Serum collagenase-2 and BMI levels in pregnant women with striae gravidarum

Summary

Objective

Striae gravidarum is a form of scarring on the skin observed during pregnancy and can cause serious cosmetic problems. Striae gravidarum may be influenced by hormonal changes, although the etiology is not clear. The aim of this study was to investigate whether body mass index (BMI) and serum collagenase-2 levels in pregnant women are related to the development of striae gravidarum.

Methods

Thirty pregnant women with striae, 30 pregnant women without striae, and 32 health controls were enrolled in the study.

Results

BMI and serum collagenase-2 levels were measured in the participants.

Conclusion

Pregnant women with striae gravidarum had increased serum collagenase-2 and BMI levels when compared to pregnant women without striae gravidarum and healthy controls (P < 0.05). The increase in serum collagenase-2 levels was related to the development of striae gravidarum alone, or secondary to BMI increase.

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