Prognostic significance of soft tissue deposits in laryngeal carcinoma

Publication date: Available online 31 July 2017
Source:Brazilian Journal of Otorhinolaryngology
Author(s): Omer Afsin Ozmen, Melih Alpay, Ozlem Saraydaroglu, Uygar Levent Demir, Fikret Kasapoglu, Hamdi Hakan Coskun, Oguz Ibrahim Basut
IntroductionSoft tissue deposits (STD) is tumorous islands apart from lymph nodes and occasionally diagnosed in neck dissection specimens. Their importance has begun to be recognized, however, their value has not been investigated in laryngeal cancer as a single tumor site.ObjectiveTo investigate the prognostic value of STD in patients with laryngeal carcinoma.MethodsMedical records of 194 patients with laryngeal carcinoma who were treated primarily by surgery and neck dissection were reviewed. Prognostic significance of STD was assessed along with other clinical and pathological findings. Recurrence rates, overall and disease-specific survival rates were examined.ResultsThe incidence of STD was found to be 7.2% in laryngeal carcinoma. N stage was more advanced in patients who had STD. Regional recurrence rate was higher and disease specific and overall survivals rates were significantly lower in patients with STD in univariate analysis. However, in multivariate analysis, STD was not found as an independent risk factor.ConclusionIn laryngeal carcinoma, STD was diagnosed in patients with more advanced neck disease and its significance was lesser than other factors including extranodal extension.



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