Vitamin E in the treatment of osteoradionecrosis of the jaws

The use of vitamin E supplements for the treatment of osteoradionecrosis of the jaws was recommended by Delanian et al. when they proposed their fibroatrophic theory of the disease.1 It was their understanding of its biological and cellular processes that led to the decision to manage it with pentoxyphylline, tocopherol, and clodronate.

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