Chin symphysis bone, allograft, and platelet rich fibrin: Whether the combination is effective in repair of alveolar cleft?

Publication date: Available online 26 December 2016
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Bijan Movahedian Attar, Navid Naghdi, Milad Etemadi Sh, Mojdeh Mehdizadeh
PurposeSecondary grafting of alveolar defects with iliac crest bone is a common treatment method in cleft patients. The aim of this study was to evaluate the effectiveness of the combination of symphysis bone, allograft and platelet rich fibrin (PRF) in regeneration of alveolar defects compared to iliac bone graft.Methods and materialsIn this randomized clinical trial, patients with unilateral alveolar defect were divided randomly into two categories. Group A comprised the patients considered for treatment with the combination of chin symphysis bone + allogenic bone material + L-PRF. Group B comprised the patients who were considered for iliac bone graft. Cone beam computed tomography (CBCT) before treatment and 1 year post-operation were used for measurement of bone formation (bone volume in cm³). The data was analyzed by Paired T-test and Chi square via SPSS 23 software. P value less than 0.05 was considered as significant.ResultsTen patients were included in each group (6 males in group A, and 5 males in group B). The mean age of patients in groups A and B were 9.5 ± 1.5 and 9.9 ± 1.9 years, respectively. The mean volume of alveolar defects in group A was 0.89 ± 0.29 cm3. This amount in group B was 0.95 ± 0.27 cm³. The percentages of bone regeneration in group A and B were 69.5 and 73.8%, respectively.ConclusionIt seems that "chin symphysis bone + allogenic bone material + PRF" is a proper combination for bone regeneration in alveolar defects with small to moderate volume range.



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