Temporal patterns of 18F-fluorodeoxyglucose positron emission tomography/computed tomography sinonasal uptake after treatment of sinonasal malignancy
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 λεπτό
Background Current guidelines have identified 10 to 12 weeks posttreatment as the ideal time-point for improved diagnostic accuracy of positron emission tomography/computed tomography (PET/CT) for deep tissue sites of the head and neck. After treatment, the sinonasal skull base is predisposed to prolonged inflammation that may render this time-point inappropriate for initial posttreatment imaging surveillance […]
Response to: The “RACE” national database for recurrent acute rhinosinusitis may need a relook
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 λεπτό
from Allergy via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29RavAq via IFTTT
Endoscopic sinus surgery improves cognitive dysfunction in patients with chronic rhinosinusitis
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 λεπτό
Background Patients with chronic rhinosinusitis (CRS) have been found to have cognitive deficit, as identified using the Cognitive Failures Questionnaire (CFQ), but the exact etiology of cognitive decline is unknown. In this study we aimed to determine whether improvement in concomitant inflammation and disease burden in CRS, using endoscopic sinus surgery (ESS), improves cognitive deficit. […]
Temporal patterns of 18F-fluorodeoxyglucose positron emission tomography/computed tomography sinonasal uptake after treatment of sinonasal malignancy
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
[image: cover.gif?v=1&s=ed4df7da091ebcd975bf6aad] Background Current guidelines have identified 10 to 12 weeks posttreatment as the ideal time-point for improved diagnostic accuracy of positron emission tomography/computed tomography (PET/CT) for deep tissue sites of the head and neck. After treatment, the sinonasal skull base is predisposed to prolonged inflammation that may render this time-point inappropriate for initial posttreatment imaging surveillance for sinonasal malignancies. The purpose of this study is to evaluate temporal trends in 18F-fluorodeoxyglucose (18FDG) sinon... περισσότερα »
Response to: The “RACE” national database for recurrent acute rhinosinusitis may need a relook
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
[image: cover.gif?v=1&s=ed4df7da091ebcd975bf6aad] http://ift.tt/29RavAq
Endoscopic sinus surgery improves cognitive dysfunction in patients with chronic rhinosinusitis
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
Background Patients with chronic rhinosinusitis (CRS) have been found to have cognitive deficit, as identified using the Cognitive Failures Questionnaire (CFQ), but the exact etiology of cognitive decline is unknown. In this study we aimed to determine whether improvement in concomitant inflammation and disease burden in CRS, using endoscopic sinus surgery (ESS), improves cognitive deficit. We also sought to identify comorbid conditions that effect improvement likelihood. Methods Study participants (n = 247) with and without nasal polyposis (CRSwNP, CRSsNP) were prospectively enrol... περισσότερα »
Clinical impact of strict criteria for selectivity and lateralization in adrenal vein sampling.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*Clinical impact of strict criteria for selectivity and lateralization in adrenal vein sampling.* Hormones (Athens). 2015 Apr;15(2):264-70 Authors: Gasparetto A, Angle JF, Darvishi P, Freeman CW, Norby RG, Carey RM Abstract INTRODUCTION: Selectivity index (SI) and lateralization index (LI) thresholds determine the adequacy of adrenal vein sampling (AVS) and the degree of lateralization. The purpose of this study was investigate the clinical outcome of patients whose adrenal vein sampling was interpreted using “strict criteria” (SC) (SIpre-stimuli≥3, SIpost-stimuli≥5 and LIpre-sti... περισσότερα »
Salivary testosterone responses to a physical and psychological stimulus and subsequent effects on physical performance in healthy adults.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*Salivary testosterone responses to a physical and psychological stimulus and subsequent effects on physical performance in healthy adults.* Hormones (Athens). 2015 Apr;15(2):248-55 Authors: Crewther BT, Kilduff LP, Finn C, Scott P, Cook CJ Abstract OBJECTIVE: To address the rapid influence of testosterone (T) on neuromuscular performance, we compared the T and physical performance responses of adults exposed to a physical and psychological stimulus. DESIGN: A group of healthy men (n=12) and women (n=14) each completed three treatments using a randomised, crossover design: exercise... περισσότερα »
Impacts of Perinatal Dioxin Exposure on Motor Coordination and Higher Cognitive Development in Vietnamese Preschool Children: A Five-Year Follow-Up.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Impacts of Perinatal Dioxin Exposure on Motor Coordination and Higher Cognitive Development in Vietnamese Preschool Children: A Five-Year Follow-Up.* PLoS One. 2016;11(1):e0147655 Authors: Tran NN, Pham TT, Ozawa K, Nishijo M, Nguyen AT, Tran TQ, Hoang LV, Tran AH, Phan VH, Nakai A, Nishino Y, Nishijo H Abstract Dioxin concentrations remain elevated in the environment and in humans residing near former US Air Force bases in South Vietnam. Our previous epidemiological studies showed adver... περισσότερα »
Wellbeing and resilience: mechanisms of transmission of health and risk in parents with complex mental health problems and their offspring--The WARM Study.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Wellbeing and resilience: mechanisms of transmission of health and risk in parents with complex mental health problems and their offspring–The WARM Study.* BMC Psychiatry. 2015;15:310 Authors: Harder S, Davidsen K, MacBeth A, Lange T, Minnis H, Andersen MS, Simonsen E, Lundy JM, Nyström-Hansen M, Trier CH, Røhder K, Gumley A Abstract UNLABELLED: The WARM study is a longitudinal cohort study following infants of mothers with schizophrenia, bipolar disorder, depression and control from pre... περισσότερα »
Brief Measures to Screen for Social Anxiety in Adolescents.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Brief Measures to Screen for Social Anxiety in Adolescents.* J Dev Behav Pediatr. 2015 Oct;36(8):562-8 Authors: Garcia-Lopez LJ, Sáez-Castillo AJ, Beidel D, La Greca AM Abstract OBJECTIVE: Social anxiety disorder (SAD) in adolescents is considerably underdetected and undertreated despite the availability of efficacious treatments. Our main study objective was to examine brief, valid, and reliable screening measures for adolescent social anxiety, and to then conduct diagnostic interviews to evaluate the measures’ ab... περισσότερα »
Reliability of the Size Evaluation Method for Meningiomas: Maximum Diameter, ABC/2 Formula, and Planimetry Method.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*Reliability of the Size Evaluation Method for Meningiomas: Maximum Diameter, ABC/2 Formula, and Planimetry Method.* World Neurosurg. 2016 Jul 2; Authors: Ishi Y, Terasaka S, Yamaguchi S, Yoshida M, Endo S, Kobayashi H, Houkin K Abstract BACKGROUND: To evaluate the accuracy of tumor size by the maximum diameter, ABC/2 formula, and planimetry method using thick and thin slice magnetic resonance imaging (MRI). METHODS: Maximum diameter and tumor volume calculated using the ABC/2 formula (V1) and planimetry method with thick slice (V2) and thin slice (V3) MRI were examined in 83 men... περισσότερα »
A summary of some of the recently published, seminal papers in neuroscience.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*A summary of some of the recently published, seminal papers in neuroscience.* Neurol India. 2016 Jul-Aug;64(4):758-781 Authors: Sridhar K, Paliwal V, Kohat AK, Takkar A, Yadav R, Turel MK, Tripathi M, Das KK, Mehrotra A PMID: 27381125 [PubMed - as supplied by publisher] http://ift.tt/29oqslA
Treatment Algorithm for Intracranial Intrusion Injuries of the Mandibular Condyle.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Treatment Algorithm for Intracranial Intrusion Injuries of the Mandibular Condyle.* J Oral Maxillofac Surg. 2016 Mar;74(3):569-81 Authors: Arya V, Chigurupati R Abstract PURPOSE: Traumatic injuries of the mandible resulting in intrusion of the condyle into the middle cranial fossa are rare and treatment is often based on anecdotal experience. The objective of this study was to develop an algorithm for the management of condylar intrusion injuries by identifying factors that influenced the treatment decision of clo... περισσότερα »
Videoassisted anterior surgical approaches to the craniocervical junction: rationale and clinical results.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *Videoassisted anterior surgical approaches to the craniocervical junction: rationale and clinical results.* Eur Spine J. 2015 Dec;24(12):2713-23 Authors: Visocchi M, Di Martino A, Maugeri R, González Valcárcel I, Grasso V, Paludetti G Abstract PURPOSE: In this narrative review, we aim to give an update on the anatomic fundamentals of endoscopic assisted surgery to the craniocervical junction (transnasal, transoral and transcervical), and to report on the available clinical results. METHODS: A non-systematic review... περισσότερα »
Editorial Board.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*Editorial Board.* J Clin Endocrinol Metab. 2016 Jul;101(7):1A Authors: PMID: 27381961 [PubMed - in process] http://ift.tt/29mREvW
Table of Contents.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*Table of Contents.* J Clin Endocrinol Metab. 2016 Jul;101(7):3A-9A Authors: PMID: 27381962 [PubMed - in process] http://ift.tt/29qoYpp
Disorders of Puberty: Take a Good History!
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*Disorders of Puberty: Take a Good History!* J Clin Endocrinol Metab. 2016 Jul;101(7):2643-6 Authors: Witchel SF PMID: 27381960 [PubMed - in process] http://ift.tt/29qphR2
The Model T.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*The Model T.* J Clin Endocrinol Metab. 2016 Jul;101(7):2640-2 Authors: Anawalt BD PMID: 27381959 [PubMed - in process] http://ift.tt/29mRYKX
Resistance to Thyroid Hormone α-Emerging Definition of a Disorder of Thyroid Hormone Action.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*Resistance to Thyroid Hormone α-Emerging Definition of a Disorder of Thyroid Hormone Action.* J Clin Endocrinol Metab. 2016 Jul;101(7):2636-9 Authors: Moran C, Chatterjee K PMID: 27381958 [PubMed - in process] http://ift.tt/29sK2e3
A Reappraisal of Prediabetes.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*A Reappraisal of Prediabetes.* J Clin Endocrinol Metab. 2016 Jul;101(7):2628-35 Authors: Davidson MB, Kahn RA PMID: 27381957 [PubMed - in process] http://ift.tt/29qpuUo
Morphology of mucosa-associated lymphoid tissue in odontocetes.
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
*Morphology of mucosa-associated lymphoid tissue in odontocetes.* Microsc Res Tech. 2016 Jul 6; Authors: Silva FM, Guimarães JP, Vergara-Parente JE, Carvalho VL, Carolina A, Meirelles O, Marmontel M, Oliveira BS, Santos SM, Becegato EZ, Evangelista JS, Miglino MA Abstract This study describes the mucosa-associated lymphoid tissue (MALT) in odontocetes from the Brazilian coast and freshwater systems. Seven species were evaluated and tissue samples were analyzed by light, scanning and transmission electron microscopy, and immunohistochemistry. Laryngeal tonsil was a palpable oval m... περισσότερα »
[Expression and clinical pathological implications of carbonic anhydrase 9 and P glycoprotein in laryngeal squamous cell carcinoma].
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 6 δευτερόλεπτα
Related Articles *[Expression and clinical pathological implications of carbonic anhydrase 9 and P glycoprotein in laryngeal squamous cell carcinoma].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Jan;30(1):42-4 Authors: Chen X, Wang F, Xie F, Dong P, Ying X Abstract OBJECTIVE: To identify the difference of CA IX and P-gp expression level between laryngeal squamous cell carcinoma (LSCC) and benign tissues, evaluate the relationship of these two proteins in LSCC, and their correlation with clinical and pathological features. METHOD: Immunohistochemical detection of CA IX and... περισσότερα »
Resistance to Thyroid Hormone α-Emerging Definition of a Disorder of Thyroid Hormone Action.
*Resistance to Thyroid Hormone α-Emerging Definition of a Disorder of Thyroid Hormone Action.* J Clin Endocrinol Metab. 2016 Jul;101(7):2636-9 Authors: Moran C, Chatterjee K PMID: 27381958 [PubMed - in process] from thyroid via a.lsfakia on Inoreader http://ift.tt/29sK2e3 via IFTTT
Preoperative vocal cord paralysis and its association with malignant thyroid disease and other pathological features.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Preoperative vocal cord paralysis and its association with malignant thyroid disease and other pathological features.* J Otolaryngol Head Neck Surg. 2015;44:35 Authors: Kay-Rivest E, Mitmaker E, Payne RJ, Hier MP, Mlynarek AM, Young J, Forest VI Abstract BACKGROUND: Vocal cord paralysis (VCP) is found in both benign and malignant thyroid disease. This study was performed to determine if the presence of preoperative VCP predicts malignancy. METHODS: A retrospective analysis was performed ... περισσότερα »
Are we really at the dawn of understanding sporadic pediatric thyroid carcinoma?
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Are we really at the dawn of understanding sporadic pediatric thyroid carcinoma?* Endocr Relat Cancer. 2015 Dec;22(6):R311-24 Authors: Cordioli MI, Moraes L, Cury AN, Cerutti JM Abstract Data from the National Cancer Institute and from the literature have disclosed an increasing incidence of thyroid cancer in children, adolescents and adults. Although children and adolescents with thyroid cancer tend to present with more advanced disease than adults, their overall survival rate is excellent; however, there is no ... περισσότερα »
Resistance to Thyroid Hormone α-Emerging Definition of a Disorder of Thyroid Hormone Action.
*Resistance to Thyroid Hormone α-Emerging Definition of a Disorder of Thyroid Hormone Action.* J Clin Endocrinol Metab. 2016 Jul;101(7):2636-9 Authors: Moran C, Chatterjee K PMID: 27381958 [PubMed - in process] from thyroid via a.lsfakia on Inoreader http://ift.tt/29sK2e3 via IFTTT
Adjuvant Radioactive iodine 131 ablation in papillary microcarcinoma of thyroid: Saudi Arabian experience [corrected].
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Adjuvant Radioactive iodine 131 ablation in papillary microcarcinoma of thyroid: Saudi Arabian experience [corrected].* J Otolaryngol Head Neck Surg. 2015;44:51 Authors: Al-Qahtani KH, Al Asiri M, Tunio MA, Aljohani NJ, Bayoumi Y, Fatani H, AlHadab A Abstract BACKGROUND: Papillary Microcarcinoma (PMC) of thyroid is a rare type of differentiated thyroid cancer (DTC), which according to the World Health Organization measures 1.0 cm or less. The gold standard of treatment of PMC is still c... περισσότερα »
[A case of large solitary fibrous tumor originated from the neck].
Related Articles *[A case of large solitary fibrous tumor originated from the neck].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Jan;30(2):153-4 Authors: Luo Q, Zhang S, Zhang Z Abstract Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm that usually develops in the pleura and peritoneum. The head and the neck region is involved in only 6% of the cases. We described a rare case of large SFT originated from the right neck region in a 32-year-old man. Enhanced CT scan revealed two large completely resected masses in the carotid sheath region and the right thyroi... περισσότερα »
Quality of life and cosmetic result of single-port access endoscopic thyroidectomy via axillary approach in patients with papillary thyroid carcinoma
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A systematic review and meta-analysis of the risk of diarrhea associated with vandetanib treatment in carcinoma patients.
*A systematic review and meta-analysis of the risk of diarrhea associated with vandetanib treatment in carcinoma patients.* Onco Targets Ther. 2016;9:3621-31 Authors: Huo Z, Yu S, Hong S, Cao X, Xiu L, Liao Z, Li Y, Xiao H Abstract BACKGROUND AND PURPOSE: Vandetanib is a promising anticancer targeted agent for treating advanced carcinomas, such as non-small-cell lung cancer, small-cell lung cancer, breast cancer, malignant glioma, hepatocellular cancer, and unresectable, locally advanced, or metastatic medullary thyroid cancer. However, diarrhea is a frequently reported adverse ev... περισσότερα »
Endocrine Abnormalities in Aging Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study.
*Endocrine Abnormalities in Aging Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study.* J Clin Oncol. 2016 Jul 5; Authors: Mostoufi-Moab S, Seidel K, Leisenring WM, Armstrong GT, Oeffinger KC, Stovall M, Meacham LR, Green DM, Weathers R, Ginsberg JP, Robison LL, Sklar CA Abstract PURPOSE: The development of endocrinopathies in survivors of childhood cancer as they age remains understudied. We characterized endocrine outcomes in aging survivors from the Childhood Cancer Survivor Study on the basis of therapeutic exposures. PATIENTS AND METHODS: We anal... περισσότερα »
Thyroid dysfunction, either hyper or hypothyroidism, promotes gallstone formation by different mechanisms.
*Thyroid dysfunction, either hyper or hypothyroidism, promotes gallstone formation by different mechanisms.* J Zhejiang Univ Sci B. 2016 Jul;17(7):515-25 Authors: Wang Y, Yu X, Zhao QZ, Zheng S, Qing WJ, Miao CD, Sanjay J Abstract We have investigated comprehensively the effects of thyroid function on gallstone formation in a mouse model. Gonadectomized gallstone-susceptible male C57BL/6 mice were randomly distributed into three groups each of which received an intervention to induce hyperthyroidism, hypothyroidism, or euthyroidism. After 5 weeks of feeding a lithogenic diet of 15... περισσότερα »
[A case of large solitary fibrous tumor originated from the neck].
Related Articles *[A case of large solitary fibrous tumor originated from the neck].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Jan;30(2):153-4 Authors: Luo Q, Zhang S, Zhang Z Abstract Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm that usually develops in the pleura and peritoneum. The head and the neck region is involved in only 6% of the cases. We described a rare case of large SFT originated from the right neck region in a 32-year-old man. Enhanced CT scan revealed two large completely resected masses in the carotid sheath region and the right thyroi... περισσότερα »
[Value of thyroid imaging reporting and data system and shear wave elastography for diagnosis of thyroid microcarcinoma].
Related Articles *[Value of thyroid imaging reporting and data system and shear wave elastography for diagnosis of thyroid microcarcinoma].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Jan;30(2):118-22 Authors: Lu X, Zhang Y, Liu Y, Zhang N, Zhang C Abstract OBJECTIVE: To investigate the value of each single and combined applications of ultrasound thyroid imaging reporting and data system (TI-RADS), ultrasonic shear wave elastography in the diagnosis of thyroid microcarcinoma (TMC). METHOD: 323 patients with thyroid tiny nodules confirmed by surgery and pathology were an... περισσότερα »
MED27 promotes melanoma growth by targeting AKT/MAPK and NF-κB/iNOS signaling pathways.
Related Articles *MED27 promotes melanoma growth by targeting AKT/MAPK and NF-κB/iNOS signaling pathways.* Cancer Lett. 2016 Apr 1;373(1):77-87 Authors: Tang R, Xu X, Yang W, Yu W, Hou S, Xuan Y, Tang Z, Zhao S, Chen Y, Xiao X, Huang W, Guo W, Li M, Deng W Abstract The inhibitors of BRAF and MEK targeting MAPK signaling pathway provide a comparatively effective therapeutic strategy for melanoma caused by BRAF mutation. However, melanoma, especially metastatic melanoma, has become one of the most threatening malignancies. Thus, the identification of exact molecular mechanisms and... περισσότερα »
Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline.
Related Articles *Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline.* J Clin Endocrinol Metab. 2016 Feb;101(2):364-89 Authors: Bornstein SR, Allolio B, Arlt W, Barthel A, Don-Wauchope A, Hammer GD, Husebye ES, Merke DP, Murad MH, Stratakis CA, Torpy DJ Abstract OBJECTIVE: This clinical practice guideline addresses the diagnosis and treatment of primary adrenal insufficiency. PARTICIPANTS: The Task Force included a chair, selected by The Clinical Guidelines Subcommittee of the Endocrine Society, eight additional clinicians e... περισσότερα »
Pathobiology of MicroRNAs and Their Emerging Role in Thyroid Fine-Needle Aspiration.
Related Articles *Pathobiology of MicroRNAs and Their Emerging Role in Thyroid Fine-Needle Aspiration.* Acta Cytol. 2015;59(6):435-44 Authors: Ludvíková M, Kalfeřt D, Kholová I Abstract OBJECTIVE: MicroRNAs (miRs) are noncoding, single-stranded regulatory RNA molecules involved in the posttranscriptional regulation of gene expression. They control the development and maintenance of the diverse cellular processes including proliferation, differentiation, motility and apoptosis. Expression of miRs is tissue-specific and each alteration of the tissue miR profile is associated with ... περισσότερα »
[Evaluation of wall configuration ultrasonogrophicin diagnosis of thyroid small nodules using binary logistic regression].
Related Articles *[Evaluation of wall configuration ultrasonogrophicin diagnosis of thyroid small nodules using binary logistic regression].* Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Oct;50(10):818-22 Authors: Fu Q, Wu P, Ding Y Abstract OBJECTIVE: To screen out the sonogram features for the differential diagnosis of benign and malignant thyroid small nodules (≤ 1.0 cm) by Logistics regression analysis, to establish the binary Logistic regression model of sonogram features as independent variable and investigate the value of wall configuration of ultrasonogrophic nodul... περισσότερα »
[Thyroid hyaliniziing trabecular adenoma with calcification: a case report].
Related Articles *[Thyroid hyaliniziing trabecular adenoma with calcification: a case report].* Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Sep;50(9):780 Authors: Wang C, She C PMID: 26696357 [PubMed - indexed for MEDLINE] http://ift.tt/29BgPPZ
Local molecular analysis of indeterminate thyroid nodules.
Related Articles *Local molecular analysis of indeterminate thyroid nodules.* J Otolaryngol Head Neck Surg. 2015;44:52 Authors: Gill MS, Nayan S, Kocovski L, Cutz JC, Archibald SD, Jackson BS, Young JE, Gupta MK Abstract BACKGROUND: Thyroid nodules are common but only a minority are malignant. Molecular testing can assist in helping determine whether indeterminate nodules are suspicious for malignancy or benign. The objective of the study was to determine if the analysis of mutations (BRAF, NRAS, KRAS and HRAS) using readily available molecular techniques can help better classify... περισσότερα »
Radiofrequency versus Ethanol Ablation for Treating Predominantly Cystic Thyroid Nodules: A Randomized Clinical Trial.
Related Articles *Radiofrequency versus Ethanol Ablation for Treating Predominantly Cystic Thyroid Nodules: A Randomized Clinical Trial.* Korean J Radiol. 2015 Nov-Dec;16(6):1332-40 Authors: Baek JH, Ha EJ, Choi YJ, Sung JY, Kim JK, Shong YK Abstract OBJECTIVE: To compare single-session radiofrequency ablation (RFA) and ethanol ablation (EA) for treating predominantly cystic thyroid nodules (PCTNs). MATERIALS AND METHODS: This single-blind, randomized trial was approved by the Institutional Review Board of two centers and informed consent was obtained from all patients before enr... περισσότερα »
The Type of Breast Reconstruction May Not Influence Patient Satisfaction in the Chinese Population: A Single Institutional Experience.
Related Articles *The Type of Breast Reconstruction May Not Influence Patient Satisfaction in the Chinese Population: A Single Institutional Experience.* PLoS One. 2015;10(11):e0142900 Authors: Yang B, Li L, Yan W, Chen J, Chen Y, Hu Z, Liu G, Shen Z, Shao Z, Wu J Abstract BACKGROUND: The goal of this study was to evaluate patient satisfaction with four common types of breast reconstruction performed at our institution: latissimus dorsi myocutaneous (LDM) flap reconstruction with or without implants, pedicled transverse rectus abdominis musculocutaneous (TRAM) flap reconstructio... περισσότερα »
Surgeon-performed ultrasound guided fine-needle aspirate biopsy with report of learning curve; a consecutive case-series study.
Related Articles *Surgeon-performed ultrasound guided fine-needle aspirate biopsy with report of learning curve; a consecutive case-series study.* J Otolaryngol Head Neck Surg. 2015;44:42 Authors: Fernandes VT, De Santis RJ, Enepekides DJ, Higgins KM Abstract BACKGROUND: Fine-needle aspiration biopsy has become the standard of care for the evaluation of thyroid nodules. More recently, the use of ultrasound guided fine-needle aspiration biopsy (UG-FNAB) has improved adequacy of sampling. Now there has been improved access to UG-FNAB as ultrasound technology has become more accessi... περισσότερα »
Identification of insertions in PTEN and TP53 in anaplastic thyroid carcinoma with angiogenic brain metastasis.
Related Articles *Identification of insertions in PTEN and TP53 in anaplastic thyroid carcinoma with angiogenic brain metastasis.* Endocr Relat Cancer. 2015 Dec;22(6):L23-8 Authors: Sadow PM, Dias-Santagata D, Zheng Z, Lin DT, Le LP, Nucera C PMID: 26472209 [PubMed - indexed for MEDLINE] http://ift.tt/29uBu5r
Preoperative vocal cord paralysis and its association with malignant thyroid disease and other pathological features.
Related Articles *Preoperative vocal cord paralysis and its association with malignant thyroid disease and other pathological features.* J Otolaryngol Head Neck Surg. 2015;44:35 Authors: Kay-Rivest E, Mitmaker E, Payne RJ, Hier MP, Mlynarek AM, Young J, Forest VI Abstract BACKGROUND: Vocal cord paralysis (VCP) is found in both benign and malignant thyroid disease. This study was performed to determine if the presence of preoperative VCP predicts malignancy. METHODS: A retrospective analysis was performed on a cohort of 1923 consecutive patients undergoing thyroid surgery. The inc... περισσότερα »
[Ultrasound guided percutaneous microwave ablation in the treatment of recurrent thyroid nodules].
Related Articles *[Ultrasound guided percutaneous microwave ablation in the treatment of recurrent thyroid nodules].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Apr;29(7):622-4 Authors: Liu Y, Wang W, Wang Y, An L, Shi G, Feng B Abstract OBJECTIVE: To explore the clinical effect of ultrasound guided microwave ablation in the treatment 01 recurrent thyroid nodules. METHOD: Seventy-five cases of recurrent thyroid nodules were treated with ultrasound guided microwave ablation(MWA) under local anesthesia. All the patients underwent biopsy puncture, then the microwave ablatio... περισσότερα »
Cis retinol oxidation regulates photoreceptor access to the retina visual cycle and cone pigment regeneration
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Abstract Chromophore supply by the retinal Müller cells (retina visual cycle) supports the efficient pigment regeneration required for cone photoreceptor function in bright light. Surprisingly, a large fraction of the chromophore produced by dihydroceramide desaturase-1 (DES1), the putative all-*trans* retinol isomerase in Müller cells, appears to be 9-*cis* retinol. In contrast, the canonical retinal pigment epithelium (RPE) visual cycle produces exclusively 11-*cis* retinal. Here, we used the different absorption spectra of 9-*cis* and 11-*cis* pigments to identify the isoform o... περισσότερα »
Erratum to: The laparoscopic modified Sugarbaker technique is safe and has a low recurrence rate: a multicenter cohort study
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
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The use of patient factors to improve the prediction of operative duration using laparoscopic cholecystectomy
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Abstract Background Reliable prediction of operative duration is essential for improving patient and care team satisfaction, optimizing resource utilization and reducing cost. Current operative scheduling systems are unreliable and contribute to costly over- and underestimation of operative time. We hypothesized that the inclusion of patient-specific factors would improve the accuracy in predicting operative duration. Methods We reviewed all elective laparoscopic cholecystectomies performed at a single institution between 01/2007 and 06/2013. Concurrent procedures were excluded. ... περισσότερα »
5th Anniversary International Fluid Academy Days
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
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A cross sectional study on awareness about injectable polio vaccine among pregnant women and mothers of children under 14 weeks in a rural area of Kannur, North Kerala, India
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
2016-07-07T02-36-11Z *Source:* International Journal of Community Medicine and Public Health Sarada A. K., Thilak S. A., Sushrit A. Neloopant. Background: Poliomyelitis, a highly infectious disease which can cause irreversible total paralysis which mainly affects the children under five years of age. As the Government was introducing the injectable polio vaccine (IPV) from April 2016 in Kerala as a part of polio end game strategy, the study was conducted to assess the awareness about IPV. The aim was to assess the level of knowledge about IPV and attitude towards IPV introduction in... περισσότερα »
Assessment of treatment adherence among hypertensive patients in a coastal area of Karnataka, India
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
2016-07-07T02-36-11Z *Source:* International Journal of Community Medicine and Public Health Sneha D. Mallya, Ashwini Kumar, Asha Kamath, Avinash Shetty, Sravan K. Reddy T., Surabhi Mishra. Background: Hypertension is the most prevalent non communicable disease. With the rising burden of hypertension, prevention of complications such as cardiovascular events or stroke resulting due to uncontrolled blood pressure is of paramount significance. Strict adherence to prescribed antihypertensive medications is the key to blood pressure control and prevention of its complications and mortal... περισσότερα »
Prevalence and factors associated with depression among the elderly in rural areas of Kannur, North Kerala, India: a cross sectional study
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
2016-07-07T02-36-11Z *Source:* International Journal of Community Medicine and Public Health Thilak S. A., Sarada A. K., Sushrit A. Neloopant. Background: The proportion of elderly people aged 60 years and above is increasing in India alarmingly and they are at higher risk of developing neuropsychiatric problems if any associated comorbidities exist. The commonest neuropsychiatric problem is depression and if not diagnosed and treated early will lead to serious psychiatric illnesses, so this study was conducted to know the prevalence and factors associated with geriatric depression ... περισσότερα »
Perioperative complications of obese patients
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Current Opinion in Critical Care from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29wpX7m via IFTTT
Outcomes after successful direct acting antiviral therapy for patients with chronic hepatitis C and decompensated cirrhosis
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Journal of Hepatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29jRjti via IFTTT
'Bad guy' cells blamed in asthma, allergies prove life-saving in deadly C. difficile
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
University of Virginia Health System News from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29wpP7T via IFTTT
Gastroesophageal reflux and sleep disturbances: A bidirectional association in a population-based cohort study, the HUNT study
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
SLEEP from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29jR8yn via IFTTT
Association of preference-based health-related quality of life with weight loss in obese adults
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Value in Health from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29wpSAw via IFTTT
Desirable characteristics of hepatitis C treatment regimens: A review of what we have and what we need
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Infectious Diseases and Therapy from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29jQRvg via IFTTT
Impact of biliary stent-related events in patients diagnosed with advanced pancreatobiliary tumours receiving palliative chemotherapy
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
World Journal of Gastroenterology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29wqgPs via IFTTT
Efficacy and safety of cTACE versus DEB-TACE in patients with hepatocellular carcinoma: A meta-analysis
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Journal of Digestive Diseases from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29jRg0X via IFTTT
Optimal contrast enhancement liquid for dynamic MRI of swallowing
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Journal of Oral Rehabilitation from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29wpW34 via IFTTT
The effect of body mass index on surgical outcomes in patients undergoing pancreatic resection: A systematic review and meta-analysis
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Pancreas from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29jRgxW via IFTTT
Blood test to detect DNA fragments shed from colon cancers accurately predicts disease's recurrence
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Johns Hopkins Medicine from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29wqber via IFTTT
Extra-intestinal findings on magnetic resonance enterography in children with inflammatory bowel disease
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Clinical Radiology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29jQXTQ via IFTTT
Systematic review of tumour necrosis factor antagonists in extraintestinal manifestations in inflammatory bowel disease
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Clinical Gastroenterology and Hepatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29wpUZe via IFTTT
CD4 and CD4/CD8 ratio progression in HIV-HCV infected patients after achievement of SVR
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Journal of Clinical Virology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29jR55x via IFTTT
Development and validation of a risk score for advanced colorectal adenoma recurrence after endoscopic resection
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
World Journal of Gastroenterology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29wqaHp via IFTTT
Risk-Taking Behavior and Impulsivity among HCV-infected Patients
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Psychiatry Research from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29jQX6i via IFTTT
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) in colorectal liver metastasis: The radiologists perspective
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Abdominal Imaging from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29wpYrT via IFTTT
Intravenous and oral contrast vs intravenous contrast alone computed tomography for the visualization of appendix and diagnosis of appendicitis in adult emergency department patients
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 21 δευτερόλεπτα
Canadian Association of Radiologists Journal from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29jR5mb via IFTTT
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Étude comparative de l’activité insecticide des huiles essentielles des espèces de thyms originaires du Sud-Ouest marocain
Résumé Ce travail vise de comparer, pour la première fois, l'activité insecticide des huiles essentielles des espèces de thyms originaires du Sud-Ouest marocain (*Thymus satureioides* Coss., *Thymus broussonetii* Boiss., *Thymus maroccanus* Ball., *Thymus ciliatus* (Desf.) Benth., *Thymus pallidus* Batt., et *Thymus leptobotrys* Murb. L'étude de la toxicité de ces huiles essentielles a été réalisée par le test de contact sur papier-filtre. Les résultats obtenus ont montré que toutes les huiles essentielles testées ont présenté un effet insecticide important vis-à-vis des adultes de... περισσότερα »
Étude comparative de l’activité insecticide des huiles essentielles des espèces de thyms originaires du Sud-Ouest marocain
Résumé Ce travail vise de comparer, pour la première fois, l'activité insecticide des huiles essentielles des espèces de thyms originaires du Sud-Ouest marocain (*Thymus satureioides* Coss., *Thymus broussonetii* Boiss., *Thymus maroccanus* Ball., *Thymus ciliatus* (Desf.) Benth., *Thymus pallidus* Batt., et *Thymus leptobotrys* Murb. L'étude de la toxicité de ces huiles essentielles a été réalisée par le test de contact sur papier-filtre. Les résultats obtenus ont montré que toutes les huiles essentielles testées ont présenté un effet insecticide important vis-à-vis des adultes de... περισσότερα »
Pharmacokinetics and pharmacodynamics of two different landiolol formulations in a healthy Caucasian group
Publication date: 20 September 2016 *Source:*European Journal of Pharmaceutical Sciences, Volume 92 Author(s): Günther Krumpl, Ivan Ulc, Michaela Trebs, Pavla Kadlecová, Juri Hodisch BackgroundTo date, no data have been reported on the pharmacokinetic and pharmacodynamic properties of landiolol, a fast-acting cardioselective β1-adrenergic antagonist, in non-Asian subjects. The aim of this study was to compare two landiolol formulations in healthy Caucasian subjects.Materials and methodsWe conducted a single-center, prospective, double-blinded, randomized study in two cross-over peri... περισσότερα »
Gene polymorphisms and contents of cytochrome P450s have only limited effects on metabolic activities in human liver microsomes
Publication date: 20 September 2016 *Source:*European Journal of Pharmaceutical Sciences, Volume 92 Author(s): Na Gao, Xin Tian, Yan Fang, Jun Zhou, Haifeng Zhang, Qiang Wen, Linjing Jia, Jie Gao, Bao Sun, Jingyao Wei, Yunfei Zhang, Mingzhu Cui, Hailing Qiao Extensive inter-individual variations in pharmacokinetics are considered as a major reason for unpredictable drug responses. As the most important drug metabolic enzymes, inter-individual variations of cytochrome P450 (CYP) activities are not clear in human liver. In this paper, metabolic activities, gene polymorphisms and prote... περισσότερα »
Evaluating inter-campus plan consistency using a knowledge based planning model
Publication date: Available online 6 July 2016 *Source:*Radiotherapy and Oncology Author(s): Sean L. Berry, Rongtao Ma, Amanda Boczkowski, Andrew Jackson, Pengpeng Zhang, Margie Hunt Background and purposeWe investigate whether knowledge based planning (KBP) can identify systematic variations in intensity modulated radiotherapy (IMRT) plans between multiple campuses of a single institution.Material and methodsA KBP model was constructed from 58 prior main campus (MC) esophagus IMRT radiotherapy plans and then applied to 172 previous patient plans across MC and 4 regional sites (RS).... περισσότερα »
Dose prescription in carbon ion radiotherapy: How to compare two different RBE-weighted dose calculation systems
Publication date: Available online 6 July 2016 *Source:*Radiotherapy and Oncology Author(s): Silvia Molinelli, Giuseppe Magro, Andrea Mairani, Naruhiro Matsufuji, Nobuyuki Kanematsu, Taku Inaniwa, Alfredo Mirandola, Stefania Russo, Edoardo Mastella, Azusa Hasegawa, Hiroshi Tsuji, Shigeru Yamada, Barbara Vischioni, Viviana Vitolo, Alfredo Ferrari, Mario Ciocca, Tadashi Kamada, Hirohiko Tsujii, Roberto Orecchia, Piero Fossati Background and purposeIn carbon ion radiotherapy (CIRT), the use of different relative biological effectiveness (RBE) models in the RBE-weighted dose (DRBE) calc... περισσότερα »
The molecular signature of breast cancer metastasis to bone.
[image: wk-health-logo.gif] Distant metastasis during the advanced stage of malignant tumor progression can cause considerable morbidity in cancer patients. Bone is known to be one of the most common sites of distant metastasis in patients with breast cancer (BC). BC metastases in bone are associated with excessive skeletal complications. These complications can be fatal and reduce quality of life of patients. It is important to understand the metastatic process of BC to bone to improve quality of life and design new therapeutic methods. At present, the molecular mechanisms leading... περισσότερα »
Next-generation sequencing in patients with advanced cancer: are we ready for widespread clinical use? A single institute's experience.
[image: wk-health-logo.gif] The next-generation sequencing (NGS) assay targeting cancer-relevant genes has been adopted widely for use in patients with advanced cancer. The primary aim of this study was to assess the clinical utility of commercially available NGS. We retrospectively collected demographic and clinicopathologic data, recommended therapy, and clinical outcomes of 30 patients with a variety of advanced solid tumors referred to Foundation Medicine NGS. The initial pathologic examination was performed at the pathology department of the referring hospital. The comprehensi... περισσότερα »
Status quo of p53 in the treatment of tumors.
[image: wk-health-logo.gif] The p53 gene is pivotal for oncogenesis in a combination of mutations in oncogenes and antioncogenes. The ubiquitous loss of the p53 pathway in human cancers has generated considerable interest in developing p53-targeted cancer therapies, but current ideas and approaches targeting p53 are conflicting. Current researches focus on cancer-selective drugs with therapeutic strategies that both activate and inhibit p53. As p53 is ubiquitously lost in human cancers, the strategy of exogenous p53 addition is reasonable. However, p53 acts not equally in all cell ... περισσότερα »
IJERPH, Vol. 13, Pages 686: Patterns and Associated Factors of Caesarean Delivery Intention among Expectant Mothers in China: Implications from the Implementation of China’s New National Two-Child Policy
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
Objective: This study explores the basic demographic characteristics of expectant mothers in the context of their intentions regarding mode of delivery, in particular, the preference for caesarean delivery, and analyzes the social and psychological factors that influence delivery preference. Method: A cross-sectional survey of pregnant women was conducted during June to August in 2015. This study adopted a stratified sampling method, and 16 representative hospitals in five provinces of China were included. Results: 1755 and 590 of expectant mothers in their first and second pregnanc... περισσότερα »
IJERPH, Vol. 13, Pages 668: The Incidence and Types of Physical Contact Associated with Body Checking Regulation Experience in 13–14 Year Old Ice Hockey Players
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
Background: Ice hockey has one of the highest sport participation and injury rates in youth in Canada. Body checking (BC) is the predominant mechanism of injury in leagues in which it is permitted. The objectives of this study were to determine whether the incidence and types of physical contact differ for Bantam players (aged 13–14 years) who were exposed to BC at Pee Wee level (aged 11–12 years) in Calgary, Alberta versus Bantam players who were not exposed to BC at Pee Wee level in Québec City, Québec. All teams were exposed to BC at bantam level; Methods: A cohort study was cond... περισσότερα »
IJERPH, Vol. 13, Pages 653: Disparities in Under-Five Child Injury Mortality between Developing and Developed Countries: 1990–2013
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
Objective: Using estimates from the 2013 Global Burden of Disease (GBD) study, we update evidence on disparities in under-five child injury mortality between developing and developed countries from 1990 to 2013. Methods: Mortality rates were accessed through the online visualization tool by the GBD study 2013 group. We calculated percent change in child injury mortality rates between 1990 and 2013. Data analysis was conducted separately for <1 year and 1–4 years to specify age differences in rate changes. Results: Between 1990 and 2013, over 3-fold mortality gaps were observed betwe... περισσότερα »
IJERPH, Vol. 13, Pages 659: Pediatric Canadian Triage and Acuity Scale (PaedsCTAS) as a Measure of Injury Severity
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
This research explored whether the pediatric version of the Canadian Triage Acuity Scale (PaedsCTAS) represented a valid alternative indicator for surveillance of injury severity. Every patient presenting in a Canadian emergency department is assigned a CTAS or PaedsCTAS score in order to prioritize access to care and to predict the nature and scope of care that is likely to be required. The five-level PaedsCTAS score ranges from I (resuscitation) to V (non-urgent). A total of 256 children, 0 to 17-years-old, who attended a pediatric hospital for an injury were followed longitudinal... περισσότερα »
IJERPH, Vol. 13, Pages 658: Challenges in the Accurate Surveillance of Booster Seat and Bicycle Helmet Usage by Children: Lessons from the Field
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
Motor vehicle collisions and bicycle collisions and falls are a leading cause of death by preventable injury for children. In order to design, implement and evaluate campaigns and programs aimed at improving child safety, accurate surveillance is needed. This paper examined the challenges that confront efforts to collect surveillance data relevant to child traffic safety, including observation, interview, and focus group methods. Strategies to address key challenges in order to improve the efficiency and accuracy of surveillance methods were recommended. The potential for new techno... περισσότερα »
IJERPH, Vol. 13, Pages 656: Barriers and Enablers to Enacting Child and Youth Related Injury Prevention Legislation in Canada
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
Injury prevention policy is crucial for the safety of Canada’s children; however legislation is not adopted uniformly across the country. This study aimed to identify key barriers and enablers to enacting injury prevention legislation. Purposive snowball sampling identified individuals involved in injury prevention throughout Canada. An online survey asked respondents to identify policies that were relevant to them, and whether legislation existed in their province. Respondents rated the importance of barriers or enablers using a 5-point Likert type scale and included open-ended com... περισσότερα »
IJERPH, Vol. 13, Pages 651: Disparities in Paediatric Injury Mortality between Aboriginal and Non-Aboriginal Populations in British Columbia, 2001–2009
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
Injury is the leading cause of death among children and youth in Canada. Significant disparities in injury mortality rates have been observed between Aboriginal and non-Aboriginal populations, but little is known about the age-, sex-, and mechanism-specific patterns of injury causing death. This study examines paediatric mortality in British Columbia from 2001 to 2009 using comprehensive vital statistics registry data. We highlight important disparities in Aboriginal and non-Aboriginal mortality rates, and use the Preventable Years of Life Lost (PrYLL) metric to identify differences... περισσότερα »
IJERPH, Vol. 13, Pages 657: Predictors of FIFA 11+ Implementation Intention in Female Adolescent Soccer: An Application of the Health Action Process Approach (HAPA) Model
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
The Fédération Internationale de Football (FIFA) 11+ warm-up program is efficacious at preventing lower limb injury in youth soccer; however, there has been poor adoption of the program in the community. The purpose of this study was to determine the utility of the Health Action Process Approach (HAPA) behavior change model in predicting intention to use the FIFA 11+ in a sample of 12 youth soccer teams (coaches n = 10; 12–16 year old female players n = 200). A bespoke cross-sectional questionnaire measured pre-season risk perceptions, outcome expectancies, task self-efficacy, facil... περισσότερα »
IJERPH, Vol. 13, Pages 649: An Analysis of Children Left Unattended in Parked Motor Vehicles in Brazil
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
Our study investigates the incidence of children left unattended in parked motor vehicles in Brazil. These events have been widely explored in the United States but less so abroad, and never in Brazil. Over the period from 2006 to 2015, we collected data from news reports on 31 cases, including 21 fatalities. The circumstances mostly involved a caregiver, especially a parent, forgetting the child (71%), but cases also included the child being intentionally left in the vehicle (23%) or gaining access to the vehicle (3%). Children tended to be forgotten more frequently in fatal cases (... περισσότερα »
IJERPH, Vol. 13, Pages 654: The Extent of Consumer Product Involvement in Paediatric Injuries
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
A challenge in utilising health sector injury data for Product Safety purposes is that clinically coded data have limited ability to inform regulators about product involvement in injury events, given data entry is bound by a predefined set of codes. Text narratives collected in emergency departments can potentially address this limitation by providing relevant product information with additional accompanying context. This study aims to identify and quantify consumer product involvement in paediatric injuries recorded in emergency department-based injury surveillance data. A total o... περισσότερα »
IJERPH, Vol. 13, Pages 674: Patterns of Injury in Hospitalised One-Year-Old Children: Analysis by Trimester of Age Using Coded Data and Textual Description
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
The second year of life is a time of rapid developmental changes. This paper aims to describe the pattern of unintentional injuries to one-year old children in three-month age bands to better understand the risks associated with developmental stages and, therefore, identify opportunities for proactive prevention. Injury surveillance data were used to identify children admitted to hospital in Queensland, Australia for an unintentional injury from 2002–2012. Falls were the most common injury, followed by burns and scalds, contact injuries and poisonings. Falls and contact injuries rem... περισσότερα »
IJERPH, Vol. 13, Pages 669: Children’s Understanding of No Diving Warning Signs: Implications for Preventing Childhood Injury
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
The current study examined children’s understanding of No Diving warning signs. Normally-developing 7 to 10 year olds were asked questions to assess their understanding of text, images, and main messages on No Diving warning signs. These structured interviews were audio recorded and responses were later coded. Results revealed that children understood the behavior advised against (diving), why it is prohibited (can hit head on the bottom), and what can happen (serious injury including hospitalization). They understood that breaking your neck results in limitations in mobility and can... περισσότερα »
IJERPH, Vol. 13, Pages 652: Caregiver Reports of Children’s Activity Participation Following Serious Injury
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
Paediatric trauma can result in significant levels of on-going disability. The aim of this study was to explore the restrictions on activity participation that children experience following serious injury from the perspective of their caregivers. We performed a thematic analysis of transcripts of semi-structured in-depth interviews with the caregivers of 44 seriously injured children, conducted three-years after the injury, and purposively sampled from a population-based cohort study. Both temporary and on-going restrictions on school, sport, leisure and social activities were ident... περισσότερα »
IJERPH, Vol. 13, Pages 685: Types of Obesity and Its Association with the Clustering of Cardiovascular Disease Risk Factors in Jilin Province of China
Αλέξανδρος ΣφακιανάκηςστοOccupational and Environmental Medicine by Alexandros G.SfakianakisΠριν από 33 δευτερόλεπτα
Cardiovascular disease (CVD) has become a serious public health problem in recent years in China. Aggregation of CVD risk factors in one individual increases the risk of CVD and the risk increases substantially with each additional risk factor. This study aims to explore the relationship between the number of clustered CVD risk factors and different types of obesity. A multistage stratified random cluster sampling design was used in this population-based cross-sectional study in 2012. Information was collected by face to face interviews. One-way analysis of variance (ANOVA), chi-squ... περισσότερα »
Airway and head and neck high dependency unit: a single-centre experience
Research Articles M Bannister, P Trotter, A Jawad, D Y Veitch The Journal of Laryngology & Otology,FirstView Article(s), 4 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/29Bqfuy via IFTTT
Cancers, Vol. 8, Pages 64: A Perspective of Immunotherapy for Prostate Cancer
In cancer patients, the immune system is often altered with an excess of inhibitory factors, such as immunosuppressive cytokines, produced by regulatory T cells (Treg) or myeloid-derived suppressor cells (MDSC). The manipulation of the immune system has emerged as one of new promising therapies for cancer treatment, and also represents an attractive strategy to control… Continue reading Cancers, Vol. 8, Pages 64: A Perspective of Immunotherapy for Prostate Cancer
Airway and head and neck high dependency unit: a single-centre experience
Research Articles M Bannister, P Trotter, A Jawad, D Y Veitch The Journal of Laryngology & Otology,FirstView Article(s), 4 pages Abstract from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/29Bqfuy via IFTTT
Pharmaceuticals, Vol. 9, Pages 42: Polylactic Acid—Lemongrass Essential Oil Nanocapsules with Antimi crobial Properties
Polylactic acid was combined with lemongrass essential oil (EO) to produce functional nanocapsules (NCs). The obtained polylactic acid nanoparticles showed antimicrobial activity both with and without the presence of lemongrass oil; however, the presence of EO improved the activity of the NCs. The presence of lemongrass assisted the formation of well-separated NCs and also provided… Continue reading Pharmaceuticals, Vol. 9, Pages 42: Polylactic Acid—Lemongrass Essential Oil Nanocapsules with Antimi crobial Properties
Erratum to: The laparoscopic modified Sugarbaker technique is safe and has a low recurrence rate: a multicenter cohort study
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The use of patient factors to improve the prediction of operative duration using laparoscopic cholecystectomy
Abstract Background Reliable prediction of operative duration is essential for improving patient and care team satisfaction, optimizing resource utilization and reducing cost. Current operative scheduling systems are unreliable and contribute to costly over- and underestimation of operative time. We hypothesized that the inclusion of patient-specific factors would improve the accuracy in predicting operative duration. Methods… Continue reading The use of patient factors to improve the prediction of operative duration using laparoscopic cholecystectomy
Light-emitting diode therapy in exercise-trained mice increases muscle performance, cytochrome c oxidase activity, ATP and cell proliferation J. Biophotonics 8, No. 9, 740–754 (2015)
In the article by C. Ferraresi et al. (DOI: http://ift.tt/29jYcLc), published in J. Biophotonics 8, 740–754 (2015), a statement regarding the approval of some data the authors used is incorrect. This erratum is published to rectify this. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/29wyE1u via IFTTT
Viruses, Vol. 8, Pages 189: A Truncated Nef Peptide from SIVcpz Inhibits the Production of HIV-1 Infectious Progeny
Nef proteins from all primate Lentiviruses, including the simian immunodeficiency virus of chimpanzees (SIVcpz), increase viral progeny infectivity. However, the function of Nef involved with the increase in viral infectivity is still not completely understood. Nonetheless, until now, studies investigating the functions of Nef from SIVcpz have been conducted in the context of the HIV-1… Continue reading Viruses, Vol. 8, Pages 189: A Truncated Nef Peptide from SIVcpz Inhibits the Production of HIV-1 Infectious Progeny
Clinical significance of mitofusin-2 and its signaling pathways in hepatocellular carcinoma
Abstract Background The mitochondrial GTPase mitofusin-2 (MFN2) gene encodes a mitochondrial membrane protein that can induce apoptosis of hepatocellular carcinoma (HCC) via the mitochondrial apoptotic pathway, as validated in our previous research. However, little is known of the clinical significance of MFN2 expression and its signaling pathways in HCC. Methods MFN2 mRNA expression in tumor… Continue reading Clinical significance of mitofusin-2 and its signaling pathways in hepatocellular carcinoma
Toxins, Vol. 8, Pages 212: Distribution and Metabolism of Bt-Cry1Ac Toxin in Tissues and Organs of the Cotton Bollworm, Helicoverpa armigera
Crystal (Cry) proteins derived from Bacillus thuringiensis (Bt) have been widely used in transgenic crops due to their toxicity against insect pests. However, the distribution and metabolism of these toxins in insect tissues and organs have remained obscure because the target insects do not ingest much toxin. In this study, several Cry1Ac-resistant strains of Helicoverpa… Continue reading Toxins, Vol. 8, Pages 212: Distribution and Metabolism of Bt-Cry1Ac Toxin in Tissues and Organs of the Cotton Bollworm, Helicoverpa armigera
A Dynamic Speech Comprehension Test for Assessing Real-World Listening Ability
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
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Common Sound Scenarios: A Context-Driven Categorization of Everyday Sound Environments for Application in Hearing-Device Research
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
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Evaluation of Loudspeaker-Based Virtual Sound Environments for Testing Directional Hearing Aids
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
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Spatial Acoustic Scenarios in Multichannel Loudspeaker Systems for Hearing Aid Evaluation
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
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Effects of Hearing Loss on Dual-Task Performance in an Audiovisual Virtual Reality Simulation of Listening While Walking
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
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The Effects of Hearing Impairment, Age, and Hearing Aids on the Use of Self-Motion for Determining Front/Back Location
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
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A Method for Assessing Auditory Spatial Analysis in Reverberant Multitalker Environments
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
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JAAA CEU Program
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
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Introduction to Special Issue: Towards Ecologically Valid Protocols for the Assessment of Hearing and Hearing Devices
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
} http://ift.tt/29QRHB4
Theoretical Issues of Validity in the Measurement of Aided Speech Reception Threshold in Noise for Comparing Nonlinear Hearing Aid Systems
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
} http://ift.tt/29oZlEp
Never giving up.
*Never giving up.* Surg Neurol Int. 2016;7:65 Authors: Howard D PMID: 27382522 [PubMed] http://ift.tt/29jO4qg
A rare intracranial tumor consisting of malignant anaplastic and papillary meningioma subtypes.
*A rare intracranial tumor consisting of malignant anaplastic and papillary meningioma subtypes.* Surg Neurol Int. 2016;7:64 Authors: Hakan T PMID: 27382521 [PubMed] http://ift.tt/29kLr3N
Poor physical performance may be an early sign of late-age dementia
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Poor physical performance was linked with an increased risk of developing dementia in a study of individuals aged 90 and older who were followed for an average of 2.6 years. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/29Aq9kM via IFTTT
Alzheimer’s risk may be detectable from age 18 with genetic scoring
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Researchers have created a genetic risk score that has the potential to pinpoint which adults are at high risk of Alzheimer’s from the age of 18. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/29yt6Fk via IFTTT
The molecular signature of breast cancer metastasis to bone.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Distant metastasis during the advanced stage of malignant tumor progression can cause considerable morbidity in cancer patients. Bone is known to be one of the most common sites of distant metastasis in patients with breast cancer (BC). BC metastases in bone are associated with excessive skeletal complications. These complications can be fatal and reduce quality […]
Next-generation sequencing in patients with advanced cancer: are we ready for widespread clinical use? A single institute’s experience.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The next-generation sequencing (NGS) assay targeting cancer-relevant genes has been adopted widely for use in patients with advanced cancer. The primary aim of this study was to assess the clinical utility of commercially available NGS. We retrospectively collected demographic and clinicopathologic data, recommended therapy, and clinical outcomes of 30 patients with a variety of advanced […]
Status quo of p53 in the treatment of tumors.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The p53 gene is pivotal for oncogenesis in a combination of mutations in oncogenes and antioncogenes. The ubiquitous loss of the p53 pathway in human cancers has generated considerable interest in developing p53-targeted cancer therapies, but current ideas and approaches targeting p53 are conflicting. Current researches focus on cancer-selective drugs with therapeutic strategies that both […]
A Comparison of Measurements of Change in Respiratory Status in Spontaneously Breathing Volunteers by the ExSpiron Noninvasive Respiratory Volume Monitor Versus the Capnostream Capnometer.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
BACKGROUND: Current respiratory monitoring technologies such as pulse oximetry and capnography have been insufficient to identify early signs of respiratory compromise in nonintubated patients. Pulse oximetry, when used appropriately, will alert the caregiver to an episode of dangerous hypoxemia. However, desaturation lags significantly behind hypoventilation and alarm fatigue due to false alarms poses an additional […]
In Response.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/29urOaQ via IFTTT
In Response.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/29B8BY6 via IFTTT
Anesthesia Emergencies.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/29urU2l via IFTTT
Poor physical performance may be an early sign of late-age dementia
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Poor physical performance was linked with an increased risk of developing dementia in a study of individuals aged 90 and older who were followed for an average of 2.6 years. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/29Aq9kM via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Clinical significance of mitofusin-2 and its signaling pathways in hepatocellular carcinoma
Abstract Background The mitochondrial GTPase mitofusin-2 (*MFN2*) gene encodes a mitochondrial membrane protein that can induce apoptosis of hepatocellular carcinoma (HCC) via the mitochondrial apoptotic pathway, as validated in our previous research. However, little is known of the clinical significance of MFN2 expression and its signaling pathways in HCC. Methods MFN2 mRNA expression in tumor and adjacent non-tumor tissues from 115 patients with HCC was investigated using quantitative real-time PCR. The association of the MFN2 mRNA expression level with clinical and pathologica... περισσότερα »
Integration of legal aspects and human rights approach in palliative care delivery—The Nyeri hospice model
David Musyoki, Sarafina Gichohi, Johnson Ritho and Zipporah Ali from Cancer via ola Kala on Inoreader http://ift.tt/29QRCNO via IFTTT
Kenya Hospices and Palliative Care association: integrating palliative care in public hospitals in Kenya
Zipporah Ali from Cancer via ola Kala on Inoreader http://ift.tt/29oYVhl via IFTTT
The Island Hospice model of palliative care
Thembelihle Khumalo and Valerie Maasdorp from Cancer via ola Kala on Inoreader http://ift.tt/29QS5j4 via IFTTT
Interventions geared towards strengthening the health system of Namibia through the integration of palliative care
Rachel Freeman, Emmanuel BK Luyirika, Eve Namisango and Fatia Kiyange from Cancer via ola Kala on Inoreader http://ift.tt/29oZhEy via IFTTT
Best practices in developing a national palliative care policy in resource limited settings: lessons from five African countries
Emmanuel BK Luyirika, Eve Namisango, Eunice Garanganga, Lidia Monjane, Ntombi Ginindza, Gugulethu Madonsela and Fatia Kiyange from Cancer via ola Kala on Inoreader http://ift.tt/29QSnXd via IFTTT
Adaptive Randomization of Veliparib–Carboplatin Treatment in Breast Cancer
Breast cancer is genetically and clinically heterogeneous, which makes it challenging to identify effective patient-specific therapies. Although mortality due to breast cancer in the United States has decreased, more than 40,000 women in the United States still die from this disease each year.… from Cancer via ola Kala on Inoreader http://ift.tt/29jJcBP via IFTTT
Adaptive Randomization of Neratinib in Early Breast Cancer
The treatment of aggressive, locally advanced breast cancers increasingly includes neoadjuvant therapy before surgical resection, thus providing a window of opportunity to tailor treatments on the basis of early assessments of the molecular characteristics of the cancer and their response to… from Cancer via ola Kala on Inoreader http://ift.tt/29kG44E via IFTTT
I-SPY 2 — Toward More Rapid Progress in Breast Cancer Treatment
[image: NEJMCat_Connect_global_header.gif] Clinical trials of systemic therapy for operable breast cancer are evolving. Our understanding of breast cancer as a family of biologically distinct diseases has implications for patient selection and the optimization of drug choices. In addition, there is a growing dissatisfaction with trials of… from Cancer via ola Kala on Inoreader http://ift.tt/29kFZ0W via IFTTT
I-SPY 2 — A Glimpse of the Future of Phase 2 Drug Development?
[image: NEJMCat_Connect_global_header.gif] The articles by Rugo et al. (pages 23–33) and Park et al. (pages 11–22) in this issue of the Journal report results from the I-SPY (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging and Molecular Analysis) 2 platform, a promising adaptive strategy for matching… from Cancer via ola Kala on Inoreader http://ift.tt/29kG2K3 via IFTTT
The molecular signature of breast cancer metastasis to bone.
[image: wk-health-logo.gif] Distant metastasis during the advanced stage of malignant tumor progression can cause considerable morbidity in cancer patients. Bone is known to be one of the most common sites of distant metastasis in patients with breast cancer (BC). BC metastases in bone are associated with excessive skeletal complications. These complications can be fatal and reduce quality of life of patients. It is important to understand the metastatic process of BC to bone to improve quality of life and design new therapeutic methods. At present, the molecular mechanisms leading... περισσότερα »
Next-generation sequencing in patients with advanced cancer: are we ready for widespread clinical use? A single institute's experience.
[image: wk-health-logo.gif] The next-generation sequencing (NGS) assay targeting cancer-relevant genes has been adopted widely for use in patients with advanced cancer. The primary aim of this study was to assess the clinical utility of commercially available NGS. We retrospectively collected demographic and clinicopathologic data, recommended therapy, and clinical outcomes of 30 patients with a variety of advanced solid tumors referred to Foundation Medicine NGS. The initial pathologic examination was performed at the pathology department of the referring hospital. The comprehensi... περισσότερα »
Status quo of p53 in the treatment of tumors.
[image: wk-health-logo.gif] The p53 gene is pivotal for oncogenesis in a combination of mutations in oncogenes and antioncogenes. The ubiquitous loss of the p53 pathway in human cancers has generated considerable interest in developing p53-targeted cancer therapies, but current ideas and approaches targeting p53 are conflicting. Current researches focus on cancer-selective drugs with therapeutic strategies that both activate and inhibit p53. As p53 is ubiquitously lost in human cancers, the strategy of exogenous p53 addition is reasonable. However, p53 acts not equally in all cell ... περισσότερα »
Outcomes of vascularized versus non-vascularized lymph node transplant in animal models for lymphedema. Review of the literature
Lymph node transfer has been performed to treat lymphedema for several years. The goal of this procedure is to provide a bridge between the lymphatic system distal and proximal to the lymph node dissection. There is a lack of consensus about the necessity of an additional vascular anastomosis for the transplanted lymph nodes. A systematic literature search in Cochrane Library database CENTRAL, MEDLINE, and EMBASE of animal studies using lymph node transplantation with and without additional vascularization was performed in March 2016. The strategy used for the search was: (("Mode... περισσότερα »
Rectal cancers with microscopic circumferential resection margin involvement (R1 resections): Survivals, patterns of recurrence, and prognostic factors
Background and Objectives We have reviewed our series of rectal cancer patients with circumferential resection margin involvement (R1) with particular regard to survival and prognostic factors. Methods R1 rectal cancer patients undergoing surgery at the Leicester Royal Infirmary between 1998 and 2008. Age, gender, radiological, and pathological tumor characteristics, neoadjuvant and adjuvant therapies were examined as prognostic factors on the overall survival (OS) and disease-free survival (DFS) at 5-year follow-up. Results A total of 885 rectal cancers were reviewed. Six hund... περισσότερα »
Obesity is not associated with increased morbidity in patients undergoing cytoreductive surgery with intraperitoneal chemotherapy
Background and Objectives Recent single-institutional series have examined the relationship of body mass index (BMI) in patients undergoing cytoreductive surgery (CRS) and intraperitoneal chemotherapy (IPC) generally without significant increase in serious complications with increasing BMI. This study evaluates the impact of BMI on complication rates using a national cohort. Methods The ACS NSQIP database was queried for patients undergoing concurrent CRS with IPC (2005–2012). Death and serious morbidity (DSM) was the primary outcome. Statistical analyses were performed to determ... περισσότερα »
Blood concentrations of carotenoids and retinol and lung cancer risk: an update of the WCRF–AICR systematic review of published prospective studies
Abstract Carotenoids and retinol are considered biomarkers of fruits and vegetables intake, and are of much interest because of their anti-inflammatory and antioxidant properties; however, there is inconsistent evidence regarding their protective effects against lung cancer. We conducted a meta-analysis of prospective studies of blood concentrations of carotenoids and retinol, and lung cancer risk. We identified relevant prospective studies published up to December 2014 by searching the PubMed and several other databases. We calculated summary estimates of lung cancer risk for the ... περισσότερα »
Sex differences in stress-induced visceral hypersensitivity following early life adversity: a two hit model
Abstract Background Early life adversity (ELA) has been indicated as a risk factor for the development of stress axis dysfunction in adulthood, specifically in females. We previously showed that unpredictable ELA induces visceral hyperalgesia in adult female rats. It remains to be determined whether ELA alters visceral nociceptive responses to stress in adulthood. The current study tested the hypothesis that following ELA, exposure to an adulthood stressor, or second hit, serves as a risk factor for exaggerated stress-induced visceral hypersensitivity that is sex-specific. Methods... περισσότερα »
Development and validation of the brief esophageal dysphagia questionnaire.
*Development and validation of the brief esophageal dysphagia questionnaire.* Neurogastroenterol Motil. 2016 Jul 5; Authors: Taft TH, Riehl M, Sodikoff JB, Kahrilas PJ, Keefer L, Doerfler B, Pandolfino JE Abstract BACKGROUND: Esophageal dysphagia is common in gastroenterology practice and has multiple etiologies. A complication for some patients with dysphagia is food impaction. A valid and reliable questionnaire to rapidly evaluate esophageal dysphagia and impaction symptoms can aid the gastroenterologist in gathering information to inform treatment approach and further evaluat... περισσότερα »
Gastrointestinal care for older people.
*Gastrointestinal care for older people.* Nurs Stand. 2016 Jul 6;30(45):53-63 Authors: Tremayne P, Harrison P Abstract This article discusses gastrointestinal (GI) healthcare in older people. It outlines the physiological changes that occur in the GI tract as a result of ageing, and discusses common GI disorders in older people. These GI disorders include dysphagia, gastrointestinal reflux disease, colorectal cancer, diverticular disease, constipation and anaemia. Healthcare professionals should be aware of the factors that may influence gastrointestinal health in older people, i... περισσότερα »
Paediatric non-IgE mediated food allergy: guide for practitioners.
*Paediatric non-IgE mediated food allergy: guide for practitioners.* N Z Med J. 2016 Feb 19;129(1430):78-88 Authors: Preece K, Blincoe A, Grangaard E, Ostring GT, Purvis D, Sinclair J, Shiek A, Winkler R, Paediatric Allergy Special Interest Group Abstract AIM: Food avoidance in children is increasingly common due to concerns about allergy. We aim to review the current literature on paediatric non-IgE mediated food allergy including what is known about pathophysiology, diagnosis, management and prognosis of common and severe presentations. Considerations regarding appropriate formu... περισσότερα »
[Clinical study of the influence of laryngopharyngeal reflux on quality of life in patients with dysphonia].
[image: http:--journal.yiigle.com-r-cms-jiansuo-] Related Articles *[Clinical study of the influence of laryngopharyngeal reflux on quality of life in patients with dysphonia].* Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Dec;50(12):973-7 Authors: Wang Y, Zhang L, Yu L, Li J, Li J, Zhao Y, Cao J Abstract OBJECTIVE: To explore the morbidity of laryngopharyngeal reflux in patients with dysphonic diseases and to investigate the influence of LPR on the patients. METHODS: One hundred and twenty-seven patients with dysphonic diseases were encountered in Peking University of the ... περισσότερα »
Gastro-oesophageal reflux and worse asthma control in obese children: a case of symptom misattribution?
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Gastro-oesophageal reflux and worse asthma control in obese children: a case of symptom misattribution?* Thorax. 2016 Mar;71(3):238-46 Authors: Lang JE, Hossain J, Holbrook JT, Teague WG, Gold BD, Wise RA, Lima JJ Abstract BACKGROUND: Obese children for unknown reasons report greater asthma symptoms. Asthma and obesity both independently associate with gastro-oesophageal reflux symptoms (GORS). Determining if obesity affects the link between GORS and asthma will help elucidate the obese-asthma phenotype. OBJECTI... περισσότερα »
[Analyses of the characteristics of esophageal motility in patients with pharyngeal paraesthesia who visit the Department of gastroenterology].
[image: http:--journal.yiigle.com-r-cms-jiansuo-] Related Articles *[Analyses of the characteristics of esophageal motility in patients with pharyngeal paraesthesia who visit the Department of gastroenterology].* Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Jul;50(7):569-72 Authors: Wang Z, Chen Y, Guo T Abstract OBJECTIVE: To investigate the influence of the local sensory abnormality in throat while the change of motility in the upper esophageal sphincter (UES) and lower esophageal sphincter (LES), as well as the change of esophageal body in pharyngeal paraesthesia. METHOD... περισσότερα »
[Application of 24-hour multichannel intraluminal impedance in combination with pH monitoring for the diagnosis of laryngopharyngeal reflux: a pilot study].
[image: http:--journal.yiigle.com-r-cms-jiansuo-] Related Articles *[Application of 24-hour multichannel intraluminal impedance in combination with pH monitoring for the diagnosis of laryngopharyngeal reflux: a pilot study].* Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Jul;50(7):564-8 Authors: Wang J, Li J, Li X, Ma N Abstract OBJECTIVE: To explore the diagnostic characteristics of 24 hours multichannel intraluminal impedance-pH (MII-pH) monitoring in patients with laryngopharyngeal reflux (LPR). METHODS: Patients who were suspected to have laryngopharyngeal reflux (LRP) ... περισσότερα »
Esophagogastric junction distensibility in the management of achalasia patients: relation to treatment outcome.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Esophagogastric junction distensibility in the management of achalasia patients: relation to treatment outcome.* Neurogastroenterol Motil. 2015 Oct;27(10):1495-503 Authors: Smeets FG, Masclee AA, Keszthelyi D, Tjwa ET, Conchillo JM Abstract BACKGROUND: Achalasia is characterized by a functional esophagogastric junction (EGJ) obstruction. The functional luminal imaging probe (EndoFLIP) is a method to assess EGJ distensibility. In a homogeneous group of newly diagnosed achalasia patients treated with pneumatic dilat... περισσότερα »
Esophagogastric junction contractility for clinical assessment in patients with GERD: a real added value?
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Esophagogastric junction contractility for clinical assessment in patients with GERD: a real added value?* Neurogastroenterol Motil. 2015 Oct;27(10):1423-31 Authors: Tolone S, De Bortoli N, Marabotto E, de Cassan C, Bodini G, Roman S, Furnari M, Savarino V, Docimo L, Savarino E Abstract BACKGROUND: The role of esophagogastric junction contractile integral (EGJ-CI) as assessed by high-resolution manometry (HRM) is unclear. We aimed to correlate the EGJ-CI with impedance-pH findings in gastro-esophageal reflux dise... περισσότερα »
Association between facial growth pattern and facial muscle activity: A prospective cross-sectional study.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Association between facial growth pattern and facial muscle activity: A prospective cross-sectional study.* Int Orthod. 2015 Jun;13(2):181-94 Authors: Alabdullah M, Saltaji H, Abou-Hamed H, Youssef M Abstract OBJECTIVE: To evaluate the relationship between facial growth pattern and electromyography (EMG) of facial muscles: anterior temporalis, masseter, buccinators, orbicularis oris, mentalis and anterior digastric. PATIENTS AND METHODS: The sample consisted of 77 subjects aged between 18-28 years (mean age 21.10±... περισσότερα »
Clinical and Pulmonary Function Markers of Respiratory Exacerbation Risk in Subjects With Quadriplegic Cerebral Palsy.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Clinical and Pulmonary Function Markers of Respiratory Exacerbation Risk in Subjects With Quadriplegic Cerebral Palsy.* Respir Care. 2015 Oct;60(10):1431-7 Authors: Vianello A, Carraro E, Pipitone E, Marchese-Ragona R, Arcaro G, Ferraro M, Paladini L, Martinuzzi A Abstract BACKGROUND: Although respiratory exacerbations are common in patients with quadriplegic cerebral palsy (CP), little is known about the factors that are related to increased exacerbation risk. This study aimed to identify the clinical and pulmon... περισσότερα »
Clinical outcome of lower esophageal sphincter- and vagus-nerve-preserving partial cardiectomy for early gastric cancer of the subcardia.
[image: http:--production.springer.de-OnlineReso] Related Articles *Clinical outcome of lower esophageal sphincter- and vagus-nerve-preserving partial cardiectomy for early gastric cancer of the subcardia.* Gastric Cancer. 2015 Jul;18(3):669-74 Authors: Matsumoto H, Murakami H, Kubota H, Higashida M, Nakamura M, Hirai T Abstract BACKGROUND: No definitive operative method has been established for the treatment of early subcardial gastric cancer. Our newly developed technique involves local resection of the subcardia while preserving the lower esophageal sphincter and vagus nerve. A... περισσότερα »
Paediatric non-IgE mediated food allergy: guide for practitioners.
*Paediatric non-IgE mediated food allergy: guide for practitioners.* N Z Med J. 2016 Feb 19;129(1430):78-88 Authors: Preece K, Blincoe A, Grangaard E, Ostring GT, Purvis D, Sinclair J, Shiek A, Winkler R, Paediatric Allergy Special Interest Group Abstract AIM: Food avoidance in children is increasingly common due to concerns about allergy. We aim to review the current literature on paediatric non-IgE mediated food allergy including what is known about pathophysiology, diagnosis, management and prognosis of common and severe presentations. Considerations regarding appropriate formu... περισσότερα »
[Clinical study of the influence of laryngopharyngeal reflux on quality of life in patients with dysphonia].
[image: http:--journal.yiigle.com-r-cms-jiansuo-] Related Articles *[Clinical study of the influence of laryngopharyngeal reflux on quality of life in patients with dysphonia].* Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Dec;50(12):973-7 Authors: Wang Y, Zhang L, Yu L, Li J, Li J, Zhao Y, Cao J Abstract OBJECTIVE: To explore the morbidity of laryngopharyngeal reflux in patients with dysphonic diseases and to investigate the influence of LPR on the patients. METHODS: One hundred and twenty-seven patients with dysphonic diseases were encountered in Peking University of the ... περισσότερα »
Gastro-oesophageal reflux and worse asthma control in obese children: a case of symptom misattribution?
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Gastro-oesophageal reflux and worse asthma control in obese children: a case of symptom misattribution?* Thorax. 2016 Mar;71(3):238-46 Authors: Lang JE, Hossain J, Holbrook JT, Teague WG, Gold BD, Wise RA, Lima JJ Abstract BACKGROUND: Obese children for unknown reasons report greater asthma symptoms. Asthma and obesity both independently associate with gastro-oesophageal reflux symptoms (GORS). Determining if obesity affects the link between GORS and asthma will help elucidate the obese-asthma phenotype. OBJECTI... περισσότερα »
[Transcervical tongue partial reduction combined with uvulopalatopharyngoplasty in treatment of obstructive sleep apnea-hypopnea syndrome].
[image: http:--journal.yiigle.com-r-cms-jiansuo-] Related Articles *[Transcervical tongue partial reduction combined with uvulopalatopharyngoplasty in treatment of obstructive sleep apnea-hypopnea syndrome].* Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Aug;50(8):657-60 Authors: Wang Y, Liu Z, Wang X, Zhang Y, Li Z, Cao Y, Su H Abstract OBJECTIVE: To treat severe obstructive sleep apnea-hypopnea syndrome (OSAHS) with transcervical tongue partial reduction and evaluate treating effect. METHODS: Forty four patients of severe OSAHS were treated with transcervical tongue parti... περισσότερα »
[Analyses of the characteristics of esophageal motility in patients with pharyngeal paraesthesia who visit the Department of gastroenterology].
[image: http:--journal.yiigle.com-r-cms-jiansuo-] Related Articles *[Analyses of the characteristics of esophageal motility in patients with pharyngeal paraesthesia who visit the Department of gastroenterology].* Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Jul;50(7):569-72 Authors: Wang Z, Chen Y, Guo T Abstract OBJECTIVE: To investigate the influence of the local sensory abnormality in throat while the change of motility in the upper esophageal sphincter (UES) and lower esophageal sphincter (LES), as well as the change of esophageal body in pharyngeal paraesthesia. METHOD... περισσότερα »
[Application of 24-hour multichannel intraluminal impedance in combination with pH monitoring for the diagnosis of laryngopharyngeal reflux: a pilot study].
[image: http:--journal.yiigle.com-r-cms-jiansuo-] Related Articles *[Application of 24-hour multichannel intraluminal impedance in combination with pH monitoring for the diagnosis of laryngopharyngeal reflux: a pilot study].* Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Jul;50(7):564-8 Authors: Wang J, Li J, Li X, Ma N Abstract OBJECTIVE: To explore the diagnostic characteristics of 24 hours multichannel intraluminal impedance-pH (MII-pH) monitoring in patients with laryngopharyngeal reflux (LPR). METHODS: Patients who were suspected to have laryngopharyngeal reflux (LRP) ... περισσότερα »
Measurement of Voluntary Cough Production and Airway Protection in Parkinson Disease.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Measurement of Voluntary Cough Production and Airway Protection in Parkinson Disease.* Arch Phys Med Rehabil. 2016 Mar;97(3):413-20 Authors: Silverman EP, Carnaby G, Singletary F, Hoffman-Ruddy B, Yeager J, Sapienza C Abstract OBJECTIVE: To examine relations between peak expiratory (cough) airflow rate and swallowing symptom severity in participants with Parkinson disease (PD). DESIGN: Cross-sectional study. SETTING: Outpatient radiology clinic at an acute care hospital. PARTICIPANTS: Men and women with PD (N=68).... περισσότερα »
Assessment of bolus transit with intraluminal impedance measurement in patients with esophageal motility disorders.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Assessment of bolus transit with intraluminal impedance measurement in patients with esophageal motility disorders.* Neurogastroenterol Motil. 2015 Oct;27(10):1446-52 Authors: Bogte A, Bredenoord AJ, Oors J, Siersema PD, Smout AJ Abstract BACKGROUND: The clinical management of patients with non-obstructive dysphagia is notoriously difficult. Esophageal impedance measurement can be used to measure esophageal bolus transit without the use of radiation exposure to patients. However, validation of measurement of bolus... περισσότερα »
End-tidal CO2 on admission is associated with hemorrhagic shock and predicts the need for massive transfusion as defined by the critical administration threshold: A pilot study
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Delay to surgery does not affect survival following osteoporotic femoral fractures
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Triceps-reflecting anconeus pedicle approach with double precontoured locking plate fixation is efficient in the treatment of orthopaedic trauma association type C distal humerus fracture
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Validation of electronic administration of knee surveys among ACL-injured patients
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Hypoglycemic episodes are associated with inflammatory status in patients with type 1 diabetes mellitus
Atherosclerosis from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/29QZnmZ via IFTTT
Term pregnancy with choriocarcinoma presenting as severe fetal anemia and postpartum hemorrhage
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Incidences of acute kidney injury, dialysis, and graft loss following intravenous administration of low-osmolality iodinated contrast in patients with kidney transplants
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Major genitourinary-related bicycle trauma: Results from 20 years at a level-1 trauma center
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Mortality in trauma patients with active arterial bleeding managed by embolization or surgical packing: An observational cohort study of 66 patients
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Hypothermia as a predictor for mortality in trauma patients at admittance to the intensive care unit
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Clinical relevance of seasonal changes in the prevalence of ureterolithiasis in the diagnosis of renal colic
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Endoscopic fibular groove deepening for stabilisation of recurrent peroneal tendons instability in a patient with open physes
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A combined approach for the treatment of lateral and posterolateral tibial plateau fractures
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High rate of drug overdose deaths among adults recently released from incarceration: Study
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Factors Associated with the Likelihood of Hospitalization Following Emergency Department Visits for Behavioral Health Conditions
[image: cover.gif?v=1&s=28b3a020f5038a547166cee1] Abstract Study Objectives Behavioral health-related emergency department (ED) visits have been linked with ED overcrowding, an increased demand on limited resources and a longer length of stay due in part to patients being admitted to the hospital but waiting for an inpatient bed. The present study examines factors associated with the likelihood of hospital admission for ED patients with behavioral health conditions at 16 hospital-based EDs in a large urban area in the southern United States. Methods Using *Andersen's Behavioral Mo... περισσότερα »
The Physician-as-Stakeholder: An Exploratory Qualitative Analysis of Physicians’ Motivations for Using Shared Decision-Making in the Emergency Department
[image: cover.gif?v=1&s=28b3a020f5038a547166cee1] Abstract Background Shared decision-making (SDM) is increasingly recognized as an important facet of patient-centered care. Despite growing interest in SDM in the emergency department, little is known about emergency physicians’ (EP) motivations for using SDM. Understanding current patterns of SDM use and EP's rationale for using SDM is essential for the development of interventions to increase use. Objectives Recognizing the emergency physician as an important stakeholder in SDM research, we sought to identify and explore factors ... περισσότερα »
Emergencies and acute diseases in the collected works [omicron]f Hippocrates: observation, examination, prognosis, therapy.
The collected works [omicron]f Hippocrates include a wealth of references to emergencies and acute conditions; if the physician could treat these, he would be considered superior to his colleagues. Works most relevant to current Emergency Medicine are presented. They indicate Hippocrates' remarkable insight and attention to the value of close observation, meticulous clinical examination, and prognosis. Hippocrates and his followers disdained mystery and were not satisfied until they had discovered a rational cause to diseases. They assigned great significance to distressing signs an... περισσότερα »
[The false-negative reasons of positioning test in benign paroxysmal positional vertigo].
Related Articles *[The false-negative reasons of positioning test in benign paroxysmal positional vertigo].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Jan;30(1):19-21 Authors: Ma X, Si F, Liu Y, Han L, Jing Y, Yu L Abstract OBJECTIVE: To analyze the false-negative proportion and reasons of positioning test in benign paroxysmal positional vertigo (BPPV). METHOD: Sixty-eight cases were reviewed and analyzed during February to April 2009. All patients had typical clinical history of BPPV and diagnosed by positioning test,and all were treated with PRM successfully. If posit... περισσότερα »
[The efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV].
Related Articles *[The efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV].* Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 May;29(10):934-6 Authors: Zhou X, Yu Y, Zhao Y, Wang Y, Liu Z, Liu Q Abstract OBJECTIVE: To evaluate the efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV. METHOD: A total of 63 patients diagnosed with sudden sensorineural hearing loss with BPPV were treated through OPD. Patients were divided into three groups: 20 cases in intratympanic dexamethason... περισσότερα »
Factors Associated with the Likelihood of Hospitalization Following Emergency Department Visits for Behavioral Health Conditions
[image: cover.gif?v=1&s=28b3a020f5038a547166cee1] Abstract Study Objectives Behavioral health-related emergency department (ED) visits have been linked with ED overcrowding, an increased demand on limited resources and a longer length of stay due in part to patients being admitted to the hospital but waiting for an inpatient bed. The present study examines factors associated with the likelihood of hospital admission for ED patients with behavioral health conditions at 16 hospital-based EDs in a large urban area in the southern United States. Methods Using *Andersen's Behavioral Mo... περισσότερα »
The Physician-as-Stakeholder: An Exploratory Qualitative Analysis of Physicians’ Motivations for Using Shared Decision-Making in the Emergency Department
[image: cover.gif?v=1&s=28b3a020f5038a547166cee1] Abstract Background Shared decision-making (SDM) is increasingly recognized as an important facet of patient-centered care. Despite growing interest in SDM in the emergency department, little is known about emergency physicians’ (EP) motivations for using SDM. Understanding current patterns of SDM use and EP's rationale for using SDM is essential for the development of interventions to increase use. Objectives Recognizing the emergency physician as an important stakeholder in SDM research, we sought to identify and explore factors ... περισσότερα »
Emergencies and acute diseases in the collected works [omicron]f Hippocrates: observation, examination, prognosis, therapy.
The collected works [omicron]f Hippocrates include a wealth of references to emergencies and acute conditions; if the physician could treat these, he would be considered superior to his colleagues. Works most relevant to current Emergency Medicine are presented. They indicate Hippocrates' remarkable insight and attention to the value of close observation, meticulous clinical examination, and prognosis. Hippocrates and his followers disdained mystery and were not satisfied until they had discovered a rational cause to diseases. They assigned great significance to distressing signs an... περισσότερα »
Introduction to Special Issue: Towards Ecologically Valid Protocols for the Assessment of Hearing and Hearing Devices
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Theoretical Issues of Validity in the Measurement of Aided Speech Reception Threshold in Noise for Comparing Nonlinear Hearing Aid Systems
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A Dynamic Speech Comprehension Test for Assessing Real-World Listening Ability
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Common Sound Scenarios: A Context-Driven Categorization of Everyday Sound Environments for Application in Hearing-Device Research
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Evaluation of Loudspeaker-Based Virtual Sound Environments for Testing Directional Hearing Aids
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Spatial Acoustic Scenarios in Multichannel Loudspeaker Systems for Hearing Aid Evaluation
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Effects of Hearing Loss on Dual-Task Performance in an Audiovisual Virtual Reality Simulation of Listening While Walking
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Introduction to Special Issue: Towards Ecologically Valid Protocols for the Assessment of Hearing and Hearing Devices
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Theoretical Issues of Validity in the Measurement of Aided Speech Reception Threshold in Noise for Comparing Nonlinear Hearing Aid Systems
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The Effects of Hearing Impairment, Age, and Hearing Aids on the Use of Self-Motion for Determining Front/Back Location
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A Dynamic Speech Comprehension Test for Assessing Real-World Listening Ability
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A Method for Assessing Auditory Spatial Analysis in Reverberant Multitalker Environments
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Common Sound Scenarios: A Context-Driven Categorization of Everyday Sound Environments for Application in Hearing-Device Research
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JAAA CEU Program
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Evaluation of Loudspeaker-Based Virtual Sound Environments for Testing Directional Hearing Aids
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Spatial Acoustic Scenarios in Multichannel Loudspeaker Systems for Hearing Aid Evaluation
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Effects of Hearing Loss on Dual-Task Performance in an Audiovisual Virtual Reality Simulation of Listening While Walking
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The Effects of Hearing Impairment, Age, and Hearing Aids on the Use of Self-Motion for Determining Front/Back Location
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A Method for Assessing Auditory Spatial Analysis in Reverberant Multitalker Environments
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JAAA CEU Program
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5th Anniversary International Fluid Academy Days
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Incidence, Surgical Treatment, and Prognosis of Anorectal Melanoma From 1973 to 2011: A Population-Based SEER Analysis.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Incidence, Surgical Treatment, and Prognosis of Anorectal Melanoma From 1973 to 2011: A Population-Based SEER Analysis.* Medicine (Baltimore). 2016 Feb;95(7):e2770 Authors: Chen H, Cai Y, Liu Y, He J, Hu Y, Xiao Q, Hu W, Ding K Abstract Anorectal melanoma (AM) is a rare type of melanoma that accounts for 0.4% to 1.6% of total malignant melanomas. The incidence of AM increases over time, and it remains highly lethal, with a 5-year survival rate of 6% to 22%. Considering the rare nature of this disease, most studies ... περισσότερα »
Eyelid Melanoma
An 87-year-old man presented for treatment of a stye on his left upper eyelid. Despite conservative interventions, the stye had persisted and the skin had become noticeably darker over several weeks (Panels A and B). He reported itching but no pain or bleeding. His risk factors for skin cancer… from Melanoma via xlomafota13 on Inoreader http://ift.tt/29jFvfo
Computer-Aided Diagnosis of Micro-Malignant Melanoma Lesions Applying Support Vector Machines.
*Computer-Aided Diagnosis of Micro-Malignant Melanoma Lesions Applying Support Vector Machines.* Biomed Res Int. 2016;2016:4381972 Authors: Jaworek-Korjakowska J Abstract Background. One of the fatal disorders causing death is malignant melanoma, the deadliest form of skin cancer. The aim of the modern dermatology is the early detection of skin cancer, which usually results in reducing the mortality rate and less extensive treatment. This paper presents a study on classification of melanoma in the early stage of development using SVMs as a useful technique for data classification... περισσότερα »
The evolution of combined molecular targeted therapies to advance the therapeutic efficacy in melanoma: a highlight of vemurafenib and cobimetinib.
*The evolution of combined molecular targeted therapies to advance the therapeutic efficacy in melanoma: a highlight of vemurafenib and cobimetinib.* Onco Targets Ther. 2016;9:3739-52 Authors: Medina TM, Lewis KD Abstract Metastatic melanoma is an aggressive, rapidly progressive disease which historically had very few effective treatment options. However, since 2011, the therapeutic landscape of melanoma has undergone a dramatic transformation with two distinct approaches and has catalyzed the successful advancement in the clinical field of immuno-oncology. In addition, the reco... περισσότερα »
Apolipoprotein A-I: A Molecule of Diverse Function.
*Apolipoprotein A-I: A Molecule of Diverse Function.* Indian J Clin Biochem. 2016 Jul;31(3):253-9 Authors: Mangaraj M, Nanda R, Panda S Abstract Apolipoprotein A-I (apo A-I) an indispensable component and a major structural protein of high-density lipoprotein (HDL), plays a vital role in reverse cholesterol transport and cellular cholesterol homeostasis since its identification. Its multifunctional role in immunity, inflammation, apoptosis, viral, bacterial infection etc. has crossed its boundary of its potential of protecting cardiovascular system and lowering cardiovascular dis... περισσότερα »
Pre-diagnostic leukocyte mitochondrial DNA copy number and skin cancer risk.
*Pre-diagnostic leukocyte mitochondrial DNA copy number and skin cancer risk.* Carcinogenesis. 2016 Jul 5; Authors: Meng S, De Vivo I, Liang L, Giovannucci E, Tang JY, Han J Abstract No previous study has examined the association between mtDNA copy number (mtCN) and skin cancer risk prospectively. We examined the associations between peripheral blood leukocytes mtCN level and the risks of skin cancers in a case-control study nested within the Nurses' Health Study of non-Hispanic White women, including 272 melanoma cases and 293 controls, 508 squamous cell carcinoma (SCC) cases an... περισσότερα »
Efficacy of immunotherapy for metastatic mucosal melanoma.
*Efficacy of immunotherapy for metastatic mucosal melanoma.* Immunotherapy. 2016 Jul;8(8):843-5 Authors: Shreders A, Joseph RW PMID: 27381682 [PubMed - in process] from Melanoma via xlomafota13 on Inoreader http://ift.tt/29AAXix
Nivolumab-induced chronic inflammatory demyelinating polyradiculoneuropathy mimicking rapid-onset Guillain-Barré syndrome: a case report.
*Nivolumab-induced chronic inflammatory demyelinating polyradiculoneuropathy mimicking rapid-onset Guillain-Barré syndrome: a case report.* Jpn J Clin Oncol. 2016 Jul 5; Authors: Tanaka R, Maruyama H, Tomidokoro Y, Yanagiha K, Hirabayashi T, Ishii A, Okune M, Inoue S, Sekine I, Tamaoka A, Fujimoto M Abstract Nivolumab, an anti-programmed death-1-specific monoclonal antibody, has demonstrated a durable response and effect on overall survival and has become one of the standard treatments for patients with advanced melanoma. Reported herein is a case of nivolumab-induced chronic inf... περισσότερα »
Clinical Prognostic Markers in Stage IIIB Melanoma.
*Clinical Prognostic Markers in Stage IIIB Melanoma.* Ann Surg Oncol. 2016 Jul 5; Authors: Madu MF, Wouters MW, Klop WM, van der Hiel B, van de Wiel BA, Jóźwiak K, van der Hage JA, van Akkooi AC Abstract BACKGROUND: Locoregional treatment is often insufficient to guarantee long-term disease-free survival (DFS) in American Joint Committee on Cancer stage IIIB melanoma, and, in order to improve survival, effective neoadjuvant and adjuvant strategies are needed . Selecting patients for these strategies requires risk stratification, for which clinical and molecular biomarkers can be ... περισσότερα »
Benefit Cost Analysis of Three Skin Cancer Public Education Mass-Media Campaigns Implemented in New South Wales, Australia.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Benefit Cost Analysis of Three Skin Cancer Public Education Mass-Media Campaigns Implemented in New South Wales, Australia.* PLoS One. 2016;11(1):e0147665 Authors: Doran CM, Ling R, Byrnes J, Crane M, Shakeshaft AP, Searles A, Perez D Abstract Public education mass media campaigns are an important intervention for influencing behaviour modifications. However, evidence on the effectiveness of such campaigns to encourage the population to reduce sun exposure is limited. This study investig... περισσότερα »
An open-label, dose-escalation study to evaluate the safety and pharmacokinetics of CEP-9722 (a PARP-1 and PARP-2 inhibitor) in combination with gemcitabine and cisplatin in patients with advanced solid tumors.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] *An open-label, dose-escalation study to evaluate the safety and pharmacokinetics of CEP-9722 (a PARP-1 and PARP-2 inhibitor) in combination with gemcitabine and cisplatin in patients with advanced solid tumors.* Anticancer Drugs. 2016 Apr;27(4):342-8 Authors: Awada A, Campone M, Varga A, Aftimos P, Frenel JS, Bahleda R, Gombos A, Bourbouloux E, Soria JC Abstract Poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors may potentiate chemotherapy by hindering DNA damage repair pathways. CEP-9722 is the prodrug of CEP-8983, a selective in... περισσότερα »
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