Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Δευτέρα 25 Απριλίου 2016

OtoRhinoLaryngology & Medicine,New Articles,April 25th,2016,a


miRNA-expression and clinical tumour parameters in oral squamous cell carcinoma (OSCC)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Evaluation of via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 22 April 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): J. Moratin, S. Hartmann, R. Brands, M. Brisam, G. Mutzbauer, C. Scholz, A. Seher, U. Müller-Richter, A.C. Kübler, C. Linz Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most common malignancy worldwide. The past decades have not led to substantial improvement in diagnosis and therapy. Analysis of miRNA expression may help to determine the progression profiles and outcomes of m...περισσότερα »

Rosuvastatin on calvarial bone healing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
The influence of oral administration of rosuvastatin on calvarial bone healing in rats via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 22 April 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Akif Türer, Çiğdem Coşkun Türer, M. Cenk Durmuşlar, Umut Balli, M. Emin Önger The purpose of this study is to investigate the potential of the systemic administration of different doses of rosuvastatin (RSV) on autogenous grafted critical-sized cortical bone defects. Twenty-four rats were divided into three groups: Group C ... περισσότερα »

Reduction malarplasty

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
External radiopaque marking of Gillies posterior zygomatic arch osteotomy in reduction malarplasty via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 22 April 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Sae Bin Lee, Jun Hyuk Lee, Hyun Jin Min Although the Gillies (temporal) approach to reduction malarplasty helps preserve supportive soft tissue and avoid facial scars, the osteotomy site is difficult to gauge when using this blind technique. Our experience with external radiopaque marking of the zygomatic arch to... περισσότερα »

Radiotherapy for oral cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
decreases the cutaneous expression of host defence peptides via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 22 April 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): S. Koerdt, L. Steinstraesser, M. Stoeckelhuber, C.J. Wales, N.H. Rohleder, G. Babaryka, T. Steiner, K.-D. Wolff, D.J. Loeffelbein, T. Muecke, M. Nieberler, M.R. Kesting IntroductionBacterial resistance against antibiotics has become an increasing challenge in the treatment of cutaneous infections. Consequences can be severe, especially in infected wo...περισσότερα »

Gastric bezoar after Roux-en-Y gastric bypass for morbid obesity: A case report.

Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Gastric bezoar after Roux-en-Y gastric bypass for morbid obesity: A case report.* Int J Surg Case Rep. 2016 Apr 21;23:112-115 Authors: Ertugrul I, Tardum Tardu A, Tolan K, Kayaalp C, Karagul S, Kirmizi S Abstract INTRODUCTION: We aimed to present a patient with gastric pouch bezoar after having a bariatric surgery. PRESENTATION OF CASE: Sixty-three years old morbid obese female had a laparoscopic Roux-en-Y gastric bypass surgery 14 months ago. She has lost 88% of her excess body mass index; but started to suffer from nausea, abdominal distention and vomiting lately, especially f... περισσότερα »

A case report of total breast reconstruction using an inframammary adipofascial flap with an implant.

Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*A case report of total breast reconstruction using an inframammary adipofascial flap with an implant.* Int J Surg Case Rep. 2016 Apr 13;23:109-111 Authors: Ogawa T, Yamakawa T Abstract INTRODUCTION: Prosthetic-based breast reconstruction can be used in combination with autologous flaps such as a latissimus dorsi (LD) flap or a thoracodorsal artery perforator (TDAP) flap to achieve symmetry. However, the LD and TDAP flaps require a different skin incision from that which is used for the mastectomy. As a new autologous flap for use in combination with prosthetic-based breast recon... περισσότερα »

Ensemble Structure of the Highly Flexible Complex Formed between Vesicular Stomatitis Virus Unassembled Nucleoprotein and its Phosphoprotein Chaperone.

Alexandros G. SfakianakisστοHead and NeckΠριν από 5 δευτερόλεπτα
*Ensemble Structure of the Highly Flexible Complex Formed between Vesicular Stomatitis Virus Unassembled Nucleoprotein and its Phosphoprotein Chaperone.* J Mol Biol. 2016 Apr 20; Authors: Yabukarksi F, Leyrat C, Martinez N, Communie G, Ivanov I, Ribeiro EA, Buisson M, Gerard FC, Bourhis JM, Jensen MR, Bernadó P, Blackledge M, Jamin M Abstract Nucleocapsid assembly is an essential process in the replication of the non-segmented, negative-sense RNA viruses (NNVs). Unassembled nucleoprotein (N(0)) is maintained in an RNA-free and monomeric form by its viral chaperone, the phosphopr... περισσότερα »

Xenogenic bovine bone grafting

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Can one-wall bone defects be augmented with xenogenic bone grafting material alone? via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 22 April 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Christian Mehl, Matthias Kern, Niclas Meinke, Yahya Açil, Telse Bähr, Jörg Wiltfang, Volker Gaßling ObjectivesThe main aim of this study was to evaluate the impact of xenogenic bovine bone grafting material particle size, addition of harvested autogenic bone as well as the influence of a periosteum on growth of newly formed bo...περισσότερα »

Poly(ɛ-caprolactone)/calcium phosphate ceramic composite for craniomaxillofacial fracture fixation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
A self-reinforcing biodegradable implant made of via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 22 April 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Chang-Chin Wu, Yuh-Feng Tsai, Li-Ho Hsu, Jo-Ping Chen, Shoichiro Sumi, Kai-Chiang Yang PurposeBiodegradable polymer fixators have been used widely in oral and maxillofacial surgery for fracture management. However, short-comings such as insufficient mechanical strength, inappropriate degradation time, lack of radiolucency, and foreign body reactions during bone...περισσότερα »

Le Fort 1 osteotomy and calvarial bone grafting

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
for severely resorbed maxillae via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 22 April 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): M. Schlund, R. Nicot, L. Lauwers, G. Raoul, J. Ferri IntroductionLong standing maxillary edentulism leads to alveolar ridge resorption which prevent implant placement and causes prosthetic malocclusion. The aim of the study was to assess vertical and transversal bone increase following Le Fort 1 osteotomy associated with calvarial bone grafting.Materials and Methods66 patients w... περισσότερα »

Comparative histology of some craniofacial sutures and skull-base synchondroses in non-avian dinosaurs and their extant phylogenetic bracket

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 7 δευτερόλεπτα
Abstract Sutures and synchondroses, the fibrous and cartilaginous articulations found in the skulls of vertebrates, have been studied for many biological applications at the morphological scale. However, little is known about these articulations at the microscopic scale in non-mammalian vertebrates, including extant archosaurs (birds and crocodilians). The major goals of this paper were to: (i)… Continue reading Comparative histology of some craniofacial sutures and skull-base synchondroses in non-avian dinosaurs and their extant phylogenetic bracket

IJMS, Vol. 17, Pages 602: The Opposite Effect of Metal Ions on Short-/Long-Range Water Structure: A Multiple Characterization Study

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 7 δευτερόλεπτα
Inorganic electrolyte solutions are very important in our society as they dominate many biochemical and geochemical processes. Herein, an in-depth study was performed to illustrate the ion-induced effect on water structure by coupling NMR, viscometer, Raman and Molecular Dynamic (MD) simulations. The NMR coefficient (BNMR) and diffusion coefficient (D) from NMR, and viscosity coefficient (Bvis)… Continue reading IJMS, Vol. 17, Pages 602: The Opposite Effect of Metal Ions on Short-/Long-Range Water Structure: A Multiple Characterization Study

Comparative histology of some craniofacial sutures and skull-base synchondroses in non-avian dinosaurs and their extant phylogenetic bracket

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 7 δευτερόλεπτα
Abstract Sutures and synchondroses, the fibrous and cartilaginous articulations found in the skulls of vertebrates, have been studied for many biological applications at the morphological scale. However, little is known about these articulations at the microscopic scale in non-mammalian vertebrates, including extant archosaurs (birds and crocodilians). The major goals of this paper were to: (i)… Continue reading Comparative histology of some craniofacial sutures and skull-base synchondroses in non-avian dinosaurs and their extant phylogenetic bracket

Are SOFT and TEXT results practice changing and how?

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 7 δευτερόλεπτα
Authors: Pagani O, Regan MM, Francis PA Abstract Optimal adjuvant endocrine therapy for premenopausal women with hormone-receptor positive breast cancer has long been debated. In particular, the role of ovarian function suppression in addition to standard tamoxifen divided oncologists worldwide, and more recently, the role of aromatase inhibitors as an alternative to tamoxifen in the… Continue reading Are SOFT and TEXT results practice changing and how?

Synthesis of New Alkylated Mononucleotide Analogues and Their Repair Proficiency by the Prokaryotic DNA Repair Protein AlkB

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 7 δευτερόλεπτα
We describe the synthesis of a variety of new alkylated mononucleotides and examine their repair proficiency with the prokaryotic direct DNA repair protein AlkB. A comparison of rates of repair among the different substrates supports the currently accepted radical mechanism. from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1QwK2E5 via IFTTT

Ultrasonic and sonic devices for osseous surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Micromorphometric analysis of bone blocks harvested with eight different ultrasonic and sonic devices for osseous surgery via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 22 April 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Claudio Stacchi, Federico Berton, Gianluca Turco, Maurizio Franco, Chiara Ottavia Navarra, Francesca Andolsek, Michele Maglione, Roberto Di Lenarda ObjectivesThe aim of this study was to analyse in vitro the main features of osteotomies performed by means of different ultrasonic and sonic s...περισσότερα »

Children with craniosynostosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Parental perception of treatment and medical care in via Oral and Maxillofacial Surgery Publication date: Available online 23 April 2016 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): S. Kluba, S. Rohleder, M. Wolff, K. Haas-Lude, M.U. Schuhmann, B.E. Will, S. Reinert, M. Krimmel Surgery for craniosynostosis implies a relevant strain on the child and the parents. The development of the child's self-perception and self-confidence is mainly influenced by parental attitudes. The outcomes of 46 patients were analysed, taking into consideration parental percept... περισσότερα »

Imaging Features of Medicine-Related Osteonecrosis of the Jaws

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
: Comparison between Panoramic Radiograph and Computed Tomography via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 22 April 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Yuxing Guo, Diancan Wang, Yang Wang, Xin Peng, Chuanbin Guo ObjectiveThe current staging system of Medicine-Related Osteonecrosis of the Jaws (MRONJ) assigns patients to different stages based on clinical manifestations. The extent of bone disease could not be fully reflected without the radiologic evaluation. This missing info... περισσότερα »

3D measurements of the upper airway on CBCT images

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
Reliability of three-dimensional via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 23 April 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Hui Chen, Ghizlane Aarab, Azin Parsa, Jan de Lange, Paul F. van der Stelt, Frank Lobbezoo Objectives(1) to assess intra- and inter-observer reliability of the localization of anatomical landmarks of the upper airway on cone beam computed tomography (CBCT) images; (2) and to assess intra- and inter-observer reliability of the three-dimensional measurements of ...περισσότερα »

Biomarkers for sporadic Creutzfeldt–Jakob disease

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 10 δευτερόλεπτα
Abstract Sporadic Creutzfeldt–Jakob disease (sCJD) is a rare but fatal type of spongiform encephalopathy with unknown cause. Unfortunately, definitive diagnosis of this disease can only be done by examination of postmortem brain tissue. Presumptive diagnosis is done through a combination of clinical manifestations, radiology results, and cerebrospinal fluid (CSF) testing for CSF 14-3-3. Even with these guidelines, premortem diagnosis of sCJD can be unreliable with high rates of misdiagnosis. This calls for more reliable biomarkers of the disease, allowing for better diagnosis as we... περισσότερα »

Comparative histology of some craniofacial sutures and skull-base synchondroses in non-avian dinosaurs and their extant phylogenetic bracket

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Abstract Sutures and synchondroses, the fibrous and cartilaginous articulations found in the skulls of vertebrates, have been studied for many biological applications at the morphological scale. However, little is known about these articulations at the microscopic scale in non-mammalian vertebrates, including extant archosaurs (birds and crocodilians). The major goals of this paper were to: (i) document the microstructure of some sutures and synchondroses through ontogeny in archosaurs; (ii) compare these microstructures with previously published sutural histology (i.e. that of ma... περισσότερα »

Influence of Anatomic Position and Intraoperative Exposure of the Inferior Alveolar Nerve on Neurosensory Disturbance

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
After Sagittal Split Ramus Osteotomy: A Three-Dimensional Computed Tomography Study via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 23 April 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Jee Ho Lee, Young Jin Son, Jong Hyun Hwang, Seung Hee Baek, Ju Hong Jeon ObjectiveTo evaluate the influence of the anatomic position and intraoperative exposure of inferior alveolar nerve on neurosensory disturbance (NSD) in sagittal split ramus osteotomy (SSRO).Study DesignThe anatomic factors of the nerve...περισσότερα »

PET/CT scanning as a detector of high-risk patients with oral infection during preoperative staging

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
The potential of Positron emission tomography/computerized tomography via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 22 April 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Keisuke Yamashiro, Makoto Nakano, Koichi Sawaki, Fumihiko Okazaki, Yasuhisa Hirata, Shogo Takashiba ObjectiveIt is sometimes difficult for physicians to determine during the intraoperative period whether patients have oral infections; the patients need treatment for preventing oral infection-related complications during ...περισσότερα »

Primary closure and skin grafts of the free fibula osteocutaneous flap donor site

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Comparison between via Oral Maxillofac Surg AbstractPurposeThis study aimed to compare the size of skin paddles, the postoperative course, and donor site complications between primary closure and skin grafts of the free fibula flap donor site. MethodsThirty-five consecutive patients were enrolled. Medical records were retrospectively reviewed for risk factors for delayed healing, size of skin paddles, time to resumption of gait with a mobility aid and self-ambulation, early donor site morbidity, and late donor site complaints. ResultsThe harvested skin paddles were significantly wider... περισσότερα »

Recombinant Human Bone Morphogenetic Protein-2 in Localized Alveolar Ridge and Maxillary Sinus Augmentation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Systematic Review and Meta-Analysis of via Oral and Maxillofacial Surgery Publication date: May 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 5 Author(s): Mick P. Kelly, Olushola L. Akinshemoyin Vaughn, Paul A. Anderson PurposeRecombinant human bone morphogenetic protein-2 (rhBMP-2) is approved by the Food and Drug Administration as a viable alternative to bone graft in spinal fusion and maxillary sinus lift. The research questions for meta-analysis were: Is rhBMP-2 an effective bone graft substitute in localized alveolar ridge augmentation and maxillary sin...περισσότερα »

AMD3100 Attenuates Matrix Metalloprotease-3 and -9 Expressions and Prevents Cartilage Degradation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
in a Monosodium Iodo-Acetate–Induced Rat Model of Temporomandibular Osteoarthritis via Oral and Maxillofacial Surgery Publication date: May 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 5 Author(s): Xiao-yan Wang, Yan Chen, Xue-jiao Tang, Lin-hong Jiang, Ping Ji PurposeTemporomandibular joint osteoarthritis (TMJOA) is an important subtype of temporomandibular disorder. This study investigated the inflammatory role of the stromal cell-derived factor-1 (SDF-1) and C-X-C chemokine receptor-4 (CXCR4) axis and the probable signaling pathway involved in matrix me...περισσότερα »

The Management of Zygomaticomaxillary Complex Fractures

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Does Training Background Influence Decision-Making in the Management of Zygomaticomaxillary Complex Fractures? via Oral and Maxillofacial Surgery Publication date: May 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 5 Author(s): Srinivas M. Susarla, Gerhard S. Mundinger, Devin O'Brien-Coon, Thomas B. Dodson, Paul N. Manson, Zachary S. Peacock, Amir H. Dorafshar PurposeManagement of zygomaticomaxillary complex (ZMC) fractures should be based on injury patterns and not on training background. This study assessed management decisions for ZMC injuries among surgeon... περισσότερα »

Central and Peripheral Giant Cell Lesions of the Jaws

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Immunoexpression of Glucose Transporters 1 and 3 and Macrophage Colony-Stimulating Factor in via Oral and Maxillofacial Surgery Publication date: May 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 5 Author(s): Rodrigo Gadelha Vasconcelos, Felipe Rodrigues de Matos, Marcelo Gadelha Vasconcelos, Anderson Nicolly Fernandes da Costa, Lélia Maria Guedes Queiroz PurposeThe peripheral giant cell lesion (PGCL) is a reactive process associated with a local irritating factor that shows low recurrence after treatment, especially if the irritating factor is eliminated. ... περισσότερα »

Soft Tissue Changes Around the Lips After Mandibular Setback Surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Evaluation of Soft Tissue Changes Around the Lips After Mandibular Setback Surgery With Minimal Orthodontics Using Three-Dimensional Stereophotogrammetry via Oral and Maxillofacial Surgery Publication date: May 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 5 Author(s): Young-Kyun Kim, Sang-Woon Moon, Pil-Young Yun, You-Sun Lee, Brent E. Larson, Nam-Ki Lee PurposeMost reports on the surgery-first approach in skeletal Class III malocclusion have focused on the skeletal changes. The present study evaluated the soft tissue changes around the lips over time after...περισσότερα »

Synovial Cell Sarcoma of the Head and Neck

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Factors Associated With Survival in Patients With Synovial Cell Sarcoma of the Head and Neck: An Analysis of 167 Cases Using the SEER (Surveillance, Epidemiology, and End Results) Database JAMA Otolaryngol Head Neck Surg. 2016 Apr 21; Authors: Mallen-St Clair J, Arshi A, Abemayor E, St John M Abstract Importance: Synovial cell sarcoma of the head and neck (SCSHN) is a rare tumor associated with significant morbidity and mortality. The literature regarding these tumors is limited to case series and case reports. We used data from the population-based US Surveillance, Epidemiology, a...περισσότερα »

Chronic respiratory failure due to toxic epidermal necrosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
[image: http:--www.tandfonline.com-templates-jsp] *Chronic respiratory failure due to toxic epidermal necrosis in a 10 year old girl.* Acta Clin Belg. Authors: Thimmesch M, Gilbert A, Tuerlinckx D, Bodart E Abstract Toxic epidermal necrosis is a severe mucocutaneous disease with a high mortality rate. A third of the patients surviving the acute phase will develop pulmonary complications. The most frequent complication is bronchiolitis obliterans. Despite well-conducted treatment, in most cases, lung injury often leads to chronic respiratory failure. We describe here the case of... περισσότερα »

Citronella and cinnamon essential oils on Candida albicans biofilms

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Efficacy of Acta Odontol Scand. 2016 Apr 21;:1-6 Authors: Almeida LF, Paula JF, Almeida RV, Williams DW, Hebling J, Cavalcanti YW Abstract INTRODUCTION: The discovery of new antimicrobials derived from plants could aid in the management of biofilm-associated infections, including denture-induced stomatitis (DS). DS is an oral infection caused by Candida biofilms on the surfaces of poorly cleansed dentures. Effective treatment of DS requires the use of an appropriate denture cleanser and preferably one that exhibits antimicrobial properties. OBJECTIVE: This study aimed to evaluat...περισσότερα »

A Genomic Alternative to Identify Medullary Thyroid Cancer Preoperatively in Thyroid Nodules with Indeterminate Cytology

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
A Genomic Alternative to Identify Medullary Thyroid Cancer Preoperatively in Thyroid Nodules with Indeterminate Cytology: Thyroid , Vol. 0, No. 0. Author information Richard T. Kloos,1 Robert J. Monroe,2 S. Thomas Traweek,3 Richard B. Lanman, 1† and Giulia C. Kennedy4 1Department of Medical Affairs, Veracyte, Inc., South San Francisco, California. 2CLIA, Veracyte, Inc., South San Francisco, California. 3Thyroid Cytopathology Partners, Austin, Texas. 4Department of Research and Development, Veracyte, Inc., South San Francisco, California. †*Current address*: Department of Medical Affa...περισσότερα »

Hereditary Risk Factors for Thyroid Cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Hereditary Risk Factors for Thyroid Cancer: *Condition*: Thyroid Cancer *Intervention*: Other: Collection of family and medical history, and blood or saliva sample for genetic studies *Sponsor*: Dana-Farber Cancer Institute Groups/CohortsAssigned Interventions Individuals with past or present thyroid cancer/nodules Any individual who has or had a thyroid cancer or nodule either in childhood or suspected to be part of an inherited syndrome Other: Collection of family and medical history, and blood or saliva sample for genetic studies Family members of individuals with thyroid c...περισσότερα »

Effect of COX-2 and EGFR Suppression on Molecular Markers of Angiogenesis and Proliferation in Squamous Cell Carcinoma of Oral Cavity

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
- Prospective Randomized Study: *Conditions*: Oral Squamous Cell Carcinoma; Carcinoma of Buccal Mucosa; Tongue Cancers; Head and Neck Cancers *Interventions*: Drug: Celecoxib; Drug: Erlotinib; Drug: Celecoxib + Erlotinib *Sponsor*: Tata Memorial Hospital ArmsAssigned Interventions Experimental: Arm 1 Celecoxib 200mg twice daily for 21 days Drug: Celecoxib Drug given orally for 21 days after confirmation by biopsy and before definitive treatment by surgery Experimental: Arm 2 Celecoxib 200 mg twice daily for 21 days and Erlotinib 150 mg once daily for 21 days Drug:... περισσότερα »

Rate discrimination, gap detection and ranking of temporal pitch

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
in cochlear implant users via Journal of the Association for Research in Otolaryngology AbstractCochlear implant (CI) users have poor temporal pitch perception, as revealed by two key outcomes of rate discrimination tests: (i) rate discrimination thresholds (RDTs) are typically larger than the corresponding frequency difference limen for pure tones in normal hearing listeners, and (ii) above a few hundred pulses per second (i.e. the “upper limit” of pitch), CI users cannot discriminate further increases in pulse rate. Both RDTs at low rates and the upper limit of pitch vary across l... περισσότερα »

Intrasphenoid septations inserted into the internal carotid arteries

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
: a frequent and risky relationship in transsphenoidal surgeries via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 22 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Clauder Oliveira Ramalho, Horacio Armando Marenco, Francisco de Assis Vaz Guimarães Filho, Marcos Devanir Silva da Costa, Bruno Fernandes de Oliveira Santos, Rodrigo de Paula Santos, Samuel Tau Zymberg IntroductionWhen an expanded endonasal transsphenoidal surgical approach is performed, intrasphenoid septations must be completely resected. If t... περισσότερα »

Sinusitis in patients undergoing allogeneic bone marrow transplantation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
– a review via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Joanna Ewa Drozd-Sokolowska, Jacek Sokolowski, Wieslaw Wiktor-Jedrzejczak, Kazimierz Niemczyk IntroductionSinusitis is a common morbidity in general population, however little is known about its occurrence in severely immunocompromised patients undergoing allogeneic hematopoietic stem cell transplantation.ObjectiveThe aim of the study was to analyze the literature concerning sinusitis in patients undergoing allogeneic bone marrow transplantat...περισσότερα »

Conductive hearing loss on central auditory function

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
Effect of via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 22 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Arash Bayat, Mohammad Farhadi, Hesam Emamdjomeh, Ahmad Daneshi, Golshan Mirmomeni IntroductionIt has been demonstrated that long-term Conductive Hearing Loss (CHL) may influence the precise detection of the temporal features of acoustic signals or Auditory Temporal Processing (ATP). It can be argued that ATP may be the underlying component of many central auditory processing capabilities such as ...περισσότερα »

Bacteria Pseudomonas aeruginosa and MRSA associated with chronic suppurative otitis media (CSOM)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
Surveillance of via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 22 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Sibanarayan Rath, Saumya R. Das, Rabindra Nath Padhy IntroductionSuppurative otitis media is a critical disease causing perforation of the tympanic membrane associated with changes of the mucoperiosteum of the middle ear cleft.ObjectiveTo isolate causative bacteria from chronic suppurative ear discharges and to ascertain their antibiotic profiles, of patients attending outpatients department... περισσότερα »

Success of free flap anastomoses performed within the zone of trauma in acute lower limb reconstruction.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα
*Success of free flap anastomoses performed within the zone of trauma in acute lower limb reconstruction.* J Plast Reconstr Aesthet Surg. 2016 Mar 10; Authors: Bendon CL, Giele HP Abstract Traditionally, in free flap cover of lower limb injuries, every attempt is made to perform anastomoses proximal to the zone of injury. We report on the success of anastomoses within the zone of trauma, at the level of the fracture, avoiding further dissection and exposure. The records of free flap reconstructions for fractures of the lower extremity at a tertiary trauma centre between 2004 and ... περισσότερα »

Surgical treatment of choanal atresia with transnasal endoscopic approach with stentless single side-hinged flap technique

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
: 5 year retrospective analysis via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Saraniti Carmelo, Santangelo Manuela, Salvago Pietro IntroductionChoanal atresia is a rare congenital malformation of the nasal cavity characterized by the complete obliteration of the posterior choanae. In the 67% of cases choanal atresia is unilateral, affecting mainly (71%) the right nasal cavity. Differently from the unilateral form, bilateral choanal atresia is a life-threatening condition often associated with respir... περισσότερα »

Ozone therapy on facial nerve regeneration

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Effects of via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 22 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Isa Ozbay, Ilker Ital, Cuneyt Kucur, Raziye Akcılar, Aysenur Deger, Savas Aktas, Fatih Oghan IntroductionOzone may promote moderate oxidative stress, which increases antioxidant endogenous systems. There are a number of antioxidants that have been investigated therapeutically for improving peripheral nerve regeneration. However, no previous studies have reported the effect of ozone therapy on fa...περισσότερα »

Sublingual immunotherapy on platelet activity in children with allergic rhinitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Effect of via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 22 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Yanqiu Chen, Lifeng Zhou, Yan Yang IntroductionThe role of platelet activation in allergic inflammation received increasing attention. Sublingual immunotherapy (SLIT) for allergic rhinitis (AR) can modify the immunological process to an allergen, rather than treating symptoms simply.ObjectiveThe aim of this study was to explore the role of platelet activation during SLIT in children with AR.Metho... περισσότερα »

Patients with hearing loss genotyped for the connexin 26 gene (GJB2) mutations

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Evaluation of electrocardiographic parameters in via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Agnieszka Sanecka, Elzbieta Katarzyna Biernacka, Magdalena Sosna, Malgorzata Mueller-Malesinska, Rafal Ploski, Henryk Skarzynski, Ryszard Piotrowicz IntroductionSeveral studies have associated congenital sensorineural hearing loss in children with prolongation of the cardiac parameter QTc. The cause of this association is unknown. At the same time, mutations in GJB2, which encodes connexin 26, are the mos...περισσότερα »

Treatment of ossicular lesions without reconstruction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
– our explanation for seven cases via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Introduction The ossicular chain function is well known since mid-19th century. Its presence promotes a sound amplification of about 30 dB. Therefore, one can expect its interruption originates an air-bone gap of about 30 dB or more. This discontinuity, represented mainly by erosion of the incus, is commonly encountered in chronic otitis media or, more rarely, in middle ear trauma, either as a consequence of the disease itself or produced by surgical procedures. In many instances... περισσότερα »

Congenital neck cyst originated from ultimobranchial body

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
* in a fetus* *via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology* Introduction *There are increasing evidence of detection in structural abnormality that influence on the prenatal treatment and prognosis using intrauterine ultrasonography. Intrauterine ultrasonography has contributed to the increasing detection of structural abnormality in fetuses, which has influence on the prenatal treatment and prognosis.* *The role of prenatal ultrasonography in the fetal neck mass is to observe the size and position change of the mass through echogenicity continuously and to... περισσότερα »

Nasal polyps with and without eosinophilia

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Distinct characteristics of via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 22 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Changzhi Sun, Hong Ouyang, Renzhong Luo IntroductionEosinophilic and noneosinophilic NPs are different subtypes of NPs and require different treatment methods.ObjectivesTo compare the histologic characteristics, mRNA and protein expression between Nasal Polyps (NPs) with and without eosinophilia.MethodsNPs tissues were obtained from eighty-six NPs patients during surgery. Eosinop...περισσότερα »

Synchronous multiple unilateral parotid gland tumors of benign and malignant histological types

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
*: case report and literature review* *via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology* *Source:Brazilian Journal of OtorhinolaryngologyAuthor(s): Aleksandra Ochal-Choińska, Antoni Bruzgielewicz, Ewa Osuch-Wójcikiewicz* Introduction *Salivary gland tumors are a very heterogeneous group of lesions. According to the histological classification published by WHO in 2005, 10 types of benign and 24 types of malignant tumors of the salivary glands can be distinguished. All of these lesions are relatively rare, and represent only 3–4% of head and neck tumors. 80% of t... περισσότερα »

Repeated Dix-Hallpike and roll maneuvers

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Diagnostic value of repeated Dix-Hallpike and roll maneuvers in benign paroxysmal positional vertigo via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 22 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Cenk Evren, Nevzat Demirbilek, Mustafa Suphi Elbistanlı, Füruzan Köktürk, Mustafa Çelik IntroductionBenign Paroxysmal Positional Vertigo (BPPV) is the most common peripheral vestibular disorder. The Dix-Hallpike and Roll maneuvers are used to diagnose BPPV.ObjectiveThis study aims to investigate the diagnost...περισσότερα »

Giant peripheral osteoma of the mandible

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
simulating a parotid gland tumor via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology [image: Panoramic X-ray view showing a radiopaque lesion located in the middle of the ...] [image: Three-dimensional image showing a perfectly delimited lesion of exophytic benign ...] [image: Axial computed tomography scan showing the lesion to extend toward the internal ...] *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Javier Ata-Ali, Fadi Ata-Ali

HPV infection

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
HPV and students in Brazil: an assessment of knowledge of a common infection – preliminary report via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 22 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): João Cesar Frizzo Burlamaqui, Ana Carolina Cassanti, Gabriela Bastos Borim, Edward Damrose, Luisa Lina Villa, Leonardo da Silva IntroductionHPV infection is the most prevalent sexually transmitted disease worldwide. One of the barriers to the implementation of prevention programs against the disease is the limit...περισσότερα »

Recurrent Aphthous Ulcers

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
[image: http:--www.clinicalevidence.bmj.com-imag] [image: http:--www.ncbi.nlm.nih.gov-corehtml-pmc] *Aphthous ulcers (recurrent).* BMJ Clin Evid. Authors: Porter SR, Scully Cbe C Abstract INTRODUCTION: Most people with recurrent aphthous ulcers develop a few ulcers less than 1 cm in diameter, that heal after 5-14 days without scarring. The causes are unknown, but risks of recurrence may decrease if the person gives up smoking. Local physical trauma may trigger ulcers in susceptible people. In 10% of sufferers, lesions are more than 1 cm in diameter, and can cause scarring. ME... περισσότερα »

A 55-Year-Old Male with a Pituitary Tumor

Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 31 δευτερόλεπτα
from Anatomy Pathology via ola Kala on Inoreader http://ift.tt/1SErNRE via IFTTT

Feeding and reflux in children after mandibular distraction osteogenesis for micrognathia

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
: A systematic review via International Journal of Pediatric Otorhinolaryngology Publication date: June 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 85 Author(s): Omar Breik, Kandiah Umapathysivam, David Tivey, Peter Anderson Mandibular distraction osteogenesis (MDO) is becoming increasingly more commonly used as in neonates and infants with upper airway obstruction secondary to micrognathia. A significant number of these children are dependent on nasoenteric feeding or gastrostomies after birth for adequate nutrition and often suffer from gastro-esophage...περισσότερα »

Mouth breathing on exercise induced fall in lung function in children with allergic asthma and rhinitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
The effect of via International Journal of Pediatric Otorhinolaryngology Publication date: July 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 86 Author(s): Mirjana Turkalj, Jelena Živković, Marcel Lipej, Sandra Bulat Lokas, Damir Erceg, Srđan Ante Anzić, Robert Magdić, Davor Plavec ObjectivesExercise induced bronchospasm (EIB) represents a common feature of childhood asthma which is most commonly revealed during free running. On the other hand aerobic exercise shows significant beneficial effects in asthmatics especially on the reduction of the level of s...περισσότερα »

Public health approach to pediatric hearing impairment

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
Overview of a public health approach to pediatric hearing impairment in the Pacific Islands via International Journal of Pediatric Otorhinolaryngology Publication date: July 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 86 Author(s): Annette Kaspar, Joseph Kei, Carlie Driscoll, De Wet Swanepoel, Helen Goulios BackgroundChildhood hearing impairment is a significant cause of disability in developing countries. Otitis media and meningitis are leading infectious causes of preventable hearing loss in children. It is estimated that the Pacific Islands have amon... περισσότερα »

The paradigm model of distorted doctor-patient relationship

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
in Southern Iran: a grounded theory study: The doctor-patient relationship (DPR) is one of the most important subjects in medical sociology and health policy. Due to mutual understanding, undistorted DPRs not only result in satisfaction of both doctors and patients, but also help to reduce financial burdens for patients and the health care system. The purpose of this research was to identify a DPR based on the qualitative paradigm model which is called the grounded theory (GT) methodology. The data were collected from 3 focus groups, the participants of which consisted of 21 facul... περισσότερα »

What is the best treatment of incidental papillary thyroid microcarcinoma?

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
What is the best treatment of incidental papillary thyroid microcarcinoma?: [PDF] από researchgate.net Lymph node metastasis from 259 *papillary thyroid microcarcinomas*: frequency, pattern of occurrence and recurrence, and optimal strategy for neck dissection N Wada, QY Duh, K Sugino, H Iwasaki… - Annals of …, 2003 - journals.lww.com *...* The *management* of these clinically inapparent *thyroid* tumors ( *thyroid* incidentalomas) is controversial. *...* Two of the 24 also had upper mediastinum node dissection at initial *treatment*. *...* patients who underwent thyroidectomy for ...περισσότερα »

It is critical to screen patients with rheumatoid arthritis for hearing impairment

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
The objective of this review is to evaluate published clinical reports related to hearing impairment in patients with RA. from #Audiology via ola Kala on Inoreader http://ift.tt/26nIKH8 via IFTTT

Vesicular Stomatitis Virus Unassembled Nucleoprotein and its Phosphoprotein Chaperone.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
Ensemble Structure of the Highly Flexible Complex Formed between J Mol Biol. 2016 Apr 20; Authors: Yabukarksi F, Leyrat C, Martinez N, Communie G, Ivanov I, Ribeiro EA, Buisson M, Gerard FC, Bourhis JM, Jensen MR, Bernadó P, Blackledge M, Jamin M Abstract Nucleocapsid assembly is an essential process in the replication of the non-segmented, negative-sense RNA viruses (NNVs). Unassembled nucleoprotein (N(0)) is maintained in an RNA-free and monomeric form by its viral chaperone, the phosphoprotein (P), forming the N(0)-P complex. Our earlier work solved the structure of vesicular ...περισσότερα »

Manual laryngeal reposturing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα
as a primary approach for mutational falsetto: [image: cover.gif?v=1&s=70d968db1aa799c81f57954d] Objectives/Hypothesis Mutational falsetto is a functional voice disorder characterized by failure of the male high-pitched preadolescent voice to transition to the lower pitch of adolescence and adulthood. Few objective outcomes data exist regarding the effectiveness of voice therapy for this poorly understood disorder. This study examined the immediate effects of a single therapy session using manual laryngeal reposturing as a primary approach in the management of mutational falset... περισσότερα »

Endoscopic multiband mucosectomy for early esophageal squamous cell neoplasia

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 36 δευτερόλεπτα
Long-term outcomes of Gastrointest Endosc. 2016 Apr 20; Authors: Wang Z, Lu H, Wu L, Yuan B, Liu J, Shi H, Wang F Abstract BACKGROUND AND AIMS: Endoscopic multiband mucosectomy (EMBM) has been used to treat early Barrett's esophagus and esophagogastric junction(EGJ) neoplasia, yet it is seldom reported for the treatment of early esophageal squamous cell neoplasia. Here we retrospectively evaluated the feasibility, safety, and efficacy of EMBM for early esophageal squamous cell neoplasia. METHODS: A total of 125 patients were included. Lesions were delineated using electrocoagulat... περισσότερα »

Anatomy by whole body dissection: a new Masters of Surgery course

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 37 δευτερόλεπτα
Background In 2012, a new anatomy by whole body dissection-Masters of Surgery (WBD-MS) course was introduced as a subject within the MS degree at Sydney Medical School. The purpose of this study, based on two iterations of the course, implemented in 2012 and 2013, was to investigate the participants' knowledge acquisition of clinical topographical anatomy and perceptions of the course. Methods During 2012 and 2013, a total of 26 postgraduate surgical trainees enrolled in the WBD-MS course. Each cohort participated in a 34-day dissection course over 12 weeks. Within each course, ...περισσότερα »

Pain in pancreatic cancer: review of medical and surgical remedies

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 37 δευτερόλεπτα
Pancreatic cancer is a malignant tumour with very poor prognosis and a chance for 5-year survival is approximately 6%. One of the main symptoms of this neoplasm is pain, mostly of neuropathic origin, which significantly decreases the quality of life and impairs the functional activity of patients. The most common treatment of pain in pancreatic cancer is conservative therapy which is based on analgesic ladder rules established by the World Health Organization. Unfortunately, it is not always effective and it has many side effects that also can diminish patients' quality of life. ... περισσότερα »

Impact of parenchymal preserving surgery on survival and recurrence after liver resection for colorectal liver metastasis

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 37 δευτερόλεπτα
Background This study aimed to investigate the impact of non-anatomical liver resection (NAR) versus anatomical resection (AR) in patients with colorectal liver metastasis (CRLM), with regard to perioperative and long-term outcomes. Methods Analysis of prospectively collected data for patients with CRLM who underwent either AR or NAR between January 1993 and August 2011 was performed. The impact of AR and NAR on morbidity, mortality, margin positivity, redo liver resections, overall survival (OS) and disease free survival (DFS) was analysed. Results A total of 1574 resections ... περισσότερα »

Recent Advances in Antibiotic-Based, Antibiotic-Free and Ethnomedical Treatments against Methicillin-Resistant Staphylococcus aureus Wound Infections

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 38 δευτερόλεπτα
Staphylococcus aureus is the most common pathogen of wound infections. Thus far, methicillin-resistant S. aureus (MRSA) has become the major causative agent in wound infections, especially for nosocomial infections. MRSA infections are seldom eradicated by routine antimicrobial therapies. More concerning, some strains have become resistant to the newest antibiotics of last resort. Furthermore, horizontal transfer… Continue reading IJMS, Vol. 17, Pages 617: New Is Old, and Old Is New: Recent Advances in Antibiotic-Based, Antibiotic-Free and Ethnomedical Treatments against Methicillin... περισσότερα »

TNFSF15 Inhibits Blood Retinal Barrier Breakdown Induced by Diabetes

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 38 δευτερόλεπτα
Tumor necrosis factor superfamily 15 (TNFSF15) is an endogenous neovascularization inhibitor and an important negative regulator of vascular homeostasis. This study aimed to explore the potential role of TNFSF15 in diabetic retinopathy. Vitreous TNFSF15 and VEGF levels in proliferative diabetic retinopathy (PDR) patients were detected by ELISA. Retinal expression of TNFSF15 and the content of… Continue reading IJMS, Vol. 17, Pages 615: TNFSF15 Inhibits Blood Retinal Barrier Breakdown Induced by Diabetes

[Laryngeal effect of experimental postnatal hypothyroidism: do thyroid hormone receptors change?]

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 43 δευτερόλεπτα
*[Laryngeal effect of experimental postnatal hypothyroidism: do thyroid hormone receptors change?]* Kulak Burun Bogaz Ihtis Derg. 2016 May-Jun;26(3):164-8 Authors: Eryılmaz A, Günel C, Eliyatkın N, Cesur G, Türe M, Başal Y Abstract OBJECTIVES: In this study, we aimed to investigate the laryngeal histopathological alterations and thyroid hormone receptors in rats with experimentally-induced postnatal hypothyroidism. MATERIALS AND METHODS: In this prospective, randomized study, pregnant Wistar albino rats were followed and newborn 20 Wistar albino rat pups were included in the study... περισσότερα »

Similarities and differences among eosinophilic esophagitis, proton-pump inhibitor-responsive esophageal eosinophilia, and reflux esophagitis: comparisons of clinical, endoscopic, and histopathological findings in Japanese patients.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα
*Similarities and differences among eosinophilic esophagitis, proton-pump inhibitor-responsive esophageal eosinophilia, and reflux esophagitis: comparisons of clinical, endoscopic, and histopathological findings in Japanese patients.* J Gastroenterol. 2016 Apr 23; Authors: Jiao D, Ishimura N, Maruyama R, Ishikawa N, Nagase M, Oshima N, Aimi M, Okimoto E, Mikami H, Izumi D, Okada M, Ishihara S, Kinoshita Y Abstract BACKGROUND: Esophageal eosinophilia is classified as either eosinophilic esophagitis (EoE) or proton-pump inhibitor-responsive esophageal eosinophilia (PPI-REE), depend...περισσότερα »

Early reintervention after anterior cervical spine surgery: Epidemiology and risk factors: A case-control study.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα
*Early reintervention after anterior cervical spine surgery: Epidemiology and risk factors: A case-control study.* Orthop Traumatol Surg Res. 2016 Apr 20; Authors: Boudissa M, Lebecque J, Boissière L, Gille O, Pointillart V, Obeid I, Vital JM Abstract INTRODUCTION: Anterior cervical spine surgery is a frequent and effective procedure; complications are rare, but potentially fatal. The objective of the present study was to assess epidemiology and risk factors for early reintervention in anterior cervical spine surgery. METHODS: A retrospective case-control study recruited 2319 pati... περισσότερα »

A clinically unsuspected nasopharyngeal sarcoidosis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα
*A clinically unsuspected nasopharyngeal sarcoidosis.* Kulak Burun Bogaz Ihtis Derg. 2016 May-Jun;26(3):169-71 Authors: Tuğrul S, Göktaş SS, Özücer B, Sönmez FC, Özturan O Abstract Sarcoidosis is a multi-system disease which rarely involves the upper respiratory tract, leading to hoarseness, dysphagia, laryngeal paralysis, and upper airway obstruction. The Waldeyer's ring involvement in sarcoidosis is also very rare. In this article, we report a 32-year-old male case in whom a nasopharyngeal mass was detected based on the Waldeyer's ring involvement due to sarcoidosis. PMID: 2710...περισσότερα »

Similarities and differences among eosinophilic esophagitis, proton-pump inhibitor-responsive esophageal eosinophilia, and reflux esophagitis: comparisons of clinical, endoscopic, and histopathological findings in Japanese patients.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα
*Similarities and differences among eosinophilic esophagitis, proton-pump inhibitor-responsive esophageal eosinophilia, and reflux esophagitis: comparisons of clinical, endoscopic, and histopathological findings in Japanese patients.* J Gastroenterol. 2016 Apr 23; Authors: Jiao D, Ishimura N, Maruyama R, Ishikawa N, Nagase M, Oshima N, Aimi M, Okimoto E, Mikami H, Izumi D, Okada M, Ishihara S, Kinoshita Y Abstract BACKGROUND: Esophageal eosinophilia is classified as either eosinophilic esophagitis (EoE) or proton-pump inhibitor-responsive esophageal eosinophilia (PPI-REE), depend...περισσότερα »

Early reintervention after anterior cervical spine surgery: Epidemiology and risk factors: A case-control study.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα
*Early reintervention after anterior cervical spine surgery: Epidemiology and risk factors: A case-control study.* Orthop Traumatol Surg Res. 2016 Apr 20; Authors: Boudissa M, Lebecque J, Boissière L, Gille O, Pointillart V, Obeid I, Vital JM Abstract INTRODUCTION: Anterior cervical spine surgery is a frequent and effective procedure; complications are rare, but potentially fatal. The objective of the present study was to assess epidemiology and risk factors for early reintervention in anterior cervical spine surgery. METHODS: A retrospective case-control study recruited 2319 pati... περισσότερα »

A clinically unsuspected nasopharyngeal sarcoidosis.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα
*A clinically unsuspected nasopharyngeal sarcoidosis.* Kulak Burun Bogaz Ihtis Derg. 2016 May-Jun;26(3):169-71 Authors: Tuğrul S, Göktaş SS, Özücer B, Sönmez FC, Özturan O Abstract Sarcoidosis is a multi-system disease which rarely involves the upper respiratory tract, leading to hoarseness, dysphagia, laryngeal paralysis, and upper airway obstruction. The Waldeyer's ring involvement in sarcoidosis is also very rare. In this article, we report a 32-year-old male case in whom a nasopharyngeal mass was detected based on the Waldeyer's ring involvement due to sarcoidosis. PMID: 2710...περισσότερα »

PulmCrit- Epinephrine challenge in sepsis: An empiric approach to catecholamines

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 46 δευτερόλεπτα
[image: epibanner2.gif?resize=750%2C267] A 55-year-old woman was admitted with toxic shock syndrome. Her norepinephrine requirement was labile, fluctuating between 15 mcg/min and 30 mcg/min. Bedside echocardiogram showed a dilated inferior vena cava without respiratory variability, and a normal ejection fraction. On examination her extremities were cool and her urine output was marginal. EMCrit by Josh Farkas. from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Vx82iz via IFTTT

Evaluation of radiocesium concentrations in new leaves of wild plants two years after the Fukushima Dai-ichi Nuclear Power Plant accident

Alexandros G. SfakianakisστοΑπεικονιστικήΠριν από 48 δευτερόλεπτα
[image: S0265931X.gif] Publication date: August 2016 *Source:*Journal of Environmental Radioactivity, Volume 160 Author(s): Yuki Sugiura, Michihiro Shibata, Yoshimune Ogata, Hajime Ozawa, Tsutomu Kanasashi, Chisato Takenaka Radiocesium (137Cs) transfer to plants immediately after the Fukushima Dai-ichi Nuclear Power Plant accident was investigated by collecting newly emerged leaf and soil samples between May 2011 and November 2012 from 20 sites in the Fukushima prefecture. Radiocesium concentrations in leaf and soil samples were measured to calculate concentration ratios (CR). Woody ... περισσότερα »

Rock music and hearing loss – to quote Who singer Roger Daltrey: «We’re all going deaf. We’re all wearing hearing aids»

From the interview: How’s your hearing? My hearing’s dreadful. We’re all going deaf. We’re all wearing hearing aids. No it’s true. I suggest to everybody over the age of 50 that have been going to loud concerts for years and years and years, go and have your hearing tested. You’d be surprised what you’re missing. […]

Cuticle and subsurface ornamentation of intact plant leaf epidermis under confocal and superresolution microscopy

ABSTRACT Plant cuticle micromorphology is an invaluable tool in modern ecology and paleoecology. It has expanded our knowledge of systematic relationships among diverse plant groups and can be used to identify fossil plants. Furthermore, fossil plant leaf micromorphology is used for reconstructing past environments, most notably for estimating atmospheric CO2 concentration. Here we outline a […]

IJMS, Vol. 17, Pages 619: Glycated Albumin versus Glycated Hemoglobin as a Glycemic Indicator in Diabetic Patients on Peritoneal Dialysis

Compared with glycated hemoglobin (HbA1c), glycated albumin (GA) is superior in estimating glycemic control in diabetic patients on hemodialysis (HD). However, the better index for assessment of glycemic control in diabetic patients on peritoneal dialysis (PD) and the impact of protein loss on GA are unknown. Twenty diabetic patients on HD were matched by age, […]

IJMS, Vol. 17, Pages 615: TNFSF15 Inhibits Blood Retinal Barrier Breakdown Induced by Diabetes

Tumor necrosis factor superfamily 15 (TNFSF15) is an endogenous neovascularization inhibitor and an important negative regulator of vascular homeostasis. This study aimed to explore the potential role of TNFSF15 in diabetic retinopathy. Vitreous TNFSF15 and VEGF levels in proliferative diabetic retinopathy (PDR) patients were detected by ELISA. Retinal expression of TNFSF15 and the content of […]

Erratum to: Significance of endothelial progenitor cells (EPC) for tumorigenesis of head and neck squamous cell carcinoma (HNSCC): possible marker of tumor progression and neovascularization?

Erratum to: Significance of endothelial progenitor cells (EPC) for tumorigenesis of head and neck squamous cell carcinoma (HNSCC): possible marker of tumor progression and neovascularization? Clin Oral Investig. 2016 Apr 23; Authors: Ziebart T, Blatt S, Günther C, Voelxen N, Pabst A, Sagheb K, Kühl S, Lambrecht T PMID: 27108343 [PubMed – as supplied by […]

Direct perturbation of neural integrator by bilateral galvanic vestibular stimulation.


Direct perturbation of neural integrator by bilateral galvanic vestibular stimulation. Med Biol Eng Comput. 2016 Apr 23; Authors: Hong K, Shim HM, Goh M, Jang SY, Lee S, Kim KS Abstract Caloric vestibular stimulation (CVS) and galvanic vestibular stimulation (GVS) act primarily on the peripheral vestibular system. Although the electrical current applied during GVS is […]

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