Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Πέμπτη 19 Μαΐου 2016

OtoRhinoLaryngology & Medicine,New Articles,May 19th,2016,a


The influence of listener training on the perceptual assessment of hypernasality.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
*The influence of listener training on the perceptual assessment of hypernasality.* Codas. 2016 Apr;28(2):141-148 Authors: Oliveira AC, Scarmagnani RH, Fukushiro AP, Yamashita RP Abstract Introduction A high agreement in the perceptual assessment of hypernasality among different listeners is difficult to achieve. Prior listener training and the standardization of analysis criteria may be effective strategies to decrease the effect of perceptual assessment subjectivity and increase the agreement among listeners. Objective To investigate the influence of prior training on agreement... περισσότερα »

Quality of Care Provided by Board-Certified Versus Non-Board-Certified Psychiatrists and Neurologists.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
*Quality of Care Provided by Board-Certified Versus Non-Board-Certified Psychiatrists and Neurologists.* Acad Med. 2016 May 17; Authors: Wallace A, McFarland BH, Selvam N, Sahota G Abstract PURPOSE: To examine associations between board certification of psychiatrists and neurologists and quality-of-care measures, using multilevel models controlling for physician and patient characteristics, and to assess feasibility of linking physician information with patient records to construct quality measures from electronic claims data. METHOD: The authors identified quality measures and ma...περισσότερα »

Science, Not Philosophy, Will Help Deaf and Hard-of-Hearing Children Reach Their Potential.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Science, Not Philosophy, Will Help Deaf and Hard-of-Hearing Children Reach Their Potential.* Pediatrics. 2016 Jan;137(1) Authors: Wake M, Carew P PMID: 26684477 [PubMed - indexed for MEDLINE] from Speech via xlomafota13 on Inoreader http://ift.tt/2523XEZ

What is the potential for context aware communication aids?

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *What is the potential for context aware communication aids?* J Med Eng Technol. 2014;39(7):448-53 Authors: Judge S, Hawley MS, Cunningham S, Kirton A Abstract Use of voice output communication aids (VOCAs) can be a very effective strategy to assist people with speech impairments in communicating. Despite this, people who use communication aids often express frustration with VOCAs-desiring devices that are simpler, quicker and more effective to use. Whilst it is not possible to resolve all these issues with technology, it is a... περισσότερα »

Sound Source Localization and Speech Understanding in Complex Listening Environments by Single-sided Deaf Listeners After Cochlear Implantation.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Sound Source Localization and Speech Understanding in Complex Listening Environments by Single-sided Deaf Listeners After Cochlear Implantation.* Otol Neurotol. 2015 Sep;36(9):1467-71 Authors: Zeitler DM, Dorman MF, Natale SJ, Loiselle L, Yost WA, Gifford RH Abstract OBJECTIVE: To assess improvements in sound source localization and speech understanding in complex listening environments after unilateral cochlear implantation for single-sided deafness (SSD). STUDY DESIGN: Nonrandomized, open, prospective case series.... περισσότερα »

A Structural Equation Modeling Approach to Examining Factors Influencing Outcomes with Cochlear Implant in Mandarin-Speaking Children.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *A Structural Equation Modeling Approach to Examining Factors Influencing Outcomes with Cochlear Implant in Mandarin-Speaking Children.* PLoS One. 2015;10(9):e0136576 Authors: Chen Y, Wong LL, Zhu S, Xi X Abstract OBJECTIVE: To examine the direct and indirect effects of demographical factors on speech perception and vocabulary outcomes of Mandarin-speaking children with cochlear implants (CIs). METHODS: 115 participants implanted before the age of 5 and who had used CI before 1 to 3 years ... περισσότερα »

Response to “Putting the cart before the horse: A cost effectiveness analysis of treatments for stuttering in young children requires evidence that the treatments analyzed were effective”

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
[image: alertIcon.gif] Publication date: Available online 18 May 2016 *Source:*Journal of Communication Disorders Author(s): Caroline de Sonneville-Koedoot, Elly Stolk, Toni Rietveld, Marie-Christine Franken from Speech via xlomafota13 on Inoreader http://ift.tt/1TlBbYm

Vocal dose in teachers: correlation with dysphonia.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
*Vocal dose in teachers: correlation with dysphonia.* Codas. 2016 Apr;28(2):190-192 Authors: Gama AC, Santos JN, Pedra EF, Rabelo AT, Magalhães MC, Casas EB Abstract Teachers are professionals with high prevalence of dysphonia, whose main risk factors are the large work hours in classrooms with the presence of background noise. The purpose of the study was to calculate the phonation time and the cycle dose of teachers with dysphonia and teachers without voice disorders during the class. There were two groups analyzed: five teachers with functional dysphonia were the first group an...περισσότερα »

Voice telerehabilitation in Parkinson's disease.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
*Voice telerehabilitation in Parkinson's disease.* Codas. 2016 Apr;28(2):176-181 Authors: Dias AE, Limongi JC, Barbosa ER, Hsing WT Abstract Parkinson's disease (PD) is a neurodegenerative condition associated with motor, neuropsychological, sensorial, and vocal symptoms. It has been suggested that eventual obstacles faced by many patients to reach speech therapy rehabilitation centers could be overcome with the use of synchronous telerehabilitation (real time) approach employing communication technologies. PURPOSE: To investigate the efficacy of vocal telerehabilitation in PD pa... περισσότερα »

Teacher's voice: vocal tract discomfort symptoms, vocal intensity and noise in the classroom.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
*Teacher's voice: vocal tract discomfort symptoms, vocal intensity and noise in the classroom.* Codas. 2016 Apr;28(2):168-175 Authors: Mendes AL, Lucena BT, De Araújo AM, Melo LP, Lopes LW, Silva MF Abstract OBJECTIVE: To identify a possible correlation between teachers vocal intensity and the noise in the classroom, as well as between vocal intensity and the symptoms of vocal tract discomfort before and after classes. METHODS: 27 Elementary School I teachers participated in the study. We used the questionnaires "Vocal Production Condition of the Teacher" and "Vocal Tract Discomf...περισσότερα »

'Welsh uprising' gave nurses a true voice.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
*'Welsh uprising' gave nurses a true voice.* Nurs Stand. 2016 May 18;30(38):24-25 Authors: Pearce L PMID: 27191430 [PubMed - as supplied by publisher] from Speech via xlomafota13 on Inoreader http://ift.tt/1XBIlgm

Vibrotactile Presentation of Musical Notes to the Glabrous Skin for Adults with Normal Hearing or a Hearing Impairment: Thresholds, Dynamic Range and High-Frequency Perception.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
*Vibrotactile Presentation of Musical Notes to the Glabrous Skin for Adults with Normal Hearing or a Hearing Impairment: Thresholds, Dynamic Range and High-Frequency Perception.* PLoS One. 2016;11(5):e0155807 Authors: Hopkins C, Maté-Cid S, Fulford R, Seiffert G, Ginsborg J Abstract Presentation of music as vibration to the skin has the potential to facilitate interaction between musicians with hearing impairments and other musicians during group performance. Vibrotactile thresholds have been determined to assess the potential for vibrotactile presentation of music to the glabrou... περισσότερα »

Abstract linguistic structure correlates with temporal activity during naturalistic comprehension

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 5 δευτερόλεπτα
[image: S0093934X.gif] Publication date: June–July 2016 *Source:*Brain and Language, Volumes 157–158 Author(s): Jonathan R. Brennan, Edward P. Stabler, Sarah E. Van Wagenen, Wen-Ming Luh, John T. Hale Neurolinguistic accounts of sentence comprehension identify a network of relevant brain regions, but do not detail the information flowing through them. We investigate syntactic information. Does brain activity implicate a computation over hierarchical grammars or does it simply reflect linear order, as in a Markov chain? To address this question, we quantify the cognitive states impli...περισσότερα »

Looking into oropharyngeal dysphagia in older adults.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
*Looking into oropharyngeal dysphagia in older adults.* Nursing. 2016 Jun;46(6):42-43 Authors: PMID: 27192071 [PubMed - as supplied by publisher] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1XBKSaC

Quality of Care Provided by Board-Certified Versus Non-Board-Certified Psychiatrists and Neurologists.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
*Quality of Care Provided by Board-Certified Versus Non-Board-Certified Psychiatrists and Neurologists.* Acad Med. 2016 May 17; Authors: Wallace A, McFarland BH, Selvam N, Sahota G Abstract PURPOSE: To examine associations between board certification of psychiatrists and neurologists and quality-of-care measures, using multilevel models controlling for physician and patient characteristics, and to assess feasibility of linking physician information with patient records to construct quality measures from electronic claims data. METHOD: The authors identified quality measures and ma...περισσότερα »

A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: the TRANSFoRm study protocol.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: the TRANSFoRm study protocol.* Implement Sci. 2015;10:15 Authors: Mastellos N, Andreasson A, Huckvale K, Larsen M, Curcin V, Car J, Agreus L, Delaney B Abstract BACKGROUND: Opportunistic recruitment is a highly laborious and time-consuming process that is currently performed manually, increasing the workload of already busy practitioners and resulting in m... περισσότερα »

Residual fundus or neofundus after laparoscopic sleeve gastrectomy: is fundectomy safe and effective as revision surgery?

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *Residual fundus or neofundus after laparoscopic sleeve gastrectomy: is fundectomy safe and effective as revision surgery?* Surg Endosc. 2015 Oct;29(10):2899-903 Authors: Silecchia G, De Angelis F, Rizzello M, Albanese A, Longo F, Foletto M Abstract INTRODUCTION: Up to 30 % of patients who have undergone laparoscopic sleeve gastrectomy require revision surgery for inadequate weight loss, weight regain, and/or the development of severe upper gastrointestinal symptoms. The aim of this retrospective study was to evalu... περισσότερα »

A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: the TRANSFoRm study protocol.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: the TRANSFoRm study protocol.* Implement Sci. 2015;10:15 Authors: Mastellos N, Andreasson A, Huckvale K, Larsen M, Curcin V, Car J, Agreus L, Delaney B Abstract BACKGROUND: Opportunistic recruitment is a highly laborious and time-consuming process that is currently performed manually, increasing the workload of already busy practitioners and resulting in m... περισσότερα »

Residual fundus or neofundus after laparoscopic sleeve gastrectomy: is fundectomy safe and effective as revision surgery?

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *Residual fundus or neofundus after laparoscopic sleeve gastrectomy: is fundectomy safe and effective as revision surgery?* Surg Endosc. 2015 Oct;29(10):2899-903 Authors: Silecchia G, De Angelis F, Rizzello M, Albanese A, Longo F, Foletto M Abstract INTRODUCTION: Up to 30 % of patients who have undergone laparoscopic sleeve gastrectomy require revision surgery for inadequate weight loss, weight regain, and/or the development of severe upper gastrointestinal symptoms. The aim of this retrospective study was to evalu... περισσότερα »

A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: the TRANSFoRm study protocol.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: the TRANSFoRm study protocol.* Implement Sci. 2015;10:15 Authors: Mastellos N, Andreasson A, Huckvale K, Larsen M, Curcin V, Car J, Agreus L, Delaney B Abstract BACKGROUND: Opportunistic recruitment is a highly laborious and time-consuming process that is currently performed manually, increasing the workload of already busy practitioners and resulting in m... περισσότερα »

Residual fundus or neofundus after laparoscopic sleeve gastrectomy: is fundectomy safe and effective as revision surgery?

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *Residual fundus or neofundus after laparoscopic sleeve gastrectomy: is fundectomy safe and effective as revision surgery?* Surg Endosc. 2015 Oct;29(10):2899-903 Authors: Silecchia G, De Angelis F, Rizzello M, Albanese A, Longo F, Foletto M Abstract INTRODUCTION: Up to 30 % of patients who have undergone laparoscopic sleeve gastrectomy require revision surgery for inadequate weight loss, weight regain, and/or the development of severe upper gastrointestinal symptoms. The aim of this retrospective study was to evalu... περισσότερα »

Cortical Auditory-Evoked Potentials in Response to Multitone Stimuli in Hearing-Impaired Adults

from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/209uzjV via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Validation of the Home Hearing Test™

from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1VaFZVo via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Inflammatory biomarkers and risk of cancer in 84,000 individuals from the general population

Abstract Inflammation and cancer are tightly linked. This study tests the hypothesis that an inflammatory score based on plasma levels of C-reactive protein (CRP) and fibrinogen and whole blood leukocyte count is associated with risk of colorectal, lung, breast, and prostate cancer. A score ranging from none through three elevated biomarkers was constructed in 84,000 […]

Gastrointestinal and liver disease in Adult Life After Childhood Cancer in Scandinavia: A population-based cohort study

Abstract Survival after childhood cancer diagnosis has remarkably improved, but emerging evidence suggests that cancer-directed therapy may have adverse gastrointestinal late effects. We aimed to comprehensively assess the frequency of gastrointestinal and liver late effects among childhood cancer survivors and compare this frequency with the general population. Our population-based cohort study included all one-year survivors […]

Modulation of tumor eIF4E by antisense inhibition: A phase I/II translational clinical trial of ISIS 183750 – an antisense oligonucleotide against eIF4E – in combination with irinotecan in solid tumors and irinotecan-refractory colorectal cancer

Abstract The eukaryotic translation initiation factor 4E (eIF4E) is a potent oncogene that is found to be dysregulated in 30% of human cancer, including colorectal carcinogenesis (CRC). ISIS 183750 is a second-generation antisense oligonucleotide (ASO) designed to inhibit the production of the eIF4E protein. In preclinical studies we found that EIF4e ASOs reduced expression of […]

Clinicopathogenomic analysis of mismatch repair proficient colorectal adenocarcinoma uncovers novel prognostic subgroups with differing patterns of genetic evolution

Abstract Cancer somatic genetic evolution is a direct contributor to heterogeneity at the clonal and molecular level in colorectal adenocarcinoma (COAD). We sought to determine the extent to which genetic evolution may be detected in COAD in routinely obtained single clinical specimens and establish clinical significance with regard to clinicopathologic and outcome data. 123 cases […]

Knockdown of COUP-TFII inhibits cell proliferation and induces apoptosis through upregulating BRCA1 in renal cell carcinoma cells

Abstract COUP-TFII belongs to the nuclear receptor family, which is highly expressed in many kinds of tumors. Previous studies have shown that COUP-TFII can promote tumor progression through regulating tumor angiogenesis and cell proliferation and migration of certain cancer cells. However, the function of COUP-TFII in renal cell carcinoma (RCC) is not clear. Here we […]

Integrative functional genomic delineation of the cascades of transcriptional changes involved in hepatocellular carcinoma progression

Abstract Development of targeted therapeutics is still at its early stage for hepatocellular carcinoma (HCC) due to the incomplete understanding of the confounding regulations at signaling pathway level. In this investigation, gene co-expression based networking and integrative functional genomic modeling of HCC mRNA profiles as signaling processes were employed to understand the complex signaling cascades […]

Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH

Abstract Germline mutations in the DNA base excision repair gene MUTYH are known to increase a carrier’s risk of colorectal cancer. However, the risks of other (extracolonic) cancers for MUTYH mutation carriers are not well defined. We identified 266 probands (91% Caucasians) with a MUTYH mutation (41 biallelic and 225 monoallelic) from the Colon Cancer […]

Long-term outcomes of simultaneous guided bone regeneration using native and cross-linked collagen membranes after 8 years

Abstract Objectives To assess the clinical outcomes of simultaneous guided bone regeneration using native (CM) and cross-linked (VN) collagen membranes at 8 years. Materials and methods A total of n = 19 patients (19 implants) were available for the analysis. Each subject had received a simultaneous grafting of dehiscence-type defects using a natural bone mineral […]

Surgical outcomes of the endoscopic endonasal transsphenoidal approach for large and giant pituitary adenomas: institutional experience with special attention to approach-related complications.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 23 δευτερόλεπτα
*Surgical outcomes of the endoscopic endonasal transsphenoidal approach for large and giant pituitary adenomas: institutional experience with special attention to approach-related complications.* Arq Neuropsiquiatr. 2016 May;74(5):388-395 Authors: Constantino ER, Leal R, Ferreira CC, Acioly MA, Landeiro JA Abstract Objective In this study, we investigate our institutional experience of patients who underwent endoscopic endonasal transsphenoidal approach for treatment of large and giant pituitary adenomas emphasizing the surgical results and approach-related complications. Method T...περισσότερα »

Use of a platelet-rich fibrin membrane to repair traumatic tympanic membrane perforations: a comparative study.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 23 δευτερόλεπτα
*Use of a platelet-rich fibrin membrane to repair traumatic tympanic membrane perforations: a comparative study.* Acta Otolaryngol. 2016 May 18;:1-7 Authors: Gür ÖE, Ensari N, Öztürk MT, Boztepe OF, Gün T, Selçuk ÖT, Renda L Abstract OBJECTIVES: (1) To evaluate the effects of a platelet-rich fibrin (PRF) membrane in the repair of traumatic tympanic membrane (TM) perforations; and (2) to compare the use of a PRF membrane with the paper patch technique with regard to recovery rates, healing time, and correction of the mean air-bone gap. METHODS: A randomized, prospective analysis wa...περισσότερα »

Hearing impairment, cochlear morphology, and peroxynitrite (ONOO(-)) formation in adult and aging NOS II knockout mice.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 23 δευτερόλεπτα
*Hearing impairment, cochlear morphology, and peroxynitrite (ONOO(-)) formation in adult and aging NOS II knockout mice.* Acta Otolaryngol. 2016 May 18;:1-8 Authors: Labbé D, Bloch W, Schick B, Michel O Abstract CONCLUSION: Nitric oxide synthase (NOS) II induction is a protective mechanism against age-related degeneration of the cochlea. OBJECTIVES: An induction of NOS II has been described in different inner ear pathologies. The objective was to examine the role of NOS II in age-related degeneration of the cochlea. METHODS: The hearing ability in adult and aging NOS II knockout mi...περισσότερα »

Prognostic impact of perineural invasion in hypopharyngeal squamous cell carcinoma.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 23 δευτερόλεπτα
*Prognostic impact of perineural invasion in hypopharyngeal squamous cell carcinoma.* Acta Otolaryngol. 2016 May 18;:1-5 Authors: Joo YH, Cho KJ, Lee YS, Kim SY, Kim MS Abstract OBJECTIVES: The aim of this study was to evaluate the role of PNI in HPSCC. METHODS: The medical records of 105 patients who underwent surgery-based treatment for HPSCC were reviewed. Clinicopathologic parameters including disease-specific survival were correlated with PNI. RESULTS: PNI was identified in 27 of the 105 (25.7%) cases of HPSCC. Correlation analysis demonstrated that PNI in HPSCC was significan... περισσότερα »

Energies, Vol. 9, Pages 381: An Event-Triggered Online Energy Management Algorithm of Smart Home: Lyapunov Optimization Approach

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 35 δευτερόλεπτα
[image: ag] As an important component of the smart grid on the user side, a home energy management system is the core of optimal operation for a smart home. In this paper, the energy scheduling problem for a household equipped with photovoltaic devices was investigated. An online energy management algorithm based on event triggering was proposed. The Lyapunov optimization method was adopted to schedule controllable load in the household. Without forecasting related variables, real-time decisions were made based only on the current information. Energy could be rapidly regulated unde...περισσότερα »

Sensors, Vol. 16, Pages 709: A Low-Noise Transimpedance Amplifier for BLM-Based Ion Channel Recording

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 35 δευτερόλεπτα
High-throughput screening (HTS) using ion channel recording is a powerful drug discovery technique in pharmacology. Ion channel recording with planar bilayer lipid membranes (BLM) is scalable and has very high sensitivity. A HTS system based on BLM ion channel recording faces three main challenges: (i) design of scalable microfluidic devices; (ii) design of compact ultra-low-noise transimpedance amplifiers able to detect currents in the pA range with bandwidth >10 kHz; (iii) design of compact, robust and scalable systems that integrate these two elements. This paper presents a low-... περισσότερα »

Sinusitis, Vol. 1, Pages 65-75: LTD4 and TGF-β1 Induce the Expression of Metalloproteinase-1 in Chronic Rhinosinusitis via a Cysteinyl Leukotriene Receptor 1-Related Mechanism

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 35 δευτερόλεπτα
Background: Cysteinyl leukotrienes (CysLTs) play a crucial role in the pathogenesis of airway remodeling. The use of CysLTs receptor antagonists has been included in the management of asthma and rhinitis. However, despite the action of these compounds on leukotriene production has been well documented, their role in airway remodeling remains unclear. Objective: We aimed to investigate the capability of the leukotriene receptor antagonist Montelukast to inhibit MMPs release after CysLTs stimulation in nasal tissue fibroblasts. Methods: Fibroblasts were isolated from sinunasal tissu... περισσότερα »

Cardiac troponin T is necessary for normal development in the embryonic chick heart

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
Abstract The heart is the first functioning organ to develop during embryogenesis. The formation of the heart is a tightly regulated and complex process, and alterations to its development can result in congenital heart defects. Mutations in sarcomeric proteins, such as alpha myosin heavy chain and cardiac alpha actin, have now been associated with congenital heart defects in humans, often with atrial septal defects. However, cardiac troponin T (cTNT encoded by gene *TNNT2*) has not. Using gene-specific antisense oligonucleotides, we have investigated the role of cTNT in chick card... περισσότερα »

Abstract: PRS AAPS Oral Proofs 2016

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
No abstract available from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/209hpn7 via IFTTT

Abstract: PRS PSRC Poster Proofs PSRC 2016

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
No abstract available from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1ONd1ti via IFTTT

Cicatricial Ectropion With Topical 5% Fluorouracil Cream.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
No abstract available from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/27CBF64 via IFTTT

Reconstruction of a Hand Web Space Defect.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
No abstract available from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1Tp59Nx via IFTTT

Histologic Findings of Tumor Lysis in Advanced Basal Cell Carcinoma Treated With Vismodegib.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
No abstract available from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/27CBCXT via IFTTT

Laser-Assisted Drug Delivery.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
BACKGROUND: Laser-assisted drug delivery (LADD) is an evolving new therapy with many possible applications as a highly targeted customizable method for distribution of drugs within the skin. LADD offers the advantages of accessibility, noninvasiveness, compliance, safety, and effectiveness. OBJECTIVE: To review the available literature regarding LADD. METHODS: A MEDLINE search was performed on LADD from 1989 to 2015, and the results are summarized. Practical applications of these procedures are also discussed. RESULTS: Reports of the use of ablative, nonablative, and fractional laser... περισσότερα »

Pulsed Dye Laser Treatment of Multiple Common Acquired Melanocytic Nevi: A Novel Approach.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
No abstract available from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/27CBFTO via IFTTT

Advanced Scalp Measurement Using a Phototrichogram With a Protractor and Tapeline.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
No abstract available from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1Tp4RGh via IFTTT

Superficial Acral Fibromyxoma (Digital Fibromyxoma): A Novel Treatment Approach Using Mohs Micrographic Surgery for a Recurrence-Prone Digital Tumor.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
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Commentary on Neodymium-Doped Yttrium Aluminium Garnet Laser Treatment of Pediatric Venous Malformation in Oral Cavity.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
No abstract available from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1Tp5iQQ via IFTTT

Health-related quality of life in patients with spinal dural arteriovenous fistulae

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
Abstract Neurological improvement in patients with spinal dural arteriovenous fistulae (SDAVF) is often partial even after adequate treatment. While treatment outcomes have been evaluated primarily on the basis of the postoperative changes in neurological deficits, outcome measures should also reflect the patient-reported outcome (PRO). We conducted a health-related quality of life (HRQOL) survey in 52 SDAVF patients; 33 (63.5%) completed the short-form 36 Health Survey (SF-36) questionnaire. They were 25 males and 8 females ranging in age from 47 to 85 years (mean age 70.0 years).... περισσότερα »

The masaryk hospital extracranial–intracranial bypass study

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
Abstract Patients with symptomatic internal carotid artery (ICA) occlusion with haemodynamic impairment are at higher risk of ischaemic stroke, and they require treatment. There are two main options: the best medical treatment and an extracranial–intracranial bypass. The aims of this study are to analyse the 30-day and 2-year risk of stroke and death in patients with extracranial–intracranial bypass performed by our department and to compare our results with major published studies. This retrospective study enrolled patients who underwent surgery from 1998 to 2012. Inclusion criteri... περισσότερα »

Managing missed lower extremity compartment syndrome in the physiologically stable patient: A systematic review and lessons from a level I trauma center.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Background: Decompressing an acute lower extremity compartment syndrome salvages muscle and nerve and preserves limb function. However reperfusion of ischemic tissue causes a systemic insult that can be life-threatening. Hence, the management of missed acute lower limb compartment syndrome remains controversial. The aim of this study was to evaluate the literature and, together with our own experience from a level 1 trauma centre, clarify the management of missed compartment syndrome in the physiologically stable patient. Methods: Pubmed, EMBASE, MEDLINE, the Cochrane database of sy... περισσότερα »

Repainting the ceiling: Do patient safety and satisfaction initiatives make things safer or more satisfying?.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
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A case of trapped lung by a fractured rib.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
No abstract available from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1U0KHSU

Emergent non-image guided REBOA catheter placement: A cadaver-based study.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Background: Emergent REBOA(Resuscitative Endovascular Balloon Occlusion of the Aorta) insertion for critically injured patients in hemorrhagic shock is performed blindly with fluoroscopic imaging confirmation. The aim of this study was to determine a reliable method for initial REBOA catheter insertion with balloon deployment between the left subclavian artery takeoff and celiac trunk. Methods: Human cadaver study. External surface (sternal notch, mid-sternum, xiphoid) and intravascular (left subclavian artery(LSA), celiac trunk(CT)) landmarks were measured from standardized left an...περισσότερα »

Correlation between laboratory coagulation testing and thromboelastometry is modified during management of trauma patients.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Background: Thromboelastometry (ROTEM(R)) is increasingly being used to make a diagnosis of coagulopathy and to guide hemostatic therapy (HT). Although ROTEM(R) parameters and standard laboratory test (SLT) correlated well before administration of HT, it is not known if this correlation persists after hemostatic resuscitation. Methods: A retrospective analysis of prospectively collected data from a trauma registry (2011-2014) was performed. All patients having a ROTEM(R) analysis were included. ROTEM(R) parameters (clotting time, CT and clot amplitude at 5 min, A5) were determined a...περισσότερα »

Delayed presentation of pulmonary hernia following surgical stabilization of severe rib fractures.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
No abstract available from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Tqro74

Identifying potential utility of REBOA: An autopsy study.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Background: Resuscitative thoracotomy (RT) has been the standard therapy in patients with acute arrest due to hemorrhagic shock. However; with the development of resuscitative endovascular balloon occlusion of the aorta (REBOA), its role as a potential adjunct to a highly morbid intervention like RT is being discussed. The aim of this study was to identify patients that most likely would have potentially benefitted from REBOA use based on autopsy findings. Methods: We performed a four-year retrospective review of all RT performed at our Level I trauma center. Patients with in-hospita...περισσότερα »

Contemporary management of civilian penetrating cervicothoracic arterial injuries.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Background: The management of arterial injury at the thoracic outlet has long hinged on the fundamental principles of extensile exposure and vascular anastomosis. Nonetheless, treatment options for such injuries have evolved to include both endovascular stent placement and temporary vascular shunts. The purpose of this study was to evaluate our recent experience with penetrating cervicothoracic arterial injuries in light of these developments in trauma care. Methods: Patients with penetrating injuries to the innominate, carotid, subclavian, or axillary arteries managed at a single c... περισσότερα »

Reducing acute kidney injury due to vancomycin in trauma patients.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Background: Supratherapeutic vancomycin trough levels are common after trauma and associated with both increased acute kidney injury (AKI) and mortality. We sought to limit the adverse effects of vancomycin in trauma patients through more frequent trough monitoring. Methods: Beginning in January 2011, trauma patients treated with vancomycin had trough levels (VT) monitored daily until steady-state was reached. Trauma patients admitted from January 2011 to May 2015 (POST) were compared to those admitted from January 2006 to December 2010 (PRE). Inclusion criteria required administrat...περισσότερα »

Limiting chest computed tomography in the evaluation of pediatric thoracic trauma.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Background: Computed tomography (CT) chest is overused in blunt pediatric thoracic trauma. CT chest adds to the diagnosis of thoracic injury but rarely changes patient management. We sought to identify a subset of blunt pediatric trauma patients who would benefit from a screening CT chest based on their admission chest X-ray (CXR) findings. We hypothesize that limiting CT chest to patients with an abnormal mediastinal silhouette identifies intra-thoracic vascular injuries not otherwise seen on CXR. Methods: All blunt trauma activations that underwent an admission CXR at our level 1 ...περισσότερα »

A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: the TRANSFoRm study protocol.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: the TRANSFoRm study protocol.* Implement Sci. 2015;10:15 Authors: Mastellos N, Andreasson A, Huckvale K, Larsen M, Curcin V, Car J, Agreus L, Delaney B Abstract BACKGROUND: Opportunistic recruitment is a highly laborious and time-consuming process that is currently performed manually, increasing the workload of already busy practitioners and resulting in ... περισσότερα »

Residual fundus or neofundus after laparoscopic sleeve gastrectomy: is fundectomy safe and effective as revision surgery?

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *Residual fundus or neofundus after laparoscopic sleeve gastrectomy: is fundectomy safe and effective as revision surgery?* Surg Endosc. 2015 Oct;29(10):2899-903 Authors: Silecchia G, De Angelis F, Rizzello M, Albanese A, Longo F, Foletto M Abstract INTRODUCTION: Up to 30 % of patients who have undergone laparoscopic sleeve gastrectomy require revision surgery for inadequate weight loss, weight regain, and/or the development of severe upper gastrointestinal symptoms. The aim of this retrospective study was to eval... περισσότερα »

Prevention of Postoperative Cerebrospinal Fluid Leaks After Translabyrinthine Tumor Resection With Resorbable Mesh Cranioplasty.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Prevention of Postoperative Cerebrospinal Fluid Leaks After Translabyrinthine Tumor Resection With Resorbable Mesh Cranioplasty.* Otol Neurotol. 2015 Sep;36(9):1537-42 Authors: Hunter JB, Sweeney AD, Carlson ML, Wanna GB, Rivas A, Weaver KD, Chambless LB, Thompson RS, Haynes DS, Bennett ML Abstract OBJECTIVES: To evaluate the effectiveness of resorbable mesh cranioplasty at reducing postoperative cerebrospinal fluid (CSF) leak and pseudomeningocele formation after translabyrinthine tumor resection. STUDY DESIGN: C...περισσότερα »

The Expanding Role of Audiology Telepractice

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
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Materials, Vol. 9, Pages 388: Evaluation of Microstructure and Transport Properties of Deteriorated Cementitious Materials from Their X-ray Computed Tomography (CT) Images

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Pore structure, tortuosity and permeability are considered key properties of porous materials such as cement pastes to understand their long-term durability performance. Three-dimensional image analysis techniques were used in this study to quantify pore size, effective porosity, tortuosity, and permeability from the X-ray computed tomography (CT) images of deteriorated pastes that were subjected to accelerated leaching test. X-ray microtomography is a noninvasive three-dimensional (3D) imaging technique which has been recently gaining attention for material characterization. Coup...περισσότερα »

Sensors, Vol. 16, Pages 724: A Continuous Liquid-Level Sensor for Fuel Tanks Based on Surface Plasmon Resonance

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
A standard problem in large tanks at oil refineries and petrol stations is that water and fuel usually occupy the same tank. This is undesirable and causes problems such as corrosion in the tanks. Normally, the water level in tanks is unknown, with the problems that this entails. We propose herein a method based on surface plasmon resonance (SPR) to detect in real time the interfaces in a tank which can simultaneously contain water, gasoline (or diesel) and air. The plasmonic sensor is composed of a hemispherical glass prism, a magnesium fluoride layer, and a gold layer. We have o... περισσότερα »

Energies, Vol. 9, Pages 383: An Intelligent Sensor for the Ultra-High-Frequency Partial Discharge Online Monitoring of Power Transformers

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Ultra-high-frequency (UHF) partial discharge (PD) online monitoring is an effective way to inspect potential faults and insulation defects in power transformers. The construction of UHF PD online monitoring system is a challenge because of the high-frequency and wide-frequency band of the UHF PD signal. This paper presents a novel, intelligent sensor for UHF PD online monitoring based on a new method, namely a level scanning method. The intelligent sensor can directly acquire the statistical characteristic quantities and is characterized by low cost, few data to output and transmi... περισσότερα »

Energies, Vol. 9, Pages 384: Cobalt-Based Electrolytes for Dye-Sensitized Solar Cells: Recent Advances towards Stable Devices

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Redox mediators based on cobalt complexes allowed dye-sensitized solar cells (DSCs) to achieve efficiencies exceeding 14%, thus challenging the emerging class of perovskite solar cells. Unfortunately, cobalt-based electrolytes demonstrate much lower long-term stability trends if compared to the traditional iodide/triiodide redox couple. In view of the large-scale commercialization of cobalt-based DSCs, the scientific community has recently proposed various approaches and materials to increase the stability of these devices, which comprise gelling agents, crosslinked polymeric matr... περισσότερα »

END-PROCESSING NUCLEASES AND PHOSPHODIESTERASES: AN ELITE SUPPORTING CAST FOR THE NON-HOMOLOGOUS END JOINING PATHWAY OF DNA DOUBLE-STRAND BREAK REPAIR

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 18 May 2016 *Source:*DNA Repair Author(s): Vijay Menon, Lawrence Povirk Nonhomologous end joining (NHEJ) is an error-prone DNA double-strand break repair pathway that is active throughout the cell cycle. A substantial fraction of NHEJ repair events show deletions and, less often, insertions in the repair joints, suggesting an end-processing step comprising the removal of mismatched or damaged nucleotides by nucleases and other phosphodiesterases, as well as subsequent strand extension by polymerases. A wide range of nucleases, including Artemis, Me... περισσότερα »

ALKBHs-facilitated RNA modifications and de-modifications

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 17 May 2016 *Source:*DNA Repair Author(s): Endalkachew Alemu, Chuan He, Arne Klungland The AlkB gene that protects E.coli against methylation damage to DNA was identified more than 3 decades ago. 20 years later, the AlkB protein was shown to catalyze repair of methylated DNA base lesions by oxidative demethylation. Two human AlkB homologs were characterized with a similar DNA repair activity and seven additional human AlkB homologs were identified based on sequence homology. All these dioxygenases, ALKBH1-8 and FTO, contain a conserved α-ketoglutar... περισσότερα »

Polymers, Vol. 8, Pages 200: Thermogel-Coated Poly(ε-Caprolactone) Composite Scaffold for Enhanced Cartilage Tissue Engineering

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: ag] A three-dimensional (3D) composite scaffold was prepared for enhanced cartilage tissue engineering, which was composed of a poly(ε-caprolactone) (PCL) backbone network and a poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide) (PLGA–PEG–PLGA) thermogel surface. The composite scaffold not only possessed adequate mechanical strength similar to native osteochondral tissue as a benefit of the PCL backbone, but also maintained cell-friendly microenvironment of the hydrogel. The PCL network with homogeneously-controlled pore size and total p...περισσότερα »

Energies, Vol. 9, Pages 385: A Study on Price-Based Charging Strategy for Electric Vehicles on Expressways

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
With the large-scale adoption of electric vehicles (EVs) on expressways, the exploration of a guiding-based charging method to effectively adjust interactions between EVs and the fast charging stations (CSs) is urgently needed. This paper proposes a status-of-use (SOU) price-based charging strategy that can motivate users to charge in advance. A queuing model for a CS cluster was established to verify the effectiveness of the strategy, and then a simulation of traveling and charging conditions of 12,000 pure EVs on the road network from 0:00 to 24:00 was performed according to the ... περισσότερα »

Materials, Vol. 9, Pages 392: Optimising Ambient Setting Bayer Derived Fly Ash Geopolymers

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
The Bayer process utilises high concentrations of caustic and elevated temperature to liberate alumina from bauxite, for the production of aluminium and other chemicals. Within Australia, this process results in 40 million tonnes of mineral residues (Red mud) each year. Over the same period, the energy production sector will produce 14 million tonnes of coal combustion products (Fly ash). Both industrial residues require impoundment storage, yet combining some of these components can produce geopolymers, an alternative to cement. Geopolymers derived from Bayer liquor and fly ash h... περισσότερα »

Materials, Vol. 9, Pages 390: Influence of Hybridizing Flax and Hemp-Agave Fibers with Glass Fiber as Reinforcement in a Polyurethane Composite

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
In this study, six combinations of flax, hemp, and glass fiber were investigated for a hybrid reinforcement system in a polyurethane (PU) composite. The natural fibers were combined with glass fibers in a PU composite in order to achieve a better mechanical reinforcement in the composite material. The effect of fiber hybridization in PU composites was evaluated through physical and mechanical properties such as water absorption (WA), specific gravity (SG), coefficient of linear thermal expansion (CLTE), flexural and compression properties, and hardness. The mechanical properties o... περισσότερα »

Sustainability, Vol. 8, Pages 491: Abandonment, Ecological Assembly and Public Health Risks in Counter-Urbanizing Cities

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: ag] Urban landscapes can be transformed by widespread abandonment from population and economic decline. Ecological assembly, sometimes referred to as "greening", following abandonment can yield valuable ecosystem services, but also can pose a risk to public health. Abandonment can elevate zoonotic vector-borne disease risk by favoring the hyperabundance of commensal pests and pathogen vectors. Though greater biodiversity in abandoned areas can potentially dilute vector-borne pathogen transmission, "greening" can elevate transmission risk by increasing movement of pathogen v...περισσότερα »

Sensors, Vol. 16, Pages 729: Systematic Error Modeling and Bias Estimation

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
This paper analyzes the statistic properties of the systematic error in terms of range and bearing during the transformation process. Furthermore, we rely on a weighted nonlinear least square method to calculate the biases based on the proposed models. The results show the high performance of the proposed approach for error modeling and bias estimation. from #Medicine via ola Kala on Inoreader http://ift.tt/1W3Vlfl via IFTTT

Applied Sciences, Vol. 6, Pages 157: Chord Recognition Based on Temporal Correlation Support Vector Machine

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: ag] In this paper, we propose a method called temporal correlation support vector machine (TCSVM) for automatic major-minor chord recognition in audio music. We first use robust principal component analysis to separate the singing voice from the music to reduce the influence of the singing voice and consider the temporal correlations of the chord features. Using robust principal component analysis, we expect the low-rank component of the spectrogram matrix to contain the musical accompaniment and the sparse component to contain the vocal signals. Then, we extract a new loga...περισσότερα »

Crystals, Vol. 6, Pages 61: Colloidal Photonic Crystals Containing Silver Nanoparticles with Tunable Structural Colors

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: ag] Polystyrene (PS) colloidal photonic crystals (CPhCs) containing silver nanoparticles (AgNPs) present tunable structural colors. PS CPhC color films containing a high concentration of AgNPs were prepared using self-assembly process through gravitational sedimentation method. High-concentration AgNPs were deposited on the bottom of the substrate and acted as black materials to absorb background and scattering light. Brilliant structural colors were enhanced because of the absorption of incoherent scattering light, and color saturation was increased by the distribution Ag...περισσότερα »

Energies, Vol. 9, Pages 386: Modelling, Testing and Analysis of a Regenerative Hydraulic Shock Absorber System

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
To improve vehicle fuel economy whilst enhancing road handling and ride comfort, power generating suspension systems have recently attracted increased attention in automotive engineering. This paper presents our study of a regenerative hydraulic shock absorber system which converts the oscillatory motion of a vehicle suspension into unidirectional rotary motion of a generator. Firstly a model which takes into account the influences of the dynamics of hydraulic flow, rotational motion and power regeneration is developed. Thereafter the model parameters of fluid bulk modulus, motor ... περισσότερα »

A systematic review of community based hepatitis C treatment

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
BMC Infectious Diseases from #Medicine via ola Kala on Inoreader http://ift.tt/1ONsTMq via IFTTT

On-treatment HCV RNA as a predictor of sustained virologic response in HCV genotype 3–infected patients treated with daclatasvir and sofosbuvir

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Liver International from #Medicine via ola Kala on Inoreader http://ift.tt/209qXhL via IFTTT

A systematic review of community based hepatitis C treatment

BMC Infectious Diseases from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1ONsTMq via IFTTT

Hepatitis B virus expression and replication in ovum and the influencing factors

Saudi Journal of Gastroenterology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1ONsWHU via IFTTT

A phase II study of a modified FOLFOX6 regimen as neoadjuvant chemotherapy for locally advanced gastric cancer

British Journal of Cancer from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/209qCvK via IFTTT

Preclinical development of Ramizol, an antibiotic belonging to a new class, for the treatment of Clostridium difficile colitis

The Journal of Antibiotics from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1ONt1vq via IFTTT

Efficacy of double-coated probiotics for irritable bowel syndrome: a randomized double-blind controlled trial

Journal of Gastroenterology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/209rws3 via IFTTT

Intensity of adjuvant chemotherapy regimens and grade III–V toxicities among elderly stage III colon cancer patients

European Journal of Cancer from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1ONsTvJ via IFTTT

An open-label randomized control study to compare the efficacy of vitamin E versus ursodeoxycholic acid in nondiabetic and noncirrhotic Indian NAFLD patients

Saudi Journal of Gastroenterology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1ONsXf4 via IFTTT

Appropriateness of testing for anti-tumor necrosis factor agent and antibody concentrations, and interpretation of results

Clinical Gastroenterology and Hepatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/209r9xy via IFTTT

Full-length LGR5-positive cells have chemoresistant characteristics in colorectal cancer

British Journal of Cancer from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1ONt5eu via IFTTT

Ferric maltol in iron deficiency anaemia in patients with inflammatory bowel disease

Drugs & Therapy Perspectives from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1ONsXMc via IFTTT

Risk of advanced neoplasia in first-degree relatives with colorectal cancer: a large multicenter cross-sectional study

PLoS Medicine from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1U14W0e via IFTTT

Dietary total antioxidant capacity and pancreatic cancer risk: an Italian case–control study

British Journal of Cancer from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1U0VDjy via IFTTT

Resistance analyses of japanese hepatitis c-infected patients receiving sofosbuvir or ledipasvir/sofosbuvir containing regimens in phase 3 studies

Journal of Viral Hepatitis from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1XBBTpG via IFTTT

Randomized clinical trial comparing ten day concomitant and sequential therapies for Helicobacter pylori eradication in a high clarithromycin resistance area

European Journal of Internal Medicine from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1U0VyfV via IFTTT

Dyspnoe, Abgeschlagenheit, Giemen: Ursache war ein Lungentumor

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Seltener Tumor im fortgeschrittenen Stadium Ein inflammatorischer myofibroblastärer Tumors der Lunge (IMT) im fortgeschrittenen Stadium führte bei endobronchialem Wachstum zu einer kompletten Obstruktion des linken Oberlappenbronchus und imponierte im Röntgenthorax als eine Totalatelektase der linken Lunge. from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1rVUy3o via IFTTT

Evaluation and Enhancement of Calibration in the American College of Surgeons NSQIP Surgical Risk Calculator

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
The ACS NSQIP Surgical Risk Calculator has been widely adopted as a decision aid and informed consent tool by surgeons and patients. Previous evaluations showed excellent discrimination and combined discrimination and calibration, but model calibration alone, and potential benefits of recalibration, were not explored. Because lack of calibration can lead to systematic errors in assessing… Continue reading Evaluation and Enhancement of Calibration in the American College of Surgeons NSQIP Surgical Risk Calculator

Cell Fate and Differentiation of Bone Marrow Mesenchymal Stem Cells

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Osteoblasts and bone marrow adipocytes originate from bone marrow mesenchymal stem cells (BMMSCs) and there appears to be a reciprocal relationship between adipogenesis and osteoblastogenesis. Alterations in the balance between adipogenesis and osteoblastogenesis in BMMSCs wherein adipogenesis is increased relative to osteoblastogenesis are associated with decreased bone quality and quantity. Several proteins have been reported… Continue reading Cell Fate and Differentiation of Bone Marrow Mesenchymal Stem Cells

A Randomization Approach for Stochastic Workflow Scheduling in Clouds

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
In cloud systems consisting of heterogeneous distributed resources, scheduling plays a key role to obtain good performance when complex applications are run. However, there is unavoidable error in predicting individual task execution times and data transmission times. When this error is being not negligible, deterministic scheduling approaches (i.e., scheduling based on accurate time prediction) may… Continue reading A Randomization Approach for Stochastic Workflow Scheduling in Clouds

CAR T Cell Therapy: A Game Changer in Cancer Treatment

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
The development of novel targeted therapies with acceptable safety profiles is critical to successful cancer outcomes with better survival rates. Immunotherapy offers promising opportunities with the potential to induce sustained remissions in patients with refractory disease. Recent dramatic clinical responses in trials with gene modified T cells expressing chimeric antigen receptors (CARs) in B-cell malignancies… Continue reading CAR T Cell Therapy: A Game Changer in Cancer Treatment

Structure, Mechanism, and Application of Vacuum Insulation Panels in Chinese Buildings

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Thermal insulation is one of the most used approaches to reduce energy consumption in buildings. Vacuum insulation panels (VIPs) are new thermal insulation materials that have been used in the domestic and overseas market in the last 20 years. Due to the vacuum thermal insulation technology of these new materials, their thermal conductivity can be… Continue reading Structure, Mechanism, and Application of Vacuum Insulation Panels in Chinese Buildings

Erythropoietin Dose and Mortality in Hemodialysis Patients: Marginal Structural Model to Examine Causality

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
It has been previously reported that a higher erythropoiesis stimulating agent (ESA) dose in hemodialysis patients is associated with adverse outcomes including mortality; however the causal relationship between ESA and mortality is still hotly debated. We hypothesize ESA dose indeed exhibits a direct linear relationship with mortality in models of association implementing the use of… Continue reading Erythropoietin Dose and Mortality in Hemodialysis Patients: Marginal Structural Model to Examine Causality

Statistical Analysis of Relationship between Daytime Lidar-Derived Planetary Boundary Layer Height and Relevant Atmospheric Variables in the Semiarid Region in Northwest China

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Accurate identification of key parameters for data assimilation is important in simulating the planetary boundary layer height (PBLH) and structure evolution in numerical weather prediction models. In this study, surface observational data and lidar-derived PBLH on 42 cloudless days from June 2007 to May 2008 are used to quantify the statistical relationships between surface parameters… Continue reading Statistical Analysis of Relationship between Daytime Lidar-Derived Planetary Boundary Layer Height and Relevant Atmospheric Variables in the Semiarid Region in Northwest China

Self-Shrinkage Behaviors of Waste Paper Fiber Reinforced Cement Paste considering Its Self-Curing Effect at Early-Ages

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
The aim of this paper was to study how the early-age self-shrinkage behavior of cement paste is affected by the addition of the waste paper fibers under sealed conditions. Although the primary focus was to determine whether the waste paper fibers are suitable to mitigate self-shrinkage as an internal curing agent under different adding ways,… Continue reading Self-Shrinkage Behaviors of Waste Paper Fiber Reinforced Cement Paste considering Its Self-Curing Effect at Early-Ages

GSE74845 Epigenetic reprogramming of Fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Contributor : Martin Widschwendter Series Type : Methylation profiling by genome tiling array Organism : Homo sapiens The development of non-invasive primary cancer preventive measures in humans require a thorough understanding of the initial cancer-driving molecular mechanisms. High grade serous extra-uterine M llerian cancers (HGSEMC; formerly classified as ovarian/tubal/peritoneal cancer) present at a very late… Continue reading GSE74845 Epigenetic reprogramming of Fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution

A New Technique for Posterior Distraction in Craniosynostosis: The Double-Door Technique.

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Background: Posterior cranial vault distraction osteogenesis is a common treatment for syndromal patients of brachycephaly and oxycephaly. Although posterior distraction can increase intracranial volume, the flattened head phenotype is difficult to correct. The authors examined a new posterior distraction technique termed double-door distraction for improvement of the flattened head phenotype. Methods: From 2010 to 2013,… Continue reading A New Technique for Posterior Distraction in Craniosynostosis: The Double-Door Technique.

Survival Without Neurological Impairment of a Patient With Rhino-Orbito-Cerebral Zygomycosis.

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Rhinocerebral zygomycosis is a rare condition characterized by infection initially in the nose and paranasal sinuses with atypical symptoms consistent with sinusitis. Once established in the nasal sinuses, the infection can easily spread to the orbital region and brain. In the localized form of the infection, the mortality rate is approximately 10%, which increases in… Continue reading Survival Without Neurological Impairment of a Patient With Rhino-Orbito-Cerebral Zygomycosis.

The Retromolar Trigone: Anatomy, Cancer Treatment Modalities, Reconstruction, and a Classification System.

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Background: Retromolar trigone (RMT) tumors are rare and aggressive malignancies, spreading rapidly into surrounding structures. In reviewing the literature, there is lack of information and quality evidence pertaining to their management and high heterogeneity in treatment modalities. Methods: A systematic Medline search was performed to gather all reports of articles related to retromolar trigone in… Continue reading The Retromolar Trigone: Anatomy, Cancer Treatment Modalities, Reconstruction, and a Classification System.

Delayed Onset Intracranial Subdural Hematoma Following Spinal Surgery.

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
In this case-based review, the authors analyzed relevant literature with an illustrative patient of theirs about subdural hematoma secondary to dural tear at spinal surgery. Intracranial hypotension is a condition of decreased cerebrospinal fluid volume and pressure. Even though intracranial hypotension is temporary and can be managed conservatively, it may progress and result in subdural… Continue reading Delayed Onset Intracranial Subdural Hematoma Following Spinal Surgery.

A Case of Aspiration Pneumonia After Mandibular Osteotomy With Genioplasty.

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Orthognathic surgery including maxillary osteotomy, mandibular osteotomy, and genioplasty is a reliable treatment strategy for jaw deformity. However, there are some complications associated with these surgeries, including neurovascular damage and abnormal bleeding. The authors present here a patient of aspiration pneumonia after mandibular osteotomy. An 18-year-old female patient underwent sagittal split ramus osteotomy and genioplasty… Continue reading A Case of Aspiration Pneumonia After Mandibular Osteotomy With Genioplasty.

Considerations for Management of Head and Neck Lymphatic Malformations in Children.

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Objective: There exist inherent problems with previously described classification schemes for head and neck lymphatic malformations in children and lack of guidance for management. An organization scheme and management recommendations are proposed to improve communication between health care providers. Study Design: Consecutive patient series with a chart review of children with head and neck lymphatic… Continue reading Considerations for Management of Head and Neck Lymphatic Malformations in Children.

A Phoneme Perception Test Method for High-Frequency Hearing Aid Fitting

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 2 ώρες
from #Audiology via xlomafota13 on Inoreader http://ift.tt/209uAV1 via IFTTT

The Effect of the Arabic Computer Rehabilitation Program “Rannan” on Sound Detection and Discrimination in Children with Cochlear Implants

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 2 ώρες
from #Audiology via xlomafota13 on Inoreader http://ift.tt/1VaG0IW via IFTTT

Recognition of Speech from the Television with Use of a Wireless Technology Designed for Cochlear Implants

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 2 ώρες
from #Audiology via xlomafota13 on Inoreader http://ift.tt/209uFIh via IFTTT

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