside F5 and F3 was 4.21 mg and 5.13 mg in 1 g flower buds
of...περισσότερα »
Sensors, Vol. 16, Pages 354: A Dynamic Instrumentation Amplifier for Low-Power and Low-Noise Biopotential Acquisition
A low-power and low-noise dynamic instrumentation
amplifier (IA) for biopotential acquisition is presented. A dynamic IA that can
reduce power consumption with a timely piecewise power-gating method, and noise
level with an alternating input and chopper stabilization technique is
fabricated with a 0.13-μm CMOS. Using the reconfigurable architecture of the IA,
various combinations of the low-noise schemes are investigated. The combination
of power gating and chopper stabilization shows a lower noise performance than
the combination of power gating and alternating input switching sc...περισσότερα »
Agronomy, Vol. 6, Pages 19: Root Exudation: The Ecological Driver of Hydrocarbon Rhizoremediation
Rhizoremediation is a bioremediation technique
whereby microbial degradation of organic contaminants occurs in the rhizosphere.
It is considered to be an effective and affordable "green technology" for
remediating soils contaminated with petroleum hydrocarbons. Root exudation of a
wide variety of compounds (organic, amino and fatty acids, carbohydrates,
vitamins, nucleotides, phenolic compounds, polysaccharides and proteins) provide
better nutrient uptake for the rhizosphere microbiome. It is thought to be one
of the predominant drivers of microbial communities in the rhizosphere
...περισσότερα »
Nanomaterials, Vol. 6, Pages 44: High Refractive Organic–Inorganic Hybrid Films Prepared by Low Water Sol-Gel and UV-Irradiation Processes
Organic-inorganic hybrid sols (Ti–O–Si precursor)
were first synthesized by the sol-gel method at low addition of water, and were
then employed to prepare a highly refractive hybrid optical film. This film was
obtained by blending the Ti–O–Si precursor with 2-phenylphenoxyethyl acrylate
(OPPEA) to perform photo-polymerization by ultraviolet (UV) irradiation. Results
show that the film transparency of poly(Ti–O–Si precursor-co-OPPEA) film is
higher than that of a pure poly(Ti–O–Si precursor) film, and that this
poly(Ti–O–Si precursor-co-OPPEA) hybrid film exhibits a high
transparenc...περισσότερα »
Actuators, Vol. 5, Pages 9: Status and Perspectives of Multiferroic Magnetoelectric Composite Materials and Applications
Multiferroic magnetoelectric (ME) composites are
attractive materials for various electrically and magnetically cross-coupled
devices. Many studies have been conducted on fundamental understanding,
fabrication processes, and applications of ME composite material systems in the
last four decades which has brought the technology closer to realization in
practical devices. In this article, we present a review of ME composite
materials and some notable potential applications based upon their properties. A
brief summary is presented on the parameters that influence the performance of
ME...περισσότερα »
Marine Drugs, Vol. 14, Pages 53: Heterotrophic Production of Omega-3 Long-Chain Polyunsaturated Fatty Acids by Trophically Converted Marine Diatom Phaeodactylum tricornutum
We have created via metabolic engineering a
heterotrophic strain of Phaeodactylum tricornutum that accumulates enhanced
levels of the high value omega-3 long chain polyunsaturated fatty acid
(LC-PUFAs) docosahexaenoic acid (DHA). This was achieved by generation of
transgenic strains in which the Δ5-elongase from Ostreococcus tauri was
co-expressed with a glucose transporter from the moss Physcomitrella patens.
This double transformant has the capacity to grow in the dark in liquid medium
supplemented with glucose and accumulate substantial levels of omega-3 LC-PUFAs.
The effects o...περισσότερα »
Partial Response to First-Line Crizotinib in an Elderly Male Patient with ROS1 Translocation-Positive Lung Cancer
We report on a 90-year-old male patient with a
*ROS1*-translocated adenocarcinoma of the lung who was treated with crizotinib
as first-line therapy. After 11 months of treatment, we noticed complete
metabolic response as measured by 18F-FDG-PET/CT scan and a partial response
according to RECIST criteria. This patient indicates that *ROS1* translocations
are not restricted to young age, female gender and low stage. Furthermore, this
case illustrates exemplarily that crizotinib therapy is effective and manageable
even as first-line treatment in elderly patients with comorbidities.
B...περισσότερα »
Immune Reactivity and Pseudoprogression or Tumor Flare in a Serially Biopsied Neuroendocrine Patient Treated with the Epigenetic Agent RRx-001
Neuroendocrine tumors (NETs) are grouped together
as a single class on the basis of histologic appearance, immunoreactivity for
the neuroendocrine markers chromogranin A and synaptophysin, and potential
secretion of hormones, neurotransmitters, neuromodulators and neuropeptides.
Nevertheless, despite these common characteristics, NETs differ widely in terms
of their natural histories: high-grade NETs are clinically aggressive and, like
small cell lung cancer, which they most closely resemble, tend to respond to
cisplatin and etoposide. In contrast, low-grade NETs, which as a rule
...περισσότερα »
Data of a willingness to pay survey for national climate change mitigation policies in Germany
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): Reinhard UehlekeThe dataset includes responses
from a contingent valuation of the national climate change mitigation policies
in Germany. The online survey was carried out in the spring of 2014. It assesses
the willingness to pay for an increase of the national CO2 reduction target by
10 percentage points, which closely represents Germany's climate change
mitigation strategy. Respondents were randomly allocated to one of the following
three question formats: The dichotomous choice referendum, the diss...περισσότερα »
Fluorescence-based thermal shift data on multidrug regulator AcrR from Salmonella enterica subsp. entrica serovar Typhimurium str. LT2
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): Babu A. Manjasetty, Andrei S. Halavaty, Chi-Hao
Luan, Jerzy Osipiuk, Rory Mulligan, Keehwan Kwon, Wayne F. Anderson, Andrzej
JoachimiakThe fluorescence-based thermal shift (FTS) data presented here include
Table S1 and Fig. S1, and are supplemental to our original research article
describing detailed structural, FTS, and fluorescence polarization analyses of
the Salmonella enterica subsp. entrica serovar Typhimurium str. LT2 multidrug
transcriptional regulator AcrR (StAcrR) (doi:10.1016/j.jsb.2016.01....περισσότερα »
Data for increase of Lymantria dispar male survival after topical application of single-stranded RING domain fragment of IAP-3 gene of its nuclear polyhedrosis virus
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): Volodymyr V. Oberemok, Kateryna V. Laikova,
Aleksei S. Zaitsev, Vladimir A. Gushchin, Oleksii A. SkorokhodThis data article
is related to the research article entitled "The RING for gypsy moth control:
topical application of fragment of its nuclear polyhedrosis virus anti-apoptosis
gene as insecticide" [1]. This article reports on significantly higher survival
of gypsy moth Lymantria dispar male individuals in response to topical
application of single-stranded DNA, based on RING (really interesting
ne...περισσότερα »
Data and the associated R code used to estimate health and economic burden of neurocysticercosis in India
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): B B Singh, M S Khatkar, J P S Gill, N K Dhand
This article contains epidemiological, demographic and other data used for
estimating health and economic burden of neurocysticercosis (NCC)-associated
active epilepsy in India [1]. Most of the data are embedded in the R-code used
for analyses so that the reader is able to replicate the results or adapt the
code to their own data. However, data used to conduct sensitivity analyses to
evaluate the effect of changing important input values such as prevalence
...περισσότερα »
Using Behavioral Risk Factor Data as a surveillance tool to monitor the prevalence of initiation, continuation and completion of Human Papilloma Virus Vaccination in Children
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): Gia Elise Barboza, Silvia DominguezThe Human
Papilloma Virus ("HPV") is a common sexually transmitted disease that has
infected approximately 79 million men and women in the United States alone. A
vaccination is available but in order to be effective it must be received prior
to becoming sexually active and recipients must complete a three-dose sequence.
In this article we explore the predisposing, enabling and need-based factors
associated with parents' or guardians' decision to have their child
init...περισσότερα »
Abnormal Tilt Perception During Centrifugation in Patients with Vestibular Migraine
Abstract Vestibular migraine (VM), defined as
vestibular symptoms caused by migraine mechanisms, is very common but poorly
understood. Because dizziness is often provoked in VM patients when the
semicircular canals and otolith organs are stimulated concurrently (e.g.,
tilting the head relative to gravity), we measured tilt perception and eye
movements in patients with VM and in migraine and normal control subjects during
fixed-radius centrifugation, a paradigm that simultaneously modulates afferent
signals from the semicircular canals and otoliths organs. Twenty-four patients
(8 i...περισσότερα »
Cadaveric Study of an Endoscopic Keyhole Middle Fossa Craniotomy Approach to the Superior Semicircular Canal.
Objective: Demonstrate that an endoscopic keyhole
approach to the middle cranial fossa is technically feasible for repair of
semicircular canal dehiscence. Study Design: Cadaveric technical
feasibility/methods development study. Setting: Tertiary care military medical
center. Patients: Three fresh cadaveric heads (six sides). Intervention(s):
Endoscopic minimally invasive approach to the middle cranial fossa using the
Medtronic Fusion Guidance system. Main Outcome Measure(s): Ability to identify
the surgical landmarks of the middle cranial fossa and successfully identify and
instrum...περισσότερα »
Quantitative Analysis of Psychiatric Disorders in Intractable Peripheral Vertiginous Patients: A Prospective Study.
Objective: To investigate the correlation between
psychological disorder and vestibular dysfunction in patients suffering from
intractable peripheral vertigo. Study Design: Prospective study. Setting:
In-patients in a university hospital. Methods: Prospective design of 26
intractable peripheral vertiginous patients with peripheral vestibular
dysfunction and 20 controls recruited from the EENT hospital. Hospital Anxiety
and Depression scale, Self-rating Anxiety scale, Self-rating Depression scale,
Symptom Checklist-90 were used in this study. All vertigo patients received
intratympan...περισσότερα »
Histopathologic Diagnosis of Multifactorial Alopecia
Abstract Establishing a definitive diagnosis for
any form of alopecia can be challenging. Adding to the diagnostic complexity is
the fact that many patients have more than one form of alopecia contributing to
their hair loss. We conducted a review of 1360 consecutive scalp biopsy
specimens submitted for the evaluation of scalp hair loss over a 16-month
period, demonstrating that 12.5% of cases had a combination of diagnoses
(multifactorial alopecia) accounting for their hair loss. An approach to the
histopathologic diagnosis of multifactorial alopecia, particularly multiple
forms ...περισσότερα »
Revisiting histopathologic findings in Goltz syndrome
Abstract Goltz syndrome (focal dermal hypoplasia)
is an X-linked dominant disorder that is classically associated with yellowish
papules representing fat herniation (superficial adipocytes). We report a series
of 3 cases, with clinicopathologic correlation of biopsies from Blaschkoid
streaks. A range of histopathologic features, including some underreported
findings (increased papillary dermal blood vessels, decreased thickness of the
dermis, and adipocytes high in the dermis), are reproducible and can strongly
point to the correct diagnosis of Goltz syndrome.from Anatomy Pathol...περισσότερα »
Clear Cell Atypical Fibroxanthoma: a Case Report and Review of the Literature
ABSTRACT Atypical fibroxanthoma (AFX) is a group of
cutaneous tumors characterized by a population of fusiform, epithelioid, and
pleomorphic cells. Clinically, AFX is commonly found on the head and neck of
older adults as a solitary ulcerated nodule. Clear cell atypical fibroxanthoma
is a very rare variant of AFX, with only thirteen cases reported to date. The
differential diagnoses often include dermal neoplasms composed of clear cells,
such as squamous cell carcinoma, basal cell carcinoma, metastatic renal cell
carcinoma, and balloon cell malignant melanoma. These diagnoses can
b...περισσότερα »
Skin involvement as the first manifestation of breast implant-associated anaplastic large cell lymphoma
Abstract Breast implant–associated large cell
anaplastic lymphoma (ALCL) is a newly described clinical and pathologic entity
that typically presents as seroma in the fibrous scar around the implant. Less
frequently, it presents as a solid peri-implant mass, and there have been no
reports to date of cutaneous lesions as the presenting manifestation.We report
the case of a 56-year-old woman with a history of bilateral breast
reconstruction following breast cancer of the right breast who consulted with
several papules on the right breast suggestive of metastasis. Histopathology
show...περισσότερα »
Polymorphous sweat gland carcinoma: a report of two cases
ABSTRACT Polymorphous sweat gland carcinoma (PSGC)
is a rare adnexal neoplasm with characteristic variegated histopathologic
findings and low-grade clinical behavior. First described in 1994, only eleven
cases have been reported in the literature. It is named for the multiplicity of
architectural patterns that may be present: solid, tubular, trabecular,
pseudopapillary and cylindromatous. Due to the multiple architectural patterns,
the differential diagnosis is broad, including metastatic adenocarcinoma and
other adnexal neoplasms with ductular differentiation. We present two new
...περισσότερα »
Pigmented Desmoplastic trichilemmoma
from Anatomy Pathology via ola Kala on Inoreader
http://ift.tt/1W8eBVIvia IFTTT
Postirradiation pseudosclerodermatous panniculitis with involvement of breast parenchyma: A dramatic example of a rare entity and a pitfall in diagnosis
Abstract Postirradiation pseudosclerodermatous
panniculitis is a rare complication of external beam radiotherapy. This
inflammatory process typically presents as an erythematous indurated plaque in a
previously irradiated region of skin. To date, 13 cases have been reported
worldwide. We present a case of a 70 year-old female who received breast
irradiation following conservation surgery for invasive breast carcinoma. In her
third year of follow-up she developed an enlarging mass, involving the subcutis
and underlying breast tissue, associated with mammographically-detected coarse
...περισσότερα »
Histopathology of keratotic papules of the limbs in frontal fibrosing alopecia
Abstract Frontal fibrosing alopecia (FFA) is a
scarring type of alopecia that presents clinically as progressive frontotemporal
hairline regression and eyebrow loss, mainly in postmenopausal women. An
additional common finding is keratotic papules on the face or (less commonly) on
the trunk and extremities. The histopathology of the facial keratotic papules
associated with FFA is the same as that of lichen planopilaris. There are very
few FFA cases with biopsies from extrafacial sites and no cases of
folliculocentric keratotic papules with biopsies from extrafacial sites. In the
cu...περισσότερα »
Methotrexate-associated EBV-positive vasculitis in the skin: a report of two cases simulating rheumatoid vasculitis
Abstract Rheumatoid vasculitis (RV) is one of the
most serious extra-articular complications of rheumatoid arthritis (RA),
generally treated with a high dose of immunosuppressive drugs. Recently, we
encountered two cases of ulcerative vasculitis in methotrexate (MTX)-prescribed
RA patients, which simulated RV; however, Epstein-Barr virus (EBV)-encoded RNA
*in situ* hybridization on their skin biopsies revealed many EBV-positive
lymphocytes (over 50 cells/high-power field) within the vessel walls and
perivascular stroma, which led us to the diagnosis of EBV-related vasculitis
instea...περισσότερα »
Spindle B-cell lymphoma: a rare variant of follicle center lymphoma
Abstract Primary cutaneous follicle center lymphoma
(PCFCL) is a common subtype of primary cutaneous B-cell lymphoma (PCBCL). The
prognosis of this subtype is favorable and recurrence is observed in up to 50%
of patients. The dissemination to lymph nodes or internal organs is rare. In
this study, two cases of rare variant of PCFCL are reported. Both cases
presented with multiple erythematous nodules , plaques and some annular
configurations . Histopathological examination revealed dermal lymphocytic
infiltrates consisting of admixed centrocytes and centroblasts. Interestingly,
spi...περισσότερα »
Eruptive Angiokeratomas and Porokeratosis in the setting of Sclerodermatous Graft-Versus-Host Disease
Abstract Porokeratosis and angiokeratomas are both
seen in the setting of chronic graft-versus-host-disease (GVHD), but rarely
occur together. We present a case of a patient with lichen planus-like (LPL) and
sclerodermatous chronic GVHD manifesting after allogeneic bone marrow transplant
with concomitant eruptive angiokeratomas and porokeratosis.from Anatomy
Pathology via ola Kala on Inoreader http://ift.tt/1US31Q7via IFTTT
An unusual presentation of Dermatofibrosarcoma Protuberans with pleomorphic sarcomatous transformation: potential pitfall and diagnostic strategy
Abstract Dermatofibrosarcoma protuberans (DFSP) is
a low grade, superficial sarcoma characterized by a proliferation of
monomorphous, spindle cells arranged in a storiform pattern and infiltrating the
subcutaneous tissue. The tumor is typically CD34 positive, and shows the
characteristic COL1A1-PDGFB fusion gene, detectable either by FISH and PCR. We
describe a case of DFSP with a focus of peculiar pleomorphic sarcomatous
transformation. The focus constituted the entire bioptic tissue that was
initially excised, raising considerable diagnostic problems for pathologist. The
use of F...περισσότερα »
HLA-DMB in Amerindians: specific linkage of DMB∗01:03:01/DRB1 alleles.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
CONCLUSION: The specific Amerindian HLA-DMB
allele frequencies and their linkage disequilibrium with other MHC alleles may
be crucial to determine HLA-DMB World wide variation, evolution and specific
linkage to disease in Amerindians and other populations. PMID: 26944519 [PubMed
– as supplied by publisher] (Source: Human Immunology) from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
http://ift.tt/1YvXcaI via IFTTT […]
Mutated Huntingtin Causes Testicular Pathology in Transgenic Minipig Boars
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
Background: Huntington’s disease is induced
by CAG expansion in a single gene coding the huntingtin protein. The mutated
huntingtin (mtHtt) primarily causes degeneration of neurons in the brain, but it
also affects peripheral tissues, including testes. Objective: We studied sperm
and testes of transgenic boars expressing the N-terminal region of human mtHtt.
Methods: In this […]
5-Methylcytosine-Rich Heterochromatin in the Indian Muntjac
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
Two 5-methylcytosine (5-MeC)-rich
heterochromatic regions were demonstrated in metaphase chromosomes of the Indian
muntjac by indirect immunofluorescence using a monoclonal anti-5-MeC antibody.
The metaphases were obtained from diploid and triploid cell lines. A major
region is located in the ‘neck’ of the 3;X fusion chromosome and can be detected
after denaturation of the chromosomal DNA […]
Atypical carcinoid and large cell neuroendocrine carcinoma of the lung: a proteomic dataset from formalin-fixed archival samples
Publication date: Available online 9 March 2016
*Source:*Data in BriefAuthor(s): Alessandro Tanca, Maria Filippa Addis,
Salvatore Pisanu, Marcello Abbondio, Daniela Pagnozzi, Albino Eccher, Guido
Rindi, Paolo Cossu-Rocca, Sergio Uzzau, Giuseppe FanciulliHere we present a
dataset generated using formalin-fixed paraffin-embedded archival samples from
two rare lung neuroendocrine tumor subtypes (namely, two atypical carcinoids,
ACs, and two large-cell neuroendocrine carcinomas, LCNECs). Samples were
subjected to a shotgun proteomics pipeline, comprising full-length protein
extraction...περισσότερα »
Histopathologic Diagnosis of Multifactorial Alopecia
Abstract Establishing a definitive diagnosis for
any form of alopecia can be challenging. Adding to the diagnostic complexity is
the fact that many patients have more than one form of alopecia contributing to
their hair loss. We conducted a review of 1360 consecutive scalp biopsy
specimens submitted for the evaluation of scalp hair loss over a 16-month
period, demonstrating that 12.5% of cases had a combination of diagnoses
(multifactorial alopecia) accounting for their hair loss. An approach to the
histopathologic diagnosis of multifactorial alopecia, particularly multiple
forms ...περισσότερα »
Revisiting histopathologic findings in Goltz syndrome
Abstract Goltz syndrome (focal dermal hypoplasia)
is an X-linked dominant disorder that is classically associated with yellowish
papules representing fat herniation (superficial adipocytes). We report a series
of 3 cases, with clinicopathologic correlation of biopsies from Blaschkoid
streaks. A range of histopathologic features, including some underreported
findings (increased papillary dermal blood vessels, decreased thickness of the
dermis, and adipocytes high in the dermis), are reproducible and can strongly
point to the correct diagnosis of Goltz syndrome.from #Dermatology v...περισσότερα »
Clear Cell Atypical Fibroxanthoma: a Case Report and Review of the Literature
ABSTRACT Atypical fibroxanthoma (AFX) is a group of
cutaneous tumors characterized by a population of fusiform, epithelioid, and
pleomorphic cells. Clinically, AFX is commonly found on the head and neck of
older adults as a solitary ulcerated nodule. Clear cell atypical fibroxanthoma
is a very rare variant of AFX, with only thirteen cases reported to date. The
differential diagnoses often include dermal neoplasms composed of clear cells,
such as squamous cell carcinoma, basal cell carcinoma, metastatic renal cell
carcinoma, and balloon cell malignant melanoma. These diagnoses can
b...περισσότερα »
Skin involvement as the first manifestation of breast implant-associated anaplastic large cell lymphoma
Abstract Breast implant–associated large cell
anaplastic lymphoma (ALCL) is a newly described clinical and pathologic entity
that typically presents as seroma in the fibrous scar around the implant. Less
frequently, it presents as a solid peri-implant mass, and there have been no
reports to date of cutaneous lesions as the presenting manifestation.We report
the case of a 56-year-old woman with a history of bilateral breast
reconstruction following breast cancer of the right breast who consulted with
several papules on the right breast suggestive of metastasis. Histopathology
show...περισσότερα »
Polymorphous sweat gland carcinoma: a report of two cases
ABSTRACT Polymorphous sweat gland carcinoma (PSGC)
is a rare adnexal neoplasm with characteristic variegated histopathologic
findings and low-grade clinical behavior. First described in 1994, only eleven
cases have been reported in the literature. It is named for the multiplicity of
architectural patterns that may be present: solid, tubular, trabecular,
pseudopapillary and cylindromatous. Due to the multiple architectural patterns,
the differential diagnosis is broad, including metastatic adenocarcinoma and
other adnexal neoplasms with ductular differentiation. We present two new
...περισσότερα »
Pigmented Desmoplastic trichilemmoma
from #Dermatology via alexandrossfakianakis on
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Postirradiation pseudosclerodermatous panniculitis with involvement of breast parenchyma: A dramatic example of a rare entity and a pitfall in diagnosis
Abstract Postirradiation pseudosclerodermatous
panniculitis is a rare complication of external beam radiotherapy. This
inflammatory process typically presents as an erythematous indurated plaque in a
previously irradiated region of skin. To date, 13 cases have been reported
worldwide. We present a case of a 70 year-old female who received breast
irradiation following conservation surgery for invasive breast carcinoma. In her
third year of follow-up she developed an enlarging mass, involving the subcutis
and underlying breast tissue, associated with mammographically-detected coarse
...περισσότερα »
Histopathology of keratotic papules of the limbs in frontal fibrosing alopecia
Abstract Frontal fibrosing alopecia (FFA) is a
scarring type of alopecia that presents clinically as progressive frontotemporal
hairline regression and eyebrow loss, mainly in postmenopausal women. An
additional common finding is keratotic papules on the face or (less commonly) on
the trunk and extremities. The histopathology of the facial keratotic papules
associated with FFA is the same as that of lichen planopilaris. There are very
few FFA cases with biopsies from extrafacial sites and no cases of
folliculocentric keratotic papules with biopsies from extrafacial sites. In the
cu...περισσότερα »
Methotrexate-associated EBV-positive vasculitis in the skin: a report of two cases simulating rheumatoid vasculitis
Abstract Rheumatoid vasculitis (RV) is one of the
most serious extra-articular complications of rheumatoid arthritis (RA),
generally treated with a high dose of immunosuppressive drugs. Recently, we
encountered two cases of ulcerative vasculitis in methotrexate (MTX)-prescribed
RA patients, which simulated RV; however, Epstein-Barr virus (EBV)-encoded RNA
*in situ* hybridization on their skin biopsies revealed many EBV-positive
lymphocytes (over 50 cells/high-power field) within the vessel walls and
perivascular stroma, which led us to the diagnosis of EBV-related vasculitis
instea...περισσότερα »
Spindle B-cell lymphoma: a rare variant of follicle center lymphoma
Abstract Primary cutaneous follicle center lymphoma
(PCFCL) is a common subtype of primary cutaneous B-cell lymphoma (PCBCL). The
prognosis of this subtype is favorable and recurrence is observed in up to 50%
of patients. The dissemination to lymph nodes or internal organs is rare. In
this study, two cases of rare variant of PCFCL are reported. Both cases
presented with multiple erythematous nodules , plaques and some annular
configurations . Histopathological examination revealed dermal lymphocytic
infiltrates consisting of admixed centrocytes and centroblasts. Interestingly,
spi...περισσότερα »
Eruptive Angiokeratomas and Porokeratosis in the setting of Sclerodermatous Graft-Versus-Host Disease
Abstract Porokeratosis and angiokeratomas are both
seen in the setting of chronic graft-versus-host-disease (GVHD), but rarely
occur together. We present a case of a patient with lichen planus-like (LPL) and
sclerodermatous chronic GVHD manifesting after allogeneic bone marrow transplant
with concomitant eruptive angiokeratomas and porokeratosis.from #Dermatology via
alexandrossfakianakis on Inoreader http://ift.tt/1US31Q7via IFTTT
An unusual presentation of Dermatofibrosarcoma Protuberans with pleomorphic sarcomatous transformation: potential pitfall and diagnostic strategy
Abstract Dermatofibrosarcoma protuberans (DFSP) is
a low grade, superficial sarcoma characterized by a proliferation of
monomorphous, spindle cells arranged in a storiform pattern and infiltrating the
subcutaneous tissue. The tumor is typically CD34 positive, and shows the
characteristic COL1A1-PDGFB fusion gene, detectable either by FISH and PCR. We
describe a case of DFSP with a focus of peculiar pleomorphic sarcomatous
transformation. The focus constituted the entire bioptic tissue that was
initially excised, raising considerable diagnostic problems for pathologist. The
use of F...περισσότερα »
Abnormal Tilt Perception During Centrifugation in Patients with Vestibular Migraine
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Vestibular migraine (VM), defined
as vestibular symptoms caused by migraine mechanisms, is very common but poorly
understood. Because dizziness is often provoked in VM patients when the
semicircular canals and otolith organs are stimulated concurrently (e.g.,
tilting the head relative to gravity), we measured tilt perception and eye
movements in patients with VM and […]
ARAS: an automated radioactivity aliquoting system for dispensing solutions containing positron-emitting radioisotopes
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Background Automated protocols for
measuring and dispensing solutions containing radioisotopes are essential not
only for providing a safe environment for radiation workers but also to ensure
accuracy of dispensed radioactivity and an efficient workflow. For this purpose,
we have designed ARAS, an automated radioactivity aliquoting system for
dispensing solutions containing positron-emitting radioisotopes with particular
[…]
A call for specific geriatric data on cervical cancers
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
Future Oncology Ahead of Print. from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
http://ift.tt/1LQId9E via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos
5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &
00306932607174
Pharmacokinetics of Immediate and Sustained Release Cephalexin Administered by Different Routes to Llamas (Lama glama)
We investigate the pharmacokinetics of two
different cephalexin formulations administered to llamas by the intravenous
(IV), intramuscular (IM), and subcutaneous (SC) routes, the minimum inhibitory
concentration (MIC) of cephalexin against some Escherichia coli and
staphylococci isolated from llamas, and we apply the PK/PD modelling approach,
so that effective dosage recommendations for this species could be made. Six
llamas received immediate (10 mg/kg, IV, IM, and SC) and sustained (8 mg/kg IM,
SC) release cephalexin. Pharmacokinetic parameters were calculated by
noncompartmenta...περισσότερα »
Clear Cell Atypical Fibroxanthoma: a Case Report and Review of the Literature
ABSTRACT Atypical fibroxanthoma (AFX) is a group of
cutaneous tumors characterized by a population of fusiform, epithelioid, and
pleomorphic cells. Clinically, AFX is commonly found on the head and neck of
older adults as a solitary ulcerated nodule. Clear cell atypical fibroxanthoma
is a very rare variant of AFX, with only thirteen cases reported to date. The
differential diagnoses often include dermal neoplasms composed of clear cells,
such as squamous cell carcinoma, basal cell carcinoma, metastatic renal cell
carcinoma, and balloon cell malignant melanoma. These diagnoses can
b...περισσότερα »
Clear Cell Atypical Fibroxanthoma: a Case Report and Review of the Literature
ABSTRACT Atypical fibroxanthoma (AFX) is a group of
cutaneous tumors characterized by a population of fusiform, epithelioid, and
pleomorphic cells. Clinically, AFX is commonly found on the head and neck of
older adults as a solitary ulcerated nodule. Clear cell atypical fibroxanthoma
is a very rare variant of AFX, with only thirteen cases reported to date. The
differential diagnoses often include dermal neoplasms composed of clear cells,
such as squamous cell carcinoma, basal cell carcinoma, metastatic renal cell
carcinoma, and balloon cell malignant melanoma. These diagnoses can
b...περισσότερα »
Injury grade is a predictor of aortic-related death among patients with blunt thoracic aortic injury
Journal of Vascular Surgeryfrom Emergency Medicine
via ola Kala on Inoreader http://ift.tt/1SySdWkvia IFTTT
Cerebral oximetry and capnography in excessive hyperventilated pediatric increase ICP patients: case series demonstrating the physiologic premise, excessive hyperventilation leads to decreased regional cerebral blood flow and oxygenation
The American Journal of Emergency Medicinefrom
Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QLcovDvia IFTTT
Efficacy of simulation application SimMon for emergency response training
The American Journal of Emergency Medicinefrom
Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SySbxNvia IFTTT
Knowledge about Hepatitis C Virus Infection and Acceptability of Testing in the 1945–1965 Birth Cohort (Baby Boomers) Presenting to a Large Urban Emergency Department: A Pilot Study
The Journal of Emergency Medicinefrom Emergency
Medicine via ola Kala on Inoreader http://ift.tt/1QLcofavia IFTTT
Orbital compartment syndrome due to acute hemorrhage within an orbital lymphatic malformation: emergency treatment with percutaneous sclerotherapy
Journal of Vascular and Interventional Radiology
from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SySdFKvia IFTTT
Clinical effectiveness, quality of life and cost-effectiveness of Flaminal® versus Flamazine® in the treatment of partial thickness burns: study protocol for a randomized controlled trial
Trialsfrom Emergency Medicine via ola Kala on
Inoreader http://ift.tt/1QLcoeZvia IFTTT
A quick and easy delirium assessment for non-physician research personnel
The American Journal of Emergency Medicinefrom
Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SySdpovia IFTTT
Postoperative negative pressure therapy significantly reduces flap complications in distally based peroneus brevis flaps: Experiences from 74 cases
Injuryfrom Emergency Medicine via ola Kala on
Inoreader http://ift.tt/1QLcmUHvia IFTTT
The impact of transfer on pediatric trauma outcomes
Journal of Pediatric Surgeryfrom Emergency Medicine
via ola Kala on Inoreader http://ift.tt/1SySb0Dvia IFTTT
Prevalence of marijuana use disorders in the United States between 2001-2001 and 2012-2013
The Journal of Emergency Medicinefrom Emergency
Medicine via ola Kala on Inoreader http://ift.tt/1QLcnIevia IFTTT
Outcomes of basic versus advanced life support for out-of-hospital medical emergencies
The Journal of Emergency Medicinefrom Emergency
Medicine via ola Kala on Inoreader http://ift.tt/1SySaKhvia IFTTT
Improved identification of sternal injuries with multi-detector computed tomography (MDCT): sagittal reconstructions
Clinical Imagingfrom Emergency Medicine via ola
Kala on Inoreader http://ift.tt/1QLcmDZvia IFTTT
Comparison of the VivaSight™ single lumen endotracheal tube and the Macintosh laryngoscope for emergency intubation by experienced paramedics in a standardized airway manikin with restricted access. A randomized, crossover trial
The American Journal of Emergency Medicinefrom
Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SyScSgvia IFTTT
Progesterone for traumatic brain injury: a meta-narrative review of randomized controlled trials
World Neurosurgeryfrom Emergency Medicine via ola
Kala on Inoreader http://ift.tt/1QLcmDVvia IFTTT
Analgesic adherence in recently discharged trauma patients: An integrative literature review
Pain Management Nursingfrom Emergency Medicine via
ola Kala on Inoreader http://ift.tt/1SyScBMvia IFTTT
The impact of a preauthorization policy on the after-hours utilization of emergency department computed tomography imaging
Academic Radiologyfrom Emergency Medicine via ola
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Early trends among seven recommendations from the choosing wisely campaign
The Journal of Emergency Medicinefrom Emergency
Medicine via ola Kala on Inoreader http://ift.tt/1SyS9Ggvia IFTTT
Clinical Features and Treatment Modes of Mandibular Fracture at the Department of Oral and Maxillofacial Surgery, Shimane University Hospital, Japan
Background The number of elderly patients
with maxillofacial trauma is rapidly increasing due to active lifestyles and
longevity. Shimane prefecture has the fastest growing proportion of elderly
individuals in Japan. The aim of this study was to reveal the distinctive
features and treatment modes of mandibular fracture treatment mode in patients
requiring hospitalization at the… Continue reading Clinical Features and
Treatment Modes of Mandibular Fracture at the Department of Oral and
Maxillofacial Surgery, Shimane University Hospital, Japan
Masthead
Publication date: April 2016
Source:Translational Research, Volume 170 from #ORL-AlexandrosSfakianakis via
simeraentaxei on Inoreader http://ift.tt/1UdIwN6 via IFTTT
Editorial Advisory Board
Publication date: April 2016
Source:Translational Research, Volume 170 from #ORL-AlexandrosSfakianakis via
simeraentaxei on Inoreader http://ift.tt/1RR0keO via IFTTT
Prevalence of Oral and Maxillofacial Trauma in Elders Admitted to a Reference Hospital in Northeastern Brazil
Objective To know the prevalence and
etiology of oral and maxillofacial trauma in elders. Methods Analytical
quantitative cross-sectional study conducted at a public trauma hospital located
in Fortaleza-Ceará, Brazil. The study population comprised patients with trauma
who were hospitalized from April to August 2014. Of these patients, patients
with oral and maxillofacial trauma were chosen… Continue reading Prevalence of
Oral and Maxillofacial Trauma in Elders Admitted to a Reference Hospital in
Northeastern Brazil
S-Nitrosoglutathione Accelerates Recovery from 5-Fluorouracil-Induced Oral Mucositis
Introduction Mucositis induced by
anti-neoplastic drugs is an important, dose-limiting and costly side-effect of
cancer therapy. Aim To evaluate the effect of the topical application of
S-nitrosoglutathione (GSNO), a nitric oxide donor, on 5-fluorouracil
(5-FU)-induced oral mucositis in hamsters. Materials and Methods Oral mucositis
was induced in male hamsters by two intraperitoneal administrations of 5-FU…
Continue reading S-Nitrosoglutathione Accelerates Recovery from
5-Fluorouracil-Induced Oral Mucositis
Author Guidelines
Publication date: April 2016
Source:Translational Research, Volume 170 from #ORL-AlexandrosSfakianakis via
simeraentaxei on Inoreader http://ift.tt/1UdIwws via IFTTT
MicroRNA 25, microRNA 145, and microRNA 210 as biomarkers for predicting the efficacy of maintenance treatment with pemetrexed in lung adenocarcinoma patients who are negative for epidermal growth factor receptor mutations or anaplastic lymphoma kinase translocations
Publication date: April 2016
Source:Translational Research, Volume 170 Author(s): Sheng-Bin Shi, Meng Wang,
Jing Tian, Rui Li, Chun-Xiao Chang, Jie-Lin Qi This study was conducted to
evaluate microRNAs (miRNAs) as biomarkers for use in predicting the efficacy of
maintenance therapy with pemetrexed in patients with stage IIIb or IV lung
adenocarcinoma and who had already… Continue reading MicroRNA 25, microRNA 145,
and microRNA 210 as biomarkers for predicting the efficacy of maintenance
treatment with pemetrexed in lung adenocarcinoma patients who are negative for
epidermal growth f...περισσότερα »
IJERPH, Vol. 13, Pages 306: Global Evidence on the Association between POS Advertising Bans and Youth Smoking Participation
Background: Point-of-sale (POS) tobacco
advertising has been linked to youth smoking susceptibility and experimental
smoking. However, there is limited evidence of the association between POS
advertising bans and youth smoking participation. This study aims to examine how
such bans are associated with current smoking, daily smoking, and regular
smoking (≥1 cigarettes per day) participation among… Continue reading IJERPH,
Vol. 13, Pages 306: Global Evidence on the Association between POS Advertising
Bans and Youth Smoking Participation
Precision-cut human kidney slices as a model to elucidate the process of renal fibrosis
Publication date: April 2016
Source:Translational Research, Volume 170 Author(s): Elisabeth G.D. Stribos,
Theerut Luangmonkong, Anna M. Leliveld, Igle J. de Jong, Willem J. van Son,
Jan-Luuk Hillebrands, Marc A. Seelen, Harry van Goor, Peter Olinga, Henricus
A.M. Mutsaers Chronic kidney disease is a major health concern, and experimental
models bridging the gap between animal studies… Continue reading Precision-cut
human kidney slices as a model to elucidate the process of renal
fibrosis
ARAS: an automated radioactivity aliquoting system for dispensing solutions containing positron-emitting radioisotopes
Abstract Background Automated protocols for
measuring and dispensing solutions containing radioisotopes are essential not
only for providing a safe environment for radiation workers but also to ensure
accuracy of dispensed radioactivity and an efficient workflow. For this purpose,
we have designed ARAS, an automated radioactivity aliquoting system for
dispensing solutions containing positron-emitting radioisotopes with particular…
Continue reading ARAS: an automated radioactivity aliquoting system for
dispensing solutions containing positron-emitting radioisotopes
Eye lens dosimetry in anesthesiology: a prospective study
Abstract The eye lens is one of the most sensitive
organs for radiation injury and exposure might lead to radiation induced
cataract. Eye lens dosimetry in anesthesiology has been published in few
clinical trials and an active debate about the causality of radiation induced
cataract is still ongoing. Recently, the International Commission on
Radiological Protection (ICRP) recommended a reduction in the annual dose limit
for occupational exposure for the lens of the eye from 150 to 20 mSv, averaged
over a period of 5 years, with the dose in a single year not exceeding 50 mSv.
This ...περισσότερα »
The metabolic vascular syndrome – guide to an individualized treatment
Abstract In ancient Greek medicine the concept of a
distinct syndrome (going together) was used to label 'a group of signs and
symptoms' that occur together and 'characterize a particular abnormality and
condition'. The (dys)metabolic syndrome is a common cluster of five pre-morbid
metabolic-vascular risk factors or diseases associated with increased
cardiovascular morbidity, fatty liver disease and risk of cancer. The risk for
major complications such as cardiovascular diseases, NASH and some cancers
develops along a continuum of risk factors into clinical diseases. Therefore we
...περισσότερα »
SC: Any proof that smoking causes cancer? – Times of India
[image:
images?q=tbn:ANd9GcQeLFP0NKRrvVgJSeXXwoudqd-459fsLEXFj3ryjVe0NlT1S-RrdgXYEXHyqBPEOzTGAuiw5Rto]
The Indian Express *SC: Any proof that smoking causes cancer?**Times of India*
And there are people who are smokers yet have lived healthy till the end," the
bench said before seeking the Centre's response to the petition filed by an
Allahabad-based advocate addicted to 'gutka' and smoking, who is battling
*tongue* and mouth *cancer* *…*Decline in tobacco users in India: Healthy sign
but smoke signals still worryingThe Indian ExpressSC queries tobacco's *cancer*
linkCalcutta Teleg...περισσότερα »
When does chronic migraine strike? A clinical comparison of migraine according to the headache days suffered per month
IntroductionAccording to the IHCD-3β
classification, chronic migraine (CM) is headache occurring on 15 or more
days/month. Episodic migraine (EM) can be divided into low frequency (LFEM) and
high frequency (HFEM) depending on the headache days suffered per month.Methods
We performed a clinical comparison of migraine characteristics according to
monthly headache days suffered. Patients were divided into three groups: LFEM
(1–9 headache days/month), HFEM (10–14 headache days/month) and CM (≥15 headache
days/month).ResultsThe analysis included 1109 patients. Previously
reporte...περισσότερα »
IJERPH, Vol. 13, Pages 302: Meta-Analysis of Cardiac Mortality in Three Cohorts of Carbon Black Production Workers
Epidemiological studies have demonstrated
associations between airborne environmental particle exposure and cardiac
disease and mortality; however, few have examined such effects from poorly
soluble particles of low toxicity such as manufactured carbon black (CB)
particles in the work place. We combined standardised mortality ratio (SMR) and
Cox proportional hazards results from cohort studies of US, UK and German CB
production workers. Under a common protocol, we analysed mortality from all
causes, heart disease (HD), ischemic heart disease (IHD) and acute myocardial
infarction (...περισσότερα »
Nanomaterials, Vol. 6, Pages 46: Formation and Controlled Drug Release Using a Three-Component Supramolecular Hydrogel for Anti-Schistosoma Japonicum Cercariae
A novel three-component supramolecular hydrogel
based on riboflavin, melamine and amino acid derivatives were constructed for
controlled release of pesticides, Niclosamide derivatives. The formation of
hydrogel may be attributed to self-assemble via hydrogen bonding and π–π
interaction, which have been researched via scanning electron microscopy (SEM)
and Fourier transform infrared (FT-IR) spectra. The rheological experiments
showed that the hydrogel materials and drug-loaded hydrogel all demonstrated
good mechanical strength and high stability. Further experimental results
indica...περισσότερα »
Mitteilungen der GfH
from #Medicine-SfakianakisAlexandros via o.lakala70
on Inoreader http://ift.tt/1p7gOWxvia IFTTT Medicine by Alexandros
G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182
& 00306932607174from #Med Blogs by Alexandros G.Sfakianakis via
Alexandros G.Sfakianakis on Inoreader http://ift.tt/1pwSCNRvia IFTTTfrom #Med
Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader
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A call for specific geriatric data on cervical cancers
Future Oncology Ahead of Print.from Cancer via ola
Kala on Inoreader http://ift.tt/1URWu7Mvia IFTTT
Insight into the molecular basis of Schistosoma haematobium -induced bladder cancer through urine proteomics
Abstract Infection due to *Schistosoma haematobium*
is carcinogenic. However, the cellular and molecular mechanisms underlying
urogenital schistosomiasis (UGS)-induced carcinogenesis have not been well
defined. Conceptually, early molecular detection of this phenomenon, through
non-invasive procedures, seems feasible and is desirable. Previous analysis of
urine collected during UGS suggests that estrogen metabolites, including
depurinating adducts, may be useful for this purpose. Here, a new direction was
pursued: the identification of molecular pathways and potential biomarkers
i...περισσότερα »
High incidence of TERT mutation in brain tumor cell lines
Abstract *TERT* promoter gene mutations are highly
recurrent in malignant glioma. However, little information exists regarding
their presence in experimental brain tumor models. To better characterize
systems in which *TERT* mutation studies could be appropriately modeled
experimentally, the *TERT* promoter was examined by conventional sequencing in
primary brain tumor initiating cells (BTIC), two matched recurrent BTIC lines, a
panel of established malignant glioma cell lines, and two meningioma cell lines.
Telomerase gene expression was examined by quantitative PCR. We found
that...περισσότερα »
Low serum vitamin D is associated with axial length and risk of myopia in young children
Abstract The aim of the study was to investigate
the relationship between serum 25(OH)D levels and axial length (AL) and myopia
in 6-year-old children. A total of 2666 children aged 6 years participating in
the birth-cohort study Generation R underwent a stepwise eye examination. First,
presenting visual acuity (VA) and AL were performed. Second, automated
cycloplegic refraction was measured if LogMAR VA > 0.1. Serum
25-hydroxyvitamin D [25(OH)D] was determined from blood using liquid
chromatography/tandem mass spectrometry. Vitamin D related SNPs were determined
with a SNP array; ...περισσότερα »
New insights on physical activity and amyotrophic lateral sclerosis
from Cancer via ola Kala on Inoreader
http://ift.tt/1peQOsUvia IFTTT
Trajectories of body mass index before the diagnosis of cardiovascular disease: a latent class trajectory analysis
Abstract Patients with cardiovascular disease (CVD)
are a heterogeneous group regarding their body mass index (BMI) levels at the
time of diagnosis. To address the heterogeneity of CVD, we examined the
trajectories of change in body mass index (BMI) and in other cardio-metabolic
risk factors before CVD diagnosis. The study included 6126 participants from the
prospective population-based Rotterdam Study, followed over 22 years with
clinical examinations every 4 years. Latent class trajectory analysis and
mixed-effect models were used to develop trajectories of BMI and other
cardio-...περισσότερα »
A call for specific geriatric data on cervical cancers
Future Oncology Ahead of Print.from Cancer via ola
Kala on Inoreader http://ift.tt/1URWu7Mvia IFTTT
Adjusting to a Diagnosis of Cancer: Processes for Building Patient Capacity for Decision-Making
Abstract This short report contributes to the
expanding body of qualitative research literature about the cognitive processes
of newly diagnosed cancer patients as they adjust to a diagnosis of cancer. The
study is based on secondary qualitative analysis of audio records collected as
part of a larger NIH study (RO1D: An Interdisciplinary Perspective: A Social
Science Examination of Oncofertility RL1 HD058296). Core categories illustrate
the processes of "naming it," "dealing with dealing with it," and finding the
"new norm" and were based on nine patient experiences. We observe
tha...περισσότερα »
IJERPH, Vol. 13, Pages 306: Global Evidence on the Association between POS Advertising Bans and Youth Smoking Participation
Background: Point-of-sale (POS) tobacco advertising
has been linked to youth smoking susceptibility and experimental smoking.
However, there is limited evidence of the association between POS advertising
bans and youth smoking participation. This study aims to examine how such bans
are associated with current smoking, daily smoking, and regular smoking (≥1
cigarettes per day) participation among youth. Methods: one to two waves
(primarily one wave) of the Global Youth Tobacco Survey were conducted in 130
countries between 2007 and 2011. These surveys were linked to the WHO
"MPOWER...περισσότερα »
Energies, Vol. 9, Pages 180: A High-Gain Three-Port Power Converter with Fuel Cell, Battery Sources and Stacked Output for Hybrid Electric Vehicles and DC-Microgrids
This paper proposes a novel high-gain three-port
power converter with fuel cell (FC), battery sources and stacked output for a
hybrid electric vehicle (HEV) connected to a dc-microgrid. In the proposed power
converter, the load power can be flexibly distributed between the input sources.
Moreover, the charging or discharging of the battery storage device can be
controlled effectively using the FC source. The proposed converter has several
outputs in series to achieve a high-voltage output, which makes it suitable for
interfacing with the HEV and dc-microgrid. On the basis of the ch...περισσότερα »
Molecules, Vol. 21, Pages 324: New Cerebroside and Nucleoside Derivatives from a Red Sea Strain of the Marine Cyanobacterium Moorea producens
In the course of our ongoing efforts to identify
marine-derived bioactive compounds, the marine cyanobacterium Moorea producens
was investigated. The organic extract of the Red Sea cyanobacterium afforded one
new cerebroside, mooreaside A (1), two new nucleoside derivatives,
3-acetyl-2′-deoxyuridine (2) and 3-phenylethyl-2′-deoxyuridine (3), along with
the previously reported compounds thymidine (4) and 2,3-dihydroxypropyl
heptacosanoate (5). The structures of the compounds were determined by different
spectroscopic studies (UV, IR, 1D, 2D NMR, and HRESIMS), as well as comparison
...περισσότερα »
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