Prognostic role of margin status in open and CO2 laser cordectomy for T1a–T1b glottic cancer

Publication date: Available online 24 December 2016
Source:Brazilian Journal of Otorhinolaryngology
Author(s): Vincenzo Landolfo, Carmine Fernando Gervasio, Giuseppe Riva, Massimiliano Garzaro, Rita Audisio, Giancarlo Pecorari, Roberto Albera
IntroductionCordectomy by laringofissure and transoral laser surgery has been proposed for the treatment of early glottic cancer.ObjectivesThe aim of this retrospective study was to evaluate the prognostic value of margin status in 162 consecutive cases of early glottic carcinoma (Tis–T1) treated with CO2 laser endoscopic surgery (Group A) or laryngofissure cordectomy (Group B), and to compare the oncologic and functional results.MethodsClinical prognostic factors, local recurrence rate according to margin status, overall survival and disease-free survival were analyzed.ResultsMargin status is related to recurrence rate in both groups (p<0.05) without significant differences between open and laser cordectomy (p>0.05). The 5 years overall survival and disease-free survival were respectively 90.48% and 85.71% in Group A; 88.14% and 86.44% in Group B (p>0.05). Lower tracheostomy rate, earlier recovery of swallowing function and shorter hospital stay were observed in Group A (p<0.05).ConclusionsMargin status has a prognostic role in T1a–T1b glottic cancer. Transoral laser surgery showed similar oncologic results of open cordectomy, with better functional outcomes.



http://ift.tt/2hSWFDG