Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Πέμπτη 14 Σεπτεμβρίου 2017

Hashimoto's thyroiditis – an independent risk factor for papillary carcinoma

Publication date: Available online 14 September 2017
Source:Brazilian Journal of Otorhinolaryngology
Author(s): Barbora Uhliarova, Andrej Hajtman
IntroductionThe link between Hashimoto's thyroiditis (HT) and thyroid carcinoma (TC) has long been a topic of controversy.ObjectiveThe aim of our study was to determine the prevalence of TC and HT coexistence in histopathologic material of thyroidectomized patients.MethodsIn a retrospective study, the clinicohistopathologic data of 2117 patients (1738 females/379 males), who underwent total or partial thyroidectomy for thyroid gland disorder at a single institution from the 1st of January 2005 to the 31st of December 2014 were analyzed.ResultsThyroid carcinoma was detected in 318 cases (15%) and microcarcinoma (thyroid cancer ≤10mm in diameter) (TMC) was found in permanent sections in 169 cases (8%). Hashimoto's thyroiditis was detected in 318 (15%) patients. HT was significantly more often associated with thyroid carcinoma and microcarcinoma compare to benign condition (p=0.048, p=0.00014, respectively). Coexistence of HT and TC/TMC did not affect tumor size (p=0.251, p=0.098, respectively), or tumor multifocality (p=0.831, p=0.957, respectively). Bilateral TMC was significantly more often detected when HT was also diagnosed (p=0.041), but presence of HT did not affect bilateral occurrence of TC (p=0.731).ConclusionHashimoto's thyroiditis is associated with significantly increased risk of developing thyroid carcinoma, especially thyroid microcarcinoma.



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