Regulatory T Cell Populations in Children Are Affected by Age and Food Allergy Diagnosis

Publication date: Available online 23 May 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Benjamin T. Prince, Ashley L. Devonshire, Kristin A. Erickson, Jenna Bergerson, Dalia Fuleihan, Christine Szychlinski, Robert P. Schleimer, Paul J. Bryce, Anne Marie Singh

Teaser

Young food allergic children have decreased regulatory T cell (Treg) percentages. Only Tregs from healthy controls demonstrated age-related increases in their expression of the gut-associated chemokine receptor CCR6, which may be important in maintaining oral tolerance to foods and preventing the development of allergic disease.


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