Head and Neck Medicine by Alexandros G.Sfakianakis: OtoRhinoLaryngology & Medicine,New Articles,May 6th,2016,a

Παρασκευή 6 Μαΐου 2016

OtoRhinoLaryngology & Medicine,New Articles,May 6th,2016,a

Paraprosthetic Erosion of the Ileum after an Aorto-femoral Bypass

Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 27 δευτερόλεπτα

Publication date: Available online 6 May 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): F. Famá, R. Gaeta from Endocrinology via ola Kala on Inoreader http://ift.tt/21DB4wW via IFTTT

Walking Capacity Is Positively Related with Heart Rate Variability in Symptomatic Peripheral Artery Disease

Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 27 δευτερόλεπτα

Publication date: Available online 6 May 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): A.H.R.A. Lima, A.H.G. Soares, G.G. Cucato, A.S. Leicht, F.G.M. Franco, N. Wolosker, R.M. Ritti-Dias ObjectivesThe aim was to investigate the association between walking capacity and HRV in patients with symptomatic peripheral artery disease (PAD).MethodsThis was a cross sectional study. Ninety-five patients were recruited. Patients undertook a supine position for 20 minutes, with the final 10 minutes used to examine for resting HRV. Time domain, frequency domain, a...περισσότερα »

Iliac Artery Endofibrosis

Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 27 δευτερόλεπτα

Publication date: Available online 6 May 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): R.J. Hinchliffe from Endocrinology via ola Kala on Inoreader http://ift.tt/21DB3c7 via IFTTT

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 5 δευτερόλεπτα

*Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.* Am J Respir Cell Mol Biol. 2016 May 5; Authors: Jude J, Koziol-White C, Scala J, Yoo E, Jester W, Maute C, Dalton P, Panettieri R Abstract BACKGROUND: Formaldehyde, a common indoor air pollutant, exacerbates asthma and synergizes with allergen to induce airway hyperresponsiveness (AHR) in animal models. The mechanisms mediating formaldehyde-induced AHR remain poorly understood. We posit that formaldehyde modulates agonist-induced contractile response of human airway smooth muscle (HASM) cel... περισσότερα »

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 6 δευτερόλεπτα

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 6 δευτερόλεπτα

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 6 δευτερόλεπτα

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 6 δευτερόλεπτα

Adverse Reaction to Cetuximab, an Epidermal Growth Factor Receptor Inhibitor.

Alexandros G. SfakianakisστοHead and NeckΠριν από 9 δευτερόλεπτα

*Adverse Reaction to Cetuximab, an Epidermal Growth Factor Receptor Inhibitor.* Acta Dermatovenerol Croat. 2016 Apr;24(1):70-72 Authors: Štulhofer Buzina D, Martinac I, Ledić Drvar D, Čeović R, Bilić I, Marinović B Abstract Dear Editor, Inhibition of the epidermal growth factor receptor (EGFR) is a new strategy in treatment of a variety of solid tumors, such as colorectal carcinoma, non-small cell lung cancer, squamous cell carcinoma of the head and neck, and pancreatic cancer (1). Cetuximab is a chimeric human-murine monoclonal antibody against EGFR. Cutaneous side effects are t...περισσότερα »

Diagnostic whole body scan (pre-therapy scan) in differentiated thyroid cancer: A single center community hospital experience.

Alexandros G. SfakianakisστοHead and NeckΠριν από 9 δευτερόλεπτα

*Diagnostic whole body scan (pre-therapy scan) in differentiated thyroid cancer: A single center community hospital experience.* Indian J Cancer. 2016 Jan-Mar;53(1):178-80 Authors: Santhanam P, Driscoll HK, Venkatraman P Abstract OBJECTIVE: Diagnostic whole body scan (pre-therapy scan) with either I-123 or I-131 (radioactive isotopes of iodine) is performed to assess the extent of thyroid cancer especially distant metastasis prior to administering the therapeutic dose of I-131. Our aim of the following study was to determine the utility of the diagnostic pre-therapy scan in the ma... περισσότερα »

Upper Respiratory Tract Infections

Alexandros G. SfakianakisστοHead and NeckΠριν από 9 δευτερόλεπτα

48 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2016/05/06 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1STyNb8 via IFTTT

ABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugs.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα

[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *ABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugs.* PLoS One. 2015;10(6):e0131038 Authors: Nicoletti P, Bansal M, Lefebvre C, Guarnieri P, Shen Y, Pe'er I, Califano A, Floratos A Abstract Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) represent rare but serious adverse drug reactions (ADRs). Both are characterized by distinctive blistering lesions and signific... περισσότερα »

Unusual Eruptions Associated with Mycoplasma pneumoniae Respiratory Infections: Review of the Literature.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα

[image: http:--misc.karger.com-LinkOutIcons-sk_n] Related Articles *Unusual Eruptions Associated with Mycoplasma pneumoniae Respiratory Infections: Review of the Literature.* Dermatology. 2015;231(2):152-7 Authors: Terraneo L, Lava SA, Camozzi P, Zgraggen L, Simonetti GD, Bianchetti MG, Milani GP Abstract BACKGROUND: Maculopapular or urticarial eruptions and erythema multiforme sometimes occur in patients affected with Mycoplasma pneumoniae respiratory infections. Further eruptions have also been reported. OBJECTIVE: To review the literature addressing M. pneumoniae respiratory i... περισσότερα »

Comparison of Patient- and Practitioner-Reported Toxic Effects Associated With Chemoradiotherapy for Head and Neck Cancer.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα

*Comparison of Patient- and Practitioner-Reported Toxic Effects Associated With Chemoradiotherapy for Head and Neck Cancer.* JAMA Otolaryngol Head Neck Surg. 2016 May 5; Authors: Falchook AD, Green R, Knowles ME, Amdur RJ, Mendenhall W, Hayes DN, Grilley-Olson JE, Weiss J, Reeve BB, Mitchell SA, Basch EM, Chera BS Abstract Importance: Agreement between patient- and practitioner-reported toxic effects during chemoradiotherapy for head and neck cancer is unknown. Objective: To compare patient-reported symptom severity and practitioner-reported toxic effects among patients receiving ... περισσότερα »

Comparison of Conventional, Revascularized, and Bioengineered Methods of Recurrent Laryngeal Nerve Reconstruction.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα

*Comparison of Conventional, Revascularized, and Bioengineered Methods of Recurrent Laryngeal Nerve Reconstruction.* JAMA Otolaryngol Head Neck Surg. 2016 May 5; Authors: Sand JP, Park AM, Bhatt N, Desai SC, Marquardt L, Sakiyama-Elbert S, Paniello RC Abstract Importance: Damage to the recurrent laryngeal nerve (RLN) is highly detrimental to voice, swallow, and cough. The optimal method for reconstitution of a nerve gap after injury is unknown. Objective: To evaluate multiple methods of RLN reconstruction. Design, Setting, and Participants: This study used an established canine mo...περισσότερα »

Effect of Basic Fibroblast Growth Factor in Tympanic Membrane Perforation.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα

*Effect of Basic Fibroblast Growth Factor in Tympanic Membrane Perforation.* JAMA Otolaryngol Head Neck Surg. 2016 May 5; Authors: Lou Z, Fu Y PMID: 27149323 [PubMed - as supplied by publisher] from #ORL via xlomafota13 on Inoreader http://ift.tt/1WdLyDV via IFTTT

Patient-Reported Toxic Effects-The Dawn of a New Era.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα

*Patient-Reported Toxic Effects-The Dawn of a New Era.* JAMA Otolaryngol Head Neck Surg. 2016 May 5; Authors: Worden FP PMID: 27149196 [PubMed - as supplied by publisher] from #ORL via xlomafota13 on Inoreader http://ift.tt/1OgFJwX via IFTTT

Painless, Nonhealing Submental Ulcer.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα

*Painless, Nonhealing Submental Ulcer.* JAMA Otolaryngol Head Neck Surg. 2016 May 5; Authors: O'Toole TR, Ghai R, Nielsen T PMID: 27149053 [PubMed - as supplied by publisher] from #ORL via xlomafota13 on Inoreader http://ift.tt/1WdLvrJ via IFTTT

Further delineation of FKBP14-related Ehlers-Danlos syndrome: A patient with early vascular complications and non-progressive kyphoscoliosis, and literature review.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 12 δευτερόλεπτα

*Further delineation of FKBP14-related Ehlers-Danlos syndrome: A patient with early vascular complications and non-progressive kyphoscoliosis, and literature review.* Am J Med Genet A. 2016 May 5; Authors: Dordoni C, Ciaccio C, Venturini M, Calzavara-Pinton P, Ritelli M, Colombi M Abstract FKBP14-related Ehlers-Danlos syndrome (EDS) is an extremely rare recessive connective tissue disorder described for the first time in 2012 by Baumann and coworkers. The causal gene, FKBP14, encodes a member of the F506-binding family of peptidyl-prolyl cis-trans isomerases. The paucity of pati... περισσότερα »

Child abuse and fabricated or induced illness in the ENT setting: a systematic review.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 12 δευτερόλεπτα

*Child abuse and fabricated or induced illness in the ENT setting: a systematic review.* Clin Otolaryngol. 2016 May 5; Authors: Rees P, Al-Hussaini A, Maguire S Abstract BACKGROUND: Child maltreatment is persistently under-recognised. Given that a third of maltreated children may return with serious or fatal injuries, it is imperative that otolaryngologists who are in frequent contact with children are able to detect maltreatment at first presentation. OBJECTIVE OF REVIEW: This review aims to identify ENT injuries, signs or symptoms that are indicative of physical abuse or fabrica... περισσότερα »

Salivary FOXP2 expression and oral feeding success in premature infants.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

*Salivary FOXP2 expression and oral feeding success in premature infants.* Cold Spring Harb Mol Case Stud. 2016 Jan;2(1):a000554 Authors: Zimmerman E, Maki M, Maron J Abstract The objective of the study is to determine whether salivary FOXP2 gene expression levels at the initiation of oral feeding attempts are predictive of oral feeding success in the premature newborn. In this prospective study, saliva samples from 21 premature infants (13 males; birth gestational age [GA]: 30-34 wk) were collected around the initiation of oral feeding trials. Total RNA was extracted and underwen...περισσότερα »

Valproate ameliorates nitroglycerin-induced migraine in trigeminal nucleus caudalis in rats through inhibition of NF-кB

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

As a complex nervous system disease, migraine causes severe healthy and social issues worldwide. Valproate (VPA) is a widely used treatment agent against seizures and bipolar disorder, and its function to alle... from #ENT via xlomafota13 on Inoreader http://ift.tt/1WcjJv1 via IFTTT

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

[Transthoracic myotomy of a case of giant megaesophagus in Mali hospital].

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

[image: http:--http://ift.tt/1MOzwGw] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *[Transthoracic myotomy of a case of giant megaesophagus in Mali hospital].* Pan Afr Med J. 2015;21:239 Authors: Togo S, Abdoulaye OM, Xing L, Sadio Y PMID: 26523179 [PubMed - indexed for MEDLINE] from #ENT via xlomafota13 on Inoreader http://ift.tt/1rxUNBM via IFTTT

Randomised clinical trial: transoral incisionless fundoplication vs. sham intervention to control chronic GERD.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Randomised clinical trial: transoral incisionless fundoplication vs. sham intervention to control chronic GERD.* Aliment Pharmacol Ther. 2015 Dec;42(11-12):1261-70 Authors: Håkansson B, Montgomery M, Cadiere GB, Rajan A, Bruley des Varannes S, Lerhun M, Coron E, Tack J, Bischops R, Thorell A, Arnelo U, Lundell L Abstract BACKGROUND: Until recently only two therapeutic options have been available to control symptoms and the esophagitis in chronic gastro-oesophageal reflux disease (GERD), i.e. lifelong proton pump ... περισσότερα »

Oesophageal signet ring cell carcinoma as complication of gastro-oesophageal reflux disease.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Oesophageal signet ring cell carcinoma as complication of gastro-oesophageal reflux disease.* Aliment Pharmacol Ther. 2015 Nov;42(10):1222-31 Authors: Turner KO, Genta RM, Sonnenberg A Abstract BACKGROUND: Signet ring cell carcinoma occurs as a histological variant of oesophageal adenocarcinoma. AIM: In a cross-sectional study, to pursue the hypothesis that oesophageal signet ring cell cancers constitute a complication of gastro-oesophageal reflux disease. METHODS: In a large national database of histopathology re... περισσότερα »

Delayed hypersensitivity reaction after cervical disc replacement: a case report.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Delayed hypersensitivity reaction after cervical disc replacement: a case report.* Orthop Traumatol Surg Res. 2015 Sep;101(5):643-5 Authors: Lagier M, Briere M, Giorgi H, Fuentes S, Blondel B, Tropiano P Abstract We report a case of allergic reaction after total cervical disc arthroplasty. A 52-year old woman was operated on for right C6 cervicobrachial neuralgia secondary to C5-C6 disc disease with foraminal stenosis. A cobalt-chromium-molybdenum total disc prosthesis had been implanted two years earlier. The pa... περισσότερα »

Gastroesophageal reflux and lung disease.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Related Articles *Gastroesophageal reflux and lung disease.* Expert Rev Respir Med. 2015 Aug;9(4):383-5 Authors: Meyer KC Abstract Gastroesophageal reflux (GER) can cause respiratory symptoms and may trigger, drive and/or worsen airway disorders, interstitial lung diseases and lung allograft dysfunction. Whether lifestyle changes and acid suppression alone can counter and prevent the adverse effects of GER on the respiratory tract remains unclear. Recent data suggest that antireflux surgery may be more effective in preventing lung disease progression in patients with idiopathic ... περισσότερα »

Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

[image: http:--http://ift.tt/1SvbKVd] Related Articles *Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study.* Endoscopy. 2015 Aug;47(8):669-74 Authors: Sinh P, Anaparthy R, Young PE, Gaddam S, Thota P, Balasubramanian G, Singh M, Higbee AD, Wani S, Gupta N, Rastogi A, Mathur SC, Bansal A, Horwhat JD, Cash BD, Falk GW, Lieberman DA, Vargo JJ, Sampliner RE, Sharma P Abstract BACKGROUND AND STUDY AIM: Data are limited on the natural history of patients with Barrett's esophagus with a diagnosis of "indefinite ... περισσότερα »

More art than science: impedance analysis prone to interpretation error.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

[image: http:--production.springer.de-OnlineReso] Related Articles *More art than science: impedance analysis prone to interpretation error.* J Gastrointest Surg. 2015 Jun;19(6):987-92 Authors: Ciecierega T, Gordon BL, Aronova A, Crawford CV, Zarnegar R Abstract BACKGROUND: Impedance monitoring for reflux evaluation does not have standardized scoring, which can confound interpretation between observers. We investigated the variability of impedance testing interpretation between physicians and computer software. METHODS: Raw impedance data from 38 patients that underwent impedance ... περισσότερα »

Perspectives on the role of the speech and language therapist in palliative care: An international survey.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Related Articles *Perspectives on the role of the speech and language therapist in palliative care: An international survey.* Palliat Med. 2015 Sep;29(8):756-61 Authors: O'Reilly AC, Walshe M Abstract BACKGROUND: Speech and language therapists can improve the quality of life of people receiving palliative care through the management of communication and swallowing difficulties (dysphagia). However, their role in this domain is poorly defined and little is understood about the current international professional practice in this field. AIMS: To examine how speech and language thera... περισσότερα »

Galectin-1 is essential for the induction of MOG35-55-based intravenous tolerance in experimental autoimmune encephalomyelitis

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

[image: cover.gif?v=1&s=b21358abd3cdaaa7c9eaac8d] In experimental autoimmune encephalomyelitis (EAE), intravenous (i.v.) injection of the antigen, myelin oligodendrocyte glycoprotein-derived peptide, MOG35-55, suppresses disease development, a phenomenon called i.v. tolerance. Galectin-1, an endogenous glycan-binding protein, is upregulated during autoimmune neuroinflammation and plays immunoregulatory roles by inducing tolerogenic dendritic cells (DCs) and IL-10-producing regulatory type 1 T (Tr1) cells. To examine the role of galectin-1 in i.v. tolerance, we administered MOG35-5... περισσότερα »

Key roles of autophagy in regulating T-cell function

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Abstract In the past 10 years, autophagy has emerged as a crucial regulator of T-cell homeostasis, activation and differentiation. Through the ability to adjust the cell's proteome in response to different stimuli, different forms of autophagy have been shown to control T-cell homeostasis and survival. Autophagic processes can also determine the magnitude of the T-cell response to TCR engagement, by regulating the cellular levels of specific signaling intermediates and modulating the metabolic output in activated T cells. In this review we will examine the mechanisms that control ... περισσότερα »

Activation of murine invariant NKT cells promotes susceptibility to candidiasis by IL-10-induced modulation of phagocyte antifungal activity

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

[image: cover.gif?v=1&s=b21358abd3cdaaa7c9eaac8d] Invariant NKT (iNKT) cells play an important role in a variety of antimicrobial immune responses due to their ability to produce high levels of immunemodulating cytokines. Here, we investigated the role of iNKT cells in host defense against candidiasis using *Jα18*-deficient mice (*Jα18*−/−), which lack iNKT cells. *Jα18*−/- mice were more resistant to the development of lethal candidiasis than wild-type (WT) mice. In contrast, treatment of WT mice with the iNKT cell activating ligand α-galactosylceramide markedly enhanced their mo...περισσότερα »

Cell origin in the macula flava of the human newborn vocal fold

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Research Articles K Sato, S Chitose, T Kurita, H Umeno The Journal of Laryngology & Otology,FirstView Article(s), 6 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #ENT via xlomafota13 on Inoreader http://ift.tt/1O2eGuu via IFTTT

Development of an item bank for the EORTC Role Functioning Computer Adaptive Test (EORTC RF-CAT)

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα

Role functioning (RF) as a core construct of health-related quality of life (HRQOL) comprises aspects of occupational and social roles relevant for patients in all treatment phases as well as for survivors. Th… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1rZKkj0 via IFTTT

Osterix and RUNX2 are Transcriptional Regulators of Sclerostin in Human Bone

Abstract Sclerostin, encoded by the SOST gene, works as an inhibitor of the Wnt pathway and therefore is an important regulator of bone homeostasis. Due to its potent action as an inhibitor of bone formation, blocking sclerostin activity is the purpose of recently developed anti-osteoporotic treatments. Two bone-specific transcription factors, RUNX2 and OSX, have been […]

Health Technology

216 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: health technology These pubmed results were generated on 2016/05/06 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content […]

Antibiotics, Vol. 5, Pages 15: Antibiotics and RNase P

RNase P is an essential endonuclease in tRNA biogenesis, which generates the mature 5′-termini of tRNAs. Most forms of RNase P are ribonucleoproteins, i.e., they consist of an essential RNA and protein subunits. The catalytic function of ribonucleoprotein RNase P enzymes resides entirely in the RNA subunit. Its high structural and functional diversity among representatives […]

A Radiomics Nomogram for Preoperative Prediction of Lymph Node Metastasis

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 14 δευτερόλεπτα

Development and Validation of a Radiomics Nomogram for Preoperative Prediction of Lymph Node Metastasis in Colorectal Cancer [Gastrointestinal Cancer]: Purpose To develop and validate a radiomics nomogram for preoperative prediction of lymph node (LN) metastasis in patients with colorectal cancer (CRC). Patients and Methods The prediction model was developed in a primary cohort that consisted of 326 patients with clinicopathologically confirmed CRC, and data was gathered from January 2007 to April 2010. Radiomic features were extracted from portal venous–phase computed tomography (... περισσότερα »

Child abuse and fabricated or induced illness in the ENT setting: a systematic review.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 14 δευτερόλεπτα

Salivary FOXP2 expression and oral feeding success in premature infants.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 14 δευτερόλεπτα

FOXP2 gene deletion and infant feeding difficulties: a case report.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 14 δευτερόλεπτα

*FOXP2 gene deletion and infant feeding difficulties: a case report.* Cold Spring Harb Mol Case Stud. 2016 Jan;2(1):a000547 Authors: Zimmerman E, Maron JL Abstract Forkhead box protein P2 (FOXP2) is a well-studied gene known to play an essential role in normal speech development. Deletions in the gene have been shown to result in developmental speech disorders and regulatory disruption of downstream gene targets associated with common forms of language impairments. Despite similarities in motor planning and execution between speech development and oral feeding competence, there ha... περισσότερα »

Gastroscopic removal of a giant fibrovascular polyp from the esophagus.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 14 δευτερόλεπτα

*Gastroscopic removal of a giant fibrovascular polyp from the esophagus.* Thorac Cancer. 2016 Apr 26;7(3):363-6 Authors: Li J, Yu H, Pu R, Lu Z Abstract Giant polyps in the esophagus are rarely occurring benign tumors and may contain lipomas, fibrovascular polyps, fibrolipomas or neurofibromas polyps. Clinical symptoms include dysphagia, vomiting, retrosternal pain, shortness of breath, and asthma. In some cases, the polyps are regurgitated into the oral cavity and represent a spectacular manifestation. The reported case in this study was of a 50-year-old man who complained of em... περισσότερα »

Clinical features and prognosis in anti-SRP and anti-HMGCR necrotising myopathy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 14 δευτερόλεπτα

*Clinical features and prognosis in anti-SRP and anti-HMGCR necrotising myopathy.* J Neurol Neurosurg Psychiatry. 2016 May 4; Authors: Watanabe Y, Uruha A, Suzuki S, Nakahara J, Hamanaka K, Takayama K, Suzuki N, Nishino I Abstract OBJECTIVE: To elucidate the common and distinct clinical features of immune-mediated necrotising myopathy (IMNM), also known as necrotising autoimmune myopathy associated with autoantibodies against signal recognition particle (SRP) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR). METHODS: We examined a cohort of 460 patients with idiopathic... περισσότερα »

A Preliminary Study of How the Viscosity of Dietary Fluids and Videofluoroscopy Fluids can be Matched.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 14 δευτερόλεπτα

*A Preliminary Study of How the Viscosity of Dietary Fluids and Videofluoroscopy Fluids can be Matched.* Dysphagia. 2016 May 5; Authors: Suzuki H, Kondo I, Sakamoto K, Kimura K, Matsumoto T Abstract This study examined the method by which the viscosity of mealtime and videofluoroscopy fluid can be matched through adjustment of the amount of xanthan gum-based thickener added to them. Viscosity measurement was made with a cone-plate viscometer. Samples were tested at 5, 25, 45, and 65 ± 0.1 °C and shear rates of 5-200 s(-1). We found that the adjusted amount of thickener differs de...περισσότερα »

[Transthoracic myotomy of a case of giant megaesophagus in Mali hospital].

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 14 δευτερόλεπτα

[image: http:--http://ift.tt/1MOzwGw] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *[Transthoracic myotomy of a case of giant megaesophagus in Mali hospital].* Pan Afr Med J. 2015;21:239 Authors: Togo S, Abdoulaye OM, Xing L, Sadio Y PMID: 26523179 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1rxUNBM via IFTTT

Randomised clinical trial: transoral incisionless fundoplication vs. sham intervention to control chronic GERD.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 14 δευτερόλεπτα

Delayed hypersensitivity reaction after cervical disc replacement: a case report.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 14 δευτερόλεπτα

The Causal Relationship Between Income and Health

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Invited Commentary: Using Financial Credits as Instrumental Variables for Estimating the Causal Relationship Between Income and Health: Social epidemiologists are interested in determining the causal relationship between income and health. Natural experiments in which individuals or groups receive income randomly or quasi-randomly from financial credits (e.g., tax credits or cash transfers) are increasingly being analyzed using instrumental variable analysis. For example, in this issue of the *Journal*, Hamad and Rehkopf (*Am J Epidemiol*. 2016;183(9):775–784) used an in-work tax c... περισσότερα »

Poverty and Child Development

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

A Longitudinal Study of the Impact of the Earned Income Tax Credit: Although adverse socioeconomic conditions are correlated with worse child health and development, the effects of poverty-alleviation policies are less understood. We examined the associations of the Earned Income Tax Credit (EITC) on child development and used an instrumental variable approach to estimate the potential impacts of income. We used data from the US National Longitudinal Survey of Youth (*n* = 8,186) during 1986–2000 to examine effects on the Behavioral Problems Index (BPI) and Home Observation Measur...περισσότερα »

History of Severe Sunburn and Risk of Skin Cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Among Women and Men in 2 Prospective Cohort Studies: Few studies have assessed the relationship between sunburn and risk of different skin cancers (melanoma, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC)) in prospective studies simultaneously, and little is known about the association of severe sunburns at different body sites with skin cancer risk. We used data on 87,166 women in the Nurses' Health Study (1982–2010) and 32,959 men in the Health Professionals Follow-up Study (1992–2010) to investigate skin cancer risk associated with history of severe sunburns at d...περισσότερα »

Incident Ischemic Heart Disease After Long-Term Occupational Exposure to Fine Particulate Matter

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Accounting for 2 Forms of Survivor Bias: Little is known about the heart disease risks associated with occupational, rather than traffic-related, exposure to particulate matter with aerodynamic diameter of 2.5 µm or less (PM2.5). We examined long-term exposure to PM2.5 in cohorts of aluminum smelters and fabrication workers in the United States who were followed for incident ischemic heart disease from 1998 to 2012, and we addressed 2 forms of survivor bias. Left truncation bias was addressed by restricting analyses to the subcohort hired after the start of follow up. Healthy work... περισσότερα »

Statins for Breast Cancer Prevention

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Statins for Breast Cancer Prevention: Statins have the potential to reduce breast cancer incidence and recurrence as shown in both epidemiologic and laboratory studies. The purpose of this study was to evaluate the effect of a lipophilic statin, atorvastatin, on breast cancer biomarkers of risk [mammographic density (MD) and insulin growth factor 1 (IGF-1)] in high-risk premenopausal women. Premenopausal women at increased risk for breast cancer received either 40 mg of atorvastatin or placebo for 1 year. Biomarker assessment was performed prior to initiation and at completion of s... περισσότερα »

The tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Clinical Trial of 2-Phenethyl Isothiocyanate: 2-Phenethyl isothiocyanate (PEITC), a natural product found as a conjugate in watercress and other cruciferous vegetables, is an inhibitor of the metabolic activation and lung carcinogenicity of the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in F344 rats and A/J mice. We carried out a clinical trial to determine whether PEITC also inhibits the metabolic activation of NNK in smokers. Cigarette smokers were recruited and asked to smoke cigarettes containing deuterium-labeled [pyridine-D4]NNK for an acclimation... περισσότερα »

Neuromuscular electrical stimulation improves radiation-induced fibrosis through Tgf-Β1/MyoD homeostasis in head and neck cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Neuromuscular electrical stimulation improves radiation-induced fibrosis through Tgf-Β1/MyoD homeostasis in head and neck cancer: Objectives The purpose of this study was to analyze TGF-β1 and MyoD expression in cervical muscles during radiation therapy (RT) and their role in inducing muscle fibrosis in head and neck cancer (HNC) patients. We also studied the effect of combined traditional swallow therapy (TST) and neuromuscular electrical stimulation (NMES) therapy on TGF-β1/MyoD homeostasis in patients undergoing post-operative RT for HNC. Study Design Case–control study. Methods ...περισσότερα »

Enobosarm, a Selective Androgen Receptor Modulator, for the Prevention and Treatment of Muscle Wasting in Cancer Patients (POWER Trials)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Study Design and Rationale for the Phase 3 Clinical Development Program of Enobosarm, a Selective Androgen Receptor Modulator, for the Prevention and Treatment of Muscle Wasting in Cancer Patients (POWER Trials): AbstractMuscle wasting in cancer is a common and often occult condition that can occur prior to overt signs of weight loss and before a clinical diagnosis of cachexia can be made. Muscle wasting in cancer is an important and independent predictor of progressive functional impairment, decreased quality of life, and increased mortality. Although several therapeutic agents ar... περισσότερα »

Immunohistochemical Study EMT-Related Proteins in HPV-, and EBV-Negative Patients with Sinonasal Tumours

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Immunohistochemical Study EMT-Related Proteins in HPV-, and EBV-Negative Patients with Sinonasal Tumours: AbstractEpithelial to mesenchymal transition (EMT) is a biological process in which the epithelial cells, transform to mesenchymal cells via multiple biochemical modifications. Immunohistochemical method was used to examine the expression of EMT-related proteins: Slug, E-cadherin and fibronectin, in 41 cases of sinonasal inverted papilloma (SIP), 33 cases of sinonasal squamous cell carcinoma (SNC), and 22 cases of normal mucosa as a control. In all cases negative viral status w... περισσότερα »

Lead identification for the K-Ras protein

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Lead identification for the K-Ras protein: Akbar Ali Khan Pathan,1,2,* Bhavana Panthi,3,* Zahid Khan,1 Purushotham Reddy Koppula,4–6Mohammed Saud Alanazi,1 Sachchidanand,3 Narasimha Reddy Parine,1 Mukesh Chourasia3,* 1Genome Research Chair (GRC), Department of Biochemistry, College of Science, King Saud University, 2Integrated Gulf Biosystems, Riyadh, Kingdom of Saudi Arabia; 3Department of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research, Hajipur, India;4Department of Internal Medicine, School of Medicine, 5Harry S. Truman Memorial Veterans Affairs... περισσότερα »

LDL-C levels and prognosis in nasopharyngeal carcinoma patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

LDL-C levels and prognosis in nasopharyngeal carcinoma patients: Qiu Tang, Qiao-Ying Hu, Yong-feng Piao, Yong-Hong Hua Department of Head and Neck Cancer Radiotherapy, Zhejiang Cancer Hospital, Hangzhou, Zhejiang, People’s Republic of China *Purpose: *To investigate the correlations between long-term survival outcomes in patients with nasopharyngeal carcinoma (NPC) and pretreatment serum low-density lipoprotein cholesterol (LDL-C) levels. *Patients and methods: *Between January 2008 and December 2011, 935 patients with newly diagnosed NPC who were treated with intensity-modulated ... περισσότερα »

Drinking Water and Arsenic

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Elevated Bladder Cancer in Northern New England: The Role of Drinking Water and Arsenic: *Background:* Bladder cancer mortality rates have been elevated in northern New England for at least five decades. Incidence rates in Maine, New Hampshire, and Vermont are about 20% higher than the United States overall. We explored reasons for this excess, focusing on arsenic in drinking water from private wells, which are particularly prevalent in the region. *Methods:* In a population-based case-control study in these three states, 1213 bladder cancer case patients and 1418 control subjects ...περισσότερα »

Strategies to genetically engineer T cells for cancer immunotherapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Strategies to genetically engineer T cells for cancer immunotherapy: AbstractImmunotherapy is one of the most promising and innovative approaches to treat cancer, viral infections, and other immune-modulated diseases. Adoptive immunotherapy using gene-modified T cells is an exciting and rapidly evolving field. Exploiting knowledge of basic T cell biology and immune cell receptor function has fostered innovative approaches to modify immune cell function. Highly translatable clinical technologies have been developed to redirect T cell specificity by introducing designed receptors. Th... περισσότερα »

Utility of 18F-FDG-PET/CT in patients suspected of paraneoplastic neurological syndrome

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

: importance of risk classification: Abstract PurposeTo assess the diagnostic impact of 18F-FDG-PET/CT in patients suspected of paraneoplastic neurological syndrome (PNS) based on our own pre-test risk classification (PRC). MethodsA multicenter retrospective longitudinal study was conducted from 2006 to 2014. We designed a seven-point scoring system using the clinical syndrome characteristics [classical (CS) and non-classical syndromes (NCS)] and its location (central, peripheral, in the neuromuscular junction or combined), onconeural antibodies and tumor markers. Patients were...περισσότερα »

The gastrointestinal microbiome in infectious complications during induction chemotherapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

for acute myeloid leukemia: BACKGROUND Despite increasing data on the impact of the microbiome on cancer, the dynamics and role of the microbiome in infection during therapy for acute myelogenous leukemia (AML) are unknown. Therefore, the authors sought to determine correlations between microbiome composition and infectious outcomes in patients with AML who were receiving induction chemotherapy (IC). METHODS Buccal and fecal specimens (478 samples) were collected twice weekly from 34 patients with AML who were undergoing IC. Oral and stool microbiomes were characterized by 16S rib... περισσότερα »

Patients with early-stage esophageal adenocarcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Treatment allocation in patients with early-stage esophageal adenocarcinoma: Prevalence and predictors of lymph node involvement: BACKGROUND In considering treatment allocation for patients with early esophageal adenocarcinoma, the incidence of lymph node metastasis is a critical determinant; however, this has not been well defined or stratified by the relevant clinical predictors of lymph node spread. METHODS Data from the Surveillance, Epidemiology, and End Results database of the National Cancer Institute were abstracted from 2004 to 2010 for patients with early-stage esophageal ...περισσότερα »

Central nervous system embryonal tumours

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα

Incidence and survival of children and young people with central nervous system embryonal tumours in the North of England, 1990–2013 via ScienceDirect Publication: European Journal of Cancer Publication date: July 2016 *Source:*European Journal of Cancer, Volume 61 Author(s): L. Fairley, S.V. Picton, R.J.Q. McNally, S. Bailey, M.G. McCabe, R.G. Feltbower BackgroundMedulloblastoma and primitive neuroectodermal tumours (PNET) are the most common central nervous system (CNS) embryonal tumours diagnosed in childhood. Survival outcomes are worse for children diagnosed with CNS PNET compared... περισσότερα »

[Causal factor: chronic cerebrospinal venous insufficiency?].

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*[Causal factor: chronic cerebrospinal venous insufficiency?].* Laryngorhinootologie. 2016 Jan;95(1):4-5 Authors: Westhofen M, Todt I PMID: 27148608 [PubMed - in process] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1UEhWxJ via IFTTT

Exploiting Genetic Interference for Antiviral Therapy.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*Exploiting Genetic Interference for Antiviral Therapy.* PLoS Genet. 2016 May;12(5):e1005986 Authors: Tanner EJ, Kirkegaard KA, Weinberger LS Abstract Rapidly evolving viruses are a major threat to human health. Such viruses are often highly pathogenic (e.g., influenza virus, HIV, Ebola virus) and routinely circumvent therapeutic intervention through mutational escape. Error-prone genome replication generates heterogeneous viral populations that rapidly adapt to new selection pressures, leading to resistance that emerges with treatment. However, population heterogeneity bears a co... περισσότερα »

Fatal disseminated varicella zoster infection following zoster vaccination in an immunocompromised patient.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*Fatal disseminated varicella zoster infection following zoster vaccination in an immunocompromised patient.* BMJ Case Rep. 2016;2016 Authors: Costa E, Buxton J, Brown J, Templeton KE, Breuer J, Johannessen I Abstract A 79-year-old man with chronic lymphocytic leukaemia presented with fever and a widespread vesicular rash on 19 November 2014. The patient had not been under immunosuppressive regime for 6 months. He had received a shingles vaccine on 14th October and developed flu-like symptoms after 2 weeks. Intravenous antimicrobial therapy including aciclovir was started. He rem...περισσότερα »

Choosing Wisely: Can past medical decisions impact the allocation of scarce ECMO resources?

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*Choosing Wisely: Can past medical decisions impact the allocation of scarce ECMO resources?* Acta Paediatr. 2016 May 4; Authors: Kukora S, Laventhal N Abstract On a cold night in January 2013, I checked my email and was surprised by the message: "Due to the H1N1 flu epidemic, we cannot support any further ECMO patients as we have reached the limit of our equipment and staffing." My thoughts went to the expectant mother upstairs, carrying a fetus with an anomaly whose only hope for survival was ECMO. I wondered how I would tell her that the life-support therapy her baby needed wo...περισσότερα »

Oseltamivir for influenza, from birth: no more useful than in adults.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

Related Articles *Oseltamivir for influenza, from birth: no more useful than in adults.* Prescrire Int. 2016 Feb;25(168):53 Authors: PMID: 27073818 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1YcyA6B via IFTTT

Oseltamivir: over 15 years of data retention and systematic stonewalling.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

Related Articles *Oseltamivir: over 15 years of data retention and systematic stonewalling.* Prescrire Int. 2016 Feb;25(168):55 Authors: PMID: 27042737 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1YcyxaR via IFTTT

Oseltamivir and influenza: still no robust data.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

Related Articles *Oseltamivir and influenza: still no robust data.* Prescrire Int. 2016 Feb;25(168):52-4 Authors: PMID: 27042736 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1Ycyxrn via IFTTT

Ebola virus disease control in West Africa: an ecological, one health approach.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

[image: http:--http://ift.tt/1MOzwGw] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Ebola virus disease control in West Africa: an ecological, one health approach.* Pan Afr Med J. 2015;21:6 Authors: Meseko CA, Egbetade AO, Fagbo S Abstract The 2013-2015 Ebola Virus Disease outbreak in West Africa had similar nuances with the 1976 outbreaks in Central Africa; both were caused by the Zaire Ebola Virus strain and originated from rural forested communities. The definitive reservoir host of Ebola virus still remains unknown till date. However, from ecological perspective, i... περισσότερα »

Leveraging social networking sites for disease surveillance and public sensing: the case of the 2013 avian influenza A(H7N9) outbreak in China.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Leveraging social networking sites for disease surveillance and public sensing: the case of the 2013 avian influenza A(H7N9) outbreak in China.* Western Pac Surveill Response J. 2015 Apr-Jun;6(2):66-72 Authors: Zhang EX, Yang Y, Di Shang R, Simons JJ, Quek BK, Yin XF, See W, Oh OS, Nandar KS, Ling VR, Chan PP, Wang Z, Goh RS, James L, Tey JS Abstract We conducted in-depth analysis on the use of a popular Chinese social networking and microblogging site, Sina Weibo, to monitor an avian influenza A(H7N9) outbreak in China and t... περισσότερα »

An Assessment of the Expected Cost-Effectiveness of Quadrivalent Influenza Vaccines in Ontario, Canada Using a Static Model.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *An Assessment of the Expected Cost-Effectiveness of Quadrivalent Influenza Vaccines in Ontario, Canada Using a Static Model.* PLoS One. 2015;10(7):e0133606 Authors: Chit A, Roiz J, Aballea S Abstract Ontario, Canada, immunizes against influenza using a trivalent inactivated influenza vaccine (IIV3) under a Universal Influenza Immunization Program (UIIP). The UIIP offers IIV3 free-of-charge to all Ontarians over 6 months of age. A newly approved quadrivalent inactivated influenza vaccine ... περισσότερα »

Design of non-pharmaceutical intervention strategies for pandemic influenza outbreaks.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Design of non-pharmaceutical intervention strategies for pandemic influenza outbreaks.* BMC Public Health. 2014;14:1328 Authors: Martinez DL, Das TK Abstract BACKGROUND: As seen during past pandemic influenza outbreaks, pharmaceutical interventions (PHIs) with vaccines and antivirals are the most effective methods of mitigation. However, availability of PHIs is unlikely to be adequate during the early stages of a pandemic. Hence, for early mitigation and possible containment, non-pharma... περισσότερα »

Pandemic influenza and health system resource gaps in Bali: an analysis through a resource transmission dynamics model.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

Related Articles *Pandemic influenza and health system resource gaps in Bali: an analysis through a resource transmission dynamics model.* Asia Pac J Public Health. 2015 Mar;27(2):NP713-33 Authors: Adisasmito W, Hunter BM, Krumkamp R, Latief K, Rudge JW, Hanvoravongchai P, Coker RJ Abstract The failure to contain pandemic influenza A(H1N1) 2009 in Mexico has shifted global attention from containment to mitigation. Limited surveillance and reporting have, however, prevented detailed assessment of mitigation during the pandemic, particularly in low- and middle-income countries. To...περισσότερα »

Chemicals, Nutrition, and Autism Spectrum Disorder: A Mini-Review.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*Chemicals, Nutrition, and Autism Spectrum Disorder: A Mini-Review.* Front Neurosci. 2016;10:174 Authors: Fujiwara T, Morisaki N, Honda Y, Sampei M, Tani Y Abstract The rapid increase of the prevalence of autism spectrum disorder (ASD) suggests that exposure to chemicals may impact the development of ASD. Therefore, we reviewed literature on the following chemicals, nutrient to investigate their association with ASD: (1) smoke/tobacco, (2) alcohol, (3) air pollution, (4) pesticides, (5) endocrine-disrupting chemicals, (6) heavy metals, (7) micronutrients, (8) fatty acid, and (9) p... περισσότερα »

Joint Multi-Fiber NODDI Parameter Estimation and Tractography Using the Unscented Information Filter.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*Joint Multi-Fiber NODDI Parameter Estimation and Tractography Using the Unscented Information Filter.* Front Neurosci. 2016;10:166 Authors: Reddy CP, Rathi Y Abstract Tracing white matter fiber bundles is an integral part of analyzing brain connectivity. An accurate estimate of the underlying tissue parameters is also paramount in several neuroscience applications. In this work, we propose to use a joint fiber model estimation and tractography algorithm that uses the NODDI (neurite orientation dispersion diffusion imaging) model to estimate fiber orientation dispersion consisten... περισσότερα »

Implications of the Dependence of Neuronal Activity on Neural Network States for the Design of Brain-Machine Interfaces.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*Implications of the Dependence of Neuronal Activity on Neural Network States for the Design of Brain-Machine Interfaces.* Front Neurosci. 2016;10:165 Authors: Panzeri S, Safaai H, De Feo V, Vato A Abstract Brain-machine interfaces (BMIs) can improve the quality of life of patients with sensory and motor disabilities by both decoding motor intentions expressed by neural activity, and by encoding artificially sensed information into patterns of neural activity elicited by causal interventions on the neural tissue. Yet, current BMIs can exchange relatively small amounts of informat... περισσότερα »

Commentary: Parkinson's Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*Commentary: Parkinson's Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein.* Front Neurosci. 2016;10:162 Authors: Olszewska DA, McCarthy A, Lynch T PMID: 27147954 [PubMed] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1YcysUJ via IFTTT

Commentary: Evaluation of Models of Parkinson's Disease.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*Commentary: Evaluation of Models of Parkinson's Disease.* Front Neurosci. 2016;10:161 Authors: Muñoz P, Paris I, Segura-Aguilar J PMID: 27147953 [PubMed] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1UEhKP6 via IFTTT

Corrigendum: Molecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical Development.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*Corrigendum: Molecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical Development.* Front Neurosci. 2016;10:160 Authors: Ohtaka-Maruyama C, Okado H Abstract [This corrects the article on p. 447 in vol. 9, PMID: 26733777.]. PMID: 27147952 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1YcyuM7 via IFTTT

Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.

Alexandros G. SfakianakisστοHead and NeckΠριν από 20 δευτερόλεπτα

*Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.* Front Neurosci. 2016;10:159 Authors: Napoli E, Ross-Inta C, Song G, Wong S, Hagerman R, Gane LW, Smilowitz JT, Tassone F, Giulivi C Abstract Fragile X premutation alleles have 55-200 CGG repeats in the 5' UTR of the FMR1 gene. Altered zinc (Zn) homeostasis has been reported in fibroblasts from >60 years old premutation carriers, in which Zn supplementation significantly restored Zn-dependent mitochondrial protein import/processing and functio...περισσότερα »

Comparison of Conventional, Revascularized, and Bioengineered Methods of Recurrent Laryngeal Nerve Reconstruction.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 23 δευτερόλεπτα

Sensory Substitution: The Spatial Updating of Auditory Scenes "Mimics" the Spatial Updating of Visual Scenes.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 23 δευτερόλεπτα

*Sensory Substitution: The Spatial Updating of Auditory Scenes "Mimics" the Spatial Updating of Visual Scenes.* Front Behav Neurosci. 2016;10:79 Authors: Pasqualotto A, Esenkaya T Abstract Visual-to-auditory sensory substitution is used to convey visual information through audition, and it was initially created to compensate for blindness; it consists of software converting the visual images captured by a video-camera into the equivalent auditory images, or "soundscapes". Here, it was used by blindfolded sighted participants to learn the spatial position of simple shapes depicted... περισσότερα »

Design and Development of a Clinical Risk Management Tool Using Radio Frequency Identification (RFID).

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 23 δευτερόλεπτα

*Design and Development of a Clinical Risk Management Tool Using Radio Frequency Identification (RFID).* Acta Inform Med. 2016 Apr;24(2):111-5 Authors: Pourasghar F, Tabrizi JS, Yarifard K Abstract BACKGROUND: Patient safety is one of the most important elements of quality of healthcare. It means preventing any harm to the patients during medical care process. OBJECTIVE: This paper introduces a cost-effective tool in which the Radio Frequency Identification (RFID) technology is used to identify medical errors in hospital. METHODS: The proposed clinical error management system (CEM... περισσότερα »

Surgical Vision: Google Glass and Surgery.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 23 δευτερόλεπτα

*Surgical Vision: Google Glass and Surgery.* Surg Innov. 2016 May 3; Authors: Chang JY, Tsui LY, Yeung KS, Yip SW, Leung GK Abstract Google Glass is, in essence, a smartphone in the form of a pair of spectacles. It has a display system, a bone conduction "speaker," video camera, and connectivity via WiFi or Bluetooth technologies. It can also be controlled by voice command. Seizing Google Glass' capabilities as windows of opportunity, surgeons have been the first group of doctors trying to incorporate the technology into their daily practices. Experiences from different groups ha... περισσότερα »

Sharing of Investigational Drug Among Participants in the Voice Trial.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 23 δευτερόλεπτα

*Sharing of Investigational Drug Among Participants in the Voice Trial.* AIDS Behav. 2016 May 4; Authors: Moodley J, Naidoo S, Moodley J, Ramjee G Abstract Product sharing among participants can impact on adherence and compromise the outcome in clinical trials. We describe incidents of product sharing at the Durban clinical research sites conducting the VOICE trial. The Durban sites enrolled 2750 women with 1103 and 1647 participants randomized to the vaginal gel and oral tablet arms respectively. Monthly pill and applicator counts including product assessments were conducted by p...περισσότερα »

Perceptual evaluation of tracheoesophageal speech: Is it a reliable tool?

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 23 δευτερόλεπτα

*Perceptual evaluation of tracheoesophageal speech: Is it a reliable tool?* Indian J Cancer. 2016 Jan-Mar;53(1):127-31 Authors: Suhail IS, Kazi RA, Jagade M Abstract Perceptual voice evaluation is a common clinical tool for rating the severity of vocal quality impairment. It has been used in research as a gold standard for comparison with acoustic and aerodynamics measurements. Nevertheless, it has disadvantages in the form of being time-consuming, a group of raters is needed and last but not the least it is a subjective manner of evaluation. Intraobserver and interobserver reliab... περισσότερα »

Nonverbal and paraverbal behavior in (simulated) medical visits related to genomics and weight: a role for emotion and race.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 23 δευτερόλεπτα

*Nonverbal and paraverbal behavior in (simulated) medical visits related to genomics and weight: a role for emotion and race.* J Behav Med. 2016 May 4; Authors: Persky S, Ferrer RA, Klein WM Abstract It is crucial to examine patient reactions to genomics-informed approaches to weight management within a clinical context, and understand the influence of patient characteristics (here, emotion and race). Examining nonverbal reactions offers a window into patients' implicit cognitive, attitudinal and affective processes related to clinical encounters. We simulated a weight management...περισσότερα »

Group mindfulness-based intervention for distressing voices: A pragmatic randomised controlled trial.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 23 δευτερόλεπτα

*Group mindfulness-based intervention for distressing voices: A pragmatic randomised controlled trial.* Schizophr Res. 2016 Apr 14; Authors: Chadwick P, Strauss C, Jones AM, Kingdon D, Ellett L, Dannahy L, Hayward M Abstract Group Person-Based Cognitive Therapy (PBCT) integrates cognitive therapy and mindfulness to target distinct sources of distress in psychosis. The present study presents data from the first randomised controlled trial investigating group PBCT in people distressed by hearing voices. One-hundred and eight participants were randomised to receive either group PBC...περισσότερα »

Comparison of self and proxy ratings for voice handicap index and motor-related quality-of-life of individuals with Parkinson's disease.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 23 δευτερόλεπτα

*Comparison of self and proxy ratings for voice handicap index and motor-related quality-of-life of individuals with Parkinson's disease.* Int J Speech Lang Pathol. 2016 May 5;:1-10 Authors: Parveen S, Goberman AM Abstract PURPOSE: Quality-of-life (QoL) consists of health, psychological well-being and communication-related domains. Due to the heterogeneous nature of Parkinson disease (PD), it is important to examine effects of different domains including motor and cognitive performance or motor and speech performance among the same set of individuals. Existing studies indicate mi... περισσότερα »

Transsexual Voice Questionnaire for Male-to-female Brazilian Transsexual People.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 23 δευτερόλεπτα

*Transsexual Voice Questionnaire for Male-to-female Brazilian Transsexual People.* J Voice. 2016 Apr 14; Authors: Schwarz K, Fontanari AM, Mueller A, Costa AB, Soll B, da Silva DC, Cielo CA, Kuhl G, Spritzer PM, Schneider MA, Dorfmann ME, Lobato MI Abstract OBJECTIVES: The aim of the study was to verify the answers to the transsexual voice questionnaire for male-to-female transsexual (TVQ(MtF)) people given to individuals who participated in the Gender Identity Program (PROTIG) at the Hospital de Clínicas de Porto Alegre, Brazil, in relation to some of their demographic character...περισσότερα »

Regio- and Stereochemical Control in Ocimene Polymerization by Half-Sandwich Rare-Earth Metal Dialkyl Complexes

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 24 δευτερόλεπτα

The polymerization of ocimene has been first achieved by half-sandwich rare-earth metal dialkyl complexes in combination with activator and Al*i*Bu 3. The regio- and stereoselectivity in the ocimene polymerization can be controlled by tuning the cyclopentadienyl ligand and the central metal of the complex. The chiral cyclopentadienyl-ligated Sc complex *1* prepares syndiotactic *cis*-1,4-polyocimene (*cis*-1,4-selectivity up to 100%, rrrr = 100%), while the corresponding Lu, Y, and Dy complexes *2*–*4* and the achiral pentamethylcyclopentadienyl Sc, Lu, and Y complexes *5*–*7* affo... περισσότερα »

Aptamers, antibody scFv, and antibody Fab' fragments: An overview and comparison of three of the most versatile biosensor biorecognition elements

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 24 δευτερόλεπτα

[image: S09565663.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): Victor Crivianu-Gaita, Michael Thompson The choice of biosensing elements is crucial for the development of the optimal biosensor. Three of the most versatile biosensing elements are antibody single-chain Fv fragments (scFv), antibody fragment-antigen binding (Fab') units, and aptamers. This article provides an overview of these three biorecognition elements with respects to their synthesis/engineering, various immobilization techniques, and examples of their use in... περισσότερα »

Further delineation of FKBP14-related Ehlers-Danlos syndrome: A patient with early vascular complications and non-progressive kyphoscoliosis, and literature review.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

Child abuse and fabricated or induced illness in the ENT setting: a systematic review.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

Salivary FOXP2 expression and oral feeding success in premature infants.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

FOXP2 gene deletion and infant feeding difficulties: a case report.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

Gastroscopic removal of a giant fibrovascular polyp from the esophagus.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

Clinical features and prognosis in anti-SRP and anti-HMGCR necrotising myopathy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

A Preliminary Study of How the Viscosity of Dietary Fluids and Videofluoroscopy Fluids can be Matched.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

[Transthoracic myotomy of a case of giant megaesophagus in Mali hospital].

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

[image: http:--http://ift.tt/1MOzwGw] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *[Transthoracic myotomy of a case of giant megaesophagus in Mali hospital].* Pan Afr Med J. 2015;21:239 Authors: Togo S, Abdoulaye OM, Xing L, Sadio Y PMID: 26523179 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1rxUNBM via IFTTT

Randomised clinical trial: transoral incisionless fundoplication vs. sham intervention to control chronic GERD.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

Delayed hypersensitivity reaction after cervical disc replacement: a case report.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

Comparison of self and proxy ratings for voice handicap index and motor-related quality-of-life of individuals with Parkinson’s disease

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

10.3109/17549507.2016.1167242 Sabiha Parveen from Speech via a.lsfakia on Inoreader http://ift.tt/26ZtSiz via IFTTT

Gastroesophageal reflux and lung disease.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 25 δευτερόλεπτα

Effect of body mass index on operative outcome after robotic-assisted Ivor-Lewis esophagectomy: retrospective analysis of 129 cases at a single high-volume tertiary care center.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*Effect of body mass index on operative outcome after robotic-assisted Ivor-Lewis esophagectomy: retrospective analysis of 129 cases at a single high-volume tertiary care center.* Dis Esophagus. 2016 May 4; Authors: Salem AI, Thau MR, Strom TJ, Abbott AM, Saeed N, Almhanna K, Hoffe SE, Shridhar R, Karl RC, Meredith KL Abstract The impact of body weight on outcomes after robotic-assisted esophageal surgery for cancer has not been studied. We examined the short-term operative outcomes in patients according to their body mass index following robotic-assisted Ivor-Lewis esophagectomy...περισσότερα »

Potential of Baseline Computed Tomography to Predict Long-Term Survival of Patients With Locally Advanced Esophageal Cancer Treated With Preoperative Chemotherapy: A Retrospective Cohort Study.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*Potential of Baseline Computed Tomography to Predict Long-Term Survival of Patients With Locally Advanced Esophageal Cancer Treated With Preoperative Chemotherapy: A Retrospective Cohort Study.* Medicine (Baltimore). 2016 May;95(18):e3583 Authors: Wang ZL, Chen Y, Li XT, Chen KN, Sun YS Abstract In this study, we evaluated the efficacy of baseline computed tomography (CT) signs and postoperative TN stages on survival of patients with advanced esophageal squamous cell carcinoma with preoperative chemotherapy. Consecutive patients (n = 130) with preoperative chemotherapy and radica... περισσότερα »

Simultaneous Resection of Synchronous Esophageal and Gastric Cancers.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*Simultaneous Resection of Synchronous Esophageal and Gastric Cancers.* Thorac Cardiovasc Surg. 2016 May 5; Authors: Park B, Kim HK, Choi YS, Kim J, Zo JI, Shim YM Abstract Background In patients with synchronous esophageal and gastric cancers, selecting an optimal conduit for esophageal reconstruction is a critical decision. The aim of this study was to evaluate the surgical outcomes after simultaneous resection of esophageal and gastric cancers according to the type of esophageal conduit used. Materials and Methods Clinicopathologic features and surgical outcomes were analyzed i...περισσότερα »

Association between Postoperatively Developed Atrial Fibrillation and Long-Term Mortality after Esophagectomy in Esophageal Cancer Patients: An Observational Study.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*Association between Postoperatively Developed Atrial Fibrillation and Long-Term Mortality after Esophagectomy in Esophageal Cancer Patients: An Observational Study.* PLoS One. 2016;11(5):e0154931 Authors: Chin JH, Moon YJ, Jo JY, Han YA, Kim HR, Lee EH, Choi IC Abstract BACKGROUND: Newly developed atrial fibrillation (AF) in patients who have undergone an esophagectomy increases the incidence of postoperative complications. However, the clinical implications of AF have not been fully elucidated in these patients. This retrospective observational study investigated the predictors...περισσότερα »

Gastroscopic removal of a giant fibrovascular polyp from the esophagus.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

Patient features predicting long-term survival and health-related quality of life after radical surgery for non-small cell lung cancer.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*Patient features predicting long-term survival and health-related quality of life after radical surgery for non-small cell lung cancer.* Thorac Cancer. 2016 Apr 26;7(3):333-9 Authors: Rauma V, Salo J, Sintonen H, Räsänen J, Ilonen I Abstract BACKGROUND: This study presents a retrospective evaluation of patient, disease, and treatment features predicting long-term survival and health-related quality of life (HRQoL) among patients who underwent surgery for non-small cell lung cancer (NSCLC). METHODS: Between January 2000 and June 2009, 586 patients underwent surgery at the Helsinki... περισσότερα »

High expression of cyclooxygenase 2 is an indicator of prognosis for patients with esophageal squamous cell carcinoma after Ivor Lewis esophagectomy.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*High expression of cyclooxygenase 2 is an indicator of prognosis for patients with esophageal squamous cell carcinoma after Ivor Lewis esophagectomy.* Thorac Cancer. 2016 Apr 26;7(3):310-5 Authors: Hu D, Zhang M, Wang S, Wang Z Abstract BACKGROUND: The poor prognosis of esophageal squamous cell carcinoma (ESCC) is attributed to a high recurrence rate after surgery. Cyclooxygenase 2 (COX2) is an important regulator of cell growth, differentiation, apoptosis, and transformation. COX2 overexpression is significantly associated with the tumorigenesis and progression of diverse cance... περισσότερα »

Cost-effectiveness of neoadjuvant concurrent chemoradiotherapy versus esophagectomy for locally advanced esophageal squamous cell carcinoma: A population-based matched case-control study.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*Cost-effectiveness of neoadjuvant concurrent chemoradiotherapy versus esophagectomy for locally advanced esophageal squamous cell carcinoma: A population-based matched case-control study.* Thorac Cancer. 2016 Apr 26;7(3):288-95 Authors: Lin CY, Fang HY, Feng CL, Li CC, Chien CR Abstract BACKGROUND: Neoadjuvant concurrent chemoradiotherapy (NCCRT) is often considered for locally-advanced esophageal squamous cell carcinoma (LA-ESCC) patients; however, no data regarding the cost-effectiveness of this treatment is available. Our study aimed to evaluate the cost-effectiveness of NCCR... περισσότερα »

Determination of radiotherapeutic target zones for thoracic esophageal squamous cell cancer with lower cervical lymph node metastasis according to CT-images.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*Determination of radiotherapeutic target zones for thoracic esophageal squamous cell cancer with lower cervical lymph node metastasis according to CT-images.* Oncotarget. 2016 Apr 28; Authors: Li X, Zhao J, Liu M, Zhai F, Zhu Z, Yu F, Zhang M, Han L, Zhao Y, Wang H Abstract Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer-related deaths worldwide. And radical synchronized chemoradiotherapy has become an important treatment measures for this disease. It is necessary to define the therapeutic target zone based on computer tomography(CT)-images for precise ra... περισσότερα »

The epithelial-mesenchymal transition phenotype of metastatic lymph nodes impacts the prognosis of esophageal squamous cell carcinoma patients.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*The epithelial-mesenchymal transition phenotype of metastatic lymph nodes impacts the prognosis of esophageal squamous cell carcinoma patients.* Oncotarget. 2016 Apr 27; Authors: Wen J, Luo KJ, Liu QW, Wang G, Zhang MF, Xie XY, Yang H, Fu JH, Hu Y Abstract Epithelial-mesenchymal transition (EMT) plays a key role in tumor metastasis, but the significance of EMT phenotype to the prognosis of esophageal squamous cell carcinoma (ESCC) patients remains unclear. We used immunohistochemistry to examine the expression of the EMT-related proteins E-cadherin, N-cadherin and vimentin in sa... περισσότερα »

A Dirichlet process mixture model for automatic (18)F-FDG PET image segmentation: Validation study on phantoms and on lung and esophageal lesions.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*A Dirichlet process mixture model for automatic (18)F-FDG PET image segmentation: Validation study on phantoms and on lung and esophageal lesions.* Med Phys. 2016 May;43(5):2491 Authors: Giri MG, Cavedon C, Mazzarotto R, Ferdeghini M Abstract PURPOSE: The aim of this study was to implement a Dirichlet process mixture (DPM) model for automatic tumor edge identification on (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) images by optimizing the parameters on which the algorithm depends, to validate it experimentally, and to test its robustness. METHODS: The D... περισσότερα »

Spirometric Lung Age Predicts Postoperative Pneumonia After Esophagectomy.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 30 δευτερόλεπτα

*Spirometric Lung Age Predicts Postoperative Pneumonia After Esophagectomy.* World J Surg. 2016 May 4; Authors: Okamura A, Watanabe M, Mine S, Nishida K, Kurogochi T, Imamura Y Abstract BACKGROUND: Despite advances in treatment, postoperative pneumonia remains a major problem after esophagectomy. Lung age has been proposed as a comprehensive indicator for respiratory function. The aim of this study is to reveal the efficacy of lung age in predicting occurrence of pneumonia after esophagectomy. METHODS: We assessed 342 consecutive patients who underwent subtotal esophagectomy for p... περισσότερα »

Oesophageal signet ring cell carcinoma as complication of gastro-oesophageal reflux disease.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 34 δευτερόλεπτα

Prognostic significance of prospectively detected bone marrow micrometastases in esophagogastric cancer: 10-year follow-up confirms prognostic significance.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 34 δευτερόλεπτα

[image: http:--media.wiley.com-assets-7315-18-Wi] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Prognostic significance of prospectively detected bone marrow micrometastases in esophagogastric cancer: 10-year follow-up confirms prognostic significance.* Cancer Med. 2015 Aug;4(8):1281-8 Authors: Ryan P, Furlong H, Murphy CG, O'Sullivan F, Walsh TN, Shanahan F, O'Sullivan GC Abstract We have previously reported that most patients with esophagogastric cancer (EGC) undergoing potentially curative resections have bone marrow micrometastases (BMM). We present 10-year outcome...περισσότερα »

Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 34 δευτερόλεπτα

The Durability of Endoscopic Therapy for Treatment of Barrett's Metaplasia, Dysplasia, and Mucosal Cancer After Nissen Fundoplication.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 34 δευτερόλεπτα

[image: http:--production.springer.de-OnlineReso] Related Articles *The Durability of Endoscopic Therapy for Treatment of Barrett's Metaplasia, Dysplasia, and Mucosal Cancer After Nissen Fundoplication.* J Gastrointest Surg. 2015 May;19(5):799-805 Authors: Johnson CS, Louie BE, Wille A, Dunst CM, Worrell SG, DeMeester SR, Reynolds J, Dixon J, Lipham JC, Lada M, Peters JH, Watson TJ, Farivar AS, Aye RW Abstract INTRODUCTION: Radiofrequency ablation (RFA) ± endoscopic resection (EMR) is an established treatment strategy for neoplastic Barrett's and intramucosal cancer. Most patient... περισσότερα »

Niche nanoparticle-based FRET assay for bleomycin detection via DNA scission

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 38 δευτερόλεπτα

[image: S09565663.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): Haimeng Pei, Yiqun Zheng, Rongmei Kong, Lian Xia, Fengli Qu We describe a highly sensitive nanoparticle–based fluorescence resonance energy transfer (FRET) probe developed without using molecular fluorophores as donors and acceptors. The success of this work relies on the strategy that DNA scission was designed to occur to the probe when target presented, which enabled the fluorescence signal "turn-on" of graphene quantum dots (GQDs) and thus quantitative analysis. I... περισσότερα »

Coupling non invasive and fast sampling of proteins from work of art surfaces to surface plasmon resonance biosensing: Differential and simultaneous detection of egg components for cultural heritage diagnosis and conservation

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 38 δευτερόλεπτα

[image: S09565663.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): S. Scarano, E. Carretti, L. Dei, P. Baglioni, M. Minunni Despite the wide application of surface plasmon resonance (SPR) to a broad area of interests, from environment to food analysis, from drug discovery to diagnostics, its exploitation in cultural heritage conservation is still unexplored. Water-based highly viscous polymeric dispersions (HVPD) composed by partially hydrolyzed polyvinyl acetate (PVA), borax, and water, were recently developed and successfully appl... περισσότερα »

Gastroesophageal reflux and lung disease.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 39 δευτερόλεπτα

Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 39 δευτερόλεπτα

More art than science: impedance analysis prone to interpretation error.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 39 δευτερόλεπτα

Enhanced non-vitreous cryopreservation of immortalized and primary cells by ice-growth inhibiting polymers

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 39 δευτερόλεπτα

[image: GA?id=C6BM00129G] *Biomater. Sci.*, 2016, Advance Article *DOI*: 10.1039/C6BM00129G, Paper [image: Open Access] Open Access [image: Creative Commons Licence] This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Robert C. Deller, Jeffrey E. Pessin, Manu Vatish, Daniel A. Mitchell, Matthew I. Gibson Ice growth inhibiting polymers are shown to enhance the (non-vitrifying) cryopreservation of several cell lines and also primary hepatocytes. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of th...περισσότερα »

Patient-physician communication is critical for prostate cancer survivors’ health

For prostate cancer patients who had their prostates surgically removed, patient-physician communication was key for helping them cope with their disease and for improving their health-related quality of life. The authors of the 1772-patient study note… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Xc5F4h via IFTTT

Centromere core core found to be highly concerved, shields itself from DNA damage

The centromere, the structure at the crossroads of chromosomes, is among the least explored regions of DNA. The genetic material there is extremely concentrated, and the sequences highly repetitive. Using a combination of proteomics and electron… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TrzlV3 via IFTTT

Regulator of death receptor discovered

Researchers at IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences have discovered that an enzyme called HACE1 is the key regulator of the death receptor TNFR1. The TNF receptor 1 is located on the cell membrane and decides… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Xc5F44 via IFTTT

ESCRT machinery: Damage control at the nuclear membrane

ESCRT machinery: Damage control at the nuclear membrane Cell Research advance online publication, May 6 2016. doi:10.1038/cr.2016.52 Authors: Leandro N Ventimiglia & Juan Martin-Serrano from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1rxeqta via IFTTT

Applications of Replicating-Competent Reporter-Expressing Viruses in Diagnostic and Molecular Virology

Commonly used tests based on wild-type viruses, such as immunostaining, cannot meet the demands for rapid detection of viral replication, high-throughput screening for antivirals, as well as for tracking viral proteins or virus transport in real time. Notably, the development of replicating-competent reporter-expressing viruses (RCREVs) has provided an excellent option to detect directly viral replication […]

Central Artery Perforator Propeller Flap For Nasal And Medial Canthal Defects

Non-melanoma skin cancer is the most common type of skin cancer of the nasal dorsum and medial canthal region caused by chronic sun exposure. Limited adjacent tissue and the need of aesthetically appealing result make the reconstruction of those regions very challenging. To overcome this challenge, we designed a perforator propeller flap based on central […]

General morphology and ultrastructure of the female reproductive apparatus of Trichomalopsis shirakii crawford (Hymenoptera, Pteromalidae)

ABSTRACT The morphology and ultrastructure of the female reproductive system were examined for a larval–pupal parasitoid Trichomalopsis shirakii Crawford of Oulema oryzae Kuwayama using light and electron microscopes. The reproductive system includes two ovaries, two pairs of accessory glands, an unbranched venom gland, a large venom reservoir and a Dufour gland. Each ovariole contains follicles […]

The external morphology of adult female Egrasilus labracis as shown using hexamethyldisilazane treated, uncoated specimens for scanning electron microscopy

ABSTRACT The description and application of a modified Scanning Electron Microscope preparation technique using hexamethyldisilazane for small parasitic copepods was demonstrated though a high resolution depiction of individuals of Ergasilus labracis sampled from three spined stickleback (Gasterosteus aculeatus) in Bay D’Espoir, Newfoundland during summer 2015 and from archival samples retrieved from Atlantic salmon par (Salmo […]

Pseudoarthrosis of the ilium after periacetabular osteotomy that was treated by cemented total hip arthroplasty: a case report

Preserving the hip joint to delay arthroplasty for patients with acetabular dysplasia-associated early-stage osteoarthritis has become more common, and several surgical procedures have demonstrated pain relief… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1WNny8Y via IFTTT

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. Am J Hum Genet. 2016 Apr 7;98(4):680-96 Authors: Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu CJ, Küpers LK, Oh SS, Hoyo C, Gruzieva O, Söderhäll C, Salas LA, Baïz N, Zhang […]

Music therapy in patients with high-dose chemotherapy and stem cell support: a randomized pilot study

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

a randomized pilot study: Abstract Objective Patients with high dose chemotherapy (HDC) with autologous stem cell transplantation (ASCT) are highly distressed. Psycho-oncological support might be beneficial but is not routinely provided. Our aim was to investigate whether music therapy (MT) in addition to standard supportive treatment had any effect on quality of life, depression, anxiety, side effects of therapy, medication, and immunological changes during and within three months after HDC plus ASCT. Methods Patients (n = 66) with HDC plus ASCT were randomly assigned to either MT... περισσότερα »

Sleep in hospitalized pediatric cancer patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

A systematic review of Abstract Objective The purpose of this systematic review was to describe the occurrence of sleep disruptions in pediatric cancer patients and to identify and discuss the factors related to the hospital sleep environment that may be associated with disturbed sleep. Methods A total of 108 articles were located in five databases (PubMed, PsychINFO, Medline, CancerLit, and Google Scholar), and seven met our inclusion criteria and formed the basis of this review. Results Participants ranged from 1 to 18 years (*n* = 147). Data from objective and subjective assessme...περισσότερα »

HIF inhibitors for ischemic retinopathies and cancers

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

options beyond anti-VEGF therapies: AbstractAberrant activation of the hypoxia inducible factor (HIF) pathway causing overexpression of angiogenic genes, like vascular endothelial growth factor (VEGF), is one of the underlying causes of ocular neovascularization (NV) and metastatic cancer. Consistently, along with surgical interventions, a number of anti-VEGF agents have been approved by FDA for the treatment of ocular neovascular diseases. These anti-VEGF agents, like ranibizumab/lucentis, have revolutionized the treatment in the past decade. However, substantial vision improveme...περισσότερα »

Cervicothoracic cystic dysraphism

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

Cervicothoracic cystic dysraphism: AbstractCystic dysraphism of the cervical and upper thoracic spine is very rare. It differs from the much more common lumbosacral dysraphism in appearance and structure, and usually portends a better prognosis due to lack of functional neurological tissue in the dysraphic sac and absent or less severe intracranial anomalies. There is ambiguity in the literature regarding terminology because of the paucity of cases. We present cases of the most common type of cervicothoracic cystic dysraphism and emphasize differences from lumbosacral myelomeningoc... περισσότερα »

A new prognostic histopathologic classification of nasopharyngeal carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

A new prognostic histopathologic classification of nasopharyngeal carcinoma: Abstract BackgroundThe current World Health Organization (WHO) classification of nasopharyngeal carcinoma (NPC) conveys little prognostic information. This study aimed to propose an NPC histopathologic classification that can potentially be used to predict prognosis and treatment response. MethodsWe initially developed a histopathologic classification based on the morphologic traits and cell differentiation of tumors of 2716 NPC patients who were identified at Sun Yat-sen University Cancer Center (SYSU...περισσότερα »

Management of Locally Advanced Carcinoma Oesophagus with Radiation/Chemoradiation: Single Institute Experience

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

Single Institute Experience: Abstract PurposeOesophageal malignancy is the fourth commonest cancer which has a very poor outcome. In the management of oesophageal malignancy, radiation therapy is underutilized by many physicians due to feared complications though its role is well proven in literature. This study brings the role of radiation therapy in terms of loco-regional and distant relapse. This study characterizes demographic characteristics, treatment modality and the impact of these on recurrence-free survival of locally advanced carcinoma oesophagus. MethodIn a retros... περισσότερα »

Bevacizumab and everolimus on vestibular schwannomas of patients with neurofibromatosis type 2

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

Mechanism-based modeling of the clinical effects of Abstract PurposeTo describe the natural growth of vestibular schwannoma in patients with neurofibromatosis type 2 and to predict tumor volume evolution in patients treated with bevacizumab and everolimus. MethodsClinical data, including longitudinal tumor volumes in patients treated by bevacizumab (*n* = 13), everolimus (*n* = 7) or both (*n* = 2), were analyzed by means of mathematical modeling techniques. Together with clinical data, data from the literature were also integrated to account for drugs mechanisms of action. ... περισσότερα »

Cardiac safety of TAS-102 in patients with advanced solid tumors

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

Phase 1 study of Abstract PurposeTAS-102 is a novel oral agent combining the antineoplastic thymidine-based nucleoside analogue, trifluridine, and the thymidine phosphorylase inhibitor, tipiracil (molar ratio 1:0.5). TAS-102 has shown good activity in refractory metastatic colorectal cancer with acceptable safety. No QT prolongation was seen in clinical studies. This study aimed to investigate TAS-102 cardiac safety for regulatory requirements. MethodsThis was a phase 1, non-randomized study in adults with advanced solid tumors. Intensive QT assessments were conducted at baseli... περισσότερα »

Inflammation-based prognostic system predicts postoperative survival of esophageal carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

patients with normal preoperative serum carcinoembryonic antigen and squamous cell carcinoma antigen levels: Abstract BackgroundThe Glasgow Prognostic Score (GPS) is an established inflammation-based system that is used to predict the prognosis for several types of malignancies. In this retrospective study, we assessed the postoperative survival of 725 patients with non-metastatic esophageal squamous cell carcinoma who had normal preoperative serum tumor marker levels according to the GPS. MethodsAmong 1394 patients who underwent esophagectomy between August 2006 and December... περισσότερα »

The incidence of brain cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

Has the incidence of brain cancer risen in Australia since the introduction of mobile phones 29 years ago? via ScienceDirect Publication: Cancer Epidemiology (open access) Publication date: Available online 5 May 2016 *Source:*Cancer Epidemiology Author(s): Simon Chapman, Lamiae Azizi, Qingwei Luo, Freddy Sitas BackgroundMobile phone use in Australia has increased rapidly since its introduction in 1987 with whole population usage being 94% by 2014. We explored the popularly hypothesised association between brain cancer incidence and mobile phone use.Study methodsUsing national cancer r... περισσότερα »

Linking High-Fat Diet to Stem Cell Dysfunction and Tumorigenesis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

You Are What You Eat: via Cell Stem Cell Publication date: 5 May 2016 *Source:*Cell Stem Cell, Volume 18, Issue 5 Author(s): Samantha Haller, Heinrich Jasper A high-fat diet is linked to elevated cancer risk, yet this link remains poorly understood. New studies in mice are now beginning to obtain mechanistic insight into how high-fat diets perturb stem cell function and cause cancers. TeaserA high-fat diet is linked to elevated cancer risk, yet this link remains poorly understood. New studies in mice are now beginning to obtain mechanistic insight into how high-fat diets perturb stem ... περισσότερα »

Understanding How Zika Virus Enters and Infects Neural Target Cells

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα

Understanding How Zika Virus Enters and Infects Neural Target Cells via Cell Stem Cell Publication date: 5 May 2016 *Source:*Cell Stem Cell, Volume 18, Issue 5 Author(s): Jonathan J. Miner, Michael S. Diamond Zika virus is a mosquito-transmitted flavivirus that has become a public health concern because of its ability to cause microcephaly. In this issue of Cell Stem Cell, Tang et al. (2016) and Nowakowski et al. (2016) use human neural stem cell models and single-cell RNA sequencing to investigate Zika virus tropism and potential entry receptors. TeaserZika virus is a mosquito-transmit...περισσότερα »

Randomised clinical trial: transoral incisionless fundoplication vs. sham intervention to control chronic GERD.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

Oesophageal signet ring cell carcinoma as complication of gastro-oesophageal reflux disease.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

Delayed hypersensitivity reaction after cervical disc replacement: a case report.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

Gastroesophageal reflux and lung disease.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

More art than science: impedance analysis prone to interpretation error.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

Perspectives on the role of the speech and language therapist in palliative care: An international survey.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

[Transthoracic myotomy of a case of giant megaesophagus in Mali hospital].

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

[image: http:--http://ift.tt/1MOzwGw] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *[Transthoracic myotomy of a case of giant megaesophagus in Mali hospital].* Pan Afr Med J. 2015;21:239 Authors: Togo S, Abdoulaye OM, Xing L, Sadio Y PMID: 26523179 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1rxUNBM via IFTTT

Randomised clinical trial: transoral incisionless fundoplication vs. sham intervention to control chronic GERD.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

Oesophageal signet ring cell carcinoma as complication of gastro-oesophageal reflux disease.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

Delayed hypersensitivity reaction after cervical disc replacement: a case report.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα

Extravasation Risk Using Ultrasound Guided Peripheral Intravenous Catheters for Computed Tomography Contrast Administration

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 45 δευτερόλεπτα

[image: cover.gif?v=1&s=a69cedb9789cb8bbbf032b71] Abstract Objective Ultrasound guided intravenous catheter (USGIV) insertion is increasingly being used for administration of intravenous contrast for computed tomography (CT) scans. The goal of this investigation was to evaluate the risk of contrast extravasation among patients receiving contrast through USGIV catheters. Methods A retrospective observational study of adult patients who underwent a contrast-enhanced CT scan at a tertiary-care emergency department during a recent 64-month period was conducted. The unadjusted preva...περισσότερα »

Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 46 δευτερόλεπτα

More art than science: impedance analysis prone to interpretation error.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 46 δευτερόλεπτα

Semantic biomedical resource discovery: a Natural Language Processing framework.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

Related Articles *Semantic biomedical resource discovery: a Natural Language Processing framework.* BMC Med Inform Decis Mak. 2015;15:77 Authors: Sfakianaki P, Koumakis L, Sfakianakis S, Iatraki G, Zacharioudakis G, Graf N, Marias K, Tsiknakis M Abstract BACKGROUND: A plethora of publicly available biomedical resources do currently exist and are constantly increasing at a fast rate. In parallel, specialized repositories are been developed, indexing numerous clinical and biomedical tools. The main drawback of such repositories is the difficulty in locating appropriate resources f... περισσότερα »

Developing an assessment approach for perceptual changes to tinnitus sound characteristics for adult cochlear implant recipients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

*Developing an assessment approach for perceptual changes to tinnitus sound characteristics for adult cochlear implant recipients.* Int J Audiol. 2016 May 5;:1-13 Authors: Greenberg D, Meerton L, Graham J, Vickers D Abstract OBJECTIVE: To investigate the impact of cochlear implantation on tinnitus suppression, characteristics, localization, and duration. DESIGN: A cochlear implant (CI) recipient-focused postal questionnaire survey. STUDY SAMPLE: The questionnaire was posted, with consent, to 100 adults who had received a unilateral CI at the RNTNEH between 1988 and 1999. All adult...περισσότερα »

Rational Design of Bioelectrochemically Multifunctional Film with Oxidase, Ferrocene, and Graphene Oxide for Development of In Vivo Electrochemical Biosensors.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

*Rational Design of Bioelectrochemically Multifunctional Film with Oxidase, Ferrocene, and Graphene Oxide for Development of In Vivo Electrochemical Biosensors.* Anal Chem. 2016 May 5; Authors: Wang X, Li Q, Xu J, Wu S, Xiao T, Hao J, Yu P, Mao L Abstract This study demonstrates a new strategy to develop in vivo electrochemical biosensors through rational design and simple formation of bioelectrochemically multifunctional film (BMF). The BMF is rationally designed by first efficiently incorporating oxidase, ferrocene mediator, and graphene oxide into polymaleimidostyrene/polystyr...περισσότερα »

A systematic review of techniques and effects of self-help interventions for tinnitus: Application of taxonomies from health psychology.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

*A systematic review of techniques and effects of self-help interventions for tinnitus: Application of taxonomies from health psychology.* Int J Audiol. 2016 May 5;:1-11 Authors: Greenwell K, Sereda M, Coulson N, El Refaie A, Hoare DJ Abstract OBJECTIVE: Self-help interventions are followed by people independently with minimal or no therapist contact. This review aims to assess the effectiveness of self-help interventions for adults with chronic tinnitus and systematically identify the self-help techniques used. DESIGN: Systematic review and application of health psychology taxonom... περισσότερα »

Modulation of Specific Sensory Cortical Areas by Segregated Basal Forebrain Cholinergic Neurons Demonstrated by Neuronal Tracing and Optogenetic Stimulation in Mice.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

*Modulation of Specific Sensory Cortical Areas by Segregated Basal Forebrain Cholinergic Neurons Demonstrated by Neuronal Tracing and Optogenetic Stimulation in Mice.* Front Neural Circuits. 2016;10:28 Authors: Chaves-Coira I, Barros-Zulaica N, Rodrigo-Angulo M, Núñez Á Abstract Neocortical cholinergic activity plays a fundamental role in sensory processing and cognitive functions. Previous results have suggested a refined anatomical and functional topographical organization of basal forebrain (BF) projections that may control cortical sensory processing in a specific manner. We ...περισσότερα »

Effect of transcranial direct current stimulation (tDCS) on MMN-indexed auditory discrimination: a pilot study.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

[image: http:--production.springer.de-OnlineReso] Related Articles *Effect of transcranial direct current stimulation (tDCS) on MMN-indexed auditory discrimination: a pilot study.* J Neural Transm (Vienna). 2015 Aug;122(8):1175-85 Authors: Impey D, Knott V Abstract Membrane potentials and brain plasticity are basic modes of cerebral information processing. Both can be externally (non-invasively) modulated by weak transcranial direct current stimulation (tDCS). Polarity-dependent tDCS-induced reversible circumscribed increases and decreases in cortical excitability and functional ... περισσότερα »

The Temporal Cascade of Neural Processes Underlying Target Detection and Attentional Processing During Auditory Search.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

[image: http:--highwire.stanford.edu-icons-exter] Related Articles *The Temporal Cascade of Neural Processes Underlying Target Detection and Attentional Processing During Auditory Search.* Cereb Cortex. 2015 Sep;25(9):2456-65 Authors: Gamble ML, Woldorff MG Abstract The posterior visual event-related potential (ERP) component, the N2pc, has been widely used to study lateralized shifts of attention within visual arrays. Recently, Gamble and Luck (2011) reported an auditory analog of this activity (the fronto-central "N2ac"), reflecting the lateralized focusing of attention toward ... περισσότερα »

Future Oncology

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

33 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Future Oncology* These pubmed results were generated on 2016/05/06 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/26Ztxwn via IFTTT

Novel Radiofrequency Ablation Strategies for Terminating Atrial Fibrillation in the Left Atrium: A Simulation Study.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

*Novel Radiofrequency Ablation Strategies for Terminating Atrial Fibrillation in the Left Atrium: A Simulation Study.* Front Physiol. 2016;7:108 Authors: Bayer JD, Roney CH, Pashaei A, Jaïs P, Vigmond EJ Abstract Pulmonary vein isolation (PVI) with radiofrequency ablation (RFA) is the cornerstone of atrial fibrillation (AF) therapy, but few strategies exist for when it fails. To guide RFA, phase singularity (PS) mapping locates reentrant electrical waves (rotors) that perpetuate AF. The goal of this study was to test existing and develop new RFA strategies for terminating rotors ... περισσότερα »

Quantitative Analysis of the Isolation Area During the Chronic Phase After a 28-mm Second-Generation Cryoballoon Ablation Demarcated by High-Resolution Electroanatomic Mapping.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

*Quantitative Analysis of the Isolation Area During the Chronic Phase After a 28-mm Second-Generation Cryoballoon Ablation Demarcated by High-Resolution Electroanatomic Mapping.* Circ Arrhythm Electrophysiol. 2016 May;9(5):e003879 Authors: Miyazaki S, Taniguchi H, Hachiya H, Nakamura H, Takagi T, Iwasawa J, Hirao K, Iesaka Y Abstract BACKGROUND: The post-second-generation cryoballoon (CB) ablation isolation area during the chronic phase has not been described. The aim of this study was to quantitatively evaluate the chronic-phase isolation area after 28-mm second-generation CB ab... περισσότερα »

[Oligometastasized stage IV colorectal cancer : Surgical resection and local ablative procedures].

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

*[Oligometastasized stage IV colorectal cancer : Surgical resection and local ablative procedures].* Chirurg. 2016 May 4; Authors: Binnebösel M, Bruners P, Klink CD, Kuhl C, Neumann UP Abstract BACKGROUND: By the intensified combination of systemic, surgical and local ablative therapies a significant improvement in therapy results for metastasized colorectal cancer has been achieved in the last decade. Downstaging with subsequent resection is nowadays a standard for oligometastasized primarily unresectable colorectal cancer. MATERIAL AND METHODS: The value of combining resection a... περισσότερα »

Safety and efficacy of radiofrequency wire recanalization of chronic central venous occlusions.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

[image: http:--http://ift.tt/26ZtyQJ] Related Articles *Safety and efficacy of radiofrequency wire recanalization of chronic central venous occlusions.* J Vasc Access. 2015 Jul-Aug;16(4):309-14 Authors: Sivananthan G, MacArthur DH, Daly KP, Allen DW, Hakham S, Halin NJ Abstract PURPOSE: The purpose of this study is to evaluate the safety and efficacy of using a radiofrequency wire (RF) for central venous occlusion (CVO) recanalization after failure using conventional techniques. MATERIALS AND METHODS: A retrospective analysis of all central venous recanalization procedures using a... περισσότερα »

Alleviation of pain in painful diabetic neuropathy.

Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα

*Alleviation of pain in painful diabetic neuropathy.* Expert Opin Drug Metab Toxicol. 2016 May 5; Authors: Tajti J, Szok D, Majláth Z, Csáti A, Petrovics-Balog A, Vécsei L Abstract INTRODUCTION: Painful diabetic neuropathy (PDN) is a disabling pain condition. Its pathomechanism remains unknown, but a sensitization and neuronal hyperexcitabilty have been suggested. Only symptomatic pharmacological pain management treatment is currently available. Areas covered: The origin of PDN is enigmatic, and the evidence-based therapeutic guidelines therefore consist only of antidepressants an...περισσότερα »

Variations in Training of Surgical Oncologists

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα

Proposal for a Global Curriculum: Abstract BackgroundThe global cancer burden is predicted to rise significantly over the next few decades. While there are several barriers to providing optimal cancer care on the global stage, some are related to the absence of an adequately trained workforce. This could be attributed in part to the significant global variations in the training of surgical oncology professionals. There are currently no published data mapping the training pathways for surgical oncologists for all countries in the world. The aims of this descriptive article are to ... περισσότερα »

Anthroposophic Medicine

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα

Individualized Integrative Cancer Care in Anthroposophic Medicine: A Qualitative Study of the Concepts and Procedures of Expert Doctors: *Background*. Cancer patients widely seek integrative oncology which embraces a wide variety of treatments and system approaches. *Objective*. To investigate the concepts, therapeutic goals, procedures, and working conditions of integrative oncology doctors in the field of anthroposophic medicine. *Methods*. This qualitative study was based on in-depth interviews with 35 highly experienced doctors working in hospitals and office-based practices in...περισσότερα »

Neuropsychological Interventions on Cognitive Function

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα

Meta-Analysis of the Effects of Neuropsychological Interventions on Cognitive Function in Non-Central Nervous System Cancer Survivors: *Background*. Cognitive impairment is a common complaint among cancer survivors, significantly impacting working memory, attention, executive function, and information processing speed. This meta-analysis aims to evaluate the effect of neuropsychological interventions on the cognitive function of non–central nervous system (non-CNS) cancer survivors. *Methods*. Three databases (PubMed, PsycInfo, and CAJ Full-text Database) were searched from January... περισσότερα »

Docetaxel-Induced Edema

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα

Chrysin Increases the Therapeutic Efficacy of Docetaxel and Mitigates Docetaxel-Induced Edema: Docetaxel (DTX) is an effective commercial anticancer agent for chemotherapy in non–small cell lung cancer (NSCLC), breast cancer, gastric cancer, and prostate cancer, but its adverse effects including edema, neurotoxicity, and hair loss limit its application. To improve the chemotherapeutic efficacy of DTX and reduce adverse effects, combination therapy is one of the alternative methods. So chrysin, which has various biological activities including anticancer effects, was considered. In ... περισσότερα »

Posaconazole Inhibits the Hedgehog Signaling Pathway

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα

Posaconazole Inhibits the Hedgehog Signaling Pathway: Deregulation of Hedgehog (Hh) pathway signaling has been associated with the pathogenesis of various malignancies, including basal cell carcinomas (BCC). Inhibitors of the Hh pathway currently available or under clinical investigation all bind and antagonize Smoothened (SMO), inducing a marked but transient clinical response. Tumor regrowth and therapy failure were attributed to mutations in the binding site of these small-molecule SMO antagonists. The antifungal itraconazole was demonstrated to be a potent SMO antagonist with a...περισσότερα »

Oncolytic Virotherapy with Reovirus

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα

The Future of The dominant cancer treatment modalities such as chemotherapy, radiotherapy, and even targeted kinase inhibitors and mAbs are limited by low efficacy, toxicity, and treatment-resistant tumor subclones. Oncolytic viral therapy offers a novel therapeutic strategy that has the potential to dramatically improve clinical outcomes. Reovirus, a double-stranded benign human RNA virus, is a leading candidate for therapeutic development and currently in phase III trials. Reovirus selectively targets transformed cells with activated Ras signaling pathways; Ras genes are some o... περισσότερα »

Continuation rate of atypical antipsychotics after discharge when initiated in the intensive care unit

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα

Journal of Pharmacy Practice from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1VMn583 via IFTTT

A healthy degree of suspicion: A discussion of the implementation of transmission based precautions in the emergency department

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα

Australasian Emergency Nursing Journal from Emergency Medicine via ola Kala on Inoreader http://ift.tt/23um5Vt via IFTTT

Middle-term mortality and re-bleeding after initial diverticular bleeding: A nationwide study of 365 mostly elderly French patients

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα

United European Gastroenterology Journal from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1VMn6ZG via IFTTT

Developing an assessment approach for perceptual changes to tinnitus sound characteristics for adult cochlear implant recipients.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

Oxidative stress biomarkers and otoacoustic emissions in humans exposed to styrene and noise.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

*Oxidative stress biomarkers and otoacoustic emissions in humans exposed to styrene and noise.* Int J Audiol. 2016 May 5;:1-9 Authors: Sisto R, Botti T, Cerini L, Sanjust F, Tranfo G, Bonanni RC, Paci E, Pigini D, Moleti A Abstract OBJECTIVE: Evaluating the correlation between otoacoustic emission levels, styrene exposure, and oxidative stress biomarkers concentration in styrene-exposed subjects, to investigate the role of oxidative stress in outer hair cell damage. DESIGN: Distortion product otoacoustic emissions were measured in the exposed workers and in a control group. Separ...περισσότερα »

A practical guide to cochlear implantation in adults with long durations of monaural sound deprivation.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

*A practical guide to cochlear implantation in adults with long durations of monaural sound deprivation.* Int J Audiol. 2016 May 5;:1-5 Authors: Boisvert I, McMahon CM, Dowell RC Abstract OBJECTIVE: This paper aims to summarize published findings by the authors and integrate these within current literature to support clinical guidelines when choosing an ear for cochlear implantation in adults with long-term monaural sound deprivation. STUDY SAMPLE: Four retrospective cohort studies based on data collected in five cochlear implantation centres with adults with bilateral hearing los... περισσότερα »

Book Review.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

*Book Review.* Int J Audiol. 2016 May 5;:1 Authors: Brennan M PMID: 27146131 [PubMed - as supplied by publisher] from #Audiology via ola Kala on Inoreader http://ift.tt/21Doaiu via IFTTT

A systematic review of techniques and effects of self-help interventions for tinnitus: Application of taxonomies from health psychology.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

Health behavior theories as predictors of hearing-aid uptake and outcomes.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

*Health behavior theories as predictors of hearing-aid uptake and outcomes.* Int J Audiol. 2016 May 5;:1-10 Authors: Saunders GH, Frederick MT, Silverman SC, Nielsen C, Laplante-Lévesque A Abstract OBJECTIVE: To understand hearing behaviors of adults seeking help for the first time through the application of two models of health behavior change: the transtheoretical model and the health belief model. DESIGN: The relationships between attitudes and beliefs were examined relative to hearing-aid uptake and outcomes six months later. STUDY SAMPLE: One hundred and sixty adults completed...περισσότερα »

Developing an assessment approach for perceptual changes to tinnitus sound characteristics for adult cochlear implant recipients

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

10.3109/14992027.2016.1172391 David Greenberg from #Audiology via ola Kala on Inoreader http://ift.tt/1WcjJeC via IFTTT

Oxidative stress biomarkers and otoacoustic emissions in humans exposed to styrene and noise

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

10.1080/14992027.2016.1177215 R. Sisto from #Audiology via ola Kala on Inoreader http://ift.tt/1STvdhk via IFTTT

A practical guide to cochlear implantation in adults with long durations of monaural sound deprivation

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

10.3109/14992027.2016.1166399 Isabelle Boisvert from #Audiology via ola Kala on Inoreader http://ift.tt/1WcjJew via IFTTT

Book Review

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

10.3109/14992027.2016.1166269 Marc Brennan from #Audiology via ola Kala on Inoreader http://ift.tt/1STvdhi via IFTTT

A systematic review of techniques and effects of self-help interventions for tinnitus: Application of taxonomies from health psychology

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

10.3109/14992027.2015.1137363 Kate Greenwell from #Audiology via ola Kala on Inoreader http://ift.tt/1WcjJeq via IFTTT

Health behavior theories as predictors of hearing-aid uptake and outcomes

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

10.3109/14992027.2016.1144240 Gabrielle H. Saunders from #Audiology via ola Kala on Inoreader http://ift.tt/1STvb95 via IFTTT

Developing an assessment approach for perceptual changes to tinnitus sound characteristics for adult cochlear implant recipients.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

Oxidative stress biomarkers and otoacoustic emissions in humans exposed to styrene and noise.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

A practical guide to cochlear implantation in adults with long durations of monaural sound deprivation.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

Book Review.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

*Book Review.* Int J Audiol. 2016 May 5;:1 Authors: Brennan M PMID: 27146131 [PubMed - as supplied by publisher] from #Audiology via ola Kala on Inoreader http://ift.tt/21Doaiu via IFTTT

A systematic review of techniques and effects of self-help interventions for tinnitus: Application of taxonomies from health psychology.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

Health behavior theories as predictors of hearing-aid uptake and outcomes.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα

Central Artery Perforator Propeller Flap For Nasal And Medial Canthal Defects

sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

A Preliminary Study of How the Viscosity of Dietary Fluids and Videofluoroscopy Fluids can be Matched.

Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα

Perspectives on the role of the speech and language therapist in palliative care: An international survey.

Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα

Central Artery Perforator Propeller Flap For Nasal And Medial Canthal Defects

Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 1 ώρα

Pharmacogenetics of tyrosine kinase inhibitors in gastrointestinal stromal tumor and chronic myeloid leukemia.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

*Pharmacogenetics of tyrosine kinase inhibitors in gastrointestinal stromal tumor and chronic myeloid leukemia.* Expert Opin Drug Metab Toxicol. 2016 May 5; Authors: Ravegnini G, Sammarini G, Angelini S, Hrelia P Abstract INTRODUCTION: Gastrointestinal stromal tumors (GIST) and chronic myeloid leukemia (CML) are two tumor types deeply different from each other. Despite the differences, these disorders share treatment with tyrosine kinase inhibitor imatinib. Despite the success of imatinib, the response rates vary among different individuals and pharmacogenetics may play an import... περισσότερα »

Effect of personal music system use on sacculocollic reflex assessed by cervical vestibular-evoked myogenic potential: A preliminary investigation.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

[image: http:--http://ift.tt/1WcjJuW] Related Articles *Effect of personal music system use on sacculocollic reflex assessed by cervical vestibular-evoked myogenic potential: A preliminary investigation.* Noise Health. 2016 Mar-Apr;18(81):104-12 Authors: Singh NK, Sasidharan CS Abstract Listening to music through a portable personal music system (PMS) is a growing trend, especially among the youth. The preferred listening level in such kinds of PMS has been reported to cross the safe levels and its impact on the auditory system was demonstrated in several previous investigations. ... περισσότερα »

Developing an assessment approach for perceptual changes to tinnitus sound characteristics for adult cochlear implant recipients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

Oxidative stress biomarkers and otoacoustic emissions in humans exposed to styrene and noise.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

A practical guide to cochlear implantation in adults with long durations of monaural sound deprivation.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

Book Review.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

*Book Review.* Int J Audiol. 2016 May 5;:1 Authors: Brennan M PMID: 27146131 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/21Doaiu via IFTTT

A systematic review of techniques and effects of self-help interventions for tinnitus: Application of taxonomies from health psychology.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

Health behavior theories as predictors of hearing-aid uptake and outcomes.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

Developing an assessment approach for perceptual changes to tinnitus sound characteristics for adult cochlear implant recipients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

Oxidative stress biomarkers and otoacoustic emissions in humans exposed to styrene and noise.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

A practical guide to cochlear implantation in adults with long durations of monaural sound deprivation.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

Book Review.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

A systematic review of techniques and effects of self-help interventions for tinnitus: Application of taxonomies from health psychology.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

Health behavior theories as predictors of hearing-aid uptake and outcomes.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

Impact of levonorgestrel-releasing intrauterine system use on the cancer risk of the ovary and fallopian tube.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

*Impact of levonorgestrel-releasing intrauterine system use on the cancer risk of the ovary and fallopian tube.* Acta Oncol. 2016 May 5;:1-4 Authors: Soini T, Hurskainen R, Grénman S, Mäenpää J, Paavonen J, Pukkala E Abstract BACKGROUND: Levonorgestrel-releasing intrauterine system (LNG-IUS) is used for contraception and heavy menstrual bleeding. A long-term hormone therapy can modify the risk of gynecologic cancers. Little is known about the impact of LNG-IUS use on the risk for invasive and borderline ovarian tumor subtypes or for primary fallopian tube carcinoma. We examined th... περισσότερα »

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα

Prognostic significance of prospectively detected bone marrow micrometastases in esophagogastric cancer: 10-year follow-up confirms prognostic significance.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Related Articles *Prognostic significance of prospectively detected bone marrow micrometastases in esophagogastric cancer: 10-year follow-up confirms prognostic significance.* Cancer Med. 2015 Aug;4(8):1281-8 Authors: Ryan P, Furlong H, Murphy CG, O'Sullivan F, Walsh TN, Shanahan F, O'Sullivan GC Abstract We have previously reported that most patients with esophagogastric cancer (EGC) undergoing potentially curative resections have bone marrow micrometastases (BMM). We present 10-year outcome data of patients with EGC whose rib marrow was examined for micrometastases and correla...περισσότερα »

Effect of body mass index on operative outcome after robotic-assisted Ivor-Lewis esophagectomy: retrospective analysis of 129 cases at a single high-volume tertiary care center.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Potential of Baseline Computed Tomography to Predict Long-Term Survival of Patients With Locally Advanced Esophageal Cancer Treated With Preoperative Chemotherapy: A Retrospective Cohort Study.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Simultaneous Resection of Synchronous Esophageal and Gastric Cancers.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Association between Postoperatively Developed Atrial Fibrillation and Long-Term Mortality after Esophagectomy in Esophageal Cancer Patients: An Observational Study.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Gastroscopic removal of a giant fibrovascular polyp from the esophagus.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Patient features predicting long-term survival and health-related quality of life after radical surgery for non-small cell lung cancer.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

High expression of cyclooxygenase 2 is an indicator of prognosis for patients with esophageal squamous cell carcinoma after Ivor Lewis esophagectomy.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Cost-effectiveness of neoadjuvant concurrent chemoradiotherapy versus esophagectomy for locally advanced esophageal squamous cell carcinoma: A population-based matched case-control study.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Determination of radiotherapeutic target zones for thoracic esophageal squamous cell cancer with lower cervical lymph node metastasis according to CT-images.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

The epithelial-mesenchymal transition phenotype of metastatic lymph nodes impacts the prognosis of esophageal squamous cell carcinoma patients.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

A Dirichlet process mixture model for automatic (18)F-FDG PET image segmentation: Validation study on phantoms and on lung and esophageal lesions.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Spirometric Lung Age Predicts Postoperative Pneumonia After Esophagectomy.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Oesophageal signet ring cell carcinoma as complication of gastro-oesophageal reflux disease.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Related Articles *Oesophageal signet ring cell carcinoma as complication of gastro-oesophageal reflux disease.* Aliment Pharmacol Ther. 2015 Nov;42(10):1222-31 Authors: Turner KO, Genta RM, Sonnenberg A Abstract BACKGROUND: Signet ring cell carcinoma occurs as a histological variant of oesophageal adenocarcinoma. AIM: In a cross-sectional study, to pursue the hypothesis that oesophageal signet ring cell cancers constitute a complication of gastro-oesophageal reflux disease. METHODS: In a large national database of histopathology records, we accumulated 91 802 patients with Barret... περισσότερα »

The Durability of Endoscopic Therapy for Treatment of Barrett's Metaplasia, Dysplasia, and Mucosal Cancer After Nissen Fundoplication.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Related Articles *The Durability of Endoscopic Therapy for Treatment of Barrett's Metaplasia, Dysplasia, and Mucosal Cancer After Nissen Fundoplication.* J Gastrointest Surg. 2015 May;19(5):799-805 Authors: Johnson CS, Louie BE, Wille A, Dunst CM, Worrell SG, DeMeester SR, Reynolds J, Dixon J, Lipham JC, Lada M, Peters JH, Watson TJ, Farivar AS, Aye RW Abstract INTRODUCTION: Radiofrequency ablation (RFA) ± endoscopic resection (EMR) is an established treatment strategy for neoplastic Barrett's and intramucosal cancer. Most patients are managed with proton pump inhibitors. The in... περισσότερα »

High-throughput endogenous measurement of S-nitrosylation in Alzheimer's disease using oxidized cysteine-selective cPILOT

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα

[image: GA?id=C6AN00417B] *Analyst*, 2016, Advance Article *DOI*: 10.1039/C6AN00417B, Paper Liqing Gu, Rena A. S. Robinson Combined precursor isotopic labeling and isobaric tagging (cPILOT) technique enables enhanced multiplexing quantification of S-nitrosylation in biological tissues from animal models of disease. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/26Zi3J8 via IFTTT

Pharmaceutical Crystallization with Nanocellulose Organogels

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα

[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC03088B, Communication Celia Ruiz-Palomero, Stuart R. Kennedy, Maria Laura Soriano, Christopher David Jones, Miguel Valcarcel , Jonathan W Steed Carboxylated nanocellulose forms organogels at 0.3 wt% in the presence of a cationic surfactant. The resulting gels can be used as novel crystallization media for pharmaceutical solid form control, resulting... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1YconXS via IFTTT

Percutaneous microwave ablation of thyroid nodules: effects on thyroid function and antibodies.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

Related Articles *Percutaneous microwave ablation of thyroid nodules: effects on thyroid function and antibodies.* Int J Hyperthermia. 2015;31(5):560-7 Authors: Heck K, Happel C, Grünwald F, Korkusuz H Abstract PURPOSE: Microwave ablation (MWA) is a new minimally invasive method for thermal ablation of benign thyroid nodules with promising results. The aim of this study was to investigate whether MWA has an impact on thyroid function. MATERIALS AND METHODS: Thirty patients with a total of 34 benign thyroid nodules underwent MWA between January 2013 and July 2014. Serum levels of ... περισσότερα »

Multicentric occurrence of multiple papillary thyroid carcinomas--HUMARA and BRAF mutation analysis.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

Related Articles *Multicentric occurrence of multiple papillary thyroid carcinomas--HUMARA and BRAF mutation analysis.* Cancer Med. 2015 Aug;4(8):1272-80 Authors: Nakazawa T, Kondo T, Tahara I, Kasai K, Inoue T, Oishi N, Mochizuki K, Kubota T, Katoh R Abstract Papillary thyroid carcinomas (PTCs) occasionally form multiple tumor foci in different sites of the same thyroid gland. However, it is controversial whether discrete nodules of PTC arise independently (multicentric occurrence) or are seeded from a single tumor via lymphatic channels (intraglandular metastasis). In order to... περισσότερα »

Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 1 ώρα

Related Articles *Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons.* Cereb Cortex. 2015 Sep;25(9):2370-82 Authors: Tivodar S, Kalemaki K, Kounoupa Z, Vidaki M, Theodorakis K, Denaxa M, Kessaris N, de Curtis I, Pachnis V, Karagogeos D Abstract Cortical interneurons are characterized by extraordinary functional and morphological diversity. Although tremendous progress has been made in uncovering molecular and cellular mechanisms implicated in interneuron generation and function, several questions still remain open. Rho-GTPases have been... περισσότερα »

Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

Related Articles *Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study.* Endoscopy. 2015 Aug;47(8):669-74 Authors: Sinh P, Anaparthy R, Young PE, Gaddam S, Thota P, Balasubramanian G, Singh M, Higbee AD, Wani S, Gupta N, Rastogi A, Mathur SC, Bansal A, Horwhat JD, Cash BD, Falk GW, Lieberman DA, Vargo JJ, Sampliner RE, Sharma P Abstract BACKGROUND AND STUDY AIM: Data are limited on the natural history of patients with Barrett's esophagus with a diagnosis of "indefinite for dysplasia" (IND). The aims of thi... περισσότερα »

PDQ Cancer Information Summaries

Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα

*PDQ Cancer Information Summaries* Book. 2002 Authors: Abstract This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of unusual cancers of childhood. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions. This summary is reviewed regularly and updated as necessary by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of the National Ca...περισσότερα »

Percutaneous microwave ablation of thyroid nodules: effects on thyroid function and antibodies.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 1 ώρα

Multicentric occurrence of multiple papillary thyroid carcinomas--HUMARA and BRAF mutation analysis.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 1 ώρα

Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 1 ώρα

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 1 ώρα

Valproate ameliorates nitroglycerin-induced migraine in trigeminal nucleus caudalis in rats through inhibition of NF-кB

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

As a complex nervous system disease, migraine causes severe healthy and social issues worldwide. Valproate (VPA) is a widely used treatment agent against seizures and bipolar disorder, and its function to alle... from Cephalalgia via xlomafota13 on Inoreader http://ift.tt/1WcjJv1 via IFTTT

[Transthoracic myotomy of a case of giant megaesophagus in Mali hospital].

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

[image: http:--http://ift.tt/1MOzwGw] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *[Transthoracic myotomy of a case of giant megaesophagus in Mali hospital].* Pan Afr Med J. 2015;21:239 Authors: Togo S, Abdoulaye OM, Xing L, Sadio Y PMID: 26523179 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1rxUNBM via IFTTT

Randomised clinical trial: transoral incisionless fundoplication vs. sham intervention to control chronic GERD.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Oesophageal signet ring cell carcinoma as complication of gastro-oesophageal reflux disease.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Delayed hypersensitivity reaction after cervical disc replacement: a case report.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Gastroesophageal reflux and lung disease.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Formaldehyde Induces Rho-associated Kinase Activity to Evoke Airway Hyperresponsiveness.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Speech and Language

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

19 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *speech and language* These pubmed results were generated on 2016/05/06 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Speech via a.lsfakia on Inoreader http://ift.tt/1YcuV8L via IFTTT

More art than science: impedance analysis prone to interpretation error.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Severity of nocturnal hypoxia and daytime hypercapnia predict CPAP failure in patients with COPD and obstructive sleep apnea overlap syndrome

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

[image: sleep3037-fig-0001.sml] • Daytime hypercapnia and nocturnal hypoxia are independent predictors of early continuous positive airway pressure (CPAP) failure in patients with the obstructive sleep apnea-continuous positive airway pressure overlap syndrome• An increase of CT90% by 1% (ie, prolongation of time with SpO2 <90% by 1% of total sleep time) increases the likelihood of CPAP failure by ~6%• Bilevel positive airway pressure (BiPAP) therapy effectively alleviates hypercapnia in patients with primary CPAP failure• To increase sleep laboratory personnel alertness towards th...περισσότερα »

Sinonasal Malignancy: What to do with an Unexpected Pathology Result?

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Publication date: Available online 4 May 2016 *Source:*American Journal of Otolaryngology Author(s): Michael B. Hall, Marc R. Rosen, Kurren Gill, Gurston G. Nyquist BackgroundEndoscopic sinus surgery has become the mainstay in surgical treatment of sinusitis and nasal polyps. While rare, diagnostic discrepancies or pathological contamination during routine specimen analysis has been described. Thus, an accurate diagnosis and indication for surgery are mandatory before proceeding with surgical intervention.MethodsWe present the case of a 40-year-old female patient who underwent endos...περισσότερα »

The physiologic role of corticosteroids in Ménière's disease

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Publication date: Available online 4 May 2016 *Source:*American Journal of Otolaryngology Author(s): Zachary Farhood, Paul R. Lambert Multiple options exist to manage Ménière's disease (MD), ranging from dietary modifications to ablative surgery. Corticosteroids (CS) have long been used to manage MD, but their exact mechanism for disease alleviation is relatively uncertain. Glucocorticoid receptors have been shown to exist in the human inner ear and several studies propose influence mechanisms of blood flow, fluid regulation, and ion regulation, with recent evidence describing the l... περισσότερα »

How, When, And From Whom Neck Dissection Operative Technique Is Learned: An International Survey on Neck Dissection Education Among Head and Neck Oncologic Surgeons

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Publication date: Available online 4 May 2016 *Source:*American Journal of Otolaryngology Author(s): Shirin Hemmat, Steven J. Wang, William R. Ryan BackgroundThere is a paucity of evidence on how neck dissection (ND) technique is best learned.MethodsOnline survey of the American Head and Neck Society (AHNS).Results283 of the 1010 (28%) AHNS surgeon members completed the survey.Most respondents had 3–4 mentors [n=157 (55.5%)] that they felt were most influential their ND technique. 134 (47.3% of surgeons who completed a fellowship) felt that fellowship training had the most impact on... περισσότερα »

Perspectives on the role of the speech and language therapist in palliative care: An international survey.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Have artificial neural networks met expectations in drug discovery as implemented in QSAR framework?

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

*Have artificial neural networks met expectations in drug discovery as implemented in QSAR framework?* Expert Opin Drug Discov. 2016 May 5; Authors: Dobchev DA, Karelson M Abstract INTRODUCTION: Artificial neural networks (ANNs) are highly adaptive nonlinear optimization algorithms that have been applied in many diverse scientific endeavors, ranging from economics, engineering, physics, and chemistry to medical science. Notably, in the past two decades, ANNs have been used widely in the process of drug discovery. Areas Covered: In this review, the authors discuss advantages and d...περισσότερα »

Comparison of self and proxy ratings for voice handicap index and motor-related quality-of-life of individuals with Parkinson's disease.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα

Gastroesophageal reflux and lung disease.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα

Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα

More art than science: impedance analysis prone to interpretation error.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα

Perspectives on the role of the speech and language therapist in palliative care: An international survey.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα

Clarifying the best interests standard: the elaborative and enumerative strategies in public policy-making.

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

Clarifying the best interests standard: the elaborative and enumerative strategies in public policy-making. J Med Ethics. 2016 May 4; Authors: Lim CM, Dunn MC, Chin JJ Abstract One recurring criticism of the best interests standard concerns its vagueness, and thus the inadequate guidance it offers to care providers. The lack of an agreed definition of […]

Smoke and mirrors: unanswered questions and misleading statements obscure the truth about organ sources in China.

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

Smoke and mirrors: unanswered questions and misleading statements obscure the truth about organ sources in China. J Med Ethics. 2016 May 4; Authors: Rogers WA, Trey T, Fiatarone Singh M, Bridgett M, Bramstedt KA, Lavee J Abstract This response refutes the claim made in a recent article that organs for transplantation in China will no […]

Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma.

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

Related Articles Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma. N Engl J Med. 2016 Apr 28;374(17):1621-34 Authors: Moreau P, Masszi T, Grzasko N, Bahlis NJ, Hansson M, Pour L, Sandhu I, Ganly P, Baker BW, Jackson SR, Stoppa AM, Simpson DR, Gimsing P, Palumbo A, Garderet L, Cavo M, Kumar S, Touzeau C, Buadi […]

Depression, Social Support, and Mental Health: A Longitudinal Mediation Analysis in African American Custodial Grandmothers.

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

Related Articles Depression, Social Support, and Mental Health: A Longitudinal Mediation Analysis in African American Custodial Grandmothers. Int J Aging Hum Dev. 2016 Mar;82(2-3):166-87 Authors: Whitley DM, Kelley SJ, Lamis DA Abstract Custodial grandparents raising grandchildren experience intense levels of stress that can lead to depression and other forms of psychological distress. Drawing on a […]

Conflict of Interest Guidelines of the Japanese Society of Psychiatry and Neurology: Current Status and Considerations in the Area of Psychiatry.

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

Related Articles [Conflict of Interest Guidelines of the Japanese Society of Psychiatry and Neurology: Current Status and Considerations in the Area of Psychiatry]. Seishin Shinkeigaku Zasshi. 2015;117(9):796-801 Authors: Miyaoka H, Kurihara C Abstract In 2011, the Japanese Society of Psychiatry and Neurology released the Guidelines on Conflict of Interest(COI) in Clinical Research and detailed regulations. […]

A review of patients with advanced cervical cancer presenting to palliative care services at Queen Elizabeth Central Hospital in Blantyre, Malawi.

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

Related Articles A review of patients with advanced cervical cancer presenting to palliative care services at Queen Elizabeth Central Hospital in Blantyre, Malawi. Malawi Med J. 2015 Sep;27(3):93-5 Authors: Bates MJ, Mijoya A Abstract BACKGROUND: Cervical cancer is the commonest cancer affecting women in Malawi, which has the highest rate of this disease in the […]

A suitable palpation technique allows to identify skin lipohypertrophic lesions in insulin-treated people with diabetes

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

Lipohypertrophy (LH) is a major complication of subcutaneous insulin treatment brought about by multiple overlapping injections and/or needle reuse. It is responsible for unacceptable glucose oscillations due … from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/26ZoL1L via IFTTT

Erratum to: Epidemiology of dementia in Central Africa (EPIDEMCA): protocol for a multicentre population-based study in rural and urban areas of the Central African Republic and the Republic of Congo

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OgBZLX via IFTTT

Pediatric Epidemic of Salmonella enterica Serovar Typhimurium in the Area of L’Aquila, Italy, Four Years after a Catastrophic Earthquake

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

Background: A Salmonella enterica epidemic occurred in children of the area of L’Aquila (Central Italy, Abruzzo region) between June 2013 and October 2014, four years after the catastrophic earthquake of 6 April 2009. Methods: Clinical and laboratory data were collected from hospitalized and ambulatory children. Routine investigations for Salmonella infection were carried out on numerous […]

Lung Cancer Mortality and Topography: A Xuanwei Case Study

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα

The epidemic of lung cancer in Xuanwei City, China, remains serious despite the reduction of the risk of indoor air pollution through citywide stove improvement. The main objective of this study was to characterize the influences of topography on the spatiotemporal variations of lung cancer mortality in Xuanwei during 1990–2013. Using the spatially empirical Bayes […]

Time-frequency analysis of the EEG mu rhythm as a measure of sensorimotor integration in the latter stages of swallowing

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα

The ability to swallow is vital to human survival. An efficient swallow requires precise neuromuscular control over three distinct phases (Ertekin and Aydogdu, 2003; Hamdy et al., 1999; Langmore, 2001; Mosier and Bereznaya, 2001; Furlong et al., 2003; Logemann, 1998; Shaw and Martino 2013). During the oral phase, food and/or liquid are transformed into a bolus that subsequently is propelled posteriorly toward the pharynx (Logemann, 1998). Once the bolus reaches the anterior faucial pillars, the pharyngeal phase of the swallow triggers to maneuver the bolus through the pharynx while ... περισσότερα »

Assessment of the upper motor neurone in amyotrophic lateral sclerosis

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα

The term amyotrophic lateral sclerosis was first coined by Charcot, who postulated the primacy of the upper motor neuron in ALS pathogenesis (Charcot et al., 1869) with loss of Betz cells in the motor cortex being a well-recognized pathological feature (Kaufmann et al., 2004). The clinical diagnosis of classical amyotrophic lateral sclerosis (ALS) is determined by identification of progressive dysfunction of both cortical (‘upper’) and spinal (‘lower’) motor neurons across multiple body regions (chiefly limb and bulbar), much of which was encapsulated by the El Escorial criteria (Br... περισσότερα »

Voluntary Physical Activity Abolishes the Proliferative Tumor Growth Microenvironment Created by Adipose Tissue in Animals Fed a High Fat Diet

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα

The molecular mechanisms behind the obesity-breast cancer association may be regulated via adipokine secretion by white adipose tissue. Specifically, adiponectin (ADIPO) and leptin (LEP) are altered with adiposity and exert antagonistic effects on cancer cell proliferation. We set out to determine whether altering adiposity in-vivo via high fat diet (HFD) feeding changed the tumor growth supporting nature of adipose tissue and if voluntary physical activity (VPA) could ameliorate these HFD-dependent effects. We show that conditioned media (CM) created from the adipose tissue of HFD... περισσότερα »

No effect of elevated operating lung volumes on airway function during variable workrate exercise in asthmatic humans

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα

In asthmatic adults, airway caliber fluctuates during variable intensity exercise such that bronchodilation (BD) occurs with increased workrate whereas bronchoconstriction (BC) occurs with decreased workrate. We hypothesized that increased lung mechanical stretch would prevent BC during such variable workrate exercise. Ten asthmatic and ten non-asthmatic subjects completed two exercise trials on a cycle ergometer. Both trials included a 28-minute exercise bout consisting of alternating four minute periods at workloads equal to 40 (Low) and 70% (High) peak power output. During one ...περισσότερα »

Effect of eccentric exercise with reduced muscle glycogen on plasma interleukin-6 and neuromuscular responses of m. quadriceps femoris

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα

Eccentric exercise can result in muscle damage and interleukin-6 (IL-6) secretion. Glycogen availability is a potent stimulator of IL-6 secretion. We examined effects of eccentric exercise in a low glycogen state on neuromuscular function and plasma IL-6 secretion. Twelve active males (23 ± 4 years, 179 ± 5 cm, 77 ± 10 kg) completed two downhill treadmill runs (gradient, -12%, 5x8 min; speed, 12.1 ± 1.1 km•h-1) with normal (NG) and reduced muscle glycogen (RG) in randomized order and at least six weeks apart. Muscle glycogen was reduced using an established cycling protocol until ...περισσότερα »

Perfusion-related stimuli for compensatory lung growth following pneumonectomy

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα

Following pneumonectomy (PNX), two separate mechanical forces act on the remaining lung: parenchymal stress caused by lung expansion, and microvascular distension and shear caused by increased perfusion. We previously showed that parenchymal stress and strain explains approximately one-half of overall compensation; the remainder was presumptively attributed to perfusion-related factors. In this study we directly tested the hypothesis that perturbation of regional pulmonary perfusion modulates post-PNX lung growth. Adult canines underwent banding of the pulmonary artery (PAB) to th...περισσότερα »

The effect of aging and exercise on the tendon

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα

Here we review the literature on how tendons respond and adapt to ageing and exercise. With respect to aging, there are considerable changes early in life, but this seems to be maturation rather than aging per se. In vitro data indicate that aging is associated with a decreased potential for cell proliferation and a reduction in the number of stem/progenitor like cells. Further, there is persuasive evidence that turnover in the core of the tendon after maturity is very slow or absent. Tendon fibril diameter, collagen content, and whole tendon size appear to be largely unchanged wit... περισσότερα »

Effects of commonly used inotropes on myocardial function and oxygen consumption under constant ventricular loading conditions

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα

Inotropic medications are routinely used to increase cardiac output and arterial blood pressure during critical illness. However, few comparative data exist between these medications, particularly independent of their effects on venous capacitance and systemic vascular resistance. We hypothesized that an isolated working heart model which maintained constant left atrial pressure and aortic blood pressure could identify load-independent differences between inotropic medications. In an isolated heart preparation, the aorta and left atrium of Sprague Dawley rats were cannulated and p...περισσότερα »

Cell origin in the macula flava of the human newborn vocal fold

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Research Articles K Sato, S Chitose, T Kurita, H Umeno The Journal of Laryngology & Otology,FirstView Article(s), 6 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #ORL via xlomafota13 on Inoreader http://ift.tt/1O2eGuu via IFTTT

Association of genetic polymorphism and external apical root resorption: A systematic review

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα

The Angle Orthodontist, Ahead of Print. from #Dental via xlomafota13 on Inoreader http://ift.tt/1WccdQO via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Severity of nocturnal hypoxia and daytime hypercapnia predict CPAP failure in patients with COPD and obstructive sleep apnea overlap syndrome

Alexandros G. SfakianakisστοΥπνική Άπνοια και Διαταραχές ΎπνουΠριν από 1 ώρα

Association of genetic polymorphism and external apical root resorption: A systematic review

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα

The Angle Orthodontist, Ahead of Print. from #Dental via xlomafota13 on Inoreader http://ift.tt/1WccdQO via IFTTT

One-year results of maxillary overdentures supported by 2 titanium–zirconium implants – implant survival rates and radiographic outcomes

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα

Abstract Objective To assess implant survival rates and peri-implant bone loss of 2 titanium–zirconium implants supporting maxillary overdentures at 1 year of loading. Material and Methods Twenty maxillary edentulous patients (5 women and 15 men) being dissatisfied with their complete dentures were included. In total, 40 diameter-reduced titanium–zirconium implants were placed in the anterior maxilla. Local guided bone regeneration (GBR) was allowed if the treatment did not compromise implant stability. Following 3 to 5 months of healing, implant-supported overdentures were inserte...περισσότερα »

Accuracy of digital impressions of multiple dental implants: an in vitro study

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα

Abstract Introduction Studies demonstrated that the accuracy of intra-oral scanners can be compared with conventional impressions for most indications. However, little is known about their applicability to take impressions of multiple implants. Aim The aim of this study was to evaluate the accuracy of four intra-oral scanners when applied for implant impressions in the edentulous jaw. Material and methods An acrylic mandibular cast containing six external connection implants (region 36, 34, 32, 42, 44 and 46) with PEEK scanbodies was scanned using four intra-oral scanners: the Lava... περισσότερα »

Simple method of securing an airway while accessing a bleeding tracheostomy site when nasal or oral endotracheal intubation is not feasible

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα

Tracheostomies are often used in operations for cancer of the head and neck,1–3 and bleeding is a recognised complication,3,4 in about 5% of patients.5 To control this postoperatively, it is necessary to directly see and gain access to the site of the haemorrhage, but the tracheostomy tube is often in the way. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1STfrD8 via IFTTT

Single-centre experience of primary cutaneous Merkel cell carcinoma of the head and neck between 1996 and 2014

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα

We retrospectively reviewed the management at our centre of 25 patients with Merkel cell carcinoma (MCC) of the head and neck. We obtained details of the operation, including wide local excision, sentinel lymph node biopsy (SNB), neck dissection, postoperative radiotherapy, and clinical outcomes, from patients’ records. All patients were white, 11 were men and 14 women, mean age at presentation 81 years (range 67-90). At the time of diagnosis, 18 patients had stage I disease, and 7 stage II disease. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1ZlpBQE via IFTTT

Severity of nocturnal hypoxia and daytime hypercapnia predict CPAP failure in patients with COPD and obstructive sleep apnea overlap syndrome

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Sinonasal Malignancy: What to do with an Unexpected Pathology Result?

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

The physiologic role of corticosteroids in Ménière's disease

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

How, When, And From Whom Neck Dissection Operative Technique Is Learned: An International Survey on Neck Dissection Education Among Head and Neck Oncologic Surgeons

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Αρχειοθήκη ιστολογίου

Παρασκευή 6 Μαΐου 2016

OtoRhinoLaryngology & Medicine,New Articles,May 6th,2016,a

Upper Respiratory Tract Infections

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