09:53
OtoRhinoLaryngology - Head and Neck Surgery
Introduction: Cochlear implantation (CI) in subjects with unilateral profound sensorineural hearing loss was investigated. The authors of the present study demonstrated the binaural auditory outcomes in a 12- and 36-month prospective cohort outcome study. The present study aimed to do a long-term (LT)...
09:53
Cancer
Abstract Purpose Endometrial carcinoma is the most common gynecologic malignancy in both developed and some developing countries. Unlike cervical cancer, for which there is routine screening, only patients symptomatic for endometrial carcinoma typically seek medical help for its diagnosis and treatment....
09:52
Medicine by Sfakianakis G. Alexandros
High-pitched sung vowels may be considered phonetically "underspecified" because of (i) the tuning of the F1 to the f0 accompanying pitch raising and (ii) the wide harmonic spacing of the voice source resulting in the undersampling of the vocal tract transfer function. Therefore, sung vowel intelligibility...
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: Available online 12 August 2016Source:Journal of Allergy and Clinical Immunology Author(s): Johanna Bellach, Veronika Schwarz, Birgit Ahrens, Valérie Trendelenburg, Özlem Aksünger, Birgit Kalb, Bodo Niggemann, Thomas Keil, Kirsten Beyer BackgroundHen's egg is the most common cause...
09:52
Medicine by Sfakianakis G. Alexandros
Dexmedetomidine is a selective alpha-2-adrenoceptor agonist used as an adjuvant for regional anaesthesia. We studied its efficacy as an adjuvant to lidocaine in infraorbital nerve block in 90 patients divided equally into three groups. The first group (control) was given 2% lidocaine 2ml only, the second,...
09:52
Medicine by Sfakianakis G. Alexandros
The causes of severe asthma exacerbations remain unknown and outdoor fungi spores may be unrecognised contributors. Several outdoor fungi taxa, not previously reported before with children, are associated with childhood asthma hospitalisations. http://ift.tt/2bljLjK
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: July–August 2016Source:Acta Otorrinolaringologica (English Edition), Volume 67, Issue 4 Author(s): Jesús José Fraile Rodrigo, Ana I. Cisneros, Jesús Obón, Carmen Yus, Rafael Crovetto, Miguel A. Crovetto, Jaime Whyte ObjectivesTo analyse the ontogeny of the superior semicircular canal...
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: July–August 2016Source:Acta Otorrinolaringologica (English Edition), Volume 67, Issue 4 Author(s): Cristiana Coimbra, André Cunha, Edite Coimbra Ferreira, Artur Condé http://ift.tt/2bluWdo
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: July–August 2016Source:Acta Otorrinolaringologica (English Edition), Volume 67, Issue 4 Author(s): Pascual Canals, Belén Pérez del Valle, Francisco Lopez, Amparo Marco IntroductionIt has been a long time since subjective tinnitus cases were described for the first time but they still...
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: July–August 2016Source:Acta Otorrinolaringologica (English Edition), Volume 67, Issue 4 Author(s): Tamara González-Paz, Abdul R. Nehme-Paz, Nieves Rodríguez-Acevedo, Ismael Arán-González http://ift.tt/2aPZbVM
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: July–August 2016Source:Acta Otorrinolaringologica (English Edition), Volume 67, Issue 4 Author(s): Iván Domenech Juan, Paula Cruz Toro, Ángela Callejo Castillo, Rafael Moya, Jorge L. Merán Gil, Ricardo Bartel The middle fossa approach is a surgical technique that is very useful for...
09:52
Medicine by Sfakianakis G. Alexandros
The vocal fold microflap technique is the ideal to remove benign vocal fold pathology. Our objective is to compare the amplitudes of the mucosal wave before and after the closure of microflap defect with fibrin glue, and when microflap is left to heal by secondary intention. http://ift.tt/2aQ8ogW
09:52
Medicine by Sfakianakis G. Alexandros
Abstract A chemical-activated carbon (CAC) was prepared by phosphoric acid activation of olive stone. The CAC was characterized using various analytical techniques and evaluated for the removal of amoxicillin from aqueous solutions under different operating conditions (initial concentration, 12.5–100 mg L−1,...
09:52
Medicine by Sfakianakis G. Alexandros
Our randomized and placebo-controlled Hen's-Egg-Allergy-Prevention-Study HEAP in infants from the general population showed that early introduction of hen's egg at 4-6 months does not protect from hen's egg allergy but results in frequent anaphylactic reactions. http://ift.tt/2b0QG9f
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: Available online 12 August 2016Source:Journal of Allergy and Clinical Immunology Author(s): Rachel Tham, Don Vicendese, Shyamali Dharmage, Rob J. Hyndman, Ed Newbigin, Emma Lewis, Molly O'Sullivan, Adrian J. Lowe, Philip Taylor, Philip Bardin, Mimi L.K. Tang, Michael J. Abramson,...
09:52
Medicine by Sfakianakis G. Alexandros
Even though many studies have explored the problem of voice disorders among teachers worldwide, this problem is still not adequately studied in Egypt. The following study was conducted to investigate the risk factors of voice disorders among an Egyptian sample of school teachers, to measure the effect...
09:52
Medicine by Sfakianakis G. Alexandros
Abstract As part of a research project, the concentrations of Cd, Cu, Pb, V, and Zn in the tissues of Styela plicata were investigated for the first time to determine if S. plicata is a suitable biological indicator for biomonitoring of heavy metals in eastern Aegean Sea coastal waters. To examine the...
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: July–August 2016Source:Acta Otorrinolaringologica (English Edition), Volume 67, Issue 4 Author(s): Faustino Núñez-Batalla, Sabel Noriega-Iglesias, Maite Guntín-García, Pilar Carro-Fernández, José Luis Llorente-Pendás Introduction and objectivesConventional audiometry is the gold standard...
09:52
Medicine by Sfakianakis G. Alexandros
Abstract An alternative method to control rice blast (Magnaporthe oryzae) is to include biological agent in the disease management strategy. The objective of this study was to assess the leaf blast-suppressing effects of rice phylloplane fungi. One Cladosporium sp. phylloplane fungus was shown to possess...
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: July–August 2016Source:Acta Otorrinolaringologica (English Edition), Volume 67, Issue 4 Author(s): Joan Lop-Gros, Juan R. Gras-Cabrerizo, Carolina Bothe-González, Juan R. Montserrat-Gili, Anna Sumarroca-Trouboul, Humbert Massegur-Solench Introduction and objectivesThe fungus ball...
09:52
Medicine by Sfakianakis G. Alexandros
Abstract Toxins produced by cyanobacteria in freshwater ecosystems constitute a serious health risk worldwide for humans that may use the affected water bodies for recreation, drinking water, and/or irrigation. Cyanotoxins have also been deemed responsible for loss of animal life in many places around...
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: July–August 2016Source:Acta Otorrinolaringologica (English Edition), Volume 67, Issue 4 Author(s): Eduard Esteller, Demetrio Mulas, Raúl Haspert, Eusebi Matiñó, Roser López, Montserrat Girabent-Farrés IntroductionDrug-induced sedation endoscopy is a valid tool to assess site obstruction...
09:52
Medicine by Sfakianakis G. Alexandros
• Sleep disturbance in patients with unipolar disorder may take either the form of insomnia or hypersomnia, with the latter occurring less frequently.• Patients with bipolar disorder may show decreased need for sleep without dissatisfaction with sleep quality.• Severe insomnia in unipolar and bipolar...
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: July–August 2016Source:Acta Otorrinolaringologica (English Edition), Volume 67, Issue 4 Author(s): Francina Aguilar, Deysi Barbara García, Francisco Crego, Ángel Serrano http://ift.tt/2aPXJD2
09:52
Medicine by Sfakianakis G. Alexandros
Vocal polyps do not have a well-defined therapeutic indication. The recommended treatment is often laryngeal microsurgery, followed by postoperative speech therapy. Speech therapy as the initial treatment for polyps is a new concept and aims to modify inappropriate vocal behavior, adjust the voice quality,...
09:52
Medicine by Sfakianakis G. Alexandros
Publication date: July–August 2016Source:Acta Otorrinolaringologica (English Edition), Volume 67, Issue 4 Author(s): Miguel Ángel Arístegui Ruiz, Ricardo José González-Orús Álvarez-Morujo, Carlos Martín Oviedo, Fernando Ruiz-Juretschke, Roberto García Leal, Bartolomé Scola Yurrita Introduction and...
09:52
Medicine by Sfakianakis G. Alexandros
We herein report the case of a patient presenting with myxofibrosarcoma (MFS) who underwent treatment with surgery, proton beam therapy (PBT), and pazopanib. A 64-year-old male was diagnosed with MFS, which ranged from the posterior neck to the shoulder. Surgery was performed as an initial treatment;...
09:51
Medicine by Sfakianakis G. Alexandros
Parkinson's disease (PD) is a movement disorder and is associated with some of the intellectual disabilities like cognitive dysfunctions. PD associated cognitive dysfunctions have been proved well in both preclinical and clinical set ups. Like other neurodegenerative diseases, insults to mitochondria...
09:51
Medicine by Sfakianakis G. Alexandros
Background: A wide class of human diseases and neurodegenerative disorders, such as Alzheimer's disease, is due to the failure of a specific peptide or protein to keep its native functional conformational state and to undergo a conformational change into a misfolded state, triggering the formation of...
09:51
Medicine by Sfakianakis G. Alexandros
P-glycoprotein (P-gp) is well known to cause multidrug resistance (MDR) in cancer cells. This MDR leads to cancer recurrence which is a major obstacle in cancer treatment. High P-gp expression has been observed in the population of cancer stem cells (CSCs) having self-renewal potential. Early detection...
09:51
Medicine by Sfakianakis G. Alexandros
Monoamine oxidase-A and B have been studied over a long period as one of the promising drug targets for the treatment of depression and neurodegenerative disorders. Commonly, MAO-A is associated with depression because of its relation with the control of serotonin levels. On the other hand, MAO-B has...
09:51
Medicine by Sfakianakis G. Alexandros
Abstract Sleep complaints are reported by 40–60 % of menopausal women. Poor sleep is a risk factor for cardiovascular disease, diabetes, and obesity. The effect of menopausal hormone therapy on sleep quality is unclear. A systematic review and meta-analysis were conducted to summarize the efficacy of...
09:51
Medicine by Sfakianakis G. Alexandros
Abstract A chemical-activated carbon (CAC) was prepared by phosphoric acid activation of olive stone. The CAC was characterized using various analytical techniques and evaluated for the removal of amoxicillin from aqueous solutions under different operating conditions (initial concentration, 12.5–100 mg L−1,...
09:51
Medicine by Sfakianakis G. Alexandros
Bipolar disorder (BD) affects 1 to 1.5% of the world population and consists of at least one manic episode (or hypomanic) associated with depressive episodes, interspersed with periods of euthymic mood. Recurrent crises lead to significant disability in BD patients, and correlates negatively to social...
09:51
Medicine by Sfakianakis G. Alexandros
Background: Diseases perceived as neglected tropical infections are generally caused by parasites which reach poor, underserved populations (primarily infrastructure), cause serious damage to health, and many deaths. AIDS and tuberculosis, (although not classified as neglected by WHO), are discriminated...
09:51
Medicine by Sfakianakis G. Alexandros
Benzopyrone derivatives (Coumarins) are well known inhibitors of P-glycoprotein (P-gp) mediated efflux. The high expression level of these efflux proteins promotes the growth of breast cancer stem cells (CSCs). The activity of breast CSCs is directly affected by the inhibition of efflux proteins by benzopyrone...
09:51
Medicine by Sfakianakis G. Alexandros
Diabetes is a metabolic disorder and over the past decades, it has become a major cause of morbidity and mortality affecting the youth and middle-aged as it is the fourth leading cause of disease related to death. In both type 1 and type 2 diabetes the severe pathogenesis cause micro vascular complications:...
09:51
Medicine by Sfakianakis G. Alexandros
http://ift.tt/2azelTo
09:51
Medicine by Sfakianakis G. Alexandros
Over the last 30 years, nanoparticle-based medicine has received tremendous attention due to its advances with smart therapeutics and less toxicity. Few nanomedicine products have been approved for commercial use in the clinic (such as Doxil®, Ambraxane®...). Nanomedicine research is still at its early...
09:51
Medicine by Sfakianakis G. Alexandros
Abstract An alternative method to control rice blast (Magnaporthe oryzae) is to include biological agent in the disease management strategy. The objective of this study was to assess the leaf blast-suppressing effects of rice phylloplane fungi. One Cladosporium sp. phylloplane fungus was shown to possess...
09:51
Medicine by Sfakianakis G. Alexandros
Cancer cachexia is a debilitating paraneoplastic wasting syndrome characterized by skeletal muscle depletion and unintentional weight loss. It affects up to 50-80% of patients with cancer and directly accounts for one-quarter of cancer-related deaths due to cardio-respiratory failure. Muscle weakness,...
09:51
Medicine by Sfakianakis G. Alexandros
Background: Heat shock proteins are powerful endogenous cytoprotective proteins which help cells to survive recurrent cellular stress events. Identifying the underlying molecular mechanisms and molecular targets is especially interesting since it may help to develop new therapeutic strategies for the...
09:51
Medicine by Sfakianakis G. Alexandros
Hydroxyproline is a non-essential amino acid found in collagen and few other extracellular animal proteins. It's two isomeric forms trans-4-hydroxy-L-proline and trans-3-hydroxy-L-proline play a crucial role in collagen synthesis and thermodynamic stability of the triple-helical conformation of collagen...
09:51
Medicine by Sfakianakis G. Alexandros
The immune response of the host tissue to the tested biomaterial predicts the success of implantation therapy success. Connective tissue cell line SaOS-2 and mononuclear cells isolated from "buffy coat" testing determines the overall immune response to the implanted biomaterial. Alginate hydrogel coatings...
09:51
Medicine by Sfakianakis G. Alexandros
Abstract Objectives The objective of the study was to assess the impact of periodontal crown lengthening surgery on clinical parameters at adjacent and non-adjacent sites compared to treated sites. Material and methods An electronic search was carried out on MEDLINE-PubMed, The Cochrane Library,...
09:51
Medicine by Sfakianakis G. Alexandros
Abstract Toxins produced by cyanobacteria in freshwater ecosystems constitute a serious health risk worldwide for humans that may use the affected water bodies for recreation, drinking water, and/or irrigation. Cyanotoxins have also been deemed responsible for loss of animal life in many places around...
09:51
Medicine by Sfakianakis G. Alexandros
In recent years, several small molecules approved by FDA for clinical studies are promising anti-cancer agent. Among the kinases, Abelson Leukaemia (Abl), sarcoma (Src), epidermal growth factor receptor (EGFR) and vascular endotelhial growth factor receptor (VEGFR) are considered as primary molecular...
09:51
Cancer by Sfakianakis G.Alexandros
Abstract Purpose Endometrial carcinoma is the most common gynecologic malignancy in both developed and some developing countries. Unlike cervical cancer, for which there is routine screening, only patients symptomatic for endometrial carcinoma...
09:51
Medicine by Sfakianakis G. Alexandros
Alterations of enzymes linked to arginine metabolism have been recently implicated in Alzheimer's disease (AD). Despite strong association of arginine changes with nitric oxide (NO) pathway, the impact of amyloid β (Aβ) peptides on arginine degradation and re-synthesis is unknown. In the present study...
09:51
Medicine by Sfakianakis G. Alexandros
Abstract As part of a research project, the concentrations of Cd, Cu, Pb, V, and Zn in the tissues of Styela plicata were investigated for the first time to determine if S. plicata is a suitable biological indicator for biomonitoring of heavy metals in eastern Aegean Sea coastal waters. To examine the...
09:51
Medicine by Sfakianakis G. Alexandros
Abstract Introduction The use of breast implants is on the rise due to increases in breast reconstructive and aesthetic surgery. Implant rupture is a possible complication. Among assessment modalities for implant rupture detection, MRI is considered the gold standard. Methods We conducted a prospective...
09:51
Cancer by Sfakianakis Alexandros
Abstract Purpose Endometrial carcinoma is the most common gynecologic malignancy in both developed and some developing countries. Unlike cervical cancer, for which there is routine screening, only patients symptomatic for endometrial carcinoma typically seek medical help for its diagnosis and treatment....
09:46
Head and Neck Diseases
Introduction: Cochlear implantation (CI) in subjects with unilateral profound sensorineural hearing loss was investigated. The authors of the present study demonstrated the binaural auditory outcomes in a 12- and 36-month prospective cohort outcome study. The present study aimed to do a long-term (LT)...
09:44
ΒιοΜηχανική
Publication date: Available online 10 August 2016Source:Nano Today Author(s): Abdul Rahim Ferhan, Dong-Hwan Kim Nanoparticle polymer composites have wide-ranging applications in fields such as catalysis, optoelectronics, drug delivery and biochemical sensing. In recent years, the use of noble metal...
09:43
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Introduction: Cochlear implantation (CI) in subjects with unilateral profound sensorineural hearing loss was investigated. The authors of the present study demonstrated the binaural auditory outcomes in a 12- and 36-month prospective cohort outcome study. The present study aimed to do a long-term...
09:42
Θεραπεία
Abstract Purpose The purpose of this study is to evaluate the pharmacokinetics, immunogenicity, safety, and tolerability of guselkumab, a human monoclonal antibody with high affinity and specificity for binding to interleukin-23. Methods In this first-in-human, phase 1, randomized study, a single...
09:42
Θεραπεία
Abstract Purpose Population pharmacokinetic analyses (PPK) have been used to establish bioequivalence for small molecules and some biologicals. We investigated whether PPK could also be useful in biosimilarity testing for monoclonal antibodies (MAbs). Methods Data from a biosimilarity trial with...
09:41
ΒιοΜηχανική
An organic–inorganic halide CH3NH3SnI3 perovskite with significantly improved structural stability is obtained via pressure-induced amorphization and recrystallization. In situ high-pressure resistance measurements reveal an increased electrical conductivity by 300% in the pressure-treated perovskite....
09:41
ΒιοΜηχανική
Publication date: 1 December 2016Source:Talanta, Volume 161 Author(s): Carmen Tejada-Casado, Maykel Hernández-Mesa, Monsalud del Olmo-Iruela, Ana M. García-Campaña A novel method for the analysis of benzimidazole residues in water samples by capillary electrochromatography-UV detection (290nm), using...
09:41
ΒιοΜηχανική
Publication date: 1 December 2016Source:Talanta, Volume 161 Author(s): R. Rapini, A. Cincinelli, G. Marrazza In this work, we propose an electrochemical DNA aptasensor for sensitive multidetection of acetamiprid based on a competitive format and disposable screen-printed arrays. To improve the sensitivity...
09:41
ΒιοΜηχανική
Publication date: 1 December 2016Source:Talanta, Volume 161 Author(s): Na Sai, Yuntang Wu, Guangui Yu, Zhong Sun, Guowei Huang A novel photonic crystal (PC) for the enrichment and detection of trace chloramphenicol (Cm) was constructed based on the combination of the imprinted crystalline colloidal...
09:41
ΒιοΜηχανική
Radiation pneumonitis is the most frequent acute pulmonary toxicity following stereotactic body radiation therapy for lung cancer. Here, we investigate clinical and dosimetric factors associated with symptomatic radiation pneumonitis in patients with stage I non–small cell lung cancer treated with stereotactic...
09:41
health683
Introduction: Cochlear implantation (CI) in subjects with unilateral profound sensorineural hearing loss was investigated. The authors of the present study demonstrated the binaural auditory outcomes in a 12- and 36-month prospective cohort outcome study. The present study aimed to do a long-term (LT)...
09:40
Θεραπεία
Abstract Molecular dynamics (MD) simulations and binding free energy calculations were employed to examine the interaction between E-selectin and six structurally-related oligosaccharides including the physiological ligand sialyl Lewis x (sLex). MD simulations revealed that sLex and its mimics share...
09:36
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Approximately 80% of patients with subclinical hypothyroidism (SCH) have TSH ≤ 10 mIU/L.1 Many of these subjects are treated with levothyroxine (L-T4) because they have anti-thyroperoxidase antibodies (TPOAb), goiter, high cardiovascular risk, dyslipidemia, depression, infertility, and symptoms of hypothyroidism....
09:36
medicinealexandrossfakianakis
Introduction: Cochlear implantation (CI) in subjects with unilateral profound sensorineural hearing loss was investigated. The authors of the present study demonstrated the binaural auditory outcomes in a 12- and 36-month prospective cohort outcome study. The present study aimed to do a long-term...
09:32
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Introduction: Cochlear implantation (CI) in subjects with unilateral profound sensorineural hearing loss was investigated. The authors of the present study demonstrated the binaural auditory outcomes in a 12- and 36-month prospective cohort outcome study. The present study aimed to do a long-term (LT)...
09:30
News in OtoRhinoLaryngology - Alexandros G. Sfakianakis
Introduction: Cochlear implantation (CI) in subjects with unilateral profound sensorineural hearing loss was investigated. The authors of the present study demonstrated the binaural auditory outcomes in a 12- and 36-month prospective cohort outcome study. The present study aimed to do a long-term (LT)...
09:27
otorhinolaryngologysfakianakis
Abstract Sleep complaints are reported by 40–60 % of menopausal women. Poor sleep is a risk factor for cardiovascular disease, diabetes, and obesity. The effect of menopausal hormone therapy on sleep quality is unclear. A systematic review and meta-analysis were conducted to summarize the efficacy of...
09:27
otorhinolaryngologysfakianakis
The vocal fold microflap technique is the ideal to remove benign vocal fold pathology. Our objective is to compare the amplitudes of the mucosal wave before and after the closure of microflap defect with fibrin glue, and when microflap is left to heal by secondary intention. from ! ORL via Alexandros...
09:27
otorhinolaryngologysfakianakis
Even though many studies have explored the problem of voice disorders among teachers worldwide, this problem is still not adequately studied in Egypt. The following study was conducted to investigate the risk factors of voice disorders among an Egyptian sample of school teachers, to measure the effect...
09:27
otorhinolaryngologysfakianakis
Vocal polyps do not have a well-defined therapeutic indication. The recommended treatment is often laryngeal microsurgery, followed by postoperative speech therapy. Speech therapy as the initial treatment for polyps is a new concept and aims to modify inappropriate vocal behavior, adjust the voice quality,...
09:27
otorhinolaryngologysfakianakis
High-pitched sung vowels may be considered phonetically “underspecified” because of (i) the tuning of the F1 to the f0 accompanying pitch raising and (ii) the wide harmonic spacing of the voice source resulting in the undersampling of the vocal tract transfer function. Therefore, sung vowel intelligibility...
09:27
otorhinolaryngologysfakianakis
We herein report the case of a patient presenting with myxofibrosarcoma (MFS) who underwent treatment with surgery, proton beam therapy (PBT), and pazopanib. A 64-year-old male was diagnosed with MFS, which ranged from the posterior neck to the shoulder. Surgery was performed as an initial treatment;...
09:26
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Approximately 80% of patients with subclinical hypothyroidism (SCH) have TSH ≤ 10 mIU/L.1 Many of these subjects are treated with levothyroxine (L-T4) because they have anti-thyroperoxidase antibodies (TPOAb), goiter, high cardiovascular risk, dyslipidemia, depression, infertility, and symptoms of hypothyroidism....
09:24
Oncology
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and is characterized by numerous genetic mutations. TNM staging is not sufficient for predicting patient outcomes. Additionally,...
09:24
Oncology
Abstract Background MicroRNA (miRNA) polymorphisms may alter miRNA-related processes, and they likely contribute to cancer susceptibility. Various studies have investigated the associations between genetic variants in several key...
09:24
Oncology
Purpose: To determine if BRAF and/or MEK inhibitor-induced GPNMB expression renders melanomas sensitive to CDX-011, an antibody-drug conjugate targeting GPNMB. Experimental Design: The TCGA melanoma dataset was interrogated for a panel of MITF-regulated melanosomal differentiation antigens, including...
09:24
Αισθητική Δερματολογία
Background Rosacea is a common chronic inflammatory disorder affecting facial skin. Currently, no accurate and objective method is available for assessing the severity of rosacea. Most studies use the National Rosacea Society Standard (NRSS) grading method, which lacks objectivity and yields varying...
09:23
medicinealexandrossfakianakis
Approximately 80% of patients with subclinical hypothyroidism (SCH) have TSH ≤ 10 mIU/L.1 Many of these subjects are treated with levothyroxine (L-T4) because they have anti-thyroperoxidase antibodies (TPOAb), goiter, high cardiovascular risk, dyslipidemia, depression, infertility, and symptoms of hypothyroidism....
09:23
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Approximately 80% of patients with subclinical hypothyroidism (SCH) have TSH ≤ 10 mIU/L.1 Many of these subjects are treated with levothyroxine (L-T4) because they have anti-thyroperoxidase antibodies (TPOAb), goiter, high cardiovascular risk, dyslipidemia, depression, infertility, and symptoms of hypothyroidism....
09:13
Anaesthesiology
Background and Objectives: Previously, we found that application of pulsed radiofrequency to a peripheral nerve injury induces changes in key genes regulating nociception concurrent with alleviation of paw sensitivity in an animal model. In the current study, we evaluated such genes after applying spinal...
09:13
Anaesthesiology
Objective: Erythromelalgia is a rare disorder associated with neuropathic pain that commonly affects the lower extremities. This pain is often refractory to multimodal treatment. Both pharmacologic management and interventional anesthetic blocks have been used with varying and often limited success....
09:12
Anaesthesiology
Objective: This report aimed to describe the characteristics and impact of subdural hematoma (SDH) after labor epidural analgesia. Case Reports: Eleven obstetric patients had SDHs associated with the use of labor epidural analgesia over 7 years at a tertiary care hospital. Ten of 11 patients had signs...
09:09
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
An organic–inorganic halide CH3NH3SnI3 perovskite with significantly improved structural stability is obtained via pressure-induced amorphization and recrystallization. In situ high-pressure resistance measurements reveal an increased electrical conductivity by 300% in the pressure-treated perovskite....
09:05
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Abstract Molecular dynamics (MD) simulations and binding free energy calculations were employed to examine the interaction between E-selectin and six structurally-related oligosaccharides including the physiological ligand sialyl Lewis x (sLex). MD simulations revealed that sLex and its mimics share...
09:05
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and is characterized by numerous genetic mutations. TNM staging is not sufficient for predicting patient outcomes. Additionally,...
09:05
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Abstract Background MicroRNA (miRNA) polymorphisms may alter miRNA-related processes, and they likely contribute to cancer susceptibility. Various studies have investigated the associations between genetic variants in several key...
09:01
Squamous cell carcinoma (SCC) - Cancer - Melanoma
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and is characterized by numerous genetic mutations. TNM staging is not sufficient for predicting patient outcomes. Additionally, ESCC shows poor responsiveness to chemotherapy and radiation. Thus,...
09:01
Squamous cell carcinoma (SCC) - Cancer - Melanoma
Abstract Background MicroRNA (miRNA) polymorphisms may alter miRNA-related processes, and they likely contribute to cancer susceptibility. Various studies have investigated the associations between genetic variants in several key miRNAs and the risk of human cancers; however, few studies have focused...
09:01
Squamous cell carcinoma (SCC) - Cancer - Melanoma
Purpose: To determine if BRAF and/or MEK inhibitor-induced GPNMB expression renders melanomas sensitive to CDX-011, an antibody-drug conjugate targeting GPNMB. Experimental Design: The TCGA melanoma dataset was interrogated for a panel of MITF-regulated melanosomal differentiation antigens, including...
08:57
Anaesthesiology
Summary Background An acceptable systolic or mean arterial blood pressure for children 0–6 years during anesthesia is unknown. Accepted blood pressures reported in standard charts for healthy awake children may not apply to those undergoing anesthesia. Aim Our goal was to define observed...
08:54
THERAPY MEDICINE BY SFAKIANAKIS G.ALEXANDROS
Abstract Molecular dynamics (MD) simulations and binding free energy calculations were employed to examine the interaction between E-selectin and six structurally-related oligosaccharides including the physiological ligand sialyl Lewis x (sLex). MD simulations revealed that sLex and its mimics share...
08:54
Oncology
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and is characterized by numerous genetic mutations. TNM staging is not sufficient for predicting patient outcomes. Additionally, ESCC shows poor responsiveness to chemotherapy and radiation. Thus,...
08:54
Oncology
Abstract Background MicroRNA (miRNA) polymorphisms may alter miRNA-related processes, and they likely contribute to cancer susceptibility. Various studies have investigated the associations between genetic variants in several key miRNAs and the risk of human cancers; however, few studies have focused...
08:54
Oncology
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and is characterized by numerous genetic mutations. TNM staging is not sufficient for predicting patient outcomes. Additionally, ESCC shows poor responsiveness to chemotherapy and radiation. Thus,...
08:54
Oncology
Abstract Background MicroRNA (miRNA) polymorphisms may alter miRNA-related processes, and they likely contribute to cancer susceptibility. Various studies have investigated the associations between genetic variants in several key miRNAs and the risk of human cancers; however, few studies have focused...
08:54
Oncology
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and is characterized by numerous genetic mutations. TNM staging is not sufficient for predicting patient outcomes. Additionally,...
08:54
Oncology
Abstract Background MicroRNA (miRNA) polymorphisms may alter miRNA-related processes, and they likely contribute to cancer susceptibility. Various studies have investigated the associations between genetic variants in several key...
08:54
Oncology
Purpose: To determine if BRAF and/or MEK inhibitor-induced GPNMB expression renders melanomas sensitive to CDX-011, an antibody-drug conjugate targeting GPNMB. Experimental Design: The TCGA melanoma dataset was interrogated for a panel of MITF-regulated melanosomal differentiation antigens, including...
08:54
Oncology
Abstract Purpose Avascular necrosis (AVN) of the femoral head is a major complication after internal fixation of a femoral neck fracture and determines the functional prognosis. We investigated postoperative bone single-photon emission...
08:54
Oncology
Purpose: To determine if BRAF and/or MEK inhibitor-induced GPNMB expression renders melanomas sensitive to CDX-011, an antibody-drug conjugate targeting GPNMB. Experimental Design: The TCGA melanoma dataset was interrogated for a panel of MITF-regulated melanosomal differentiation antigens, including...
08:54
Oncology
Abstract Purpose Avascular necrosis (AVN) of the femoral head is a major complication after internal fixation of a femoral neck fracture and determines the functional prognosis. We investigated postoperative bone single-photon emission computed tomography/computed tomography (SPECT/CT) for assessing...
08:54
Oncology
Purpose: To determine if BRAF and/or MEK inhibitor-induced GPNMB expression renders melanomas sensitive to CDX-011, an antibody-drug conjugate targeting GPNMB. Experimental Design: The TCGA melanoma dataset was interrogated for a panel of MITF-regulated melanosomal differentiation antigens, including...
08:54
Oncology
Abstract Purpose Avascular necrosis (AVN) of the femoral head is a major complication after internal fixation of a femoral neck fracture and determines the functional prognosis. We investigated postoperative bone single-photon emission...
08:54
Oncology
Purpose: To determine if BRAF and/or MEK inhibitor-induced GPNMB expression renders melanomas sensitive to CDX-011, an antibody-drug conjugate targeting GPNMB. Experimental Design: The TCGA melanoma dataset was interrogated for a panel of MITF-regulated melanosomal differentiation antigens, including...
08:54
Oncology
Abstract Purpose Avascular necrosis (AVN) of the femoral head is a major complication after internal fixation of a femoral neck fracture and determines the functional prognosis. We investigated postoperative bone single-photon emission computed tomography/computed tomography (SPECT/CT) for assessing...
08:51
Cancer by Sfakianakis G.Alexandros
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and is characterized by numerous genetic mutations. TNM staging is not sufficient for predicting patient outcomes. Additionally,...
08:51
Cancer by Sfakianakis G.Alexandros
Abstract Background MicroRNA (miRNA) polymorphisms may alter miRNA-related processes, and they likely contribute to cancer susceptibility. Various studies have investigated the associations between genetic variants in several key...
08:51
Cancer by Sfakianakis G.Alexandros
Purpose: To determine if BRAF and/or MEK inhibitor-induced GPNMB expression renders melanomas sensitive to CDX-011, an antibody-drug conjugate targeting GPNMB. Experimental Design: The TCGA melanoma dataset was interrogated for a panel of MITF-regulated melanosomal differentiation antigens, including...
08:42
OtoRhinoLaryngology by Sfakianakis G.Alexandros
A Retrospective Study of 440 Treatments in 100 Patients: Abstract Objective Frey’s syndrome is characterized as sweating, redness and warmth of the parotideal area and is often treated with botulinum toxin A. The objective of this retrospective study was to prove, whether the toxin dosage and time-to-treatment...
08:42
OtoRhinoLaryngology by Sfakianakis G.Alexandros
The Effects of Air Pollution on Asthma Hospital Admissions in Adelaide, South Australia, 2003–2013: Time-Series and Case-crossover Analyses: Abstract Background Air pollution can have adverse health effects on asthma sufferers, but the effects vary with geographic, environmental and population...
08:42
OtoRhinoLaryngology by Sfakianakis G.Alexandros
sIgE Ana o 1, 2 and 3 accurately distinguish tolerant from allergic children sensitised to cashew nuts: Abstract Background The double-blind, placebo-controlled food challenge test (DBPCFC) is the gold standard in cashew nut allergy. This test is costly, time-consuming and not without side effects....
08:41
health683
The Effects of Air Pollution on Asthma Hospital Admissions in Adelaide, South Australia, 2003–2013: Time-Series and Case-crossover Analyses: Abstract Background Air pollution can have adverse health effects on asthma sufferers, but the effects vary with geographic, environmental and population characteristics....
08:41
health683
A Retrospective Study of 440 Treatments in 100 Patients: Abstract Objective Frey’s syndrome is characterized as sweating, redness and warmth of the parotideal area and is often treated with botulinum toxin A. The objective of this retrospective study was to prove, whether the toxin dosage and time-to-treatment...
08:41
health683
sIgE Ana o 1, 2 and 3 accurately distinguish tolerant from allergic children sensitised to cashew nuts: Abstract Background The double-blind, placebo-controlled food challenge test (DBPCFC) is the gold standard in cashew nut allergy. This test is costly, time-consuming and not without side effects....
08:41
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
On the cover: The cover image, by Hamish Scott et al., is based on the Research Article Ectrodactyly and Lethal Pulmonary Acinar Dysplasia Associated with Homozygous FGFR2 Mutations Identified by Exome Sequencing, Pages 955–963, DOI: 10.1002/humu.23032. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis...
08:41
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2aQvmV6 via IFTTT
08:40
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2bmiwSD via IFTTT
08:40
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2aQv4xI via IFTTT
08:40
Cancer
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and is characterized by numerous genetic mutations. TNM staging is not sufficient for predicting patient outcomes. Additionally, ESCC shows poor responsiveness to chemotherapy and radiation. Thus,...
08:40
Cancer
Abstract Background MicroRNA (miRNA) polymorphisms may alter miRNA-related processes, and they likely contribute to cancer susceptibility. Various studies have investigated the associations between genetic variants in several key miRNAs and the risk of human cancers; however, few studies have focused...
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