Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τετάρτη 16 Αυγούστου 2017

Myxofibrosarcoma in Head and Neck: Case Report of Unusually Aggressive Presentation

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Publication date: Available online 16 August 2017
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Anastasiya Quimby, Abigail Estelle, Arun Gopinath, Rui Fernandes
Myxofibrosarcoma (MFS) is a malignant fibroblastic tumor that primarily affects lower and upper extremities. It is usually described as a slow growing tumor with high recurrence rates but low metastatic potential. Reported incidence of head and neck MFS is 2-4% rarely presenting with distant metastases[1, 2]. We present a case of maxillary MFS in a 72-year-old woman whose disease progression followed an atypical course with an extremely rapid rate of growth and early pulmonary and central nervous system lesions. Due to pulmonary symptoms as initial presentation, arriving at a final diagnosis was a challenge. Various diagnostic modalities and multidisciplinary collaboration were required. The disease course and management are outlined. To our knowledge, this is the first case of MFS originating in the maxillary alveolus with multiple metastases including brain and lungs in the early course of the disease.



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