Do vasoactive agents negatively influence the success of Maxillo-Facial microvascular free-flap surgery: A retrospective audit

Introduction: Microvascular free-flap surgery has become the gold standard in Head and Neck oncology reconstruction. Current literature states free-flap success rates of 95%. Evidence suggests that adverse effect on blood flow to the flap remains the primary cause of failure, which may be linked to the type of vasoconstrictor used during anaesthesia. The premise of this audit is to assess the success rate of microsurgical free-flaps in the Oral and Maxillo-facial Surgery department at Royal Derby Hospital (RDH) and review whether the administration of vasoactive agents has an effect on this.

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