Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Κυριακή 3 Απριλίου 2016

OtoRhinoLaryngology & Medicine,New Articles,April 3rd,2016


[Diagnosis of auditory processing disorders in children].

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*[Diagnosis of auditory processing disorders in children].* HNO. 2016 Apr 1; Authors: Ptok M, Miller S, Kühn D Abstract Despite normal hearing thresholds in pure tone audiometry, 0.5-1 % of children have difficulty understanding what they hear. An auditory processing disorder (APD) can be assumed, which should be clarified and treated. Based on a selective literature search in the PubMed and Scopus databases using the term "auditory processing disorder", several consensus papers are discussed. Numerous studies on APD have revealed partially contradicting results, thus fueling cri... περισσότερα »

[Medical examination: preparation for ENT specialisation : Part 24].

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*[Medical examination: preparation for ENT specialisation : Part 24].* HNO. 2016 Apr 1; Authors: Marek A PMID: 27038032 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1pWgRow via IFTTT

Fighting Global Disparities in Cancer Care: A Surgical Oncology View.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Fighting Global Disparities in Cancer Care: A Surgical Oncology View.* Ann Surg Oncol. 2016 Apr 1; Authors: Hoekstra HJ, Wobbes T, Heineman E, Haryono S, Aryandono T, Balch CM Abstract Cancer is the second leading cause of death globally after cardiovascular disease. Long-term cancer survival has improved in the Western world due to early detection and the use of effective combined treatment modalities, as well as the development of effective immunotherapy and drug-targeted therapy. Surgery is still the mainstay for most solid tumors; however, low- and middle-income countries are... περισσότερα »

Effects of paclitaxel on permanent head and neck squamous cell carcinoma cell lines and identification of anti-apoptotic caspase 9b.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Effects of paclitaxel on permanent head and neck squamous cell carcinoma cell lines and identification of anti-apoptotic caspase 9b.* J Cancer Res Clin Oncol. 2016 Apr 1; Authors: Maushagen R, Reers S, Pfannerstill AC, Hahlbrock A, Stauber R, Rahmanzadeh R, Rades D, Pries R, Wollenberg B Abstract PURPOSE: Paclitaxel is an effective chemotherapeutic agent against various human tumors inducing apoptosis via binding to β-tubulin of microtubules and arresting cells mainly in the G2/M phase of the cell cycle. However, the underlying specific molecular mechanisms of paclitaxel on head ... περισσότερα »

[Multicenter trial for sudden hearing loss therapy - planning and concept].

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*[Multicenter trial for sudden hearing loss therapy - planning and concept].* HNO. 2016 Apr 1; Authors: Plontke SK, Girndt M, Meisner C, Probst R, Oerlecke I, Richter M, Steighardt J, Dreier G, Weber A, Baumann I, Plößl S, Löhler J, Laszig R, Werner JA, Rahne T Abstract Systemic steroids are widely used worldwide as a standard of care for primary therapy of idiopathic sudden sensorineural hearing loss (ISSHL). The German ISSHL guideline recommends high-dose steroids for primary therapy of ISSHL, without evidence from randomized controlled trials (RCTs). The rationale for the tre... περισσότερα »

The clinical diagnostic value of target biopsy using narrow-band imaging endoscopy and accurate laryngeal carcinoma pathologic specimen acquisition.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*The clinical diagnostic value of target biopsy using narrow-band imaging endoscopy and accurate laryngeal carcinoma pathologic specimen acquisition.* Clin Otolaryngol. 2016 Apr 2; Authors: Yang Y, Liu J, Song F, Zhang S Abstract OBJECTIVE: To estimate the clinical significance of target biopsy for clinical diagnosis and determine accurate laryngeal lesion pathologic specimen acquisition via narrow-band imaging (NBI) endoscopy. METHODS: A total of 138 samples from patients with laryngeal lesions (carcinoma, 118; hyperplasia, 3; mild dysplasia, 2; moderate dysplasia, 5; severe dysp... περισσότερα »

Fifty Sixth Annual Meeting of the Irish Otorhinolaryngology/Head and Neck Society.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Fifty Sixth Annual Meeting of the Irish Otorhinolaryngology/Head and Neck Society.* Ir J Med Sci. 2016 Apr 1; Authors: PMID: 27037565 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1X8zbWc via IFTTT

Don't neglect the sinus!

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Don't neglect the sinus!* Clin Med (Lond). 2016 Apr;16(2):204 Authors: Bakshi SS PMID: 27037397 [PubMed - in process] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1qoCqOQ via IFTTT

HER2 and HER3 in HPV+ and HPV- HNSCC-Letter.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*HER2 and HER3 in HPV+ and HPV- HNSCC-Letter.* Clin Cancer Res. 2016 Apr 1;22(7):1825 Authors: Machiels JP, Galot R, Schmitz S PMID: 27037254 [PubMed - in process] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1X8z9O9 via IFTTT

Coupling of an active middle-ear implant to the long process of the incus using an elastic clip attachment.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Coupling of an active middle-ear implant to the long process of the incus using an elastic clip attachment.* Hear Res. 2016 Mar 29; Authors: Schraven SP, Mlynski R, Dalhoff E, Heyd A, Wildenstein D, Rak K, Radeloff A, Hagen R, Gummer AW Abstract The active middle-ear implant Vibrant Soundbridge(©) (VSB) is used to treat mild-to-severe sensorineural hearing losses. The standard surgical approach for incus vibroplasty is a mastoidectomy and a posterior tympanotomy, crimping the Floating Mass Transducer (FMT) to the long process of the incus (LPI) (standard crimped application). Ho... περισσότερα »

Morphology of the distal thoracic duct and the right lymphatic duct in different head and neck pathologies: an imaging based study.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Morphology of the distal thoracic duct and the right lymphatic duct in different head and neck pathologies: an imaging based study.* Head Face Med. 2016;12(1):15 Authors: Kammerer FJ, Schlude B, Kuefner MA, Schlechtweg P, Hammon M, Uder M, Schwab SA Abstract BACKGROUND: The purpose of this study was to assess the influence of head and neck pathologies on the detection rate, configuration and diameter of the thoracic duct (TD) and right lymphatic duct (RLD) in computed tomography (CT) of the head and neck. METHODS: One hundred ninety-seven patients were divided into the subgroups ... περισσότερα »

Quality of neck dissection operative reports.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Quality of neck dissection operative reports.* Am J Otolaryngol. 2016 Feb 15; Authors: Nocon CC, Cohen MA, Langerman AJ Abstract PURPOSE: The operative report is the official documentation of an operation and a key form of surgical communication. The objective of this study is to assess completeness of operative reports for neck dissections. METHODS: This is a retrospective review of narrative operative reports for neck dissections for head and neck squamous cell carcinoma. Forty-nine operative reports were provided by ten surgeons from seven academic institutions. Operative repo... περισσότερα »

Minicircle DNA-mediated endothelial nitric oxide synthase gene transfer enhances angiogenic responses of bone marrow-derived mesenchymal stem cells.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Minicircle DNA-mediated endothelial nitric oxide synthase gene transfer enhances angiogenic responses of bone marrow-derived mesenchymal stem cells.* Stem Cell Res Ther. 2016;7(1):48 Authors: Bandara N, Gurusinghe S, Chen H, Chen S, Wang LX, Lim SY, Strappe P Abstract BACKGROUND: Non-viral-based gene modification of adult stem cells with endothelial nitric oxide synthase (eNOS) may enhance production of nitric oxide and promote angiogenesis. Nitric oxide (NO) derived from endothelial cells is a pleiotropic diffusible gas with positive effects on maintaining vascular tone and pro... περισσότερα »

Detailed evaluation of an automated approach to interactive optimization for volumetric modulated arc therapy plans.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Detailed evaluation of an automated approach to interactive optimization for volumetric modulated arc therapy plans.* Med Phys. 2016 Apr;43(4):1818 Authors: Tol JP, Dahele M, Delaney AR, Doornaert P, Slotman BJ, Verbakel WF Abstract PURPOSE: Interactive optimization during treatment planning requires intermittent adjustment of organ-at-risk (OAR) objectives relative to the dose-volume histogram line. This is a labor-intensive process and the resulting plans are prone to variations in quality. The authors' in-house developed approach to automated interactive optimization (AIO) au... περισσότερα »

Musician advantage for speech-on-speech perception.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Musician advantage for speech-on-speech perception.* J Acoust Soc Am. 2016 Mar;139(3):EL51 Authors: Başkent D, Gaudrain E Abstract Evidence for transfer of musical training to better perception of speech in noise has been mixed. Unlike speech-in-noise, speech-on-speech perception utilizes many of the skills that musical training improves, such as better pitch perception and stream segregation, as well as use of higher-level auditory cognitive functions, such as attention. Indeed, despite the few non-musicians who performed as well as musicians, on a group level, there was a stro... περισσότερα »

Modeling the voice source in terms of spectral slopes.

Alexandros G. SfakianakisστοHead and NeckΠριν από 51 δευτερόλεπτα
*Modeling the voice source in terms of spectral slopes.* J Acoust Soc Am. 2016 Mar;139(3):1404 Authors: Garellek M, Samlan R, Gerratt BR, Kreiman J Abstract A psychoacoustic model of the voice source spectrum is proposed. The model is characterized by four spectral slope parameters: the difference in amplitude between the first two harmonics (H1-H2), the second and fourth harmonics (H2-H4), the fourth harmonic and the harmonic nearest 2 kHz in frequency (H4-2 kHz), and the harmonic nearest 2 kHz and that nearest 5 kHz (2 kHz-5 kHz). As a step toward model validation, experiments w... περισσότερα »

Microalbuminuria in Obese Young and Middle Aged Population: A Potential Marker of Cardiovascular Risk

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 λεπτό
Abstract Microalbuminuria is an established cardiovascular risk indicator in diabetes, hypertension and the general population. There is lack of information on MAU in healthy obese Indian adults and an ongoing debate whether obese adults deserve targeted identification and clinical intervention for MAU and prediabetes. We aimed to screen the healthy obese, young (group I) and middle aged (group II) adults for prevalence of MAU and prediabetes and study its association with Framingham risk score. The study included 50 healthy obese young (20–30 years) and middle aged adults (31–50 ... περισσότερα »

Ultrasound-Guided Transcutaneous Needle Biopsy of the Base of the Tongue and Floor of the Mouth From a Submental Approach.

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 λεπτό
*Ultrasound-Guided Transcutaneous Needle Biopsy of the Base of the Tongue and Floor of the Mouth From a Submental Approach.* J Ultrasound Med. 2016 Apr 1; Authors: Wagner JM, Conrad RD, Cannon TY, Alleman AM Abstract Limited data exist regarding the feasibility of ultrasound-guided transcutaneous biopsy of the base of the tongue and floor of the mouth. This retrospective study reviewed 8 cases with lesions in the base of the tongue or floor of the mouth that were biopsied by fine-needle aspiration. Core biopsy was also needed in 1 case. All biopsies were technically successful, a... περισσότερα »

Quality of neck dissection operative reports.

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 λεπτό
*Quality of neck dissection operative reports.* Am J Otolaryngol. 2016 Feb 15; Authors: Nocon CC, Cohen MA, Langerman AJ Abstract PURPOSE: The operative report is the official documentation of an operation and a key form of surgical communication. The objective of this study is to assess completeness of operative reports for neck dissections. METHODS: This is a retrospective review of narrative operative reports for neck dissections for head and neck squamous cell carcinoma. Forty-nine operative reports were provided by ten surgeons from seven academic institutions. Operative repo... περισσότερα »

Effects of paclitaxel on permanent head and neck squamous cell carcinoma cell lines and identification of anti-apoptotic caspase 9b.

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 λεπτό
*Effects of paclitaxel on permanent head and neck squamous cell carcinoma cell lines and identification of anti-apoptotic caspase 9b.* J Cancer Res Clin Oncol. 2016 Apr 1; Authors: Maushagen R, Reers S, Pfannerstill AC, Hahlbrock A, Stauber R, Rahmanzadeh R, Rades D, Pries R, Wollenberg B Abstract PURPOSE: Paclitaxel is an effective chemotherapeutic agent against various human tumors inducing apoptosis via binding to β-tubulin of microtubules and arresting cells mainly in the G2/M phase of the cell cycle. However, the underlying specific molecular mechanisms of paclitaxel on head ... περισσότερα »

Pearls and Pitfalls in Diagnosing IgE-Mediated Food Allergy

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 2 δευτερόλεπτα
Abstract The term "food allergy" is used by many patients and clinicians to describe a range of symptoms that occur after ingestion of specific foods. However, not all symptoms occurring after food exposure are due to an allergic, or immunologic, response. It is important to properly evaluate and diagnose immunoglobulin E (IgE)-mediated food allergy as this results in reproducible, immediate onset, allergic reactions that can progress toward life-threatening anaphylaxis. Proper diagnosis requires understanding of the common foods that cause these reactions in addition to key histor... περισσότερα »

Epigenetic Dysfunction in Turner Syndrome Immune Cells

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 2 δευτερόλεπτα
Abstract Turner syndrome (TS) is a chromosomal condition associated with partial or complete absence of the X chromosome that involves characteristic findings in multiple organ systems. In addition to well-known clinical characteristics such as short stature and gonadal failure, TS is also associated with T cell immune alterations and chronic otitis media, suggestive of a possible immune deficiency. Recently, ubiquitously transcribed tetratricopeptide repeat on the X chromosome (UTX), a histone H3 lysine 27 (H3K27) demethylase, has been identified as a downregulated gene in TS imm... περισσότερα »

The Bromhead Care Home Service: the impact of a service for care home residents with dementia on hospital admission and dying in preferred place of care.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 δευτερόλεπτα
*The Bromhead Care Home Service: the impact of a service for care home residents with dementia on hospital admission and dying in preferred place of care.* Clin Med (Lond). 2016 Apr;16(2):114-8 Authors: Garden G, Green S, Pieniak S, Gladman J Abstract People with dementia have worse outcomes associated with hospital admission, are more likely to have interventions and are less likely to be offered palliative care than people without dementia. Advance care planning for care home residents has been shown to reduce hospital admissions without increasing mortality. Studies have shown... περισσότερα »

Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 δευτερόλεπτα
*Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report.* J Med Case Rep. 2016;10(1):74 Authors: Abe T, Kato M, Itagaki M, Hamatani S, Kawahara Y, Ito S, Aizawa Y, Matsuda K, Sumiyama K Abstract BACKGROUND: Esophageal verrucous carcinoma is a rare variant of esophageal squamous cell carcinoma. In most cases, verrucous carcinoma presents as an exophytic, slow-growing mass with an extensive superficial growth pattern. Symptoms often include an insidious onset of dysphagia resulting in weight loss. In a patient presenting with super early-stage ver... περισσότερα »

Ultrasound-Guided Transcutaneous Needle Biopsy of the Base of the Tongue and Floor of the Mouth From a Submental Approach.

Alexandros G. SfakianakisστοHead and NeckΠριν από 6 δευτερόλεπτα
*Ultrasound-Guided Transcutaneous Needle Biopsy of the Base of the Tongue and Floor of the Mouth From a Submental Approach.* J Ultrasound Med. 2016 Apr 1; Authors: Wagner JM, Conrad RD, Cannon TY, Alleman AM Abstract Limited data exist regarding the feasibility of ultrasound-guided transcutaneous biopsy of the base of the tongue and floor of the mouth. This retrospective study reviewed 8 cases with lesions in the base of the tongue or floor of the mouth that were biopsied by fine-needle aspiration. Core biopsy was also needed in 1 case. All biopsies were technically successful, a... περισσότερα »

Proteomic profiling identifies PTK2/FAK as a driver of radioresistance in HPV negative head and neck cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 6 δευτερόλεπτα
*Proteomic profiling identifies PTK2/FAK as a driver of radioresistance in HPV negative head and neck cancer.* Clin Cancer Res. 2016 Apr 1; Authors: Skinner HD, Giri U, Yang L, Woo SH, Story MD, Pickering CR, Byers LA, Williams MD, El-Naggar A, Wang J, Diao L, Shen L, Fan YH, Molkentine DP, Beadle BM, Meyn RE, Myers JN, Heymach JV Abstract PURPOSE: Head and neck squamous cell carcinoma (HNSCC) is commonly treated with radiotherapy, and local failure after treatment remains the major cause of disease-related mortality. To date human papillomavirus (HPV) is the only known clinicall... περισσότερα »

Probing the structure and dynamics of caveolin-1 in a caveolae-mimicking asymmetric lipid bilayer model

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 6 δευτερόλεπτα
Abstract Caveolin-1 is the principle membrane protein of caveolae and plays an important role in various cellular processes. The protein contains two helices (H1 and H2) connected by a three-residue break. Although caveolin-1 is assumed to adopt a U-shaped conformation in the transmembrane domain, with both the N-terminus and C-terminus exposed to the cytoplasm, the structure and dynamics of caveolin-1 in membranes are still unclear. Here, we performed six molecular dynamics simulations to characterize the structure and dynamics of caveolin-1 (residues D82–S136; Cav182–136) in a c... περισσότερα »

The Bromhead Care Home Service: the impact of a service for care home residents with dementia on hospital admission and dying in preferred place of care.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
*The Bromhead Care Home Service: the impact of a service for care home residents with dementia on hospital admission and dying in preferred place of care.* Clin Med (Lond). 2016 Apr;16(2):114-8 Authors: Garden G, Green S, Pieniak S, Gladman J Abstract People with dementia have worse outcomes associated with hospital admission, are more likely to have interventions and are less likely to be offered palliative care than people without dementia. Advance care planning for care home residents has been shown to reduce hospital admissions without increasing mortality. Studies have shown... περισσότερα »

Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
*Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report.* J Med Case Rep. 2016;10(1):74 Authors: Abe T, Kato M, Itagaki M, Hamatani S, Kawahara Y, Ito S, Aizawa Y, Matsuda K, Sumiyama K Abstract BACKGROUND: Esophageal verrucous carcinoma is a rare variant of esophageal squamous cell carcinoma. In most cases, verrucous carcinoma presents as an exophytic, slow-growing mass with an extensive superficial growth pattern. Symptoms often include an insidious onset of dysphagia resulting in weight loss. In a patient presenting with super early-stage ver... περισσότερα »

The Bromhead Care Home Service: the impact of a service for care home residents with dementia on hospital admission and dying in preferred place of care.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
*The Bromhead Care Home Service: the impact of a service for care home residents with dementia on hospital admission and dying in preferred place of care.* Clin Med (Lond). 2016 Apr;16(2):114-8 Authors: Garden G, Green S, Pieniak S, Gladman J Abstract People with dementia have worse outcomes associated with hospital admission, are more likely to have interventions and are less likely to be offered palliative care than people without dementia. Advance care planning for care home residents has been shown to reduce hospital admissions without increasing mortality. Studies have shown... περισσότερα »

Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
*Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report.* J Med Case Rep. 2016;10(1):74 Authors: Abe T, Kato M, Itagaki M, Hamatani S, Kawahara Y, Ito S, Aizawa Y, Matsuda K, Sumiyama K Abstract BACKGROUND: Esophageal verrucous carcinoma is a rare variant of esophageal squamous cell carcinoma. In most cases, verrucous carcinoma presents as an exophytic, slow-growing mass with an extensive superficial growth pattern. Symptoms often include an insidious onset of dysphagia resulting in weight loss. In a patient presenting with super early-stage ver... περισσότερα »

Inherent envelope fluctuations in forward maskers: Effects of masker-probe delay for listeners with normal and impaired hearing.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Inherent envelope fluctuations in forward maskers: Effects of masker-probe delay for listeners with normal and impaired hearing.* J Acoust Soc Am. 2016 Mar;139(3):1195 Authors: Svec A, Dubno JR, Nelson PB Abstract Forward-masked thresholds increase as the magnitude of inherent masker envelope fluctuations increase for both normal-hearing (NH) and hearing-impaired (HI) adults for a short masker-probe delay (25 ms). The slope of the recovery from forward masking is shallower for HI than for NH listeners due to reduced cochlear nonlinearities. However, effects of hearing loss on ad... περισσότερα »

Ultrasound-Guided Transcutaneous Needle Biopsy of the Base of the Tongue and Floor of the Mouth From a Submental Approach.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Ultrasound-Guided Transcutaneous Needle Biopsy of the Base of the Tongue and Floor of the Mouth From a Submental Approach.* J Ultrasound Med. 2016 Apr 1; Authors: Wagner JM, Conrad RD, Cannon TY, Alleman AM Abstract Limited data exist regarding the feasibility of ultrasound-guided transcutaneous biopsy of the base of the tongue and floor of the mouth. This retrospective study reviewed 8 cases with lesions in the base of the tongue or floor of the mouth that were biopsied by fine-needle aspiration. Core biopsy was also needed in 1 case. All biopsies were technically successful, a... περισσότερα »

Proteomic profiling identifies PTK2/FAK as a driver of radioresistance in HPV negative head and neck cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Proteomic profiling identifies PTK2/FAK as a driver of radioresistance in HPV negative head and neck cancer.* Clin Cancer Res. 2016 Apr 1; Authors: Skinner HD, Giri U, Yang L, Woo SH, Story MD, Pickering CR, Byers LA, Williams MD, El-Naggar A, Wang J, Diao L, Shen L, Fan YH, Molkentine DP, Beadle BM, Meyn RE, Myers JN, Heymach JV Abstract PURPOSE: Head and neck squamous cell carcinoma (HNSCC) is commonly treated with radiotherapy, and local failure after treatment remains the major cause of disease-related mortality. To date human papillomavirus (HPV) is the only known clinicall... περισσότερα »

Analysis of segmental mobility following a novel posterior apical short-segment correction for adolescent idiopathic scoliosis

AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 8 δευτερόλεπτα
BACKGROUND CONTEXT: The consequence of a spinal fusion is an abnormal load on adjacent levels with increased risk of future adjacent segment degeneration. from Sports Medicine via xlomafota13 on Inoreader http://ift.tt/1Vm9tyB via IFTTT

Peanut Allergy: New Developments and Clinical Implications

Peanut Allergy: New Developments and Clinical Implications: Abstract Food allergies have increased in prevalence over the past 20 years, now becoming an important public health concern. Although there are no therapies currently available for routine clinical care, recent reports have indicated that immunotherapies targeting the mucosal immune system may be effective. Oral immunotherapy is conducted […]

3-dimensional morphology of the upper lip configuration at the completion of facial expressions

Preliminary analysis of the three-dimensional morphology of the upper lip configuration at the completion of facial expressions in healthy Japanese young adults and patients with cleft lip via Oral and Maxillofacial Surgery Publication date: Available online 31 March 2016 Source:Journal of Oral and Maxillofacial Surgery Author(s): Kouzou Matsumoto, Etsuro Nozoe, Takako Okawachi, Kiyohide Ishihata, Kazuhide […]

Seasonality of cleft births

– The Brazil experience via ScienceDirect Publication: Journal of Oral Biology and Craniofacial Research Publication date: Available online 1 April 2016 Source:Journal of Oral Biology and Craniofacial Research Author(s): Sibele Nascimento de Aquino, Renato Assis Machado, Lívia Máris R. Paranaíba, Daniella Reis B. Martelli, Daniela Araújo Veloso Popoff, Mário Sérgio O. Swerts, Hercílio Martelli-Júnior AimsEvaluate […]

BMP and NF-κB pathways regulates osteoblastic bone formation

Fine-tuning between via ScienceDirect Publication: Journal of Oral Biosciences Publication date: Available online 1 April 2016 Source:Journal of Oral Biosciences Author(s): Shizu Hirata-Tsuchiya, Hidefumi Fukushima, Shoichiro Kokabu, Chiaki Kitamura, Eijiro Jimi BackgroundBone morphogenetic proteins (BMPs) enhance bone formation and osteoblast differentiation in vivo and in vitro via a Smad signaling pathway. Recent findings have revealed […]

Cytogenetic and immunohistochemical biomarker profiling of therapy-relevant factors in salivary gland carcinomas

Cytogenetic and immunohistochemical biomarker profiling of therapy-relevant factors in salivary gland carcinomas: Objectives There is currently no established algorithm for the molecular profiling of therapy-relevant defects in salivary gland carcinomas (SGC). HER2 overexpression in a subfraction of SGC and low frequencies of EGFR mutations are known. Here, we established receptor and cell signalling profiles of […]

Tissue Expansion-Assisted Techniques of Cleft Palate Repair.

A Review of : Background: The purpose of this report was to examine current knowledge of use of tissue expansion techniques to assist cleft palate repair and to review and contrast various techniques reported. Methods: Two separate literature searches were conducted in the Cochrane Library, CINAHL, Medline and Embase databases, from database inception until December […]

Selective Photon Shield in Dual-Energy Computed Tomography Angiography for Diagnosis of Intracranial Aneurysms.

Application Value of : Purpose: The aim of the study was to investigate the image quality of dual-energy computed tomography angiography (DECTA) using the selective photon shield (SPS) technique to diagnose intracranial aneurysms. Materials and Methods: Eighty patients with a suspected intracranial aneurysm were randomly assigned to undergo DECTA with SPS (ie, SPS-DECTA) or DECTA […]

Platelet-Rich Fibrin Plays a Role in Healing Acute-Traumatic Ear Drum Perforations.

In Response to: from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1orRgTm via IFTTT

Iliac Crest Donor Site for Children With Cleft Lip and Palate Undergoing Alveolar Bone Grafting: A Long-term Assessment.

Iliac Crest Donor Site for Children With Cleft Lip and Palate Undergoing Alveolar Bone Grafting: A Long-term Assessment.: The authors aimed to accurately assess the donor site morbidity from iliac crest bone grafts for secondary bone grafting in patients with cleft lip and palate alveolar defects. Fifty patients between 3 months and 10 years following […]

Low-Grade Myofibroblastic Sarcoma of the Larynx.

Low-Grade Myofibroblastic Sarcoma of the Larynx.: Low-grade myofibroblastic sarcoma is a malignant tumor of myofibroblasts, which has only recently become more clearly defined. It represents a rare entity that progresses in a slow-growing infiltrative pattern inside deep soft tissues. Due to its rarity and the plasticity of the myofibroblast, it can cause significant diagnostic difficulties. […]

Laryngeal symptoms induced in patients with allergic rhinitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Characteristics of laryngeal symptoms induced in patients with allergic rhinitis in an environmental challenge chamber via ScienceDirect Publication: Annals of Allergy, Asthma & Immunology Publication date: Available online 2 April 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Takeshi Suzuki, Yoshitaka Okamoto, Syuji Yonekura, Yusuke Okuma, Toshioki Sakurai, Daiju Sakurai BackgroundPeople with allergic rhinitis often have laryngeal symptoms (LSs) in addition to nasal symptoms during the pollen-scattering season.ObjectiveTo clarify the characteristics of the LSs induced... περισσότερα »

Food allergy prevalence and management

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
at an overnight summer camp via ScienceDirect Publication: Annals of Allergy, Asthma & Immunology Publication date: Available online 2 April 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Margaret Redmond, Erin Kempe, Kasey Strothman, Kara Wada, Rebecca Scherzer, David R. Stukus BackgroundIn recent years, increased awareness of food allergy management has focused on the school setting. A lack of awareness and relevant literature prompted evaluation of the camp experience.ObjectivesTo characterize the prevalence of food allergies among children attending an overnight s... περισσότερα »

Epigenetic Dysfunction in Turner Syndrome Immune Cells

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Epigenetic Dysfunction in Turner Syndrome Immune Cells: AbstractTurner syndrome (TS) is a chromosomal condition associated with partial or complete absence of the X chromosome that involves characteristic findings in multiple organ systems. In addition to well-known clinical characteristics such as short stature and gonadal failure, TS is also associated with T cell immune alterations and chronic otitis media, suggestive of a possible immune deficiency. Recently, ubiquitously transcribed tetratricopeptide repeat on the X chromosome (UTX), a histone H3 lysine 27 (H3K27) demethylase,... περισσότερα »

Pearls and Pitfalls in Diagnosing IgE-Mediated Food Allergy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Pearls and Pitfalls in Diagnosing IgE-Mediated Food Allergy: AbstractThe term “food allergy” is used by many patients and clinicians to describe a range of symptoms that occur after ingestion of specific foods. However, not all symptoms occurring after food exposure are due to an allergic, or immunologic, response. It is important to properly evaluate and diagnose immunoglobulin E (IgE)-mediated food allergy as this results in reproducible, immediate onset, allergic reactions that can progress toward life-threatening anaphylaxis. Proper diagnosis requires understanding of the commo... περισσότερα »

Peanut Allergy: New Developments and Clinical Implications

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Peanut Allergy: New Developments and Clinical Implications: AbstractFood allergies have increased in prevalence over the past 20 years, now becoming an important public health concern. Although there are no therapies currently available for routine clinical care, recent reports have indicated that immunotherapies targeting the mucosal immune system may be effective. Oral immunotherapy is conducted by administering small, increasing amounts of food allergen; it has shown promise for desensitizing individuals with peanut, egg, or milk allergies. Sublingual immunotherapy also desensit... περισσότερα »

Peanut Allergy: New Developments and Clinical Implications

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Peanut Allergy: New Developments and Clinical Implications: AbstractFood allergies have increased in prevalence over the past 20 years, now becoming an important public health concern. Although there are no therapies currently available for routine clinical care, recent reports have indicated that immunotherapies targeting the mucosal immune system may be effective. Oral immunotherapy is conducted by administering small, increasing amounts of food allergen; it has shown promise for desensitizing individuals with peanut, egg, or milk allergies. Sublingual immunotherapy also desensit... περισσότερα »

3-dimensional morphology of the upper lip configuration at the completion of facial expressions

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Preliminary analysis of the three-dimensional morphology of the upper lip configuration at the completion of facial expressions in healthy Japanese young adults and patients with cleft lip via Oral and Maxillofacial Surgery Publication date: Available online 31 March 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Kouzou Matsumoto, Etsuro Nozoe, Takako Okawachi, Kiyohide Ishihata, Kazuhide Nishinara, Norifumi Nakamura PurposeTo develop criteria for analysis of the upper lip configuration of patients with cleft lip while they produce various facial expressions, by com... περισσότερα »

Seasonality of cleft births

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
– The Brazil experience via ScienceDirect Publication: Journal of Oral Biology and Craniofacial Research Publication date: Available online 1 April 2016 *Source:*Journal of Oral Biology and Craniofacial Research Author(s): Sibele Nascimento de Aquino, Renato Assis Machado, Lívia Máris R. Paranaíba, Daniella Reis B. Martelli, Daniela Araújo Veloso Popoff, Mário Sérgio O. Swerts, Hercílio Martelli-Júnior AimsEvaluate the seasonal influence in nonsyndromic cleft lip and/or palate (NSCL/P) in Brazilian patients.MethodsA case-control study, with 361 unrelated patients with NSCL/P and 481 he... περισσότερα »

BMP and NF-κB pathways regulates osteoblastic bone formation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Fine-tuning between via ScienceDirect Publication: Journal of Oral Biosciences Publication date: Available online 1 April 2016 *Source:*Journal of Oral Biosciences Author(s): Shizu Hirata-Tsuchiya, Hidefumi Fukushima, Shoichiro Kokabu, Chiaki Kitamura, Eijiro Jimi BackgroundBone morphogenetic proteins (BMPs) enhance bone formation and osteoblast differentiation in vivo and in vitro via a Smad signaling pathway. Recent findings have revealed that inhibition of nuclear factor-κB (NF-κB) enhances BMP-induced osteoblast differentiation both in vitro and in vivo, suggesting that NF-κB nega... περισσότερα »

Cytogenetic and immunohistochemical biomarker profiling of therapy-relevant factors in salivary gland carcinomas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
Cytogenetic and immunohistochemical biomarker profiling of therapy-relevant factors in salivary gland carcinomas: [image: cover.gif?v=1&s=a0ff55faa388bf623a351a74] Objectives There is currently no established algorithm for the molecular profiling of therapy-relevant defects in salivary gland carcinomas (SGC). HER2 overexpression in a subfraction of SGC and low frequencies of EGFR mutations are known. Here, we established receptor and cell signalling profiles of 17 therapy-relevant factors and propose a molecular diagnostic algorithm for SGC. Materials and Methods Formalin-fixed ... περισσότερα »

Tissue Expansion-Assisted Techniques of Cleft Palate Repair.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
A Review of : Background: The purpose of this report was to examine current knowledge of use of tissue expansion techniques to assist cleft palate repair and to review and contrast various techniques reported. Methods: Two separate literature searches were conducted in the Cochrane Library, CINAHL, Medline and Embase databases, from database inception until December 2014 for use of mucoperiosteal expansion (MPE) and distraction osteogenesis (DO) in cleft palate repair. Results: Six articles, reporting a total of 51 patients of palatal MPE, were identified for discussion and analys... περισσότερα »

Selective Photon Shield in Dual-Energy Computed Tomography Angiography for Diagnosis of Intracranial Aneurysms.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
Application Value of : Purpose: The aim of the study was to investigate the image quality of dual-energy computed tomography angiography (DECTA) using the selective photon shield (SPS) technique to diagnose intracranial aneurysms. Materials and Methods: Eighty patients with a suspected intracranial aneurysm were randomly assigned to undergo DECTA with SPS (ie, SPS-DECTA) or DECTA without SPS (ie, DECTA). The objective image quality of these 2 groups was compared with digital subtraction angiography and surgical results as the reference. The location, number, and morphology of the ... περισσότερα »

Platelet-Rich Fibrin Plays a Role in Healing Acute-Traumatic Ear Drum Perforations.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
In Response to:

Iliac Crest Donor Site for Children With Cleft Lip and Palate Undergoing Alveolar Bone Grafting: A Long-term Assessment.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Iliac Crest Donor Site for Children With Cleft Lip and Palate Undergoing Alveolar Bone Grafting: A Long-term Assessment.: The authors aimed to accurately assess the donor site morbidity from iliac crest bone grafts for secondary bone grafting in patients with cleft lip and palate alveolar defects. Fifty patients between 3 months and 10 years following alveolar bone grafting for cleft lip and palate were entered into the study. Two-thirds of patients had no significant concerns about the donor site. The remaining third had some concerns about the appearance of their hips and less tha... περισσότερα »

Low-Grade Myofibroblastic Sarcoma of the Larynx.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Low-Grade Myofibroblastic Sarcoma of the Larynx.: Low-grade myofibroblastic sarcoma is a malignant tumor of myofibroblasts, which has only recently become more clearly defined. It represents a rare entity that progresses in a slow-growing infiltrative pattern inside deep soft tissues. Due to its rarity and the plasticity of the myofibroblast, it can cause significant diagnostic difficulties. Differencing this neoplasm from other spindle cell tumors requires the use of ancillary techniques such as immunohistochemistry and/or electron microscopy. The authors report an unusual case of ... περισσότερα »

Guided Surgery in Esthetic Region.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Guided Surgery in Esthetic Region.: The placement of dental implants and subsequent placement of immediate temporary dentures after extractions has become a treatment modality accepted by the scientific community. In addition to the functional factor, the surgical procedure in a single stage in the anterior region of the maxilla offers an esthetic appearance, and relieves the psychological concerns of patients. To guarantee the success and longevity of treatments performed, the fabrication of surgical guides is a helpful method in these situations. Guided surgery has gained attentio... περισσότερα »

Extended Posterior Auricular Artery Flap for Temporo-Parietal Scalp Defect in Previously Irradiated Scalp.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Extended Posterior Auricular Artery Flap for Temporo-Parietal Scalp Defect in Previously Irradiated Scalp.: Background: Temperoparietal scalp defects are fairly common resulting from varied array of etiology. Various reconstructive options exisit, but the aim was to achieve a reliable and simple solution keeping in mind the principle of replacing "like with like." Methods: The authors present a 83-year-old lady who had a fall at her home and was lying unconscious for quite some time on her right side of her temple, leading to full thickness necrosis of overlying scalp. She had recei... περισσότερα »

Dysphagia in tongue cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
Dysphagia in tongue cancer patients before and after surgery via Oral and Maxillofacial Surgery Publication date: Available online 2 April 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Zhuo-shan Huang, Wei-liang Chen, Zhi-quan Huang, Zhao-hui Yang PurposeTo define factors influencing postoperative aspiration in tongue cancer patients and to analyze the characteristics of dysphagia before and after surgery.MethodsA total of 112 tongue cancer patients participated in the present work. Videofluoroscopic swallowing studies (VFSSs) were performed on all patients before a... περισσότερα »

Autologous and Alloplastic Cranioplasty in the Pediatric Population.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
An Outcomes Comparison Between Autologous and Alloplastic Cranioplasty in the Pediatric Population.: Background: The use of alloplastic material in cranial reconstruction has been well described in the adult population, especially when a paucity of autologous tissue exists. In children it is unknown how long-term growth, however, may be affected by the implantation of nonexpansible alloplastic material. Therefore, the authors sought to compare the outcomes of pediatric patients undergoing alloplastic versus autologous cranial reconstruction. Methods: To assess the safety and long-te... περισσότερα »

Platelet-rich fibrin and piezosurgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
Evaluation of the effects of platelet-rich fibrin and piezosurgery on outcomes after removal of ımpacted mandibular third molars: We compared postoperative outcomes after the removal of 80 impacted mandibular third molars in 59 patients. In the control group, osteotomies were done with traditional burs (n=20). The second group had traditional osteotomies and platelet-rich fibrin (PRF) placed into the socket of the extracted tooth (n=20). The third group had piezosurgery (n=20), and the fourth had piezosurgery and PRF placed in the extraction socket (n=20). Baseline variables were as... περισσότερα »

Reconstruction of the tongue and mouth floor with the myofascial vastus lateralis free flap after cancer ablation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Reconstruction of the tongue and mouth floor with the myofascial vastus lateralis free flap after cancer ablation: The current study was undertaken to evaluate a novel approach to tongue and mouth floor reconstruction using the myofascial vastus lateralis free flap (MVLF). The surgical techniques, benefits, complication rate, and the aesthetic and functional results are described. A series of six patients underwent functional tongue reconstruction between July 2013 and November 2014. The myofascial vastus lateralis flap was obtained as follows: the vastus lateralis muscle was expose... περισσότερα »

Cause-effect relationship between vocal fold physiology and voice production in a three-dimensional phonation model

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Cause-effect relationship between vocal fold physiology and voice production in a three-dimensional phonation model: The goal of this study is to better understand the cause-effect relation between vocal fold physiology and the resulting vibration pattern and voice acoustics. Using a three-dimensional continuum model of phonation, the effects of changes in vocal fold stiffness, medial surface thickness in the vertical direction, resting glottal opening, and subglottal pressure on vocal fold vibration and different acoustic measures are investigated. The results show that the medial... περισσότερα »

Early-onset epileptic encephalopathy with hearing loss in two siblings with TBC1D24 recessive mutations.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Authors: Stražišar BG, Neubauer D, Paro Panjan D, Writzl K Abstract BACKGROUND: Recent studies have shown that recessive mutations in the TBC1D24 gene cause a variety of epilepsy syndromes, DOORS syndrome and nonsyndromic deafness. METHODS/RESULTS: We report on two siblings with hypotonia, early-onset epileptic encephalopathy, and severe developmental delay. The patients presented with clonic and myoclonic jerks within 1 h after birth. The seizures were resistant to treatment. Audiologic examination showed bilateral sensorineural ... περισσότερα »

The 6-minute walk test

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
Effect of the 6-minute walk test on plantar loading and capability to produce ankle plantar flexion forces via Gait & Posture Publication date: Available online 1 April 2016 *Source:*Gait & Posture Author(s): Bruno Vie, Patricia Griffon, Bijoux Audrey, Cadiere Julie, Jean Paul Weber, Yves Jammes The six-minute walk test (6MWT) is used to evaluate the ambulatory capacity of patients suffering from respiratory disorders, obesity or neuromuscular diseases. Our primary aim was to evaluate the effects of the 6MWT on the postural sway and the ankle plantar flexion forces in healthy subjects.... περισσότερα »

Categorization of common sounds by cochlear implanted and normal hearing adults

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
Categorization of common sounds by cochlear implanted and normal hearing adults via Hearing Research Publication date: Available online 2 April 2016 *Source:*Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes (categorization) and low-level perceptual encoding of the acoustic signal, both of which are affected ... περισσότερα »

Multichannel Vestibular Implant Early Feasibility Study

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
Multichannel Vestibular Implant Early Feasibility Study: *Conditions*: Other Disorders of Vestibular Function, Bilateral; Bilateral Vestibular Deficiency (BVD); Gentamicin Ototoxicity; Labyrinth Diseases; Vestibular Diseases; Sensation Disorders *Intervention*: Device: Labyrinth Devices MVI™ Multichannel Vestibular Implant *Sponsors*: Johns Hopkins University; National Institute on Deafness and Other Communication Disorders (NIDCD); Labyrinth Devices, LLC Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, t... περισσότερα »

Lenvatinib for Anaplastic Thyroid Cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Phase II Study Assessing the Efficacy and Safety of Lenvatinib for Anaplastic Thyroid Cancer: *Condition*: Anaplastic Thyroid Cancer *Intervention*: Drug: Lenvatinib *Sponsor*: Translational Research Informatics Center, Kobe, Hyogo, Japan The purpose of this phase Ⅱ study is to assess the efficacy and safety of lenvatinib for anaplastic thyroid cancer patients who are diagnosed as resectable. The total duration of the study will be 30 months. All patients will start administrarion of lenvatinib within 1 week of enrollment and receive the study drug 24mg orally once daily at ... περισσότερα »

Bilateral neck fistulas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
*Bilateral neck fistulas* *via European Annals of Otorhinolaryngology, Head and Neck Diseases* *Publication date: Available online 31 March 2016* Figures and tables 1. *[image: Two pinpoint openings were present since birth in a 24-year-old male who gave ...]* 2. *[image: On fistulogram, two tracks (one on each side) were seen leading to the tonsillar ...]* 3. *[image: Fistulogram showing the contrast has opacified two tracks (one on each side) ...]* *Source:European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): R. Bhoil, K. Thakur, R. Bhoil*... περισσότερα »

Hyaluronic acid and upper airway inflammation in pediatric population

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα
: A systematic review via International Journal of Pediatric Otorhinolaryngology Publication date: June 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 85 Author(s): Casale Manuele, Vella Paola, Moffa Antonio, Oliveto Giuseppe, Sabatino Lorenzo, Grimaldi Valentina, Ferrara Pietro, Salvinelli Fabrizio BackgroundInflammatory disease of upper airway in pediatric population represents a social problem for both the pharmaco-economic impact and a burden for the family. To date, the use of topical therapies represents a significant therapeutic progress because they... περισσότερα »

Anemia increases cochlear dysfunction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα
Protein energy malnutrition associates with different types of hearing impairments in toddlers: Anemia increases cochlear dysfunction via International Journal of Pediatric Otorhinolaryngology Publication date: June 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 85 Author(s): Terez Boshra Kamel, Tharwat Ezzat Deraz, Rasha H. Elkabarity, Rasha K. Ahmed ObjectivesThis work aimed to highlight a challenging asymptomatic problem which is early detection of hearing impairment in toddlers with protein energy malnutrition (PEM) as a neuro-cognitive effect of PEM on... περισσότερα »

Facial Nerve and Parotid Gland…..Otolaryngologic Clinics of North America

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 36 δευτερόλεπτα
Parotitis and Sialendoscopy of the Parotid Gland Nonneoplastic disorders of the salivary glands involve inflammatory processes. These disorders have been managed conservatively with antibiotics, warm compresses, massage, sialogogues, and adequate hydration. Up to 40% of patients may have an inadequate response or persistent symptoms. When conservative techniques fail, the next step is operative intervention. Sialendoscopy… Continue reading Facial Nerve and Parotid Gland…..Otolaryngologic Clinics of North America

Quinine, Malaria, and the Cinchona Bureau: Marketing Practices and Knowledge Circulation in a Dutch Transoceanic Cinchona-Quinine Enterprise (1920s-30s)

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 36 δευτερόλεπτα
Quinine, Malaria, and the Cinchona Bureau: Marketing Practices and Knowledge Circulation in a Dutch Transoceanic Cinchona-Quinine Enterprise (1920s-30s): In this study, we will show how a Dutch pharmaceutical consortium of cinchona producers and quinine manufacturers was able to capitalize on one of the first international public health campaigns to fight malaria, thereby promoting the sale… Continue reading Quinine, Malaria, and the Cinchona Bureau: Marketing Practices and Knowledge Circulation in a Dutch Transoceanic Cinchona-Quinine Enterprise (1920s-30s)

Constitutional Therapy and Clinical Racial Hygiene in Weimar and Nazi Germany

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 36 δευτερόλεπτα
Constitutional Therapy and Clinical Racial Hygiene in Weimar and Nazi Germany: The paper examines the history of constitutional therapy in Weimar and Nazi Germany. Focusing on Walther Jaensch’s «Institute for Constitutional Research» at the Charité in Berlin, it shows how an entrepreneurial scientist successfully negotiated the changing social and political landscape of two very different… Continue reading Constitutional Therapy and Clinical Racial Hygiene in Weimar and Nazi Germany

«The Glamour of Arabic Numbers»: Pliny Earle’s Challenge to Nineteenth-Century Psychiatry

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 36 δευτερόλεπτα
«The Glamour of Arabic Numbers»: Pliny Earle’s Challenge to Nineteenth-Century Psychiatry: A well-established interpretation associates the nineteenth-century psychiatrist Pliny Earle’s deflation of high cure rates for insanity with the onset of a persistent malaise in patient treatment and public health policy during the Gilded Age. This essay comes not to praise Earle but to correct… Continue reading «The Glamour of Arabic Numbers»: Pliny Earle’s Challenge to Nineteenth-Century Psychiatry

Biological activities of skin and parotoid gland secretions of bufonid toads (Bufo bufo, Bufo verrucosissimus and Bufotes variabilis) from Turkey

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 36 δευτερόλεπτα
Publication date: May 2016 Source:Biomedicine & Pharmacotherapy, Volume 80 Author(s): Ayse Nalbantsoy, Mert Karış, Husniye Tansel Yalcin, Bayram Göçmen Toad glandular secretions and skin extractions contain numerous natural agents which may provide unique resources for novel drug development. Especially the skin-parotoid gland secretions of toads from genus Bufo contain as many as 86 different types… Continue reading Biological activities of skin and parotoid gland secretions of bufonid toads (Bufo bufo, Bufo verrucosissimus and Bufotes variabilis) from Turkey

Race, Poverty, and the Negotiation of Women’s Health

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 36 δευτερόλεπτα
in New York City, 1915-1930: Tanya Hart. Health in the City: Race, Poverty, and the Negotiation of Women’s Health in New York City, 1915–1930. New York, New York University Press, 2015. 327 pp., illus., $55.00. James Colgrove –Author Affiliations Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, New York 10032… Continue reading Race, Poverty, and the Negotiation of Women’s Health

Music, Mechanism, and the «Sonic Turn» in Physical Diagnosis

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 36 δευτερόλεπτα
Music, Mechanism, and the «Sonic Turn» in Physical Diagnosis: The sonic diagnostic techniques of percussion and mediate auscultation advocated by Leopold von Auenbrugger and R. T. H. Laennec developed within larger musical contexts of practice, notation, and epistemology. Earlier, Francois-Nicolas Marquet proposed a musical notation of pulse that connected felt pulsation with heard music. Though… Continue reading Music, Mechanism, and the «Sonic Turn» in Physical Diagnosis

Aging Bones

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 36 δευτερόλεπτα
Chronic Disease in the Twentieth Century: A History * Aging Bones: A Short History of Osteoporosis: George Weisz. Chronic Disease in the Twentieth Century: A History. Baltimore, Johns Hopkins University Press, 2014. vii, 307 pp., $29.95. Gerald N. Grob. Aging Bones: A Short History of Osteoporosis. Baltimore, Johns Hopkins University Press, 2014. xx, 284 pp.,… Continue reading Aging Bones

THYROSIM App for Education and Research Predicts Potential Health Risks of Over-the-Counter Thyroid Supplements

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 36 δευτερόλεπτα
THYROSIM App for Education and Research Predicts Potential Health Risks of Over-the-Counter Thyroid Supplements: Thyroid Apr 2016, Vol. 26, No. 4: 489-498. Author information Simon X. Han,1 Marisa Eisenberg,2 P. Reed Larsen,3 and Joseph DiStefano III1 1Biocybernetics Laboratory, Departments of Computer Science and Medicine, UCLA, Los Angeles, California. 2Departments of Epidemiology and Mathematics, School of… Continue reading THYROSIM App for Education and Research Predicts Potential Health Risks of Over-the-Counter Thyroid Supplements

Minimal Extrathyroidal Extension in Papillary Thyroid Carcinoma

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 36 δευτερόλεπτα
Inter-Observer Variation in the Pathologic Identification of Minimal Extrathyroidal Extension in Papillary Thyroid Carcinoma: Thyroid Apr 2016, Vol. 26, No. 4: 512-517. Author information Jiunn-Diann Lin,1,2,3 Shuai-Shuai Fu,4 Jui-Yu Chen,5 Chen-Hsen Lee,5 Wing-Keung Chau,6 Chao-Wen Cheng,1Yuan-Hung Wang,1,7 Yuh-Feng Lin,1,8 Wen-Fang Fang,9 and Kam-Tsun Tang10 1Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University,… Continue reading Minimal Extrathyroidal Extension in Papillary Thyroid Carcinoma

Evaluation of the protective effects of hesperetin against cisplatin-induced ototoxicity

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 37 δευτερόλεπτα
in a rat animal model via International Journal of Pediatric Otorhinolaryngology Publication date: June 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 85 Author(s): Medine Kara, Hakan Türkön, Turan Karaca, Oğuz Güçlü, Sema Uysal, Mehmet Türkyılmaz, Selim Demirtaş, Fevzi Sefa Dereköy ObjectivesWe aimed to investigate the effects of hesperetin as a flavanon both histopathologically and immunohistochemically on cochlear apoptosis in a rat model of cisplatin-induced ototoxicity (CIO). The evaluation of the effects of hesperetin on cisplatin-induced hearing los... περισσότερα »

Knowledge and attitude (KA) survey regarding infant hearing loss

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 37 δευτερόλεπτα
in Karnataka, India via International Journal of Pediatric Otorhinolaryngology Publication date: June 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 85 Author(s): Rohit Ravi, Krishna Yerraguntla, Dhanshree R. Gunjawate, Bellur Rajashekhar, Leslie E. Lewis, Vasudeva Guddattu IntroductionThe support provided and the decisions taken by mothers determine the success of Universal Newborn Hearing Screening (UNHS). Attempts at exploring the existing knowledge-attitude among mothers is crucial to create/modify the existing screening programs. The present study at... περισσότερα »

Facial Nerve and Parotid Gland.Otolaryngologic Clinics of North America

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 37 δευτερόλεπτα
Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland by Aaron G. Lewis, Tommy Tong, Ellie Maghami via Otolaryngologic Clinics of North America [image: gr1.sml] Malignant parotid tumors are heterogeneous and diverse. Accurate diagnosis requires a pathologist familiar with the various histologic subtypes, immunohistochemistry stains, and common translocations. Clinical course varies according to tumor subtype, ranging from indolent, slow-growing adenoid cystic carcinoma to rapidly progressive, possibly fatal, salivary ductal carcinoma. Histologic grade is... περισσότερα »

Facial Nerve and Parotid Gland.....Otolaryngologic Clinics of North America

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 37 δευτερόλεπτα
Parotitis and Sialendoscopy of the Parotid Gland Nonneoplastic disorders of the salivary glands involve inflammatory processes. These disorders have been managed conservatively with antibiotics, warm compresses, massage, sialogogues, and adequate hydration. Up to 40% of patients may have an inadequate response or persistent symptoms. When conservative techniques fail, the next step is operative intervention. Sialendoscopy offers a minimally invasive option for the diagnosis and management of chronic inflammatory disorders of the salivary glands and offers the option of gland and fun... περισσότερα »

Race, Poverty, and the Negotiation of Women's Health

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 37 δευτερόλεπτα
in New York City, 1915-1930: [image: oxford_open_small.gif] Tanya Hart. *Health in the City: Race, Poverty, and the Negotiation of Women's Health in New York City, 1915–1930*. New York, New York University Press, 2015. 327 pp., illus., $55.00. 1. James Colgrove -Author Affiliations 1. Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, New York 10032 1. Key words - infant mortality - maternal mortality - charity - maternalist reform - public health New York City provides an ideal setting for historians ... περισσότερα »

Music, Mechanism, and the "Sonic Turn" in Physical Diagnosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 46 δευτερόλεπτα
Music, Mechanism, and the "Sonic Turn" in Physical Diagnosis: The sonic diagnostic techniques of percussion and mediate auscultation advocated by Leopold von Auenbrugger and R. T. H. Laennec developed within larger musical contexts of practice, notation, and epistemology. Earlier, Francois-Nicolas Marquet proposed a musical notation of pulse that connected felt pulsation with heard music. Though contemporary vitalists rejected Marquet's work, mechanists such as Albrecht von Haller included it into the larger discourse about the physiological manifestations of bodily fluids and fibe... περισσότερα »

Aging Bones

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 46 δευτερόλεπτα
Chronic Disease in the Twentieth Century: A History * Aging Bones: A Short History of Osteoporosis: [image: oxford_open_small.gif] George Weisz. *Chronic Disease in the Twentieth Century: A History*. Baltimore, Johns Hopkins University Press, 2014. vii, 307 pp., $29.95. Gerald N. Grob. *Aging Bones: A Short History of Osteoporosis*. Baltimore, Johns Hopkins University Press, 2014. xx, 284 pp., $24.95. 1. Cara Kiernan Fallon, M.P.H., Ph.D. Candidate -Author Affiliations 1. Department of the History of Science, Harvard University, Cambridge, Massachusetts 02138 1. ... περισσότερα »

THYROSIM App for Education and Research Predicts Potential Health Risks of Over-the-Counter Thyroid Supplements

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 46 δευτερόλεπτα
THYROSIM App for Education and Research Predicts Potential Health Risks of Over-the-Counter Thyroid Supplements: Thyroid Apr 2016, Vol. 26, No. 4: 489-498. Author information Simon X. Han,1 Marisa Eisenberg,2 P. Reed Larsen,3 and Joseph DiStefano III1 1Biocybernetics Laboratory, Departments of Computer Science and Medicine, UCLA, Los Angeles, California. 2Departments of Epidemiology and Mathematics, School of Public Health, University of Michigan, Ann Arbor, Michigan. 3Brigham and Women's Hospital/Harvard Medical School, Department of Medicine, Boston, Massachusetts. Address corres... περισσότερα »

Minimal Extrathyroidal Extension in Papillary Thyroid Carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 49 δευτερόλεπτα
Inter-Observer Variation in the Pathologic Identification of Minimal Extrathyroidal Extension in Papillary Thyroid Carcinoma: [image: access_free.gif] Thyroid Apr 2016, Vol. 26, No. 4: 512-517. Author information Jiunn-Diann Lin,1,2,3 Shuai-Shuai Fu,4 Jui-Yu Chen,5 Chen-Hsen Lee,5 Wing-Keung Chau,6 Chao-Wen Cheng,1Yuan-Hung Wang,1,7 Yuh-Feng Lin,1,8 Wen-Fang Fang,9 and Kam-Tsun Tang10 1Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. 2Division of Endocrinology and Metabolism, Department of Internal Medicine, Shuang Ho Hospi... περισσότερα »

Geographic Distribution and Evolution of Thyroid Cancer Epidemic

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 50 δευτερόλεπτα
in South Korea: [image: access_free.gif] Thyroid , Vol. 0, No. 0. Author information Juan P. Brito,1 Hyun Jung Kim,2 Seung Jin Han,3 Young Sung Lee,4 and Hyeong Sik Ahn2 1Division of Endocrinology, Diabetes, Metabolism, and Nutrition and Knowledge and Evaluation Research Unit in Endocrinology (KER_Endo), Mayo Clinic, Rochester, Minnesota. 2Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea. 3Department of Public Health, Graduate School, Korea University, Seoul, Korea. 4College of Medicine and MedRIC & PSM, Chungbuk National University, Cheon... περισσότερα »

Medical Futility

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 50 δευτερόλεπτα
Conceptualization of Idle (Laghw) and its Relation to Medical Futility: A major debate in medical ethics is the request for futile treatment. The topic of medical futility requires discrete assessment in Iran for at least two reasons. First, the common principles and foundations of medical ethics have taken shape in the context of Western culture and secularism. Accordingly, the implementation of the same guidelines and codes of medical ethics as Western societies in Muslim communities does not seem rational. Second, the challenges arising in health service settings are divergent a... περισσότερα »

Duloxetine Hydrochloride-Induced Oral Lichenoid Reaction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
[image: http:--misc.karger.com-LinkOutIcons-sk_n] Authors: Kadam NS, Patil RA, Gurav AN, Shete A, Jadhav PD, Naik Tari R, Metkari S, Agarwal D Abstract OBJECTIVE: To report the first case of duloxetine hydrochloride (DH)-induced oral lichenoid drug reaction (OLDR). CLINICAL PRESENTATION AND INTERVENTION: A 57-year-old male patient presented with painful ulcerative lesions on the bilateral buccal mucosa of 2-year duration. The patient was on multiple drug therapy for his systemic ailments. After thorough evaluation for possible medical ailments and with the physician's consent, wi... περισσότερα »

Prevention and treatment of mucositis in children with oral cancers

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα
Practical recommendations].: Cancer Radiother. 2016 Mar 28; Authors: El Bousaadani A, Eljahd L, Abada R, Rouadi S, Roubal M, Mahtar M Abstract Oral mucositis is an inflammation of the mucosa of the oral cavity of various etiologies. This is a common and debilitating complication in children treated with chemoradiotherapy for cancer. Its management remains a major concern both for the doctor than the patient. It affects the quality of life of patients and families. It may initiate the functional and vital prognosis because of the judgment of cancer treatment. Several treatment opti... περισσότερα »

Oncolytic Rhabdo-Virotherapy.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα
Murine Tumor Models ILAR J. 2016 Mar 31;57(1):73-85 Authors: Falls T, Roy DG, Bell JC, Bourgeois-Daigneault MC Abstract The preclinical optimization and validation of novel treatments for cancer therapy requires the use of laboratory animals. Although in vitro experiments using tumor cell lines and ex vivo treatment of patient tumor samples provide a remarkable first-line tool for the initial study of tumoricidal potential, tumor-bearing animals remain the primary option to study delivery, efficacy, and safety of therapies in the context of a complete tumor microenvironment and f... περισσότερα »

Treatment of oral mucositis due to chemotherapy.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα
Treatment of oral mucositis due to chemotherapy.: *Treatment of oral mucositis due to chemotherapy.* J Clin Exp Dent. 2016 Apr;8(2):e201-9 Authors: Chaveli-López B, Bagán-Sebastián JV Abstract INTRODUCTION: The management of oral mucositis is a challenge, due to its complex biological nature. Over the last 10 years, different strategies have been developed for the management of oral mucositis caused by chemotherapy in cancer patients. MATERIAL AND METHODS: An exhaustive search was made of the PubMed-Medline, Cochrane Library and Scopus databases, crossing the key words "oral muc... περισσότερα »

Target biopsy using narrow-band imaging endoscopy and accurate laryngeal carcinoma pathologic specimen acquisition

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα
The clinical diagnostic value of target biopsy using narrow-band imaging endoscopy and accurate laryngeal carcinoma pathologic specimen acquisition: Abstract Objective To estimate the clinical significance of target biopsy for clinical diagnosis and determine accurate laryngeal lesion pathologic specimen acquisition via narrow-band imaging (NBI) endoscopy. Methods A total of 138 samples from patients with laryngeal lesions (carcinoma, 118; hyperplasia, 3; mild dysplasia, 2; moderate dysplasia, 5; severe dysplasia, 5; vocal cord polyp, 1; and inflammatory lesion, 4) were collected fr... περισσότερα »

Severe late dysphagia and cause of death after concurrent chemoradiation for larynx cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα
in patients eligible for RTOG 91-11 via ScienceDirect Publication: Oral Oncology Publication date: June 2016 *Source:*Oral Oncology, Volume 57 Author(s): Matthew C. Ward, David J. Adelstein, Priyanka Bhateja, Tobenna I. Nwizu, Joseph Scharpf, Narcissa Houston, Eric D. Lamarre, Robert Lorenz, Brian B. Burkey, John F. Greskovich, Shlomo A. Koyfman PurposeThe long-term results of RTOG 91-11 suggested increased deaths not attributed to larynx cancer after concomitant chemoradiotherapy (CRT) despite no apparent increase in late effects. Because the timing of events was not reported by RTOG... περισσότερα »

Sinonasal inverted papilloma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
: From diagnosis to treatment via European Annals of Otorhinolaryngology, Head and Neck Diseases Publication date: Available online 1 April 2016 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): Q. Lisan, O. Laccourreye, P. Bonfils Inverted papilloma is a rare sinonasal tumor that mainly occurs in adults during the 5th decade. Three characteristics make this tumor very different from other sinonasal tumors: a relatively strong potential for local destruction, high rate of recurrence, and a risk of carcinomatous evolution. Etiology remains little understo... περισσότερα »

Propolis in allergic rhinitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
Effects of propolis in an experimental rat model of allergic rhinitis via American Journal of Otolaryngology Publication date: Available online 2 April 2016 *Source:*American Journal of Otolaryngology Author(s): Mehmet Yasar, Yasemin Savranlar, Hatice Karaman, Mustafa Sagit, Sibel Silici, Ibrahim Ozcan PurposeThe aim of this study was to determine the anti-allergic activity of propolis in an ovalbumin-induced rat model of allergic rhinitis.Materials and methodsThis prospective experimental study was conducted at Hakan Çetinsaya Clinical and Experimental Animal Research Center with 30 ra... περισσότερα »

HPV Vaccines for Treatment and Prevention of Recurrent Respiratory Papillomatosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα
HPV Vaccines for Treatment and Prevention of Recurrent Respiratory Papillomatosis: AbstractRecurrent respiratory papillomatosis (RRP) is a disease of viral etiology and is caused by the human papillomavirus (HPV). Although it is a benign disease process, there are very serious sequelae because of its involvement in the tracheobronchial tree. While there are multiple treatment modalities, ranging from surgery to antivirals and immunomodulating chemotherapeutics, recent advances have focused on the prevention of HPV transmission with vaccines. Over the last 10 years, HPV vaccination... περισσότερα »

Diagnostik auditiver Verarbeitungs- und Wahrnehmungsstörungen bei Kindern

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα
Diagnostik auditiver Verarbeitungs- und Wahrnehmungsstörungen bei Kindern: ZusammenfassungBei 0,5–1 % aller Kinder bestehen, trotz regelrechtem Tonschwellenaudiogramm, Schwierigkeiten mit dem Verstehen von Gehörtem. Hier kann eine auditive Verarbeitungs- und Wahrnehmungsstörung (AVWS) vermutet werden, die abgeklärt und therapiert werden sollte. Auf Basis einer selektiven Literaturrecherche mit dem Stichwort „auditory processing disorder*“ in den Literaturdatenbanken PubMed und Scopus werden verschiedene Konsensuspapiere erörtert. Zahlreiche Studien zur AVWS haben z. T. widersprüchl... περισσότερα »

Balloon Eustachian Tuboplasty and Tympanic Paracentesis on Intractable Chronic Otitis Media with Effusion

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 59 δευτερόλεπτα
Effect of the Combination of via American Journal of Otolaryngology Publication date: Available online 2 April 2016 *Source:*American Journal of Otolaryngology Author(s): Maojin Liang, Hao Xiong, Yuexin Cai, Yuebo Chen, Zhigang Zhang, Suijun Chen, Yaodong Xu, Yongkang Ou, Haidi Yang, Yiqing Zheng ObjectiveTo evaluate the effect of the combination of balloon Eustachian tuboplasty (BET) and tympanic paracentesis (TP) on intractable chronic otitis media with effusion (COME).MethodsNinety patients with intractable COME were included and randomly assigned to three groups: BET only (30 pati... περισσότερα »

Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease

New England Journal of Medicine, Ahead of Print. from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1MLhefV via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1pW8DNd via IFTTT

Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease

New England Journal of Medicine, Ahead of Print. from Uncategorized via xlomafota13 on Inoreader http://ift.tt/2219rw9 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1UATLke via IFTTT

More HOPE for Prevention with Statins

New England Journal of Medicine, Ahead of Print. from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1MLhg7w via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1pW8DN9 via IFTTT

Single subject analyses reveal consistent recruitment of frontal operculum in performance monitoring

Publication date: June 2016 Source:NeuroImage, Volume 133 Author(s): Céline Amiez, Magdalena G. Wutte, Isabelle Faillenot, Michael Petrides, Boris Burle, Emmanuel Procyk There are continuing uncertainties regarding whether performance monitoring recruits the anterior insula (aI) and/or the frontal operculum (fO). The proximity and morphological complexity of these two regions make proper identification and isolation of the […]

Alpha suppression and connectivity modulations in left temporal and parietal cortices index partial awareness of words

Publication date: June 2016 Source:NeuroImage, Volume 133 Author(s): Lorenzo Magazzini, Philipp Ruhnau, Nathan Weisz The partial awareness hypothesis is a theoretical proposal that recently provided a reconciling solution to graded and dichotomous accounts of consciousness. It suggests that we can become conscious of distinct properties of an object independently, ranging from low-level features to complex […]

Categorization of common sounds by cochlear implanted and normal hearing adults

Publication date: Available online 2 April 2016 Source:Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes […]

Categorization of common sounds by cochlear implanted and normal hearing adults

Publication date: Available online 2 April 2016 Source:Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes […]

Categorization of common sounds by cochlear implanted and normal hearing adults

Publication date: Available online 2 April 2016 Source:Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes […]

A Zebrafish Model of 5q-Syndrome Using CRISPR/Cas9 Targeting RPS14 Reveals a p53-Independent and p53-Dependent Mechanism of Erythroid Failure

Publication date: Available online 2 April 2016 Source:Journal of Genetics and Genomics Author(s): Jason Ear, Jessica Hsueh, Melinda Nguyen, QingHua Zhang, Victoria Sung, Rajesh Chopra, Kathleen M. Sakamoto, Shuo Lin 5q-syndrome is a distinct form of myelodysplastic syndrome (MDS) where a deletion on chromosome 5 is the underlying cause. MDS is characterized by bone marrow […]

Viola M. Frymann, D.O., F.A.A.O., Internationaly Recongnized And Pioneering Osteopathic Physican, Dies At 94 In San Diego, California By Dr. Hollis King, D.O., PhD

Publication date: Available online 2 April 2016 Source:Journal of Bodywork and Movement Therapies Author(s): Hollis H. King from Pharmacology via ola Kala on Inoreader http://ift.tt/1UMf4zI via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1X8hia1 via IFTTT

Medication at discharge in an orthopaedic surgical ward: quality of information transmission and implementation of a medication reconciliation form

Abstract Background Medication reconciliation (MedRec) at discharge is a cumbersome but necessary process to reduce the risk of medication errors at transitions of care. The main barriers to implementing such a process are the large number of professionals involved and a lack of collaboration among caregivers. Objective This study was designed to assess the need […]

The challenges of outcome research

Abstract Cognitive pharmacy trials seek to identify interventions that benefit patients. The potential benefits of an intervention are primarily evaluated by outcome measures. The question then is: What is the optimal outcome measure? Unfortunately, the question remains unsolved. Several factors must be taken into consideration when conducting outcome research—particularly within cognitive pharmacy trials. The interventions […]

Increased integrity of white matter pathways after dual n-back training

Publication date: June 2016 Source:NeuroImage, Volume 133 Author(s): Tiina Salminen, Johan Mårtensson, Torsten Schubert, Simone Kühn Dual n-back WM training has been shown to produce broad transfer effects to different untrained cognitive functions. The task is demanding to the cognitive system because it includes a bi-modal (auditory and visual) dual-task component. A previous WM training […]

Single subject analyses reveal consistent recruitment of frontal operculum in performance monitoring

Publication date: June 2016 Source:NeuroImage, Volume 133 Author(s): Céline Amiez, Magdalena G. Wutte, Isabelle Faillenot, Michael Petrides, Boris Burle, Emmanuel Procyk There are continuing uncertainties regarding whether performance monitoring recruits the anterior insula (aI) and/or the frontal operculum (fO). The proximity and morphological complexity of these two regions make proper identification and isolation of the […]

Alpha suppression and connectivity modulations in left temporal and parietal cortices index partial awareness of words

Publication date: June 2016 Source:NeuroImage, Volume 133 Author(s): Lorenzo Magazzini, Philipp Ruhnau, Nathan Weisz The partial awareness hypothesis is a theoretical proposal that recently provided a reconciling solution to graded and dichotomous accounts of consciousness. It suggests that we can become conscious of distinct properties of an object independently, ranging from low-level features to complex […]

Categorization of common sounds by cochlear implanted and normal hearing adults

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: alertIcon.gif] Publication date: Available online 2 April 2016 *Source:*Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes (categorization) and low-level perceptual encoding of the acoustic signal, both of which are affected by the use of a cochlear implant (CI) device. The goal of this study was twof... περισσότερα »

Categorization of common sounds by cochlear implanted and normal hearing adults

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: alertIcon.gif] Publication date: Available online 2 April 2016 *Source:*Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes (categorization) and low-level perceptual encoding of the acoustic signal, both of which are affected by the use of a cochlear implant (CI) device. The goal of this study was twof... περισσότερα »

Categorization of common sounds by cochlear implanted and normal hearing adults

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: alertIcon.gif] Publication date: Available online 2 April 2016 *Source:*Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes (categorization) and low-level perceptual encoding of the acoustic signal, both of which are affected by the use of a cochlear implant (CI) device. The goal of this study was twof... περισσότερα »

Increased integrity of white matter pathways after dual n-back training

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
[image: S10538119.gif] Publication date: June 2016 *Source:*NeuroImage, Volume 133 Author(s): Tiina Salminen, Johan Mårtensson, Torsten Schubert, Simone Kühn Dual n-back WM training has been shown to produce broad transfer effects to different untrained cognitive functions. The task is demanding to the cognitive system because it includes a bi-modal (auditory and visual) dual-task component. A previous WM training study showed increased white matter integrity in the parietal lobe as well as the anterior part of the corpus callosum after visual n-back training. We investigated dual n-... περισσότερα »

Single subject analyses reveal consistent recruitment of frontal operculum in performance monitoring

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
[image: S10538119.gif] Publication date: June 2016 *Source:*NeuroImage, Volume 133 Author(s): Céline Amiez, Magdalena G. Wutte, Isabelle Faillenot, Michael Petrides, Boris Burle, Emmanuel Procyk There are continuing uncertainties regarding whether performance monitoring recruits the anterior insula (aI) and/or the frontal operculum (fO). The proximity and morphological complexity of these two regions make proper identification and isolation of the loci of activation extremely difficult. The use of group averaging methods in human neuroimaging might contribute to this problem. The re... περισσότερα »

Alpha suppression and connectivity modulations in left temporal and parietal cortices index partial awareness of words

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
Publication date: June 2016 *Source:*NeuroImage, Volume 133 Author(s): Lorenzo Magazzini, Philipp Ruhnau, Nathan Weisz The partial awareness hypothesis is a theoretical proposal that recently provided a reconciling solution to graded and dichotomous accounts of consciousness. It suggests that we can become conscious of distinct properties of an object independently, ranging from low-level features to complex forms of representation. We investigated this hypothesis using classic visual word masking adapted to a near-threshold paradigm. The masking intensity was adjusted to the indivi... περισσότερα »

Effect of diphenyliodonium hexafluorophosphate on the physical and chemical properties of ethanolic solvated resins containing camphorquinone and 1-phenyl-1,2-propanedione sensitizers as initiators

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 3 April 2016 Source:Dental Materials Author(s): Diogo Dressano, Alan Rodrigo Palialol, Thaty A. Xavier, Roberto R. Braga, Joe D. Oxman, David C. Watts, Giselle Maria Marchi, Adriano Fonseca Lima ObjectivesTo evaluate the effects of the diphenyliodonium hexafluorophosphate (DPI) on the physical and mechanical properties of solvated dental adhesive resins containing camphorquinone… Continue reading Effect of diphenyliodonium hexafluorophosphate on the physical and chemical properties of ethanolic solvated resins containing camphorquinone and 1-phenyl... περισσότερα »

Categorization of common sounds by cochlear implanted and normal hearing adults

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 2 April 2016 Source:Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes… Continue reading Categorization of common sounds by cochlear implanted and normal hearing adults

Categorization of common sounds by cochlear implanted and normal hearing adults

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 2 April 2016 Source:Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes… Continue reading Categorization of common sounds by cochlear implanted and normal hearing adults

Effect of diphenyliodonium hexafluorophosphate on the physical and chemical properties of ethanolic solvated resins containing camphorquinone and 1-phenyl-1,2-propanedione sensitizers as initiators

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 3 April 2016 Source:Dental Materials Author(s): Diogo Dressano, Alan Rodrigo Palialol, Thaty A. Xavier, Roberto R. Braga, Joe D. Oxman, David C. Watts, Giselle Maria Marchi, Adriano Fonseca Lima ObjectivesTo evaluate the effects of the diphenyliodonium hexafluorophosphate (DPI) on the physical and mechanical properties of solvated dental adhesive resins containing camphorquinone… Continue reading Effect of diphenyliodonium hexafluorophosphate on the physical and chemical properties of ethanolic solvated resins containing camphorquinone and 1-phenyl... περισσότερα »

Viola M. Frymann, D.O., F.A.A.O., Internationaly Recongnized And Pioneering Osteopathic Physican, Dies At 94 In San Diego, California By Dr. Hollis King, D.O., PhD

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 2 April 2016 Source:Journal of Bodywork and Movement Therapies Author(s): Hollis H. King from Pharmacology via ola Kala on Inoreader http://ift.tt/1UMf4zI via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1X8hia1 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/230WgkU via IFTTT… Continue reading Viola M. Frymann, D.O., F.A.A.O., Internationaly Recongnized And Pioneering Osteopathic Physican, Dies At 94 In San Diego, California By... περισσότερα »

The Tract Terminations in the Temporal Lobe: Their location and associated functions

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 1 April 2016 Source:Cortex Author(s): Claude J. Bajada, Hamied A. Haroon, Hojjatollah Azadbakht, Geoff J.M. Parker, Matthew A. Lambon Ralph, Lauren L. Cloutman Temporal lobe networks are associated with multiple cognitive domains. Despite an upsurge of interest in connectional neuroanatomy, the terminations of the main fibre tracts in the human brain… Continue reading The Tract Terminations in the Temporal Lobe: Their location and associated functions

Powered by light: Phototrophy and photosynthesis in prokaryotes and its evolution

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 2 April 2016 Source:Microbiological Research Author(s): Beatrycze Nowicka, Jerzy Kruk Photosynthesis is a complex metabolic process enabling photosynthetic organisms to use solar energy for the reduction of carbon dioxide into biomass. This ancient pathway has revolutionized life on Earth. The most important event was the development of oxygenic photosynthesis. It had… Continue reading Powered by light: Phototrophy and photosynthesis in prokaryotes and its evolution

The role of biceps brachii and brachioradialis for the control of elbow flexion and extension movements

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 2 April 2016 Source:Journal of Electromyography and Kinesiology Author(s): Sylvie Charlotte Frieda Anneliese von Werder, Catherine Disselhorst-Klug How do synergistic muscles interact, when their contraction aims at stabilizing and fine- tuning a movement, which is induced by the antagonistic muscle? The aim of the study was to analyze the interaction of… Continue reading The role of biceps brachii and brachioradialis for the control of elbow flexion and extension movements

Full title (Editorial Board Members)

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: March 2016 Source:Advanced Powder Technology, Volume 27, Issue 2 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Y7QkQh via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1MLbNh2 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on… Continue reading Full title (Editorial Board Members)

A Zebrafish Model of 5q-Syndrome Using CRISPR/Cas9 Targeting RPS14 Reveals a p53-Independent and p53-Dependent Mechanism of Erythroid Failure

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: Available online 2 April 2016 Source:Journal of Genetics and Genomics Author(s): Jason Ear, Jessica Hsueh, Melinda Nguyen, QingHua Zhang, Victoria Sung, Rajesh Chopra, Kathleen M. Sakamoto, Shuo Lin 5q-syndrome is a distinct form of myelodysplastic syndrome (MDS) where a deletion on chromosome 5 is the underlying cause. MDS is characterized by bone marrow… Continue reading A Zebrafish Model of 5q-Syndrome Using CRISPR/Cas9 Targeting RPS14 Reveals a p53-Independent and p53-Dependent Mechanism of Erythroid Failure

A Zebrafish Model of 5q-Syndrome Using CRISPR/Cas9 Targeting RPS14 Reveals a p53-Independent and p53-Dependent Mechanism of Erythroid Failure

Publication date: Available online 2 April 2016 Source:Journal of Genetics and Genomics Author(s): Jason Ear, Jessica Hsueh, Melinda Nguyen, QingHua Zhang, Victoria Sung, Rajesh Chopra, Kathleen M. Sakamoto, Shuo Lin 5q-syndrome is a distinct form of myelodysplastic syndrome (MDS) where a deletion on chromosome 5 is the underlying cause. MDS is characterized by bone marrow […]

Effect of diphenyliodonium hexafluorophosphate on the physical and chemical properties of ethanolic solvated resins containing camphorquinone and 1-phenyl-1,2-propanedione sensitizers as initiators

Publication date: Available online 3 April 2016 Source:Dental Materials Author(s): Diogo Dressano, Alan Rodrigo Palialol, Thaty A. Xavier, Roberto R. Braga, Joe D. Oxman, David C. Watts, Giselle Maria Marchi, Adriano Fonseca Lima ObjectivesTo evaluate the effects of the diphenyliodonium hexafluorophosphate (DPI) on the physical and mechanical properties of solvated dental adhesive resins containing camphorquinone […]

The Tract Terminations in the Temporal Lobe: Their location and associated functions

Publication date: Available online 1 April 2016 Source:Cortex Author(s): Claude J. Bajada, Hamied A. Haroon, Hojjatollah Azadbakht, Geoff J.M. Parker, Matthew A. Lambon Ralph, Lauren L. Cloutman Temporal lobe networks are associated with multiple cognitive domains. Despite an upsurge of interest in connectional neuroanatomy, the terminations of the main fibre tracts in the human brain […]

Categorization of common sounds by cochlear implanted and normal hearing adults

Publication date: Available online 2 April 2016 Source:Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes […]

Effect of diphenyliodonium hexafluorophosphate on the physical and chemical properties of ethanolic solvated resins containing camphorquinone and 1-phenyl-1,2-propanedione sensitizers as initiators

Publication date: Available online 3 April 2016 Source:Dental Materials Author(s): Diogo Dressano, Alan Rodrigo Palialol, Thaty A. Xavier, Roberto R. Braga, Joe D. Oxman, David C. Watts, Giselle Maria Marchi, Adriano Fonseca Lima ObjectivesTo evaluate the effects of the diphenyliodonium hexafluorophosphate (DPI) on the physical and mechanical properties of solvated dental adhesive resins containing camphorquinone […]

Viola M. Frymann, D.O., F.A.A.O., Internationaly Recongnized And Pioneering Osteopathic Physican, Dies At 94 In San Diego, California By Dr. Hollis King, D.O., PhD

Publication date: Available online 2 April 2016 Source:Journal of Bodywork and Movement Therapies Author(s): Hollis H. King from Pharmacology via ola Kala on Inoreader http://ift.tt/1UMf4zI via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1X8hia1 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/230WgkU via IFTTT […]

Categorization of common sounds by cochlear implanted and normal hearing adults

Publication date: Available online 2 April 2016 Source:Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes […]

The Tract Terminations in the Temporal Lobe: Their location and associated functions

Publication date: Available online 1 April 2016 Source:Cortex Author(s): Claude J. Bajada, Hamied A. Haroon, Hojjatollah Azadbakht, Geoff J.M. Parker, Matthew A. Lambon Ralph, Lauren L. Cloutman Temporal lobe networks are associated with multiple cognitive domains. Despite an upsurge of interest in connectional neuroanatomy, the terminations of the main fibre tracts in the human brain […]

Full title (Editorial Board Members)

Publication date: March 2016 Source:Advanced Powder Technology, Volume 27, Issue 2 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Y7QkQh via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1MLbNh2 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on […]

Powered by light: Phototrophy and photosynthesis in prokaryotes and its evolution

Publication date: Available online 2 April 2016 Source:Microbiological Research Author(s): Beatrycze Nowicka, Jerzy Kruk Photosynthesis is a complex metabolic process enabling photosynthetic organisms to use solar energy for the reduction of carbon dioxide into biomass. This ancient pathway has revolutionized life on Earth. The most important event was the development of oxygenic photosynthesis. It had […]

A Zebrafish Model of 5q-Syndrome Using CRISPR/Cas9 Targeting RPS14 Reveals a p53-Independent and p53-Dependent Mechanism of Erythroid Failure

Alexandros G. SfakianakisστοEvolution of a geneΠριν από 1 ώρα
[image: S16738527.gif] Publication date: Available online 2 April 2016 *Source:*Journal of Genetics and Genomics Author(s): Jason Ear, Jessica Hsueh, Melinda Nguyen, QingHua Zhang, Victoria Sung, Rajesh Chopra, Kathleen M. Sakamoto, Shuo Lin 5q-syndrome is a distinct form of myelodysplastic syndrome (MDS) where a deletion on chromosome 5 is the underlying cause. MDS is characterized by bone marrow failures, including macrocytic anemia. Genetic mapping and studies using various models support the notion that ribosomal protein S14 (RPS14) is the candidate gene for the erythroid failure... περισσότερα »

Targeted delivery of siRNA to activated T cells via transferrin-polyethylenimine (Tf-PEI) as a potential therapy of asthma

Publication date: 10 May 2016 Source:Journal of Controlled Release, Volume 229 Author(s): Yuran Xie, Na Hyung Kim, Venkatareddy Nadithe, Dana Schalk, Archana Thakur, Ayşe Kılıç, Lawrence G. Lum, David J.P. Bassett, Olivia M. Merkel Asthma is a worldwide health problem. Activated T cells (ATCs) in the lung, particularly T helper 2 cells (Th2), are strongly […]

The release of Doxorubicin from liposomes monitored by MRI and triggered by a combination of US stimuli led to a complete tumor regression in a breast cancer mouse model

Publication date: Available online 2 April 2016 Source:Journal of Controlled Release Author(s): S. Rizzitelli, P. Giustetto, D. Faletto, D. Delli Castelli, S. Aime, E. Terreno The work aimed at developing a novel MRI-based theranostic protocol for improving the anticancer efficacy of a Doxil-like liposomal formulation. The goal was achieved stimulating the intratumor release of the […]

Targeted tumor delivery and controlled release of neuronal drugs with ferritin nanoparticles to regulate pancreatic cancer progression

Publication date: Available online 2 April 2016 Source:Journal of Controlled Release Author(s): Yifeng Lei, Yoh Hamada, Jun Li, Liman Cong, Nuoxin Wang, Ying Li, Wenfu Zheng, Xingyu Jiang Pancreatic cancer is a lethal malignancy whose progression is highly dependent on the nervous microenvironment. This study develops neural drug-loaded ferritin nanoparticles (Ft NPs) to regulate the […]

Fwd: Acta Pharmaceutica Sinica, Year 2016, Issue 03 -New Issue Alert.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 2 ώρες
From: order@email.oriprobe.com Date: April 03, 2016 at 08:09AM [image: 1PHav7d] New Issue TOC Alert *Dear Valued Customer*, [image: 1SchPFA] We are pleased to deliver your requested table of contents alert for *Acta Pharmaceutica Sinica*. Year *2016* Issue *03* is now available on CAOD. *In this issue:* Drug innovation and reverse thinking (药物创新与反向思维) GUO Zong-ru, Iistitute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College ...... page:325-331 Hormesis of drugs for infectious diseases (抗感染药物的毒物兴奋效应浅析) YU Miao, GUO Ying, Beijing Key Laboratory... περισσότερα »

The Tract Terminations in the Temporal Lobe: Their location and associated functions

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Publication date: Available online 1 April 2016 *Source:*Cortex Author(s): Claude J. Bajada, Hamied A. Haroon, Hojjatollah Azadbakht, Geoff J.M. Parker, Matthew A. Lambon Ralph, Lauren L. Cloutman Temporal lobe networks are associated with multiple cognitive domains. Despite an upsurge of interest in connectional neuroanatomy, the terminations of the main fibre tracts in the human brain are yet to be mapped. This information is essential given that neurological, neuroanatomical and computational accounts expect neural functions to be strongly shaped by the pattern of white-matter co... περισσότερα »

Effect of diphenyliodonium hexafluorophosphate on the physical and chemical properties of ethanolic solvated resins containing camphorquinone and 1-phenyl-1,2-propanedione sensitizers as initiators

Publication date: Available online 3 April 2016 Source:Dental Materials Author(s): Diogo Dressano, Alan Rodrigo Palialol, Thaty A. Xavier, Roberto R. Braga, Joe D. Oxman, David C. Watts, Giselle Maria Marchi, Adriano Fonseca Lima ObjectivesTo evaluate the effects of the diphenyliodonium hexafluorophosphate (DPI) on the physical and mechanical properties of solvated dental adhesive resins containing camphorquinone […]

Categorization of common sounds by cochlear implanted and normal hearing adults

Publication date: Available online 2 April 2016 Source:Hearing Research Author(s): E. Collett, M. Marx, P. Gaillard, B. Roby, B. Fraysse, O. Deguine, P. Barone Auditory categorization involves grouping of acoustic events along one or more shared perceptual dimensions which can relate to both semantic and physical attributes. This process involves both high level cognitive processes […]

The Tract Terminations in the Temporal Lobe: Their location and associated functions

Publication date: Available online 1 April 2016 Source:Cortex Author(s): Claude J. Bajada, Hamied A. Haroon, Hojjatollah Azadbakht, Geoff J.M. Parker, Matthew A. Lambon Ralph, Lauren L. Cloutman Temporal lobe networks are associated with multiple cognitive domains. Despite an upsurge of interest in connectional neuroanatomy, the terminations of the main fibre tracts in the human brain […]

The Tract Terminations in the Temporal Lobe: Their location and associated functions

Publication date: Available online 1 April 2016 Source:Cortex Author(s): Claude J. Bajada, Hamied A. Haroon, Hojjatollah Azadbakht, Geoff J.M. Parker, Matthew A. Lambon Ralph, Lauren L. Cloutman Temporal lobe networks are associated with multiple cognitive domains. Despite an upsurge of interest in connectional neuroanatomy, the terminations of the main fibre tracts in the human brain […]

Effect of diphenyliodonium hexafluorophosphate on the physical and chemical properties of ethanolic solvated resins containing camphorquinone and 1-phenyl-1,2-propanedione sensitizers as initiators

Publication date: Available online 3 April 2016 Source:Dental Materials Author(s): Diogo Dressano, Alan Rodrigo Palialol, Thaty A. Xavier, Roberto R. Braga, Joe D. Oxman, David C. Watts, Giselle Maria Marchi, Adriano Fonseca Lima ObjectivesTo evaluate the effects of the diphenyliodonium hexafluorophosphate (DPI) on the physical and mechanical properties of solvated dental adhesive resins containing camphorquinone […]

Full title (Editorial Board Members)

Publication date: March 2016 Source:Advanced Powder Technology, Volume 27, Issue 2 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Y7QkQh via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1MLbNh2 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on […]

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