Does guided bone regeneration prevents unfavurable bone shape in distraction gap ?

Publication date: Available online 5 August 2017
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Umut Demetoglu, Alper Alkan., Erdem Kiliç, Mustafa Ozturk, Suheyb Bilge
PurposeComplications related to distraction osteogenesis may cause the degradation of newly regenerated bone. Additionally, an unfavorable shape of regenerated bone at the distraction gap can reduce the quantity of regenerated bone. The aim of this study was to prevent unfavorable shapes of regenerated bone with guided bone regeneration during distraction.Materials and methodsBilateral alveolar distraction was performed in 10 beagle dog mandibles. One side of the mandibles formed the experimental group and the other side served as the control group. In the experimental group, guided bone regeneration was performed simultaneously with distraction osteogenesis. In the control group, only alveolar distraction was applied. At the end of a 1-week latent period, all mandibles were distracted 10 mm (1 mm/d), and 3 months were then allowed for consolidation. After consolidation, all animals were sacrificed and the shape of regenerated bone was determined to be favorable or unfavorable. Densitometric evaluation and area measurements were performed with computed tomography. Statistical evaluation was performed using the independent t-test, with a significance level of p < 0.05.ResultsIn the experimental group, there was no unfavorable bone shape in the distraction gap and the new bone had similar surface and volume as the segments, whereas in the control group, four subjects had unfavorable bone shape in the distraction gap, and the other four subjects showed favorable bone healing with no defect. The surface area of the regenerating bone in the experimental group was significantly higher than that in the control group. Surface area differed significantly between the experimental and control groups (p < 0.05). Densitometric values did not differ between groups (p < 0.05).ConclusionsConcomitant use of guided bone regeneration with distraction osteogenesis may be considered an optimal way to generate a favorable bone shape within the distraction gap.



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