08:20
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Changes in hydration of the stratum corneum are the most suitable indicator to evaluate the irritation of surfactants on the skin: Background/PurposeIrritancy levels of surfactants on human skin have not been clarified completely. The relationships between skin damage and changes of skin properties caused...
08:20
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Current perspective on actinic keratosis: a review: SummaryActinic keratoses (AKs) are common, with prevalence in the U.S.A. estimated at almost 40 million in 2004 and annual costs of > $1 billion (U.S.D.). However, there is no universally accepted definition of AK and thus it is difficult to identify...
08:19
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Does it differ from the adult counterpart?: SummaryBackgroundPrimary cutaneous marginal zone B-cell lymphoma (PCMZL) has rarely been reported in patients younger than 20 years.ObjectivesTo report our experience with PCMZL in the paediatric/adolescent age group.MethodsMedical records of patients diagnosed...
08:18
OtoRhinoLaryngology - Alexandros G. Sfakianakis
E7 TCR T Cells With or Without PD-1 Blockade for Human Papillomavirus-Associated Cancers: Conditions: Cervical Cancer; Vaginal Cancer; Anal Cancer; Penile Cancer; Oropharyngeal CancerInterventions: Biological: E7 TCR cells; Drug: pembrolizumab; Drug: aldesleukin; Drug: fludarabine;...
08:18
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Study Evaluating a Stereotactic Boost/Treatment for Recurrent or Metastatic Cancer of the Head and Neck: Conditions: Recurrent Head and Neck Carcinoma; Head and Neck Cancer Metastatic; Head or Neck CancerInterventions: Radiation: Intensity Modulated Radiation Therapy (IMRT); Drug: Cisplatin;...
08:12
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Circular RNA expression in cutaneous squamous cell carcinomavia ScienceDirect Publication: Journal of Dermatological SciencePublication date: September 2016Source:Journal of Dermatological Science, Volume 83, Issue 3Author(s): Michael Sand, Falk G. Bechara, Thilo Gambichler, Daniel Sand, Michael Bromba,...
08:10
OtoRhinoLaryngology - Alexandros G. Sfakianakis
in German, Chinese and Japanese women manifests differently in all three groups depending on ethnic background, age and anatomical sitevia ScienceDirect Publication: Journal of Dermatological SciencePublication date: September 2016Source:Journal of Dermatological Science, Volume 83, Issue 3Author(s):...
08:09
OtoRhinoLaryngology - Alexandros G. Sfakianakis
; a case-control studyvia ScienceDirect Publication: Journal of Dermatological SciencePublication date: September 2016Source:Journal of Dermatological Science, Volume 83, Issue 3Author(s): Rania Abdel Hay, Laila Rashed, Rehab Hegazy, Weam Rashwan, Nesrin Samir, Faisal Nour-Edin... Association of interleukin (IL)18 and IL10 gene polymorphisms with oral lichen planus risk;...
08:07
OtoRhinoLaryngology - Alexandros G. Sfakianakis
p62 modulates the intrinsic signaling of UVB-induced apoptosisvia ScienceDirect Publication: Journal of Dermatological SciencePublication date: September 2016Source:Journal of Dermatological Science, Volume 83, Issue 3Author(s): Sachiko Ito, Shintaro Kimura, Eiji Warabi, Yasuhiro Kawachi, Masanobu Yamatoji,...
08:05
OtoRhinoLaryngology - Alexandros G. Sfakianakis
: An anti-inflammatory treatment modality for initial hidradenitis suppurativavia ScienceDirect Publication: Journal of Dermatological SciencePublication date: Available online 10 August 2016Source:Journal of Dermatological ScienceAuthor(s): Schapoor Hessam, Michael Sand, Nina Mareike Meier, Thilo Gambichler,...
08:04
OtoRhinoLaryngology - Alexandros G. Sfakianakis
: A randomized, placebo-controlled, double-blind studyupdated on Wed Aug 17, 2016 14:47 via ScienceDirect Publication: Journal of Dermatological ScienceSource:Journal of Dermatological ScienceAuthor(s): Cecilie Scheuer, Hans-Christian Pommergaard, Jacob Rosenberg, Ismail GögenurBackgroundUltraviolet...
08:03
OtoRhinoLaryngology - Alexandros G. Sfakianakis
in patients with atopic dermatitisvia ScienceDirect Publication: Journal of Dermatological ScienceSource:Journal of Dermatological ScienceAuthor(s): Y. Zhang, Y. Luo, W. Li, J. Liu, M. Chen, H. Gu, B. Wang, X. YaoBackgroundAtopic dermatitis (AD) is a common inflammatory skin disease, concomitant with...
08:02
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Interdental papilla loss: treatment by hyaluronic acid gel injection: a case series: AbstractObjectivesThe purpose of this prospective clinical trial was to examine the clinical and patient outcomes following esthetic reconstruction of interdental papilla loss in anterior teeth, using an injectable,...
08:01
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Prevalence of otologic signs and symptoms in adult patients with temporomandibular disorders: a systematic review and meta-analysis: AbstractObjectiveThis study aims to estimate the prevalence of otologic signs and symptoms in adult patients with temporomandibular disorders (TMD).Material and methodsSearch...
08:00
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Serum thyroid function, mortality and disability in advanced old age: The Newcastle 85+ study: The Journal of Clinical Endocrinology &Metabolism, Early Release. Simon HS Pearce1, Salman Razvi1, Mohammad E Yadegarfar2, Carmen Martin-Ruiz2, Andrew Kingston2, Joanna Collerton2, Theo J Visser3, Tom B...
07:58
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Characterization of Tumor Size Changes Over Time From the Phase 3 Study of Lenvatinib in Thyroid Cancer: The Journal of Clinical Endocrinology &Metabolism, Early Release. Bruce Robinson1, Martin Schlumberger2, Lori J. Wirth3, Corina E. Dutcus4, James Song5, Matthew H. Taylor6, Sung-Bae Kim7, Monika...
07:57
OtoRhinoLaryngology - Alexandros G. Sfakianakis
IRAK1, a Target of miR-146b, Reduces Cell Aggressiveness of Human Papillary Thyroid Carcinoma: The Journal of Clinical Endocrinology &Metabolism, Early Release. Chen-Kai Chou1,2, Shun-Yu Chi3, Cai-Hua Huang1, Fong-Fu Chou3, Chao-Cheng Huang4, Rue-Tsuan Liu1,†, and Hong-Yo Kang2,5,†Address all correspondence...
07:57
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Risk Factors of 131I-Induced Salivary Gland Damage in Thyroid Cancer Patients: The Journal of Clinical Endocrinology &Metabolism, Early Release. Brynn Hollingsworth1, Leigha Senter2, Xiaoli Zhang3,5, Guy N. Brock3,5, Wael Jarjour4, Rebecca Nagy2,#, Pamela Brock2, Kevin R. Coombes5, Richard Kloos6,*,...
07:56
OtoRhinoLaryngology - Alexandros G. Sfakianakis
68Ga-DOTATATE for Tumor Localization in Tumor-induced Osteomalacia: The Journal of Clinical Endocrinology &Metabolism, Early Release. Diala El-Maouche1,2, Samira M. Sadowski3,4, Georgios Z. Papadakis5, Lori Guthrie2, Candice Cottle-Delisle4, Roxanne Merkel4, Corina Millo5, Clara C. Chen6, Electron...
07:55
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Comprehensive screening of eight known causative genes in congenital hypothyroidism with gland-in-situ: The Journal of Clinical Endocrinology &Metabolism, Early Release. AK Nicholas1,*, EG Serra2,*, H Cangul3, S Alyaarubi4, I Ullah4, E Schoenmakers1, A Deeb5, AM Habeb6, M AlMaghamsi7, C Peters8,...
07:54
OtoRhinoLaryngology - Alexandros G. Sfakianakis
PTH(1–34) for the primary prevention of post-thyroidectomy hypocalcemia: the THYPOS trial: The Journal of Clinical Endocrinology &Metabolism, Early Release. A. Palermo1,*, G. Mangiameli2,*, G. Tabacco1, F. Longo2, C. Pedone3, S.I. Briganti1, D. Maggi1, F. Vescini4, A. Naciu1, A. Lauria Pantano1,...
07:53
OtoRhinoLaryngology - Alexandros G. Sfakianakis
The Vitamin D Receptor Regulates Tissue Resident Macrophage Response to Injury: Endocrinology, Early Release. Lige Songa, Garyfallia Papaioannoua, Hengguang Zhaoa, Hilary F. Luderera, Christine Millerc, Claudia Dall'Ossoc, Rosalynn M. Nazarianb, Amy J. Wagersc, and Marie B. DemayaAddress all correspondence...
07:52
OtoRhinoLaryngology - Alexandros G. Sfakianakis
The circadian timing system and environmental circadian disruption: From follicles to fertility: Endocrinology, Early Release. Aritro Sen and Michael T. SellixAddress all correspondence and requests for reprints to: Michael T. Sellix Ph.D.,Department of Medicine, Division of Endocrinology and Metabolism,...
07:51
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Estrogen and Microbiota Crosstalk: Should We Pay Attention?via ScienceDirect Publication: Trends in Endocrinology & MetabolismPublication date: Available online 20 August 2016Source:Trends in Endocrinology & MetabolismAuthor(s): Karen L. Chen, Zeynep Madak-ErdoganRecent advances have suggested...
07:50
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Olaparib does not cause clinically relevant QT/QT c interval prolongation in patients with advanced solid tumours: results from two phase I studies: AbstractBackgroundSome therapeutic agents in oncology can be causally associated with specific cardiovascular events including QT/QTc interval prolongation....
07:50
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Silencing of fused toes homolog enhances cisplatin sensitivity in cervical cancer cells by inhibiting epidermal growth factor receptor-mediated repair of DNA damage: AbstractPurposeOverexpression of epidermal growth factor receptor (EGFR) is related to chemo-/radioresistance and poor prognosis in many...
07:49
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Generalized spastic dystonic cerebral palsy with regression of motor milestones due to congenital atlantoaxial dislocation: A diagnostic dilemma and rare association: Pavan Kumar Pelluru, Aniruddh Kumar PurohitIndian Journal of Cerebral Palsy 2016 2(1):48-50In spastic cerebral palsy cervical dystonia...
07:49
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Sanjad-Sakati syndrome: Beyond the Middle-East: Chetana Sen, Sandip Pal, Prasenjit Sengupta, Asutosh Pal, Jacky Ganguly, Chiranjib Das, Debasish BasuIndian Journal of Cerebral Palsy 2016 2(1):54-57Sanjad-Sakati syndrome (OMIM 241410), also known as hypoparathyroidism-retardation-dysmorphism (HRD) syndrome,...
07:48
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Improvization of conventional cytology by centrifuged liquid-based cytology in oral exfoliative cytology specimen: Shwetha Nambiar, Veda Hegde, Nikhil Yadav, Kaveri HallikeriJournal of Cytology 2016 33(3):115-119Background: Exfoliative cytology is the microscopic examination of shed or desquamated cells...
07:48
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Rare cytological findings: Maral Mokhtari, Perikala Vijayananda Kumar, Kamran HayatiJournal of Cytology 2016 33(3):120-124Background: Cystic papillary thyroid carcinoma (CPTC) is a variant of papillary carcinoma that has many mimickers in cytological grounds. Aim: To study the cytomorphologic features...
07:48
OtoRhinoLaryngology - Alexandros G. Sfakianakis
A rare cytological diagnosis: Gopal Krishna Sawke, Tina Rai, Nilima SawkeJournal of Cytology 2016 33(3):166-168Calcinosis cutis is an uncommon condition characterized by the deposition of calcium salts in the subcutaneous tissues of the body. Calcifications can also occur in a variety of other clinical...
07:47
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Evaluation of cytomorphometric changes in tobacco users and diagnosed oral squamous cell carcinoma individuals: Urmila Udayashankar, Vijay Srinivas Guduru, Anuradha Ananthaneni, Sabitha Devi Ramisetty, Puneeth Horatti Kuberappa, Srilekha NamalaJournal of Cytology 2016 33(3):125-129Aims: To determine...
07:47
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Cytological grading: An alternative to histological grading in oral squamous cell carcinoma: Srilekha Namala, Vijay Srinivas Guduru, Anuradha Ananthaneni, Sabitha Devi, Puneeth Horrati Kuberappa, Urmila UdayashankarJournal of Cytology 2016 33(3):130-134Background: Micronuclei (MN) in oral exfoliative...
07:47
OtoRhinoLaryngology - Alexandros G. Sfakianakis
A case report: Ajithakumari Kumaran, Sathi PuthenparambathJournal of Cytology 2016 33(3):172-174A 10-year-old boy presented with a swelling of the left mid upper arm of 1 month duration. Fine-needle aspiration (FNA) diagnosis of pseudosarcomatous lesion, suggestive of nodular fasciitis, was made and...
07:47
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Cytodiagnosis of disseminated histoplasmosis in an immunocompetent individual with molluscum contagiosum-like skin lesions and lymphadenopathy: Prajwala Gupta, Minakshi BhardwajJournal of Cytology 2016 33(3):163-165Disseminated histoplasmosis is caused by the dimorphic fungus Histoplasma capsulatum (H....
07:46
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Cytomorphologic spectrum of lymphocytic thyroiditis and correlation between cytological grading and biochemical parameters: KR Anila, Nileena Nayak, K JayasreeJournal of Cytology 2016 33(3):145-149Introduction: Chronic lymphocytic thyroiditis [Hashimoto thyroiditis (HT)] is a common thyroid lesion diagnosed...
07:46
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Evaluation of empiric antibiotic de-escalation in febrile neutropenia: IntroductionUp until 2010, the recommended duration of empiric broad-spectrum antibiotics for febrile neutropenia was until absolute neutrophil count (ANC) recovery. An updated guideline on the use of antimicrobial agents in neutropenic...
07:45
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Comorbidities among patients with cancer who do and do not develop febrile neutropenia during the first chemotherapy cycle: Patients receiving myelosuppressive chemotherapy with certain comorbidities are at increased risk of febrile neutropenia. A comprehensive evaluation of febrile neutropenia-related...
07:45
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Comparative effectiveness of granulocyte colony-stimulating factors to prevent febrile neutropenia and related complications in cancer patients in clinical practice: A systematic review: IntroductionFebrile neutropenia (FN) is a serious side-effect of myelosuppressive chemotherapy. Several clinical trials...
07:44
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Fatal pulmonary toxicity due to carfilzomib (Kyprolis™): IntroductionCarfilzomib (Kyprolis™) is a second-generation proteasome inhibitor for the treatment of relapsing multiple myeloma (MM). In 2012, carfilzomib was approved by Food and Drug Administration for the treatment of patients with relapsed...
07:44
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Use of vemurafenib in a patient unable to swallow whole: The treatment landscape for metastatic melanoma has increased dramatically in the past five years, with the pivotal discovery of activating BRAF mutations in half of all melanomas spurring the development for effective treatments that target mitogen-activated...
07:44
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Stability of four standardized preparations of methotrexate, cytarabine, and hydrocortisone for intrathecal use: IntroductionIntrathecal administration of methotrexate, cytarabine, and hydrocortisone is commonly used to treat and prevent central nervous system involvement in leukemias and lymphomas....
07:43
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Characterization and Management of Hedgehog Pathway Inhibitor-Related Adverse Events in Patients With Advanced Basal Cell Carcinoma: Vismodegib and sonidegib are Hedgehog pathway inhibitors (HPIs) approved for treatment of patients with advanced basal cell carcinoma. The adverse events (AEs) associated...
07:42
OtoRhinoLaryngology - Alexandros G. Sfakianakis
A Pilot Randomized Sham-Controlled Trial: This study evaluated the feasibility of conducting a randomized sham-controlled trial and collected preliminary data on safety and efficacy of acupuncture. The study supports the finding that a sham-controlled randomized trial evaluating acupuncture in dysphagia-related...
07:41
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Landmarks of the Frankfort horizontal plane: AbstractObjectivesThe goal was to investigate whether the three-dimensional (3D) reliability of the landmarks defining the Frankfort horizontal plane (FH) can be enhanced by reducing variance with the help of nearby anatomical structures.MethodsTwenty multislice...
07:41
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Aspirin and Cancer Risk: To the Editor Cao et al provided an emphasis regarding cancer prevention using aspirin in 2 large prospective cohort studies: the Nurses’ Health Study and Health Professionals Study. Overall cancer risk reduction was minimal, with a relative risk of 0.97 (95% CI, 0.94-0.99)....
07:40
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Overexpression of Dishevelled-2 contributes to proliferation and migration of human esophageal squamous cell carcinoma: AbstractDishevelled-2 (Dvl2) was associated with tumor cell proliferation and migration. We aimed to examine the mechanism of Dvl2 in esophageal squamous cell carcinoma (ESCC). Dvl2...
07:40
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Adenosine kinase facilitated astrogliosis-induced cortical neuronal death in traumatic brain injury: AbstractAdenosine kinase (ADK) plays a pivotal role in regulating brain function by regulating adenosine level, and ADK inhibition protects against neuronal damage in cerebral ischemia and epilepsy; however,...
07:38
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Similarity-Based Fusion of MEG and fMRI Reveals Spatio-Temporal Dynamics in Human Cortex During Visual Object Recognition: Every human cognitive function, such as visual object recognition, is realized in a complex spatio-temporal activity pattern in the brain. Current brain imaging techniques in isolation...
08:18
OroFacial Medicine by Alexandros G.Sfakianakis
AbstractObjectiveTo evaluate the frequency of peri-implant diseases and factors associated with its occurrence.Material and methodsOne hundred and fifty-five patients with dental implants were evaluated in this cross-sectional study. Dental implants were clinically and radiographically evaluated to diagnose...
08:17
Ενδοκρινολογία
Objective Glucagon-like peptide (GLP)-1 receptor agonist treatment improves β-cell function. In this study, we investigated whether the improvements are sustained during a 3-year treatment period. Research design and methods Sixty-nine metformin-treated type 2 diabetes patients were randomised to...
08:14
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Abstract IgE-mediated allergies, in particular allergic rhino-conjunctivitis and asthma, have reached epidemic proportions, affecting about one third of the population in developed countries. The most effective treatment for allergies is specific immunotherapy (SIT), which involves the injection of...
08:11
Human Diseases
Publication date: October 2016Source:Atmospheric Environment, Volume 143Author(s): Jiawei Li, Zhiwei HanThe horizontal and vertical distributions of aerosol extinction coefficient (AEC) and mass concentration over east China in October 2010 were investigated by using an online-coupled regional climate...
08:11
Human Diseases
Publication date: October 2016Source:Atmospheric Environment, Volume 143Author(s): Samresh Kumar, Ramya Sunder RamanTwelve hour integrated ambient fine particles (PM2.5) were collected over an Van Vihar National Park (VVNP), in Bhopal, Central India. Samples were collected on filter substrates every-other-day...
08:11
Human Diseases
Publication date: October 2016Source:Atmospheric Environment, Volume 143Author(s): S.M. Nazrul Islam, Peter L. Jackson, Julian AherneThe Peace River district of Northeastern British Columbia, Canada is a region of natural gas production that has undergone rapid expansion since 2005. In order to assess...
08:11
Human Diseases
Publication date: October 2016Source:Atmospheric Environment, Volume 143Author(s): L.F. Weissert, J.A. Salmond, J.C. Turnbull, L. SchwendenmannMeasurements of CO2 fluxes in temperate climates have shown that urban areas are a net source of CO2 and that photosynthetic CO2 uptake is generally not sufficient...
08:11
Human Diseases
Publication date: October 2016Source:Atmospheric Environment, Volume 143Author(s): Richard A. Dare, Rodney J. Potts, Alan G. WainThe statistical impact of including the process of wet deposition in dispersion model predictions of the movement of volcanic ash is assessed. Based on hypothetical eruptions...
07:56
Anaesthesiology
Summary Background Commonly used general anesthetics are considered to be neurotoxic to the developing rodent brain, leading to poor long-term outcome. However, it is unclear whether these rodent studies can be extrapolated to the human neonate. Given that anesthesia for urgent neonatal surgery...
07:42
Θεραπεία
Aim AZD1981 is an orally bioavailable CRTh2 receptor antagonist progressed to Phase II trials for the treatment of allergic asthma. Previously performed in vitro human hepatocyte incubations identified N-deacetylated AZD1981 as a primary metabolite. We report on metabolite exposure from a clinical...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ intitle:melanoma ]Surgical Management of Malignant Melanoma in Kankrej cowJV Vadalia, DT Fefar, PB Patel - INTAS POLIVET, 2016Malignant melanoma was reported in nine years old Kankrej cow with history of growth present just behind the right lateral elbow joint. On palpation, the...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ vestibular nerve, "vestibulocochlear nerve" , cranial nerve number VIII ]Neurosurgery Self-Assessment: Questions and AnswersRS Shah, TAD Cadoux-Hudson, JJ Van Gompel… - 2016Αυτή η Ειδοποίηση του Μελετητή Google σας προσφέρεται από τη GoogleΑκύρωση ειδοποίησηςΔημιουργία λίστας των...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ "ENT Emergencies" ][PDF] A STUDY OF FOREIGN BODY OESOPHAGUSR Meena, V Sikarwar, RS Bisht, A Arya - VOLUME-X NUMBER–I, JAN-JUNE, 2016... A STUDY OF FOREIGN BODY OESOPHAGUS * Richa Meena,** Vikas Sikarwar,*** RS Bisht,**** Amit Arya INTRODUCTION Foreign body of esophagus is a common...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ Throat's Diseases ][PDF] A Bacteriological Study of Acute Pharyngitis in Children Aged 5-15 Years with Special Reference to Streptococcal GroupingG Naveen, BV Peerapur - Int. J. Curr. Microbiol. App. Sci, 2016... milder diseases possibly there are several factors other than group...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ hearing ]High-Fidelity Hearing Instruments: Evaluating Listening Quality of a New Prototype Using a Method for Evaluating Modified Listening (MEML)F Denk, B Kollmeier, S Ernst - 2016A novel prototype of an individualized electronic earpiece providing acoustic transparency, ie, a...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ "selective neck" treatment ][PDF] VOLUME-X NUMBER–I, JAN-JUNE, 2016S Rautray, O Cuttack - Cell... al found that the presence of NEU- oncoprotein and the absence of HSP27 expression were associated with an increased rate of neck failure in patients treated with radiotherapy20....
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ "Hair cell" neural connection ]Speech and Audio Signal ProcessingAR JAYAN... as pressure variations. At the listener end, frequency components in the range of 20 Hz to 20 kHz produces vibrations in the basilar membrane located in the inner ear and undergoes a transduction to...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ "Training and Research Hospital" ][PDF] Bone-cement usage for Ossicular Reconstruction.MT Kalcioglu, T Cicek, L Uzun... 142 Bone-cement usage for Ossicular Reconstruction. M. Tayyar Kalcioglu, Tolga Cicek, Lokman Uzun Istanbul Medeniyet University, Faculty of Medicine, Department...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ intitle:VOICE ]17 Hacking the Voice of the Shuttle: The Growth and Death of a Boundary ObjectA Liu - Social Media Archeology and Poetics, 2016John N. Deely: A Thomistic Voice for SemioticsRL Lanigan - Chinese Semiotic Studies, 2016Abstract The article presents John Deely's philosophical...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ intitle:ALLERGY ][HTML] The epidemiologic characteristics of healthcare provider-diagnosed eczema, asthma, allergic rhinitis, and food allergy in children: a retrospective cohort studyDA Hill, RW Grundmeier, G Ram, JM Spergel - BMC Pediatrics, 2016Background The rates of childhood...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ intitle:"HEAD AND NECK" ][HTML] Functional MRI for the prediction of treatment response in head and neck squamous cell carcinoma: potential and limitationsAD King, HC Thoeny - Cancer Imaging, 2016Abstract Pre-treatment or early intra-treatment prediction of patients with head and...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ "Department of Otolaryngology" ]Adenoid cystic carcinoma: emerging role of translocations and gene fusions.PT Wysocki, E Izumchenko, J Meir, PK Ha, D Sidransky… - Oncotarget, 2016... Author information: (1)Department of Otolaryngology and Head & Neck Surgery, Johns Hopkins ...
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ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ intitle:"HEAD AND NECK" TUMORS chemotherapy ][HTML] Functional MRI for the prediction of treatment response in head and neck squamous cell carcinoma: potential and limitationsAD King, HC Thoeny - Cancer Imaging, 2016... would allow those sites to be targeted for more aggressive...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ Head & "Neck Surgery" ][PDF] Role of high resolution computed tomography of temporal bone in management of chronic suppurative otitis mediaJ Tak, AK Khilnani - … of Otorhinolaryngology and Head and Neck Surgery, 2016Background: High Resolution Computed Tomography (HRCT) has...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ intitle:"actinic keratosis" ]The continued use of sunscreen prevents the development of actinic keratosis in aged Japanese subjectsK Kunimoto, F Furukawa, M Uede, M Mizuno… - Experimental Dermatology, 2016Abstract It is well known that the trigger for actinic keratosis (AK) mainly...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ Soft palatal and pharyngeal lateral wall collapse ]Fetal medicine, fetal anaesthesia, and fetal surgeryF Russo, T Van Mieghem, J Deprest - Oxford Textbook of Obstetric Anaesthesia, 2016... 18 NT is the maximum thickness of the subcutaneous translucency between the skin and thesoft...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ Mimicking Carcinoma Larynx ][HTML] The Relationship Between Periodontal Disease and Neoplasms of the Oral Cavity: A Review ArticleM Nourelahi, B Roshannia, S Kameli, M Hormozi - Middle East Journal of …, 2016... Some reported cases of GSCC mimicking periodontal disease include...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ Malleus-to-footplate ossicular intitle:reconstruction prosthesis ][PDF] Bone-cement usage for Ossicular Reconstruction.MT Kalcioglu, T Cicek, L Uzun... References 1. Kalcioglu MT, Tan M, Fleerakkers J. The use of Bone-cement for ossicular chain defects. ... Autoclaving the ossicles...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ ENT Lasers,ORL LASERS ][PDF] VOLUME-X NUMBER–I, JAN-JUNE, 2016S Rautray, O Cuttack - Cell... Elizabeth's Medical Center Professor of Otolaryngology Tufts University School of Medicine ... useful in endoscopic ear surgery include piezoelectric bone dissection, lasers and Quantum...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ Bronchial foreign bodies ][PDF] Cardiothoracic surgical experience in GhanaM Tettey, M Tamatey, F Edwin - Cardiovascular Diagnosis and Therapy, 2016... These included 14 cases of esophageal perforation and 10 cases of impacted foreign bodies (8 of which were impacted dentures)....
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ Position dependent intitle:"obstructive sleep apnea" ][HTML] Obstructive sleep apnea and cardiovascular diseaseR Mehra, N Collop, G Finlay... Find synonyms. Find synonyms Find exact match. Obstructive sleep apnea and cardiovascular disease. Official reprint from UpToDate ® www.uptodate.com...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ "TASTE,SMELL" ]EFFECTIVE TEACHING AND LEARNINGPCN SUBRAMANI... students. Examples, analogies, and personal experiences also make learning come to life. Instructors should make full use of the senses (hearing, sight, touch, taste,smell, balance, rhythm, depth perception, and others)....
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ allintitle: Head Neck ][HTML] Functional MRI for the prediction of treatment response in head and neck squamous cell carcinoma: potential and limitationsAD King, HC Thoeny - Cancer Imaging, 2016Abstract Pre-treatment or early intra-treatment prediction of patients with head and...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ intitle:"Epstein-Barr virus" ][HTML] Amyloids and the Epstein Barr Virus Home/Nutrition/Amyloids and the Epstein Barr...T CochraneI am re-publishing a prior post regrading amyolids because we have received such widespread feed back on this week's post on EBV. Amyloids or truncated...
07:34
ΩΡΛ Ιατρικά Άρθρα απ' το Μελετητή
Ειδοποίηση Μελετητή:[ intitle:"MIDDLE EAR" TUMORS ]Interaction Between Allergy and Middle Ear InfectionJH Oh, WJ Kim - Current Allergy and Asthma Reports, 2016... demonstrated that TLR2 −/− and TLR4 −/− mice failed to induce tumor necrosis factor-α after NTHi challenge in the early phase ... the genes...
07:16
Anatomy Pathology
Abstract The endoskeleton of elasmobranchs (sharks and rays) is comprised largely of unmineralized cartilage, differing fundamentally from the bony skeletons of other vertebrates. Elasmobranch skeletons are further distinguished by a tessellated surface mineralization, a layer of minute, polygonal,...
07:14
News in OtoRhinoLaryngology - Alexandros G. Sfakianakis
If you have a job or a personal life that frequently places you in situations with loud music or noise, you may be suffering from a condition known as Tinnitus. If you have it, you probably would know it because symptoms include a constant, loud ringing sound in the ears. <strong>What is Tinnitus?</strong>...
07:04
The Oesophagus
Publication date: October 2016Source:Oral Oncology, Volume 61 Author(s): D.C. Ling, B.V. Chapman, J. Kim, G.W. Choby, P. Kabolizadeh, D.A. Clump, R.L. Ferris, S. Kim, S. Beriwal, D.E. Heron, U. Duvvuri ObjectiveIt has been postulated that treatment outcomes are similar between transoral robotic surgery...
06:51
Disaster Medicine
Debbie L. Humphries, Molly D Anderson, Padmavathy Venkatasubramanian http://ift.tt/2bhdSG2
06:51
Disaster Medicine
Komla Tsey, Kenny Lawson, Irina Kinchin, Roxanne Bainbridge, Janya McCalman, Felecia Watkin, Yvonne Cadet-James, Allison Rossetto http://ift.tt/2bhRMxi
06:47
Θεραπεία
Background Intravenous acetylcysteine is the treatment of choice for paracetamol poisoning. A previous UK study in 2001 found that 39% of measured acetylcysteine infusion concentrations differed by >20% from anticipated concentrations. In 2012 the UK Commission on Human Medicines made recommendations...
06:44
The Oesophagus
Abstract Background Helicobacter suis (H. suis) is the most prevalent gastric non-H. pylori Helicobacter species in humans. This bacterium mainly colonizes the stomach of pigs, but it has also been detected in the stomach of nonhuman primates. The aim of this study was to obtain better insights...
05:57
Speech and Hearing Disorders
This paper addresses the problem of automatic cry signal segmentation for the purposes of infant cry analysis. The main goal is to automatically detect expiratory and inspiratory phases from recorded cry signals. The approach used in this paper is made up of three stages: signal decomposition, features...
05:53
Physiology by Alexandros G.Sfakianakis
The early results of a new test of corticospinal tract (CST) integrity are reported in this issue of Clinical Neurophysiology (Andrews et al., 2016). The authors are to be congratulated for their thoughtfully conceived and precisely executed study. The manuscript is also highly readable and well-illustrated....
05:53
Physiology by Alexandros G.Sfakianakis
Electroencephalography (EEG) is the gold-standard test for diagnosing seizures, especially subclinical emergencies, including non-convulsive status epilepticus (NCSE) (DeLorenzo et al., 1998; Claassen et al., 2004; Laccheo et al., 2015). However, conventional scalp EEG with glued electrodes is very resource-intensive,...
08:22
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Abstract IgE-mediated allergies, in particular allergic rhino-conjunctivitis and asthma, have reached epidemic proportions, affecting about one third of the population in developed countries. The most effective treatment for allergies is specific immunotherapy (SIT), which involves the injection of...
08:22
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Increased survival, differentiation, and apoptotic death are common mechanisms relevant for both cancer and neurodegenerative diseases. Although these disorders are characterized by different manifestations, it appears that a common mechanism may be present which directs the fate of a cell to either...
08:15
THERAPY MEDICINE BY SFAKIANAKIS G.ALEXANDROS
AimAZD1981 is an orally bioavailable CRTh2 receptor antagonist progressed to Phase II trials for the treatment of allergic asthma. Previously performed in vitro human hepatocyte incubations identified N-deacetylated AZD1981 as a primary metabolite. We report on metabolite exposure from a clinical excretion...
08:15
OtoRhinoLaryngology
p62 modulates the intrinsic signaling of UVB-induced apoptosisvia ScienceDirect Publication: Journal of Dermatological SciencePublication date: September 2016Source:Journal of Dermatological Science, Volume 83, Issue 3Author(s): Sachiko Ito, Shintaro Kimura, Eiji Warabi, Yasuhiro Kawachi, Masanobu Yamatoji,...
08:15
OtoRhinoLaryngology
: A randomized, placebo-controlled, double-blind studyupdated on Wed Aug 17, 2016 14:47 via ScienceDirect Publication: Journal of Dermatological ScienceSource:Journal of Dermatological ScienceAuthor(s): Cecilie Scheuer, Hans-Christian Pommergaard, Jacob Rosenberg, Ismail GögenurBackgroundUltraviolet...
08:15
OtoRhinoLaryngology
: An anti-inflammatory treatment modality for initial hidradenitis suppurativavia ScienceDirect Publication: Journal of Dermatological SciencePublication date: Available online 10 August 2016Source:Journal of Dermatological ScienceAuthor(s): Schapoor Hessam, Michael Sand, Nina Mareike Meier, Thilo Gambichler,...
08:15
OtoRhinoLaryngology
Interdental papilla loss: treatment by hyaluronic acid gel injection: a case series: AbstractObjectivesThe purpose of this prospective clinical trial was to examine the clinical and patient outcomes following esthetic reconstruction of interdental papilla loss in anterior teeth, using an injectable,...
08:15
OtoRhinoLaryngology
in patients with atopic dermatitisvia ScienceDirect Publication: Journal of Dermatological ScienceSource:Journal of Dermatological ScienceAuthor(s): Y. Zhang, Y. Luo, W. Li, J. Liu, M. Chen, H. Gu, B. Wang, X. YaoBackgroundAtopic dermatitis (AD) is a common inflammatory skin disease, concomitant with...
08:15
OtoRhinoLaryngology
Prevalence of otologic signs and symptoms in adult patients with temporomandibular disorders: a systematic review and meta-analysis: AbstractObjectiveThis study aims to estimate the prevalence of otologic signs and symptoms in adult patients with temporomandibular disorders (TMD).Material and methodsSearch...
08:15
OtoRhinoLaryngology
Serum thyroid function, mortality and disability in advanced old age: The Newcastle 85+ study: The Journal of Clinical Endocrinology &Metabolism, Early Release. Simon HS Pearce1, Salman Razvi1, Mohammad E Yadegarfar2, Carmen Martin-Ruiz2, Andrew Kingston2, Joanna Collerton2, Theo J Visser3, Tom B...
08:15
OtoRhinoLaryngology
Characterization of Tumor Size Changes Over Time From the Phase 3 Study of Lenvatinib in Thyroid Cancer: The Journal of Clinical Endocrinology &Metabolism, Early Release. Bruce Robinson1, Martin Schlumberger2, Lori J. Wirth3, Corina E. Dutcus4, James Song5, Matthew H. Taylor6, Sung-Bae Kim7, Monika...
08:15
OtoRhinoLaryngology
IRAK1, a Target of miR-146b, Reduces Cell Aggressiveness of Human Papillary Thyroid Carcinoma: The Journal of Clinical Endocrinology &Metabolism, Early Release. Chen-Kai Chou1,2, Shun-Yu Chi3, Cai-Hua Huang1, Fong-Fu Chou3, Chao-Cheng Huang4, Rue-Tsuan Liu1,†, and Hong-Yo Kang2,5,†Address all correspondence...
08:15
OtoRhinoLaryngology
Risk Factors of 131I-Induced Salivary Gland Damage in Thyroid Cancer Patients: The Journal of Clinical Endocrinology &Metabolism, Early Release. Brynn Hollingsworth1, Leigha Senter2, Xiaoli Zhang3,5, Guy N. Brock3,5, Wael Jarjour4, Rebecca Nagy2,#, Pamela Brock2, Kevin R. Coombes5, Richard Kloos6,*,...
08:15
OtoRhinoLaryngology
68Ga-DOTATATE for Tumor Localization in Tumor-induced Osteomalacia: The Journal of Clinical Endocrinology &Metabolism, Early Release. Diala El-Maouche1,2, Samira M. Sadowski3,4, Georgios Z. Papadakis5, Lori Guthrie2, Candice Cottle-Delisle4, Roxanne Merkel4, Corina Millo5, Clara C. Chen6, Electron...
08:15
OtoRhinoLaryngology
Comprehensive screening of eight known causative genes in congenital hypothyroidism with gland-in-situ: The Journal of Clinical Endocrinology &Metabolism, Early Release. AK Nicholas1,*, EG Serra2,*, H Cangul3, S Alyaarubi4, I Ullah4, E Schoenmakers1, A Deeb5, AM Habeb6, M AlMaghamsi7, C Peters8,...
07:57
OtoRhinoLaryngology
PTH(1–34) for the primary prevention of post-thyroidectomy hypocalcemia: the THYPOS trial: The Journal of Clinical Endocrinology &Metabolism, Early Release. A. Palermo1,*, G. Mangiameli2,*, G. Tabacco1, F. Longo2, C. Pedone3, S.I. Briganti1, D. Maggi1, F. Vescini4, A. Naciu1, A. Lauria Pantano1,...
07:57
OtoRhinoLaryngology
The Vitamin D Receptor Regulates Tissue Resident Macrophage Response to Injury: Endocrinology, Early Release. Lige Songa, Garyfallia Papaioannoua, Hengguang Zhaoa, Hilary F. Luderera, Christine Millerc, Claudia Dall'Ossoc, Rosalynn M. Nazarianb, Amy J. Wagersc, and Marie B. DemayaAddress all correspondence...
07:57
OtoRhinoLaryngology
The circadian timing system and environmental circadian disruption: From follicles to fertility: Endocrinology, Early Release. Aritro Sen and Michael T. SellixAddress all correspondence and requests for reprints to: Michael T. Sellix Ph.D.,Department of Medicine, Division of Endocrinology and Metabolism,...
07:57
OtoRhinoLaryngology
Olaparib does not cause clinically relevant QT/QT c interval prolongation in patients with advanced solid tumours: results from two phase I studies: AbstractBackgroundSome therapeutic agents in oncology can be causally associated with specific cardiovascular events including QT/QTc interval prolongation....
07:57
OtoRhinoLaryngology
Estrogen and Microbiota Crosstalk: Should We Pay Attention?via ScienceDirect Publication: Trends in Endocrinology & MetabolismPublication date: Available online 20 August 2016Source:Trends in Endocrinology & MetabolismAuthor(s): Karen L. Chen, Zeynep Madak-ErdoganRecent advances have suggested...
07:57
OtoRhinoLaryngology
Silencing of fused toes homolog enhances cisplatin sensitivity in cervical cancer cells by inhibiting epidermal growth factor receptor-mediated repair of DNA damage: AbstractPurposeOverexpression of epidermal growth factor receptor (EGFR) is related to chemo-/radioresistance and poor prognosis in many...
07:57
OtoRhinoLaryngology
Generalized spastic dystonic cerebral palsy with regression of motor milestones due to congenital atlantoaxial dislocation: A diagnostic dilemma and rare association: Pavan Kumar Pelluru, Aniruddh Kumar PurohitIndian Journal of Cerebral Palsy 2016 2(1):48-50In spastic cerebral palsy cervical dystonia...
07:57
OtoRhinoLaryngology
Improvization of conventional cytology by centrifuged liquid-based cytology in oral exfoliative cytology specimen: Shwetha Nambiar, Veda Hegde, Nikhil Yadav, Kaveri HallikeriJournal of Cytology 2016 33(3):115-119Background: Exfoliative cytology is the microscopic examination of shed or desquamated cells...
07:57
OtoRhinoLaryngology
Sanjad-Sakati syndrome: Beyond the Middle-East: Chetana Sen, Sandip Pal, Prasenjit Sengupta, Asutosh Pal, Jacky Ganguly, Chiranjib Das, Debasish BasuIndian Journal of Cerebral Palsy 2016 2(1):54-57Sanjad-Sakati syndrome (OMIM 241410), also known as hypoparathyroidism-retardation-dysmorphism (HRD) syndrome,...
07:57
OtoRhinoLaryngology
Rare cytological findings: Maral Mokhtari, Perikala Vijayananda Kumar, Kamran HayatiJournal of Cytology 2016 33(3):120-124Background: Cystic papillary thyroid carcinoma (CPTC) is a variant of papillary carcinoma that has many mimickers in cytological grounds. Aim: To study the cytomorphologic features...
07:57
OtoRhinoLaryngology
A rare cytological diagnosis: Gopal Krishna Sawke, Tina Rai, Nilima SawkeJournal of Cytology 2016 33(3):166-168Calcinosis cutis is an uncommon condition characterized by the deposition of calcium salts in the subcutaneous tissues of the body. Calcifications can also occur in a variety of other clinical...
07:57
OtoRhinoLaryngology
Evaluation of cytomorphometric changes in tobacco users and diagnosed oral squamous cell carcinoma individuals: Urmila Udayashankar, Vijay Srinivas Guduru, Anuradha Ananthaneni, Sabitha Devi Ramisetty, Puneeth Horatti Kuberappa, Srilekha NamalaJournal of Cytology 2016 33(3):125-129Aims: To determine...
07:57
OtoRhinoLaryngology
A case report: Ajithakumari Kumaran, Sathi PuthenparambathJournal of Cytology 2016 33(3):172-174A 10-year-old boy presented with a swelling of the left mid upper arm of 1 month duration. Fine-needle aspiration (FNA) diagnosis of pseudosarcomatous lesion, suggestive of nodular fasciitis, was made and...
07:57
OtoRhinoLaryngology
Cytological grading: An alternative to histological grading in oral squamous cell carcinoma: Srilekha Namala, Vijay Srinivas Guduru, Anuradha Ananthaneni, Sabitha Devi, Puneeth Horrati Kuberappa, Urmila UdayashankarJournal of Cytology 2016 33(3):130-134Background: Micronuclei (MN) in oral exfoliative...
07:57
OtoRhinoLaryngology
Cytodiagnosis of disseminated histoplasmosis in an immunocompetent individual with molluscum contagiosum-like skin lesions and lymphadenopathy: Prajwala Gupta, Minakshi BhardwajJournal of Cytology 2016 33(3):163-165Disseminated histoplasmosis is caused by the dimorphic fungus Histoplasma capsulatum (H....
07:57
OtoRhinoLaryngology
Cytomorphologic spectrum of lymphocytic thyroiditis and correlation between cytological grading and biochemical parameters: KR Anila, Nileena Nayak, K JayasreeJournal of Cytology 2016 33(3):145-149Introduction: Chronic lymphocytic thyroiditis [Hashimoto thyroiditis (HT)] is a common thyroid lesion diagnosed...
07:57
OtoRhinoLaryngology
Evaluation of empiric antibiotic de-escalation in febrile neutropenia: IntroductionUp until 2010, the recommended duration of empiric broad-spectrum antibiotics for febrile neutropenia was until absolute neutrophil count (ANC) recovery. An updated guideline on the use of antimicrobial agents in neutropenic...
07:57
OtoRhinoLaryngology
Comorbidities among patients with cancer who do and do not develop febrile neutropenia during the first chemotherapy cycle: Patients receiving myelosuppressive chemotherapy with certain comorbidities are at increased risk of febrile neutropenia. A comprehensive evaluation of febrile neutropenia-related...
07:57
OtoRhinoLaryngology
Fatal pulmonary toxicity due to carfilzomib (Kyprolis™): IntroductionCarfilzomib (Kyprolis™) is a second-generation proteasome inhibitor for the treatment of relapsing multiple myeloma (MM). In 2012, carfilzomib was approved by Food and Drug Administration for the treatment of patients with relapsed...
07:57
OtoRhinoLaryngology
Comparative effectiveness of granulocyte colony-stimulating factors to prevent febrile neutropenia and related complications in cancer patients in clinical practice: A systematic review: IntroductionFebrile neutropenia (FN) is a serious side-effect of myelosuppressive chemotherapy. Several clinical trials...
07:50
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Purpose: Cancer treatments using tumor defects in DNA repair pathways have shown promising results but are restricted to small subpopulations of patients. The most advanced drugs in this field are Poly(ADP-Ribose) Polymerase (PARP) inhibitors (PARPi), which trigger synthetic lethality in tumors with...
07:50
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
ObjectiveGlucagon-like peptide (GLP)-1 receptor agonist treatment improves β-cell function. In this study, we investigated whether the improvements are sustained during a 3-year treatment period. Research design and methodsSixty-nine metformin-treated type 2 diabetes patients were randomised to the...
07:45
OtoRhinoLaryngology
Overexpression of Dishevelled-2 contributes to proliferation and migration of human esophageal squamous cell carcinoma: AbstractDishevelled-2 (Dvl2) was associated with tumor cell proliferation and migration. We aimed to examine the mechanism of Dvl2 in esophageal squamous cell carcinoma (ESCC). Dvl2...
07:45
OtoRhinoLaryngology
Adenosine kinase facilitated astrogliosis-induced cortical neuronal death in traumatic brain injury: AbstractAdenosine kinase (ADK) plays a pivotal role in regulating brain function by regulating adenosine level, and ADK inhibition protects against neuronal damage in cerebral ischemia and epilepsy; however,...
07:45
OtoRhinoLaryngology
Similarity-Based Fusion of MEG and fMRI Reveals Spatio-Temporal Dynamics in Human Cortex During Visual Object Recognition: Every human cognitive function, such as visual object recognition, is realized in a complex spatio-temporal activity pattern in the brain. Current brain imaging techniques in isolation...
07:45
OtoRhinoLaryngology
of Sjögren’s syndrome patientsvia ScienceDirect Publication: Journal of AutoimmunitySource:Journal of AutoimmunityAuthor(s): María-José Barrera, Sergio Aguilera, Isabel Castro, Juan Cortés, Verónica Bahamondes, Andrew F.G. Quest, Claudio Molina, Sergio González, Marcela Hermoso, Ulises Urzúa, Cecilia...
07:45
OtoRhinoLaryngology
in Switzerland: AbstractPurposeThe purpose of this study was to evaluate the present status of radiotherapy infrastructure and human resources in Switzerland and compute projections for 2020.Materials and methodsThe European Society of Therapeutic Radiation Oncology “Quantification of Radiation Therapy...
08:24
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Evidence of impaired function of orexin neurons has been found in individuals with cardiorespiratory disorders such as obstructive sleep apnea (OSA) and sudden infant death syndrome (SIDS), but the mechanisms responsible are unknown. Individuals with OSA and SIDS experience repetitive breathing cessations...
08:24
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Astrocyte derived lactate supports pathologically enhanced neuronal metabolism but its role under physiological conditions is still a matter of debate. Here, we determined the contribution of astrocytic neuronal lactate shuttle to maintenance of ion homeostasis and energy metabolism. We tested for the...
08:24
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Rhythmic oscillation in neurons can be characterized by various attributes such as the oscillation period and duty cycle. The values of these features depend on the amplitudes of the participating ionic currents, which can be characterized by their maximum conductances values. Recent experimental and...
08:24
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Previous neurophysiological studies performed in macaque monkeys have revealed complex somatosensory responses in the secondary somatosensory area (SII), such as large receptive fields (RFs) as well as bilateral ones. However, systematic analyses of neurons with large RFs have not been performed. In...
08:24
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Whether the CNS minimizes variability or effort in planning arm movements can be tested by measuring the preferred movement duration and end-point variability. Here, we conducted an experiment in which subjects performed arm-reaching movements without visual feedback in fast, medium, slow, and preferred...
08:21
medicinealexandrossfakianakis
The circadian timing system and environmental circadian disruption: From follicles to fertility: Endocrinology, Early Release. Aritro Sen and Michael T. Sellix Address all correspondence and requests for reprints to: Michael T. Sellix Ph.D., Department of Medicine, Division of Endocrinology and Metabolism,...
08:17
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Phlebitis: Inflammation of a vein. With phlebitis, there is infiltration of the walls of the vein and, usually, the formation of a clot (thrombus) in the vein (thrombophlebitis). Phlebitis in a leg, for example, causes the leg to swell with fluid (edema). Phlebitis can be superficial and not very serious,...
08:16
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Introduction Low back pain and neck pain are extremely prevalent and are responsible for an enormous burden of disease globally. Strong analgesics, such as opioid analgesics, are recommended by clinical guidelines for people with acute low back pain or neck pain who are slow to recover and require more...
08:16
health683
Itch in the General Internal Medicine Setting: A Cross-Sectional Study of Prevalence and Quality-of-Life Effects: Abstract Background Itch is a well-established symptom in cutaneous disease. However, little is known about the burden of itch outside the dermatology setting. Purpose To determine...
08:16
health683
Circular RNA expression in cutaneous squamous cell carcinoma via ScienceDirect Publication: Journal of Dermatological Science Publication date: September 2016Source:Journal of Dermatological Science, Volume 83, Issue 3 Author(s): Michael Sand, Falk G. Bechara, Thilo Gambichler, Daniel Sand, Michael...
08:16
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Introduction Functional gastrointestinal disorders (FGIDs) and FGID-related signs and symptoms have a fundamental impact on the psychosocial, physical and mental well-being of infants and their parents alike. Recent reviews and studies have indicated that FGIDs and related signs and symptoms may also...
08:16
health683
in German, Chinese and Japanese women manifests differently in all three groups depending on ethnic background, age and anatomical site via ScienceDirect Publication: Journal of Dermatological Science Publication date: September 2016Source:Journal of Dermatological Science, Volume 83, Issue 3 Author(s):...
08:16
health683
; a case-control study via ScienceDirect Publication: Journal of Dermatological Science Publication date: September 2016Source:Journal of Dermatological Science, Volume 83, Issue 3 Author(s): Rania Abdel Hay, Laila Rashed, Rehab Hegazy, Weam Rashwan, Nesrin Samir, Faisal Nour-Edin … Association of...
08:16
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Objectives To investigate the risk of emergency hospital admissions for violence (EHAV) associated with demographic and socioeconomic factors in Wales between 2007/2008 and 2013/2014, and to describe the site of injury causing admission. Design Database analysis of 7 years’ hospital admissions using...
08:16
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Purpose Few studies explore the long-term health and well-being of refugee children. A longitudinal cohort of refugee children was created to determine health and well-being outcomes over time. This article describes the methodology used to conduct this study, including sample characteristics and effectiveness...
08:16
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Introduction Accurate monitoring of acute coronary heart disease (CHD) is essential for understanding the effects of primary and secondary prevention and for planning of healthcare services. The ability to reliably monitor acute CHD has been affected by new diagnostic tests for myocardial infarction...
08:15
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Introduction Asthma is a common long-term disorder with a number of related comorbid conditions, which may affect asthma outcomes. There is a need for greater appreciation for understanding how these comorbidities interact with asthma in order to improve asthma outcomes. Objectives To systematically...
08:15
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Abstract The endoskeleton of elasmobranchs (sharks and rays) is comprised largely of unmineralized cartilage, differing fundamentally from the bony skeletons of other vertebrates. Elasmobranch skeletons are further distinguished by a tessellated surface mineralization, a layer of minute, polygonal,...
08:15
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Mitogen-inducible Gene 6 (Mig6) is a tumor suppressor and the disruption of Mig6 expression is associated with cancer development. Mig6 directly interacts with Epidermal Growth Factor Receptor (EGFR) to suppress the activation and downstream signaling of EGFR. Therefore, loss of Mig6 enhances EGFR-mediated...
08:15
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The cardiac Troponin cTnI-R145W mutation is associated with restrictive cardiomyopathy (RCM). Recent evidence suggests that this mutation induces perturbed myofilament length dependent activation (LDA) under conditions of maximal protein kinase A (PKA) stimulation. Some cardiac disease causing mutations,...
08:15
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
During cell division, accurate chromosome segregation is tightly regulated by Polo-Like Kinase 1 (PLK1) and opposing activities of Aurora B kinase and Protein Phosphatase 1 (PP1). However, the regulatory mechanisms underlying the aforementioned hierarchical signaling cascade during mitotic chromosome...
08:14
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
An increase in autophagy characterizes pancreatic carcinogenesis, but the signals that regulate this process are incompletely understood. Since canonical Wnt/β-catenin signaling is necessary for the transition from early to advanced pancreatic intraepithelial neoplasia (PanIN) lesions, we assessed whether...
08:14
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Rifampicin monooxygenase (RIFMO) catalyzes the N-hydroxylation of the natural product antibiotic rifampicin (RIF) to 2′-N-hydroxy-4-oxo-rifampicin, a metabolite with much lower antimicrobial activity. RIFMO shares moderate sequence similarity with well-characterized flavoprotein monooxygenases, but the...
08:14
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Abstract IgE-mediated allergies, in particular allergic rhino-conjunctivitis and asthma, have reached epidemic proportions, affecting about one third of the population in developed countries. The most effective treatment for allergies is specific immunotherapy (SIT), which involves the injection of...
08:14
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Recently, we used an ADP recycling approach to examine mouse skeletal muscle (SkM) mitochondrial function over respiratory states intermittent between state 3 and 4. We showed that respiration energized at complex II by succinate, in the presence of rotenone to block complex I, progressively increased...
08:14
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Oxfenicine is a carnitine-palmitoyl transferase 1b (CPT-1b)-specific inhibitor that has been shown to improve whole-body insulin sensitivity while suppressing fatty acid (FA) oxidation and increasing circulating FA. Since the white adipose tissue (WAT) is an organ that stores and releases FAs, this study...
08:14
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Influenza is a significant health concern worldwide. Viral infection induces local and systemic activation of the immune system causing attendant changes in metabolism. High-resolution metabolomics (HRM) uses advanced mass spectrometry and computational methods to measure thousands of metabolites inclusive...
08:14
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Purpose: Cancer treatments using tumor defects in DNA repair pathways have shown promising results but are restricted to small subpopulations of patients. The most advanced drugs in this field are Poly(ADP-Ribose) Polymerase (PARP) inhibitors (PARPi), which trigger synthetic lethality in tumors with...
08:14
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Objective We hypothesized that temporal lobe epilepsy (TLE) patients with and without hippocampal sclerosis (HS) showed differences in their limbic networks. This study aimed to evaluate the role of the thalamus in TLE patients with HS. Materials and methods Twenty-nine TLE patients with HS and 30...
08:14
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Multiple sclerosis (MS) is associated with inflammatory lesions in the brain and spinal cord. The detection of such inflammatory lesions using magnetic resonance imaging (MRI) is important in the consideration of the diagnosis and differential diagnoses of MS, as well as in the monitoring of disease...
08:14
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Objective Glucagon-like peptide (GLP)-1 receptor agonist treatment improves β-cell function. In this study, we investigated whether the improvements are sustained during a 3-year treatment period. Research design and methods Sixty-nine metformin-treated type 2 diabetes patients were randomised to...
08:14
Otolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174
Abstract Objective To evaluate the frequency of peri-implant diseases and factors associated with its occurrence. Material and methods One hundred and fifty-five patients with dental implants were evaluated in this cross-sectional study. Dental implants were clinically and radiographically evaluated...
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Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
G-quadruplex structures are composed of coplanar guanines and are found in both DNA and RNA. They are formed by the stacking of two or more G-quartets that are linked together by three loops. The current belief is that RNA G-quadruplexes include loops of l to 7 nucleotides in length, although recent...
08:14
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Publication date: 15 November 2016Source:Gene, Volume 593, Issue 1 Author(s): Jing Zhao, Yang Sun, Liubin Xiao, Yongan Tan, Lixin Bai In this study, we cloned a full-length cDNA encoding vitellogenin (Vg) in Spodoptera exigua. The complete Vg cDNA consists of 5694 nucleotides with a long open reading...
08:14
health683
p62 modulates the intrinsic signaling of UVB-induced apoptosis via ScienceDirect Publication: Journal of Dermatological Science Publication date: September 2016Source:Journal of Dermatological Science, Volume 83, Issue 3 Author(s): Sachiko Ito, Shintaro Kimura, Eiji Warabi, Yasuhiro Kawachi, Masanobu...
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health683
: A randomized, placebo-controlled, double-blind study updated on Wed Aug 17, 2016 14:47 via ScienceDirect Publication: Journal of Dermatological Science Source:Journal of Dermatological Science Author(s): Cecilie Scheuer, Hans-Christian Pommergaard, Jacob Rosenberg, Ismail Gögenur BackgroundUltraviolet...
08:13
health683
: An anti-inflammatory treatment modality for initial hidradenitis suppurativa via ScienceDirect Publication: Journal of Dermatological Science Publication date: Available online 10 August 2016Source:Journal of Dermatological Science Author(s): Schapoor Hessam, Michael Sand, Nina Mareike Meier, Thilo...
08:13
health683
in patients with atopic dermatitis via ScienceDirect Publication: Journal of Dermatological Science Source:Journal of Dermatological Science Author(s): Y. Zhang, Y. Luo, W. Li, J. Liu, M. Chen, H. Gu, B. Wang, X. Yao BackgroundAtopic dermatitis (AD) is a common inflammatory skin disease, concomitant...
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Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Publication date: 15 November 2016Source:Gene, Volume 593, Issue 1 Author(s): Walter W. Steiner, Chelsea L. Recor, Bethany M. Zakrzewski The M26 hotspot of the fission yeast Schizosaccharomyces pombe is one of the best-characterized eukaryotic hotspots of recombination. The hotspot requires a seven...
08:11
medicinealexandrossfakianakis
Estrogen and Microbiota Crosstalk: Should We Pay Attention? via ScienceDirect Publication: Trends in Endocrinology & Metabolism Publication date: Available online 20 August 2016Source:Trends in Endocrinology & MetabolismAuthor(s): Karen L. Chen, Zeynep Madak-ErdoganRecent...
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medicinealexandrossfakianakis
Olaparib does not cause clinically relevant QT/QT c interval prolongation in patients with advanced solid tumours: results from two phase I studies: Abstract Background Some therapeutic agents in oncology can be causally associated with specific cardiovascular events including QT/QTc interval prolongation....
08:11
medicinealexandrossfakianakis
Silencing of fused toes homolog enhances cisplatin sensitivity in cervical cancer cells by inhibiting epidermal growth factor receptor-mediated repair of DNA damage: Abstract Purpose Overexpression of epidermal growth factor receptor (EGFR) is related to chemo-/radioresistance and poor prognosis...
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Medicine….iliofanis
Human Molecular Genetics http://ift.tt/2c97cd1
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Medicine….iliofanis
Genome Biology and Evolution http://ift.tt/2bQP8ki
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Medicine….iliofanis
Cell Reports http://ift.tt/2bQQhIw
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Medicine….iliofanis
Scientific Reports http://ift.tt/2c97zUY
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Medicine….iliofanis
Circulation http://ift.tt/2c97IaV
07:35
Cancer by Sfakianakis Alexandros
Purpose: Cancer treatments using tumor defects in DNA repair pathways have shown promising results but are restricted to small subpopulations of patients. The most advanced drugs in this field are Poly(ADP-Ribose) Polymerase (PARP) inhibitors (PARPi), which trigger synthetic lethality in tumors with...
Wed Aug 24, 2016 23:18
Cancer
Metastases represent the main cause of death in melanoma patients. Despite the current optimized targeted therapy or immune checkpoint inhibitors the treatment of metastatic melanoma is unsatisfactory. Because of the poor prognosis of advanced melanoma there is an urgent need to identify new biomarkers...
Wed Aug 24, 2016 21:31
Head and Neck Cancers by Alexandros G. Sfakianakis
Publication date: Available online 24 August 2016Source:Brazilian Journal of Otorhinolaryngology Author(s): Liliana Costa, Laurentino Mendes Leal, Fernando Vales, Margarida Santos http://ift.tt/2bWf4gI
Wed Aug 24, 2016 21:22
Head and Neck Cancers by Alexandros G. Sfakianakis
Publication date: Available online 23 August 2016Source:Brazilian Journal of Otorhinolaryngology Author(s): Can Alper Çağici, Süheyl Asma, Mesut Şener http://ift.tt/2bnKIks
Wed Aug 24, 2016 21:21
Head and Neck Cancers by Alexandros G. Sfakianakis
Publication date: Available online 23 August 2016Source:Brazilian Journal of Otorhinolaryngology Author(s): Onur Ismi, Hakan Ozalp, Vural Hamzaoglu, Helen Bucioglu, Yusuf Vayısoglu, Kemal Gorur http://ift.tt/2bWdY4D
Wed Aug 24, 2016 21:21
Head and Neck Cancers by Alexandros G. Sfakianakis
Publication date: Available online 23 August 2016Source:Brazilian Journal of Otorhinolaryngology Author(s): Dongwon Kim, Kyung-Un Choi, Hak-Jin Kim, Kyu-Sup Cho http://ift.tt/2bnKKsD
Wed Aug 24, 2016 21:21
Head and Neck Cancers by Alexandros G. Sfakianakis
Publication date: Available online 24 August 2016Source:Brazilian Journal of Otorhinolaryngology Author(s): Maria Petri, Magdalena Chirilă, Sorana D. Bolboacă, Marcel Cosgarea IntroductionHealth-related quality of life (HRQoL) is used to denote that portion of the quality of life that is influenced...
Wed Aug 24, 2016 21:21
Head and Neck Cancers by Alexandros G. Sfakianakis
Abstract Clinical and radiological features or characteristics of posterior clinoid process (PCP) meningiomas have rarely been described because of their extreme scarcity and terminological confusion. Therefore, the strategies in the surgical intervention for PCP meningiomas have not been well established....
Wed Aug 24, 2016 21:21
Head and Neck Cancers by Alexandros G. Sfakianakis
Abstract Following extended endoscopic transsphenoidal approach (EETSA), cerebrospinal fluid (CSF) leak rate has been reported in the range of 5–50 %. Novel closure techniques, such as the nasoseptal flap and other multilayered repairs improved the outcomes significantly but took most of our focus....
Wed Aug 24, 2016 20:31
Head and Neck Cancers by Alexandros G. Sfakianakis
Objective To determine the safety and effectiveness of a new low-profile, laser-cut, closed-cell stent system in the treatment of complex intracranial aneurysms. Methods A total number of 43 patients with complex intracranial aneurysms were treated using 60 Acandis Acclino stent systems (follow-up...
Wed Aug 24, 2016 20:31
Head and Neck Cancers by Alexandros G. Sfakianakis
Objective To examine the safety and efficacy of mechanical thrombectomy using a retrievable stent for thromboembolic occlusion occurring during coil embolization of ruptured intracranial aneurysms. Methods Between June 2011 and June 2015, 631 consecutive patients with ruptured intracranial aneurysms...
Wed Aug 24, 2016 20:31
Head and Neck Cancers by Alexandros G. Sfakianakis
Background The preoperative localization of the feeder of spinal dural arteriovenous fistula (SDAVF) could simplify the diagnostic spinal angiographic procedure. Localization by non-contrast-enhanced MRI-based techniques is an attractive option. However, the usefulness of such an approach for evaluation...
Wed Aug 24, 2016 20:31
Head and Neck Cancers by Alexandros G. Sfakianakis
This cross-sectional study evaluates soluble CD molecules associated with disease activity and progression of vitiligo. http://ift.tt/2bO43dX
Wed Aug 24, 2016 20:31
Head and Neck Cancers by Alexandros G. Sfakianakis
In this issue of JAMA Dermatology, Speeckaert and colleagues report that levels of the soluble CD25 and CD27 molecules (sCD25 and sCD27) are elevated in the serum of patients with active vitiligo compared with patients with stable disease. In addition, sCD25 levels were found to be significantly lower...
Wed Aug 24, 2016 20:31
Head and Neck Cancers by Alexandros G. Sfakianakis
This cross-sectional study compares coronary artery calcium scores in patients with moderate to severe psoriasis, type 2 diabetes, and healthy controls. http://ift.tt/2bwB68w
Wed Aug 24, 2016 20:31
Head and Neck Cancers by Alexandros G. Sfakianakis
A woman in her 30s had discrete clustered painful blue papules on her face and extremities; the lesions had been present since childhood, but the size and intensity of pain had recently increased. What is your diagnosis? http://ift.tt/2bO401L
Wed Aug 24, 2016 20:18
Head and Neck Cancers by Alexandros G. Sfakianakis
The rapid replenishment of synaptic vesicles through endocytosis is crucial for sustaining synaptic transmission during intense neuronal activity. Synaptojanin (Synj), a phosphoinositide phosphatase, is known to play an important role in vesicle recycling by promoting the uncoating of clathrin following...
Wed Aug 24, 2016 20:17
Head and Neck Cancers by Alexandros G. Sfakianakis
Background The genetic drivers of multiple sclerosis (MS) clinical course are essentially unknown with limited data arising from severity and clinical phenotype analyses in genome-wide association studies. Methods Prospective cohort study of 127 first demyelinating events with genotype data, where...
Wed Aug 24, 2016 20:17
Head and Neck Cancers by Alexandros G. Sfakianakis
The canonical Wnt/β-catenin signaling pathway is crucial for blood–brain barrier (BBB) formation in brain endothelial cells. Although glucose transporter 1, claudin-3, and plasmalemma vesicular-associated protein have been identified as Wnt/β-catenin targets in brain endothelial cells, further downstream...
Wed Aug 24, 2016 20:17
Wed Aug 24, 2016 20:17
Head and Neck Cancers by Alexandros G. Sfakianakis
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Wed Aug 24, 2016 20:17
Head and Neck Cancers by Alexandros G. Sfakianakis
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Wed Aug 24, 2016 20:17
Head and Neck Cancers by Alexandros G. Sfakianakis
Selective attention plays an important role in identifying transient objects in a complex visual scene. Attentional control ability varies with observers. However, it is unclear what neural mechanisms are responsible for individual differences in attentional control ability. The present study used the...
Wed Aug 24, 2016 20:17
Head and Neck Cancers by Alexandros G. Sfakianakis
At birth, each mammalian skeletal muscle fiber is innervated by multiple motor neurons, but in a few weeks, all but one of those axons retracts (Redfern, 1970) and differential activity between inputs controls this phenomenon (Personius and Balice-Gordon, 2001; Sanes and Lichtman, 2001; Personius et...
Wed Aug 24, 2016 20:17
Head and Neck Cancers by Alexandros G. Sfakianakis
Seasonally breeding songbirds exhibit pronounced annual changes in song behavior, and in the morphology and physiology of the telencephalic neural circuit underlying production of learned song. Each breeding season, new adult-born neurons are added to the pallial nucleus HVC in response to seasonal changes...
Wed Aug 24, 2016 20:16
Head and Neck Cancers by Alexandros G. Sfakianakis
Brain-derived neurotrophic factor (BDNF) is essential for neuronal differentiation and survival. We know that BDNF levels decline in the brains of patients with Huntington's disease (HD), a neurodegenerative disease caused by the expression of mutant huntingtin protein (mHtt), and furthermore that administration...
Wed Aug 24, 2016 20:16
Head and Neck Cancers by Alexandros G. Sfakianakis
Glutamate neurotransmission refines synaptic connections to establish the precise neural circuits underlying sensory processing. Deleting metabotropic glutamate receptor 5 (mGluR5) in mice perturbs cortical somatosensory map formation in the primary somatosensory (S1) cortex at both functional and anatomical...
Wed Aug 24, 2016 20:16
Head and Neck Cancers by Alexandros G. Sfakianakis
P2X4 receptors are ATP-gated cation channels that are widely expressed in the nervous system. To identify P2X4 receptor-expressing cells, we generated BAC transgenic mice expressing tdTomato under the control of the P2X4 receptor gene (P2rx4). We found sparse populations of tdTomato-positive neurons...
Wed Aug 24, 2016 20:16
Head and Neck Cancers by Alexandros G. Sfakianakis
NMDA receptors are ligand-gated ion channels that underlie transmission at excitatory synapses and play an important role in regulating synaptic strength and stability. Functional NMDA receptors require two copies of the GluN1 subunit coassembled with GluN2 (and/or GluN3) subunits into a heteromeric...
Wed Aug 24, 2016 20:16
Head and Neck Cancers by Alexandros G. Sfakianakis
In many diseases, expression and ligand-dependent activity of the p75NTR receptor can promote pericyte and vascular dysfunction, inflammation, glial activation, and neurodegeneration. Diabetic retinopathy (DR) is characterized by all of these pathological events. However, the mechanisms by which p75NTR...
Wed Aug 24, 2016 20:16
Head and Neck Cancers by Alexandros G. Sfakianakis
Alterations in cAMP signaling are thought to contribute to neurocognitive and neuropsychiatric disorders. Members of the cAMP-specific phosphodiesterase 4 (PDE4) family, which contains >25 different isoforms, play a key role in determining spatial cAMP degradation so as to orchestrate compartmentalized...
Wed Aug 24, 2016 20:16
Head and Neck Cancers by Alexandros G. Sfakianakis
Most craniosensory afferents have unmyelinated axons expressing TRP Vanilloid 1 (TRPV1) receptors in synaptic terminals at the solitary tract nucleus (NTS). Neurotransmission from these synapses is characterized by substantial asynchronous EPSCs following action potential-synched EPSCs and high spontaneous...
Wed Aug 24, 2016 19:52
Head and Neck Cancers by Alexandros G. Sfakianakis
Scant information is available on the infectious causes of febrile illnesses in Armenia. The goal of this study was to describe the most common causes, with a focus on zoonotic and arboviral infections and rel... http://ift.tt/2bFo0oU
Wed Aug 24, 2016 19:52
Head and Neck Cancers by Alexandros G. Sfakianakis
Leptospirosis is a globally emerging zoonotic disease and an important public health threat in developing countries. Diagnosis of leptospirosis is mainly based on clinical presentations in resource poor countr... http://ift.tt/2bionaL
Wed Aug 24, 2016 19:52
Head and Neck Cancers by Alexandros G. Sfakianakis
Multidrug-resistant Pseudomonas aeruginosa has emerged as one of the most important healthcare-associated pathogens. Colistin is regarded as the last-resort antibiotic for multidrug-resistant Gram-negative bacter... http://ift.tt/2bFn1VE
Wed Aug 24, 2016 19:52
Head and Neck Cancers by Alexandros G. Sfakianakis
Publication date: Available online 24 August 2016Source:Journal of Cranio-Maxillofacial Surgery Author(s): Christian Mertens, Jose de San Jose Gonzalez, Christian Freudlsperger, Jens Bodem, Johannes Krisam, Jürgen Hoffmann, Michael Engel Patients with hemimaxillectomy defects after tumor surgery can...
Wed Aug 24, 2016 19:51
Head and Neck Cancers by Alexandros G. Sfakianakis
Publication date: Available online 23 August 2016Source:Journal of Cranio-Maxillofacial Surgery Author(s): Renato Marano, Alfio Jose Tincani The aim of this study was to compare the effectiveness of porous polyethylene, titanium mesh, and castor oil−derived biopolymer randomised in orbital reconstructions...
Wed Aug 24, 2016 19:51
Head and Neck Cancers by Alexandros G. Sfakianakis
Publication date: Available online 24 August 2016Source:Journal of Cranio-Maxillofacial Surgery Author(s): Stevo J. Najman, Vladimir J. Cvetković, Jelena G. Najdanović, Sanja Stojanović, Marija Đ. Vukelić-Nikolić, Ivica Vučković, Dragan Petrović Bone defects represent a serious problem in cranio-maxillofacial...
Wed Aug 24, 2016 19:46
Head and Neck Cancers by Alexandros G. Sfakianakis
Abstract Background Patients with multiple sclerosis (MS) or Crohn's disease (CD) being treated with natalizumab (Tysabri®, Biogen) who are planning to become pregnant or discover they are pregnant after exposure to natalizumab are currently advised to balance the potential benefits and potential risks...
Wed Aug 24, 2016 19:46
Head and Neck Cancers by Alexandros G. Sfakianakis
http://ift.tt/2bgMQbO
Wed Aug 24, 2016 19:46
Head and Neck Cancers by Alexandros G. Sfakianakis
The circuitry mediating top-down control of dopamine (DA) neurons in the ventral tegmental area (VTA) is exceedingly complex. Characterizing these networks will be critical to our understanding of fundamental behaviors, such as motivation and reward processing, as well as several disease states. Previous...
Wed Aug 24, 2016 19:21
Head and Neck Cancers by Alexandros G. Sfakianakis
Human stereopsis can operate in dense "cyclopean" images containing no monocular objects. This is believed to depend on the computation of binocular correlation by neurons in primary visual cortex (V1). The observation that humans perceive depth in half-matched random-dot stereograms, although these...
Wed Aug 24, 2016 19:21
Head and Neck Cancers by Alexandros G. Sfakianakis
In many sensory pathways, central neurons serve as temporal filters for timing patterns in communication signals. However, how a population of neurons with diverse temporal filtering properties codes for natural variation in communication signals is unknown. Here we addressed this question in the weakly...
Wed Aug 24, 2016 19:21
Head and Neck Cancers by Alexandros G. Sfakianakis
Hebbian-type learning rules, which underlie learning and refinement of neuronal connectivity, postulate input specificity of synaptic changes. However, theoretical analyses have long appreciated that additional mechanisms, not restricted to activated synapses, are needed to counteract positive feedback...
Wed Aug 24, 2016 19:18
Cancer
Abstract Background Novel immunotherapy modalities significantly improve survival of patients with metastatic melanoma. However, CTLA-4-blocking monoclonal antibody ipilimumab is effective only in a small proportion of patients. Biomarkers for prediction of treatment response are indispensably...
Wed Aug 24, 2016 19:18
Cancer
Abstract Objective Patients receiving radiation therapy (RT) for head and neck cancers often experience severe weight loss that can lead to difficulty in daily setup. The primary purpose of this study was to understand the impact of weight loss on patient's setup in the era of image guided radiation...
Wed Aug 24, 2016 19:18
Cancer
Combined hepatocellular and cholangiocarcinoma (CHC) is a unique subtype of liver cancer comprising both hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC); however, its cellular origin r... from Cancer via ola Kala on Inoreader http://ift.tt/2bVQfRZ via IFTTT
Wed Aug 24, 2016 19:18
Cancer
Abstract Purpose To compare annual and monthly prevalence of psychotropic drug (PD) dispensing and the number and duration of psychotropic treatment episodes among people with and without cancer over a 2-year follow-up. Methods We studied the following two cohorts of adult patients affiliated with...
Wed Aug 24, 2016 19:18
Cancer
Publication date: October 2016Source:Cancer Epidemiology, Volume 44 Author(s): Muhammad Asif Qureshi, Talat Mirza, Saeed Khan, Bushra Sikandar, Maria Zahid, Marium Aftab, Sehrish Mohsin, Shaheen Sharafat, Lubna Avesi, Saba Hassan National level population-based cancer data have never been published...
OtoRhinoLaryngology & Medicine,New Articles,August 25th,2016
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