Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τρίτη 16 Αυγούστου 2016

OtoRhinoLaryngology & Medicine,New Articles,August 17th,2016


Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Process Mapping With Times, Process Measures, and Labor Costs Editorial
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Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Chemically modified titanium–zirconium implants in comparison with commercially pure titanium controls stimulate the early molecular pathways of bone healing
Abstract Objectives Titanium–zirconium (TiZr) has been proposed as a mechanically stronger alternative to commercially pure titanium for oral and orthopaedic implants. However, not much is known on the osseointegration kinetics of TiZr surfaces. In this study, we aimed to identify the genetic response...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Dynamic Assessment of Value During High-Cost Cancer Treatment: A Response to American Society of Clinical Oncology and European Society of Medical Oncology Editorial
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Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Improving the Quality and Value of Cancer Care: A Work in Progress–The 2016 Joseph V. Simone Award and Lecture Editorial
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Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Association of Practice-Level Hospital Use With End-of-Life Outcomes, Readmission, and Weekend Hospitalization Among Medicare Beneficiaries With Cancer Original Contribution
Purpose: To determine the relationships between hospital use of treating oncology practices and patient outcomes. Patients and Methods: Retrospective analysis of 397,646 Medicare beneficiaries who received anticancer therapy in 2012. Each beneficiary was associated with a practice; practices were...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
CancerLinQ Update Presentation Summary
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Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Overcoming the Implementation Gap in Multidisciplinary Oncology Care Programs Editorial
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Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
What Adult Cancer Care Can Learn From Pediatrics Editorial
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Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Improving Oral Oncolytic Patient Self-Management Quality in Action
Purpose: Managing patients who are taking oral oncolytics is challenging because of the changing paradigm from frequent supervision during intravenous therapy to periodic observation with oral administration of drugs. We joined the Michigan Oncology Quality Consortium (MOQC) Oral Oncolytics Collaborative...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Four Years Running: The ASCO Quality Care Symposium Foreword
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Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Defining High-Quality Palliative Care in Oncology Practice: An American Society of Clinical Oncology/American Academy of Hospice and Palliative Medicine Guidance Statement Care Delivery
Purpose: Integrated into routine oncology care, palliative care can improve symptom burden, quality of life, and patient and caregiver satisfaction. However, not all oncology practices have access to specialist palliative medicine. This project endeavored to define what constitutes high-quality primary...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Prevalence of Medical Conditions Potentially Amenable to Cellular Therapy among Families Privately Storing Umbilical Cord Blood
Abstract Introduction Little is known about the prevalence of conditions potentially amenable to cellular therapy among families storing umbilical cord blood in private cord blood banks. Methods A cross-sectional study of families with at least one child who stored umbilical cord blood in the largest...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
National Initiatives to Improve Systems for Postpartum Care
Abstract Purpose To showcase several current national initiatives that focus on reducing maternal mortality and severe maternal morbidity and promote postpartum health and wellness for all women. Description Maternal injuries and deaths are a serious public health concern with tremendous impact on families,...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Attitudes and Decision Making Related to Pregnancy Among Young Women with Cystic Fibrosis
Abstract Introduction The number of female patients with CF able to consider pregnancy has increased with improved therapies. This study explored attitudes and decision making regarding pregnancy among young women with CF. Methods Twenty-two women with CF ages 18–30 years completed semi-structured,...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Prevalence of Perinatal Depression in the Military: A Systematic Review of the Literature
Abstract Objectives Perinatal depression (PND) has been widely studied in the general population, but has been under studied in military populations. This literature review evaluates studies of PND in military service women and spouses of military servicemen. Methods Articles from peer-reviewed journals...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Reassessing the Association between WIC and Birth Outcomes Using a Fetuses-at-Risk Approach
Abstract Objectives Women with longer, healthier pregnancies have more time to enroll in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), biasing associations between WIC and birth outcomes. We examined the association between WIC and preterm birth (PTB), low birth...
OtoRhinoLaryngology
Role of Facial Nerve Motor-Evoked Potential Ratio in Predicting Facial Nerve Function in Vestibular Schwannoma Surgery Both Immediate and at 1 Year
Role of Facial Nerve Motor-Evoked Potential Ratio in Predicting Facial Nerve Function in Vestibular Schwannoma Surgery Both Immediate and at 1 Year:Objective: To determine whether transcranial electrical stimulation-induced facial motor-evoked potential (FMEP) monitoring of the facial nerve (FN) during...
OtoRhinoLaryngology
Surgery and Chemoradiotherapy for Temporal Bone Cancer
The Outcomes of Objective: We aimed to evaluate the prognostic factors and efficacy of treatment modalities for patients with temporal bone cancer, and to determine if definitive chemoradiotherapy (CRT) for advanced-stage disease can provide a substitute for highly invasive surgeries.Study Design: Retrospective...
OtoRhinoLaryngology
Modification of Osseointegrated Device Parameters to Improve Speech in Noise and Localization Ability: Clinical Recommendations
Modification of Osseointegrated Device Parameters to Improve Speech in Noise and Localization Ability: Clinical Recommendations: Objective: To determine how best to modify osseointegrated (OI) devices or environmental settings to maximize hearing performance.Study Design: Prospective cohort study.Setting:...
OtoRhinoLaryngology
Revision Surgery for Superior Canal Dehiscence Syndrome
Revision Surgery for Superior Canal Dehiscence Syndrome:Objective: To identify factors associated with surgical failure for superior canal dehiscence syndrome (SCDS) and define rates of complications and cure after revision SCDS repair.Study Design: Retrospective patient series.Setting: Tertiary care...
OtoRhinoLaryngology
An Easy and Reliable Method to Locate the Dehiscence During Middle Fossa Superior Canal Dehiscence Surgery: The horizontal distance from the outer cortex of the squama temporalis to the SSCD consistently approximates 1 inch. This easily remembered distance can aid surgeons in locating or confirming the SSCD during middle fossa surgery.
It is a ©inch: Objective: The middle fossa floor lacks reliable surface landmarks. In cases of superior semicircular canal dehiscence (SSCD), multiple skull base defects may be present, further confounding the location of the labyrinth. Misidentification of the SSCD during surgery may lead to treatment...
OtoRhinoLaryngology
Discovering Menière's Disease and Its Association With Migraine Headaches
A Historical RecountObjectives: In evaluating the historical context of the first description of Menière’s disease, its association with migraine headaches is compelling. We have outlined the events and observations of Prosper Menière, which led him to establish a link between migraine headaches and...
OtoRhinoLaryngology
Correlation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness Handicap
 Otology & Neurotology:September 2016 - Volume 37 - Issue 8 - p 1104–1110doi: 10.1097/MAO.0000000000001126Vestibular DisordersCorrelation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness HandicapHunter, Jacob B.; O’Connell,...
OtoRhinoLaryngology
Labyrinthine 3D-FLAIR Abnormalities in Idiopathic Sudden Sensorineural Hearing Loss.
Prognostic Value of AJNR Am J Neuroradiol. 2016 Aug ;Authors: Lee JI, Yoon RG, Lee JH, Park JW, Yoo MH, Ahn JH, Chung JW, Park HJAbstract BACKGROUND AND PURPOSE: According to recent research, modern MR imaging can detect the presense of abnormalities on labyrinthine. Our aim was to report the...
OtoRhinoLaryngology
Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor
Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor: The standard method to determine the output level of acoustic and mechanical stimulation to the inner ear is measurement of vibration response of the stapes in human cadaveric temporal bones (TBs)...
OtoRhinoLaryngology
Atlantoaxial rotatory fixation (AARF)
Chronic neglected irreducible atlantoaxial rotatory subluxation in adolescence: Pravin PadalkarJournal of Craniovertebral Junction and Spine 2016 7(3):184-188Atlantoaxial rotatory fixation (AARF) is a rare condition and delayed diagnosis. We report a case of chronic neglected atlantoaxial rotatory subluxation...
OtoRhinoLaryngology
Micro CT visualization of silver nanoparticles in the middle and inner ear of rat and transportation pathway after transtympanic injection.
J Nanobiotechnology.Authors: Zou J, Hannula M, Misra S, Feng H, Labrador RH, Aula AS, Hyttinen J, Pyykkö IAbstract BACKGROUND: Silver nanoparticles (Ag NPs) displayed strong activities in anti-bacterial, anti-viral, and anti-fungal studies and were reportedly efficient in treating otitis media....
OtoRhinoLaryngology
Cervical vertebral maturation (CVM)
Morphological comparison of cervical vertebrae in adult females with different sagittal craniofacial patterns: A cross-sectional study: Ozer Alkan, Cihan Aydogan, Sevil AkkayaJournal of Craniovertebral Junction and Spine 2016 7(3):135-139Introduction: Cervical vertebral maturation (CVM) methods have...
OtoRhinoLaryngology
Neglected dislocation in sub-axial cervical spine
Case series and a suggested treatment protocol: Sudhir Kumar Srivastava, Rishi Anil Aggarwal, Sunil Krishna Bhosale, Pradip Sharad NemadeJournal of Craniovertebral Junction and Spine 2016 7(3):140-145Context: Approaches suggested for treatment of neglected dislocations in the subaxial cervical spine...
OtoRhinoLaryngology
Proposed clinical internal carotid artery classification system
Proposed clinical internal carotid artery classification system: Saleem I Abdulrauf, Ahmed M Ashour, Eric Marvin, Jeroen Coppens, Brian Kang, Tze Yu Yeh Hsieh, Breno Nery, Juan R Penanes, Aysha K Alsahlawi, Shawn Moore, Hussam Abou Al-Shaar, Joanna Kemp, Kanika Chawla, Nanthiya Sujijantarat, Alaa Najeeb,...
OtoRhinoLaryngology
Pure spinal epidural cavernous hemangiomas (PSECHs)
Pure spinal epidural cavernous hemangioma: A case series of seven cases: Ignatius Ngene Esene, Ahmed M Ashour, Eric Marvin, Mohamed Nosseir, Zeiad Y Fayed, Khaled Seoud, Khaled El BahyJournal of Craniovertebral Junction and Spine 2016 7(3):176-183Introduction: Pure spinal epidural cavernous hemangiomas...
health683
Oncologic Free Fibula Flap Mandible Reconstruction
Miniplates Versus Reconstruction Bars for Oncologic Free Fibula Flap Mandible Reconstruction: Purpose: The free fibula is the flap of choice for reconstructing most segmental mandibular defects resulting from head and neck resections. The use of miniplates or reconstruction bars for fixation has been...
health683
Systematic Reviews in Craniofacial Trauma
—Strengths and Weaknesses: Background: Despite substantial advances in the management of craniofacial trauma, numerous clinical questions remain. These are increasingly being answered using systematic reviews (SRs). However, caution is warranted as their validity and role in influencing clinical practice...
health683
Biomarkers in Occupational Asthma
Biomarkers in Occupational Asthma: Abstract Purpose of Review Work-related asthma is a common disorder among adult asthma patients, and in the case of occupational asthma, it is induced by workplace exposures. Recent Findings Occupational asthma provides an excellent model and benchmark for identifying...
health683
Alpha-Gal Allergy : The syndrome of delayed allergic reactions to the carbohydrate galactose-alpha-1,3-galactose (“alpha-gal”)
Invited Commentary: Alpha-Gal Allergy: Tip of the Iceberg to a Pivotal Immune Response: Abstract The syndrome of delayed allergic reactions to the carbohydrate galactose-alpha-1,3-galactose (“alpha-gal”) has become increasingly recognized in allergy and immunology clinics regionally throughout the...
health683
Innate Immune Responses to Fungal Allergens
Innate Immune Responses to Fungal Allergens: Abstract Purpose of Review In this review, we describe innate immunity to fungi and the ability of pattern recognition receptors (PRRs) to recognize fungal-associated molecular patterns (FAMPs) and danger-associated molecular patterns (DAMPs). Recent...
health683
Climate change, air pollution, and allergic respiratory diseases
: an update.: Purpose of review: The rising trend in prevalence of allergic respiratory disease and bronchial asthma, observed over the last decades, can be explained by changes occurring in the environment, with increasing presence of biologic, such as allergens, and chemical atmospheric trigger factors...
health683
Allergy prevention by breastfeeding: possible mechanisms and evidence from human cohorts.
Allergy prevention by breastfeeding: possible mechanisms and evidence from human cohorts.: Purpose of review: Allergy is a modern disease which does not seem to benefit from breast milk preventive effects. We propose that maternal milk composition has not adapted to the needs of allergy prevention because...
health683
Host genetics affect microbial ecosystems via host immunity.
Host genetics affect microbial ecosystems via host immunity.: Purpose of review: Genetic evolution of multicellular organisms has occurred in response to environmental challenges, including competition for nutrients, climate change, physical and chemical stressors, and pathogens. However, fitness of...
health683
Allergic manifestations of contact lens wearing.
Allergic manifestations of contact lens wearing.: Purpose of review: Contact lens-induced papillary conjunctivitis (CLPC) is a common ocular allergic disease in contact lens wearers. In its more severe form, it can cause giant papillary conjunctivitis, resulting in contact lens intolerance and the need...
health683
Ocular allergy.
An update on .: Purpose of Review: The update reviews prevalence, classification, cause, and treatment options for allergic eye disease. Recent Findings: The incidence of allergic eye disease is underreported but may affect almost all patients with allergic rhinitis. Increased rates of oculonasal symptoms...
health683
Environmental biodiversity protecting from allergy.
The rich and the poor: Purpose of review: It has been proposed that biodiversity loss leads to reduced interaction between environmental and human microbiotas. This, in turn, may lead to immune dysfunction and impaired tolerance mechanisms in humans. That is, contact with environmental biodiversity is...
health683
Epidemiology of severe anaphylaxis
can we use population-based data to understand anaphylaxis?.: Purpose of review: The observed increase in incidence of allergic disease in many regions over the past 3 decades has intensified interest in understanding the epidemiology of severe allergic reactions. We discuss the issues in collecting...
health683
Understanding and treatment of allergic skin diseases.
The ‘omics’ revolution: redefining the understanding and treatment of allergic skin diseases.: Purpose of review: To evaluate how the genomic, transcriptomic, and proteomic profiles of allergic skin diseases, like atopic dermatitis and allergic contact dermatitis, contribute to their understanding and...
health683
Asymmetrical Hearing Loss in Cases of Industrial Noise Exposure
A Systematic Review of the Literature: Objective: Asymmetrical hearing thresholds are common in people claiming compensation for noise-induced hearing loss (NIHL). When present and otherwise unexplained, there is some controversy as to whether such asymmetry can be attributed to occupational noise exposure....
health683
Atopic dermatitis: new evidence on the role of allergic inflammation.
Atopic dermatitis: new evidence on the role of allergic inflammation.: Purpose of review: Atopic dermatitis is a chronic relapsing inflammatory skin disease. In the presence of a complex genetic background, there is increasing evidence for the role of specific allergenic trigger factors in perpetuating...
health683
Facial Nerve Disorders and Diseases: Diagnosis and Management: Orlando Guntinas-Lichius and Barry M. Schaitkin; Stuttgart: Thieme, 2015.
Facial Nerve Disorders and Diseases: Diagnosis and Management: Orlando Guntinas-Lichius and Barry M. Schaitkin; Stuttgart: Thieme, 2015.: http://ift.tt/2b3dNBu
health683
Interleukin-17 and the interleukin-20 family in inflammatory allergic skin diseases.
A systematic review of the role of : Purpose of review: Allergic skin diseases include atopic dermatitis/eczema, contact dermatitis, and drug hypersensitivity. Allergic skin diseases have a high prevalence. Atopic dermatitis is one of the most common inflammatory skin diseases and similar for allergic...
health683
Introduction to the Pharmaceutical Interventions for Hearing Loss Clinical Research Guidance Papers
Introduction to the Pharmaceutical Interventions for Hearing Loss Clinical Research Guidance Papers: http://ift.tt/2bFt5Aq

health683
The Impact of Electrode Array Length on Hearing Preservation in Cochlear Implantation
The Impact of Electrode Array Length on Hearing Preservation in Cochlear Implantation: Objective: The aim of the study was to determine the degree of hearing preservation (HP) and its relation to electrode array length after cochlear implantation using different thin flexible electrode arrays (TFEA)....
health683
Electrode Location and Angular Insertion Depth Are Predictors of Audiologic Outcomes in Cochlear Implantation
Otology & Neurotology:September 2016 – Volume 37 – Issue 8 – p 1016–1023 doi: 10.1097/MAO.0000000000001125 Cochlear Implants Electrode Location and Angular Insertion Depth Are Predictors of Audiologic Outcomes in Cochlear Implantation O’Connell, Brendan P.; Cakir, Ahmet; Hunter, Jacob B.; Francis,...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Dynamic Assessment of Value During High-Cost Cancer Treatment: A Response to American Society of Clinical Oncology and European Society of Medical Oncology [Editorial]
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OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Improving the Quality and Value of Cancer Care: A Work in Progress--The 2016 Joseph V. Simone Award and Lecture [Editorial]
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OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Association of Practice-Level Hospital Use With End-of-Life Outcomes, Readmission, and Weekend Hospitalization Among Medicare Beneficiaries With Cancer [Original Contribution]
Purpose:To determine the relationships between hospital use of treating oncology practices and patient outcomes.Patients and Methods:Retrospective analysis of 397,646 Medicare beneficiaries who received anticancer therapy in 2012. Each beneficiary was associated with a practice; practices were ranked...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
CancerLinQ Update [Presentation Summary]
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OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Overcoming the Implementation Gap in Multidisciplinary Oncology Care Programs [Editorial]
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OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
What Adult Cancer Care Can Learn From Pediatrics [Editorial]
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OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Process Mapping With Times, Process Measures, and Labor Costs [Editorial]
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OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Improving Oral Oncolytic Patient Self-Management [Quality in Action]
Purpose:Managing patients who are taking oral oncolytics is challenging because of the changing paradigm from frequent supervision during intravenous therapy to periodic observation with oral administration of drugs. We joined the Michigan Oncology Quality Consortium (MOQC) Oral Oncolytics Collaborative...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Four Years Running: The ASCO Quality Care Symposium [Foreword]
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OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Defining High-Quality Palliative Care in Oncology Practice: An American Society of Clinical Oncology/American Academy of Hospice and Palliative Medicine Guidance Statement [Care Delivery]
Purpose:Integrated into routine oncology care, palliative care can improve symptom burden, quality of life, and patient and caregiver satisfaction. However, not all oncology practices have access to specialist palliative medicine. This project endeavored to define what constitutes high-quality primary...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Current Status and Future of Skin Substitutes for Chronic Wound Healing
Chronic wounds, including diabetic ulcers, pressure ulcers, venous ulcers, and arterial insufficiency ulcers, are both difficult and expensive to treat. Conventional wound care may sometimes lead to suboptimal wound healing and significant morbidity and mortality for patients. The use of skin substitutes...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Higher Risk of Ischemic Events in Secondary Prevention for Patients With Persistent Than Those With Paroxysmal Atrial Fibrillation [Original Contribution]
Background and Purpose—The discrimination between paroxysmal and sustained (persistent or permanent) atrial fibrillation (AF) has not been considered in the approach to secondary stroke prevention. We aimed to assess the differences in clinical outcomes between mostly anticoagulated patients with sustained...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Increased Frontal Lobe Activation After Aneurysmal Subarachnoid Hemorrhage [Original Contribution]
Background and Purpose—Neurocognitive deficits are common among survivors of aneurysmal subarachnoid hemorrhage, even among those with good outcomes and no structural lesions. This study aims to probe the neurophysiological underpinnings of cognitive dysfunction among patients with ruptured intracranial...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Vascular Tortuosity May Be Associated With Cervical Artery Dissection [Original Contribution]
Background and Purpose—Dissection is an increasingly recognized cause of ischemic stroke, which occurs spontaneously or after trauma, in relatively young patients. We hypothesized that there might be a predisposing factor weakening the vascular wall and that arterial tortuosity might be higher in patients...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Electrode Location and Angular Insertion Depth Are Predictors of Audiologic Outcomes in Cochlear Implantation
Otology & Neurotology: September 2016 – Volume 37 – Issue 8 – p 1016–1023 doi: 10.1097/MAO.0000000000001125 Cochlear Implants Electrode Location and Angular Insertion Depth Are Predictors of Audiologic Outcomes in Cochlear Implantation O’Connell, Brendan P.; Cakir, Ahmet; Hunter, Jacob...
medicinealexandrossfakianakis
Allergic manifestations of contact lens wearing.
Allergic manifestations of contact lens wearing.: Purpose of review: Contact lens-induced papillary conjunctivitis (CLPC) is a common ocular allergic disease in contact lens wearers. In its more severe form, it can cause giant papillary conjunctivitis, resulting in contact lens intolerance and the need...
medicinealexandrossfakianakis
Environmental biodiversity protecting from allergy.
The rich and the poor:  Purpose of review: It has been proposed that biodiversity loss leads to reduced interaction between environmental and human microbiotas. This, in turn, may lead to immune dysfunction and impaired tolerance mechanisms in humans. That is, contact with environmental biodiversity...
OroFacial Medicine by Alexandros G.Sfakianakis
“Enhanced bioadhesivity of dopamine-functionalized polysaccharidic membranes for general surgery applications”
Publication date: Available online 16 August 2016Source:Acta BiomaterialiaAuthor(s): F. Scognamiglio, A. Travan, M. Borgogna, I. Donati, E. Marsich, J.W.A.M. Bosmans, L. Perge, M.P. Foulc, N.D. Bouvy, S. PaolettiAn emerging strategy to improve adhesiveness of biomaterials in wet conditions takes inspiration...
medicinealexandrossfakianakis
Ocular allergy.
An update on .: Purpose of Review: The update reviews prevalence, classification, cause, and treatment options for allergic eye disease. Recent Findings: The incidence of allergic eye disease is underreported but may affect almost all patients with allergic rhinitis. Increased rates of oculonasal symptoms...
medicinealexandrossfakianakis
Epidemiology of severe anaphylaxis
can we use population-based data to understand anaphylaxis?.: Purpose of review: The observed increase in incidence of allergic disease in many regions over the past 3 decades has intensified interest in understanding the epidemiology of severe allergic reactions. We discuss the issues in collecting...
medicinealexandrossfakianakis
Understanding and treatment of allergic skin diseases.
The ‘omics’ revolution: redefining the understanding and treatment of allergic skin diseases.: Purpose of review: To evaluate how the genomic, transcriptomic, and proteomic profiles of allergic skin diseases, like atopic dermatitis and allergic contact dermatitis, contribute to their understanding and...
medicinealexandrossfakianakis
Interleukin-17 and the interleukin-20 family in inflammatory allergic skin diseases.
A systematic review of the role of  : Purpose of review: Allergic skin diseases include atopic dermatitis/eczema, contact dermatitis, and drug hypersensitivity. Allergic skin diseases have a high prevalence. Atopic dermatitis is one of the most common inflammatory skin diseases and similar for allergic...
medicinealexandrossfakianakis
Atopic dermatitis: new evidence on the role of allergic inflammation.
Atopic dermatitis: new evidence on the role of allergic inflammation.: Purpose of review: Atopic dermatitis is a chronic relapsing inflammatory skin disease. In the presence of a complex genetic background, there is increasing evidence for the role of specific allergenic trigger factors in perpetuating...
medicinealexandrossfakianakis
Asymmetrical Hearing Loss in Cases of Industrial Noise Exposure
A Systematic Review of the Literature: Objective: Asymmetrical hearing thresholds are common in people claiming compensation for noise-induced hearing loss (NIHL). When present and otherwise unexplained, there is some controversy as to whether such asymmetry can be attributed to occupational noise...
medicinealexandrossfakianakis
Facial Nerve Disorders and Diseases: Diagnosis and Management: Orlando Guntinas-Lichius and Barry M. Schaitkin; Stuttgart: Thieme, 2015.
Facial Nerve Disorders and Diseases: Diagnosis and Management: Orlando Guntinas-Lichius and Barry M. Schaitkin; Stuttgart: Thieme, 2015.: http://ift.tt/2b3dNBu
medicinealexandrossfakianakis
The Impact of Electrode Array Length on Hearing Preservation in Cochlear Implantation
The Impact of Electrode Array Length on Hearing Preservation in Cochlear Implantation: Objective: The aim of the study was to determine the degree of hearing preservation (HP) and its relation to electrode array length after cochlear implantation using different thin flexible electrode arrays (TFEA)....
medicinealexandrossfakianakis
Introduction to the Pharmaceutical Interventions for Hearing Loss Clinical Research Guidance Papers
Introduction to the Pharmaceutical Interventions for Hearing Loss Clinical Research Guidance Papers: http://ift.tt/2bFt5Aq
medicinealexandrossfakianakis
Electrode Location and Angular Insertion Depth Are Predictors of Audiologic Outcomes in Cochlear Implantation
Otology & Neurotology: September 2016 – Volume 37 – Issue 8 – p 1016–1023 doi: 10.1097/MAO.0000000000001125 Cochlear Implants Electrode Location and Angular Insertion Depth Are Predictors of Audiologic Outcomes in Cochlear Implantation O’Connell, Brendan P.; Cakir, Ahmet; Hunter, Jacob...
Head and Neck Diseases
Serial Monitoring of Otoacoustic Emissions
 in Clinical Trials: The purpose of this report is to provide guidance on the use of otoacoustic emissions (OAEs) as a clinical trial outcome measure for pharmaceutical interventions developed to prevent acquired hearing loss secondary to cochlear insult. OAEs are a rapid, noninvasive measure...
Head and Neck Diseases
Temporal Lobe Gliosarcoma After Gamma Knife Radiosurgery for Vestibular Schwannoma
Temporal Lobe Gliosarcoma After Gamma Knife Radiosurgery for Vestibular Schwannoma: Objective: Secondary tumorigenesis after exposure to ionizing radiation is a well-described phenomenon. The probability of developing a malignancy after stereotactic radiosurgery (SRS) is theoretically less than...
Head and Neck Diseases
Cochlear Implantation and Deaf Education
Moving Beyond GDP: Cost Effectiveness of Cochlear Implantation and Deaf Education in Latin America: Hypothesis: Cochlear implantation (CI) and deaf education are cost effective management strategies of childhood profound sensorineural hearing loss in Latin America. Background: CI has been widely established...
Head and Neck Diseases
Vestibular Schwannomas: Do Linear and Volumetric Parameters on MRI Correlate With Hearing Loss?
Otology & Neurotology: September 2016 - Volume 37 - Issue 8 - p 1168–1173 doi: 10.1097/MAO.0000000000001150 Tumors of the Ear and Cranial Base Vestibular Schwannomas: Do Linear and Volumetric Parameters on MRI Correlate With Hearing Loss? Bathla, Girish; Case, Brendan M.; Berbaum, Kevin;...
Head and Neck Diseases
Ototopical Antibiotics,ciprofloxacin-dexamethasone (CD), ofloxacin (OF), and Cortisporin (CS)
Otology & Neurotology: September 2016 - Volume 37 - Issue 8 - p 1049–1054 doi: 10.1097/MAO.0000000000001115 Middle Ear and Mastoid Disease National Utilization and Forecasting of Ototopical Antibiotics: Medicaid Data Versus "Dr. Google" Crowson, Matthew G.; Schulz, Kristine; Tucci, Debara...
Head and Neck Diseases
Idiopathic Upper Extremity Paresis Following Middle Cranial Fossa Resection of a Vestibular Schwannoma
Parsonage–Turner Syndrome: A Case of    Objective: In this patient report, Parsonage–Turner syndrome (acute brachial neuropathy) developed in our patient 1 day after resection of a vestibular schwannoma by a middle cranial fossa approach. Aiming to increase awareness of this rare disorder among neurotologists,...
Head and Neck Diseases
Bilateral Petrous Apex Cephaloceles and Skull Base Attenuation in Setting of Idiopathic Intracranial Hypertension
Bilateral Petrous Apex Cephaloceles and Skull Base Attenuation in Setting of Idiopathic Intracranial Hypertension:   http://ift.tt/2blY2J7 OtoRhinoLaryngology by Alexandros G. Sfakianakis
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Oncologic Free Fibula Flap Mandible Reconstruction
Miniplates Versus Reconstruction Bars for Oncologic Free Fibula Flap Mandible Reconstruction: Purpose: The free fibula is the flap of choice for reconstructing most segmental mandibular defects resulting from head and neck resections. The use of miniplates or reconstruction bars for fixation has been...
Head and Neck Diseases
Oxidative Damage and Inflammation Biomarkers: Strategy in Hearing Disorders
Oxidative Damage and Inflammation Biomarkers: Strategy in Hearing Disorders: Importance: Excess free radical-induced oxidative stress and inflammatory processes are increasingly recognized as causative factors in hearing and balance disorders. Antioxidant micronutrients neutralize free radicals and,...
Head and Neck Diseases
The Management of Pediatric Unilateral Sensorineural Hearing Loss
The Yield of Multigene Testing in  Objective: To explore the role and yield of multigene evaluation in children recently diagnosed with unilateral sensori-neural hearing loss (SNHL). Study Design: Retrospective cohort study. Setting: Tertiary level pediatric institution. Patients: Sixty children...
Head and Neck Diseases
Vestibular Impairment in Dementia
Vestibular Impairment in Dementia: Objective: Recent studies suggest an association between vestibular and cognitive function. The goal of the study was to investigate whether vestibular function was impaired in individuals with mild cognitive impairment (MCI) and Alzheimer's disease (AD) compared with...
Head and Neck Diseases
Transcanal Endoscopic Ear Surgery for the Management of Congenital Ossicular Fixation
Transcanal Endoscopic Ear Surgery for the Management of Congenital Ossicular Fixation: Objectives: 1) To describe the technique for transcanal endoscopic management of congenital ossicular chain fixation. 2) To highlight the utility and outcomes of the endoscopic approach for management of congenital...
Head and Neck Diseases
Risk Assessment and Prevention of Corneal Complications After Lateral Skull Base Surgery
Risk Assessment and Prevention of Corneal Complications After Lateral Skull Base Surgery: Objective: To analyze the rate of corneal complications after lateral skull base surgery, and the relative risk of each potential contributing factor. Study Design: Retrospective cohort study. Setting: Tertiary...
Head and Neck Diseases
Stability, Survival, and Tolerability of an Auditory Osseointegrated Implant for Bone Conduction Hearing: Long-Term Follow-Up of a Randomized Controlled Trial
Otology & Neurotology: September 2016 - Volume 37 - Issue 8 - p 1077–1083 doi: 10.1097/MAO.0000000000001111 Prosthetic Devices Stability, Survival, and Tolerability of an Auditory Osseointegrated Implant for Bone Conduction Hearing: Long-Term Follow-Up of a Randomized Controlled Trial ...
Head and Neck Diseases
Role of Facial Nerve Motor-Evoked Potential Ratio in Predicting Facial Nerve Function in Vestibular Schwannoma Surgery Both Immediate and at 1 Year
Role of Facial Nerve Motor-Evoked Potential Ratio in Predicting Facial Nerve Function in Vestibular Schwannoma Surgery Both Immediate and at 1 Year: Objective: To determine whether transcranial electrical stimulation-induced facial motor-evoked potential (FMEP) monitoring of the facial nerve (FN) during...
Head and Neck Diseases
Modification of Osseointegrated Device Parameters to Improve Speech in Noise and Localization Ability: Clinical Recommendations
Modification of Osseointegrated Device Parameters to Improve Speech in Noise and Localization Ability: Clinical Recommendations: Objective: To determine how best to modify osseointegrated (OI) devices or environmental settings to maximize hearing performance. Study Design: Prospective cohort...
Head and Neck Diseases
Surgery and Chemoradiotherapy for Temporal Bone Cancer
The Outcomes of  Objective: We aimed to evaluate the prognostic factors and efficacy of treatment modalities for patients with temporal bone cancer, and to determine if definitive chemoradiotherapy (CRT) for advanced-stage disease can provide a substitute for highly invasive surgeries. Study Design:...
Head and Neck Diseases
An Easy and Reliable Method to Locate the Dehiscence During Middle Fossa Superior Canal Dehiscence Surgery: The horizontal distance from the outer cortex of the squama temporalis to the SSCD consistently approximates 1 inch. This easily remembered distance can aid surgeons in locating or confirming the SSCD during middle fossa surgery.
It is a (C)inch: Objective: The middle fossa floor lacks reliable surface landmarks. In cases of superior semicircular canal dehiscence (SSCD), multiple skull base defects may be present, further confounding the location of the labyrinth. Misidentification of the SSCD during surgery may lead...
Head and Neck Diseases
Revision Surgery for Superior Canal Dehiscence Syndrome
Revision Surgery for Superior Canal Dehiscence Syndrome: Objective: To identify factors associated with surgical failure for superior canal dehiscence syndrome (SCDS) and define rates of complications and cure after revision SCDS repair. Study Design: Retrospective patient series. Setting: Tertiary...
Head and Neck Diseases
Discovering Menière's Disease and Its Association With Migraine Headaches
A Historical Recount Objectives: In evaluating the historical context of the first description of Menière's disease, its association with migraine headaches is compelling. We have outlined the events and observations of Prosper Menière, which led him to establish a link between migraine headaches...

Head and Neck Diseases
Correlation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness Handicap
  Otology & Neurotology: September 2016 - Volume 37 - Issue 8 - p 1104–1110 doi: 10.1097/MAO.0000000000001126 Vestibular Disorders Correlation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness Handicap Hunter, Jacob...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Systematic Reviews in Craniofacial Trauma
—Strengths and Weaknesses: Background: Despite substantial advances in the management of craniofacial trauma, numerous clinical questions remain. These are increasingly being answered using systematic reviews (SRs). However, caution is warranted as their validity and role in influencing clinical practice...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Innate Immune Responses to Fungal Allergens
Innate Immune Responses to Fungal Allergens: AbstractPurpose of ReviewIn this review, we describe innate immunity to fungi and the ability of pattern recognition receptors (PRRs) to recognize fungal-associated molecular patterns (FAMPs) and danger-associated molecular patterns (DAMPs).Recent FindingsProtective...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Alpha-Gal Allergy : The syndrome of delayed allergic reactions to the carbohydrate galactose-alpha-1,3-galactose (“alpha-gal”)
Invited Commentary: Alpha-Gal Allergy: Tip of the Iceberg to a Pivotal Immune Response: AbstractThe syndrome of delayed allergic reactions to the carbohydrate galactose-alpha-1,3-galactose (“alpha-gal”) has become increasingly recognized in allergy and immunology clinics regionally throughout the southeastern...
Speech and Hearing Disorders
The Relationship Between the Aerodynamic Parameters of Voice and Perceptual Evaluation in the Iranian Population With or Without Voice Disorders
Publication date: Available online 16 August 2016Source:Journal of VoiceAuthor(s): Mahshid Aghajanzadeh, Akbar Darouie, Payman Dabirmoghaddam, Abolfazl Salehi, Mehdi RahgozarObjectivesAerodynamic evaluations can provide useful information about the interaction between the respiratory and the phonation...
Speech and Hearing Disorders
Lax Vox as a Voice Training Program for Teachers: A Pilot Study
Publication date: Available online 16 August 2016Source:Journal of VoiceAuthor(s): Eva Mailänder, Lea Mühre, Ben BarstiesObjectivesThe objective of this study was to explore the effectiveness of a 3-week training program with the voice therapy “Lax Vox” for teachers.MethodsFour healthy female teachers...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Biomarkers in Occupational Asthma
Biomarkers in Occupational Asthma: AbstractPurpose of ReviewWork-related asthma is a common disorder among adult asthma patients, and in the case of occupational asthma, it is induced by workplace exposures.Recent FindingsOccupational asthma provides an excellent model and benchmark for identifying and...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Climate change, air pollution, and allergic respiratory diseases
: an update.: Purpose of review: The rising trend in prevalence of allergic respiratory disease and bronchial asthma, observed over the last decades, can be explained by changes occurring in the environment, with increasing presence of biologic, such as allergens, and chemical atmospheric trigger factors...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Host genetics affect microbial ecosystems via host immunity.
Host genetics affect microbial ecosystems via host immunity.: Purpose of review: Genetic evolution of multicellular organisms has occurred in response to environmental challenges, including competition for nutrients, climate change, physical and chemical stressors, and pathogens. However, fitness of...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Allergy prevention by breastfeeding: possible mechanisms and evidence from human cohorts.
Allergy prevention by breastfeeding: possible mechanisms and evidence from human cohorts.: Purpose of review: Allergy is a modern disease which does not seem to benefit from breast milk preventive effects. We propose that maternal milk composition has not adapted to the needs of allergy prevention because...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Allergic manifestations of contact lens wearing.
Allergic manifestations of contact lens wearing.: Purpose of review: Contact lens-induced papillary conjunctivitis (CLPC) is a common ocular allergic disease in contact lens wearers. In its more severe form, it can cause giant papillary conjunctivitis, resulting in contact lens intolerance and the need...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Environmental biodiversity protecting from allergy.
The rich and the poor:  Purpose of review: It has been proposed that biodiversity loss leads to reduced interaction between environmental and human microbiotas. This, in turn, may lead to immune dysfunction and impaired tolerance mechanisms in humans. That is, contact with environmental biodiversity...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Ocular allergy.
An update on .: Purpose of Review: The update reviews prevalence, classification, cause, and treatment options for allergic eye disease.Recent Findings: The incidence of allergic eye disease is underreported but may affect almost all patients with allergic rhinitis. Increased rates of oculonasal symptoms...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Epidemiology of severe anaphylaxis
can we use population-based data to understand anaphylaxis?.: Purpose of review: The observed increase in incidence of allergic disease in many regions over the past 3 decades has intensified interest in understanding the epidemiology of severe allergic reactions. We discuss the issues in collecting...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Understanding and treatment of allergic skin diseases.
The 'omics' revolution: redefining the understanding and treatment of allergic skin diseases.: Purpose of review: To evaluate how the genomic, transcriptomic, and proteomic profiles of allergic skin diseases, like atopic dermatitis and allergic contact dermatitis, contribute to their understanding and...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Interleukin-17 and the interleukin-20 family in inflammatory allergic skin diseases.
A systematic review of the role of : Purpose of review: Allergic skin diseases include atopic dermatitis/eczema, contact dermatitis, and drug hypersensitivity. Allergic skin diseases have a high prevalence. Atopic dermatitis is one of the most common inflammatory skin diseases and similar for allergic...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Atopic dermatitis: new evidence on the role of allergic inflammation.
Atopic dermatitis: new evidence on the role of allergic inflammation.: Purpose of review: Atopic dermatitis is a chronic relapsing inflammatory skin disease. In the presence of a complex genetic background, there is increasing evidence for the role of specific allergenic trigger factors in perpetuating...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Asymmetrical Hearing Loss in Cases of Industrial Noise Exposure
A Systematic Review of the Literature: Objective: Asymmetrical hearing thresholds are common in people claiming compensation for noise-induced hearing loss (NIHL). When present and otherwise unexplained, there is some controversy as to whether such asymmetry can be attributed to occupational noise exposure....
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Facial Nerve Disorders and Diseases: Diagnosis and Management: Orlando Guntinas-Lichius and Barry M. Schaitkin; Stuttgart: Thieme, 2015.
Facial Nerve Disorders and Diseases: Diagnosis and Management: Orlando Guntinas-Lichius and Barry M. Schaitkin; Stuttgart: Thieme, 2015.:
OtoRhinoLaryngology - Alexandros G. Sfakianakis
The Impact of Electrode Array Length on Hearing Preservation in Cochlear Implantation
The Impact of Electrode Array Length on Hearing Preservation in Cochlear Implantation:Objective: The aim of the study was to determine the degree of hearing preservation (HP) and its relation to electrode array length after cochlear implantation using different thin flexible electrode arrays (TFEA).Study...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Introduction to the Pharmaceutical Interventions for Hearing Loss Clinical Research Guidance Papers
Introduction to the Pharmaceutical Interventions for Hearing Loss Clinical Research Guidance Papers:
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Electrode Location and Angular Insertion Depth Are Predictors of Audiologic Outcomes in Cochlear Implantation
Otology & Neurotology:September 2016 - Volume 37 - Issue 8 - p 1016–1023doi: 10.1097/MAO.0000000000001125Cochlear ImplantsElectrode Location and Angular Insertion Depth Are Predictors of Audiologic Outcomes in Cochlear ImplantationO’Connell, Brendan P.; Cakir, Ahmet; Hunter, Jacob B.; Francis, David...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Influence of Posterior Fossa Volume on Clinical Outcomes After Vestibular Schwannoma Resection
Influence of Posterior Fossa Volume on Clinical Outcomes After Vestibular Schwannoma Resection: Otology & Neurotology:September 2016 - Volume 37 - Issue 8 - p 1155–1161doi: 10.1097/MAO.0000000000001128Tumors of the Ear and Cranial BaseMacielak, Robert J.; Harris, Michael S.; Kirsch, Claudia F.; Prevedello,...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Stability, Survival, and Tolerability of an Auditory Osseointegrated Implant for Bone Conduction Hearing: Long-Term Follow-Up of a Randomized Controlled Trial
Otology & Neurotology: September 2016 – Volume 37 – Issue 8 – p 1077–1083 doi: 10.1097/MAO.0000000000001111 Prosthetic Devices Stability, Survival, and Tolerability of an Auditory Osseointegrated Implant for Bone Conduction Hearing: Long-Term Follow-Up of a Randomized Controlled Trial den...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Round Window Sealants
The Effect of Round Window Sealants on Delayed Hearing Loss in a Guinea Pig Model of Cochlear Implantation: Aim: To determine whether the type of material used to seal the cochlea after round window cochlear implantation influences delayed hearing loss.Background: Cochlear implants are now prescribed...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Electrode Location and Audiologic Performance After Cochlear Implantation
: A Comparative Study Between Nucleus CI422 and CI512 Electrode Arrays: Objectives: 1) Compare rates of scala tympani (ST) insertion between Nucleus CI422 Slim Straight electrodes and Nucleus CI512 Contour Advance electrodes; 2) examine audiometric performance with both electrode arrays, while controlling...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Role of Facial Nerve Motor-Evoked Potential Ratio in Predicting Facial Nerve Function in Vestibular Schwannoma Surgery Both Immediate and at 1 Year
Role of Facial Nerve Motor-Evoked Potential Ratio in Predicting Facial Nerve Function in Vestibular Schwannoma Surgery Both Immediate and at 1 Year: Objective: To determine whether transcranial electrical stimulation-induced facial motor-evoked potential (FMEP) monitoring of the facial nerve (FN) during...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Modification of Osseointegrated Device Parameters to Improve Speech in Noise and Localization Ability: Clinical Recommendations
Modification of Osseointegrated Device Parameters to Improve Speech in Noise and Localization Ability: Clinical Recommendations: Objective: To determine how best to modify osseointegrated (OI) devices or environmental settings to maximize hearing performance. Study Design: Prospective cohort...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Surgery and Chemoradiotherapy for Temporal Bone Cancer
The Outcomes of  Objective: We aimed to evaluate the prognostic factors and efficacy of treatment modalities for patients with temporal bone cancer, and to determine if definitive chemoradiotherapy (CRT) for advanced-stage disease can provide a substitute for highly invasive surgeries. Study Design:...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Serial Monitoring of Otoacoustic Emissions
 in Clinical Trials: The purpose of this report is to provide guidance on the use of otoacoustic emissions (OAEs) as a clinical trial outcome measure for pharmaceutical interventions developed to prevent acquired hearing loss secondary to cochlear insult. OAEs are a rapid, noninvasive measure that can...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
An Easy and Reliable Method to Locate the Dehiscence During Middle Fossa Superior Canal Dehiscence Surgery: The horizontal distance from the outer cortex of the squama temporalis to the SSCD consistently approximates 1 inch. This easily remembered distance can aid surgeons in locating or confirming the SSCD during middle fossa surgery.
It is a (C)inch: Objective: The middle fossa floor lacks reliable surface landmarks. In cases of superior semicircular canal dehiscence (SSCD), multiple skull base defects may be present, further confounding the location of the labyrinth. Misidentification of the SSCD during surgery may lead...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Revision Surgery for Superior Canal Dehiscence Syndrome
Revision Surgery for Superior Canal Dehiscence Syndrome: Objective: To identify factors associated with surgical failure for superior canal dehiscence syndrome (SCDS) and define rates of complications and cure after revision SCDS repair. Study Design: Retrospective patient series. Setting: Tertiary...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Discovering Menière’s Disease and Its Association With Migraine Headaches
A Historical Recount Objectives: In evaluating the historical context of the first description of Menière’s disease, its association with migraine headaches is compelling. We have outlined the events and observations of Prosper Menière, which led him to establish a link between migraine headaches...

OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Effect of inhibition on tyrosinase and melanogenesis of Agastache rugosa Kuntze by lactic acid bacteria fermentation
Summary BackgroundThis work presents the first report that A. rugosa could have tyrosinase and melanogenesis inhibition and that its activities also be improved by fermentation with Lactobacillus rhamnosus and Lactobacillus paracasei. It was found that the tyrosinase and melanogenesis inhibition was...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Antibiotic prescription and food allergy in young children
To assess the relationship between any systemic antibiotic prescription within the first year of life and the presence of an ICD-9-CM diagnosis code for food allergy (FA). from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/2bmckbH
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Temporal Lobe Gliosarcoma After Gamma Knife Radiosurgery for Vestibular Schwannoma
Temporal Lobe Gliosarcoma After Gamma Knife Radiosurgery for Vestibular Schwannoma: Objective: Secondary tumorigenesis after exposure to ionizing radiation is a well-described phenomenon. The probability of developing a malignancy after stereotactic radiosurgery (SRS) is theoretically less than conventional...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Correlation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness Handicap
  Otology & Neurotology: September 2016 – Volume 37 – Issue 8 – p 1104–1110 doi: 10.1097/MAO.0000000000001126 Vestibular Disorders Correlation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness Handicap Hunter,...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor
Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor: The standard method to determine the output level of acoustic and mechanical stimulation to the inner ear is measurement of vibration response of the stapes in human cadaveric temporal bones (TBs)...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Labyrinthine 3D-FLAIR Abnormalities in Idiopathic Sudden Sensorineural Hearing Loss.
Prognostic Value of  AJNR Am J Neuroradiol. 2016 Aug ; Authors: Lee JI, Yoon RG, Lee JH, Park JW, Yoo MH, Ahn JH, Chung JW, Park HJ Abstract BACKGROUND AND PURPOSE: According to recent research, modern MR imaging can detect the presense of abnormalities on labyrinthine. Our aim was to report...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Cochlear Implantation and Deaf Education
Moving Beyond GDP: Cost Effectiveness of Cochlear Implantation and Deaf Education in Latin America: Hypothesis: Cochlear implantation (CI) and deaf education are cost effective management strategies of childhood profound sensorineural hearing loss in Latin America.Background: CI has been widely established...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Micro CT visualization of silver nanoparticles in the middle and inner ear of rat and transportation pathway after transtympanic injection.
J Nanobiotechnology. Authors: Zou J, Hannula M, Misra S, Feng H, Labrador RH, Aula AS, Hyttinen J, Pyykkö I Abstract BACKGROUND: Silver nanoparticles (Ag NPs) displayed strong activities in anti-bacterial, anti-viral, and anti-fungal studies and were reportedly efficient in treating...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Vestibular Schwannomas: Do Linear and Volumetric Parameters on MRI Correlate With Hearing Loss?
Otology & Neurotology:September 2016 - Volume 37 - Issue 8 - p 1168–1173doi: 10.1097/MAO.0000000000001150Tumors of the Ear and Cranial BaseVestibular Schwannomas: Do Linear and Volumetric Parameters on MRI Correlate With Hearing Loss?Bathla, Girish; Case, Brendan M.; Berbaum, Kevin; Hansen, Marlan...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Ototopical Antibiotics,ciprofloxacin-dexamethasone (CD), ofloxacin (OF), and Cortisporin (CS)
Otology & Neurotology:September 2016 - Volume 37 - Issue 8 - p 1049–1054doi: 10.1097/MAO.0000000000001115Middle Ear and Mastoid DiseaseNational Utilization and Forecasting of Ototopical Antibiotics: Medicaid Data Versus “Dr. Google”Crowson, Matthew G.; Schulz, Kristine; Tucci, Debara L.Supplemental...
health683
Surgery and Chemoradiotherapy for Temporal Bone Cancer
The Outcomes of Objective: We aimed to evaluate the prognostic factors and efficacy of treatment modalities for patients with temporal bone cancer, and to determine if definitive chemoradiotherapy (CRT) for advanced-stage disease can provide a substitute for highly invasive surgeries. Study Design:...
health683
Revision Surgery for Superior Canal Dehiscence Syndrome
Revision Surgery for Superior Canal Dehiscence Syndrome: Objective: To identify factors associated with surgical failure for superior canal dehiscence syndrome (SCDS) and define rates of complications and cure after revision SCDS repair. Study Design: Retrospective patient series. Setting: Tertiary...
health683
An Easy and Reliable Method to Locate the Dehiscence During Middle Fossa Superior Canal Dehiscence Surgery: The horizontal distance from the outer cortex of the squama temporalis to the SSCD consistently approximates 1 inch. This easily remembered distance can aid surgeons in locating or confirming the SSCD during middle fossa surgery.
It is a (C)inch: Objective: The middle fossa floor lacks reliable surface landmarks. In cases of superior semicircular canal dehiscence (SSCD), multiple skull base defects may be present, further confounding the location of the labyrinth. Misidentification of the SSCD during surgery may lead to treatment...
health683
Correlation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness Handicap
Otology & Neurotology:September 2016 – Volume 37 – Issue 8 – p 1104–1110 doi: 10.1097/MAO.0000000000001126 Vestibular Disorders Correlation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness Handicap Hunter, Jacob B.;...
health683
Discovering Menière’s Disease and Its Association With Migraine Headaches
A Historical Recount Objectives: In evaluating the historical context of the first description of Menière’s disease, its association with migraine headaches is compelling. We have outlined the events and observations of Prosper Menière, which led him to establish a link between migraine headaches...
health683
Higher Risk of Ischemic Events in Secondary Prevention for Patients With Persistent Than Those With Paroxysmal Atrial Fibrillation Original Contribution
Background and Purpose— The discrimination between paroxysmal and sustained (persistent or permanent) atrial fibrillation (AF) has not been considered in the approach to secondary stroke prevention. We aimed to assess the differences in clinical outcomes between mostly anticoagulated patients with sustained...
health683
Micro CT visualization of silver nanoparticles in the middle and inner ear of rat and transportation pathway after transtympanic injection.
J Nanobiotechnology. Authors: Zou J, Hannula M, Misra S, Feng H, Labrador RH, Aula AS, Hyttinen J, Pyykkö I Abstract BACKGROUND: Silver nanoparticles (Ag NPs) displayed strong activities in anti-bacterial, anti-viral, and anti-fungal studies and were reportedly efficient in treating otitis media....
health683
Labyrinthine 3D-FLAIR Abnormalities in Idiopathic Sudden Sensorineural Hearing Loss.
Prognostic Value of AJNR Am J Neuroradiol. 2016 Aug ; Authors: Lee JI, Yoon RG, Lee JH, Park JW, Yoo MH, Ahn JH, Chung JW, Park HJ Abstract BACKGROUND AND PURPOSE: According to recent research, modern MR imaging can detect the presense of abnormalities on labyrinthine. Our aim was to report the...
health683
Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor
Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor: The standard method to determine the output level of acoustic and mechanical stimulation to the inner ear is measurement of vibration response of the stapes in human cadaveric temporal bones (TBs)...
health683
Atlantoaxial rotatory fixation (AARF)
Chronic neglected irreducible atlantoaxial rotatory subluxation in adolescence: Pravin Padalkar Journal of Craniovertebral Junction and Spine 2016 7(3):184-188 Atlantoaxial rotatory fixation (AARF) is a rare condition and delayed diagnosis. We report a case of chronic neglected atlantoaxial rotatory...
health683
Increased Frontal Lobe Activation After Aneurysmal Subarachnoid Hemorrhage Original Contribution
Background and Purpose— Neurocognitive deficits are common among survivors of aneurysmal subarachnoid hemorrhage, even among those with good outcomes and no structural lesions. This study aims to probe the neurophysiological underpinnings of cognitive dysfunction among patients with ruptured intracranial...
health683
Proposed clinical internal carotid artery classification system
Proposed clinical internal carotid artery classification system: Saleem I Abdulrauf, Ahmed M Ashour, Eric Marvin, Jeroen Coppens, Brian Kang, Tze Yu Yeh Hsieh, Breno Nery, Juan R Penanes, Aysha K Alsahlawi, Shawn Moore, Hussam Abou Al-Shaar, Joanna Kemp, Kanika Chawla, Nanthiya Sujijantarat, Alaa Najeeb,...
health683
Vascular Tortuosity May Be Associated With Cervical Artery Dissection Original Contribution
Background and Purpose— Dissection is an increasingly recognized cause of ischemic stroke, which occurs spontaneously or after trauma, in relatively young patients. We hypothesized that there might be a predisposing factor weakening the vascular wall and that arterial tortuosity might be higher in patients...
health683
Cervical vertebral maturation (CVM)
Morphological comparison of cervical vertebrae in adult females with different sagittal craniofacial patterns: A cross-sectional study: Ozer Alkan, Cihan Aydogan, Sevil Akkaya Journal of Craniovertebral Junction and Spine 2016 7(3):135-139 Introduction: Cervical vertebral maturation (CVM) methods have...
health683
Neglected dislocation in sub-axial cervical spine
Case series and a suggested treatment protocol: Sudhir Kumar Srivastava, Rishi Anil Aggarwal, Sunil Krishna Bhosale, Pradip Sharad Nemade Journal of Craniovertebral Junction and Spine 2016 7(3):140-145 Context: Approaches suggested for treatment of neglected dislocations in the subaxial cervical spine...
Oncology
Celecoxib for the Prevention of Colorectal Adenomas: Results of a Suspended Randomized Controlled Trial
Background: Cyclooxygenase (COX)-2 inhibitors such as celecoxib were designed to preserve anti-inflammatory activity without inhibiting COX-1. Downregulation of COX-2 inhibits colorectal carcinogenesis. Methods: The Selenium and Celecoxib Trial was a randomized, placebo-controlled trial of once-daily...
Oncology
Selenium Supplementation for Prevention of Colorectal Adenomas and Risk of Associated Type 2 Diabetes
Background: Selenium supplementation may help to prevent colorectal cancer; as precursors of colorectal cancer, colorectal adenomas are a surrogate for colorectal cancer. Selenium supplementation may increase risk of type 2 diabetes (T2D). Methods: The Selenium and Celecoxib (Sel/Cel) Trial was a randomized,...
health683
Pure spinal epidural cavernous hemangiomas (PSECHs)
Pure spinal epidural cavernous hemangioma: A case series of seven cases: Ignatius Ngene Esene, Ahmed M Ashour, Eric Marvin, Mohamed Nosseir, Zeiad Y Fayed, Khaled Seoud, Khaled El Bahy Journal of Craniovertebral Junction and Spine 2016 7(3):176-183 Introduction: Pure spinal epidural cavernous hemangiomas...
Cancer
Corticosteroids for peritumoral edema: time to overcome our addiction?
from #Oncology via alexandrossfakianakis on Inoreader http://ift.tt/2aTvzda via IFTTT
Anatomy Pathology
The 2014 Fred W. Stewart Award: Thomas M. Ulbright, MD
No abstract available from Anatomy Pathology via ola Kala on Inoreader http://ift.tt/2aXbuUI via IFTTT
Cancer
Diverse Cumulative Impact of Chronic Diseases on Physical Health-Related Quality of Life: Implications for a Measure of Multimorbidity
Debate continues on how to measure and weight diseases in multimorbidity. We quantified the association of a broad range of chronic diseases with physical health–related qualify of life and used these weights to develop and validate a multimorbidity weighted index (MWI). Community-dwelling adults in...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Idiopathic Upper Extremity Paresis Following Middle Cranial Fossa Resection of a Vestibular Schwannoma
Parsonage–Turner Syndrome: A Case of   Objective: In this patient report, Parsonage–Turner syndrome (acute brachial neuropathy) developed in our patient 1 day after resection of a vestibular schwannoma by a middle cranial fossa approach. Aiming to increase awareness of this rare disorder among neurotologists,...
ORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Antibiotic prescription and food allergy in young children
To assess the relationship between any systemic antibiotic prescription within the first year of life and the presence of an ICD-9-CM diagnosis code for food allergy (FA). from Allergy via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2bmckbH via IFTTT
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Bilateral Petrous Apex Cephaloceles and Skull Base Attenuation in Setting of Idiopathic Intracranial Hypertension
Bilateral Petrous Apex Cephaloceles and Skull Base Attenuation in Setting of Idiopathic Intracranial Hypertension: 
The Oesophagus
Helicobacter pylori and extragastric diseases
Abstract During the past year, many articles were published on the extragastric diseases related to Helicobacter pylori infection. This supports the theory that some microorganisms may cause diseases even far from the primary site of infection by interfering with different biologic processes. The...
medicinealexandrossfakianakis
Surgery and Chemoradiotherapy for Temporal Bone Cancer
The Outcomes of  Objective: We aimed to evaluate the prognostic factors and efficacy of treatment modalities for patients with temporal bone cancer, and to determine if definitive chemoradiotherapy (CRT) for advanced-stage disease can provide a substitute for highly invasive surgeries. Study Design:...
The Oesophagus
Abstracts
from #Esophageal Cancer via xlomafota13 on Inoreader http://ift.tt/2aXZufz via IFTTT
medicinealexandrossfakianakis
An Easy and Reliable Method to Locate the Dehiscence During Middle Fossa Superior Canal Dehiscence Surgery: The horizontal distance from the outer cortex of the squama temporalis to the SSCD consistently approximates 1 inch. This easily remembered distance can aid surgeons in locating or confirming the SSCD during middle fossa surgery.
It is a (C)inch: Objective: The middle fossa floor lacks reliable surface landmarks. In cases of superior semicircular canal dehiscence (SSCD), multiple skull base defects may be present, further confounding the location of the labyrinth. Misidentification of the SSCD during surgery may lead...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Oxidative Damage and Inflammation Biomarkers: Strategy in Hearing Disorders
Oxidative Damage and Inflammation Biomarkers: Strategy in Hearing Disorders:Importance: Excess free radical-induced oxidative stress and inflammatory processes are increasingly recognized as causative factors in hearing and balance disorders. Antioxidant micronutrients neutralize free radicals and,...
medicinealexandrossfakianakis
Revision Surgery for Superior Canal Dehiscence Syndrome
Revision Surgery for Superior Canal Dehiscence Syndrome: Objective: To identify factors associated with surgical failure for superior canal dehiscence syndrome (SCDS) and define rates of complications and cure after revision SCDS repair. Study Design: Retrospective patient series. Setting: Tertiary...
medicinealexandrossfakianakis
Discovering Menière’s Disease and Its Association With Migraine Headaches
A Historical Recount Objectives: In evaluating the historical context of the first description of Menière’s disease, its association with migraine headaches is compelling. We have outlined the events and observations of Prosper Menière, which led him to establish a link between migraine headaches...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
The Management of Pediatric Unilateral Sensorineural Hearing Loss
The Yield of Multigene Testing in Objective: To explore the role and yield of multigene evaluation in children recently diagnosed with unilateral sensori-neural hearing loss (SNHL).Study Design: Retrospective cohort study.Setting: Tertiary level pediatric institution.Patients: Sixty children diagnosed...
medicinealexandrossfakianakis
Correlation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness Handicap
  Otology & Neurotology: September 2016 – Volume 37 – Issue 8 – p 1104–1110 doi: 10.1097/MAO.0000000000001126 Vestibular Disorders Correlation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness Handicap Hunter,...
medicinealexandrossfakianakis
Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor
Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor: The standard method to determine the output level of acoustic and mechanical stimulation to the inner ear is measurement of vibration response of the stapes in human cadaveric temporal bones (TBs)...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Vestibular Impairment in Dementia
Vestibular Impairment in Dementia: Objective: Recent studies suggest an association between vestibular and cognitive function. The goal of the study was to investigate whether vestibular function was impaired in individuals with mild cognitive impairment (MCI) and Alzheimer's disease (AD) compared with...
medicinealexandrossfakianakis
Labyrinthine 3D-FLAIR Abnormalities in Idiopathic Sudden Sensorineural Hearing Loss.
Prognostic Value of  AJNR Am J Neuroradiol. 2016 Aug ; Authors: Lee JI, Yoon RG, Lee JH, Park JW, Yoo MH, Ahn JH, Chung JW, Park HJ Abstract BACKGROUND AND PURPOSE: According to recent research, modern MR imaging can detect the presense of abnormalities on labyrinthine. Our aim was to report...
medicinealexandrossfakianakis
Micro CT visualization of silver nanoparticles in the middle and inner ear of rat and transportation pathway after transtympanic injection.
J Nanobiotechnology. Authors: Zou J, Hannula M, Misra S, Feng H, Labrador RH, Aula AS, Hyttinen J, Pyykkö I Abstract BACKGROUND: Silver nanoparticles (Ag NPs) displayed strong activities in anti-bacterial, anti-viral, and anti-fungal studies and were reportedly efficient in treating...
OtoRhinoLaryngology - Head and Neck Surgery
Antibiotic prescription and food allergy in young children
To assess the relationship between any systemic antibiotic prescription within the first year of life and the presence of an ICD-9-CM diagnosis code for food allergy (FA).http://ift.tt/2bmckbH
medicinealexandrossfakianakis
Atlantoaxial rotatory fixation (AARF)
Chronic neglected irreducible atlantoaxial rotatory subluxation in adolescence: Pravin Padalkar Journal of Craniovertebral Junction and Spine 2016 7(3):184-188 Atlantoaxial rotatory fixation (AARF) is a rare condition and delayed diagnosis. We report a case of chronic neglected atlantoaxial rotatory...

OtoRhinoLaryngology - Alexandros G. Sfakianakis
Transcanal Endoscopic Ear Surgery for the Management of Congenital Ossicular Fixation
Transcanal Endoscopic Ear Surgery for the Management of Congenital Ossicular Fixation: Objectives: 1) To describe the technique for transcanal endoscopic management of congenital ossicular chain fixation. 2) To highlight the utility and outcomes of the endoscopic approach for management of congenital...
medicinealexandrossfakianakis
Higher Risk of Ischemic Events in Secondary Prevention for Patients With Persistent Than Those With Paroxysmal Atrial Fibrillation [Original Contribution]
Background and Purpose— The discrimination between paroxysmal and sustained (persistent or permanent) atrial fibrillation (AF) has not been considered in the approach to secondary stroke prevention. We aimed to assess the differences in clinical outcomes between mostly anticoagulated patients with...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Risk Assessment and Prevention of Corneal Complications After Lateral Skull Base Surgery
Risk Assessment and Prevention of Corneal Complications After Lateral Skull Base Surgery: Objective: To analyze the rate of corneal complications after lateral skull base surgery, and the relative risk of each potential contributing factor.Study Design: Retrospective cohort study.Setting: Tertiary care...
medicinealexandrossfakianakis
Increased Frontal Lobe Activation After Aneurysmal Subarachnoid Hemorrhage [Original Contribution]
Background and Purpose— Neurocognitive deficits are common among survivors of aneurysmal subarachnoid hemorrhage, even among those with good outcomes and no structural lesions. This study aims to probe the neurophysiological underpinnings of cognitive dysfunction among patients with ruptured intracranial...
medicinealexandrossfakianakis
Vascular Tortuosity May Be Associated With Cervical Artery Dissection [Original Contribution]
Background and Purpose— Dissection is an increasingly recognized cause of ischemic stroke, which occurs spontaneously or after trauma, in relatively young patients. We hypothesized that there might be a predisposing factor weakening the vascular wall and that arterial tortuosity might be higher in...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Stability, Survival, and Tolerability of an Auditory Osseointegrated Implant for Bone Conduction Hearing: Long-Term Follow-Up of a Randomized Controlled Trial
Otology & Neurotology:September 2016 - Volume 37 - Issue 8 - p 1077–1083doi: 10.1097/MAO.0000000000001111Prosthetic DevicesStability, Survival, and Tolerability of an Auditory Osseointegrated Implant for Bone Conduction Hearing: Long-Term Follow-Up of a Randomized Controlled Trialden Besten, Christine...
medicinealexandrossfakianakis
Cervical vertebral maturation (CVM)
Morphological comparison of cervical vertebrae in adult females with different sagittal craniofacial patterns: A cross-sectional study: Ozer Alkan, Cihan Aydogan, Sevil Akkaya Journal of Craniovertebral Junction and Spine 2016 7(3):135-139 Introduction: Cervical vertebral maturation (CVM) methods have...
medicinealexandrossfakianakis
Proposed clinical internal carotid artery classification system
Proposed clinical internal carotid artery classification system: Saleem I Abdulrauf, Ahmed M Ashour, Eric Marvin, Jeroen Coppens, Brian Kang, Tze Yu Yeh Hsieh, Breno Nery, Juan R Penanes, Aysha K Alsahlawi, Shawn Moore, Hussam Abou Al-Shaar, Joanna Kemp, Kanika Chawla, Nanthiya Sujijantarat, Alaa Najeeb,...
medicinealexandrossfakianakis
Neglected dislocation in sub-axial cervical spine
Case series and a suggested treatment protocol: Sudhir Kumar Srivastava, Rishi Anil Aggarwal, Sunil Krishna Bhosale, Pradip Sharad Nemade Journal of Craniovertebral Junction and Spine 2016 7(3):140-145 Context: Approaches suggested for treatment of neglected dislocations in the subaxial cervical spine...
medicinealexandrossfakianakis
Pure spinal epidural cavernous hemangiomas (PSECHs)
Pure spinal epidural cavernous hemangioma: A case series of seven cases: Ignatius Ngene Esene, Ahmed M Ashour, Eric Marvin, Mohamed Nosseir, Zeiad Y Fayed, Khaled Seoud, Khaled El Bahy Journal of Craniovertebral Junction and Spine 2016 7(3):176-183 Introduction: Pure spinal epidural cavernous hemangiomas...
medicinealexandrossfakianakis
The anterior hypothalamus in cluster headache
Objective To evaluate the presence, localization, and specificity of structural hypothalamic and whole brain changes in cluster headache and chronic paroxysmal hemicrania (CPH). Methods We compared T1-weighted magnetic resonance images of subjects with cluster headache (episodic n = 24; chronic...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Role of Facial Nerve Motor-Evoked Potential Ratio in Predicting Facial Nerve Function in Vestibular Schwannoma Surgery Both Immediate and at 1 Year
Role of Facial Nerve Motor-Evoked Potential Ratio in Predicting Facial Nerve Function in Vestibular Schwannoma Surgery Both Immediate and at 1 Year:Objective: To determine whether transcranial electrical stimulation-induced facial motor-evoked potential (FMEP) monitoring of the facial nerve (FN) during...
medicinealexandrossfakianakis
The Relationship Between the Aerodynamic Parameters of Voice and Perceptual Evaluation in the Iranian Population With or Without Voice Disorders
Publication date: Available online 16 August 2016Source:Journal of Voice Author(s): Mahshid Aghajanzadeh, Akbar Darouie, Payman Dabirmoghaddam, Abolfazl Salehi, Mehdi Rahgozar ObjectivesAerodynamic evaluations can provide useful information about the interaction between the respiratory and the phonation...
medicinealexandrossfakianakis
Lax Vox as a Voice Training Program for Teachers: A Pilot Study
Publication date: Available online 16 August 2016Source:Journal of Voice Author(s): Eva Mailänder, Lea Mühre, Ben Barsties ObjectivesThe objective of this study was to explore the effectiveness of a 3-week training program with the voice therapy “Lax Vox” for teachers.MethodsFour healthy female teachers...
medicinealexandrossfakianakis
Lax Vox as a Voice Training Program for Teachers: A Pilot Study
Publication date: Available online 16 August 2016Source:Journal of Voice Author(s): Eva Mailänder, Lea Mühre, Ben Barsties ObjectivesThe objective of this study was to explore the effectiveness of a 3-week training program with the voice therapy “Lax Vox” for teachers.MethodsFour healthy female...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Modification of Osseointegrated Device Parameters to Improve Speech in Noise and Localization Ability: Clinical Recommendations
Modification of Osseointegrated Device Parameters to Improve Speech in Noise and Localization Ability: Clinical Recommendations: Objective: To determine how best to modify osseointegrated (OI) devices or environmental settings to maximize hearing performance.Study Design: Prospective cohort study.Setting:...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Surgery and Chemoradiotherapy for Temporal Bone Cancer
The Outcomes of Objective: We aimed to evaluate the prognostic factors and efficacy of treatment modalities for patients with temporal bone cancer, and to determine if definitive chemoradiotherapy (CRT) for advanced-stage disease can provide a substitute for highly invasive surgeries.Study Design: Retrospective...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
An Easy and Reliable Method to Locate the Dehiscence During Middle Fossa Superior Canal Dehiscence Surgery: The horizontal distance from the outer cortex of the squama temporalis to the SSCD consistently approximates 1 inch. This easily remembered distance can aid surgeons in locating or confirming the SSCD during middle fossa surgery.
It is a (C)inch: Objective: The middle fossa floor lacks reliable surface landmarks. In cases of superior semicircular canal dehiscence (SSCD), multiple skull base defects may be present, further confounding the location of the labyrinth. Misidentification of the SSCD during surgery may lead to treatment...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Revision Surgery for Superior Canal Dehiscence Syndrome
Revision Surgery for Superior Canal Dehiscence Syndrome:Objective: To identify factors associated with surgical failure for superior canal dehiscence syndrome (SCDS) and define rates of complications and cure after revision SCDS repair.Study Design: Retrospective patient series.Setting: Tertiary care...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Discovering Menière's Disease and Its Association With Migraine Headaches
A Historical RecountObjectives: In evaluating the historical context of the first description of Menière's disease, its association with migraine headaches is compelling. We have outlined the events and observations of Prosper Menière, which led him to establish a link between migraine headaches and...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Correlation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness Handicap
 Otology & Neurotology:September 2016 - Volume 37 - Issue 8 - p 1104–1110doi: 10.1097/MAO.0000000000001126Vestibular DisordersCorrelation of Superior Canal Dehiscence Surface Area With Vestibular Evoked Myogenic Potentials, Audiometric Thresholds, and Dizziness HandicapHunter, Jacob B.; O’Connell,...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor
Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor: The standard method to determine the output level of acoustic and mechanical stimulation to the inner ear is measurement of vibration response of the stapes in human cadaveric temporal bones (TBs)...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Labyrinthine 3D-FLAIR Abnormalities in Idiopathic Sudden Sensorineural Hearing Loss.
Prognostic Value of AJNR Am J Neuroradiol. 2016 Aug ;Authors: Lee JI, Yoon RG, Lee JH, Park JW, Yoo MH, Ahn JH, Chung JW, Park HJAbstract BACKGROUND AND PURPOSE: According to recent research, modern MR imaging can detect the presense of abnormalities on labyrinthine. Our aim was to report the...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Micro CT visualization of silver nanoparticles in the middle and inner ear of rat and transportation pathway after transtympanic injection.
J Nanobiotechnology.Authors: Zou J, Hannula M, Misra S, Feng H, Labrador RH, Aula AS, Hyttinen J, Pyykkö IAbstract BACKGROUND: Silver nanoparticles (Ag NPs) displayed strong activities in anti-bacterial, anti-viral, and anti-fungal studies and were reportedly efficient in treating otitis media....
Swallowing and Swallowing Disorders (Dysphagia)
The Relationship Between the Aerodynamic Parameters of Voice and Perceptual Evaluation in the Iranian Population With or Without Voice Disorders
Publication date: Available online 16 August 2016Source:Journal of VoiceAuthor(s): Mahshid Aghajanzadeh, Akbar Darouie, Payman Dabirmoghaddam, Abolfazl Salehi, Mehdi RahgozarObjectivesAerodynamic evaluations can provide useful information about the interaction between the respiratory and the phonation...
Swallowing and Swallowing Disorders (Dysphagia)
Lax Vox as a Voice Training Program for Teachers: A Pilot Study
Publication date: Available online 16 August 2016Source:Journal of VoiceAuthor(s): Eva Mailänder, Lea Mühre, Ben BarstiesObjectivesThe objective of this study was to explore the effectiveness of a 3-week training program with the voice therapy “Lax Vox” for teachers.MethodsFour healthy female teachers...
Swallowing and Swallowing Disorders (Dysphagia)
Diagnostic Accuracy of the Modified Evan’s Blue Dye Test in Detecting Aspiration in Patients with Tracheostomy: A Systematic Review of the Evidence
AbstractOropharyngeal aspiration (OPA) is a common occurrence in patients with tracheostomy. The modified Evan’s blue dye test (MEBDT) is an easily administered bedside procedure for the assessment of tracheostomised patients. However, studies evaluating the diagnostic accuracy of the MEBDT reach conflicting...
Medicine….iliofanis
Impact of including or excluding both-armed zero-event studies on using standard meta-analysis methods for rare event outcome: a simulation study
Objectives There is no consensus on whether studies with no observed events in the treatment and control arms, the so-called both-armed zero-event studies, should be included in a meta-analysis of randomised controlled trials (RCTs). Current analytic approaches handled them differently depending on...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Motion analysis in the field of dentistry: a kinematic comparison of dentists and orthodontists
Objectives To conduct a kinematic comparison of occupational posture in orthodontists and dentists in their workplace. Design Observational study. Setting Dentist surgeries and departments of orthodontics at university medical centres in Germany. Participants A representative sample of 21 (10...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Associations of neonatal high birth weight with maternal pre-pregnancy body mass index and gestational weight gain: a case-control study in women from Chongqing, China
Objectives To examine the associations of maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) with neonatal high birth weight (HBW) in a sample of Chinese women living in southwest China. Methods A hospital-based case–control study was conducted in Chongqing, China. A total...
Medicine….iliofanis
Trend study on the association between hospital admissions and the health of Dutch older adults (1995-2009)
Objectives An increase in hospital admission rates in older people may reflect improved access to healthcare, but also declining health trends in the older population. Owing to a lack of individual-level data, the latter possibility has received little attention. The current study examines associations...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Improving the performance of community health workers in humanitarian emergencies: a realist evaluation protocol for the PIECES programme
Introduction Understanding what enhances the motivation and performance of community health workers (CHWs) in humanitarian emergencies represents a key research gap within the field of human resources for health. This paper presents the research protocol for the Performance ImprovEment of CHWs in Emergency...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Occupational Therapy in HomEcare Re-ablement Services (OTHERS): results of a feasibility randomised controlled trial
Objectives The objective of this study was to test the feasibility of conducting a randomised controlled trial (RCT) of an intervention targeted at activities of daily living (ADL), delivered by an occupational therapist, in homecare reablement. Design Feasibility parallel group RCT. Setting Single-site...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Interprofessional education in the care of people diagnosed with dementia and their carers: a systematic review
Objectives This systematic review is linked to the multifaceted social, economic and personal challenges of dementia and the international recognition of the value of interprofessional education (IPE) and its influence on health and social care outcomes. This review therefore aimed to identify, describe...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Impact of including or excluding both-armed zero-event studies on using standard meta-analysis methods for rare event outcome: a simulation study
Objectives There is no consensus on whether studies with no observed events in the treatment and control arms, the so-called both-armed zero-event studies, should be included in a meta-analysis of randomised controlled trials (RCTs). Current analytic approaches handled them differently depending on...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Trend study on the association between hospital admissions and the health of Dutch older adults (1995-2009)
Objectives An increase in hospital admission rates in older people may reflect improved access to healthcare, but also declining health trends in the older population. Owing to a lack of individual-level data, the latter possibility has received little attention. The current study examines associations...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Atlantoaxial rotatory fixation (AARF)
Chronic neglected irreducible atlantoaxial rotatory subluxation in adolescence: Pravin PadalkarJournal of Craniovertebral Junction and Spine 2016 7(3):184-188Atlantoaxial rotatory fixation (AARF) is a rare condition and delayed diagnosis. We report a case of chronic neglected atlantoaxial rotatory subluxation...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Higher Risk of Ischemic Events in Secondary Prevention for Patients With Persistent Than Those With Paroxysmal Atrial Fibrillation [Original Contribution]
Background and Purpose— The discrimination between paroxysmal and sustained (persistent or permanent) atrial fibrillation (AF) has not been considered in the approach to secondary stroke prevention. We aimed to assess the differences in clinical outcomes between mostly anticoagulated patients with...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Increased Frontal Lobe Activation After Aneurysmal Subarachnoid Hemorrhage [Original Contribution]
Background and Purpose— Neurocognitive deficits are common among survivors of aneurysmal subarachnoid hemorrhage, even among those with good outcomes and no structural lesions. This study aims to probe the neurophysiological underpinnings of cognitive dysfunction among patients with ruptured intracranial...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Vascular Tortuosity May Be Associated With Cervical Artery Dissection [Original Contribution]
Background and Purpose— Dissection is an increasingly recognized cause of ischemic stroke, which occurs spontaneously or after trauma, in relatively young patients. We hypothesized that there might be a predisposing factor weakening the vascular wall and that arterial tortuosity might be higher in...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Cervical vertebral maturation (CVM)
Morphological comparison of cervical vertebrae in adult females with different sagittal craniofacial patterns: A cross-sectional study: Ozer Alkan, Cihan Aydogan, Sevil AkkayaJournal of Craniovertebral Junction and Spine 2016 7(3):135-139Introduction: Cervical vertebral maturation (CVM) methods have...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Proposed clinical internal carotid artery classification system
Proposed clinical internal carotid artery classification system: Saleem I Abdulrauf, Ahmed M Ashour, Eric Marvin, Jeroen Coppens, Brian Kang, Tze Yu Yeh Hsieh, Breno Nery, Juan R Penanes, Aysha K Alsahlawi, Shawn Moore, Hussam Abou Al-Shaar, Joanna Kemp, Kanika Chawla, Nanthiya Sujijantarat, Alaa Najeeb,...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Neglected dislocation in sub-axial cervical spine
Case series and a suggested treatment protocol: Sudhir Kumar Srivastava, Rishi Anil Aggarwal, Sunil Krishna Bhosale, Pradip Sharad NemadeJournal of Craniovertebral Junction and Spine 2016 7(3):140-145Context: Approaches suggested for treatment of neglected dislocations in the subaxial cervical spine...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Pure spinal epidural cavernous hemangiomas (PSECHs)
Pure spinal epidural cavernous hemangioma: A case series of seven cases: Ignatius Ngene Esene, Ahmed M Ashour, Eric Marvin, Mohamed Nosseir, Zeiad Y Fayed, Khaled Seoud, Khaled El BahyJournal of Craniovertebral Junction and Spine 2016 7(3):176-183Introduction: Pure spinal epidural cavernous hemangiomas...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Picture naming in typically developing and language-impaired children: the role of sustained attention
Abstract Background Children with specific language impairment (SLI) have problems not only with language performance but also with sustained attention, which is the ability to maintain alertness over an extended period of time. Although there is consensus that this ability is impaired with respect...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Neighbourhoods for Active Kids: study protocol for a cross-sectional examination of neighbourhood features and children’s physical activity, active travel, independent mobility and body size
Introduction New Zealand children’s physical activity, including independent mobility and active travel, has declined markedly over recent decades. The Neighbourhoods for Active Kids (NfAK) study examines how neighbourhood built environments are associated with the independent mobility, active travel,...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Prevalence and determinants of depressive and anxiety symptoms in adults with type 2 diabetes in China: a cross-sectional study
Objectives To evaluate the prevalence and determinants of anxiety and depression and to assess their impact on glycaemic control in participants with type 2 diabetes mellitus. Design A cross-sectional study. Setting Community-based investigation in Xuzhou, China. Participants 893 Chinese men and...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Innovative approach for increasing physical activity among breast cancer survivors: protocol for Project MOVE, a quasi-experimental study
Introduction Physical activity is a cost-effective and non-pharmaceutical strategy that can help mitigate the physical and psychological health challenges associated with breast cancer survivorship. However, up to 70% of women breast cancer survivors are not meeting minimum recommended physical activity...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Compliant flooring to prevent fall-related injuries: a scoping review protocol
Introduction Fall-related injuries can have serious consequences for older adults, including increased risk of dependence in daily activities and mortality. Compliant flooring is a passive intervention that may reduce the incidence and severity of fall-related injuries in healthcare settings, including...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Metformin for endometrial hyperplasia: a Cochrane protocol
Introduction Endometrial hyperplasia is a precancerous lesion of the endometrium, commonly presenting with uterine bleeding. If managed expectantly, it frequently progresses to endometrial carcinoma, rates of which are increasing dramatically worldwide. However, the established treatment for endometrial...        

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