The usefulness of investigating the possible underlying conditions in rosacea

Abstract

The paper entitled "Rosacea and demodicidosis with gain of function mutation in STAT1″ by Second et al.¹ is of indubitable interest and prompted us to make some observations. The Authors described a patient with cutaneous and ocular rosacea that they related to demodicidosis since oral ivermectin improved the cutaneous lesions¹. However, the Authors did not demonstrate by skin scraping nor by standardized skin surface biopsy (SSSB) an excessive number of Demodex folliculorum (DF) mites in the pilosebaceous units to justify an oral antiparasitic treatment as a drug of first choice¹.

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