Tongguan Liqiao acupuncture therapy improves dysphagia after brainstem stroke.
Related Articles *Tongguan Liqiao acupuncture therapy improves dysphagia after brainstem stroke.* Neural Regen Res. 2016 Feb;11(2):285-91 Authors: Zhang CH, Bian JL, Meng ZH, Meng LN, Ren XS, Wang ZL, Guo XY, Shi XM Abstract Tongguan Liqiao acupuncture therapy has been shown to effectively treat dysphagia after stroke-based pseudobulbar paralysis. We presumed that this therapy would be effective for dysphagia after bulbar paralysis in patients with brainstem infarction. Sixty-four patients with dysphagia following brainstem infarction were recruited and divided into a medulla ob...περισσότερα »
MicroRNA-193b inhibits the proliferation, migration and invasion of gastric cancer cells via targeting cyclin D1.
Related Articles *MicroRNA-193b inhibits the proliferation, migration and invasion of gastric cancer cells via targeting cyclin D1.* Acta Histochem. 2016 Apr 9; Authors: Wang L, Zhang Y, Zhao L, Liu S, Yu S, Ma Y, Sun G Abstract MicroRNAs have been involved in RNA silencing and post-transcriptional regulation of gene expression and also play important roles in tumorigenesis and tumor progression. MiR-193b was previously reported to act as tumor suppressor in diverse cancers. However, little is known about the expression, function and mechanism of miR-193b in gastric cancer (GC). ... περισσότερα »
Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice.
Related Articles *Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice.* Parasite. 2016;23:18 Authors: Jang Y, Ahn M, Bang H, Kang B Abstract This study investigated the effects of Kudoa septempunctata genotype ST3 spores on ddY suckling mice. Purified Kudoa septempunctata spores were administered into the stomachs of the mice at 5 × 10(6) or 5 × 10(7) spores/mouse, with inactivated Kudoa (5 × 10(6) spores/mouse) or vehicle as controls. No abnormal clinical symptoms were observed and there were no variations in fluid accumulation ratio and cytokin...περισσότερα »
Predictors of Foreign Body Aspiration in Children.
Related Articles *Predictors of Foreign Body Aspiration in Children.* Otolaryngol Head Neck Surg. 2016 Apr 12; Authors: Sink JR, Kitsko DJ, Georg MW, Winger DG, Simons JP Abstract OBJECTIVES: To examine the sensitivity and specificity of history, physical examination, and radiologic studies as predictors of foreign body aspiration in children. STUDY DESIGN: Case series with chart review. SETTING: Tertiary care children's hospital. SUBJECTS AND METHODS: Medical records were reviewed for 102 children who presented to our institution from 2006 to 2013 with suspected foreign body aspi...περισσότερα »
Cephalic Vein Transposition in the Vessel-Depleted Neck.
Related Articles *Cephalic Vein Transposition in the Vessel-Depleted Neck.* Otolaryngol Head Neck Surg. 2016 Apr 12; Authors: Chan D, Rabbani CC, Inman JC, Ducic Y PMID: 27071445 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1S9fjin via IFTTT
The Role of Surgery in Management of Samter's Triad: A Systematic Review.
Related Articles *The Role of Surgery in Management of Samter's Triad: A Systematic Review.* Otolaryngol Head Neck Surg. 2016 Apr 12; Authors: Adelman J, McLean C, Shaigany K, Krouse JH Abstract OBJECTIVE: Aspirin-exacerbated respiratory disease (AERD) represents a severe form of chronic rhinosinusitis (CRS) characterized by nasal polyposis, bronchial asthma, and aspirin intolerance. This syndrome, known as Samter's triad, is more difficult to manage than routine CRS and poses a challenge to the treating clinician. We performed a systematic review of the literature to determine t...περισσότερα »
Tumor Volume Predicts Survival Rate of Advanced Nasopharyngeal Carcinoma Treated with Concurrent Chemoradiotherapy.
Related Articles *Tumor Volume Predicts Survival Rate of Advanced Nasopharyngeal Carcinoma Treated with Concurrent Chemoradiotherapy.* Otolaryngol Head Neck Surg. 2016 Apr 12; Authors: Qin L, Wu F, Lu H, Wei B, Li G, Wang R Abstract OBJECTIVE: To delineate the prognostic value of primary gross tumor volume (GTVp) for patients with locoregionally advanced nasopharyngeal carcinoma (NPC) treated with concurrent chemoradiotherapy. STUDY DESIGN: Analysis of prognostic variables in a prospective cohort. SETTING: Department of Radiotherapy, First Affiliated Hospital of Guangxi Medical Un... περισσότερα »
Current Role of Dacomitinib in Head and Neck Cancer.
Related Articles *Current Role of Dacomitinib in Head and Neck Cancer.* Expert Opin Investig Drugs. 2016 Apr 12; Authors: Elicin O, Ozsahin M Abstract INTRODUCTION: Recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) has a dismal prognosis. With the emergence of monoclonal antibodies and tyrosine kinase inhibitors (TKI) targeting the epidermal growth factor receptor (EGFR), several drugs were developed and tested in HNSCC. To date, the monoclonal antibody cetuximab is the only approved therapy for curative and recurrent/metastatic patients. Other EGFR-targe... περισσότερα »
Programming the Immune Checkpoint to Treat Hematologic Malignancies.
Related Articles *Programming the Immune Checkpoint to Treat Hematologic Malignancies.* Expert Opin Investig Drugs. 2016 Apr 12; Authors: Vick E, Mahadevan D Abstract INTRODUCTION: Hematologic malignancies manipulate immune suppressive pathways involving CTLA-4, PD-1, and others to promote immune tolerance of cancer. New monoclonal antibodies targeting immune suppressive checkpoints or immune agonist checkpoints are showing meaningful responses in the treatment of relapsed and refractory Hodgkin lymphoma, diffuse large B-cell lymphoma, follicular lymphoma and chronic lymphocytic ... περισσότερα »
FOREARM DXA INCREASES THE RATE OF PATIENTS WITH ASYMPTOMATIC PRIMARY HYPERPARATHYROIDISM MEETING SURGICAL CRITERIA.
Related Articles *FOREARM DXA INCREASES THE RATE OF PATIENTS WITH ASYMPTOMATIC PRIMARY HYPERPARATHYROIDISM MEETING SURGICAL CRITERIA.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20161513 Authors: Castellano E, Attanasio R, Gianotti L, Cesario F, Tassone F, Borretta G Abstract INTRODUCTION: A reduction in bone mineral density (BMD) is common in primary hyperparathyroidism (PHPT), above all at cortical sites. Guidelines for the management of asymptomatic PHPT (aPHPT) recommend a BMD evaluation at the lumbar spine, hip, and forearm. Surgery is recommended for patients with a T-score ≤... περισσότερα »
A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.
Related Articles *A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154329 Authors: Ram Hong A, Kim YA, Hyun Bae J, Sook Min H, Hee Kim J, Soo Shin C, Yeon Kim S, Kim SW Abstract CONTEXT: Gamma-aminobutyric acid-B receptor 1 (GABABR1) forms a heterodimeric complex with calcium-sensing receptor (CaSR) in human brain tissue. However, the expression and implication of GABABR1 in human parathyroid adenoma has not yet been examined. OBJECTIVE: To examine a possible link between G... περισσότερα »
Sunitinib-induced thrombotic microangiopathy
Sunitinib-induced thrombotic microangiopathy: *Vanita Noronha, Sachin Punatar, Amit Joshi, Rushi V Desphande, Kumar Prabhash* Journal of Cancer Research and Therapeutics 2016 12(1):6-11 Sunitinib-induced thrombotic microangiopathy (TMA) is a secondary TMA caused by sunitinib. Despite the extensive use of sunitinib in patients with renal cell carcinoma and other malignancies, little is known about this complication of sunitinib. No clinical trials of sunitinib have studied this complication in any group of patients. We here review the normal physiology of vascular endothelial gro... περισσότερα »
Soft tissue myxofibrosarcoma
A clinico-pathological analysis of a series of 75 patients with emphasis on the epithelioid variant: Background and Objectives The clinical course of soft tissue myxofibrosarcoma is characterized by a high incidence of recurrences and there is no agreement on how to identify patients at major risk. An epithelioid histological variant has been described, with a possible worse prognosis. We reviewed our series to identify prognostic factors and assess clinical significance of the epithelioid variant. Methods We examined the clinico-pathological features of a series of 75 patients aff... περισσότερα »
Association Between Hepatitis C Virus and Head and Neck Cancers
Association Between Hepatitis C Virus and Head and Neck Cancers: *Background:* Hepatitis C virus (HCV) infection is associated with hepatocellular carcinoma and non-Hodgkin’s lymphoma. In 2009, MD Anderson established the first US clinic for treating HCV-infected cancer patients, where we observed an unexpectedly large number of patients with head and neck cancers (HNCs). We sought to determine whether HCV is associated with HNCs. *Methods:* In this case-control study, medical records of cancer patients tested for HCV antibodies at our center from 2004 through 2014 were identified...περισσότερα »
Chemotherapy-induced peripheral neuropathy (CIPN)
PNS drug exposure does not correlate with neurotoxicity: Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect of many antineoplastic agents, but the mechanisms underlying the toxicities of certain drugs are unclear. At their maximal tolerated doses (MTD), the microtubule-binding drugs paclitaxel and ixabepilone induce more severe neuropathy in mice relative to eribulin mesylate, paralleling their toxicity profiles in clinic. We hypothesized that the severity of their neurotoxic effects might be explained by the levels at which they accumulate in the perip... περισσότερα »
AMG 780 in Patients With Advanced Solid Tumors
AMG 780 in Patients With Advanced Solid Tumors: Purpose: To assess the toxicity, pharmacokinetics, tumor vascular response, tumor response, and pharmacodynamics of AMG 780, a monoclonal antibody designed to inhibit the interaction between angiopoietin-1 and -2 and the Tie2 receptor. Experimental Design: This was a phase 1 dose-escalation study of patients with advanced solid tumors refractory to standard treatment without previous antiangiogenic treatment. AMG 780 was administered by intravenous infusion every 2 weeks (Q2W) in doses from 0.1 to 30 mg/kg. The primary endpoints were ... περισσότερα »
VEGF inhibits CD1d-mediated NKT cell activation
VEGF inhibits CD1d-mediated NKT cell activation: Purpose: Natural killer T (NKT) cells are important mediators of anti-tumor immune responses. We have previously shown that ovarian cancers shed the ganglioside GD3, which inhibits NKT cell activation. Ovarian cancers also secrete high levels of vascular endothelial growth factor (VEGF). In this study, we sought to test the hypothesis that VEGF production by ovarian cancers suppresses NKT cell-mediated anti-tumor responses. Experimental Design: To investigate the effects of VEGF on CD1d-mediated NKT cell activation, a conditioned med... περισσότερα »
The human anti-activin receptor-like kinase 1 antibody PF-03446962 in Asian patients with advanced solid tumors
A phase I study of Preclinical studies suggest that ALK-1 signaling mediates a complementary angiogenesis pathway activated upon development of resistance to vascular endothelial growth factor (VEGF)-targeted therapies. Inhibition of ALK-1 signaling may lead to disruption of tumor angiogenesis and growth. We report findings from a multicenter, open-label, phase I study of the fully human anti-ALK-1 mAb PF-03446962 conducted in Japan and South Korea, in Asian patients with advanced solid tumors. The dose escalation Part 1 of the study was based on a standard 3 + 3 design (*n* = 16... περισσότερα »
Concurrent granulomatous polyangiitis and squamous cell carcinoma of the lung
: a case of balancing treatment: Description Granulomatous polyangiitis (GPA) is a rare small-vessel vasculitis characterised by lesions in the upper respiratory tract, lungs and kidneys. Diagnosis of lung lesions can be difficult and misdiagnosis as lung cancer is not uncommon.1 Aggressive, long-term immunosuppression with drugs such as cyclophosphamide is necessary to prevent lung disease and development of end-stage renal failure. We describe a case of a 79-year-old woman with a history of previous breast malignancy who presented with a 6-month history of weight loss and cough. ... περισσότερα »
Topiramate-induced severe heatstroke
in an adult patient: a case report: Heatstroke is a life-threatening condition defined by failure of heat load dissipation, resulting in a core temperature higher than 40 °C (104 °F) associated with neurological dysfunction. Topiramate may cause...
Cancer Vaccines: Past, Present, and Future
Cancer Vaccines: Past, Present, and Future: [image: image]Cancer is a common and potentially deadly disease. Some of the cancers may be difficult to treat by conventional means such as surgery, radiation, and chemotherapy, but may be controlled by the stimulation of the immune response of the body with the help of cancer vaccines. The use of vaccines for preventing infections by oncogenic viruses such as hepatitis B virus and human papilloma virus has been extremely successful in reducing the incidence of cancers resulting from these infections. The use of vaccines for treating canc...περισσότερα »
AMP genomic sequencing procedure microcosting & health economic cost-impact analyses
The Association for Molecular Pathology (AMP), the premier global, non-profit organization serving molecular diagnostic professionals, has announced the results from a 2015 analysis of the costs... from #Audiology via xlomafota13 on Inoreader http://ift.tt/22wpnab via IFTTT
A novel mutation of the MITF gene in a family with Waardenburg syndrome type 2: A case report.
Related Articles *A novel mutation of the MITF gene in a family with Waardenburg syndrome type 2: A case report.* Exp Ther Med. 2016 Apr;11(4):1516-1518 Authors: Shi Y, Li X, Ju D, Li Y, Zhang X, Zhang Y Abstract Waardenburg syndrome (WS) is an autosomal dominant disorder with varying degrees of sensorineural hearing loss, and accumulation of pigmentation in hair, skin and iris. There are four types of WS (WS1-4) with differing characteristics. Mutations in six genes [paired box gene 3 (PAX3), microphthalmia-associated transcription factor (MITF), endothelin 3 (END3), endothelin...περισσότερα »
Ebi, a Drosophila homologue of TBL1, regulates the balance between cellular defense responses and neuronal survival.
Related Articles *Ebi, a Drosophila homologue of TBL1, regulates the balance between cellular defense responses and neuronal survival.* Am J Neurodegener Dis. 2016;5(1):62-8 Authors: Lim YM, Tsuda L Abstract Transducin β-like 1 (TBL1), a transcriptional co-repressor complex, is a causative factor for late-onset hearing impairments. Transcriptional co-repressor complexes play pivotal roles in gene expression by making a complex with divergent transcription factors. However, it remained to be clarified how co-repressor complex regulates cellular survival. We herein demonstrated th... περισσότερα »
New insights in the interpretation of array-CGH: autism spectrum disorder and positive family history for intellectual disability predict the detection of pathogenic variants.
Related Articles *New insights in the interpretation of array-CGH: autism spectrum disorder and positive family history for intellectual disability predict the detection of pathogenic variants.* Ital J Pediatr. 2016;42(1):39 Authors: Cappuccio G, Vitiello F, Casertano A, Fontana P, Genesio R, Bruzzese D, Ginocchio VM, Mormile A, Nitsch L, Andria G, Melis D Abstract BACKGROUND: Array-CGH (aCGH) is presently used into routine clinical practice for diagnosis of patients with intellectual disability (ID), multiple congenital anomalies (MCA), and autism spectrum disorder (ASD). ACGH ...περισσότερα »
Etiology and associated GJB2 mutations in Mauritanian children with non-syndromic hearing loss.
Related Articles *Etiology and associated GJB2 mutations in Mauritanian children with non-syndromic hearing loss.* Eur Arch Otorhinolaryngol. 2016 Apr 11; Authors: Moctar EC, Riahi Z, El Hachmi H, Veten F, Meiloud G, Bonnet C, Abdelhak S, Errami M, Houmeida A Abstract Origins of all hearing impairment forms may be divided into genetic mutations and acquired influence. Both carry damage to the inner ear structure resulting in a mild to profound dysfunction of the auditory system. The purpose of this study was to assess the different etiologies of deafness in two reference centers...περισσότερα »
Mutations in PRPS1 causing syndromic or nonsyndromic hearing impairment: intrafamilial phenotypic variation complicates genetic counseling.
[image: http:--http://ift.tt/1PAyOTB] Related Articles *Mutations in PRPS1 causing syndromic or nonsyndromic hearing impairment: intrafamilial phenotypic variation complicates genetic counseling.* Pediatr Res. 2015 Jul;78(1):97-102 Authors: Gandía M, Fernández-Toral J, Solanellas J, Domínguez-Ruiz M, Gómez-Rosas E, Del Castillo FJ, Villamar M, Moreno-Pelayo MA, Del Castillo I Abstract BACKGROUND: PRPS1 encodes isoform I of phosphoribosylpyrophosphate synthetase (PRS-I), a key enzyme in nucleotide biosynthesis. Different missense mutations in PRPS1 cause a variety of disorders that... περισσότερα »
Cytological features of “non-invasive follicular thyroid neoplasm with papillary-like nuclear features” and their correlation with tumor histology
Cytological features of “non-invasive follicular thyroid neoplasm with papillary-like nuclear features” and their correlation with tumor histology: Among thyroid papillary carcinomas (PTC), the follicular variant is the most common and includes encapsulated forms (EFVPTC). Non-invasive EFVPTC have very low risk of recurrence or other adverse events and have been recently proposed to be designated as “Non-invasive follicular thyroid neoplasm with papillary-like nuclear features” or “NIFTP”, thus eliminating the term “carcinoma”. This proposal is expected to significantly impact the r... περισσότερα »
Novel t(1;3)(q21,p21) translocation in a basal cell adenocarcinoma of the parotid gland
: potential association with tumorigenesis: We report a rare translocation involving chromosomes 1q23 and 3p21 regions in a Basaloid Salivary Carcinoma. Our case together with a previously reported instance of translocation involving chromosome 1q 21–24 region define a specific chromosomal segment that may house a gene associated with the development of a subset of basaloid salivary tumors.
Strong Correlation Between mRNA Expression Levels of HIF-2α, VEGFR1, VEGFR2 and MMP2 in Laryngeal Carcinoma
Strong Correlation Between mRNA Expression Levels of HIF-2α, VEGFR1, VEGFR2 and MMP2 in Laryngeal Carcinoma: AbstractThe hypoxia that arises due to the rapid proliferation of tumor cells is a fundamental driving force for the canonical pathway of neovascularization. In the current study we report a very strong correlation between mRNA expression levels of HIF-2α (but not HIF-1α), VEGFR-1, VEGFR-2 and MMP2 in ex vivo samples from laryngeal carcinoma. Sixty-three samples from patients with histopathologically verified carcinoma of the larynx were examined in this study. Total RNA was...περισσότερα »
Syringe Pump Performance Maintained with IV Filter Use During Low Flow Rate Delivery for Pediatric Patients.
Syringe Pump Performance Maintained with IV Filter Use During Low Flow Rate Delivery for Pediatric Patients.: BACKGROUND: Complex surgical and critically ill pediatric patients rely on syringe infusion pumps for precise delivery of IV medications. Low flow rates and in-line IV filter use may affect drug delivery. To determine the effects of an in-line filter to remove air and/or contaminants on syringe pump performance at low flow rates, we compared the measured rates with the programmed flow rates with and without in-line IV filters. METHODS: Standardized IV infusion assemblies wit...περισσότερα »
Initial Experience of the American Society of Regional Anesthesia and Pain Medicine Coags Regional Smartphone Application
A Novel Report of Global Distribution and Clinical Usage of an Electronic Decision Support Tool to Enhance Guideline Use.: Background and Objectives: Decision support tools have been demonstrated to improve adherence to medical guidelines; however, smartphone applications (apps) have not been studied in this regard. In a collaboration between Vanderbilt University and the American Society of Regional Anesthesia and Pain Medicine (ASRA), the ASRA Coags Regional app was created to be a decision support tool for the 2010 published guideline on regional anesthesia for patients receiving...περισσότερα »
Systemic Lidocaine Fails to Improve Postoperative Pain
But Reduces Time to Discharge Readiness in Patients Undergoing Laparoscopic Sterilization in Day-Case Surgery: A Double-Blind, Randomized, Placebo-Controlled Trial.: Background and Objectives: Perioperative systemic lidocaine provides postoperative analgesia, decreases opioid consumption, and facilitates rehabilitation in abdominal surgery. We hypothesized that systemic lidocaine has analgesic effects in women undergoing day-case laparoscopic sterilization. Methods: Eighty women were randomized in this prospective, double-blind trial to receive either lidocaine (intravenous bolus o... περισσότερα »
Is There Bias against Simulation in Microsurgery Training?
Is There Bias against Simulation in Microsurgery Training?: J reconstr Microsurg DOI: 10.1055/s-0036-1582263 Background While other surgical specialties have embraced virtual reality simulation for training and recertification, microsurgery has lagged. This study aims to assess the opinions of microsurgeons on the role of simulation in microsurgery assessment and training. Methods We surveyed faculty members of the American Society of Reconstructive Microsurgery to ascertain opinions on their use of simulation in training and opinions about the utility of simulation for skills acq... περισσότερα »
A Simple Method to Monitor Skin Cancer
A Simple Method to Monitor Skin Cancer: [image: Collapse Box]Author Information Plastic Surgery Department, University Hospitals of Leicester, Leicester Royal Infirmary, Infirmary Square, Leicester, England, lsayed@doctors.org.uk Plastic Surgery Department, University Hospitals of Leicester, Leicester Royal Infirmary, Infirmary Square, Leicester, England This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properl... περισσότερα »
Is there a correlation between the Clinical Findings and the Radiological Findings in Chronic Maxillary Sinus Atelectasis?
Is there a correlation between the Clinical Findings and the Radiological Findings in Chronic Maxillary Sinus Atelectasis?: Silent sinus syndrome (SSS) is a clinical syndrome that occurs as a result of chronic maxillary sinus atelectasis (CMA) and is seen with progressive enophthalmos and hypoglobus. The aim of this study was to investigate the correlation between radiological findings and clinical findings in patients with radiologically asymmetrical reduced maxillary sinus volume. SummaryObjective Silent sinus syndrome (SSS) is a clinical syndrome that occurs as a result of chron... περισσότερα »
Is a computer-assisted design and computer-assisted manufacturing method for mandibular reconstruction economically viable?
Is a computer-assisted design and computer-assisted manufacturing method for mandibular reconstruction economically viable?: The design and manufacture of patient-specific mandibular reconstruction plates, particularly in combination with cutting guides, has created many new opportunities for the planning and implementation of mandibular reconstruction. Although this surgical method is being used more widely and the outcomes appear to be improved, the question of the additional cost has to be discussed. To evaluate the cost generated by the management of this technology, we studied ...περισσότερα »
Prenatal diagnosis of cleft lip/palate
the surface rendered oro-palatal (SROP) view of the fetal lips and palate, a tool to improve information-sharing within the orofacial team and with the parents: “What does the sonologist need to tell the orofacial team ?” was the question discussed by Mulliken and Benacerraf in 2001 (Mulliken and Benacerraf, 2001). Since that date, the prenatal diagnosis of orofacial clefts has made dramatic advances. Usually, the presence of a cleft is suspected through a noose-mouth coronal view using 2D ultrasonography. When systematic examination of the fetal face is a full part of the examinati... περισσότερα »
Improving the adoption of thyroid cancer clinical practice guidelines
Improving the adoption of thyroid cancer clinical practice guidelines: Objectives/Hypothesis To present an overview of the barriers to the implementation of clinical practice guidelines (CPGs) in thyroid cancer management and to introduce a computer-based clinical support system. Data Sources PubMed. Review Methods: A review of studies on adherence to CPGs was conducted. Results Awareness and adoption of CPGs is low in thyroid cancer management. Barriers to implementation include unfamiliarity with the CPGs and financial concerns. Effective interventions to improve adherence are poss... περισσότερα »
The diagnosis of human papillomavirus-related oropharyngeal carcinoma
Challenges in establishing [image: cover.gif?v=1&s=634ce17de2958347d854769c] Objectives/Hypothesis To describe initial presentations and idiosyncrasies in establishing the diagnosis for human papillomavirus-related (HPV+) compared to HPV-unrelated (HPV−) oropharyngeal carcinoma (OPC). Study Design A single institution retrospective series derived from an institutional prospectively compiled database supplemented by chart review. Methods We reviewed consecutive OPC patients referred to an academic tertiary cancer center from 2009 to 2011. HPV status was evaluated by p16 staining. ... περισσότερα »
Pull-through sialodochoplasty for Stensen's megaduct
*Pull-through sialodochoplasty for Stensen's megaduct* *by Jessica A. Kandl, Adrian A. Ong, M. Boyd Gillespie via The Laryngoscope* Sialendoscopy‐based diagnosis and classification of parotid duct stenoses *M Koch, H Iro, J Zenk - The Laryngoscope, 2009 - Wiley Online Library* *... In some cases a massive duct dilation was visible, which resulted in the formation of a megaduct.In these cases the duct wall appeared to be thin between the encroachments. ... Table II. Stenosesof Stensen's Duct: Extend and Number in the Different Types of Stenoses. ...* *Γίνεται αναφορά σε 32 Σχετικά άρθ... περισσότερα »
Partial and total tonsillectomy on adenoid regrowth
Impact of [image: cover.gif?v=1&s=634ce17de2958347d854769c] Objectives/Hypothesis To compare the rates of adenoid regrowth in children who underwent total tonsillectomy and adenoidectomy (TA) versus partial intracapsular tonsillectomy and adenoidectomy (ITA). Study Design Retrospective cohort study. Methods A medical database was used to retrieve the records of 5,120 children younger than 12 years of age who had an adenoidectomy in combination with a tonsil surgery between April 2008 and September 2014. Children who had symptomatic obstructive sleep apnea without a history of rec... περισσότερα »
Prevalence and associated factors of chronic suppurative otitis media
Data from the Korea National Health and Nutrition Examination Survey, 2009–2012: [image: cover.gif?v=1&s=634ce17de2958347d854769c] Objectives/Hypothesis Chronic suppurative otitis media (CSOM) is a common infectious condition that can cause hearing loss and persistent otorrhea. The prevalence rates of CSOM in developed countries is typically <1%, whereas developing countries and some racial groups have shown higher prevalence rates exceeding 4%. The aim of this study was to investigate the prevalence of CSOM in South Korea and associated factors using data from the Korea Natio...περισσότερα »
Balloon dilation causing tracheal rupture
Endoscopic management and literature review: [image: cover.gif?v=1&s=634ce17de2958347d854769c] A 72-year-old female with a history of idiopathic subglottic tracheal stenosis suffered tracheal rupture during endoscopic balloon dilation. The defect measured 7.5 cm in length, through which the mediastinum was visualized. An 80 × 20-mm silicone-covered tracheobronchial stent was deployed over the defect. The patient was extubated subsequent to intraoperative computed tomography demonstrating minimal air escape. Postoperatively, the patient saw no further complications and was disch...περισσότερα »
Long-term growth rate of vestibular schwannoma in neurofibromatosis 2
A volumetric consideration: [image: cover.gif?v=1&s=634ce17de2958347d854769c] Objectives/Hypothesis To determine the long-term growth rate of vestibular schwannoma (VS) in neurofibromatosis type 2 (NF2) patients based on volumetric measurements. Study Design Retrospective review. Methods We retrospectively reviewed magnetic resonance imaging (MRI) scans acquired from patients with NF2 from 1999 to 2013. Patients with an annual radiologic follow-up over at least 3 consecutive years were included. Volumetric VS growth was prospectively measured using a three-dimensional imaging wo... περισσότερα »
Focus on audiologic impairment in eosinophilic granulomatosis with polyangiitis
Focus on audiologic impairment in eosinophilic granulomatosis with polyangiitis: [image: cover.gif?v=1&s=634ce17de2958347d854769c] Objectives/Hypothesis To evaluate the clinical features of audiologic impairment and its relationship with the nasal, vestibular, and rheumatologic profile in a cohort of patients with eosinophilic granulomatosis with polyangiitis (EGPA), formerly named Churg-Strauss syndrome. Study Design Prospective cross-sectional study. Methods Thirty-nine patients with EGPA, considered controlled according to the Birmingham Vasculitis Activity Score and the Vascu... περισσότερα »
Three-dimensional virtual navigation versus conventional image guidance
A randomized controlled trial: [image: cover.gif?v=1&s=634ce17de2958347d854769c] Objectives/Hypothesis Providing image guidance in a 3-dimensional (3D) format, visually more in keeping with the operative field, could potentially reduce workload and lead to faster and more accurate navigation. We wished to assess a 3D virtual-view surgical navigation prototype in comparison to a traditional 2D system. Methods Thirty-seven otolaryngology surgeons and trainees completed a randomized crossover navigation exercise on a cadaver model. Each subject identified three sinonasal landmarks... περισσότερα »
Genomic Analysis of a Serotype 5 Streptococcus pneumoniae Outbreak in British Columbia, Canada, 2005–2009
Background. Streptococcus pneumoniae can cause a wide spectrum of disease, including invasive pneumococcal disease (IPD). From 2005 to 2009 an outbreak of IPD occurred in Western Canada, caused by a S. pneumoniae strain with multilocus sequence type (MLST) 289 and serotype 5. We sought to investigate the incidence of IPD due to this S. pneumoniae… Continue reading Genomic Analysis of a Serotype 5 Streptococcus pneumoniae Outbreak in British Columbia, Canada, 2005–2009
Hepatitis C Ups Risk Of Head, Neck Cancers: Study – NDTV
NDTV Hepatitis C Ups Risk Of Head, Neck Cancers: Study NDTV Houston: People infected with the hepatitis C virus (HCV) are two to five times more likely to develop certain head and neck cancers, a new study has warned. The findings could have significant implications for both the screening of those with the … Hepatitis… Continue reading Hepatitis C Ups Risk Of Head, Neck Cancers: Study – NDTV
People with Hepatitis C Are Two to Five Times More Likely to Develop Certain Head and Neck Cancers – Newswise (press release)
People with Hepatitis C Are Two to Five Times More Likely to Develop Certain Head and Neck Cancers Newswise (press release) Compared to the controls, the researchers found that the risk for HCV patients of developing specific head and neck cancers was increased 2.4 times for oral cavity cancers, 2.04 times for oropharynx cancers, and… Continue reading People with Hepatitis C Are Two to Five Times More Likely to Develop Certain Head and Neck Cancers – Newswise (press release)
Validity, reliability and interpretability of the Thai version of the urticaria control test (UCT)
The Long Form and Short Form of the German (original) version of the Urticaria Control Test (UCT) have shown to be valid and reliable instruments for assessing patients with all types of chronic urticaria (CU)… from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1Wt21me via IFTTT
How does radiotherapy impact swallowing function in nasopharynx and oropharynx cancer? Short-term results of a prospective study.
Related Articles How does radiotherapy impact swallowing function in nasopharynx and oropharynx cancer? Short-term results of a prospective study. Acta Otorhinolaryngol Ital. 2016 Mar 31; Authors: Ursino S, Seccia V, Cocuzza P, Ferrazza P, Briganti T, Matteucci F, Fatigante L, Giusti P, Grosso M, Locantore L, Morganti R, Nacci A, Sellari Franceschini S, Paiar F,… Continue reading How does radiotherapy impact swallowing function in nasopharynx and oropharynx cancer? Short-term results of a prospective study.
Pneumo-thorax/mediastinum/(retro)peritoneum/ – a full house of complications following JET ventilation.
Related Articles Pneumo-thorax/mediastinum/(retro)peritoneum/ – a full house of complications following JET ventilation. Acta Otorhinolaryngol Ital. 2015 Dec 29; Authors: Pézier TF, Widmer GM, Huber GF Abstract We present a patient who presented to our clinic with airway obstruction secondary to oropharygeal cancer. He underwent emergent tracheostomy with JET ventilation, the latter resulting in a «full… Continue reading Pneumo-thorax/mediastinum/(retro)peritoneum/ – a full house of complications following JET ventilation.
Solitary fibrous tumour of the supraglottic larynx.
Related Articles Solitary fibrous tumour of the supraglottic larynx. Acta Otorhinolaryngol Ital. 2015 Dec 29; Authors: Grammatica G, Bolzoni Villaret A, Ravanelli M, Nicolai P Abstract Solitary fibrous tumour (SFT) is a rare, benign, mesenchymal neoplasm that usually arises in the pleura, but rarely involves other sites outside the serosal space (mediastinum, lung, liver, thyroid… Continue reading Solitary fibrous tumour of the supraglottic larynx.
Effects of simultaneous palatal expansion and mandibular advancement in a child suffering from OSA.
Related Articles Effects of simultaneous palatal expansion and mandibular advancement in a child suffering from OSA. Acta Otorhinolaryngol Ital. 2015 Dec 29; Authors: Galeotti A, Festa P, Pavone M, De Vincentiis GC Abstract This clinical report describes a child suffering from obstructive sleep apnoea (OSA) and class II skeletal malocclusion with maxillary contraction and anterior… Continue reading Effects of simultaneous palatal expansion and mandibular advancement in a child suffering from OSA.
Case 11-2016: A 12-Year-Old Boy with Malaise, Fevers, Abdominal Pain, and Pallor
Presentation of Case. Dr. Katherine L. Tuttle (Pediatrics): A 12-year-old boy was admitted to this hospital because of malaise, fevers, abdominal pain, and worsening pallor. The patient had been well until 1 month before admission, when headache and abdominal pain developed. Examination by a school… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1qqZuMG via IFTTT
Cochlear implantation in delayed sudden hearing loss after conservative vestibular schwannoma surgery.
Related Articles Cochlear implantation in delayed sudden hearing loss after conservative vestibular schwannoma surgery. Acta Otorhinolaryngol Ital. 2015 Dec 29; Authors: Dagna F, Murri A, Albera R, Cuda D Abstract This is a case of successful cochlear implantation in a 50-year-old man who experienced sudden hearing loss and developed ipsilateral severe tinnitus at three years… Continue reading Cochlear implantation in delayed sudden hearing loss after conservative vestibular schwannoma surgery.
Acetyl-DL-leucine improves gait variability in patients with cerebellar ataxia-a case series.
Related Articles *Acetyl-DL-leucine improves gait variability in patients with cerebellar ataxia-a case series.* Cerebellum Ataxias. 2016;3:8 Authors: Schniepp R, Strupp M, Wuehr M, Jahn K, Dieterich M, Brandt T, Feil K Abstract Acetyl-DL-leucine is a modified amino acid that was observed to improve ataxic symptoms in patients with sporadic and hereditary forms of ataxia. Here, we investigated the effect of the treatment with Acetyl-DL-leucine on the walking stability of patients with cerebellar ataxia (10x SAOA, 2x MSA-C, 2x ADA, 1x CACNA-1A mutation, 2x SCA 2, 1x SCA 1). Treatm...περισσότερα »
The effect of intratympanic gentamicin for treatment of Ménière's disease on lower frequency hearing.
Related Articles *The effect of intratympanic gentamicin for treatment of Ménière's disease on lower frequency hearing.* Int J Clin Pharm. 2016 Apr 12; Authors: Sam G, Chung DW, van der Hoeven R, Verweij S, Becker M Abstract Background The intratympanic application of the ototoxic aminoglycoside gentamicin has shown promising results as an ablative treatment for vertigo associated with Ménière's disease. Objective To evaluate the efficacy and safety of intratympanic gentamicin and to specifically analyse the effect of this treatment on high and low hearing frequencies in patients ... περισσότερα »
[Rehabilitation of facial palsy and vertigo in patients with vestibular schwannoma].
Related Articles *[Rehabilitation of facial palsy and vertigo in patients with vestibular schwannoma].* HNO. 2016 Apr 12; Authors: Müller B, Volk GF, Guntinas-Lichius O Abstract BACKGROUND: Facial palsy and vertigo, as symptoms of vestibular schwannoma (VS) or consequences of its therapy, have a significant impact on patients' quality of life. OBJECTIVE: This review analyzed current literature on the topic and deduced recommendations for rehabilitation of facial palsy and vertigo. METHODS: The present review describes a PubMed-based search of the literature of the past 10 years. R... περισσότερα »
Refractory episodic vertigo: role of intratympanic gentamicin and vestibular evoked myogenic potentials.
Related Articles *Refractory episodic vertigo: role of intratympanic gentamicin and vestibular evoked myogenic potentials.* Braz J Otorhinolaryngol. 2016 Mar 28; Authors: Celis-Aguilar E, Hinojosa-González R, Vales-Hidalgo O, Coutinho-Toledo H Abstract INTRODUCTION: Even today, the treatment of intractable vertigo remains a challenge. Vestibular ablation with intratympanic gentamicin stands as a good alternative in the management of refractory vertigo patients. OBJECTIVE: To control intractable vertigo through complete saccular and horizontal canal vestibular ablation with intraty... περισσότερα »
Developing and piloting a multifactorial intervention to address participation and quality of life in nursing home residents with joint contractures (JointConImprove): study protocol.
[image: http:--http://ift.tt/262JK3i] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Developing and piloting a multifactorial intervention to address participation and quality of life in nursing home residents with joint contractures (JointConImprove): study protocol.* Ger Med Sci. 2015;13:Doc13 Authors: Müller M, Bartoszek G, Beutner K, Klingshirn H, Saal S, Stephan AJ, Strobl R, Grill E, Meyer G Abstract BACKGROUND: Joint contractures are common problems in frail older people in nursing homes. Irrespective of the exact extent of older individuals in geriatric care sett... περισσότερα »
Cochlear implant outcomes in patients with superior canal dehiscence.
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Cochlear implant outcomes in patients with superior canal dehiscence.* Cochlear Implants Int. 2015 Jul;16(4):213-21 Authors: Puram SV, Roberts DS, Niesten ME, Dilger AE, Lee DJ Abstract OBJECTIVE: To determine whether adult cochlear implant (CI) users with superior canal dehiscence syndrome (SCDS) or asymptomatic superior semicircular canal dehiscence (SCD) have different surgical, vestibular, and audiologic outcomes when compared to CI users with normal temporal bone anatomy. METHODS: A retrospective single institution review... περισσότερα »
Use of autologous platelet-rich plasma in complete cleft palate repair
Use of autologous platelet-rich plasma in complete cleft palate repair: [image: cover.gif?v=1&s=634ce17de2958347d854769c] Objectives/Hypothesis Evaluate the effect of topical application of autologous platelet-rich plasma (PRP) in primary repair of complete cleft palate and then compare the result with another group of patients using the same surgical technique, without application of PRP with regard to the incidence of oronasal fistula, velopharyngeal closure, and grade of nasality. Study Design Case control study. Methods This study was carried on 44 children with complete cleft... περισσότερα »
Adipose stromal cells improve healing of vocal fold scar
Morphological and functional evidences: [image: cover.gif?v=1&s=634ce17de2958347d854769c] Objectives/Hypothesis Adipose derived stromal cells (ASCs) are abundant and easy to prepare. Such cells may be useful for treating severe vocal disturbance caused by acute vocal fold scars. Study Design Prospective animal experiments with controls. Methods Twenty New-Zealand white rabbits were used in the present study. We evaluated vocal fold healing, with or without injection of autologous ASCs, after acute scarring. A defined lesion was created and the ASCs were immediately injected. Voca... περισσότερα »
Outcome of regenerative therapy for age-related vocal fold atrophy with basic fibroblast growth factor
Outcome of regenerative therapy for age-related vocal fold atrophy with basic fibroblast growth factor: [image: cover.gif?v=1&s=634ce17de2958347d854769c] Objectives/Hypothesis Age-related vocal fold atrophy has become a significant voice disorder as the elderly population grows. However, several therapeutic challenges have limited attempts to improve voice quality. We reported that basic fibroblast growth factor (bFGF) stimulates fibroblasts to produce extracellular matrices such as hyaluronic acid in the lamina propria, leading to a regeneration of pliable vocal folds in animal... περισσότερα »
Differentiating staphylococcal scalded skin syndrome and toxic epidermal necrolysis by optical coherence tomography.
[image: http:--media.wiley.com-assets-7315-19-Wi] *A case report of differentiating staphylococcal scalded skin syndrome and toxic epidermal necrolysis by optical coherence tomography.* Skin Res Technol. Authors: Hussain AA, Banzhaf CA, Themstrup L, Nielsen PL, Jemec GB Abstract BACKGROUND: Staphylococcal scalded skin syndrome (SSSS) and toxic epidermal necrolysis (TEN) both present with acute onset, high morbidity and significant mortality. Rapid diagnosis is therefore of importance. The aim of this study was to investigate and compare the presentation of these diseases using ... περισσότερα »
Cerebral venous thrombosis revealing Behçet disease in a child
*Pan Afr Med J. Publication en ligne 2015 mars 17. French. DOI : 10.11604/pamj.2015.20.259.6321PMCID: PMC4483354* Thrombose veineuse cérébrale révélant une maladie de Behcet chez un enfantCerebral venous thrombosis revealing Behçet disease in a child *Sahar Messaoudi,1,& Maria Rkain,1 Anass Es Seddiki,1 Khalid Serraj,2 Rim Amrani,1 et Noufissa Benajiba1* 1Service de Pédiatrie, CHU Mohamed VI, Oujda, Maroc 2Service de Médecine Interne, CHU Mohamed VI, Oujda, Maroc *&Corresponding author: Sahar Messaoudi, Service de Pédiatrie, CHU Mohamed VI, Oujda, Maroc* *Author information ▼ Article ... περισσότερα »
Management of Stomatitis Associated with Treatment with Everolimus
[Management of Stomatitis Associated with Treatment with Everolimus]. Gan To Kagaku Ryoho. 2016 ; Authors: Ota Y, Kurita H, Umeda M Abstract Stomatitis is a characteristic adverse event of everolimus and other mTOR inhibitors, and occurs at a high incidence and impairs QOL owing to pain. Most cases of stomatitis are mild to moderate. However, when stomatitis becomes serious, it can interfere with the continuation of medication. Therefore, it is important to place more emphasis on the prevention as well as early detection and treatment. In addition, patient education is also import...περισσότερα »
Is colchicine an effective treatment in periodic fever, aphtous stomatitis, pharyngitis, cervical adenitis (PFAPA) syndrome?
Is colchicine an effective treatment in periodic fever, aphtous stomatitis, pharyngitis, cervical adenitis (PFAPA) syndrome? Joint Bone Spine. 2016 Apr 7; Authors: Dusser P, Hentgen V, Neven B, Koné-Paut I Abstract INTRODUCTION: PFAPA syndrome is the most frequent periodic fever syndrome in non-Mediterranean patients. The pathogenesis is unclear and the treatment is purely symptomatic and not standardized. The aim of this study was to assess colchicine's efficacy as prophylactic treatment in PFAPA syndrome and to identify factors able to predict response to treatment. METHODS: We ...περισσότερα »
Cerrobend shielding stents in preventing adverse radiotherapeutic effects in buccal carcinoma patients.
A pilot study to evaluate the efficacy of cerrobend shielding stents in preventing adverse radiotherapeutic effects in buccal carcinoma patients. J Cancer Res Ther. 2016 Authors: Yangchen K, Siddharth R, Singh SV, Singh RD, Aggarwal H, Mishra N, Tripathi S, Srivastava K, Verma T, Kumar P Abstract BACKGROUND: Radiation stents made of Lipowitz metal or cerrobend alloy are commonly used to shield uninvolved tissues from electron beams used in therapeutic radiation treatment of head and neck cancers. However, studies investigating the efficacy of cerrobend shielding stent in patients w...περισσότερα »
Solitary fibrous tumour of the supraglottic larynx.
Solitary fibrous tumour of the supraglottic larynx Acta Otorhinolaryngol Ital. Authors: Grammatica G, Bolzoni Villaret A, Ravanelli M, Nicolai P Abstract Solitary fibrous tumour (SFT) is a rare, benign, mesenchymal neoplasm that usually arises in the pleura, but rarely involves other sites outside the serosal space (mediastinum, lung, liver, thyroid gland); larynx involvement is very rare with only sporadic cases reported in the literature. We report a case of SFT in a 41-year-old woman with supraglottic laryngeal invovlement; symptoms included dysphonia and mild odynophagia lastin... περισσότερα »
Complications following JET ventilation: Pneumo-thorax/mediastinum/(retro)peritoneum/
Pneumo-thorax/mediastinum/(retro)peritoneum/ - a full house of complications following JET ventilation Acta Otorhinolaryngol Ital. Authors: Pézier TF, Widmer GM, Huber GF Abstract We present a patient who presented to our clinic with airway obstruction secondary to oropharygeal cancer. He underwent emergent tracheostomy with JET ventilation, the latter resulting in a "full house" of barotraumatic complications including pneumothorax, pneumomediastinum, pneumoperitoneum, pneumoretroperitoneum and pneumo-scrotum. Free air, while sometimes dramatic as in our case, need not always be ... περισσότερα »
How does radiotherapy impact swallowing function in nasopharynx and oropharynx cancer?
Short-term results of a prospective study.: Authors: Ursino S, Seccia V, Cocuzza P, Ferrazza P, Briganti T, Matteucci F, Fatigante L, Giusti P, Grosso M, Locantore L, Morganti R, Nacci A, Sellari Franceschini S, Paiar F, Caramella D, Fattori B Abstract The objective of this study is to report the initial results of a prospective trial assessing instrumental deglutition function in nasopharynx and oropharynx cancers after radio or chemoradiotherapy using intensity-modulated radiotherapy (IMRT). IMRT was delivered aiming to spare the swallowing organ at risk (SWOARs) for Stage II-IV... περισσότερα »
Craniosynostosis and Resynostosis
Models, Imaging, and Dental Implications: Craniosynostosis occurs in approximately 1 in 2,000 children and results from the premature fusion of ≥1 cranial sutures. If left untreated, craniosynostosis can cause numerous complications as related to an increase in intracranial pressure or as a direct result from cranial deformities, or both. More than 100 known mutations may cause syndromic craniosynostosis, but the majority of cases are nonsyndromic, occurring as isolated defects. Most cases of craniosynostosis require complex cranial vault reconstruction that is associated with a h... περισσότερα »
speech and language; +21 new citations
21 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *speech and language* These pubmed results were generated on 2016/04/14 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Speech via xlomafota13 on Inoreader http://ift.tt/23xqqMF
Immediate effect of laryngeal manual therapy in dysphonic individuals.
*Immediate effect of laryngeal manual therapy in dysphonic individuals.* Codas. 2016 Feb;28(1):59-65 Authors: Reimann AP, Siqueira LT, Rondon AV, Brasolotto AG, Silverio KC Abstract PURPOSES: To investigate the immediate effect of Laryngeal Manual Therapy (LMT) in musculoskeletal pain, in voice and sensations referred to individuals with behavioral dysphonia and individuals without it. METHODS: 30 individuals ranging from 18 to 45 years old were selected and sorted into two groups: the dysphonic group (DG) - 15 individuals with functional or organofunctional dysphonia, and the cont...περισσότερα »
Condition of Vocal Production-Teacher questionnaire: comparison of responses on Likert scale and visual analog scale.
*Condition of Vocal Production-Teacher questionnaire: comparison of responses on Likert scale and visual analog scale.* Codas. 2016 Feb;28(1):53-58 Authors: Giannini SP, Latorre MD, Ferreira LP Abstract PURPOSE: To compare the responses related to vocal symptoms in two versions of the Vocal Production Condition - Teacher (CPV-T) questionnaire, with responses on a Likert scale and a Visual Analog Scale (VAS), in order to evaluate which is the best measurement method. METHODS: A cross-sectional observational study was conducted with teachers with voice disorders during the period fr... περισσότερα »
Communicative aspects and coping strategies in patients with Parkinson's disease.
*Communicative aspects and coping strategies in patients with Parkinson's disease.* Codas. 2016 Feb;28(1):46-52 Authors: Costa FP, Diaféria G, Behlau M Abstract PURPOSE: To investigate, in patients with Parkinson's disease (PD), the coping strategies; the most reported vocal symptoms; and the relation between coping, voice symptoms, and communicative aspects. METHODS: Seventy-three subjects were included in the sample, 33 of which were participants in the experimental group (EG) with diagnosis of PD and 40 were control subjects, that is, healthy and without vocal complaints. They...περισσότερα »
Dysphonia risk screening protocol.
*Dysphonia risk screening protocol.* Clinics (Sao Paulo). 2016 Mar;71(3):114-127 Authors: Nemr K, Simões-Zenari M, Duarte JM, Lobrigate KE, Bagatini FA Abstract OBJECTIVE: To propose and test the applicability of a dysphonia risk screening protocol with score calculation in individuals with and without dysphonia. METHOD: This descriptive cross-sectional study included 365 individuals (41 children, 142 adult women, 91 adult men and 91 seniors) divided into a dysphonic group and a non-dysphonic group. The protocol consisted of 18 questions and a score was calculated using a 10-cm vi... περισσότερα »
Atypical Bilateral Brain Synchronization in the Early Stage of Human Voice Auditory Processing in Young Children with Autism.
*Atypical Bilateral Brain Synchronization in the Early Stage of Human Voice Auditory Processing in Young Children with Autism.* PLoS One. 2016;11(4):e0153077 Authors: Kurita T, Kikuchi M, Yoshimura Y, Hiraishi H, Hasegawa C, Takahashi T, Hirosawa T, Furutani N, Higashida H, Ikeda T, Mutou K, Asada M, Minabe Y Abstract Autism spectrum disorder (ASD) has been postulated to involve impaired neuronal cooperation in large-scale neural networks, including cortico-cortical interhemispheric circuitry. In the context of ASD, alterations in both peripheral and central auditory processes ha...περισσότερα »
Change of speech fundamental frequency explains the satisfaction with voice in response to testosterone therapy in female-to-male gender dysphoric individuals.
Related Articles *Change of speech fundamental frequency explains the satisfaction with voice in response to testosterone therapy in female-to-male gender dysphoric individuals.* Eur Arch Otorhinolaryngol. 2016 Apr 12; Authors: Deuster D, Di Vincenzo K, Szukaj M, Am Zehnhoff-Dinnesen A, Dobel C Abstract Previous studies demonstrated that there is a significant change in speaking fundamental frequency after testosterone therapy in female-to-male gender dysphoric individuals. It is yet an open question how the satisfaction with voice alteration can be predicted because until now it ... περισσότερα »
Voice analysis before and after vocal rehabilitation in patients following open surgery on vocal cords.
Related Articles *Voice analysis before and after vocal rehabilitation in patients following open surgery on vocal cords.* Vojnosanit Pregl. 2016 Feb;73(2):165-8 Authors: Bunijevac M, Petrović-Lazić M, Jovanović-Simić N, Vuković M Abstract BACKGROUND/AIM: The major role of larynx in speech, respiration and swallowing makes carcinomas of this region and their treatment very influential for patients' life quality. The aim of this study was to assess the importance of voice therapy in patients after open surgery on vocal cords. METHODS: This study included 21 male patients and the co... περισσότερα »
[The auditory analysis in the context of the problem of medico-criminalistic identification of the speaker].
Related Articles *[The auditory analysis in the context of the problem of medico-criminalistic identification of the speaker].* Sud Med Ekspert. 2016;59(2):24-26 Authors: Kaganov AS Abstract This article was designed to discuss the theoretical foundations and methodological basis of the auditory component of the comprehensive medico-criminalistic study aimed at the identification of the speaker from his (her) voice and speech. The article is based on the literature data and the materials of forensic and criminalistic examination carried out by the author. PMID: 27070035 [PubMed ... περισσότερα »
Word Intelligibility in Multi-voice Singing: The Influence of Chorus Size.
Related Articles *Word Intelligibility in Multi-voice Singing: The Influence of Chorus Size.* J Voice. 2016 Apr 7; Authors: Condit-Schultz N, Huron D Abstract OBJECTIVE: This study investigated how the intelligibility of sung words is influenced by the number of singers in a choral music style. METHODS: The study used repeated measures factorial. One hundred forty-nine participants listened to recordings of spoken and sung English words and attempted to identify the words. Each stimuli word was sung or spoken in sync by either one, four, eight, sixteen, or twenty-seven members of a... περισσότερα »
Smartphones Offer New Opportunities in Clinical Voice Research.
Related Articles *Smartphones Offer New Opportunities in Clinical Voice Research.* J Voice. 2016 Apr 7; Authors: Manfredi C, Lebacq J, Cantarella G, Schoentgen J, Orlandi S, Bandini A, DeJonckere PH Abstract Smartphone technology provides new opportunities for recording standardized voice samples of patients and sending the files by e-mail to the voice laboratory. This drastically improves the collection of baseline data, as used in research on efficiency of voice treatments. However, the basic requirement is the suitability of smartphones for recording and digitizing pathologic ... περισσότερα »
Perceptions of Voice Teachers Regarding Students' Vocal Behaviors During Singing and Speaking.
Related Articles *Perceptions of Voice Teachers Regarding Students' Vocal Behaviors During Singing and Speaking.* J Voice. 2016 Apr 8; Authors: Beeman SA Abstract OBJECTIVE: This study examined voice teachers' perceptions of their instruction of healthy singing and speaking voice techniques. METHODS: An online, researcher-generated questionnaire based on the McClosky technique was administered to college/university voice teachers listed as members in the 2012-2013 College Music Society directory. RESULTS: A majority of participants believed there to be a relationship between the h... περισσότερα »
Gardasil Vaccination for Recurrent Laryngeal Papillomatosis in Adult Men: First Report: Changes in HPV Antibody Titer.
Related Articles *Gardasil Vaccination for Recurrent Laryngeal Papillomatosis in Adult Men: First Report: Changes in HPV Antibody Titer.* J Voice. 2016 Apr 8; Authors: Makiyama K, Hirai R, Matsuzaki H Abstract BACKGROUND: Patients with human papillomavirus (HPV) DNA-positive recurrent laryngeal papillomatosis commonly have repeated recurrences following surgery. The reason is suspected to be a mechanism by which latent HPV infection in the surrounding healthy mucosa reinfects the surgical site. It may be that production of HPV antibodies in the laryngeal mucosa with Gardasil inje...περισσότερα »
Examining the Impact of Video Modeling Techniques on the Efficacy of Clinical Voice Assessment.
Related Articles *Examining the Impact of Video Modeling Techniques on the Efficacy of Clinical Voice Assessment.* J Voice. 2016 Apr 8; Authors: Werner C, Bowyer S, Weinrich B, Gottliebson R, Brehm SB Abstract OBJECTIVES: The purpose of the current study was to determine whether or not presenting patients with a video model improves efficacy of the assessment as defined by efficiency and decreased variability in trials during the acoustic component of voice evaluations. METHODS: Twenty pediatric participants with a mean age of 7.6 years (SD = 1.50; range = 6-11 years), 32 college-...περισσότερα »
Comparison of Voice Quality Between Patients Who Underwent Inferior Turbinoplasty or Radiofrequency Cauterization.
Related Articles *Comparison of Voice Quality Between Patients Who Underwent Inferior Turbinoplasty or Radiofrequency Cauterization.* J Voice. 2016 Apr 8; Authors: Göker AE, Aydoğdu İ, Saltürk Z, Berkiten G, Atar Y, Kumral TL, Uyar Y Abstract OBJECTIVES: The aim of this study was to analyze and compare the vocal quality in patients who underwent either submucosal turbinectomy or radiofrequency cauterization. METHODS: In this study, we enrolled 60 patients diagnosed with inferior concha hypertrophy. These patients were divided into two groups by using computer program "Research Ra... περισσότερα »
Laryngeal Electromyography for Prognosis of Vocal Fold Paralysis.
Related Articles *Laryngeal Electromyography for Prognosis of Vocal Fold Paralysis.* J Voice. 2016 Apr 5; Authors: Pardo-Maza A, García-Lopez I, Santiago-Pérez S, Gavilán J Abstract OBJECTIVE: This study aimed to determine the value of laryngeal electromyography in the prognosis of vocal fold paralysis. STUDY DESIGN: This is a retrospective descriptive study. MATERIALS AND METHODS: This study included 80 patients diagnosed with unilateral or bilateral vocal fold paralysis on flexible laryngoscopy between 2002 and 2014 in a tertiary medical center. Laryngeal electromyography using a... περισσότερα »
Practical management of periprosthetic leakage in patients rehabilitated with a Provox® 2 voice prosthesis after total laryngectomy.
Related Articles *Practical management of periprosthetic leakage in patients rehabilitated with a Provox® 2 voice prosthesis after total laryngectomy.* Acta Otorrinolaringol Esp. 2016 Apr 8; Authors: Friedlander E, Pinacho Martínez P, Poletti Serafini D, Martín-Oviedo C, Martínez Guirado T, Scola Yurrita B Abstract INTRODUCTION AND OBJECTIVES: Periprosthetic leakage of liquids is a common complication in patients rehabilitated with voice prostheses. Our objective was to describe and review the results of procedures for treating periprosthetic leakage. MATERIALS AND METHODS: This w...περισσότερα »
The role of the speech-language pathologist in maximizing the results of instrumental assessment of velopharyngeal function.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *The role of the speech-language pathologist in maximizing the results of instrumental assessment of velopharyngeal function.* Plast Surg Nurs. 2014 Apr-Jun;34(2):72-4 Authors: Wagreich P PMID: 24887346 [PubMed - indexed for MEDLINE] from Speech via xlomafota13 on Inoreader http://ift.tt/1VYgVQR
Intratympanic Steroid Therapy as a Salvage Treatment for Acute Low-Tone Sensorineural Hearing Loss without Episodes of Vertigo
The Short- and Long-Term Outcome of *Objectives:* To evaluate the hearing outcomes of intratympanic steroid (ITS) treatment for patients with acute low-tone sensorineural hearing loss (ALHL) after failure of initial therapy and to investigate the recurrence and progression to definite Ménière's disease (MD) during a long-term follow-up. *Methods:* We retrospectively reviewed the medical records of 90 patients with refractory ALHL who were followed up for at least 1 year between January 2000 and April 2014. Patients who responded poorly to initial medical treatment received intratym...περισσότερα »
Sound Source Localization by Normal-Hearing Listeners, Hearing-Impaired Listeners and Cochlear Implant Listeners
Sound Source Localization by Normal-Hearing Listeners, Hearing-Impaired Listeners and Cochlear Implant Listeners: *Objective:* Our primary aim was to determine whether listeners in the following patient groups achieve localization accuracy within the 95th percentile of accuracy shown by younger or older normal-hearing (NH) listeners: (1) hearing impaired with bilateral hearing aids, (2) bimodal cochlear implant (CI), (3) bilateral CI, (4) hearing preservation CI, (5) single-sided deaf CI and (6) combined bilateral CI and bilateral hearing preservation. *Design:* The listeners includ... περισσότερα »
Cochlear implantation in adolescents: Factors influencing compliance.
Abstract Objectives To quantify rates of non- and partial-use of cochlear implants (CIs) in adolescent patients implanted in adolescence and childhood and identify factors influencing compliance. Methods A retrospective case note review undertaken at The Manchester Auditory Implant Centre. Adolescents were defined as young people aged 11–18 years. Individuals implanted in adolescence were defined as Group 1, individuals implanted in childhood under the age of 3 years and currently adolescents were defined as Group 2 and individuals implanted between the age of 3 and11 years and curre...περισσότερα »
Mutations in PRPS1 causing syndromic or nonsyndromic hearing impairment
Mutations in PRPS1 causing syndromic or nonsyndromic hearing impairment: intrafamilial phenotypic variation complicates genetic counseling.: [image: http:--www.nature.com-images-lo_pr.gif] Authors: Gandía M, Fernández-Toral J, Solanellas J, Domínguez-Ruiz M, Gómez-Rosas E, Del Castillo FJ, Villamar M, Moreno-Pelayo MA, Del Castillo I Abstract BACKGROUND: PRPS1 encodes isoform I of phosphoribosylpyrophosphate synthetase (PRS-I), a key enzyme in nucleotide biosynthesis. Different missense mutations in PRPS1 cause a variety of disorders that include PRS-I superactivity, nonsyndromic ... περισσότερα »
GJB2 mutations in children with non-syndromic hearing loss.
Etiology and associated GJB2 mutations in Mauritanian children with non-syndromic hearing loss.: Eur Arch Otorhinolaryngol. 2016 Apr 11; Authors: Moctar EC, Riahi Z, El Hachmi H, Veten F, Meiloud G, Bonnet C, Abdelhak S, Errami M, Houmeida A Abstract Origins of all hearing impairment forms may be divided into genetic mutations and acquired influence. Both carry damage to the inner ear structure resulting in a mild to profound dysfunction of the auditory system. The purpose of this study was to assess the different etiologies of deafness in two reference centers for hearing-impaire...περισσότερα »
Mitteilungen der Deutschen Gesellschaft für Pathologie
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
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The MITF gene in a family with Waardenburg syndrome type 2
A novel mutation of the MITF gene in a family with Waardenburg syndrome type 2: A case report.: Related ArticlesExp Ther Med. 2016 Apr;11(4):1516-1518 Authors: Shi Y, Li X, Ju D, Li Y, Zhang X, Zhang Y Abstract Waardenburg syndrome (WS) is an autosomal dominant disorder with varying degrees of sensorineural hearing loss, and accumulation of pigmentation in hair, skin and iris. There are four types of WS (WS1-4) with differing characteristics. Mutations in six genes [paired box gene 3 (PAX3), microphthalmia-associated transcription factor (MITF), endothelin 3 (END3), endothelin re... περισσότερα »
MicroRNA-193b inhibits the proliferation, migration and invasion of gastric cancer cells via targeting cyclin D1.
Related Articles *MicroRNA-193b inhibits the proliferation, migration and invasion of gastric cancer cells via targeting cyclin D1.* Acta Histochem. 2016 Apr 9; Authors: Wang L, Zhang Y, Zhao L, Liu S, Yu S, Ma Y, Sun G Abstract MicroRNAs have been involved in RNA silencing and post-transcriptional regulation of gene expression and also play important roles in tumorigenesis and tumor progression. MiR-193b was previously reported to act as tumor suppressor in diverse cancers. However, little is known about the expression, function and mechanism of miR-193b in gastric cancer (GC). ... περισσότερα »
Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice.
Related Articles *Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice.* Parasite. 2016;23:18 Authors: Jang Y, Ahn M, Bang H, Kang B Abstract This study investigated the effects of Kudoa septempunctata genotype ST3 spores on ddY suckling mice. Purified Kudoa septempunctata spores were administered into the stomachs of the mice at 5 × 10(6) or 5 × 10(7) spores/mouse, with inactivated Kudoa (5 × 10(6) spores/mouse) or vehicle as controls. No abnormal clinical symptoms were observed and there were no variations in fluid accumulation ratio and cytokin...περισσότερα »
Predictors of Foreign Body Aspiration in Children.
Related Articles *Predictors of Foreign Body Aspiration in Children.* Otolaryngol Head Neck Surg. 2016 Apr 12; Authors: Sink JR, Kitsko DJ, Georg MW, Winger DG, Simons JP Abstract OBJECTIVES: To examine the sensitivity and specificity of history, physical examination, and radiologic studies as predictors of foreign body aspiration in children. STUDY DESIGN: Case series with chart review. SETTING: Tertiary care children's hospital. SUBJECTS AND METHODS: Medical records were reviewed for 102 children who presented to our institution from 2006 to 2013 with suspected foreign body aspi...περισσότερα »
Cephalic Vein Transposition in the Vessel-Depleted Neck.
Related Articles *Cephalic Vein Transposition in the Vessel-Depleted Neck.* Otolaryngol Head Neck Surg. 2016 Apr 12; Authors: Chan D, Rabbani CC, Inman JC, Ducic Y PMID: 27071445 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1S9fjin via IFTTT
The Role of Surgery in Management of Samter's Triad: A Systematic Review.
Related Articles *The Role of Surgery in Management of Samter's Triad: A Systematic Review.* Otolaryngol Head Neck Surg. 2016 Apr 12; Authors: Adelman J, McLean C, Shaigany K, Krouse JH Abstract OBJECTIVE: Aspirin-exacerbated respiratory disease (AERD) represents a severe form of chronic rhinosinusitis (CRS) characterized by nasal polyposis, bronchial asthma, and aspirin intolerance. This syndrome, known as Samter's triad, is more difficult to manage than routine CRS and poses a challenge to the treating clinician. We performed a systematic review of the literature to determine t...περισσότερα »
Tumor Volume Predicts Survival Rate of Advanced Nasopharyngeal Carcinoma Treated with Concurrent Chemoradiotherapy.
Related Articles *Tumor Volume Predicts Survival Rate of Advanced Nasopharyngeal Carcinoma Treated with Concurrent Chemoradiotherapy.* Otolaryngol Head Neck Surg. 2016 Apr 12; Authors: Qin L, Wu F, Lu H, Wei B, Li G, Wang R Abstract OBJECTIVE: To delineate the prognostic value of primary gross tumor volume (GTVp) for patients with locoregionally advanced nasopharyngeal carcinoma (NPC) treated with concurrent chemoradiotherapy. STUDY DESIGN: Analysis of prognostic variables in a prospective cohort. SETTING: Department of Radiotherapy, First Affiliated Hospital of Guangxi Medical Un... περισσότερα »
Current Role of Dacomitinib in Head and Neck Cancer.
Related Articles *Current Role of Dacomitinib in Head and Neck Cancer.* Expert Opin Investig Drugs. 2016 Apr 12; Authors: Elicin O, Ozsahin M Abstract INTRODUCTION: Recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) has a dismal prognosis. With the emergence of monoclonal antibodies and tyrosine kinase inhibitors (TKI) targeting the epidermal growth factor receptor (EGFR), several drugs were developed and tested in HNSCC. To date, the monoclonal antibody cetuximab is the only approved therapy for curative and recurrent/metastatic patients. Other EGFR-targe... περισσότερα »
Programming the Immune Checkpoint to Treat Hematologic Malignancies.
Related Articles *Programming the Immune Checkpoint to Treat Hematologic Malignancies.* Expert Opin Investig Drugs. 2016 Apr 12; Authors: Vick E, Mahadevan D Abstract INTRODUCTION: Hematologic malignancies manipulate immune suppressive pathways involving CTLA-4, PD-1, and others to promote immune tolerance of cancer. New monoclonal antibodies targeting immune suppressive checkpoints or immune agonist checkpoints are showing meaningful responses in the treatment of relapsed and refractory Hodgkin lymphoma, diffuse large B-cell lymphoma, follicular lymphoma and chronic lymphocytic ... περισσότερα »
FOREARM DXA INCREASES THE RATE OF PATIENTS WITH ASYMPTOMATIC PRIMARY HYPERPARATHYROIDISM MEETING SURGICAL CRITERIA.
Related Articles *FOREARM DXA INCREASES THE RATE OF PATIENTS WITH ASYMPTOMATIC PRIMARY HYPERPARATHYROIDISM MEETING SURGICAL CRITERIA.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20161513 Authors: Castellano E, Attanasio R, Gianotti L, Cesario F, Tassone F, Borretta G Abstract INTRODUCTION: A reduction in bone mineral density (BMD) is common in primary hyperparathyroidism (PHPT), above all at cortical sites. Guidelines for the management of asymptomatic PHPT (aPHPT) recommend a BMD evaluation at the lumbar spine, hip, and forearm. Surgery is recommended for patients with a T-score ≤... περισσότερα »
Effects of obesity and diabetes on alpha and beta cell mass in surgically resected human pancreas.
Related Articles *Effects of obesity and diabetes on alpha and beta cell mass in surgically resected human pancreas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20161374 Authors: Inaishi J, Saisho Y, Sato S, Kou K, Murakami R, Watanabe Y, Kitago M, Kitagawa Y, Yamada T, Itoh H Abstract CONTEXT: The ethnic difference in beta cell regenerative capacity in response to obesity may be attributable to different phenotypes of type 2 diabetes among ethnicities. OBJECTIVE: This study aimed to clarify the effects of diabetes and obesity on beta (BCM) and alpha cell mass (ACM) in the Japanese ...περισσότερα »
A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.
Related Articles *A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154329 Authors: Ram Hong A, Kim YA, Hyun Bae J, Sook Min H, Hee Kim J, Soo Shin C, Yeon Kim S, Kim SW Abstract CONTEXT: Gamma-aminobutyric acid-B receptor 1 (GABABR1) forms a heterodimeric complex with calcium-sensing receptor (CaSR) in human brain tissue. However, the expression and implication of GABABR1 in human parathyroid adenoma has not yet been examined. OBJECTIVE: To examine a possible link between G... περισσότερα »
The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.
Related Articles *The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154066 Authors: Pierre A, Estienne A, Racine C, Picard JY, Fanchin R, Lahoz B, Alabart JL, Folch J, Jarrier P, Fabre S, Monniaux D, di Clemente N Abstract CONTEXT: Anti-Müllerian hormone (AMH) is produced by the granulosa cells (GCs) of growing follicles and inhibits follicular development. OBJECTIVE: This study aimed to investigate the regulation of the AMH-specific receptor gene (AMHR2) expression in GCs by... περισσότερα »
FOREARM DXA INCREASES THE RATE OF PATIENTS WITH ASYMPTOMATIC PRIMARY HYPERPARATHYROIDISM MEETING SURGICAL CRITERIA.
Related Articles *FOREARM DXA INCREASES THE RATE OF PATIENTS WITH ASYMPTOMATIC PRIMARY HYPERPARATHYROIDISM MEETING SURGICAL CRITERIA.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20161513 Authors: Castellano E, Attanasio R, Gianotti L, Cesario F, Tassone F, Borretta G Abstract INTRODUCTION: A reduction in bone mineral density (BMD) is common in primary hyperparathyroidism (PHPT), above all at cortical sites. Guidelines for the management of asymptomatic PHPT (aPHPT) recommend a BMD evaluation at the lumbar spine, hip, and forearm. Surgery is recommended for patients with a T-score ≤... περισσότερα »
Effects of obesity and diabetes on alpha and beta cell mass in surgically resected human pancreas.
Related Articles *Effects of obesity and diabetes on alpha and beta cell mass in surgically resected human pancreas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20161374 Authors: Inaishi J, Saisho Y, Sato S, Kou K, Murakami R, Watanabe Y, Kitago M, Kitagawa Y, Yamada T, Itoh H Abstract CONTEXT: The ethnic difference in beta cell regenerative capacity in response to obesity may be attributable to different phenotypes of type 2 diabetes among ethnicities. OBJECTIVE: This study aimed to clarify the effects of diabetes and obesity on beta (BCM) and alpha cell mass (ACM) in the Japanese ...περισσότερα »
A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.
Related Articles *A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154329 Authors: Ram Hong A, Kim YA, Hyun Bae J, Sook Min H, Hee Kim J, Soo Shin C, Yeon Kim S, Kim SW Abstract CONTEXT: Gamma-aminobutyric acid-B receptor 1 (GABABR1) forms a heterodimeric complex with calcium-sensing receptor (CaSR) in human brain tissue. However, the expression and implication of GABABR1 in human parathyroid adenoma has not yet been examined. OBJECTIVE: To examine a possible link between G... περισσότερα »
The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.
Related Articles *The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154066 Authors: Pierre A, Estienne A, Racine C, Picard JY, Fanchin R, Lahoz B, Alabart JL, Folch J, Jarrier P, Fabre S, Monniaux D, di Clemente N Abstract CONTEXT: Anti-Müllerian hormone (AMH) is produced by the granulosa cells (GCs) of growing follicles and inhibits follicular development. OBJECTIVE: This study aimed to investigate the regulation of the AMH-specific receptor gene (AMHR2) expression in GCs by... περισσότερα »
Budesonide + formoterol fumarate dihydrate for the treatment of asthma.
Related Articles *Budesonide + formoterol fumarate dihydrate for the treatment of asthma.* Expert Opin Pharmacother. 2016 Apr 12;:1-8 Authors: Wolthers OD Abstract INTRODUCTION: One of the most widely used fixed combinations in asthma management is dry powder budesonide+formoterol fumarate dihydrate which is commercially available as Symbicort Turbuhaler® (and generic products), Easyhaler Bufomix® and DuoRespSpiromax® inhaler. The aim of this paper was to review the fixed dry powder combination of inhaled budesonide+formoterol fumarate dihydrate for asthma treatment in adolescent... περισσότερα »
New molecules and adjuvants in the treatment of infections by Acinetobacter baumannii.
Related Articles *New molecules and adjuvants in the treatment of infections by Acinetobacter baumannii.* Expert Opin Pharmacother. 2016 Apr 11; Authors: Smani Y, Pachón-Ibáñez ME, Pachón J Abstract INTRODUCTION: The current problems of the treatment of infections by Acinetobacter baumannii are linked with the increase of multidrug- and extensive-drug resistance and the lack of development of new antimicrobial drugs for Gram-negative bacilli. For these reasons, new alternatives for the treatment and control of severe infections by A. baumannii are necessary. Several studies have...περισσότερα »
Acetyl-DL-leucine improves gait variability in patients with cerebellar ataxia-a case series.
Related Articles *Acetyl-DL-leucine improves gait variability in patients with cerebellar ataxia-a case series.* Cerebellum Ataxias. 2016;3:8 Authors: Schniepp R, Strupp M, Wuehr M, Jahn K, Dieterich M, Brandt T, Feil K Abstract Acetyl-DL-leucine is a modified amino acid that was observed to improve ataxic symptoms in patients with sporadic and hereditary forms of ataxia. Here, we investigated the effect of the treatment with Acetyl-DL-leucine on the walking stability of patients with cerebellar ataxia (10x SAOA, 2x MSA-C, 2x ADA, 1x CACNA-1A mutation, 2x SCA 2, 1x SCA 1). Treat...περισσότερα »
The effect of intratympanic gentamicin for treatment of Ménière's disease on lower frequency hearing.
Related Articles *The effect of intratympanic gentamicin for treatment of Ménière's disease on lower frequency hearing.* Int J Clin Pharm. 2016 Apr 12; Authors: Sam G, Chung DW, van der Hoeven R, Verweij S, Becker M Abstract Background The intratympanic application of the ototoxic aminoglycoside gentamicin has shown promising results as an ablative treatment for vertigo associated with Ménière's disease. Objective To evaluate the efficacy and safety of intratympanic gentamicin and to specifically analyse the effect of this treatment on high and low hearing frequencies in patients... περισσότερα »
Effects of obesity and diabetes on alpha and beta cell mass in surgically resected human pancreas.
Related Articles *Effects of obesity and diabetes on alpha and beta cell mass in surgically resected human pancreas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20161374 Authors: Inaishi J, Saisho Y, Sato S, Kou K, Murakami R, Watanabe Y, Kitago M, Kitagawa Y, Yamada T, Itoh H Abstract CONTEXT: The ethnic difference in beta cell regenerative capacity in response to obesity may be attributable to different phenotypes of type 2 diabetes among ethnicities. OBJECTIVE: This study aimed to clarify the effects of diabetes and obesity on beta (BCM) and alpha cell mass (ACM) in the Japanese ...περισσότερα »
A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.
Related Articles *A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154329 Authors: Ram Hong A, Kim YA, Hyun Bae J, Sook Min H, Hee Kim J, Soo Shin C, Yeon Kim S, Kim SW Abstract CONTEXT: Gamma-aminobutyric acid-B receptor 1 (GABABR1) forms a heterodimeric complex with calcium-sensing receptor (CaSR) in human brain tissue. However, the expression and implication of GABABR1 in human parathyroid adenoma has not yet been examined. OBJECTIVE: To examine a possible link between G... περισσότερα »
The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.
Related Articles *The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154066 Authors: Pierre A, Estienne A, Racine C, Picard JY, Fanchin R, Lahoz B, Alabart JL, Folch J, Jarrier P, Fabre S, Monniaux D, di Clemente N Abstract CONTEXT: Anti-Müllerian hormone (AMH) is produced by the granulosa cells (GCs) of growing follicles and inhibits follicular development. OBJECTIVE: This study aimed to investigate the regulation of the AMH-specific receptor gene (AMHR2) expression in GCs by... περισσότερα »
FOREARM DXA INCREASES THE RATE OF PATIENTS WITH ASYMPTOMATIC PRIMARY HYPERPARATHYROIDISM MEETING SURGICAL CRITERIA.
Related Articles *FOREARM DXA INCREASES THE RATE OF PATIENTS WITH ASYMPTOMATIC PRIMARY HYPERPARATHYROIDISM MEETING SURGICAL CRITERIA.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20161513 Authors: Castellano E, Attanasio R, Gianotti L, Cesario F, Tassone F, Borretta G Abstract INTRODUCTION: A reduction in bone mineral density (BMD) is common in primary hyperparathyroidism (PHPT), above all at cortical sites. Guidelines for the management of asymptomatic PHPT (aPHPT) recommend a BMD evaluation at the lumbar spine, hip, and forearm. Surgery is recommended for patients with a T-score ≤... περισσότερα »
Effects of obesity and diabetes on alpha and beta cell mass in surgically resected human pancreas.
Related Articles *Effects of obesity and diabetes on alpha and beta cell mass in surgically resected human pancreas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20161374 Authors: Inaishi J, Saisho Y, Sato S, Kou K, Murakami R, Watanabe Y, Kitago M, Kitagawa Y, Yamada T, Itoh H Abstract CONTEXT: The ethnic difference in beta cell regenerative capacity in response to obesity may be attributable to different phenotypes of type 2 diabetes among ethnicities. OBJECTIVE: This study aimed to clarify the effects of diabetes and obesity on beta (BCM) and alpha cell mass (ACM) in the Japanese ...περισσότερα »
A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.
Related Articles *A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154329 Authors: Ram Hong A, Kim YA, Hyun Bae J, Sook Min H, Hee Kim J, Soo Shin C, Yeon Kim S, Kim SW Abstract CONTEXT: Gamma-aminobutyric acid-B receptor 1 (GABABR1) forms a heterodimeric complex with calcium-sensing receptor (CaSR) in human brain tissue. However, the expression and implication of GABABR1 in human parathyroid adenoma has not yet been examined. OBJECTIVE: To examine a possible link between G... περισσότερα »
The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.
Related Articles *The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154066 Authors: Pierre A, Estienne A, Racine C, Picard JY, Fanchin R, Lahoz B, Alabart JL, Folch J, Jarrier P, Fabre S, Monniaux D, di Clemente N Abstract CONTEXT: Anti-Müllerian hormone (AMH) is produced by the granulosa cells (GCs) of growing follicles and inhibits follicular development. OBJECTIVE: This study aimed to investigate the regulation of the AMH-specific receptor gene (AMHR2) expression in GCs by... περισσότερα »
Budesonide + formoterol fumarate dihydrate for the treatment of asthma.
Related Articles *Budesonide + formoterol fumarate dihydrate for the treatment of asthma.* Expert Opin Pharmacother. 2016 Apr 12;:1-8 Authors: Wolthers OD Abstract INTRODUCTION: One of the most widely used fixed combinations in asthma management is dry powder budesonide+formoterol fumarate dihydrate which is commercially available as Symbicort Turbuhaler® (and generic products), Easyhaler Bufomix® and DuoRespSpiromax® inhaler. The aim of this paper was to review the fixed dry powder combination of inhaled budesonide+formoterol fumarate dihydrate for asthma treatment in adolescent... περισσότερα »
New molecules and adjuvants in the treatment of infections by Acinetobacter baumannii.
Related Articles *New molecules and adjuvants in the treatment of infections by Acinetobacter baumannii.* Expert Opin Pharmacother. 2016 Apr 11; Authors: Smani Y, Pachón-Ibáñez ME, Pachón J Abstract INTRODUCTION: The current problems of the treatment of infections by Acinetobacter baumannii are linked with the increase of multidrug- and extensive-drug resistance and the lack of development of new antimicrobial drugs for Gram-negative bacilli. For these reasons, new alternatives for the treatment and control of severe infections by A. baumannii are necessary. Several studies have...περισσότερα »
Acetyl-DL-leucine improves gait variability in patients with cerebellar ataxia-a case series.
Related Articles *Acetyl-DL-leucine improves gait variability in patients with cerebellar ataxia-a case series.* Cerebellum Ataxias. 2016;3:8 Authors: Schniepp R, Strupp M, Wuehr M, Jahn K, Dieterich M, Brandt T, Feil K Abstract Acetyl-DL-leucine is a modified amino acid that was observed to improve ataxic symptoms in patients with sporadic and hereditary forms of ataxia. Here, we investigated the effect of the treatment with Acetyl-DL-leucine on the walking stability of patients with cerebellar ataxia (10x SAOA, 2x MSA-C, 2x ADA, 1x CACNA-1A mutation, 2x SCA 2, 1x SCA 1). Treat...περισσότερα »
The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.
Related Articles *The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154066 Authors: Pierre A, Estienne A, Racine C, Picard JY, Fanchin R, Lahoz B, Alabart JL, Folch J, Jarrier P, Fabre S, Monniaux D, di Clemente N Abstract CONTEXT: Anti-Müllerian hormone (AMH) is produced by the granulosa cells (GCs) of growing follicles and inhibits follicular development. OBJECTIVE: This study aimed to investigate the regulation of the AMH-specific receptor gene (AMHR2) expression in GCs by... περισσότερα »
FOREARM DXA INCREASES THE RATE OF PATIENTS WITH ASYMPTOMATIC PRIMARY HYPERPARATHYROIDISM MEETING SURGICAL CRITERIA.
Related Articles *FOREARM DXA INCREASES THE RATE OF PATIENTS WITH ASYMPTOMATIC PRIMARY HYPERPARATHYROIDISM MEETING SURGICAL CRITERIA.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20161513 Authors: Castellano E, Attanasio R, Gianotti L, Cesario F, Tassone F, Borretta G Abstract INTRODUCTION: A reduction in bone mineral density (BMD) is common in primary hyperparathyroidism (PHPT), above all at cortical sites. Guidelines for the management of asymptomatic PHPT (aPHPT) recommend a BMD evaluation at the lumbar spine, hip, and forearm. Surgery is recommended for patients with a T-score ≤... περισσότερα »
Effects of obesity and diabetes on alpha and beta cell mass in surgically resected human pancreas.
Related Articles *Effects of obesity and diabetes on alpha and beta cell mass in surgically resected human pancreas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20161374 Authors: Inaishi J, Saisho Y, Sato S, Kou K, Murakami R, Watanabe Y, Kitago M, Kitagawa Y, Yamada T, Itoh H Abstract CONTEXT: The ethnic difference in beta cell regenerative capacity in response to obesity may be attributable to different phenotypes of type 2 diabetes among ethnicities. OBJECTIVE: This study aimed to clarify the effects of diabetes and obesity on beta (BCM) and alpha cell mass (ACM) in the Japanese ...περισσότερα »
A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.
Related Articles *A possible link between parathyroid hormone secretion and local regulation of GABA in human parathyroid adenomas.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154329 Authors: Ram Hong A, Kim YA, Hyun Bae J, Sook Min H, Hee Kim J, Soo Shin C, Yeon Kim S, Kim SW Abstract CONTEXT: Gamma-aminobutyric acid-B receptor 1 (GABABR1) forms a heterodimeric complex with calcium-sensing receptor (CaSR) in human brain tissue. However, the expression and implication of GABABR1 in human parathyroid adenoma has not yet been examined. OBJECTIVE: To examine a possible link between G... περισσότερα »
The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.
Related Articles *The bone morphogenetic protein 15 up-regulates the anti-Müllerian hormone receptor expression in granulosa cells.* J Clin Endocrinol Metab. 2016 Apr 12;:jc20154066 Authors: Pierre A, Estienne A, Racine C, Picard JY, Fanchin R, Lahoz B, Alabart JL, Folch J, Jarrier P, Fabre S, Monniaux D, di Clemente N Abstract CONTEXT: Anti-Müllerian hormone (AMH) is produced by the granulosa cells (GCs) of growing follicles and inhibits follicular development. OBJECTIVE: This study aimed to investigate the regulation of the AMH-specific receptor gene (AMHR2) expression in GCs by... περισσότερα »
Budesonide + formoterol fumarate dihydrate for the treatment of asthma.
Related Articles *Budesonide + formoterol fumarate dihydrate for the treatment of asthma.* Expert Opin Pharmacother. 2016 Apr 12;:1-8 Authors: Wolthers OD Abstract INTRODUCTION: One of the most widely used fixed combinations in asthma management is dry powder budesonide+formoterol fumarate dihydrate which is commercially available as Symbicort Turbuhaler® (and generic products), Easyhaler Bufomix® and DuoRespSpiromax® inhaler. The aim of this paper was to review the fixed dry powder combination of inhaled budesonide+formoterol fumarate dihydrate for asthma treatment in adolescent... περισσότερα »
New molecules and adjuvants in the treatment of infections by Acinetobacter baumannii.
Related Articles *New molecules and adjuvants in the treatment of infections by Acinetobacter baumannii.* Expert Opin Pharmacother. 2016 Apr 11; Authors: Smani Y, Pachón-Ibáñez ME, Pachón J Abstract INTRODUCTION: The current problems of the treatment of infections by Acinetobacter baumannii are linked with the increase of multidrug- and extensive-drug resistance and the lack of development of new antimicrobial drugs for Gram-negative bacilli. For these reasons, new alternatives for the treatment and control of severe infections by A. baumannii are necessary. Several studies have...περισσότερα »
Acetyl-DL-leucine improves gait variability in patients with cerebellar ataxia-a case series.
Related Articles *Acetyl-DL-leucine improves gait variability in patients with cerebellar ataxia-a case series.* Cerebellum Ataxias. 2016;3:8 Authors: Schniepp R, Strupp M, Wuehr M, Jahn K, Dieterich M, Brandt T, Feil K Abstract Acetyl-DL-leucine is a modified amino acid that was observed to improve ataxic symptoms in patients with sporadic and hereditary forms of ataxia. Here, we investigated the effect of the treatment with Acetyl-DL-leucine on the walking stability of patients with cerebellar ataxia (10x SAOA, 2x MSA-C, 2x ADA, 1x CACNA-1A mutation, 2x SCA 2, 1x SCA 1). Treat...περισσότερα »
Sports, Vol. 4, Pages 23: The Effects of Mental Imagery with Video-Modeling on Self-Efficacy and Maximal Front Squat Ability
This study was designed to assess the effectiveness of mental imagery supplemented with video-modeling on self-efficacy and front squat strength (three repetition maximum; 3RM). Subjects (13 male, 7 female) who had at least 6 months of front squat experience were assigned to either an experimental (n = 10) or a control (n = 10) group. Subjects′ 3RM and self-efficacy for the 3RM were measured at baseline. Following this, subjects in the experimental group followed a structured imagery protocol, incorporating video recordings of both their own 3RM performance and a model lifter with... περισσότερα »
Atmosphere, Vol. 7, Pages 57: Effect of Pollution Controls on Atmospheric PM2.5 Composition during Universiade in Shenzhen, China
The 16th Universiade, an international multi-sport event, was hosted in Shenzhen, China from 12 to 23 August 2011. During this time, officials instituted the Pearl River Delta action plan in order to enhance the air quality of Shenzhen. To determine the effect of these controls, the current study examined the trace elements, water-soluble ions, and stable lead isotopic ratios in atmospheric particulate matter (PM) collected during the controlled (when the restrictions were in place) and uncontrolled periods. Fine particles (PM2.5) were collected at two sampling sites in Shenzhen: ... περισσότερα »
Nutrients, Vol. 8, Pages 222: Wine Resveratrol: From the Ground Up
The ability of the grapevine to activate defense mechanisms against some pathogens has been shown to be linked to the synthesis of resveratrol and other stilbenes by the plant (inducible viniferins). Metabolized viniferins may also be produced or modified by extracellular enzymes released by the pathogen in an attempt to eliminate undesirable toxic compounds. Because of the important properties of resveratrol, there is increasing interest in producing wines with higher contents of this compound and a higher nutritional value. Many biotic and abiotic elicitors can trigger the resve... περισσότερα »
Harm reduction interventions in HIV care: a qualitative exploration of patient and provider perspectives
Background. A culture of stringent drug policy, one-size-fits-all treatment approaches, and drug-related stigma has clouded clinical HIV practice in the United States. The result is a series of missed opportunities in the HIV care environment. An approach which may address the broken relationship between patient and provider is harm reduction—which removes judgment and operates at the patient's stage of readiness. Harm reduction is not a routine part of care; rather, it exists outside clinic walls, exacerbating the divide between compassionate, stigma-free services and the medical ... περισσότερα »
Translation and validation of the Child and the Adolescent HARDSHIP (Headache-attributed restriction, disability, social handicap and impaired participation) questionnaire into Danish language
Background. The prevalence of headaches among children and adolescents varies considerably between countries. This may be due to a lack of appropriate instruments to capture the prevalence. The purpose of this study was to translate the Child and Adolescent HARDSHIP questionnaires from English into Danish language, conduct cross-cultural adaptation, face validation by cognitive interviewing and conduct a pilot study exploring time requirements. Methods. The questionnaire was translated using the guidelines proposed by "The Global Campaign to Reduce the Burden of Headache." A total...περισσότερα »
The role of Rnf in ion gradient formation in Desulfovibrio alaskensis
[image: fig-1-1x.jpg] Rnf is a membrane protein complex that has been shown to be important in energy conservation. Here, Desulfovibrio alaskensis G20 and Rnf mutants of G20 were grown with different electron donor and acceptor combinations to determine the importance of Rnf in energy conservation and the type of ion gradient generated. The addition of the protonophore TCS strongly inhibited lactate-sulfate dependent growth whereas the sodium ionophore ETH2120 had no effect, indicating a role for the proton gradient during growth. Mutants in rnfA and rnfD were more sensitive to the... περισσότερα »
The macroevolution of size and complexity in insect male genitalia
[image: fig-1-1x.jpg] The evolution of insect male genitalia has received much attention, but there is still a lack of data on the macroevolutionary origin of its extraordinary variation. We used a calibrated molecular phylogeny of 71 of the 150 known species of the beetle genus Limnebius to study the evolution of the size and complexity of the male genitalia in its two subgenera, Bilimneus, with small species with simple genitalia, and Limnebius s.str., with a much larger variation in size and complexity. We reconstructed ancestral values of complexity (perimeter and fractal dimen... περισσότερα »
Preliminary study on non-viral transfection of F9 (factor IX) gene by nucleofection in human adipose-derived mesenchymal stem cells
[image: fig-1-1x.jpg] Background. Hemophilia is a rare recessive X-linked disease characterized by a deficiency of coagulation factor VIII or factor IX. Its current treatment is merely palliative. Advanced therapies are likely to become the treatment of choice for the disease as they could provide a curative treatment. Methods. The present study looks into the use of a safe non-viral transfection method based on nucleofection to express and secrete human clotting factor IX (hFIX) where human adipose tissue derived mesenchymal stem cells were used as target cells in vitro studies an... περισσότερα »
Natural selection drives chemical resistance of Datura stramonium
[image: fig-1-1x.jpg] Plant resistance to herbivores involves physical and chemical plant traits that prevent or diminish damage by herbivores, and hence may promote coevolutionary arm-races between interacting species. Although Datura stramonium's concentration of tropane alkaloids is under selection by leaf beetles, it is not known whether chemical defense reduces seed predation by the specialist weevil, Trichobaris soror, and if it is evolving by natural selection. We measured infestation by T. soror as well as the concentration of the plants' two main tropane alkaloids in 278 D... περισσότερα »
Laminectomy plus Fusion versus Laminectomy Alone for Lumbar Spondylolisthesis
The increased use of the lumbar spinal fusion procedure in the United States, along with the wide variation in practice, is attracting interest from multiple stakeholders, including patients, physicians, payers, and policymakers. In a report published in 2014, spinal fusion (465,000 hospital-based… from #Medicine via ola Kala on Inoreader http://ift.tt/1Na1ROr via IFTTT
A Randomized, Controlled Trial of Fusion Surgery for Lumbar Spinal Stenosis
Lumbar spinal stenosis is caused by a gradual narrowing of the spinal canal. Patients with lumbar spinal stenosis typically present with low back pain and leg pain, which occur especially when they are walking. This degenerative condition severely restricts function, walking ability, and quality of… from #Medicine via ola Kala on Inoreader http://ift.tt/1Na1ROj via IFTTT
Longitudinal association between gross motor capacity and neuromusculoskeletal function in children and youth with cerebral palsy
Publication date: Available online 13 April 2016 *Source:*Archives of Physical Medicine and Rehabilitation Author(s): Rimke C. Vos, Jules G. Becher, Jeanine M. Voorman, Jan Willem Gorter, Mirjam van Eck, Jetty van Meeteren, Dirk-Wouter Smits, Jos WR. Twisk, Annet J. Dallmeijer ObjectiveTo examine associations over longitudinal measurements between neuromusculoskeletal function and gross motor capacity in children and youth with Cerebral Palsy (CP).DesignA prospective cohort studySettingRehabilitation departments of university medical centers and rehabilitations centers in The Nether... περισσότερα »
Thalamic Functional Connectivity in Mild Traumatic Brain Injury: Longitudinal Associations with Patient-Reported Outcomes and Neuropsychological Tests
Publication date: Available online 13 April 2016 *Source:*Archives of Physical Medicine and Rehabilitation Author(s): Sarah D. Banks, Rogelio A. Coronado, Lori R. Clemons, Christine M. Abraham, Sumit Pruthi, Benjamin N. Conrad, Victoria L. Morgan, Oscar D. Guillamondegui, Kristin R. Archer ObjectiveTo examine: (1) differences in patient-reported outcomes, neuropsychological tests, and thalamic functional connectivity (FC) between patients with mild traumatic brain injury (mTBI) and healthy controls; (2) the longitudinal association between changes in these measures.DesignProspective...περισσότερα »
A Comparison of Rates of Hospitalization and Emergency Department Visits Using Self-report and South Carolina Administrative Billing Data Among a Population-based Cohort with Spinal Cord Injury
Publication date: Available online 12 April 2016 *Source:*Archives of Physical Medicine and Rehabilitation Author(s): Lee L. Saunders, David Murday, Beth Corley, Yue Cao, James S. Krause ObjectiveTo compare self-report and South Carolina (SC) administrative billing data documentation of emergency department (ED) visits and hospitalizations in the past 12 months among a population-based cohort of persons with spinal cord injury (SCI).DesignCross-sectionalSettingSCI Surveillance System in SCParticipantsPersons sustaining a traumatic SCI between 1998 and 2011 in SC who, at the time of ...περισσότερα »
The Immediate Biomechanical Implications of Transfer Component Skills Training on Independent Wheelchair Transfers
Publication date: Available online 12 April 2016 *Source:*Archives of Physical Medicine and Rehabilitation Author(s): Chung-Ying Tsai, Michael L. Boninger, Jennifer Hastings, Rory A. Cooper, Laura Rice, Alicia M. Koontz ObjectiveTo evaluate the immediate effects of transfer training based on the Transfer Assessment Instrument (TAI) on the UL biomechanics during transfers.DesignPre-post interventionSettingBiomechanics laboratoryParticipantsTwenty-four full-time manual wheelchair users (MWUs) performed up to five transfers to a level height bench while their natural transfer skills we... περισσότερα »
Comorbid traumatic brain injury and spinal cord injury: Screening validity and effect on outcomes
Publication date: Available online 12 April 2016 *Source:*Archives of Physical Medicine and Rehabilitation Author(s): Charles H. Bombardier, Darren C. Lee, Debbie L. Tan, Jason Barber, Jeanne M. Hoffman ObjectiveTo determine the diagnostic accuracy of a self-report measure of traumatic brain injury (TBI) in people with spinal cord injury (SCI) and to assess the potential effect of TBI on acute and post-acute outcomes.DesignWe compared incident TBI as determined by self-report versus systematic medical records review by physicians blinded to self-reported TBI.SettingInpatient rehabil...περισσότερα »
Advances on Software Defined Sensor, Mobile, and Fixed Networks
from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1T6e45U via IFTTT
Penetrating injury of the soft palate by a microlaryngeal tracheal tube during GlideScope® intubation.
Related Articles Penetrating injury of the soft palate by a microlaryngeal tracheal tube during GlideScope® intubation. Acta Otorhinolaryngol Ital. 2015 Dec 29; Authors: Alfahel WS, Aouad MT, Siddik-Sayyid SM PMID: 27070535 [PubMed – as supplied by publisher] from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1VYdgTb via IFTTT
Efficiency Analysis of Direct Video-Assisted Thoracoscopic Surgery in Elderly Patients with Blunt Traumatic Hemothorax without an Initial Thoracostomy
Hemothorax is common in elderly patients following blunt chest trauma. Traditionally, tube thoracostomy is the first choice for managing this complication. The goal of this study was to determine the benefits of this approach in elderly patients with and without an initial tube thoracostomy. Seventy-eight patients aged >65 years with blunt chest trauma and stable… Continue reading Efficiency Analysis of Direct Video-Assisted Thoracoscopic Surgery in Elderly Patients with Blunt Traumatic Hemothorax without an Initial Thoracostomy
Adverse Reactions to Gadoterate Meglumine: Review of Over 25 Years of Clinical Use and More Than 50 Million Doses.
Objective: The aim of this study was to evaluate the safety profile of gadoterate meglumine from clinical trials, postmarketing observational studies, and pharmacovigilance reports of adverse drug reactions (ADRs) encompassing 25 years of clinical use and over 50 million administered doses. Materials and Methods: Assessment of the safety of gadoterate meglumine through processing and review… Continue reading Adverse Reactions to Gadoterate Meglumine: Review of Over 25 Years of Clinical Use and More Than 50 Million Doses.
Paralyzed man controls hand and fingers using brain implant
A chip implanted in his brain and linked to a computer allows a man left quadriplegic 6 years ago from a broken neck to grasp and manipulate objects with his own hand and fingers. from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1p0qAJF via IFTTT
Is cocaine a safe topical agent for use during endoscopic sinus surgery?
(Source: The Laryngoscope) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1ShpIy2 via IFTTT
Case 11-2016: A 12-Year-Old Boy with Malaise, Fevers, Abdominal Pain, and Pallor
Presentation of Case. Dr. Katherine L. Tuttle (Pediatrics): A 12-year-old boy was admitted to this hospital because of malaise, fevers, abdominal pain, and worsening pallor. The patient had been well until 1 month before admission, when headache and abdominal pain developed. Examination by a school… from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1qqZuMG via IFTTT
Fitte Diabetiker rutschen schneller in den Unterzucker
Diabetes Typ 1 und Sport Mit der körperlichen Fitness steigt für Typ-1-Diabetiker offenbar das Hypoglykämierisiko beim Sport. from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1SNQTe9 via IFTTT
The effect of anchors on reliability of endoscopic tremor ratings
ConclusionsConsistent, reproducible ratings are critical for the interpretation and comparison of endoscopic tremor data. Reliability findings from this study indicate that the use of anchor samples as referents for making ordinal judgments about the severity of tremor in oropharyngeal and laryngeal regions was helpful for improving internal standards and consistency but less useful for calibrating… Continue reading The effect of anchors on reliability of endoscopic tremor ratings
Impact of partial and total tonsillectomy on adenoid regrowth
ConclusionsITA seems to be a safe procedure with a low incidence of regrowth of adenoid tissue in children with adenotonsillar hypertrophy when compared to TA. Level of Evidence4. Laryngoscope, 2016 (Source: The Laryngoscope) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1Vng1OC via IFTTT
Frequency and factors associated with dysphagia in stroke.
*Frequency and factors associated with dysphagia in stroke.* Codas. 2016 Feb;28(1):66-70 Authors: Mourão AM, Lemos SM, Almeida EO, Vicente LC, Teixeira AL Abstract PURPOSE: To investigate the frequency of dysphagia in acute stroke and the possible associated clinical and sociodemographic features. METHOD: A cross-sectional study was performed including 100 stroke patients who were admitted to the Minas Gerais Regional Public Hospital. Sociodemographic and clinical data were collected, and the patients underwent clinical evaluation through the Gugging Swallowing Screen (GUSS). RESUL... περισσότερα »
Condition of Vocal Production-Teacher questionnaire: comparison of responses on Likert scale and visual analog scale.
*Condition of Vocal Production-Teacher questionnaire: comparison of responses on Likert scale and visual analog scale.* Codas. 2016 Feb;28(1):53-58 Authors: Giannini SP, Latorre MD, Ferreira LP Abstract PURPOSE: To compare the responses related to vocal symptoms in two versions of the Vocal Production Condition - Teacher (CPV-T) questionnaire, with responses on a Likert scale and a Visual Analog Scale (VAS), in order to evaluate which is the best measurement method. METHODS: A cross-sectional observational study was conducted with teachers with voice disorders during the period fr... περισσότερα »
Comparison of Cartesian and Non-Cartesian Real-Time MRI Sequences at 1.5T to Assess Velar Motion and Velopharyngeal Closure during Speech.
*Comparison of Cartesian and Non-Cartesian Real-Time MRI Sequences at 1.5T to Assess Velar Motion and Velopharyngeal Closure during Speech.* PLoS One. 2016;11(4):e0153322 Authors: Freitas AC, Wylezinska M, Birch MJ, Petersen SE, Miquel ME Abstract Dynamic imaging of the vocal tract using real-time MRI has been an active and growing area of research, having demonstrated great potential to become routinely performed in the clinical evaluation of speech and swallowing disorders. Although many technical advances have been made in regards to acquisition and reconstruction methodologies... περισσότερα »
Kommerell Diverticulum Should Be Removed in Children With Vascular Ring and Aberrant Left Subclavian Artery.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Kommerell Diverticulum Should Be Removed in Children With Vascular Ring and Aberrant Left Subclavian Artery.* Ann Thorac Surg. 2015 Dec;100(6):2293-7 Authors: Luciano D, Mitchell J, Fraisse A, Lepidi H, Kreitmann B, Ovaert C Abstract BACKGROUND: Right aortic arch with aberrant left subclavian artery is the most frequent cause of vascular ring. Ligamentum arteriosus division opens the ring but leaves the Kommerell diverticulum in place, with a risk of residual compression, aneurysmal dilation, dissection, or even ru... περισσότερα »
Randomised clinical trial: the clinical efficacy and safety of an alginate-antacid (Gaviscon Double Action) versus placebo, for decreasing upper gastrointestinal symptoms in symptomatic gastroesophageal reflux disease (GERD) in China.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Randomised clinical trial: the clinical efficacy and safety of an alginate-antacid (Gaviscon Double Action) versus placebo, for decreasing upper gastrointestinal symptoms in symptomatic gastroesophageal reflux disease (GERD) in China.* Aliment Pharmacol Ther. 2015 Oct;42(7):845-54 Authors: Sun J, Yang C, Zhao H, Zheng P, Wilkinson J, Ng B, Yuan Y Abstract BACKGROUND: There is a paucity of large-scale studies evaluating the clinical benefit of the Gaviscon Double Action (DA) alginate-antacid formulation for treatin... περισσότερα »
Influence of respiratory physiotherapy on gastro-oesophageal reflux in infants: A systematic review.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Influence of respiratory physiotherapy on gastro-oesophageal reflux in infants: A systematic review.* Pediatr Pulmonol. 2015 Sep;50(9):936-44 Authors: Van Ginderdeuren F, Kerckhofs E, Deneyer M, Vanlaethem S, Vandenplas Y Abstract PURPOSE: To provide a survey on the literature concerning the influence of respiratory physiotherapy on gastro-oesophageal reflux (GOR) in infants and young children. METHODS: Electronic databases (Pubmed, Web of Science, PEDro) and reference lists of articles and narrative reviews were ... περισσότερα »
Symptoms of Obstructive Sleep Apnea, Gastroesophageal Reflux and the Risk of Barrett's Esophagus in a Population-Based Case-Control Study.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Symptoms of Obstructive Sleep Apnea, Gastroesophageal Reflux and the Risk of Barrett's Esophagus in a Population-Based Case-Control Study.* PLoS One. 2015;10(6):e0129836 Authors: Lindam A, Kendall BJ, Thrift AP, Macdonald GA, O'Brien S, Lagergren J, Whiteman DC Abstract BACKGROUND: Gastroesophageal reflux is overrepresented in people with obstructive sleep apnea (OSA) and it has been suggested that OSA worsens gastroesophageal reflux symptoms. Aggravated reflux might lead to an increased...περισσότερα »
Caffeine impairs gastrointestinal function in newborn rats.
[image: http:--http://ift.tt/1PAyOTB] Related Articles *Caffeine impairs gastrointestinal function in newborn rats.* Pediatr Res. 2015 Jul;78(1):24-8 Authors: Welsh C, Pan J, Belik J Abstract BACKGROUND: Feeding intolerance is commonly documented in premature infants. Caffeine is routinely utilized for apnea of prematurity treatment and known to reduce the lower esophageal sphincter (LES) muscle tone, but the caffeine effect on the newborn gastrointestinal function is unknown. We hypothesized that caffeine impairs esophageal and gastrointestinal motor function. As such, we investi... περισσότερα »
Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia.* Pediatr Pulmonol. 2015 Jun;50(6):584-7 Authors: Jensen EA, Munson DA, Zhang H, Blinman TA, Kirpalani H Abstract Gastroesophageal reflux may exacerbate lung disease in infants with bronchopulmonary dysplasia (BPD). Anti-reflux surgery may therefore reduce the severity of this disease in some infants. We report a retrospective series of 22 infants with severe BPD who underwent anti-reflux surgery. Our experience indicates that t... περισσότερα »
Symptoms of Obstructive Sleep Apnea, Gastroesophageal Reflux and the Risk of Barrett's Esophagus in a Population-Based Case-Control Study.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Symptoms of Obstructive Sleep Apnea, Gastroesophageal Reflux and the Risk of Barrett's Esophagus in a Population-Based Case-Control Study.* PLoS One. 2015;10(6):e0129836 Authors: Lindam A, Kendall BJ, Thrift AP, Macdonald GA, O'Brien S, Lagergren J, Whiteman DC Abstract BACKGROUND: Gastroesophageal reflux is overrepresented in people with obstructive sleep apnea (OSA) and it has been suggested that OSA worsens gastroesophageal reflux symptoms. Aggravated reflux might lead to an increase...περισσότερα »
Caffeine impairs gastrointestinal function in newborn rats.
[image: http:--http://ift.tt/1PAyOTB] Related Articles *Caffeine impairs gastrointestinal function in newborn rats.* Pediatr Res. 2015 Jul;78(1):24-8 Authors: Welsh C, Pan J, Belik J Abstract BACKGROUND: Feeding intolerance is commonly documented in premature infants. Caffeine is routinely utilized for apnea of prematurity treatment and known to reduce the lower esophageal sphincter (LES) muscle tone, but the caffeine effect on the newborn gastrointestinal function is unknown. We hypothesized that caffeine impairs esophageal and gastrointestinal motor function. As such, we invest... περισσότερα »
Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia.* Pediatr Pulmonol. 2015 Jun;50(6):584-7 Authors: Jensen EA, Munson DA, Zhang H, Blinman TA, Kirpalani H Abstract Gastroesophageal reflux may exacerbate lung disease in infants with bronchopulmonary dysplasia (BPD). Anti-reflux surgery may therefore reduce the severity of this disease in some infants. We report a retrospective series of 22 infants with severe BPD who underwent anti-reflux surgery. Our experience indicates that ... περισσότερα »
Frequency and factors associated with dysphagia in stroke.
*Frequency and factors associated with dysphagia in stroke.* Codas. 2016 Feb;28(1):66-70 Authors: Mourão AM, Lemos SM, Almeida EO, Vicente LC, Teixeira AL Abstract PURPOSE: To investigate the frequency of dysphagia in acute stroke and the possible associated clinical and sociodemographic features. METHOD: A cross-sectional study was performed including 100 stroke patients who were admitted to the Minas Gerais Regional Public Hospital. Sociodemographic and clinical data were collected, and the patients underwent clinical evaluation through the Gugging Swallowing Screen (GUSS). RESUL... περισσότερα »
Dysphagia in Patients with Acute Ischemic Stroke: Early Dysphagia Screening May Reduce Stroke-Related Pneumonia and Improve Stroke Outcomes.
*Dysphagia in Patients with Acute Ischemic Stroke: Early Dysphagia Screening May Reduce Stroke-Related Pneumonia and Improve Stroke Outcomes.* Cerebrovasc Dis. 2016 Apr 13;42(1-2):81-89 Authors: Al-Khaled M, Matthis C, Binder A, Mudter J, Schattschneider J, Pulkowski U, Strohmaier T, Niehoff T, Zybur R, Eggers J, Valdueza JM, Royl G, for QugSS II Group Abstract BACKGROUND: Dysphagia is associated with poor outcome in stroke patients. Studies investigating the association of dysphagia and early dysphagia screening (EDS) with outcomes in patients with acute ischemic stroke (AIS) ar... περισσότερα »
Frequency and factors associated with dysphagia in stroke.
*Frequency and factors associated with dysphagia in stroke.* Codas. 2016 Feb;28(1):66-70 Authors: Mourão AM, Lemos SM, Almeida EO, Vicente LC, Teixeira AL Abstract PURPOSE: To investigate the frequency of dysphagia in acute stroke and the possible associated clinical and sociodemographic features. METHOD: A cross-sectional study was performed including 100 stroke patients who were admitted to the Minas Gerais Regional Public Hospital. Sociodemographic and clinical data were collected, and the patients underwent clinical evaluation through the Gugging Swallowing Screen (GUSS). RESUL... περισσότερα »
Condition of Vocal Production-Teacher questionnaire: comparison of responses on Likert scale and visual analog scale.
*Condition of Vocal Production-Teacher questionnaire: comparison of responses on Likert scale and visual analog scale.* Codas. 2016 Feb;28(1):53-58 Authors: Giannini SP, Latorre MD, Ferreira LP Abstract PURPOSE: To compare the responses related to vocal symptoms in two versions of the Vocal Production Condition - Teacher (CPV-T) questionnaire, with responses on a Likert scale and a Visual Analog Scale (VAS), in order to evaluate which is the best measurement method. METHODS: A cross-sectional observational study was conducted with teachers with voice disorders during the period fr... περισσότερα »
Comparison of Cartesian and Non-Cartesian Real-Time MRI Sequences at 1.5T to Assess Velar Motion and Velopharyngeal Closure during Speech.
*Comparison of Cartesian and Non-Cartesian Real-Time MRI Sequences at 1.5T to Assess Velar Motion and Velopharyngeal Closure during Speech.* PLoS One. 2016;11(4):e0153322 Authors: Freitas AC, Wylezinska M, Birch MJ, Petersen SE, Miquel ME Abstract Dynamic imaging of the vocal tract using real-time MRI has been an active and growing area of research, having demonstrated great potential to become routinely performed in the clinical evaluation of speech and swallowing disorders. Although many technical advances have been made in regards to acquisition and reconstruction methodologies... περισσότερα »
Kommerell Diverticulum Should Be Removed in Children With Vascular Ring and Aberrant Left Subclavian Artery.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Kommerell Diverticulum Should Be Removed in Children With Vascular Ring and Aberrant Left Subclavian Artery.* Ann Thorac Surg. 2015 Dec;100(6):2293-7 Authors: Luciano D, Mitchell J, Fraisse A, Lepidi H, Kreitmann B, Ovaert C Abstract BACKGROUND: Right aortic arch with aberrant left subclavian artery is the most frequent cause of vascular ring. Ligamentum arteriosus division opens the ring but leaves the Kommerell diverticulum in place, with a risk of residual compression, aneurysmal dilation, dissection, or even ru... περισσότερα »
Randomised clinical trial: the clinical efficacy and safety of an alginate-antacid (Gaviscon Double Action) versus placebo, for decreasing upper gastrointestinal symptoms in symptomatic gastroesophageal reflux disease (GERD) in China.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Randomised clinical trial: the clinical efficacy and safety of an alginate-antacid (Gaviscon Double Action) versus placebo, for decreasing upper gastrointestinal symptoms in symptomatic gastroesophageal reflux disease (GERD) in China.* Aliment Pharmacol Ther. 2015 Oct;42(7):845-54 Authors: Sun J, Yang C, Zhao H, Zheng P, Wilkinson J, Ng B, Yuan Y Abstract BACKGROUND: There is a paucity of large-scale studies evaluating the clinical benefit of the Gaviscon Double Action (DA) alginate-antacid formulation for treatin... περισσότερα »
Influence of respiratory physiotherapy on gastro-oesophageal reflux in infants: A systematic review.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Influence of respiratory physiotherapy on gastro-oesophageal reflux in infants: A systematic review.* Pediatr Pulmonol. 2015 Sep;50(9):936-44 Authors: Van Ginderdeuren F, Kerckhofs E, Deneyer M, Vanlaethem S, Vandenplas Y Abstract PURPOSE: To provide a survey on the literature concerning the influence of respiratory physiotherapy on gastro-oesophageal reflux (GOR) in infants and young children. METHODS: Electronic databases (Pubmed, Web of Science, PEDro) and reference lists of articles and narrative reviews were ... περισσότερα »
Symptoms of Obstructive Sleep Apnea, Gastroesophageal Reflux and the Risk of Barrett's Esophagus in a Population-Based Case-Control Study.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Symptoms of Obstructive Sleep Apnea, Gastroesophageal Reflux and the Risk of Barrett's Esophagus in a Population-Based Case-Control Study.* PLoS One. 2015;10(6):e0129836 Authors: Lindam A, Kendall BJ, Thrift AP, Macdonald GA, O'Brien S, Lagergren J, Whiteman DC Abstract BACKGROUND: Gastroesophageal reflux is overrepresented in people with obstructive sleep apnea (OSA) and it has been suggested that OSA worsens gastroesophageal reflux symptoms. Aggravated reflux might lead to an increased...περισσότερα »
Caffeine impairs gastrointestinal function in newborn rats.
[image: http:--http://ift.tt/1PAyOTB] Related Articles *Caffeine impairs gastrointestinal function in newborn rats.* Pediatr Res. 2015 Jul;78(1):24-8 Authors: Welsh C, Pan J, Belik J Abstract BACKGROUND: Feeding intolerance is commonly documented in premature infants. Caffeine is routinely utilized for apnea of prematurity treatment and known to reduce the lower esophageal sphincter (LES) muscle tone, but the caffeine effect on the newborn gastrointestinal function is unknown. We hypothesized that caffeine impairs esophageal and gastrointestinal motor function. As such, we investi... περισσότερα »
Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia.* Pediatr Pulmonol. 2015 Jun;50(6):584-7 Authors: Jensen EA, Munson DA, Zhang H, Blinman TA, Kirpalani H Abstract Gastroesophageal reflux may exacerbate lung disease in infants with bronchopulmonary dysplasia (BPD). Anti-reflux surgery may therefore reduce the severity of this disease in some infants. We report a retrospective series of 22 infants with severe BPD who underwent anti-reflux surgery. Our experience indicates that t... περισσότερα »
Frequency and factors associated with dysphagia in stroke.
*Frequency and factors associated with dysphagia in stroke.* Codas. 2016 Feb;28(1):66-70 Authors: Mourão AM, Lemos SM, Almeida EO, Vicente LC, Teixeira AL Abstract PURPOSE: To investigate the frequency of dysphagia in acute stroke and the possible associated clinical and sociodemographic features. METHOD: A cross-sectional study was performed including 100 stroke patients who were admitted to the Minas Gerais Regional Public Hospital. Sociodemographic and clinical data were collected, and the patients underwent clinical evaluation through the Gugging Swallowing Screen (GUSS). RESUL... περισσότερα »
Dysphagia in Patients with Acute Ischemic Stroke: Early Dysphagia Screening May Reduce Stroke-Related Pneumonia and Improve Stroke Outcomes.
*Dysphagia in Patients with Acute Ischemic Stroke: Early Dysphagia Screening May Reduce Stroke-Related Pneumonia and Improve Stroke Outcomes.* Cerebrovasc Dis. 2016 Apr 13;42(1-2):81-89 Authors: Al-Khaled M, Matthis C, Binder A, Mudter J, Schattschneider J, Pulkowski U, Strohmaier T, Niehoff T, Zybur R, Eggers J, Valdueza JM, Royl G, for QugSS II Group Abstract BACKGROUND: Dysphagia is associated with poor outcome in stroke patients. Studies investigating the association of dysphagia and early dysphagia screening (EDS) with outcomes in patients with acute ischemic stroke (AIS) ar... περισσότερα »
Randomised clinical trial: the clinical efficacy and safety of an alginate-antacid (Gaviscon Double Action) versus placebo, for decreasing upper gastrointestinal symptoms in symptomatic gastroesophageal reflux disease (GERD) in China.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Randomised clinical trial: the clinical efficacy and safety of an alginate-antacid (Gaviscon Double Action) versus placebo, for decreasing upper gastrointestinal symptoms in symptomatic gastroesophageal reflux disease (GERD) in China.* Aliment Pharmacol Ther. 2015 Oct;42(7):845-54 Authors: Sun J, Yang C, Zhao H, Zheng P, Wilkinson J, Ng B, Yuan Y Abstract BACKGROUND: There is a paucity of large-scale studies evaluating the clinical benefit of the Gaviscon Double Action (DA) alginate-antacid formulation for treati... περισσότερα »
Influence of respiratory physiotherapy on gastro-oesophageal reflux in infants: A systematic review.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Influence of respiratory physiotherapy on gastro-oesophageal reflux in infants: A systematic review.* Pediatr Pulmonol. 2015 Sep;50(9):936-44 Authors: Van Ginderdeuren F, Kerckhofs E, Deneyer M, Vanlaethem S, Vandenplas Y Abstract PURPOSE: To provide a survey on the literature concerning the influence of respiratory physiotherapy on gastro-oesophageal reflux (GOR) in infants and young children. METHODS: Electronic databases (Pubmed, Web of Science, PEDro) and reference lists of articles and narrative reviews were... περισσότερα »
Symptoms of Obstructive Sleep Apnea, Gastroesophageal Reflux and the Risk of Barrett's Esophagus in a Population-Based Case-Control Study.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Symptoms of Obstructive Sleep Apnea, Gastroesophageal Reflux and the Risk of Barrett's Esophagus in a Population-Based Case-Control Study.* PLoS One. 2015;10(6):e0129836 Authors: Lindam A, Kendall BJ, Thrift AP, Macdonald GA, O'Brien S, Lagergren J, Whiteman DC Abstract BACKGROUND: Gastroesophageal reflux is overrepresented in people with obstructive sleep apnea (OSA) and it has been suggested that OSA worsens gastroesophageal reflux symptoms. Aggravated reflux might lead to an increase...περισσότερα »
Caffeine impairs gastrointestinal function in newborn rats.
[image: http:--http://ift.tt/1PAyOTB] Related Articles *Caffeine impairs gastrointestinal function in newborn rats.* Pediatr Res. 2015 Jul;78(1):24-8 Authors: Welsh C, Pan J, Belik J Abstract BACKGROUND: Feeding intolerance is commonly documented in premature infants. Caffeine is routinely utilized for apnea of prematurity treatment and known to reduce the lower esophageal sphincter (LES) muscle tone, but the caffeine effect on the newborn gastrointestinal function is unknown. We hypothesized that caffeine impairs esophageal and gastrointestinal motor function. As such, we invest... περισσότερα »
Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia.* Pediatr Pulmonol. 2015 Jun;50(6):584-7 Authors: Jensen EA, Munson DA, Zhang H, Blinman TA, Kirpalani H Abstract Gastroesophageal reflux may exacerbate lung disease in infants with bronchopulmonary dysplasia (BPD). Anti-reflux surgery may therefore reduce the severity of this disease in some infants. We report a retrospective series of 22 infants with severe BPD who underwent anti-reflux surgery. Our experience indicates that ... περισσότερα »
Frequency and factors associated with dysphagia in stroke.
*Frequency and factors associated with dysphagia in stroke.* Codas. 2016 Feb;28(1):66-70 Authors: Mourão AM, Lemos SM, Almeida EO, Vicente LC, Teixeira AL Abstract PURPOSE: To investigate the frequency of dysphagia in acute stroke and the possible associated clinical and sociodemographic features. METHOD: A cross-sectional study was performed including 100 stroke patients who were admitted to the Minas Gerais Regional Public Hospital. Sociodemographic and clinical data were collected, and the patients underwent clinical evaluation through the Gugging Swallowing Screen (GUSS). RESUL... περισσότερα »
Dysphagia in Patients with Acute Ischemic Stroke: Early Dysphagia Screening May Reduce Stroke-Related Pneumonia and Improve Stroke Outcomes.
*Dysphagia in Patients with Acute Ischemic Stroke: Early Dysphagia Screening May Reduce Stroke-Related Pneumonia and Improve Stroke Outcomes.* Cerebrovasc Dis. 2016 Apr 13;42(1-2):81-89 Authors: Al-Khaled M, Matthis C, Binder A, Mudter J, Schattschneider J, Pulkowski U, Strohmaier T, Niehoff T, Zybur R, Eggers J, Valdueza JM, Royl G, for QugSS II Group Abstract BACKGROUND: Dysphagia is associated with poor outcome in stroke patients. Studies investigating the association of dysphagia and early dysphagia screening (EDS) with outcomes in patients with acute ischemic stroke (AIS) ar... περισσότερα »
Dysphagia and anorexia as presentations of leptomeningeal carcinomatosis.
Related Articles *Dysphagia and anorexia as presentations of leptomeningeal carcinomatosis.* BMJ Case Rep. 2016;2016 Authors: Aiyer R, Engelman E, Xue W, Yu E Abstract A 61-year-old woman presented to the emergency department, with a 4-day history of isolated oropharyngeal dysphagia associated with anorexia and weight loss over the previous 4 weeks. She had no other focal neurological symptoms and no deficits on examination. She had been in a 4-year remission of breast cancer postmastectomy and chemoradiation. Neuroimaging showed enhancement of cranial nerves VII, VIII, cisternal...περισσότερα »
A Review of the Potential Pathogenicity and Management Of Frequent Premature Ventricular Contractions.
Related Articles *A Review of the Potential Pathogenicity and Management Of Frequent Premature Ventricular Contractions.* Pacing Clin Electrophysiol. 2016 Apr 13; Authors: Laplante L, Benzaquen BS Abstract Very frequent premature ventricular complexes (PVC's) may be a reversible cause of dilated cardiomyopathy. Literature on this largely unrecognized entity has increased in the last fifteen years. This paper reviews the literature on the consequences of frequent PVCs on myocardial function and management of PVC associated cardiomyopathy. The authors reviewed articles published i... περισσότερα »
Prediction of survival prognosis of non-small cell lung cancer by APE1 through regulation of Epithelial-Mesenchymal Transition.
*Prediction of survival prognosis of non-small cell lung cancer by APE1 through regulation of Epithelial-Mesenchymal Transition.* Oncotarget. 2016 Apr 8; Authors: Wei X, Li Q, Li Y, Duan W, Huang C, Zheng X, Sun L, Luo J, Wang D, Zhang S, Xin X, Gao M Abstract The DNA base excision repair gene APE1 involves in DNA damage repair pathway and overexpression in a variety of human cancers. Analyses of patients with non-small cell lung cancer (NSCLC) suggested that multiple factors associated with prognosis of NSCLC patients. Further investigation showed that APE1 expression was able t... περισσότερα »
ProNGF is a potential diagnostic biomarker for thyroid cancer.
*ProNGF is a potential diagnostic biomarker for thyroid cancer.* Oncotarget. 2016 Apr 8; Authors: Faulkner S, Roselli S, Demont Y, Pundavela J, Choquet G, Leissner P, Oldmeadow C, Attia J, Walker MM, Hondermarck H Abstract The precursor for nerve growth factor (proNGF) is expressed in some cancers but its clinicopathological significance is unclear. The present study aimed to define the clinicopathological significance of proNGF in thyroid cancer. ProNGF expression was analysed by immunohistochemistry in two cohorts of cancer versus benign tumors (adenoma) and normal thyroid tiss...περισσότερα »
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